The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2005
The DotL protein, a member of the TraG-coupling protein family, is essential for viability of Legionella pneumophila strain Lp02, Benjamin A. Buscher, Gloria M. Conover, Jennifer L. Miller, Sinae A. Vogel, Stacey N. Meyers, Ralph R. Isberg, and Joseph P. Vogel
Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex, Goran O. Bylund and Peter M. J. Burgers
The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein, David A. Canton, Mary Ellen K. Olsten, Kyoungtae Kim, Amanda Doherty-Kirby, Gilles Lajoie, John A. Cooper, and David W. Litchfield
Antioxidant supplementation for the prevention of kwashiorkor in Malawian children: Randomised, double blind, placebo controlled trial, Heather Ciliberto, Michael Ciliberto, Andree Briend, Per Ashorn, Dennis Bier, and Mark Manary
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model, John R. Cirrito, Rashid Deane, Anne M. Fagan, Michael L. Spinner, Maia Parsadanian, Mary Beth Finn, Hong Jiang, Julie L. Prior, Abhay Sagare, Kelly R. Bales, Steven M. Paul, Berislav V. Zlokovic, David Piwinca-Worms, and David M. Holtzman
Periacetabular osteotomy for the treatment of severe acetabular dysplasia, John C. Clohisy, Susan E. Barrett, J. Eric Gordon, Eliana D. Delgado, and Perry L. Schoenecker
Architecture and adhesive activity of the Haemophilus influenzae Hsf adhesin, Shane E. Cotter, Hye-Jeong Yeo, Twyla Juehne, and Joseph W. St. Geme III
Identification of functional transcription factor binding sites using closely related Saccharomyces species, Scott W. Doniger, Juyoung Huh, and Justin C. Fay
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood, Victor A. Drover, Mohammad Ajmal, Fatiha Nassir, Nicholas O. Davidson, Andromeda M. Nauli, Daisy Sahoo, Patrick Tso, and Nada A. Abumrad
Use of several inducer and substrate antibiotic combinations in a disk approximation assay format to screen for AmpC induction in patient isolates of Pseudomonas aeruginosa, Enterobacter spp., Citrobacter spp., and Serratia spp., W. Michael Dunne Jr. and Daniel J. Hardin
Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures, Gerald Dunn, Anthony L. Hinrichs, Sarah Bertelsen, Carol H. Jin, John SK Kauwe, Brian K. Suarez, and Laura J. Bierut
A model of the statistical power of comparative genome sequence analysis, Sean R. Eddy
‘‘Antedisciplinary’’ science, Sean R. Eddy
Gene finding in the chicken genome, Eduardo Eyras, Alexandre Reymond, Robert Castelo, Jacqueline M. Bye, Francisco Camara, Paul Flicek, Elizabeth J. Huckle, Genis Parra, David D. Shteynberg, Carine Wyss, Jane Rogers, Stylianos E. Antonarakis, Ewan Birney, Roderic Guigo, and Michael R. Brent
Effects of combined diethylcarbamazine and albendazole treatment of bancroftian filariasis on parasite uptake and development in Culex pipiens L., Hoda A. Farid; Ragaa E. Hammad; Marah M. Hassan; Reda M.R, Ramzy; Maged El Setouhy; and Gary J. Weil
Evidence for domesticated and wild populations of saccharomyces cerevisiae, Justin C. Fay and Joseph A. Benavides
The LIM protein Ajuba influences interleukin-1-induced NF-κB activation by affecting the assembly and activity of the protein kinase Cζ/p62/TRAF6 signaling complex, Yungfeng Feng and Gregory D. Longmore
Dominant negative effects of the AML1/ETO fusion oncoprotein, Timothy S. Fenske, Gina Pengue, and Timothy A. Graubert
Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases, Angela M. Ferguson, Lynn S. White, Peter J. Donovan, and Helen Piwnica-Worms
Patterns and predictors of inpatient falls and fall-related injuries in a large academic hospital, Irene D. Fischer, Melissa J. Krauss, William Claiborne Dunagan, Stanley Birge, Eileen Hitcho, Shirley Johnson, Eileen Constantinou, and Victoria J. Fraser
Pseudomonas aeruginosa acquires biofilm-like properties within airway epithelial cells, Raquel Garcia-Medina, W. Michael Dunne, Pradeep K. Singh, and Steven L. Brody
