The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2011

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Coordinated increase in inhibitory and excitatory synapses onto retinal ganglion cells during development, Florentina Soto, Adam Bleckert, Renate Lewis, Yunhee Kang, Daniel Kerschensteiner, Ann Marie Craig, and Rachel OL Wong

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A sensitive high-throughput assay for evaluating host-pathogen interactions in cryptococcus neoformans infection, Deepa Srikanta, Meng Yang, Matthew Williams, and Tamara L. Doering

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Catalytic and non-catalytic roles for the Mono-ADP-Ribosyltransferase Arr in the mycobacterial DNA damage response, Christina L. Stallings, Linda Chu, Lucy X. Li, and Michael S. Glickman

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CarD: A new RNA polymerase modulator in mycobacteria, Christina L. Stallings and Michael S. Glickman

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Crohn disease: A current perspective on genetics, autophagy and immunity, Thaddeus S. Stappenbeck, John D. Rioux, Atsushi Mizoguchi, Tatsuya Saitoh, Alan Huett, Arlette Darfeuille-Michaud, Tom Wileman, Noboru Mizushima, Simon Carding, Shizuo Akira, Miles Parkes, and Ramnik J. Xavier

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The [RNQ+] prion: A model of both functional and pathological amyloid, Kevin C. Stein and Heather L. true

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Oral acyclovir suppression and neurodevelopment after neonatal herpes, Gregory Storch and et al

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Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning, Melissa D. Stuchell-Brereton, Amanda Siglin, Jun Li, Jeffrey K. Moore, Shubbir Ahmed, John C. Williams, and John A. Cooper

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RNA binding protein CUGBP2/CELF2 mediates curcumin- induced mitotic catastrophe of pancreatic cancer cells, Dharmalingam Subramaniam, Satish Ramalingam, David C. Linehan, Brian K. Dieckgraefe, Russell G. Postier, Courtney W. Houchen, Roy A. Jensen, and Shrikant Anant

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Application of collapsing methods for continuous traits to the Genetic Analysis Workshop 17 exome sequence data, Yun Ju Sung, Treva K. Rice, and Dabeeru C. Rao

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Changes in events alter how people remember recent information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, and Jeffrey M. Zacks

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Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo, Melissa Swiecki, Yaming Wang, William Vermi, Susan Gilfillan, Robert D. Schreiber, and Marco Colonna

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Neural representation of temporal duration: coherent findings obtained with the “lossy integration” model, Olga V. Sysoeva, Marc Wittmann, and Jiri Wackermann

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Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3beta independent of JNK activation, Katsuya Tanabe, Yang Liu, Syed D. Hasan, Sara C. Martinez, Corentin Cras-Meneur, Cris M. Welling, Ernesto Bernal-Mizrachi, Yukio Tanizawa, Christopher J. Rhodes, Erik Zmuda, Tsonwin Hai, Nada A. Abumrad, and M. Alan Permutt

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Preschool onset attention-deficit/hyperactivity disorder: Course and predictors of stability over 24 months, Mini Tandon, Xuemei Si, and Joan Luby

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Targeting protein-protein interactions for parasite control, Christina M. Taylor, Kerstin Fischer, Sahar Abubucker, Zhengyuan Wang, John Martin, Daojun Jiang, Marc Magliano, Marie-Noelle Rosso, Ben-Wen Li, Peter U. Fischer, and Makedonka Mitreva

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Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis, Dick Terwel, Knut R. Steffensen, Philip B. Verghese, Markus P. Kummer, Jan-Åke Gustafsson, David M. Holtzman, and Michael T. Heneka

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Methylenetetrahydrofolate reductase genetic polymorphisms and toxicity to 5-FU-based chemoradiation in rectal cancer, Fabienne J. Thomas, Alison A. Motsinger-Reif, Janelle M. Hoskins, Anne M. Dvorak, Siddharth Roy, A. Alyasiri, Robert J. Myerson, James W. Fleshman, Benjamin Tan, and Howard L. McLeod

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Fibrocartilage tissue engineering: the role of the stress environment on cell morphology and matrix expression, Stavros Thomopoulos, Rosalina Das, Victor Birman, Lester Smith, Katherine Ku, Elliott L. Elson, Kenneth M. Pryse, Juan Pablo Marquez, and Guy M. Genin

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Consumption of single cigarettes and quitting behavior: A longitudinal analysis of Mexican smokers, James F. Thrasher, Victor Villalobos, Joaquin Barnoya, Raul Sansores, and Richard O'Connor

