The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2010

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Macaque parieto-insular vestibular cortex: Responses to self-motion and optic flow, Aihua Chen, Gregory C. DeAngelis, and Dora E. Angelaki

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A novel auxiliary subunit critical to BK channel function in caenorhabditis elegans, Bojun Chen, Qian Ge, Xiao-Ming Xia, Ping Liu, Sijie J. Wang, Haiying Zhan, Betty A. Eipper, and Zhao-Wen Wang

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Neoadjuvant endocrine therapy in primary breast cancer: Indications and use as a research tool, Yeehong Chia, M. J. Ellis, and Cynthia Ma

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Total raltegravir concentrations in cerebrospinal fluid exceed the 50-percent inhibitory concentration for wild-type HIV-1, David B. Clifford and et al

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Combined hip arthroscopy and limited open osteochondroplasty for anterior femoroacetabular impingement, John C. Clohisy, Lukas P. Zebala, Jeffrey J. Nepple, and Gail Pashos

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Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound, Jacquelynn J. Cook, Kristin R. Wildsmith, David B. Gilberto, Marie A. Holahan, Gene G. Kinney, Parker D. Mathers, Maria S. Michener, Eric A. Price, Mark S. Shearman, Adam J. Simon, Jennifer X. Wang, Guoxin Wu, Kevin E. Yarasheski, and Randall J. Bateman

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CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors, Joseph C. Corbo, Karen A. Lawrence, Marcus Karlstetter, Connie A. Myers, Musa Abdelaziz, William Dirkes, Karin Weigelt, Martin Seifert, Vladimir Benes, Lars G. Fritsche, Bernhard H.F. Weber, and Thomas Langmann

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Evaluation of a chromogenic agar for detection of group B streptococcus in pregnant women, Robin R. Craven, Carol J. Weber, Rebecca A. Jennemann, and W. Michael Dunne Jr.

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Growth modulation by means of anterior tethering resulting in progressive correction of juvenile idiopathic scoliosis: A case report, Charles H. Crawford and Lawrence G. Lenke

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Phospholipase C gamma 2 Is critical for development of a murine model of inflammatory arthritis by affecting actin dynamics in dendritic cells, Viviana Cremasco, Elisa Benasciutti, Marina Cella, Marina Kisseleva, Monica Croke, and Roberta Faccio

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A PPARalpha promoter variant impairs ERR-dependent transactivation and decreases mortality after acute coronary ischemia in patients with diabetes, Sharon Cresci, Janice M. Huss, Amber L. Beitelshees, Philip G. Jones, Matt R. Minton, Gerald W. Dorn II, Daniel P. Kelly, John A. Spertus, and Howard L. McLeod

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Promoter and Riboswitch Control of the Mg2+ Transporter MgtA from Salmonella enterica, Michael J. Cromie and Eduardo A. Groisman

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SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer’s disease, Carlos Cruchaga, John S. K. Kauwe, Kevin Mayo, Noah Spiegel, Sarah Bertelsen, Petra Nowotny, Aarti R. Shah, Richard Abraham, Paul Holligworth, Denise Harold, Michael M. Owen, Julie Williams, Simon Lovestone, Elaine R. Peskind, Ge Li, James B. Leverenz, Douglas Galasko, The Alzheimer's Disease Neuroimaging Initiative, John C. Morris, Anne M. Fagan, David M. Holtzman, and Alison M. Goate

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Virulence plasmid harbored by uropathogenic Escherichia coli functions in acute stages of pathogenesis, Corinne K. Cusumano, Chia S. Hung, Swaine L. Chen, and Scott J. Hultgren

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Lipids driving protein structure? Evolutionary adaptations in Kir channels, Nazzareno D'Avanzo, Wayland W.L. Chang, Shizhen Wang, Decha Enkvetchakul, and Colin G. Nichols

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Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery, Paula Dennen, Christopher Altmann, Jonathan Kaufman, Christina L. Klein, Ana Andres-Hernando, Nilesh H. Ahuja, Charles L. Edelstein, Melissa A. Cadnapaphornchai, Angela Keniston, and Sarah Faubel

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Splenic injury during percutaneous nephrolithotomy: A case report with novel management technique, Alana C. Desai, Samay Jain, Brian M. Benway, Robert L. Grubb III, Daniel Picus, and Robert S. Figenshau

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Tuboovarian abscesses: Is size associated with duration of hospitalization & complications?, Jason DeWitt, Angela Reining, Jenifer E. Allsworth, and Jeffrey F. Peipert