How the cell deals with DNA nicks, Parie Garg and Peter M.J. Burgers
Computational technique for improvement of the position-weight matrices for the DNA/protein binding sites, Naum I. Gershenzon, Gary D. Stormo, and Illya P. Ioshikhes
Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics, Jason Gertz, Linda Riles, Peter Turnbaugh, Su-Wen Ho, and Barak A. Cohen
Analysis of memory T lymphocyte activity following stimulation with overlapping HLA-A*2402, A*0101 and Cw*0402 restricted CMV pp65 peptides, Monica Ghei, David F. Stroncek, and Maurizio Provenzano
Reporting quality of randomized trials in the diet and exercise literature for weight loss, Cheryl A. Gibson, Erik P. Kirk, James D. LeCheminant, Bruce W. Bailey Jr, Guoyuan Huang, and Joseph E. Donnelly
The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression, Nathan A. Gillespie, John B. Whitfield, Ben Williams, Andrew C. Heath, and Nicholas G. Martin
Upper-extremity phocomelia reexamined: A longitudinal dysplasia, Charles A. Goldfarb, Paul R. Manske, Riccardo Busa, Janith Mills, Peter Carter, and Marybeth Ezaki
Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites, Jennifer L. Gordon and L David Sibley
Comprehensive treatment of late-onset tibia vara, J. Eric Gordon, Fred P. Heidenreich, Chris J. Carpenter, Jill Kelly-Hahn, and Perry L. Schoenecker
Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: Evidence from a twin design, Julia D. Grant, Jeffrey F. Scherrer, Michael T. Lynskey, Michael J. Lyons, Seth A. Eisen, Ming T. Tsuang, William R. true, and Kathleen K. Bucholz
Rfam: Annotating non-coding RNAs in complete genomes, Sam Griffiths-Jones, Simon Moxon, Mhairi Marshall, Ajay Khanna, Sean R. Eddy, and Alex Bateman
The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells, Thomas E. Grys, Matthew B. Siegel, Wyndham W. Lathem, and Rodney A. Welch
Involvement of human MOF in ATM function, Arun Gupta, Girdhar G. Sharma, Charles S. H. Young, Manjula Agarwal, Edwin R. Smith, Tanya T. Paull, John C. Lucchesi, Kum Kum Khanna, Thomas Ludwig, and Tej K. Pandita
Paternal alcoholism and offspring conduct disorder: Evidence for the 'common genes' hypothesis, Jon R. Haber, Theodore Jacob, and Andrew C. Heath
Yersinia enterocolitica invasin-dependent and invasin-independent mechanisms of systemic dissemination, Scott A. Handley, Rodney D. Newberry, and Virginia L. Miller
Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant, J. Hiemenz, P. Cagnoni, D. Simpson, S. Devine, N. Chao, J. Keirns, W. Lau, D. Facklam, and D. Buell
Genomics in C. elegans: So many genes, such a little worm, LaDeana W. Hillier, Alan Coulson, John I. Murray, Zhirong Bao, John E. Sulston, and Robert H. Waterston
Multipoint identity-by-descent computations for single-point polymorphism and microsatellite maps, Anthony L. Hinrichs, Sarah Bertelsen, Laura J. Bierut, Gerald Dunn, Carol H. Jin, John S. Kauwe, and Brian K. Suarez
Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death, William A. Holtz, Jay M. Turetzky, and Karen L. O'Malley
Ultrasonic songs of male mice, Timothy E. Holy and Zhongsheng Guo
Punctuated duplication seeding events during the evolution of human chromosome 2p11, Julie E. Horvath, Cassandra L. Gulden, Rhea U. Vallente, Marla Y. Eichler, Mario Ventura, John D. McPherson, Tina A. Graves, Richard K. Wilson, Stuart Schwartz, Mariano Rocchi, and Evan E. Eichler
Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli, David A. Hunstad, Sheryl S. Justice, Chia S. Hung, Scott R. Lauer, and Scott J. Hultgren
Mitochondrial energy metabolism in heart failure: A question of balance, Janice M. Huss and Daniel P. Kelly
The type Iα inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane, Ivan Ivetac, Adam D. Munday, Marina V. Kisseleva, Xiang-Ming Zhang, Susan Luff, Tony Tiganis, James C. Whisstock, Tony Rowe, Phillip W. Majerus, and Christina A. Mitchell
