The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2009

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In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from nontumorigenic astrocytes and brain tumours, Michael A. Kiebish, Xianlin Han, Hua Cheng, and Thomas N. Seyfried

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Shoulder strength in asymptomatic individuals with intact compared with torn rotator cuffs, H. Mike Kim, Sharlene A. Teefey, Ari Zelig, Leesa M. Galatz, Jay D. Keener, and Ken Yamaguchi

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Impact speed does not determine severity of spinal cord injury in mice with fixed impact displacement, Joong Hee Kim, Tsang-Wei Tu, Philip V. Bayly, and Sheng-Kwei Song

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Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis, Kimberly Kline, Andrew L. Kau, Swaine L. Chen, Adeline Lim, Jerome S. Pinkner, Jason Rosch, Sreedhar R. Nallapareddy, Barbara E. Murray, Birgitta Henriques-Normark, Wandy Beatty, Michael G. Caparon, and Scott J. Hultgren

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Evidence-based approach for interpretation of Epstein-Barr virus serological patterns, J. S. Klutts, B. A. Ford, N. R. Perez, and A. M. Gronowski

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The Genetic Analysis Workshop 16 Problem 3: Simulation of heritable longitudinal cardiovascular phenotypes based on actual genome-wide single-nucleotide polymorphisms in the Framingham Heart Study, Aldi T. Kraja, Robert Culverhouse, E Warwick Daw, Jun Wu, Andrew Van Brunt, Michael A. Province, and Ingrid B. Borecki

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Avian cone photoreceptors tile the retina as five independent, self-organizing mosaics, Yoseph A. Kram, Stephanie Mantey, and Joseph C. Corbo

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Externalizing disorders: Cluster 5 of the proposed meta-structure for DSM-V and ICD-11, R. F. Krueger and S. C. South

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Improving Gene-finding in Chlamydomonas reinhardtii: GreenGenie2, Alan L. Kwan, Linya Li, David C. Kulp, Susan K. Dutcher, and Gary D. Stormo

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A novel autotransporter adhesin is required for efficient colonization during bubonic plague, Matthew B. Lawrenz, Jonathan D. Lenz, and Virginia L. Miller

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Genetic influences on individual differences in nicotine glucuronidation, Christina N. Lessov-Schlaggar, Neal L. Benowitz, Peyton Jacob III, and Gary E. Swan

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Distinct roles for CARMIL isoforms in cell migration, Yun Liang, Hanspeter Niederstrasser, Marc Edwards, Charles E. Jackson, and John A. Cooper

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Streptolysin S inhibits neutrophil recruitment during the early stages of Streptococcus pyogenes infection, Ada Lin, Jennifer A. Loughman, Bernd H. Zinselmeyer, Mark J. Miller, and Michael G. Caparon

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KSR1 modulates the sensitivity of mitogen-activated protein kinase pathway activation in T cells without altering fundamental system outputs, Joseph Lin, Angus Harding, Emanuele Giurisato, and Andrey S. Shaw

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Leishmania major phosphoglycans influence the host early immune response by modulating dendritic cell functions, Dong Liu, Chahnaz Kebaier, Althea A. Capul, Stephen M. Beverley, Phillip Scott, and Jude E. Uzonna

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MLL fusions: Pathways to leukemia, Han Liu, Emily H.Y. Cheng, and James J.D. Hsieh

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LRP1 shedding in human brain: Roles of ADAM10 and ADAM17, Qiang Liu, Juan Zhang, Hien Tran, Marcel M. Verbeek, Karina Reiss, Steven Estus, and Guojun Bu

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Information criterion-based clustering with order-restricted candidate profiles in short time-course microarray experiments, Tianqing Liu, Nan Lin, Ningzhong Shi, and Baoxue Zhang

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Bos taurus genome assembly, Yue Liu, Xiang Qin, Xing-Zhi Henry Song, Huaiyang Jiang, Yufeng Shen, K James Durbin, Sigbjørn Lien, Matthew Peter Kent, Marte Sodeland, Yanru Ren, Lan Zhang, Erica Sodergren, Paul Havlak, Kim C. Worley, George M. Weinstock, and Richard A. Gibbs