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Charting the progression of disability in Parkinson disease: Study protocol for a prospective longitudinal cohort study, Leland E. Dibble, James T. Cavanaugh, Gammon M. Earhart, Terry D. Ellis, Matthew P. Ford, and Kenneth B. Foreman

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Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells, Hans H. Dietrich, Chuanxi Xiang, Byung H. Han, Gregory J. Zipfel, and David M. Holtzman

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Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern, Deborah E. Dobson, Shaden Kamhawi, Phillip Lawyer, Salvatore J. Turco, Stephen M. Beverley, and David L. Sacks

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It's not easy being green: The viridans group streptococci, with a focus on pediatric clinical manifestations, Christpher D. Doern and Carey-Ann D. Burnham

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Self versus environment motion in postural control, Kalpana Dokka, Robert V. Kenyon, Emily A. Keshner, and Konrad P. Kording

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Remember the source: Dissociating frontal and parietal contributions to episodic memory, David I. Donaldson, Mark E. Wheeler, and Steve E. Petersen

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Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure, Gerald W. Dorn II

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Cerenkov radiation energy transfer (CRET) imaging: A novel method for optical imaging of PET isotopes in biological systems, Robin S. Dothager, Reece J. Goiffon, Erin Jackson, Scott Harpstrite, and David Piwnica-Worms

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Magnesium induces neuronal apoptosis by suppressing excitability, W. H. Dribben, L. N. Eisenman, and S. Mennerick

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Prevention of healthcare-associated Clostridium difficile infection: What works?, Erik R. Dubberke

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Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin, Alexis Dumortier, Andre-Dante Durham, Matteo Di Piazza, Sophie Vauclair, Ute Koch, Gisele Ferrand, Isabel Ferrero, Shadmehr Demehri, Lynda Li Song, Andrew G. Farr, Warren J. Leonard, Raphael Kopan, Lucio Miele, Daniel Hohl, Daniel Finke, and Freddy Radtke

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Inflammatory monocytes but not neutrophils are necessary to control infection with Toxoplasma gondii in mice, Ildiko R. Dunay, Anja Fuchs, and L. David Sibley

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Enhancement of anti-DIII antibodies by the C3d derivative P28 results in lower viral titers and augments protection in mice, Matthew D. Dunn, Shannon L. Rossi, Donald M. Carter, Matthew R. Vogt, Erin Mehlhop, Michael S. Diamond, and Ted M. Ross

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CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow, Kyle J. Eash, Adam M. Greenbaum, Priya K. Gopalan, and Daniel C. Link

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Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells, Brian T. Edelson, Wumesh KC, Richard Juang, Masako Kohyama, Loralyn A. Benoit, Paul A. Klekotka, Clara Moon, Jörn C. Albring, Wataru Ise, Drew G. Michael, Deepta Bhattacharya, Thaddeus S. Stappenbeck, Michael J. Holtzman, Sun-Sang J. Sung, Theresa L. Murphy, Kai Hildner, and Kenneth M. Murphy

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Improving prefrontal cortex function in schizophrenia through focused training of cognitive control, Bethany G. Edwards, Deanna M. Barch, and Todd S. Braver

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Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns, John R. Edwards, Anne H. O'Donnell, Robert A. Rollins, Heather E. Peckham, Clarence Lee, Maria H. Milekic, Benjamin Chanrion, Yutao Fu, Tao Su, Hanina Hibshoosh, Jay A. Gingrich, Fatemeh Haghighi, Robert Nutter, and Timothy H. Bestor

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p38δ mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis, Tatiana Efimova

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Multiple pathways of inhibition shape bipolar cell responses in the retina, Erika D. Eggers and Peter D. Lukasiewicz

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MHC class I–deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I–sufficient environment, Julie M. Elliott, Joseph A. Wahle, and Wayne M. Yokoyama

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Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism, Laura A. Engel, Zheng Jing, Daniel E. O’Brien, Mengyang Sun, and Paul T. Kotzbauer

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Gene-expression profiling for rejection surveillance after cardiac transplantation, Gregory A. Ewald and et al

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Next-generation sequencing identifies the natural killer cell microRNA transcriptome, Todd A. Fehniger, Todd Wylie, Elizabeth Germino, Jeffrey W. Leong, Vincent J. Magrini, Sunita Koul, Catherine R. Keppel, Stephanie E. Schneider, Daniel C. Koboldt, Ryan P. Sullivan, Michael E. Heinz, Seth D. Crosby, Rakesh Nagarajan, Giridharan Ramsingh, Daniel C. Link, Timothy J. Ley, and Elaine R. Mardis