An improved internal mammary irradiation technique in radiation treatment of locally advanced breast cancers, Jian-Yue Jin, Eric E. Klein, Feng-Ming Kong, and Zuofeng Li
The multiple biological roles of the 3’→5’ exonuclease of Saccharomyces cerevisiae DNA polymerase δ require switching between the polymerase and exonuclease domains, Yong Hawn Jin, Parie Garg, Carrie M. W. Stith, Hanan Al-Refai, Joan F. Sterling, Laura J. W. Murray, Thomas A. Kunkel, Michael A. Resnick, Peter M. Burgers, and Dmitry A. Gordenin
Use of in vivo-induced antigen technology for identification of Escherichia coli O157:H7 proteins expressed during human infection, Manohar John, Indira T. Kudva, Robert W. Griffin, Allen W. Dodson, Bethany McManus, Bryan Krastins, David Sarracino, Ann Progulske-Fox, Jeffrey D. Hillman, Martin Handfield, Phillip I. Tarr, and Stephen B. Calderwood
The IrgA homologue adhesin Iha is an Escherichia coli virulence factor in murine urinary tract infection, James R. Johnson, Srdjan Jelacic, Laura M. Schoening, Connie Clabots, Nurmohammad Shaikh, Harry L.T. Mobley, and Phillip I. Tarr
Arthrodesis techniques in the management of stage-II and III acquired adult flatfoot deformity, Jeffrey E. Johnson and James R. Yu
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA Is required for pilus biogenesis in Escherichia coli, Sheryl S. Justice, David A. Hunstad, Jill Reiss Harper, Amy R. Duguay, Jerome S. Pinkner, James Bann, Carl Frieden, Thomas J. Silhavy, and Scott J. Hultgren
An antagonist peptide mediates positive selection and CD4 lineage commitment of MHC class II–restricted T cells in the absence of CD4, Henry Kao and Paul M. Allen
Comparing low coverage random shotgun sequence data from Brassica oleracea and Oryza sativa genome sequence for their ability to add to the annotation of Arabidopsis thaliana, Manpreet S. Katari, Vivekanand Balija, Richard K. Wilson, Robert A. Martienssen, and W. Richard McCombie
Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice, Andrew L. Kau, Steven M. Martin, William Lyon, Ericka Hayes, Michael G. Caparon, and Scott J. Hultgren
The efficacy of short tandem repeat polymorphisms versus single-nucleotide polymorphisms for resolving population structure, John SK Kauwe, Sarah Bertelsen, Laura Jean Bierut, Gerald Dunn, Anthony L. Hinrichs, Carol H. Jin, and Brian K. Suarez
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii, Asis Khan, Sonya Taylor, Chunlei Su, Aaron J. Mackey, Jon Boyle, Robert Cole, Darius Glover, Keliang Tang, Ian T. Paulsen, Matt Berriman, John C. Boothroyd, Elmer R. Pfefferkorn, J. P. Dubey, James W. Ajioka, David S. Roos, John C. Wooton, and L. D. Sibley
Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains, A. Khan, C. Su, M. German, G. A. Storch, D. B. Clifford, and L. David Sibley
Eradication of methicillin-resistant Staphylococcus aureus from a neonatal intensive care unit by active surveillance and aggressive infection control measures, Jad Khoury, Marilyn Jones, Autumn Grim, Wm. Michael Dunne Jr., and Vicky Fraser
Mitochondrial uncoupling proteins in the central nervous system, Jeong Sook Kim-Han and Laura L. Dugan
A transcription factor for cold sensation!, Susan J. Kim, Zhican Qu, Jeffrey Milbrandt, and Min Zhuo
Pulmonary function in adolescent idiopathic scoliosis relative to the surgical procedure, Yongjung J. Kim, Lawrence G. Lenke, Keith H. Bridwell, Kyoungnam L. Kim, and Karen Steger-May
Interchromosomal segmental duplications of the pericentromeric region on the human Y chromosome, Stefan Kirsch, Birgit Weiß, Tracie L. Miner, Robert H. Waterston, Royden A. Clark, Evan E. Eichler, Claudia Münch, Werner Schempp, and Gudrun Rappold
LL5β: A regulator of postsynaptic differentiation identified in a screen for synaptically enriched transcripts at the neuromuscular junction, Masashi Kishi, Terrance T. Kummer, Stephen J. Eglen, and Joshua R. Sanes