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Rapid identification of homologous recombinants and determination of gene copy number with reference/query pyrosequencing (RQPS), Zhenyi Liu, Anna C. Obenauf, Michael R. Speicher, and Raphael Kopan

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Serum human chorionic gonadotropin concentrations greater than 400,000 IU/L are invariably associated with suppressed serum thyrotropin concentrations, Christina M. Lockwood, David G. Grenache, and Ann M. Gronowski

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Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant, M Paula Longhi, Christine Trumpfheller, Juliana Idoyaga, Marina Caskey, Ines Matos, Courtney Kluger, Andres M. Salazar, Marco Colonna, and Ralph M. Steinman

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Divergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/insulin/IGF-receptor pathway, Meghann E. Mabon, Barbara A. Scott, and C. Michael Crowder

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Flexible Mx specification of various extended twin kinship designs, Hermine H. Maes, Michael C. Neale, Sarah E. Medland, Matthew C. Keller, Nicholas G. Martin, Andrew C. Heath, and Lindon J. Eaves

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Classification and developmental biology of congenital anomalies of the hand and upper extremity, Paul R. Manske and Kerby C. Oberg

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Proteomic analyses of native brain KV4.2 channel complexes, Celine Marionneau, Richard D. LeDuc, Henry W. Rohrs, Andrew J. Link, R. Reid Townsend, and Jeanne M. Nerbonne

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Between community and hospital: Healthcare-associated gram-negative bacteremia among hospitalized patients, Jonas Marschall, Victoria J. Fraser, Joshua Doherty, and David K. Warren

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Presence of the KPC carbapenemase gene in enterobacteriaceae causing bacteremia and its correlation with in vitro carbapenem susceptibility, Jonas Marschall, Robert J. Tibbetts, W. Michael Dunne Jr., Jonathan G. Frye, Victoria J. Fraser, and David K. Warren

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Nematode.net update 2008: Improvements enabling more efficient data mining and comparative nematode genomics, John Martin, Sahar Abubucker, Todd Wylie, Yong Yin, Zhengyuan Wang, and Makedonka Mitreva

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Extending the duration of response in chronic myelogenous leukemia: Targeted therapy with sequential tyrosine kinase inhibitors, Michael G. Martin, John F. DiPersio, and Geoffrey L. Uy

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Novel features of the polysaccharide-digesting gliding bacterium Flavobacterium johnsoniae as revealed by genome sequence analysis, Mark J. McBride, Gary Xie, Eric C. Martens, Alla Lapidus, Bernard Henrissat, Ryan G. Rhodes, Eugene Goltsman, Wei Wang, Jian Xu, David W. Hunnicutt, Andrew M. Staroscik, Timothy R. Hoover, Yi-Qiang Cheng, and Jennifer L. Stein

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Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells, Stephen McCartney, William Vermi, Susan Gilfillan, Marina Cella, Theresa L. Murphy, Robert D. Schreiber, Kenneth M. Murphy, and Marco Colonna

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The efficiency and fidelity of 8-oxo-guanine bypass by DNA polymerases delta and eta, Scott D. McCulloch, Robert J. Kokoska, Parie Garg, Peter M. Burgers, and Thomas A. Kunkel

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A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP, Sarah M. McWhirter, Roman Barbalat, Kathryn M. Monroe, Mary F. Fontana, Mamoru Hyodo, Nathalie T. Joncker, Ken J. Ishii, Shizuo Akira, Marco Colonna, Zhijian J. Chen, Katherine A. Fitzgerald, Yoshihiro Hayakawa, and Russell E. Vance

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Molecular profiling reveals diversity of stress signal transduction cascades in highly penetrant Alzheimer’s disease human skin fibroblasts, Graziella Mendonsa, Justyna Dobrowolska, Angela Lin, Pooja Vijairania, Y.-J. I. Jong, and Nancy L. Baenziger