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Multiplexed echo planar imaging for sub-second whole brain fMRI and fast diffusion imaging, David A. Feinberg, Steen Moeller, Stephen M. Smith, Edward Auerbach, Sudhir Ramanna, Matt F. Glasser, Karla L. Miller, Kamil Ugurbil, and Essa Yacoub

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Major depression and the metabolic syndrome, Debra L. Foley, Katherine I. Morley, Pamela A.F. Madden, Andrew C. Heath, John B. Whitfield, and Nicholas G. Martin

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Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells, Sonya G. Fonseca, Shinsuke Ishigaki, Christine M. Oslowski, Simin Lu, Kathryn L. Lipson, Rajarshi Ghosh, Emiko Hayashi, Hisamitsu Ishihara, Yoshitomo Oka, M. Alan Permutt, and Fumihiko Urano

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Structural homology between the C-terminal domain of the PapC usher and its plug, Bradley Ford, Ana Toste Rêgo, Timothy J. Ragan, Jerome Pinkner, Karen Dodson, Paul C. Driscoll, Scott Hultgren, and Gabriel Waksman

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Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial, Benjamin French, Jungnam Joo, Nancy L. Geller, Stephen E. Kimmel, Yves Rosenberg, Jeffrey L. Anderson, Brian F. Gage, Julie A. Johnson, Jonas H. Ellenberg, and COAG Investigators

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Age-related synaptic loss of the medial olivocochlear efferent innervation, Benjamin Fu, Colleen Le Prell, Dwayne Simmons, Debin Lei, Angela Schrader, Amelia B. Chen, and Jianxin Bao

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Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking, Rodrigo A. Fuentealba, Qiang Liu, Juan Zhang, Takahisa Kanekiyo, Xiaoyan Hu, Jin-Moo Lee, Mary Jo LaDu, and Guojun Bu

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VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans, Keiko Fujikawa, Takeshi Iwata, Kaoru Inoue, Masakazu Akahori, Hanako Kadotani, Masahiro Fukaya, Masahiko Watanabe, Qing Chang, Edward M. Barnett, and Wojciech Swat

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Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes, Kei Fujimoto, Eric L. Ford, Hung Tran, Burton M. Wice, Seth D. Crosby, Gerald W. Dorn II, and Kenneth S. Polonsky

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The impact of packed red blood cell transfusion on clinical outcomes in patients with septic shock treated with early goal directed therapy, Brian M. Fuller, Mithil Gajera, Christa Schorr, David Gerber, R. Phillip Dellinge, Joseph Parrillo, and Sergio Zanotti

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Parallel input channels to mouse primary visual cortex, Enquan Gao, Gregory C. DeAngelis, and Andreas Burkhalter

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Identification of hookworm DAF-16/FOXO response elements and direct gene targets, Xin Gao, Zhengyuan Wang, John Martin, Sahar Abubucker, Xu Zhang, Makedonka Mitreva, and John M. Hawdon

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To-and-fro murmur in the young due to major congenital cardiac defects: Is cardiac auscultation obsolete?, Avihu Z. Gazit, Gautam K. Singh, and Mark C. Johnson

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Dyskerin ablation in mouse liver inhibits rRNA processing and cell division, Jingping Ge, David A. Rudnick, Jun He, Dan L. Crimmins, Jack H. Ladenson, Monica Bessler, and Philip J. Mason

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Orthopaedic surgeons and the medical device industry: The threat to scientific integrity and the public trust, Richard H. Gelberman, David Samson, Sohail K. Mirza, John J. Callaghan, and Vincent D. Pellegrini

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Gene–environment interactions at nucleotide resolution, Justin Gerke, Kim Lorenz, Shelina Ramnarine, and Barak Cohen

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Multicenter study of clinical performance of the 3M rapid detection RSV test, Christine C. Ginocchio, Ella Swierkosz, Alexander J. McAdam, Mario Marcon, Gregory A. Storch, Alexandra Valsamakis, Stefan Juretschko, José Romero, and Belinda Yen-Lieberman

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Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo, Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J. Holtzman, and Marco Colonna

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Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease, Alison M. Goate, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin Mayo, and et al.

