The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2012
Differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals, Devon C. Crawford, Xiaoping Jiang, Amanda Taylor, Krista L. Moulder, and Steven Mennerick
Central amygdala metabotropic glutamate receptor 5 in the modulation of visceral pain, Lara W. Crock, Benedict J. Kolber, Clinton D. Morgan, Katelyn E. Sadler, Sherri K. Vogt, Michael R. Bruchas, and Robert W. Gereau IV
Metabotropic glutamate receptor 5 (mGluR5) regulates bladder nociception, Lara W. Crock, Kristina M. Stemler, David G. Song, Philip Abbosh, Sherri K. Vogt, Chang-Shen Qiu, H Henry Lai, Indira U. Mysorekar, and Robert W. Gereau IV
Novel BRAF alteration in a sporadic pilocytic astrocytoma, Sonika Dahiya, Jinsheng Yu, Aparna Kaul, Jeffrey R. Leonard, and David H. Gutmann
Missing data methods for partial correlations, Gina M. D'Angelo, Jingqin Luo, and Chengjie Xiong
Loss of ATM kinase activity leads to embryonic lethality in mice, Jeremy A. Daniel, Manuela Pellegrini, Baeck-Seung Lee, Zhi Guo, Darius Filsuf, Natalya V. Belkina, Zhongsheng You, Tanya T. Paull, Barry P. Sleckman, Lionel Feigenbaum, and André Nussenzweig
Weight perceptions and perceived risk for diabetes and heart disease among overweight and obese women, Suffolk County, New York, 2008, Susan Darlow, Melody S. Goodman, Jewel D. Stafford, Christina R. Lachance, and Kimberly A. Kaphingst
Leishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity, Maria Fernanda Laranjeira da Silva, Ricardo Andrade Zampieri, Sandra M. Muxel, Stephen M. Beverley, and Lucile M. Floeter-Winter
Antibodies against the envelope glycoprotein promote infectivity of immature Dengue Virus Serotype 2, Julia M. da Silva Voorham, Izabela A. Rodenhuis-Zybert, Nilda Vanesa Ayala Nunez, Tonya M. Colpitts, Heidi van der Ende-Metselaar, Erol Fikrig, Michael S. Diamond, Jan Wilschut, and Jolanda M. Smit
Educating medical students in musculoskeletal surgery and medicine: How to get a course up and running at your institution: AOA Critical Issues, Charles S. Day, Joseph Bernstein, and Martin I. Boyer
Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions, Keith F. Decker, Dali Zheng, Yuhong He, Tamara Bowman, John R. Edwards, and Li Jia
MuSiC: Identifying mutational significance in cancer genomes, Nathan D. Dees, Qunyuan Zhang, Cyriac Kandoth, Michael C. Wendl, William Schierding, Daniel C. Kobolt, Thomas B. Mooney, Matthew B. Callaway, David Dooling, Elaine R. Mardis, Richard K. Wilson, and Li Ding
Recent progress in West Nile virus diagnosis and vaccination, Marina De Filette, Sebastian Ulbert, Mike Diamond, and Niek N. Sanders
Social cognition in Williams syndrome: Relations between performance on the social attribution task and cognitive and behavioral characteristics, Faye van der Fluit, Michael S. Gaffrey, and Bonita P. Klein-Tasman
Amacrine cells: Seeing the forest and the trees, Jeffrey S. Diamond and Peter D. Lukasiewicz
The AMPK β2 subunit is required for energy homeostasis during metabolic stress, Biplab Diasgupta, Jeong Sun Ju, Yo Sasaki, Xiaona Liu, Su-Ryun Jung, Kazuhiko Higashida, Diana Lindquist, and Jeffrey Milbrandt
A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis, John F. DiPersio and et al
Ultrastructural studies in APP/PS1 mice expressing human ApoE isoforms: implications for Alzheimer’s disease, Krikor Dirkranian, Jungsu Kim, Floy R. Stewart, Marilyn A. Levy, and David M. Holtzman
Guidelines for the use and interpretation of assays for monitoring autophagy, Abhinav Diwan, Seungmin Hwang, Indira Mysorekar, William A. Weiss, and et al
Retinal horizontal cells lacking Rb1 sustain persistent DNA damage and survive as polyploid giant cells, Stacy L. Donovan and Joseph C. Corbo
