The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2011
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits, Rita PS Middelberg, Manuel AR Ferreira, Anjali K. Henders, Andrew C. Heath, Pamela AF Madden, Grant W. Montgomery, Nicholas G. Martin, and John B. Whitfield
Organogenesis of the kidney glomerulus: Focus on the glomerular basement membrane, Jeffrey H. Miner
Cost effectiveness of interventions to promote screening for colorectal cancer: A randomized trial, Swati Misra, David R. Lairson, Wenyaw Chan, Yu-Chia Chang, L. Kay Bartholomew, Anthony Greisinger, Amy McQueen, and Sally W. Vernon
Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion, James F. Mohan, Shirley J. Petzold, and Emil R. Unanue
Functional metagenomic investigations of the human intestinal microbiota, Aimee M. Moore, Christian Munck, Morten O.A Sommer, and Gautam Dantas
Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome, Thomas M. Morgan, John A. House, Sharon Cresci, Philip Jones, Hooman Allayee, Stanley L. Hazen, Yesha Patel, Riyaz S. Patel, Danny J. Eapen, Salina P. Waddy, Arshed A. Quyyumi, Marcus E. Kleber, Winfried Marz, Bernhard R. Winkelmann, Bernhard O. Boehm, Harlan M. Krumholz, and John A. Spertus
Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis, Maiko Moriyama, Takeshi Fukuhara, Markus Britschgi, Yingbo He, Ramya Narasimhan, Saul Villeda, Hector Mollina, Brigitte T. Huber, Mike Holers, and Tony Wyss-Coray
Assessing the effects of symmetry on motif disovery and modeling, Lala M. Motlhabi and Gary D. Stormo
Biome representational in silico karyotyping, Valliammai Muthappan, Aaron Y. Lee, Tamara L. Lamprecht, Lakshmi Akileswaran, Suzanne M. Dintzis, Choli Lee, Vincent Magrini, Elaine R. Mardis, Jay Shendure, and Russell N. Van Gelder
Diversity of the autochthonous colonic microbiota, Gerardo M. Nava and Thaddeus S. Stappenbeck
Specific sequence determinants of miR-15/107 microRNA gene group targets, Peter T. Nelson, Wang-Xia Wang, Guogen Mao, Bernard R. Wilfred, Kevin Xie, Mary H. Jennings, Zhen Gao, and Xiaowei Wang
Ajuba is required for Rac activation and maintenance of E-cadherin adhesion, Sébastien Nola, Reiko Daigaku, Kasia Smolarczyk, Maryke Carstens, Belen Martin-Martin, Gregory Longmore, Maryse Bailly, and Vania M.M. Braga
Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene: evidence for assortative mating, Peg Nopoulos, Eric A. Epping, Tom Wassink, Bradley L. Schlaggar, and Joel Perlmutter
Original research: Trauma exposure and posttraumatic stress disorder among employees of New York City companies affected by the september 11, 2001 attacks on the World Trade Center, Carol S. North, David E. Pollio, Rebecca P. Smith, Richard V. King, Anand Pandya, Alina M. Suris, Barry A. Hong, Denis J. Dean, Nancy E. Wallace, Daniel B. Herman, Sarah Conover, Ezra Susser, and Betty Pfefferbaum
Biomedical and psychosocial factors associated with disability after peripheral nerve injury, Christine B. Novak, Dimitri J. Anastakis, Dorcas E. Beaton, Susan E. Mackinnon, and Joel Katz
Clinical presentation of symptomatic acetabular dysplasia in skeletally mature patients, Ryan M. Nunley, Heidi Prather, Devyani Hunt, Perry L. Schoenecker, and John C. Clohisy
Risk factors associated with Hepatitis C among female substance users enrolled in communitybased HIV prevention studies, Diana Nurutdinova, Arbi B. Abdallah, Susan Bradford, Catina C. O'Leary, and Linda B. Cottler