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Bioluminescence imaging captures the expression and dynamics of endogenous p21 promoter activity in living mice and intact cells, Kelsey L. Tinkum, Luciano Marpegan, Lynn S. White, Jinwu Sun, Erik D. Herzog, David Piwnica-Worms, and Helen Piwnica-Worms

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Ethanol enhances neurosteroidogenesis in hippocampal pyramidal neurons by paradoxical NMDA receptor activation, Kazuhiro Tokuda, Yukitoshi Izumi, and Charles F. Zorumski

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Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities, Hien T. Tran, Frank M. LaFerla, David M. Holtzman, and David L. Brody

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Lineage relationship of direct-developing melanocytes and melanocyte stem cells in the zebrafish, Robert C. Tryon, Charles W. Higdon, and Stephen L. Johnson

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The N-terminal, polybasic region is critical for prion protein neuroprotective activity, Jessie A. Turnbaugh, Laura Westergard, Ursula Unterberger, Emiliano Biasini, and David A. Harris

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Statistical analysis and interpretation of prenatal diagnostic imaging studies, part 2: Descriptive and inferential statistical methods, Methodius G. Tuuli and Anthony O. Odibo

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Implications of the prion-related Q/N domains in TDP-43 and FUS, Maria Udan and Robert H. Baloh

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Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medicalfood on pre-eclampsia in high risk population: Randomised controlled trial, Felipe Vadillo-Ortega, Otilia Perichant-Perera, Salvador Espino, Marco Antonio Avila-Vergara, Isabel Ibarra, Roberto Ahued, Myrna Godines, Samuel Parry, George Macones, and Jerome F. Strauss

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The transcriptional diversity of 25 Drosophila cell lines, Marijke J. van Baren, Laura Langton, Aaron E. Tenney, and Michael R. Brent

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bop5 mutations reveal new roles for the IC138 phosphoprotein in the regulation of flagellar motility and asymmetric waveforms, Kristyn E. VanderWaal, Ryosuke Yamamoto, Ken-ichi Wakabayashi, Laura Fox, Ritsu Kamiya, Susan K. Dutcher, Phillip V. Bayly, Winfield S. Sale, and Mary E. Porter

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Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus, Cassandra VanDunk, Lindsay A. Hunter, and Paul A. Gray

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Laparoscopic sleeve gastrectomy versus laparoscopic adjustable gastric banding for the treatment severe obesity in high risk patients, J. Esteban Varela

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Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuol, Iset Medina Vera, Wandy L. Beatty, Photini Sinnis, and Kami Kim

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Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo, Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, and John R. Cirrito

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Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense, R. Robert Vethanayagam, Nikolaos G. Almyroudis, Melissa J. Grimm, David C. Lewandowski, Christine T. N Pham, Timothy S. Blackwell, Ruta Petraitiene, Vidmantas Petraitis, Thomas J. Walsh, Constantin F. Urban, and Brahm H. Segal

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MicroRNAs modulate schwann cell response to nerve injury by reinforcing transcriptional silencing of dedifferentiation-related genes, Andreu Viader, Li-Wei Chang, Timothy Fahrner, Rakesh Nagarajan, and Jeffrey Milbrandt

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Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function, Andreu Viader, Judith P. Golden, Robert H. Baloh, Robert E. Schmidt, Daniel A. Hunter, and Jeffrey Milbrandt

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Differential regional and subtype-specific vulnerability of enteric neurons to mitochondrial dysfunction, Andreu Viader, Elizabeth C. Wright-Jin, Bhupinder P.S Vohra, Robert O. Heuckeroth, and Jeffrey Milbrandt

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Weight loss, exercise, or both and physical function in obese older adults, Dennis T. Villareal, Suresh Chode, Nehu Parimi, David R. Sinacore, Krupa Shah, Tiffany Hilton, Reina Armamento-Villareal, Nicola Napoli, and Clifford Qualls

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Phr1 is required for proper retinocollicular targeting of nasal-dorsal retinal ganglion cells, Bradley Q. Vo, A J. Bloom, and Susan M. Culican

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Exenatide improves glucose homeostasis and prolongs survival in a murine model of dilated cardiomyopathy, Arpita Kalla Vyas, Kai-Chen Yang, Dennis Woo, Anatoly Tzekov, Attila Kovacs, Patrick Y. Jay, and Paul W. Hruz