ALIX binds a YPX3L motif of the GPCR PAR1 and mediates ubiquitin-independent ESCRT-III/MVB sorting, Michael R. Dores, Buxin Chen, Huilan Lin, May M. Paing, William A. Montagne, Timo Meerlo, and JoAnn Trejo
AP-3 regulates PAR1 ubiquitin-independent MVB/lysosomal sorting via an ALIX-mediated pathway, Michael R. Dores, May M. Paing, William A. Montagne, Adriano Marchese, JoAnn Trejo, and Huilan Lin
Mouse transgenesis in a single locus with independent regulation for multiple fluorophores, Joseph D. Dougherty, Juliet Zhang, Huifen Feng, Shiaoching Gong, and Nathaniel Heintz
Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells, Barbara Drobits, Martin Holcmann, Nicole Amberg, Melissa Swiecki, Roland Grundtner, Martina Hammer, Marco Colonna, and Maria Sibilia
Implementing automated surveillance for tracking Clostridium difficile infection at multiple healthcare facilities, Erik R. Dubberke, Humaa A. Nyazee, Deborah S. Yokoe, Jeanmarie Mayer, Kurt B. Stevenson, Julie E. Mangino, Yosef M. Khan, Victoria J. Fraser, and Centers for Disease Control and Prevention Epicenter Program
Should one measure balance or gait to best predict falls among people with Parkinson disease?, Ryan P. Duncan and Gammon M. Earhart
Accuracy of fall prediction in Parkinson disease: six-month and 12-month prospective analyses, Ryan P. Duncan, Abigail L. Leddy, James T. Cavanaugh, Leland E. Dibble, Terry D. Ellis, Matthew P. Ford, K. B. Foreman, and Gammon M. Earhart
Whole-genome sequencing to identify mutants and polymorphisms in Chlamydomonas reinhardtii, Susan K. Dutcher, Linya Li, Huawen Lin, Leslie Meyer, Thomas H. Giddings Jr., Alan L. Kwan, and Brian L. Lewis
The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila, Laura B. Duvall and Paul H. Taghert
Attention deficit hyperactivity disorder in Australian adults: Prevalence, persistence, conduct problems and disadvantage, Jane L. Ebejer, Sarah E. Medland, Julius van der Werf, Cedric Gondro, Anjali K. Henders, Michael Lynskey, Nicholas G. Martin, and David L. Duffy
AKT1 loss correlates with episomal HPV16 in vulval intraepithelial neoplasia, Arucha L. Ekeowa-Anderson, Karin J. Purdie, Karen Gibbon, Carolyn R. Byrne, Jeffrey M. Arbeit, Catherine A. Harwood, and Ryan F. L. O'Shaughnessy
Nature and function of insulator protein binding sites in the Drosophila genome, Sarah C. R. Elgin and et al
PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers, Matthew J. Ellis and et al
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor, Bart Everts, Leonie Hussaarts, Nicole N. Driessen, Moniek H.J. Meevissen, Gabriele Schramm, Alwin J. van der Ham, Barbara van der Hoeven, Thomas Scholzen, Sven Burgdorf, Markus Mohrs, Edward J. Pearce, Cornelis H. Hokke, Helmut Haas, Hermelijn H. Smits, and Maria Yazdanbakhsh
IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease, Keke C. Fairfax, Eyal Amiel, Irah L. King, Tori C. Freitas, Markus Mohrs, and Edward J. Pearce
Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a, Anthony R. Fehr, Nathaniel C. Gualberto, John Paul Savaryn, Scott S. Terhune, and Dong Yu
Co-survival of the fittest few: Mosaic amplification of receptor tyrosine kinases in glioblastoma, Chen Feng and Li Ding
A dual role of BRCA1 in two distinct homologous recombination mediated repair in response to replication arrest, Zhihui Feng and Junran Zhang
Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis, Volker Fensterl, Jaime L. Wetzel, Srividya Ramachandran, Tomoaki Ogino, Stephen A. Stohlman, Cornelia C. Bergmann, Michael S. Diamond, Herbert W. Virgin, and Ganes C. Sen
Comparison of accelerated partial breast irradiation via multicatheter interstitial brachytherapy versus whole breast radiation, Daniel J. Ferraro, Adam A. Garsa, Todd A. DeWees, Julie A. Margenthaler, Michael Naughton, Rebecca Aft, William E. Gillanders, Timothy Eberlein, Melissa A. Matesa, and Imran Zoberi