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High-resolution sonography of the normal extrapelvic vas deferens, William D. Middleton, Nirvikar Dahiya, Cathy K. Naughton, Sharlene A. Teefey, and Cary A. Siegel

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Vav links the T cell antigen receptor to the actin cytoskeleton and T cell activation independently of intrinsic guanine nucleotide exchange activity, Ana V. Miletic, Daniel B. Graham, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J. Hamann, Saso Cemerski, Tracie Kloeppel, Daniel D. Billadeau, Osami Kanagawa, Makio Tokunaga, and Wojciech Swat

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Phasic and tonic modes of depolarization-exocytosis coupling in β-cells of porcine islets of Langerhans, Stanley Misler, Amelia M. Silva, David Barnett, and Adam S. Dickey

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Electrical activity and exocytotic correlates of biphasic insulin secretion from β-cells of canine islets of Langerhans, Stanley Misler, Zhuan Zhou, Adam S. Dickey, Amelia M. Silva, David M. Pressel, and David W. Barnett

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The value of intraoperative gram stain in revision total knee arthroplasty, Patrick M. Morgan, Peter Sharkey, Elie Ghanem, Javad Parvizi, John C. Clohisy, R. Stephen J. Burnett, and Robert L. Barrack

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Insulin resistance heralds positive cultures after severe injury, Nathan T. Mowery, Randy J. Carnevale, Oliver L. Gunter, Patrick R. Norris, Lesly A. Dossett, Marcus J. Dortch, John A. Morris Jr, and Addison K. May

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Detection and quantification of hepatitis C virus (HCV) by MultiCode-RTX real-time PCR targeting the HCV 3′ untranslated region, Elizabeth K. Mulligan, J. J. Germer, Max Q. Arens, Krista L. D'Amore, Adrian Di Bisceglie, Nathan A. Ledeboer, Michael J. Moser, Andrew C. Newman, Andy K. O'Guin, Paul D. Olivo, Diane S. Podzorski, Kimberly A. Vaughan, Joseph D. Yao, Slava A. Elagin, and Scott C. Johnson

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A Case Report Demonstrating Unambiguous Clinical Utility of Pet/CT Scanning in Recurrent Ovarian Cancer, David Mutch and Maurie Markman

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Performance evaluation of the VersaTREK blood culture system for quality control testing of platelet units, Suparna Nanua, Carol Weber, Liz Isgriggs, and W. Michael Dunne Jr.

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Molecular diversity of the antimicrobial domain of beta-defensin 3 and homologous peptides, Gerardo M. Nava, Magdalena Escorcia, and M. Pilar Castañeda

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Supplementary feeding with either ready-to-use fortified spread or corn-soy blend in wasted adults starting antiretroviral therapy in Malawi: Randomised, investigator blinded, controlled trial, MacDonald J. Ndekha, Joep J.G van Oosterhout, Eduard E. Zijlstra, Micah Manary, Haroon Saloojee, and Mark J. Manary

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TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria, Elsa-Noah N'Diaye, Catherine S. Branda, Steven S. Branda, Lisette Nevarez, Marco Colonna, Clifford Lowell, Jessica A. Hamerman, and William E. Seaman

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Serologic evidence of frequent human infection with WU and KI polyomaviruses, Nang L. Nguyen, Binh-Minh Le, and David Wang

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The association between increased use of labor induction and reduced rate of cesarean delivery, James M. Nicholson, Peter Cronholm, Lisa C. Kellar, Morghan H. Stenson, and George A. Macones

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OmpA of uropathogenic Escherichia coli promotes postinvasion pathogenesis of cystitis, Tracy F. Nicholson, Kristin M. Watts, and David A. Hunstad

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Phase II study of continuous daily sunitinib dosing in patients with previously treated advanced non-small cell lung cancer, Silvia Novello, Giorgio V. Scagliotti, Rafael C. Rosell, Mark A. Socinski, Julie R. Brahmer, James N. Atkins, Cinta Palleres, Russell E. Burgess, Lesley Tye, Paulina Selaru, Erjian Wang, Richard Chao, and Ramaswamy Govindan

