The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2004

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Identification of a compensatory mutant (lpg2-REV) of Leishmania major able to survive as amastigotes within macrophages without LPG2-dependent glycoconjugates and its significance to virulence and immunization strategies, Gerald F. Spath, Lon-Fye Lye, Hiroaki Segawa, Salvatore J. Turco, and Stephen M. Beverley

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pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development, Natalie H. Stickle, Jacky Chung, Jeffery M. Klco, Richard P. Hill, William G. Kaelin Jr., and Michael Ohh

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Laparoscopic sacrocolpopexy for the correction of vaginal vault prolapse, Chandru P. Sundaram, Ramakrishna Venkatesh, Jaime Landman, and Carl G. Klutke

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Inhibition of aldose reductase by tannoid principles of Emblica officinalis: Implications for the prevention of sugar cataract, P. Suryanarayana, P. Anil Kumar, Megha Saraswat, J. Mark Petrash, and G. Bhanuprakash Reddy

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Motility of urease-deficient derivatives of Helicobacter pylori, Shumin Tan and Douglas E. Berg

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Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection, Pablo Tebas, Kevin Yarasheski, Keith Henry, Sherri Claxton, E. Kane, B. Bordenave Regions Hospital, Michael Klebert, and William G. Powderly

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RANKing c-Jun in osteoclast development, Steven L. Teitelbaum

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Gene prediction and verification in a compact genome with numerous small introns, Aaron E. Tenney, Randall H. Brown, Charles Vaske, Jennifer K. Lodge, Tamara L. Doering, and Michael R. Brent

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Substitution of HIV type 1 Nef with HTLV-1 p12, Tomonori Tsukahara and Lee Ratner

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Involvement of salmonella pathogenicity island 2 in the up-regulation of interleukin-10 expression in macrophages: role of protein kinase a signal pathway, Kei-ichi Uchiya, Eduardo A. Groisman, and Toshiaki Nikai

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Regulation of the Ysa type III secretion system of Yersinia enterocolitica by YsaE/SycB and YsrS/YsrR, Kimberly A. Walker and Virginia L. Miller

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Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome, John Wallis, Tina Graves, Dan Layman, Derek Albracht, Jonathon Davito, Tony Gaige, Kelly Mead, Jason Walker, Mandeep Sekhon, LaDeana Hillier, Wes Warren, Elaine Mardis, John D. McPherson, Richard Wilson, and et al

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Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures, Matthew J. Walter, John S. Park, Steven K. M. Lau, Xia Li, Andrew A. Lane, Rakesh Nagarajan, William D. Shannon, and Timothy J. Ley

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Role of natural killer cells in innate protection against lethal Ebola virus infection, Kelly L. Warfield, Jeremy G. Perkins, Dana L. Swenson, Emily M. Deal, Catharine M. Bosio, M. Javad Aman, Wayne M. Yokoyama, Howard A. Young, and Sina Bavari

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Detection of methicillin-resistant Staphylococcus aureus directly from nasal swab specimens by a real-time PCR assay, David K. Warren, Robert S. Liao, Lina R. Merz, Michael Eveland, and W. Michael Dunne Jr.

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Occurrence of co-colonization or co-infection with vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus in a medical intensive care unit, David K. Warren, Anand Nitin, and Cheri Hill

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Postexposure prophylaxis against varicella-zoster virus infection among recipients of hematopoietic stem cell transplant: Unresolved issues, David M. Weinstock, Michael Boeckh, Farid Boulad, Janet A. Eagan, Victoria J. Fraser, David K. Henderson, Trish M. Perl, Deborah Yokoe, and Kent A. Sepkowitz

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Replication of norovirus in cell culture reveals a tropism for dendritic cells and macrophages, Christiane E. Wobus, Stephanie M. Karst, Larissa B. Thackray, Kyeong-OK Chang, Stanislav V. Sosnovtsev, Gael Belliot, Anne Krug, Jason M. Mackenzie, Kim Y. Green, and Herbert W. Virgin IV

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Discs large (Dlg1) complexes in lymphocyte activation, Ramnik Xavier, Shahrooz Rabizadeh, Kazuhiro Ishiguro, Niko Andre, J. Bernabe Ortiz, Heather Wachtel, David G. Morris, Marco Lopez-Ilasaca, Albert C. Shaw, Wojciech Swat, and Brian Seed

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Latent class typology of nicotine withdrawal: genetic contributions and association with failed smoking cessation and psychiatric disorders, Hong Xian, Jeffrey F. Scherrer, Pamela A F Madden, Michael J. Lyons, Ming Tsuang, William R. true, and Seth A. Eisen