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RET signaling is required for survival and normal function of nonpeptidergic nociceptors, Judith P. Golden, Masato Hoshi, Mohammed A. Nassar, Hideki Enomoto, John N. Wood, Jeffrey Milbrandt, Robert W. Gereau IV, Eugene M. Johnson Jr, and Sanjay Jain

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Human mucosal associated invariant T cells detect bacterially infected cells, Marielle C. Gold, Stefanie Cerri, Susan Smyk-Pearson, Meghan E. Cansler, Todd M. Vogt, Jacob Delepine, Ervina Winata, Gwendolyn M. Swarbrick, Wei-Jen Chua, Yik Y. L. Yu, Olivier Lantz, Matthew S. Cook, Megan D. Null, David B. Jacoby, Melanie J. Harriff, Deborah A. Lewinsohn, Ted H. Hansen, and David M. Lewinsohn

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Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation, Veronica Gomez-Godinez, Tao Wu, Adria J. Sherman, Christopher S. Lee, Lih-Huei Liaw, You Zhongsheng, Kyoko Yokomori, and Michael W. Berns

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Multiple interaction domains in FtsL, a protein component of the widely conserved bacterial FtsLBQ cell division complex, Mark D. Gonzalez, Esra A. Akbay, Dana Boyd, and Jon Beckwith

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Nurturing the genome: A-type lamins preserve genomic stability, Ignacio Gonzalez-Suarez and Susana Gonzalo

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Sit and Stay a While: How BfiSR Controls Irreversible Attachment in Pseudomonas aeruginosa Biofilms, Andrew L. Goodman

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The Haemophilus influenzae HMW1C protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin, Susan Grass, Cheryl F. Lichti, R. Reid Townsend, Julia Gross, and Joseph W. St. Geme III

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Developmental origin of preBötzinger complex respiratory neurons, Paul A. Gray, John A. Hayes, Guang Y. Ling, Isabel Llona, Srinivasan Tupal, Maria C.D. Picardo, Sarah E. Ross, Tsutomu Hirata, Joshua G. Corbin, Jaime Eugenín, and Christopher A. Del Negro

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Brain specificity of diffuse optical imaging: improvements from superficial signal regression and tomography, Nicholas M. Gregg, Brian R. White, Benjamin W. Zeff, Andrew J. Berger, and Joseph P. Culver

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Serological evidence of human klassevirus infection, Alexander L. Greninger, Lori Holtz, Gagandeep Kang, Donald Ganem, David Wang, and Joseph L. DeRisi

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Molecular remodeling of ion channels, exchangers and pumps in atrial and ventricular myocytes in ischemic cardiomyopathy, Naomi Gronich, Azad Kumar, Yuwei Zhang, Igor R. Efimov, and Nikolai M. Soldatov

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Vesicular neurotransmitter transporter trafficking in vivo: Moving from cells to flies, Anna Grygoruk, Hao Fei, Richard W. Daniels, Bradley R. Miller, Audrey Chen, Aaron DiAntonio, and David E. Krantz

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Enterococcal biofilm formation and virulence in an optimized murine model of foreign body-associated urinary tract infections, Pascale S. Guiton, Chia S. Hung, Lynn E. Hancock, Michael G. Caparon, and Scott J. Hultgren

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Histone modifications during mammalian oocyte maturation: Dynamics, regulation and functions, Ling Gu, Qiang Wang, and Qing-Yuan Sun

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Construction of recombinant attenuated Salmonella enterica serovar typhimurium vaccine vector strains for safety in newborn and infant mice, Bronwyn M. Gunn, Soo-Young Wanda, Dana Burshell, Caihong Wang, and Roy Curtiss III

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The effects of a secondary task on forward and backward walking in Parkinson’s disease, Madeleine E. Hackney and Gammon M. Earhart

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A monoclonal antibody toolkit for C. elegans, Gayla Hadwiger, Scott Dour, Swathi Arur, Paul Fox, and Michael L. Nonet

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Organogenetic tolerance, Marc R. Hammerman

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Evaluation and management of inherited disorders of surfactant metabolism, Aaron Hamvas

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Early severe inflammatory responses to uropathogenic E. coli predispose to chronic and recurrent urinary tract infection, Thomas J. Hannan, Indira U. Mysorekar, Chia S. Hung, Megan L. Isaacson-Schmid, and Scott J. Hultgren

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Current strategies for the prevention and management of central line-associated bloodstream infections, Zhuolin Han, Stephen Y. Liang, and Jonas Marschall

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Defining the plasticity of transcription factor binding sites by deconstructing DNA consensus sequences: The PhoP-binding sites among gamma/enterobacteria, Oscar Harari, Sun-Yang Park, Henry Huang, Eduardo A. Groisman, and Igor Zwir

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Thymoglobulin induction dosing strategies in a low-risk kidney transplant population: Three or four days?, Karen L. Hardinger, Rafia S. Rasu, Rebecca Skelton, Brent W. Miller, and Daniel C. Brennan