Unproductive alternative splicing and nonsense mRNAs: A widespread phenomenon among plant circadian clock genes, Sergei A. Filichkin and Todd C. Mockler
A multicenter evaluation of diagnostic tools to define endpoints for programs to eliminate bancroftian filariasis, Peter U. Fischer, Ramakrishna U. Rao, and et al
The structure of the PapD-PapGII pilin complex reveals an open and flexible p5 pocket, Bradley Ford, Denis Verger, Karen Dodson, Ender Volkan, Maria Kostakioti, Jennifer Elam, Jerome Pinkner, Gabriel Waksman, and Scott Hultgren
Reply to Herigon and Newland, Stephanie A. Fritz, Bernard C. Camins, Jonathan Dukes, and Gregory A. Storch
Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: A case report, Ryan K. Funk, Daniel J. Ferraro, Richard J. Perrin, Kyle M. Hurth, John J. Stephens, David B. Mansur, Michael R. Chicoine, Joseph R. Simpson, and Jerry J. Jaboin
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104), Thomas F. Gajewski, April KS Salama, Donna Niedzwiecki, Jeffrey Johnson, Gerald Linette, Cynthia Bucher, Michelle A. Blaskovich, Said M. Sebti, Frank Haluska, and Cancer and Leukemia Group B
Structural features based genome-wide characterization and prediction of nucleosome organization, Yanglan Gan, Jihong Guan, Shuigeng Zhou, and Weixiong Zhang
The effect of changes in intraocular pressure on the risk of primary open-angle glaucoma in patients with ocular hypertension: An application of latent class analysis, Feng Gao, J. P. Miller, Stefano Miglior, Julia A. Beiser, Valter Torri, Michael A. Kass, and Mae E. Gordon
Genome-wide association and functional follow-up reveals new loci for kidney function, Xiaoyi Gao, Mary Feitosa, Michael Province, Shamika Ketkar, Ingrid Borecki, and et al.
Partner randomized controlled trial: Study protocol and coaching intervention, Jane M. Garbutt, Gabrielle Highstein, Yan Yan, and Robert C. Strunk
Time of day regulates subcellular trafficking, tripartite synaptic localization, and polyadenylation of the astrocytic Fabp7 mRNA, Jason R. Gerstner, William M. Vanderheyden, Timothy LaVaute, Cara J. Westmark, Labib Rouhana, Allan I. Pack, Marv Wickens, and Charles F. Landry
A glycosylphosphatidylinositol anchor is required for membrane localization but dispensable for cell wall association of chitin deacetylase 2 in Cryptococcus neoformans, Nicole M. Gilbert, Lorina G. Baker, Charles A. Specht, and Jennifer K. Lodge
Snail promotes the cell-autonomous generation of Flk1 + endothelial cells through the repression of the microRNA-200 family, Jennider G. Gill, Ellen M. Langer, R Coleman Lindsley, Mi Cai, Theresa L. Murphy, and Kenneth M. Murphy
BNip3 regulates mitochondrial function and lipid metabolism in the liver, Danielle Glick, Wenshuo Zhang, Michelle Beaton, Glenn Marsboom, Michaela Gruber, M. Celeste Simon, John Hart, Gerald W. Dorn II, Matthew J. Brady, and Kay F. Macleod
Isolated short femur length on second-trimester sonography: A marker for fetal growth restriction and other adverse perinatal outcomes, Katherine R. Goetzinger, Alison G. Cahill, George A. Macones, and Anthony O. Odibo
A case study for large-scale human microbiome analysis using JCVI’s Metagenomics Reports (METAREP), Johannes Goll, Mathangi Thiagarajan, Sahar Abubucker, Curtis Huttenhower, Shibu Yooseph, and Barbara A. Methe
Quantitative assessment of participant knowledge and evaluation of participant satisfaction in the CARES training program, Melody S. Goodman, Xuemei Si, Jewel D. Stafford, Adesuwa Obasohan, and Cheryl Mchunguzi
Analysis of Gga null mice demonstrates a non-redundant role for mammalian GGA2 during development, Jennifer Govero, Balraj Doray, Hongdong Bai, and Stuart Kornfeld