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Unveiling molecular scaffolds of the type IV secretion system, Hye-Jeong Yeo and Gabriel Waksman

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Fine needle aspiration of the thyroid: A cytohistologic correlation and study of discrepant cases, Lourdes R. Ylagan, Tunde Farkas, and Louis P. Dehner

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Yeast actin patches are networks of branched actin filaments, Michael E. Young, John A. Cooper, and Paul C. Bridgman

Submissions from 2003

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Genetic Analysis Workshop 13: Analysis of Longitudinal Family Data for Complex Diseases and Related Risk Factors, Laura Almasy, Christopher I. Amos, Joan E. Bailey-Wilson, Rita M. Cantor, Cashell E. Jaquish, Maria Martinez, Rosalind J. Neuman, Jane M. Olson, Lyle J. Palmer, Stephen S. Rich, M Anne Spence, and Jean W. MacCluer

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Risk factors for Stenotrophomonas maltophilia bacteremia in oncology patients: A case-control study, Anucha Apisarnthanarak, Jennie L. Mayfield, Teresa Garison, Patricia M. Mclendon, John F. DiPersio, Victoria J. Fraser, and Louis B. Polish

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Detection of Ehrlichia spp. in the Blood of wild white-tailed deer in Missouri by PCR assay and serologic analysis, Max Q. Arens, Allison M. Liddell, Gerald Buening, Monique Gaudreault-Keener, John W. Sumner, James A. Comer, Richard S. Buller, and Gregory A. Storch

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Differences in percutaneous injury patterns in a multi-hospital system, Hilary M. Babcock and Victoria Fraser

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Ventilator-associated pneumonia in a multi-hospital system: Differences in microbiology by location, Hilary M. Babcock, Jeanne E. Zack, Teresa Garrison, Ellen Trovillion, Marin H. Kollef, and Victoria J. Fraser

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Helicobacter pylori infection induces interleukin-8 receptor expression in the human gastric epithelium, Fredrik Backhed, Elisabeth Torstensson, Delphine Seguin, Agneta Richter-Dahlfors, and Bachra Rokbi

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Chaperone-subunit-usher interactions required for donor strand exchange during bacterial pilus assembly, Michelle M. Barnhart, Frederic G. Sauer, Jerome S. Pinkner, and Scott J. Hultgren

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Targeted inactivation of the IL-4 receptor α chain I4R motif tromotes allergic airway inflammation, Frank Blaeser, Paul J. Bryce, Nga Ho, Vidya Raman, Fatma Dedeoglu, Debra D. Donaldson, Raif S. Geha, Hans C. Oettgen, and Talal A. Chatila

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Pedicle subtraction osteotomy for the treatment of fixed sagittal imbalance, Keith H. Bridwell, Stephen J. Lewis, Lawrence G. Lenke, Christy Baldus, and Kathy Blanke

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Incorporation of gene-specific variability improves expression analysis using high-density DNA microarrays, Vikram Budhraja, Edward Spitznagel, W Timothy Schaiff, and Yoel Sadovsky

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Presence of active aliphatic amidases in Helicobacter species able to colonize the stomach, Stephanie Bury-Mone, Stephane Skouloubris, Catherine Dauga, Jean-Michel Thiberge, Daiva Dailidiene, Douglas E. Berg, Agnes Labigne, and Hilde De Reuse

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Cortactin is a component of clathrin-coated pits and participates in receptor-mediated endocytosis, Hong Cao, James D. Orth, Jing Chen, Shaun G. Weller, John E. Heuser, and Mark A. McNiven

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Impaired differentiation of osteoclasts in TREM-2–deficient individuals, Marina Cella, Cecilia Buonsanti, Carey Strader, Takayuki Kondo, Andrea Salmaggi, and Marco Colonna

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Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death, Louis K. Chang, Robert E. Schmidt, and Eugene M. Johnson Jr.