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Tregs control the development of symptomatic West Nile virus infection in humans and mice, Katie M. O'Brien, Whitney E. Purtha, Michael S. Diamond, Marion C. Lanteri, Mark J. Cameron, Jennifer M. Lund, Rachel E. Owen, John W. Heitman, Brian Custer, Dale F. Hirschkorn, Leslie H. Tobler, Nancy Kiely, Harry E. Prince, Lishomwa C. Ndhlovu, Douglas F. Nixon, and et. al

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Developing a risk stratification model for surgical site infection after abdominal hysterectomy, Margaret A. Olsen, James Higham-Kessler, Deborah S. Yokoe, Anne M. Butler, Johanna Vostok, Kurt B. Stevenson, Yosef Khan, and Victoria J. Fraser

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Assessment of personaility dimensions in children and adolescents with bipolar disorder using the junior temperament and character inventory, Rene L. Olvera, Manoela Fonseca, Sheila C. Caetano, John P. Hatch, Kristina Hunter, Mark Nicoletti, Steven R. Pliszka, C. Robert Cloninger, and Jair C. Soares

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Chromatin remodeling finds its place in the DNA double-strand break response, Tej K. Pandita and Christine Richardson

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Longitudinal trends in the association of metabolic syndrome with 550 k single-nucleotide polymorphisms in the Framingham Heart Study, Yong-Moon Park, Michael A. Province, Xiaoyi Gao, Mary Feitosa, Jun Wu, Duanduan Ma, DC Rao, and Aldi T. Kraja

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Unusual composition of a yeast chromosome arm is associated with its delayed replication, Célia Payen, Gilles Fischer, Christian Marck, Caroline Proux, David James Sherman, Jean-Yves Coppée, Mark Johnston, Bernard Dujon, and Cécile Neuvéglise

High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples, Jacqueline E. Payton, Nicole R. Grieselhuber, Li-Wei Chang, Mark Murakami, Gary K. Geiss, Daniel C. Link, Rakesh Nagarajan, Mark A. Watson, and Timothy J. Ley

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Retention of a well-fixed acetabular component in the setting of massive acetabular osteolysis and pelvic discontinuity: A case report, Murat Pekmezci, James Keeney, Amanda Schutz, and John C. Clohisy

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Evolution of a bacterial regulon controlling virulence and Mg(2+) homeostasis, J. Christian Perez, Dongwoo Shin, Igor Zwir, Tammy Latifi, Tricia J. Hadley, and Eduardo A. Groisman

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Potentially pathogenic bacteria in shower water and air of a stem cell transplant unit, Sarah D. Perkins, Jennie Mayfield, Victoria Fraser, and Largus T. Angenent

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The effects of tail biopsy for genotyping on behavioral responses to nociceptive stimuli, Maria Elena P. Morales and Robert W. Gereau IV

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Host-dependent Lewis (Le) antigen expression in Helicobacter pylori cells recovered from Leb-transgenic mice, Mary Ann Pohl, Judith Romero-Gallo, Janaki L. Guruge, Doris B. Tse, Jeffrey I. Gordon, and Martin J. Blaser

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Biomechanics of running indicates endothermy in bipedal dinosaurs, Herman Pontzer, Vivian Allen, and John R. Hutchinson

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Profile analysis and prediction of tissue-specific CpG island methylation classes, Christopher Previti, Oscar Harari, Igor Zwir, and Coral del Val

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A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale, Joseph L. Price, David C. Van Essen, and et al.