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Four-year longitudinal performance of a population-based sample of healthy children on a neuropsychological battery: The NIH MRI study of normal brain development, Deborah P. Waber, Peter W. Forbes, C. R. Almli, and Emily A. Blood

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Calling Cards enable multiplexed identification of the genomic targets of DNA-binding proteins, Haoyi Wang, David Mayhew, Xuhua Chen, Mark Johnston, and Robi David Mitra

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Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles, Jianbin Wang, Benjamin Czech, Amanda Crunk, Adam Wallace, Makedonka Mitreva, Gregory J. Hannon, and Richard E. Davis

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Measuring the impact of apnea and obesity on circadian activity patterns using functional linear modeling of actigraphy data, Jia Wang, Hong Xian, Amy Licis, Elena Deych, Jimin Ding, Jennifer McLeland, Cristina Toedebusch, Tao Li, Stephen Duntley, and William Shannon

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Gateways of ventral and dorsal streams in mouse visual cortex, Quanxin Wang, Enquan Gao, and Andreas Burkhalter

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Acute impact of moderate-intensity and vigorous-intensity exercise bouts on daily physical activity energy expenditure in postmenopausal women, Xuewen Wang and Barbara J. Nicklas

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Differential microbicidal effects of human histone proteins H2A and H2B on Leishmania promastigotes and amastigotes, Yingwei Wang, Yang Chen, Lijun Xin, Stephen M. Beverley, Eric D. Carlsen, Vsevolod Popov, Kwang-Poo Chang, Ming Wang, and Lynn Soong

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Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity, Yunyuan V. Wang, Mathias Leblanc, Norma Fox, Jian-Hua Mao, Kelsey L. Tinkum, Kurt Krummel, Dannielle Engle, David Piwnica-Worms, Helen Piwnica-Worms, Allan Balmain, Kenneth Kaushanszy, and Geoffrey M. Wahl

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Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression, Lukas D. Wartman, David E. Larson, Zhifu Xiang, Li Ding, Ken Chen, Ling Lin, Patrick Cahan, Jeffery M. Klco, John S. Welch, Cheng Li, Jacqueline E. Payton, Geoffrey L. Uy, Nobish Varghese, Rhonda E. Ries, and et al.

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Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling, Marcus Watkins, Susan K. Grimston, Jin Yi Norris, Bertrand Guillotin, Angela Shaw, Elia Beniash, and Roberto Civitelli

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Catheter-associated Nocardia higoensis bacteremia in a child with acute lymphocytic leukemia, Michael E. Watson Jr., Michele M. Eastabrook, and Carey-Ann D. Burnham

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Photo Quiz: A 2-year-old female with fever and rash, Michael E. Watson Jr., Gregory A. Storch, W. Michael Dunne Jr., and Carey-Ann D. Burnham

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Profile of ezogabine (retigabine) and its potential as an adjunctive treatment for patients with partial-onset seizures, Judith L.Z Weisenberg and Michael Wong

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Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans, Edward P. Weiss, Dennis T. Villareal, Luigi Fontana, Dong-Ho Han, and John O. Holloszy

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The duration of diarrhea and fever is associated with growth faltering in rural Malawian children aged 6-18 months, Ariana Weisz, Gus Meuli, Chrissie Thakwalakwa, Indi Trehan, Kenneth Maleta, and Mark Manary

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PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice, John S. Welch, Wenlin Yuan, and Timothy J. Ley

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The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance, Yi-Lan Weng, Nan Liu, Aaron DiAntonio, and Heather T. Broihier

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ISG15 is critical in the control of Chikungunya virus infection independent of UbE1L mediated conjugation, Scott W. Werneke, Clementine Schilte, Anjali Rohatgi, Kristen J. Monte, Alain Michault, Fernando Arenzana-Seisdedos, Dana L. Vanlandingham, Stephen Higgs, Arnaud Fontanet, Matthew L. Albert, and Deborah J. Lenschow

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A nine amino acid domain Is essential for mutant prion protein toxicity, Laura Westergard, Jessie A. Turnbaugh, and David A. Harris

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The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens, Luke A. Wiley, Ramya Rajagopal, Lisa K. Dattilo, and David C. Beebe

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Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study, Nathan E. Wineinger, Amit Patki, Kristin J. Meyers, Ulrich Broeckel, Charles C. Gu, DC Rao, Richard B. Devereux, Donna K. Arnett, and Herman K. Tiwari