Five questions about non-mevalonate isoprenoid biosynthesis, Audrey R. Odom
Resistance of canine lymphoma cells to adenoviral infection due to reduced cell surface RGD binding integrins, Ann Marie O'Neill, Annette N. Smith, Elizabeth A. Spangler, Elizabeth M. Whitley, Stephanie E. Schleis, Richard C. Bird, David T. Curiel, Erin E. Thacker, and Bruce F. Smith
A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila, Laura Palanker Musselman, Jill L. Fink, Kirk Narzinski, Prasanna Venkatesh Ramachandran, Sumitha Sukumar Hathiramani, Ross L. Cagan, and Thomas J. Baranski
Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle, Ryan Parker, Jin-Shan Wang, Vladimir J. Kefalov, and Rosalie K. Crouch
Bioluminescent imaging reveals divergent viral pathogenesis in two strains of stat1-deficient mice, and in αßγ interferon receptor-deficient mice, Tracy Jo Pasieka, Lynne Collins, Megan A. O'Connor, Yufei Chen, Zachary M. Parker, Brent L. Berwin, David R. Piwnica-Worms, and David A. Leib
Structure and dynamics of glycosphingolipids in lipid bilayers: Insights from molecular dynamics simulations, Ronak Y. Patel and Petety V. Balaji
Comparison of through-focus image quality across five presbyopia-correcting intraocular lenses (an American Ophthalmological Society Thesis), Jay S. Pepose, Daozhi Wang, and Griffith E. Altmann
A temporal role Of Type I interferon signaling in CD8+ T Cell maturation during acute West Nile virus infection, Amelia K. Pinto, Stephane Daffis, James D. Brien, Maria D. Gainey, Wayne M. Yokoyama, Kathleen C.F Sheehan, Kenneth M. Murphy, Robert D. Schreiber, and Michael S. Diamond
An evolutionary genomic approach to identify genes involved in human birth timing, Jevon Plunkett, Scott Doniger, Guilherme Orabona, Thomas Morgan, Ritva Haataja, Mikko Hallman, Hilkka Puttonen, Ramkumar Menon, Edward Kuczynski, Errol Norwitz, Victoria Snegovskikh, Aarno Palotie, Leena Peltonen, Vineta Fellman, Emily A. DeFranco, Bimal P. Chaudhari, Tracy L. McGregor, Jude J. McElroy, Matthew T. Oetjens, Kari Teramo, Ingrid Borecki, Justin Fay, and Louis Muglia
SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer, Megana K. Prasad, Xylena Reed, David U. Gorkin, Julia C. Cronin, Anthony R. McAdow, Kristopher Chain, Chani J. Hodonsky, Erin A. Jones, John Svaren, Anthony Antonellis, Stephen L. Johnson, Stacie K. Loftus, William J. Pavan, and Andrew S. McCallion
Single-lung transplantation in the setting of aborted bilateral lung transplantation, Varun Puri, Tracey Guthrie, Masina Scavuzzo, Daniel Kreisel, Alexander S. Krupnick, G. Alexander Patterson, and Bryan F. Meyers
Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants, Whitney E. Purtha, Thomas F. Tedder, Syd Johnson, Deepta Bhattacharya, and Michael S. Diamond
Study of rotational dynamics of receptor-targeted contrast agents in cancerous and normal prostate tissues using time-resolved picosecond emission spectroscopy, Yang Pu, Wubao B. Wang, Samuel Achilefu, and Robert R. Alfano
Incidence of symptomatic venous thromboembolism in oncologic patients undergoing lower-extremity endoprosthetic arthroplasty, Brandon A. Ramo, Anthony M. Griffin, Corey S. Gill, Douglas J. McDonald, Jay S. Wunder, Peter Ferguson, Robert S. Bell, Sharon E. Phillips, Herbert S. Schwartz, and Ginger E. Holt