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Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression, M. A. Chellaiah, N. Kizer, R. Biswas, U. Alvarez, J. Strauss-Schoenberger, L. Rifas, S. R. Rittling, D. T. Denhardt, and K. A. Hruska

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Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding, Mei-Shya Chen, Christine E. Ryan, and Helen Piwnica-Worms

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Fugu ESTs: New Resources for Transcription Analysis and Genome Annotation, Melody S. Clark, Yvonne J.K. Edwards, Dan Peterson, Sandra W. Clifton, Amanda J. Thompson, Masahide Sasaki, Yutaka Suzuki, Kiyoshi Kikuchi, Shugo Watabe, Koichi Kawakami, Sumio Sugano, Greg Elgar, and Stephen L. Johnson

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Prevalence of the use of central venous access devices within and outside of the intensive care unit: Results of a survey among hospitals in the prevention epicenter program of the Centers for Disease Control and Prevention, Michael Climo, Dan Diekema, David K. Warren, Loreen A. Herwaldt, Trish M. Perl, Lance Peterson, Theresa Plaskett, Connie Price, Kent Sepkowitz, Steve Solomon, Jerry Tokars, Victoria J. Fraser, and Edward Wong

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Use of a random coefficient regression (RCR) model to estimate growth parameters, Jonathan Corbett, Aldi Kraja, Ingrid B. Borecki, and Michael A. Province

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Virulence genes and neutral DNA markers of Helicobacter pylori isolates from different ethnic communities of West Bengal, India, Simanti Datta, Santanu Chattopadhyay, G. Balakrish Nair, Asish K. Mukhopadhyay, Jabaranjan Hembram, Douglas E. Berg, Dhira Rani Saha, Asis Khan, Amal Santra, S. K. Bhattacharya, and Abhijit Chowdhury

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Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor, Dominique Davidson, Marcin Bakinowski, Matthew L. Thomas, Vaclav Horejsi, and Andre Veillette

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Dual function of Slit2 in repulsion and enhanced migration of trunk, but not vagal, neural crest cells, Maria Elena De Bellard, Yi Rao, and Marianne Bronner-Fraser

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A critical role for induced IgM in the protection against West Nile virus infection, Michael S. Diamond, Elizabeth M. Sitati, Lindzy D. Friend, Stephen Higgs, Bimmi Shrestha, and Michael Engle

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Sensitivity to changes in disability after stroke: A comparison of four scales useful in clinical trials, Alexander W. Dromerick, Dorothy F. Edwards, and Michael N. Diringer

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The rovA mutant of Yersinia enterocolitica displays differential degrees of virulence depending on the route of infection, Peter H. Dube, Scott A. Handley, Paula A. Revell, and Virginia L. Miller

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Forssman synthetase expression results in diminished Shiga toxin susceptibility: A role for glycolipids in determining host-microbe interactions, Sean P. Elliott, Min Yu, Huaijin Xu, and David B. Haslam

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YmoA negatively regulates expression of invasin from Yersinia enterocolitica, Damon W. Ellison, Briana Young, Kristin Nelson, and Virginia L. Miller

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Gating Mechanism of KATP Channels: Function Fits Form, Decha Enkvetchakul and Colin G. NIchols

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Dynamic changes in the osteoclast cytoskeleton in response to growth factors and cell attachment are controlled by beta-3 integrin, Roberta Faccio, Deborah V. Novack, Alberta Zallone, F. Patrick Ross, and Steven L. Teitelbaum

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Regulation of fyn through translocation of activated Lck into lipid rafts, Dominik Filipp, Jenny Zhang, Bernadine L. Leung, Andrey Shaw, Steven D. Levin, André Veillette, and Michael Julius

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Chromosomal expression of the Haemophilus influenzae hap autotransporter allows fine-tuned regulation of adhesive potential via inhibition of intermolecular autoproteolysis, Doran L. Fink and Joseph W. St. Geme III

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Software for automated analysis of DNA fingerprinting gels, Daniel R. Fuhrmann, Martin I. Krzywinski, Readman Chiu, Parvaneh Saeedi, Jacqueline E. Schein, Ian E. Bosdet, Asif Chinwalla, LaDeana W. Hillier, Robert H. Waterston, John D. McPherson, Steven J.M. Jones, and Marco A. Marra

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Vav1/2/3-null mice define an essential role for vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells, Keiko Fujikawa, Ana V. Miletic, Frederick W. Alt, Roberta Faccio, Tracie Brown, Jeremy Hoog, Jessica Fredericks, Shinzo Nishi, Shirly Mildiner, Sheri L. Moores, Joan Brugge, Fred S. Rosen, and Wojciech Swat

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Role of cytokines and major histocompatibility complex restriction in mouse resistance to infection with a natural Recombinant strain (Type I-III) of Toxoplasma gondii, Blima Fux, Cibele V. Rodrigues, Ricardo W. Portela, Neide M. Silva, Chunlei Su, David Sibley, Ricardo W. A. Vitor, and Ricardo T. Gazzinelli

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Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival, Lian-Yong Gao, Richard Groger, Jeffery S. Cox, Stephen M. Beverley, Elise H. Lawson, and Eric J. Brown