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Yersinia pestis can reside in autophagosomes and avoid xenophagy in murine macrophages by preventing vacuole acidification, Celine Pujol, Kathryn A. Klein, Galina A. Romanov, Lance E. Palmer, Carol Cirota, Zijiang Zhao, and James B. Bliska

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Suggestion for linkage of chromosome 1p35.2 and 3q28 to plasma adiponectin concentrations in the GOLDN Study, Laura J. Rasmussen-Torvik, James S. Pankow, James M. Peacock, Ingrid B. Borecki, James E. Hixson, Michael Y. Tsai, Edmond K. Kabagambe, and Donna K. Arnett

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Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma, Lee Ratner, William Harrington, Xuan Feng, Christian Grant, Steve Jacobson, Ariela Noy, Joseph Sparano, Jeannette Lee, Richard Ambinder, Nancy Campbell, and Michael Lairmore

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T-cell activation promotes tumorigenesis in inflammation-associated cancer, Dan Rauch, Shimon Gross, John Harding, Sirosh Bokhari, Stefan Niewiesk, Michael Lairmore, David Piwnica-Worms, and Lee Ratner

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Bringing KASH under the SUN: The many faces of nucleo-cytoskeletal connections, David Razafsky and Didier Hodzic

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Cloning, characterization and expression analysis of porcine microRNAs, Alavala Matta Reddy, Yun Zheng, Guru Jagadeeswaran, Simone L. Macmil, Wiley B. Graham, Bruce A. Roe, Udaya Desilva, Weixiong Zhang, and Ramanjulu Sunkar

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Inclusion biogenesis and reactivation of persistent Chlamydia trachomatis requires host cell sphingolipid biosynthesis, D. Kesley Robertson, Ling Gu, Regina K. Rowe, and Wandy L. Beatty

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The value of avian genomics to the conservation of wildlife, Michael N. Romanov, Elaina M. Tuttle, Marlys L. Houck, William S. Modi, Leona G. Chemnick, Marisa L. Korody, Emily M. Stremel Mork, Christie A. Otten, Tanya Renner, Kenneth C. Jones, Sugandha Dandekar, Jeanette C. Papp, Yang Da, NISC Comparative Sequencing Program, Eric D. Green, Vincent Magrini, Matthew T. Hickenbotham, Jarret Glasscock, Sean McGrath, Elaine R. Mardis, and Oliver A. Ryder

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Evidence for high bi-allelic expression of activating Ly49 receptors, Arefeh Rouhi, C. B. Lai, Tammy P. Cheng, Fumio Takei, Wayne M. Yokoyama, and Dixie L. Mager

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An ensemble learning approach to reverse-engineering transcriptional regulatory networks from time-series gene expression data, Jianhua Ruan, Youping Deng, Edward J. Perkins, and Weixiong Zhang

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Supplementing high-density SNP microarrays for additional coverage of disease-related genes: Addiction as a paradigm, Scott F. Saccone, Laura J. Bierut, Elissa J. Chesler, Peter W. Kalivas, Caryn Lerman, Nancy L. Saccone, George R. Uhl, Chuan-Yun Li, Vivek M. Philip, Howard J. Edenberg, Stephen T. Sherry, Michael Feolo, Robert K. Moyzis, and Joni L. Rutter

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HIV-1 CRF 02 AG polymerase genes in Southern Ghana are mosaics of different 02 AG strains and the protease gene cannot infer subtypes, Kwamena W. Sagoe, Magda Dwidar, Theophilus K. Adiku, and Max Q. Arens

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The Bacillus anthracis protein MprF is required for synthesis of lysylphosphatidylglycerols and for resistance to cationic antimicrobial peptides, Shalaka Samant, Fong-Fu Hsu, Alexander A. Neyfakh, and Hyunwoo Lee

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Comparison of arthroscopic and open treatment of septic arthritis of the wrist, Douglas M. Sammer and Alexander Y. Shin

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Multiple hereditary exostosis, EXT genes, and skeletal development, Linda J. Sandell

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Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins, Cheri A. Schaaf, Ziva Misulovin, Gurmukh Sahota, Akbar M. Siddiqui, Yuri B. Schwartz, Tatyana G. Kahn, Vincenzo Pirrotta, Maria Gause, and Dale Dorsett

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A phase 2 study of vorinostat in acute myeloid leukemia, Eric W. Schaefer, Arturo Loaiza-Bonilla, Mark Juckett, John F. DiPersio, Vivek Roy, James Slack, Wenting Wu, Kristina Laumann, Igor Espinoza-Delgado, and Steven D. Gore