The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKIα, Marina Kisselva, Yungfeng Feng, Michael Ward, Chunhua Song, Richard A. Anderson, and Gregory D. Longmore
M-CSF mediates TNF-induced inflammatory osteolysis, Hideki Kitaura, Ping Zhou, Hyun-Ju Kim, Deborah V. Novack, Patrick Ross, and Steven L. Teitelbaum
Errors in radiation oncology: a study in pathways and dosimetric impact, Eric E. Klein, Robert E. Drzymala, James A. Purdy, and Jeff M. Michalski
Contributions of parental alcoholism, prenatal substance exposure, and genetic transmission to child ADHD risk : A female twin study, Valerie S. Knopik, Elizabeth P. Sparrow, Pamela A F Madden, Kathleen K. Bucholz, James J. Hudziak, Wendy Reich, Wendy S. Slutske, Julia D. Grant, Tara L. McLaughlin, Alexandre Todorov, Richard D. Todd, and Andrew C. Heath
Noncapsulated Klebsiella pneumoniae bearing mannose-containing O antigens is rapidly eradicated from mouse lung and triggers cytokine production by macrophages following opsonization with surfactant protein D, Elena Kostina, Itzhak Ofek, Erika Crouch, Rotem Friedman, Lea Sirota, Gil Klinger, Hany Sahly, and Yona Keisari
Microsatellite linkage analysis, single-nucleotide polymorphisms, and haplotype associations with ECB21 in the COGA data, Aldi T. Kraja, Ingrid B. Borecki, and Michael A. Province
An evaluation of the metabolic syndrome in a large multi-ethnic study: the Family Blood Pressure Program, Aldi T. Kraja, DC Rao, Alan B. Weder, Thomas H. Mosley, Stephen T. Turner, Chao Agnes Hsiung, Thomas Quertermous, Richard Cooper, J David Curb, and Michael A. Province
Neutrophil elastase is important for PML-retinoic acid receptor α activities in early myeloid cells, Andrew A. Lane and Timothy J. Ley
Phase I evaluation of the safety and pharmacokinetics of murine-derived anticryptococcal antibody 18B7 in subjects with treated cryptococcal meningitis, Robert A. Larsen, Peter G. Pappas, John Perfect, Judith A. Aberg, Arturo Casadevall, Gretchen A. Cloud, Robert James, Scott Filler, and William E. Dismukes
The offloading model for dynein function: differential function of motor subunits, Wei-Lih Lee, Michelle A. Kaiser, and John A. Cooper
PGC-1alpha deficiency causes multi-system energy metabolic derangements: Muscle dysfunction, abnormal weight control and hepatic steatosis, Teresa C. Leone, John J. Lehman, Brian N. Finck, Paul J. Schaeffer, Adam R. Wende, Sihem Boudina, Michael Courtois, David F. Wozniak, Nandakumar Sambandam, Carlos Bernal-Mizrachi, Zhouji Chen, John O. Holloszy, Denis M. Medeiros, Robert E. Schmidt, Jeffrey E. Saffitz, E. D. Abel, Clay F. Semenkovich, and Daniel P. Kelly
Comparison of running and interrupted vesicourethral anastomoses in a porcine model, David Lieber, Veronique Tran, Jay Belani, Caroline Ames, Kevin Morissey, Yan Yan, Peter Humphrey, Ramakrishna Venkatesh, and Jaime Landman
Combining SELEX with quantitative assays to rapidly obtain accurate models of protein-DNA interactions, Jiajian Liu and Gary D. Stormo
Quantitative analysis of EGR proteins binding to DNA: Assessing additivity in both the binding site and the protein, Jiajian Liu and Gary D. Stormo
A surface groove essential for viral Bcl-2 function during chronic infection in vivo, Joy Loh, Qiulong Huang, Andrew M. Petros, David Nettesheim, Linda F. van Dyk, Lucia Labrada, Samuel H. Speck, Beth Levine, Edward T. Olejniczak, and Herbert W. Virgin IV
YB-1 is important for late-stage embryonic development, optimal cellular stress responses, and the prevention of premature senescence, Zhi Hong Lu, Jason T. Books, and Timothy J. Ley
hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation, Mary Lynch, Li Chen, Michael J. Ravitz, Sapna Mehtani, Kevin Korenblat, Michael J. Pazin, and Emmett V. Schmidt
Limitations of DSM-IV operationalizations of alcohol abuse and dependence in a sample of Australian twins, Michael T. Lynskey, Elliot C. Nelson, Rosalind J. Neuman, Kathleen K. Bucholz, Pamela A.F. Madden, Valerie S. Knopik, Wendy Slutske, John B. Whitfield, Nicholas G. Martin, and Andrew C. Heath