Toward an interactive article: Integrating journals and biological databases, Arun Rangarajan, Tim Schedl, Karen Yook, Juancarlos Chan, Stephen Haenel, Lolly Otis, Sharon Faelten, Tracey DePellegrin-Connelly, Ruth Isaacson, Marek S. Skrzypek, Steven J. Marygold, Raymund Raymund, J Michael Cherry, Paul W. Sternberg, and Hans-Michael Müller
Targeting HTLV-1 Activation of NFκB in Mouse Models and ATLL Patients, Daniel A. Rauch and Lee Ratner
IL-15 deficiency promotes tumor growth in tax transgenic mice, Daniel Rauch, Sirosh Bokhari, John Harding, and Lee Ratner
Tet-inducible lymphoma in a new Tax transgenic mouse model, Daniel Rauch, Sirosh Bokhari, John Harding, and Lee Ratner
The effects of XMRV gene expression on the mouse prostate, Daniel Rauch, Sirosh Bokhari, John Harding, and Lee Ratner
Regulating the levels of key factors in cell cycle and DNA repair: New pathways revealed by lamins, Abena B. Redwood, Ignacio Gonzalez-Suarez, and Susana Gonzalo
A dual role for A-type lamins in DNA double-strand break repair, Abena B. Redwood, Stephanie M. Perkins, Robert P. Vanderwaal, Zhihui Feng, Kenneth J. Biehl, Ignacio Gonzalez-Suarez, Lucia Morgado-Palacin, Wei Shi, Julien Sage, Joseph L. Roti-Roti, Colin L. Stewart, Junran Zhang, and Susana Gonzalo
A behavioral analysis of spatial neglect and its recovery after stroke, Jennifer Rengachary, Biyu J. He, Gordon L. Shulman, and Maurizio Corbetta
What's new in orthopaedic trauma, William M. Ricci, Christopher McAndrew, David Merriman, and Michael J. Gardner
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin, Nicole C. Riddle, Sarah C.R. Elgin, and et al
RNA interference in marine and freshwater sponges: actin knockdown in Tethya wilhelma and Ephydatia muelleri by ingested dsRNA expressing bacteria, Ajna S. Rivera, Jorg U. Hammel, Karri M. Haen, Elizabeth S. Danka, Brandon Cieniewicz, Ian P. Winters, Dora Posfai, Gert Worheide, Dennis V. Lavrov, Scott W. Knight, Malcolm S. Hill, April L. Hill, and Michael Nickel
Engraftment of cells from porcine islets of Langerhans following transplantation of pig pancreatic primordia in non-immunosuppressed diabetic rhesus macaques, Sharon A. Rogers, Piyush Tripathi, Thalachallour Mohanakumar, Helen Liapis, Feng Chen, Michael R. Talcott, Chad Faulkner, and Marc R. Hammerman
Muco-cutaneous leishmaniasis in the New World: The ultimate subversion, Catherine Ronet, Stephen M. Beverley, and Nicolas Fasel
Leukemia cutis in B-cell chronic lymphocytic leukemia presenting as an episodic papulovesicular eruption, Ilana S. Rosman, Kara S. Nunley, and Dongsi Lu
Caenorhabditis briggsae recombinant inbred line genotypes reveal inter-strain incompatibility and the rvolution of recombination, Joseph A. Ross, Daniel C. Koboldt, Julia E. Staisch, Helen M. Chamberlin, Bhagwati P. Gupta, Raymond D. Miller, Scott E. Baird, and Eric S. Haag
Short-term plasticity optimizes synaptic information transmission, Ziv Rotman, Pan-Yue Deng, and Vitaly A. Klyachko
New tools and methods for direct programmatic access to the dbSNP relational database, Scott F. Saccone, Jiaxi Quan, Gaurang Mehta, Raphael Bolze, Prasanth Thomas, Ewa Deelman, Jay A. Tischfield, and John P. Rice
Nonlinear interactions between excitatory and inhibitory retinal synapses control visual output, Botir T. Sagdullaev, Erika D. Eggers, Robert Purgert, and Peter D. Lukasiewicz