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Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step, Brooke Harmon, Nancy Campbell, and Lee Ratner

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Do race-specific definitions of short long bones improve the detection of Down syndrome on second-trimester genetic sonograms?, Lorie M. Harper

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Development and preliminary reliability testing of an assessment of patient independence in performing a treatment program: Standardized scenarios, Marcie Harris-Hayes, Gregory W. Holtzman, Jeanne A. Earley, and Linda R. Van Dillen

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Wormbase: A comprehensive resource for nematode research, Todd W. Harris, Igor Antoshechkin, Tamberlyn Bieri, Darin Blasiar, Juancarlos Chan, Wen J. Chen, Norie De La Cruz, Paul Davis, Margaret Duesbury, Ruihua Fang, Jolene Fernandes, Michael Han, Ranjana Kishore, Raymond Lee, Hans-Michael Muller, Cecilia Nakamura, Philip Ozersky, Andrei Petcherski, Arun Rangarajan, Anthony Rogers, Gary Schindelman, Erich M. Schwarz, Mary Ann Tuli, Kimberly Van Auken, Daniel Wang, Xiaodong Wang, Gary Williams, Karen Yook, Richard Durbin, Lincoln D. Stein, John Spieth, and Paul W. Sternberg

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Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice, Björn Hartleben, Markus Gödel, Catherine Meyer-Schwesinger, Shuya Liu, Theresa Ulrich, Sven Köbler, Thorsten Wiech, Florian Grahammer, Andrey S. Shaw, Noburu Mizushima, Dontscho Kerjaschki, Hermann Pavenstadt, Clemens D. Cohen, Maja T. Lindenmeyer, Sebastian J. Arnold, and et al

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Robot-assisted partial nephrectomy: Evaluation of learning curve for an experienced renal surgeon, Mohammed Haseebuddin, Brian M. Benway, Jose M. Cabello, and Sam B. Bhayani

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Golgi cells operate as state-specific temporal filters at the input stage of the cerebellar cortex, Shane A. Heine, Stephen M. Highstein, and Pablo M. Blazquez

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A surface-based analysis of hemispheric asymmetries and folding of cerebral cortex in term-born human infants, Jason Hill, Donna Dierker, Jeffrey Neil, Terrie Inder, Andrew Knutsen, John Harwell, Timothy Coalson, and David Van Essen

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Reducing the incidence of intraventricular catheter-related ventriculitis in the neurology-neurosurgical intensive care unit at a tertiary care center in St Louis, Missouri: An 8-year follow-up study, Hitoshi Honda, Jeffrey C. Jones, Martha C. Craighead, Michael N. Diringer, Ralph G. Dacey, and David K. Warren

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The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine, John R. Hornick, Jinbin Xu, Suwanna Vangveravong, Zhude Tu, Jonathan B. Mitchem, Dirk Spitzer, Peter Goedegebuure, Robert H. Mach, and William G. Hawkins

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Immunotherapy for sepsis - A new approach against an ancient foe, Richard S. Hotchkiss and Steven Opal

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Sliding set-points of immune responses for therapy of autoimmunity, Chyi-Song Hsieh and Jhoanne Lynne Bautista

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Aldo-keto reductases in the eye, Shun Ping Huang, Suryanarayana Palla, Philip Ruzycki, Ross Arjun Varma, Theresa Harter, G. Bhanuprakesh Reddy, and J. Mark Petrash

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Lipidomics analysis reveals efficient storage of hepatic triacylglycerides enriched in unsaturated fatty acids after one bout of exercise in mice, Chunxiu Hu, Miriam Hoene, Xinjie Zhao, Hans U. Haring, Erwin Schleicher, Rainer Lehmann, Xianlin Han, Guowang Xu, and Cora Weigert

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Reproducibility of placental volume and vasculature indices obtained by 3-dimensional power Doppler sonography, Kristina M. Huster, Kimberly Haas, Jean Schoenborn, Dominique McVean, and Anthony O. Odibo

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Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization, Yuji Ito, Steven L. Teitelbaum, Wei Zou, Yi Zheng, James F. Johnson, Jean Chappel, F. Patrick Ross, and Haibo Zhao

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Deep sequencing of small RNA libraries reveals dynamic regulation of conserved and novel microRNAs and microRNA-stars during silkworm development, Guru Jagadeeswaran, Yun Zheng, Niranji Sumathipala, Haobo Jiang, Estela L. Arrese, Jose L. Soulages, Weixiong Zhang, and Ramanjulu Sunkar