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Risk estimates from an online risk calculator are more believable and recalled better when expressed as integers, Holly O. Witteman, Brian J. Zikmund-Fisher, Erika A. Waters, Teresa Gavaruzzi, and Angela Fagerlin

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Electronic surveillance for healthcare-associated central line-associated bloodstream infections outside the intensive care unit, Keith F. Woeltje, Kathleen M. McMullen, Anne M. Butler, Ashleigh J. Goris, and Joshua A. Doherty

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High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid- Lowering drugs and diet network (GOLDN): An interventional study, Mary K. Wojczynski, Stephen P. Glasser, Albert Oberman, Edmond K. Kabagambe, Paul N. Hopkins, Michael Y. Tsai, Robert J. Straka, Jose M. Ordovas, and Donna K. Arnett

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Physical activity and risk of colon adenoma: A meta-analysis, Kathleen Yaus Wolin, Yan Yan, and Graham A. Colditz

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New technologies in clinical microbiology, Donna M. Wolk and W. Michael Dunne Jr.

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Dietary carbohydrate modifies the inverse association between saturated fat intake and cholesterol on very low-density lipoproteins, A. C. Wood, E. K. Kabagambe, I. B. Borecki, H. K. Tiwari, J. M. Ordovas, and D. K. Arnett

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Lipoprotein Lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS, Alexis C. Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, and Donna K. Arnett

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A monthly quality assurance procedure for 3D surface imaging, H. Omar Wooten, Eric E. Klein, Garima Gokrhoo, and Lakshmi Santanam

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RhoA protects the mouse heart against ischemia/reperfusion injury, Sunny Yang Xiang, Davy Vanhoutte, Dominic P. Del Re, Nicole H. Purcell, Haiyun Ling, Indroneal Banerjee, Julie Bossuyt, Richard A. Lang, Yi Zheng, Scot J. Matkovich, Shigeki Miyamoto, Jeffrey D. Molkentin, Gerald W. Dorn II, and Joan Heller Brown

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A genomic storm in critically injured humans, Wenzhong Xiao, Bernard H. Brownstein, and et al

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Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site, Jinbin Xu, Chenbo Zeng, Wenhua Chu, Fenghui Pan, Justin M. Rothfuss, Fanjie Zhang, Zhude Tu, Dong Zhou, Dexing Zeng, Suwanna Vangveravong, Fabian Johnston, Dirk Spitzer, Katherine C. Chang, Richard S. Hotchkiss, William G. Hawkins, Robert H. Mach, and et al

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In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice, Kaoru Yamada, John R. Cirrito, Floy R. Stewart, Hong Jiang, Mary Beth Finn, Brandon B. Holmes, Lester I. Binder, Eva-Maria Mandelkow, Marc I. Diamond, Virginia M.-Y. Lee, and David M. Holtzman

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Accurate quantification of lipid species by electrospray ionization mass spectrometry - Meet a key challenge in lipidomics, Kui Yang and Xianlin Han

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Fig1 facilitates calcium influx and localizes to membranes destined to undergo fusion during mating in Candida albicans, Meng Yang, Alexandra Brand, Thyagarajan Srikantha, Karla J. Daniels, David R. Soll, and Neil A.R. Gow

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Enrichment analysis of genetic association in genes and pathways by aggregating signals from both rare and common variants, Wei Yang and C Charles Gu

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Binocular disparity tuning and visual–vestibular congruency of multisensory neurons in macaque parietal cortex, Yun Yang, Sheng Liu, Syed A. Chowdhury, Gregory C. DeAngelis, and Dora E. Angelaki

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A vertebrate case study of the quality of assemblies derived from next-generation sequences, Liang Ye, LaDeana W. Hillier, Patrick Minx, Nay Thane, Devin P. Locke, John C. Martin, Lei Chen, Makedonka Mitreva, Jason R. Miller, Kevin V. Haub, David J. Dooling, Elaine R. Mardis, Richard K. Wilson, George M. Weinstock, and Wesley C. Warren

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Elevated hemostasis markers after pneumonia increases one-year risk of all-cause and cardiovascular deaths, Sachin Yende, Gina D'Angelo, John A. Kellum, Lisa Weissfeld, A. Murat Kaynar, Tammy Young, Kaikobad Irani, and Derek C. Angus

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Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise, Tongjian You, Beth L. Disanzo, Xuewen Wang, Rongze Yang, and Dawei Gong