Role of guanylyl cyclase modulation in mouse cone phototransduction, Keisuke Sakurai, Jeannie Chen, and Vladimir J. Kefalov
Cerebral infarction following a seizure in a patient with subarachnoid hemorrhage complicated by delayed cerebral ischemia, Tomoko Rie Sampson, Rajat Dhar, and Gregory J. Zipfel
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer, Cesar G. Sanchez, Cynthia X. Ma, Robert J. Crowder, Therese Guintoli, Chanpheng Phommaly, Feng Gao, Li Lin, and Matthew J. Ellis
Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion, Narenda V. Sankpal, John D. Mayfield, Mike W. Willman, Timothy P. Fleming, and William E. Gillanders
Managing stress in the orthopaedic family: Avoiding burnout, achieving resilience, M. Catherine Sargent, Wayne Sotile, Mary O. Sotile, Harry Rubash, Peter S. Vezeridis, Larry Harmon, and Robert L. Barrack
Year in review 2010: Critical Care- neurocritical care, Michael T. Scalfani and Michael N. Diringer
The awesome power of yeast evolutionary genetics: New genome sequences and strain resources for the Saccharomyces sensu stricto genus, Devin R. Scannell, Oliver A. Zill, Antonis Rokas, Celia Payen, Maitreya J. Dunham, Michael B. Eisen, Jasper Rine, Mark Johnston, and Chris Todd Hittinger
A test for common genetic and environmental vulnerability to depression and diabetes, Jeffrey F. Scherrer, Hong Xian, Patrick J. Lustman, Carol E. Franz, Jeanne McCaffery, Michael J. Lyons, Kristen C. Jacobsen, and William S. Kremen
Application of Bayesian network structure learning to identify causal variant SNPs from resequencing data, Christopher E. Schlosberg, Tae-Hwi Schwantes-An, Weimin Duan, and Nancy L. Saccone
Mouse models of graft-versus-host disease: advances and limitations, Mark A. Schroder and John F. DiPersio
Deriving measures of intensive care unit antimicrobial use from computerized pharmacy data: Methods, validation, and overcoming barriers, David N. Schwartz, R Scott Evans, Bernard C. Camins, Yosef M. Khan, James F. Lloyd, Nadine Shehab, Kurt Stevenson, and Centers for Disease Control and Prevention Epicenter Program
Population dynamics and niche distribution of uropathogenic Escherichia coli during acute and chronic urinary tract infection, Drew J. Schwartz, Swaine L. Chen, Scott J. Hultgren, and Patrick C. Seed
Mixed infection with cagA positive and cagA negative strains of Helicobacter pylori lowers disease burden in the Gambia, Ousman Secka, Martin Antonio, Douglas E. Berg, Mary Tapgun, Christian Bottomley, Vivat Thomas, Robert Walton, Tumani Corrah, Julian E. Thomas, and Richard A. Adegbola
PCR-based genotyping of Helicobacter pylori of Gambian children and adults directly from biopsy specimens and bacterial cultures, Ousman Secka, Martin Antonio, Mary Tapgun, Douglas E. Berg, Christian Bottomley, Vivat Thomas, Robert Walton, Tumani Corrah, Richard A. Adegbola, and Julian E. Thomas
Integrase inhibitors effective against human T-cell leukemia virus type 1, Muhammad E. Seegulam and Lee Ratner
Integrase inhibitors effective against human T-cell leukemia virus type 1, Muhammad Esa Seegulam and Lee Ratner
Episodic memory retrieval, parietal cortex, and the default mode network: Functional and topographic analyses, Carlo Sestieri, Maurizio Corbetta, Gian Luca Romani, and Gordon L. Shulman