ACT-5 is an essential Caenorhabditis elegans actin required for intestinal microvilli formation, A. J. MacQueen, J. J. Baggett, N. Perumov, R. A. Bauer, T. Januszewski, L. Schriefer, and J. A. Waddle
Complications of fluoroscopically guided extraforaminal cervical nerve blocks: An analysis of 1036 injections, Daniel J. Ma III, Louis A. Gilula, and K. Daniel Riew
Clinical challenges and unmet needs in the management of complicated intra-abdominal infections, John E. Mazuski
A novel endogenous inhibitor of the secreted streptococcal NAD-glycohydrolase, Michael A. Meehl, Jerome S. Pinkner, Patricia J. Anderson, Scott J. Hultgren, and Michael G. Caparon
Phylogeography and population strucure of Aedes aegypti in Arizona, Samuel A. Merrill, Frank B. Ramberg, and Henry H. Hagedorn
Pseudomonas aeruginosa bloodstream infection: Importance of appropriate initial antimicrobial treatment, Scott T. Micek, Ann E. Lloyd, David J. Ritchie, Richard M. Reichley, Victoria J. Fraser, and Marin H. Kollef
Mutant kinesin-2 motor subunits increase chromosome loss, Mark S. Miller, Jessica M. Esparza, Andrew M. Lippa, Fordyce G. Lux III, Douglas G. Cole, and Susan K. Dutcher
Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species, Pat Minx, Holly Cordum, Richard Wilson, and et al
Investigating hookworm genomes by comparative analysis of two Ancylostoma species, Makedonka Mitreva, James P. McCarter, Prema Arasu, John Hawdon, John Martin, Mike Dante, Todd Wylie, Jian Xu, Jason E. Stajich, Wadim Kapulkin, Sandra W. Clifton, Robert H. Waterston, and Richard K. Wilson
Delaying the empiric treatment of Candida bloodstream infection until positive blood culture results are obtained: A potential risk factor for hospital mortality, Matthew Morrell, Victoria J. Fraser, and Marin H. Kollef
Evaluation of seaFAST, a rapid fluorescent in situ hybridization test, for detection of Helicobacter pylori and resistance to clarithromycin in paraffin-embedded biopsy sections, Julie M. Morris, Alisa L. Reasonover, Michael G. Bruce, Dana L. Bruden, Brian J. McMahon, Frank D. Sacco, Douglas E. Berg, and Alan J. Parkinson
Amprenavir and efavirenz pharmacokinetics before and after the addition of nelfinavir, indinavir, ritonavir, or saquinavir in seronegative individuals, Gene D. Morse, Susan Rosenkranz, Michael F. Para, Yoninah Segal, Robin DiFrancesco, Elizabeth Adams, Barbara Brizz, Kevin E. Yarasheski, Richard C. Reichman, and ACTG 5043 Protocol Team
Estimation of prevalence of DSM-IV and latent class-defined ADHD subtypes in a population-based sample of child and adolescent twins, Rosalind J. Neuman, Nantawat Sitdhiraksa, Wendy Reich, Ted H.-C. Ji, Cynthia A. Joyner, Ling-Wei Sun, and Richard D. Todd
Results of preoperative pulmonary function testing of adolescents with idiopathic scoliosis: A study of six hundred and thirty-one patients, Peter O. Newton, Frances D. Faro, Sohrab Gollogly, Randal R. Betz, Lawrence G. Lenke, and Thomas G. Lowe
Definition of target antigens for naturally occurring CD4+ CD25+ regulatory T cells, Hiroyoshi Nishikawa, Takuma Kato, Isao Tawara, Kanako Saito, Hiroaki Ikeda, Kagemasa Kuribayashi, Paul M. Allen, Robert D. Schreiber, Shimon Sakaguchi, Lloyd J. Old, and Hiroshi Shiku
Impact of two rounds of mass drug administration using diethylcarbamazine combined with albendazole on the prevalence of Brugia timori and of intestinal helminths on Alor Island, Indonesia, Tim Oqueka, Taniawati Supali, Is Suhariah Ismid, Purnomo, Paul Rückert, Mark Bradley, and Peter Fischer
Antimalarial activity of human immunodeficiency virus type 1 protease inhibitors, Sunil Parikh, Jiri Gut, Eva Istvan, Daniel E. Goldberg, Diane V. Havlir, and Philip J. Rosenthal
Development of adjacent-level ossification in patients with an anterior cervical plate, Jong-Beom Park, Yong-Sun Cho, and K. Daniel Riew