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Mammalian GGAs act together to sort mannose 6-phosphate receptors, Pradipta Ghosh, Janice Griffith, Hans J. Geuze, and Stuart Kornfeld

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AP-1 binding to sorting signals and release from clathrin-coated vesicles is regulated by phosphorylation, Pradipta Ghosh and Stuart Kornfeld

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Down-regulation of CD46 by piliated neisseria gonorrhoeae, Darcy B. Gill, Michael Koomey, Janne G. Cannon, and John P. Atkinson

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Tyrosine-phosphorylated and nonphosphorylated isoforms of α-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions, R. Mark Grady, Mohammed Akaaboune, Alexander L. Cohen, Margaret M. Maimone, Jeff W. Lichtman, and Joshua R. Sanes

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The risk of a new retinal break or detachment following cataract surgery in eyes that had undergone repair of phakic break or detachment: A hypothesis of a causal relationship to cataract surgery, M. Gilbert Grand

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Risk of hospital-acquired legionnaires' disease in cities using monochloramine versus other water disinfectants, James D. Heffelfinger, Jacob L. Kool, Scott Fridkin, Victoria J. Fraser, Jeffrey Hageman, Jospeh Carpenter, and Cynthia G. Whitney

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Differential requirement for the nonhelical tailpiece and the C terminus of the myosin rod in Caenorhabditis elegans muscle, Pamela E. Hoppe, Rebecca C. Andrews, and Payal D. Parikh

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PCAP: A Whole-Genome Assembly Program, Xiaoqiu Huang, Jianmin Wang, Srinivas Aluru, Shiaw-Pyng Yang, and LaDeana Hillier

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T-cadherin-mediated cell growth regulation involves G2 phase arrest and requires p21(CIP1/WAF1) expression, Zhi-yong Huang, YanLi Wu, Nicole Hedrick, and David H. Gutmann

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Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling, Tobias B. Huber, Bjorn Hartleben, Jeong Kim, Miriam Schmidts, Bernhard Schermer, Alexander Keil, Lotti Egger, Rachel L. Lecha, Christoph Borner, Hermann Pavenstadt, Andrey S. Shaw, Gerd Walz, and Thomas Benzing

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Highly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain, Kirby D. Johnson, Jeffrey A. Grass, Changwon Park, Hogune Im, Kyunghee Choi, and Emery H. Bresnick

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Stability of repetitive-sequence PCR patterns with respect to culture age and subculture frequency, Hyunseok Peter Kang and W. Michael Dunne

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Eval: A software package for analysis of genome annotations, Evan Keibler and Michael R. Brent

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Cluster of type IV secretion genes in Helicobacter pylori's plasticity zone, Dangeruta Kersulyte, Billie Velapatiño, Asish K. Mukhopadhyay, Lizbeth Cahuayme, Alejandro Bussalleu, Juan Combe, Robert H. Gilman, and Douglas E. Berg

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Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane, Yamato Kikkawa, Ismo Virtanen, and Jeffrey H. Miner

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Specificity and regulation of DNA binding by the yeast glucose transporter gene repressor Rgt1, Jeong-Ho Kim, Jeffrey Polish, and Mark Johnston

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RSEARCH: Finding homologs of single structured RNA sequences, Robert J. Klein and Sean R. Eddy

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Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice, Masaya Kobayashi, Mi-Na Kweon, Hirotaka Kuwata, Robert D. Schreiber, Hiroshi Kiyono, Kiyoshi Takeda, and Shizuo Akira

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Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells, Anne Krug, Ravi Veeraswamy, Andrew Pekosz, Osami Kanagawa, Emil R. Unanue, Marco Colonna, and Marina Cella

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Set2-catalyzed methylation of histone H3 represses basal expression of GAL4 in Saccharomyces cerevisiae, Joseph Landry, Ann Sutton, Tina Hesman, Jinrong Min, Rui-Ming Xu, Mark Johnston, and Rolf Sternglanz

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Antiadhesive role of apical decay-accelerating factor (CD55) in human neutrophil transmigration across mucosal epithelia, Donald W. Lawrence, Walter J. Bruyninckx, Nancy A. Louis, Douglas M. Lublin, Gregory L. Stahl, Charles A. Parkos, and Sean P. Colgan

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The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast, Wei-Lih Lee, Jessica R. Oberle, and John A. Cooper

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A high performance test of differential gene expression for oligonucleotide arrays, William J. Lemon, Sandya Liyanarachchi, and Ming You