RIM promotes calcium channel accumulation at active zones of the Drosophila neuromuscular junction, Ethan R. Graf, Vera Valakh, Christina M. Wright, Chunlai Wu, Zhihua Liu, Yong Q. Zhang, and Aaron DiAntonio
I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity, Daniel Granados-Fuentes, Aaron J. Norris, Yarimar Carrasquillo, Jeanne M. Nerbonne, and Erik D. Herzog
Attempted endoscopic closure of a pancreaticocolonic fistula with an over-the-scope clip, Darrell M. Gray II and Daniel K. Mullady
FGFR1 amplifi cation and the progression of non-invasive to invasive breast cancer, Alejandro A. Gru and D. Craig Allred
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice, Pascale S. Guiton, Corinne K. Cusumano, Kimberly A. Kline, Karen W. Dodson, Zhenfu Han, James W. Janetka, Jeffrey P. Henderson, Michael G. Caparon, and Scott J. Hultgren
Tetraspanin CO-029 inhibits colorectal cancer cell movement by deregulating cell-matrix and cell-cell adhesions, Qiusha Guo, Bing Xia, Feng Zhang, Mekel M. Richardson, Minghao Li, Julian S. Zhang, Feng Chen, and Xin A. Zhang
Neurofibromatosis type 1: Modeling CNS dysfunction, David H. Gutmann, Luis F. Parada, Alcino J. Silva, and Nancy Ratner
Causal links between dorsal medial superior temporal area neurons and multisensory heading perception, Yong Gu, Gregory C. DeAngelis, and Dora E. Angelaki
Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors, Maria Hadjifrangiskou, Alice P. Gu, Jerome S. Pinkner, Maria Kostakioti, Ellisa W. Zhang, Sarah E. Greene, and Scott J. Hultgren
What does it take to stick around?: Molecular insights into biofilm formation by uropathogenic Escherichia coli, Maria Hadjifrangiskou and Scott J. Hultgren
Prevention of musculoskeletal disorders in workers: Classification and health surveillance – statements of the Scientific Committee on Musculoskeletal Disorders of the International Commission on Occupational Health, Mats Hagberg, Francesco Saverio Violante, Roberta Bonfiglioli, Alexis Descatha, Judith Gold, Brad Evanoff, and Judith K. Sluiter
Sodium-activated potassium channels are functionally coupled to persistent sodium currents, Travis A. Hage and Lawrence Salkoff
Development of a novel xenotransplantation strategy for treatment of diabetes mellitus in rat hosts and translation to non-human primates, Marc R. Hammerman
Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways, Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J. Edenberg, Andrew Heath, Nicholas G. Martin, Michele L. Pergadia, Grant Montgomery, Andrew Schrage, Laura J. Bierut, Pamela F. Madden, and Alison M. Goate
Intermediate outcomes following percutaneous fixation of proximal humeral fractures, Alicia K. Harrison, Konrad I. Gruson, Benjamin Zmistowski, Jay Keener, Leesa Galatz, Gerald Williams, Bradford O. Parsons, and Evan L. Flatgow
Role of the polarity protein Scribble for podocyte differentiation and maintenance, Bjorn Hartleben, Eugen Widmeier, Nicola Wanner, Miriam Schmidts, Sung Tae Kim, Lisa Schneider, Britta Mayer, Dontscho Kerjaschki, Jeffrey H. Miner, Gerd Walz, and Tobias B. Huber
Leishmania RNA virus: When the host pays the toll, Mary-Anne Hartley, Catherine Ronet, Haroun Zangger, Stephen M. Beverley, and Nicolas Fasel
Apolipoprotein e, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide, Tadafumi Hashimoto, Alberto Serrano-Pozo, Yukiko Hori, Kenneth W. Adams, Shuko Takeda, Adrian Olaf Banerji, Akinori Mitani, Daniel Joyer, Diana H. Thyssen, Brian J. Bacskai, Matthew P. Frosch, Tara L. Spires-Jones, Mary Beth Finn, David M. Holtzman, and Bradley T. Hyman
Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne M. Fagan, David M. Holtzman, Randall Bateman, Hamid R. Sohrabi, Ralph N. Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki, and Japanese Alzheimer's Disease Neuroimaging Initiative
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales, A. C. Heath, P. A. F. Madden, and et al
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA, Andrew C. Heath, Pamela A. F. Madden, and et al
Changing epidemiology of methicillin-resistant Staphylococcus aureus colonization in paediatric intensive-care units, C. R. Hermos, T. J. Sandora, L. E. Williams, N. Mosammaparast, and A. J. McAdam
Early brain vulnerability in Wolfram syndrome, Tamara Hershey, Heather M. Lugar, Joshua S. Shimony, Jerrel Rutlin, Jonathan M. Koller, Dana C. Perantie, Alex R. Paciorkowski, Sarah A. Eisenstein, M. Alan Permutt, and Washington University Wolfram Study Group
Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease, Xu He, Thomas Haselhorst, Mark von Itzstein, Daniel Kolarich, Nicolle H. Packer, Tracey M. Gloster, David J. Vocadlo, Lorne A. Clarke, Yi Qian, and Allison R. Kermode
Validation of self-reported measures in health disparities research, Bertha Hidalgo and Melody Goodman
The impact of mild stroke on participation in physical fitness activities, Mary Hildebrand, Megan Brewer, and Timothy Wolf
Lysosomal membrane permeabilization is an early event in sigma-2 receptor ligand mediated cell death in pancreatic cancer, John R. Hornick, Suwanna Vangveravong, Dirk Spitzer, Carmen Abate, Francesco Berardi, Peter Goedegebuure, Robert H. Mach, and William G. Hawkins
Lecture: New light on the role of claudins in the kidney, Jianghui Hou
Expression of the transient receptor potential channels TRPV1, TRPA1 and TRPM8 in mouse trigeminal primary afferent neurons innervating the dura, Dongyue Huang, Shuyang Li, Ajay Dhaka, Gina M. Story, and Yu-Qing Cao
Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni, Stanley Ching-Cheng Huang, Tori C. Freitas, Eyal Amiel, Bart Everts, Erika L. Pearce, James B. Lok, and Edward J. Pearce
Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal, Sung-Ho Huh, Jennifer Jones, Mark E. Warchol, and David M. Ornitz
Clinical application of heart rate variability after acute myocardial infarction, Heikki V. Huikuri and Phyllis K. Stein
Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis, Michelle A. Hurchla and Katherine N. Weilbaecher
A core human microbiome as viewed through 16S rRNA sequence clusters, Susan M. Huse, Yuzhen Ye, Yanjiao Zhou, and Anthony A. Fodor
Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes, Katherine L. Hussmann, Melanie A. Samuel, Kwang S. Kim, Michael S. Diamond, and Brenda L. Fredericksen
Adjuvant chemotherapy for breast cancer in patients with schizophrenia, Mark Hwang, Mishel Farasatpour, Campbell D. Williams, Julie A. Margenthaler, Katherine S. Virgo, and Frank E. Johnson
The mode of retinal presynaptic inhibition switches with light intensity, Tomomi Ichinose and Peter D. Lukasiewicz
Fast, sensitive discovery of conserved genome-wide motifs, NNamdi E. Ihuegbu, Gary D. Stormo, and Jeremy Buhler
Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system, Jamie M. Ireland and Emil R. Unanue
c-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton, Takashi Izawa, Wei Zou, Jean C. Chappel, Jason W. Ashley, Xu Feng, and Steven L. Teitelbaum
A survey tool for measuring evidence-based decision making capacity in public health agencies, Julie A. Jacobs, Paula F. Clayton, Cassandra Dove, Tanya Funchess, Ellen Jones, Ghazala Perveen, Brandon Skidmore, Victor Sutton, Sarah Worthington, Elizabeth A. Baker, Anjali D. Deshpande, and Ross C. Brownson
Tools for implementing an evidence-based approach in public health practice, Julie A. Jacobs, Ellen Jones, Barbara A. Gabella, Bonnie Spring, and Ross C. Brownson