Serostatus disclosure among adults with HIV in the era of HIV therapy, Enbal Shacham, Eusebius Small, Nur Onen, Kate Stamm, and E. Turner Overton
Assessing the optimal definition of oligohydramnios associated with adverse neonatal outcomes, Anthony Shanks, Methodius Tuuli, Caren Schaecher, Anthony O. Odibo, and Roxane Rampersad
Evaluation of the toxicity of triamcinolone acetonide and dexamethasone sodium phosphate on human lens epithelial cells (HLE B-3), Ashish Sharma, Ashkan Pirouzmanesh, Jayaprakash Patil, M. F. Estrago-Franco, Leandro Cabral Zacharias, Usha P. Andley, M. Cristina Kenney, and Baruch D. Kuppermann
Primary somatosensory cortex in chronic low back pain – a 1H-MRS study, Neena K. Sharma, Kenneth McCarson, Linda Van Dillen, Angela Lentz, Talal Khan, and Carmen M. Cirstea
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival, Andrey S. Shaw, Suma Yaddanapudi, Mehmet M. Altintas, Andreas D. Kistler, Isabel Fernandez, Clemens C. Moller, Changli Wei, Vasil Peev, Jan B. Flesche, Anna-Lena Forst, Jing Li, Jaakko Patrakka, Zhijie Xiao, Florian Grahammer, and et al.
APOE4 allele disrupts resting state fMRI connectivity in the absence of amyloid plaques or decreased CSF Aβ42, Yvette I. Sheline, John C. Morris, Abraham Z. Synder, Joseph L. Price, Zhizi Yan, Gina D'Angelo, Collin Liu, Sachin Dixit, Tammie Benzinger, Anne Fagan, Alison Goate, and Mark A. Mintun
Sap transporter mediated import and subsequent degradation of antimicrobial peptides in Haemophilus, Catherine L. Shelton, Forrest K. Raffel, Wandy L. Beatty, Sara M. Johnson, and Kevin M. Mason
Enriching rare variants using family-specific linkage information, Gang Shi, Jeannette Simino, and Dabeeru C. Rao
Biomarkers predicting Alzheimer's disease in cognitively normal aging, Yong S. Shim and John C. Morris
Highwire regulates guidance of sister axons in the drosophila mushroom body, Jung Eun Shin and Aaron DiAntonio
Exploring patient-provider interactions in a Native American community, Vanessa Watts Simonds, Suzanne Christopher, Thomas D. Sequist, Graham A. Colditz, and Rima E. Rudd
A rapid communication from the AAPM Task Group 201: Recommendations for the QA of external beam radiotherapy data transfer. AAPM TG 201: Quality assurance of external beam radiotherapy data transfer, R. Alfredo Siochi, Peter Balter, Charles D. Bloch, Lakshmi Santanam, Kurt Blodgett, Bruce H. Curran, Martijn Engelsman, Wenzheng Feng, Jim Mechalakos, Dan Pavord, Tom Simon, Steven Sutlief, and X. Ronald Zhu
Evolutionarily divergent, unstable filamentous actin Is essential for gliding motility in spicomplexan parasites, Kristen M. Skillman, Karthikeyan Diraviyam, Asis Khan, Keliang Tang, David Sept, and L. David Sibley
Complete genome sequence of Treponema paraluiscuniculi, strain Cuniculi A: The loss of infectivity to humans is associated with genome decay, David Smajs, Marie Zobanikova, Michal Strouhal, Darina Cejkova, Shannon Dugan-Rocha, Petra Pospisilova, Steven J. Norris, Tom Albert, Xiang Qin, Kym Hallsworth-Pepin, Christian Buhay, Donna M. Muzny, Lei Chen, Richard A. Gibbs, and George M. Weinstock
Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans, Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, and Luigi Fontana
Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons, Erica Sodergren and et al