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Predominance of Ehrlichia ewingii in Missouri dogs, Allison M. Liddell, Steven L. Stockham, Michael A. Scott, John W. Summer, Christopher D. Paddock, Monique Gaudreault-Keener, Max Q. Arens, and Gregory A. Storch

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Denaturing high-performance liquid chromatography for detecting and typing genital Human Papillomavirus, Jianduan Li, Daniela S. Gerhard, Zhengyan Zhang, Phillis C. Huettner, Jason Wright, Loan Nguyen, Danielle Lu, and Janet S. Rader

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Reduction of a dislocation of the hip due to developmental dysplasia: Implications for the need for future surgery, Scott J. Luhmann, George S. Bassett, J. Eric Gordon, Mario Schootman, and Perry L. Schoenecker

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Multimeric threading-based prediction of protein–protein interactions on a genomic scale: Application to the Saccharomyces cerevisiae proteome, Long Lu, Adrian K. Arakaki, Hui Lu, and Jeffrey Skolnick

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Trigger factor-mediated prolyl isomerization influences maturation of the Streptococcus pyogenes cysteine protease, William R. Lyon and Michael G. Caparon

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Galactokinase gene mutations and age-related cataract. Lack of association in an Italian population, Giovanni Maraini, J. Fielding Hejtmancik, Alan Shiels, Donna S. Mackay, Raffaella Aldigeri, Xiao D. Jiao, Sally L. Williams, Robert D. Sperduto, and George Reed

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Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions, Sandra S. McAllister, Michelle Becker-Hapak, Giuseppe Pintucci, Michele Pagano, and Steven F. Dowdy

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Analysis and functional classification of transcripts from the nematode Meloidogyne incognita, James P. McCarter, Makedonka Dautova Mitreva, John Martin, Mike Dante, Todd Wylie, Uma Rao, Deana Pape, Yvette Bowers, Brenda Theising, Claire V. Murphy, Andrew P. Kloek, Brandi J. Chiapelli, Sandra W. Clifton, David McK Bird, and Robert H. Waterston

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Immune-deficient mouse models for analysis of human stem cells, Todd E. Meyerrose, Phillip Herrbrich, David A. Hess, and Jan A. Nolta

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Efficient high-throughput resequencing of genomic DNA, Raymond D. Miller, Shenghui Duan, Elizabeth G. Lovins, Ellen F. Kloss, and Pui-Yan Kwok

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Targeted chemical disruption of clathrin function in living cells, Howard S. Moskowitz, John Heuser, Timothy E. McGraw, and Timothy A. Ryan

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Effect of Achilles tendon lengthening on neuropathic plantar ulcers: A randomized clinical trial, Michael J. Mueller, David R. Sinacore, Mary Kent Hastings, Michael J. Strube, and Jeffrey E. Johnson

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The fdxA ferredoxin gene can down-regulate frxA nitroreductase gene expression and is essential in many strains of Helicobacter pylori, Asish K. Mukhopadhyay, Jin-Yong Jeong, Daiva Dailidiene, Paul S. Hoffman, and Douglas E. Berg

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Accelerated fat absorption in intestinal alkaline phosphatase knockout mice, Sonoko Narisawa, Lei Huang, Arata Iwasaki, Hideaki Hasegawa, David H. Alpers, and Jose Luis Millan

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Role of RopB in growth phase expression of the SpeB cysteine protease of Streptococcus pyogenes, Melody N. Neely, William R. Lyon, Donna L. Runft, and Michael Caparon

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Human intestinal epithelial and smooth muscle cells are potent producers of IL-6, Edmond K. Ng, Ninder Panesar, Walter E. Longo, Marc J. Shapiro, Donald L. Kaminski, Kym C. Tolman, and John E. Mazuski

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Lens connexins α3Cx46 and α8Cx50 interact with zonula occludens protein-1 (ZO-1), Peter A. Nielsen, Amos Baruch, Valery I. Shestopalov, Ben N.G. Giepmans, Irene Dunia, E. Lucio Benedetti, and Nalin M. Kumar

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The IκB function of NF-κB2 p100 controls stimulated osteoclastogenesis, Deborah Veis Novack, Li Yin, Amanda Hagen-Stapleton, Robert D. Schreiber, David V. Goeddel, F. Patrick Ross, and Steven L. Teitelbaum

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Inhibition of stress-inducible kinase pathways by tumorigenic mutant p53, Yoichi Ohiro, Anny Usheva, Shinichiro Kobayashi, Shannon L. Duffy, Regan Nantz, David Gius, and Nobuo Horikoshi