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Cholesterol tuning of BK ethanol response is enantioselective, and is a function of accompanying lipids, Chunbo Yuan, Maohui Chen, Douglas F. Covey, and Steven N. Treistman

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Prediction error associated with the perceptual segmentation of naturalistic events, Jeffrey M. Zacks, Christopher A. Kurby, Michelle L. Eisenberg, and Nayiri Haroutunian

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Multisensory calibration Is independent of cue reliability, Adam Zaidel, Amanda H. Turner, and Dora E. Angelaki

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mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists, Magda Zammataro, Santina Chiechio, Michael C. Montana, Anna Traficante, Agata Copani, Ferdinando Nicoletti, and Robert W. Gereau IV

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A mathematical model for the determination of steady-state cardiolipin remodeling mechanisms using lipidomic data, Lu Zhang, Robert J. A. Bell, Michael A. Kiebish, Thomas N. Seyfried, Xianlin Han, Richard W. Gross, and Jeffrey H. Chuang

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Methods for adjusting population structure and familial relatedness in association test for collective effect of multiple rare variants on quantitative traits, Qunyuan Zhang, Doyoung Chung, Aldi Kraja, Ingrid B. Borecki, and Michael A. Province

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Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair, Shichuan Zhang, Hirohiko Yajima, HoangDinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, and Benjamin P.C. Chen

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Improving Salmonella vector with rec mutation to stabilize the DNA cargoes, Xiangmin Zhang, Soo-Young Wanda, Karen Brenneman, Wei Kong, Xin Zhang, Kenneth Roland, and Roy Curtiss III

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Identification of DHX33 as a mediator of rRNA synthesis and cell growth, Yandong Zhang, Jason T. Forys, Alexander P. Miceli, Abigail S. Gwinn, and Jason D. Weber

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Transcriptome analysis of female and male Xiphophorus maculatus Jp 163 A, Ziping Zhang, Yilei Wang, Shuhong Wang, Jingtao Liu, Wesley Warren, Makedonka Mitreva, and Ronald B. Walter

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The genetic sonogram: Comparing the use of likelihood ratios versus logistic regression coefficients for Down syndrome screening, Yan Zhong, Ryan Longman, Rachael Bradshaw, and Anthony O. Odibo

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FlyFactorSurvey: A database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system, Lihua J. Zhu, Ryan G. Christensen, Majid Kazemian, Christopher J. Hull, Metewo S. Enuameh, Matthew D. Basciotta, Jessie A. Brasefield, Cong Zhu, Yuna Asriyan, David S. Lapointe, Saurabh Sinha, Scot A. Wolfe, and Michael H. Brodsky

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Pregnancy in multiple system atrophy: A case report, Lirong Zhu, Nigel J. Cairns, Samer D. Tabbal, and Brad A. Racette

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Do shared etiological factors contribute to the relationship between sexual orientation and depression?, B. P. Zietsch, K. J H Verweij, A. C. Heath, P. A F Madden, N. G. Martin, E. C. Nelson, and M. T. Lynskey

Submissions from 2010

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In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: Early gene expression profiling reveals possible drug target in AML, Anmaar M. Abdul-Nabi, Enas R. Yassin, Nobish Varghese, Hrishikesh Deshmukh, and Nabeel R. Yaseen

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Influenza vaccination among healthcare workers: Ten-year experience of a large healthcare organization, Cristina Ajenjo, Keith F. Woeltje, Hilary M. Babcock, Nancy Gemeinhart, Marilyn Jones, and Victoria J. Fraser

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Targeting of B and T lymphocyte associated (BTLA) prevents graft-versus-host disease without global immunosuppression, Jörn C. Albring, Michelle M. Sandau, Aaron S. Rapaport, Brian T. Edelson, Ansuman Satpathy, Mona Mashayekhi, Stephanie K. Lathrop, Chyi-Song Hsieh, Matthias Stelljes, Marco Colonna, Theresa L. Murphy, and Kenneth M. Murphy

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Blood meal analysis to identify reservoir hosts for Amblyomma americanum ticks, Brian F. Allan, Lisa S. Goessling, Gregory A. Storch, and Robert E. Thach

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VIPR: A probabilistic algorithm for analysis of microbial detection microarrays, Adam F. Allred, Guang Wu, Tuya Wulan, Kael F. Fischer, Michael R. Holbrook, Robert B. Tesh, and David Wang