Video-rate fluorescence diffuse optical tomography for in vivo sentinel lymph node imaging, Metasebya Solomon, Brian R. White, Ralph E. Nothdruft, Walter Akers, Gail Sudlow, Adam T. Eggebrecht, Samuel Achilefu, and Joseph P. Culver
Coordinated increase in inhibitory and excitatory synapses onto retinal ganglion cells during development, Florentina Soto, Adam Bleckert, Renate Lewis, Yunhee Kang, Daniel Kerschensteiner, Ann Marie Craig, and Rachel OL Wong
A sensitive high-throughput assay for evaluating host-pathogen interactions in cryptococcus neoformans infection, Deepa Srikanta, Meng Yang, Matthew Williams, and Tamara L. Doering
Catalytic and non-catalytic roles for the Mono-ADP-Ribosyltransferase Arr in the mycobacterial DNA damage response, Christina L. Stallings, Linda Chu, Lucy X. Li, and Michael S. Glickman
CarD: A new RNA polymerase modulator in mycobacteria, Christina L. Stallings and Michael S. Glickman
Crohn disease: A current perspective on genetics, autophagy and immunity, Thaddeus S. Stappenbeck, John D. Rioux, Atsushi Mizoguchi, Tatsuya Saitoh, Alan Huett, Arlette Darfeuille-Michaud, Tom Wileman, Noboru Mizushima, Simon Carding, Shizuo Akira, Miles Parkes, and Ramnik J. Xavier
The [RNQ+] prion: A model of both functional and pathological amyloid, Kevin C. Stein and Heather L. true
Oral acyclovir suppression and neurodevelopment after neonatal herpes, Gregory Storch and et al
Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning, Melissa D. Stuchell-Brereton, Amanda Siglin, Jun Li, Jeffrey K. Moore, Shubbir Ahmed, John C. Williams, and John A. Cooper
RNA binding protein CUGBP2/CELF2 mediates curcumin- induced mitotic catastrophe of pancreatic cancer cells, Dharmalingam Subramaniam, Satish Ramalingam, David C. Linehan, Brian K. Dieckgraefe, Russell G. Postier, Courtney W. Houchen, Roy A. Jensen, and Shrikant Anant
Application of collapsing methods for continuous traits to the Genetic Analysis Workshop 17 exome sequence data, Yun Ju Sung, Treva K. Rice, and Dabeeru C. Rao
Changes in events alter how people remember recent information, Khena M. Swallow, Deanna M. Barch, Denise Head, Corey J. Maley, Derek Holder, and Jeffrey M. Zacks
Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo, Melissa Swiecki, Yaming Wang, William Vermi, Susan Gilfillan, Robert D. Schreiber, and Marco Colonna
Neural representation of temporal duration: coherent findings obtained with the “lossy integration” model, Olga V. Sysoeva, Marc Wittmann, and Jiri Wackermann
Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3beta independent of JNK activation, Katsuya Tanabe, Yang Liu, Syed D. Hasan, Sara C. Martinez, Corentin Cras-Meneur, Cris M. Welling, Ernesto Bernal-Mizrachi, Yukio Tanizawa, Christopher J. Rhodes, Erik Zmuda, Tsonwin Hai, Nada A. Abumrad, and M. Alan Permutt
Preschool onset attention-deficit/hyperactivity disorder: Course and predictors of stability over 24 months, Mini Tandon, Xuemei Si, and Joan Luby
Targeting protein-protein interactions for parasite control, Christina M. Taylor, Kerstin Fischer, Sahar Abubucker, Zhengyuan Wang, John Martin, Daojun Jiang, Marc Magliano, Marie-Noelle Rosso, Ben-Wen Li, Peter U. Fischer, and Makedonka Mitreva
Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis, Dick Terwel, Knut R. Steffensen, Philip B. Verghese, Markus P. Kummer, Jan-Åke Gustafsson, David M. Holtzman, and Michael T. Heneka