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High harvest yield, high expansion, and phenotype stability of CD146 mesenchymal stromal cells from whole primitive human umbilical cord tissue, Rebecca C. Schugar, Steven M. Chirieleison, Kristin E. Wescoe, Benjamin T. Schmidt, Yuko Askew, Jordan J. Nance, Joshua M. Evron, Bruno Peault, and Bridget M. Deasy

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Routine screening for depression: Identifying a challenge for successful HIV care, E Shacham, D Nurutdinova, V Satyanarayana, K Stamm, and E. T. Overton

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Cervical spine motion during extrication: A pilot study, Jeffrey S. Shafer and Rosanne S. Naunheim

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RNA-interference knockdown of Drosophila pigment dispersing factor in neuronal subsets: The anatomical basis of a neuropeptide’s circadian functions, Orie T. Shafer and Paul H. Taghert

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Echogenic intracardiac foci: Associated with increased risk for fetal trisomy 21 or not?, Anthony L. Shanks, Anthony O. Odibo, and Diana L. Gray

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Application of three-level linear mixed-effects model incorporating gene-age interactions for association analysis of longitudinal family data, Gang Shi, Treva K. Rice, Chi Charles Gu, and Debeeru C. Rao

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Candidemia on presentation to the hospital: Development and validation of a risk score, Andrew F. Shorr, Ying P. Tabak, Richard S. Johannes, Xiaowu Sun, James Spalding, and Marin H. Kollef

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Cost-effectiveness analysis of a silver-coated endotracheal tube to reduce the incidence of ventilator-associated pneumonia, Andrew F. Shorr, Marya D. Zilberberg, and Marin Kollef

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Ion channels underlying stimulus-exocytosis coupling and its cell-to-cell heterogeneity in β-cells of transplantable porcine islets of Langerhans, Amelia M. Silva, Adam S. Dickey, David W. Barnett, and Stanley Misler

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A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet syndrome, Nanda A. Singh, Chris Pappas, E. Jill Dahle, Lieve R. F. Claes, Timothy H. Pruess, Peter De Jonghe, Joel Thompson, Missy Dixon, Christina Gurnett, Andy Peiffer, H. Steve White, Francis Filloux, and Mark F. Leppert

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Information technology resource management in radiation oncology, R. Alfredo Siochi, Peter Balter, Charles D. Bloch, Harry S. Bushe, Charles S. Mayo, Bruce H. Curran, Wenzheng Feng, George C. Kagadis, Thomas H. Kirby, and Robin L. Stern

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Systematic review of the role of sedation in diagnostic spinal interventional techniques, Howard S. Smith, Pradeep Chopra, Vikram B. Patel, Michael E. Frey, and Rahul Rastogi

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Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth, Neeleesh R. Soman, Steven L. Baldwin, Grace Hu, Jon N. Marsh, Gregory M. Lanza, John E. Heuser, Jeffrey M. Arbeit, Samuel A. Wickline, and Paul H. Schlesinger

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A novel role for Stat1 in phagosome acidification and natural host resistance to intracellular infection by Leishmania major, Gerald F. Spath, Paul Schlesinger, Robert Schreiber, and Stephen M. Beverley

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Bioinformatics methods for learning radiation-induced lung inflammation from heterogeneous retrospective and prospective data, Sarah J. Spencer, Damian Almiron Bonnin, Joseph O. Deasy, Jeffrey D. Bradley, and Issam El Naqa

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Improving the outcome of infants born at <30 >weeks' gestation - a randomized controlled trial of preventative care at home, Alicia J. Spittle, Carmel Ferretti, Peter J. Anderson, Jane Orton, Abbey Eeles, Lisa Bates, Roslyn N. Boyd, Terrie E. Inder, and Lex W. Doyle

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Reliability and validity of the Student Perceptions of School Cohesion Scale in a sample of Salvadoran secondary school students, Andrew E. Springer, Amy McQueen, Guillermo Quintanilla, Marcela Arrivillaga, and Michael W. Ross