The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2007
Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk, Luigi Fontana, Timothy E. Meyer, Samuel Klein, and John O. Holloszy
Genetics of body mass stability and risk for chronic disease: A 28-year longitudinal study, Carol E. Franz, MIchael D. Grant, Kristen C. Jacobson, William S. Kremen, Seth A. Eisen, Hong Xian, James Romeis, Heather Thompson-Brenner, and Michael J. Lyons
ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity, Rodrigo A. Fuentealba, Maria Ines Barría, Jiyeon Lee, Judy Cam, Claudia Araya, Claudia A. Escudero, Nibaldo C. Inestrosa, Francisca C. Bronfman, Guojun Bu, and Maria-Paz Marzolo
Common genetic risk of major depression and nicotine dependence: The contribution of antisocial traits in a United States veteran male twin cohort, Qiang Fu, Andrew C. Heath, Kathleen K. Bucholz, Michael J. Lyons, Ming T. Tsuang, William R. true, and Seth A. Eisen
Toxoplasma gondii strains defective in oral transmission are also defective in developmental stage differentiation, Blima Fux, Julie Nawas, Asis Khan, Darcy B. Gill, Chunlei Su, and L David Sibley
Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation, Corinne K. Garofalo, Thomas M. Hooton, Steven M. Martin, Walter E. Stamm, Joseph J. Palermo, Jeffrey I. Gordon, and Scott J. Hultgren
Identification of a novel polyomavirus from patients with acute respiratory tract infections, Anne M. Gaynor, Michael D. Nissen, David M. Whiley, Ian M. Mackay, Stephen B. Lambert, Guang Wu, Daniel C. Brennan, Gregory A. Storch, Theo P. Sloots, and David Wang
Proposed definitions of bipolar I disorder episodes and daily rapid cycling phenomena in preschoolers, school-aged children, adolescents, and adults, Barbara Geller, Rebecca Tillman, and Kristine Bolhofner
NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat, Antonino Germanò, Mariella Caffo, Filippo Flavio Angileri, Francesca Arcadi, Jennifer Newcomb, Gerardo Caruso, Francesco Meli, Jose A. Pineda, Stephen B. Lewis, Kevin K. W. Wang, Placido Bramanti, Chiara Costa, and Ronald L. Hayes
Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse, Emanuele Giurisato, Marina Cella, Toshiyuki Takai, Tomohiro Kurosaki, Yungfeng Feng, Gegory D. Longmore, Marco Colonna, and Andrey S. Shaw
Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency: A case report, Priya K. Gopalan, John C. Clohisy, Amanda F. Cashen, and Charles S. Eby
Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCγ2 signaling axis in mice, Daniel B. Graham, Charles M. Robertson, Jhoanne Bautista, Francesca Mascarenhas, M. Julia Diacovo, Vivianne Montgrain, Siu Kit Lam, Viviana Cremasco, W. Michael Dunne, Roberta Faccio, Craig M. Coopersmith, and Wojciech Swat
An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells, Daniel B. Graham, Linda M. Stephenson, Siu Kit Lam, Karry Brim, Hyang Mi Lee, Jhoanne Bautista, Susan Gilfillan, Shreeram Akilesh, Keiko Fujikawa, and Wojciech Swat
A high-resolution map of segmental DNA copy number variation in the mouse genome, Timothy A. Graubert, Patrick Cahan, Deepa Edwin, Rebecca R. Selzer, Todd A. Richmond, Peggy S. Eis, William D. Shannon, Xia Li, Howard L. McLeod, James M. Cheverud, and Timothy J. Ley
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome, Tina Graves, Robert Fulton, Elaine R. Mardis, Richard K. Wilson, and et al
Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia, Mitchell H. Grayson, Dorothy Cheung, Michelle M. Rohlfing, Robert Kitchens, Daniel E. Spiegel, Jennifer Tucker, John T. Battaile, Yael Alevy, Le Yan, Eugene Agapov, Edy Y. Kim, and Michael J. Holtzman
Calpain activation impairs neuromuscular transmission in a mouse model of the slow-channel myasthenic syndrome, Jason S. Groshong, Melissa J. Spencer, Bula J. Bhattacharyya, Elena Kudryashova, Bhupinder P.S. Vohra, Roberto Zayas, Robert L. Wollmann, Richard J. Miller, and Christopher M. Gomez
Stable preanaphase spindle positioning requires Bud6p and an apparent interaction between the spindle pole bodies and the neck, Brian K. Haarer, Astrid Hoes Helfant, Scott A. Nelson, John A. Cooper, and David C. Amberg
E2F8 is a nonreceptor activator of heterotrimeric G proteins, Ian S. Hagemann, Kirk D. Narzinski, and Thomas J. Baranski
Organogenesis of kidney and endocrine pancreas: The window opens, Marc R. Hammerman
Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D, Kevan L. Hartshorn, Mitchell R. White, Tesfaldet Tecle, Ida Tornoe, Grith L. Sorensen, Erika C. Crouch, and Uffe Holmskov
Large scale gene expression profiles of regenerating inner ear sensory epithelia, R. D. Hawkins, Stavros Bashiardes, Kara E. Powder, Samin A. Sajan, Veena Bhonagiri, David M. Alvarado, Judith Speck, Mark E. Warchol, and Michael Lovett
Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B, Coy D. Heldermon, Anne K. Henning, Kevin K. Ohlemiller, Judith M. Ogilvie, Erik D. Herzog, Annalisa Breidenbach, Carole Vogler, David F. Wozniak, and Mark S. Sands
Comparison of C. elegans and C. briggsae genome sequences reveals extensive conservation of chromosome organization and synteny, LaDeana W. Hiller, Raymond D. Miller, Scott E. Baird, Asif Chinwalla, Lucinda A. Fulton, Daniel C. Koboldt, and Robert H. Waterston
Linkage and association analyses of principal components in expression data, Anthony L. Hinrichs, Robert Culverhouse, Carol H. Jin, and Brian K. Suarez
Haplotyping a quantitative trait with a high-density map in experimental crosses, Wei Hou, John Stephen F. Yap, Song Wu, Tian Liu, James M. Cheverud, and Rongling Wu
The cis-regulatory logic of the mammalian photoreceptor transcriptional network, Timothy H. Hsiau, Claudiu Diaconu, Connie A. Myers, Jongwoo Lee, Constance L. Cepko, and Joseph C. Corbo
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Craig H. Bassing, Tej K. Pandita, and Barry P. Sleckman
Genetic and pharmacological factors that influence reproductive aging in nematodes, Stacie E. Hughes, Kimberley Evason, Chengjie Xiong, and Kerry Kornfeld
Gene duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a, Keith A. Hultman, Nathan Bahary, Leonard I. Zon, and Stephen L. Johnson
The Par-1/MARK family of protein kinases: From polarity to metabolism, Jonathan Hurov and Helen Piwnica-Worms
Changing human visual field organization from early visual to extra-occipital cortex, Anthony I. Jack, Gaurav H. Patel, Serguei V. Astafiev, Abraham Z. Snyder, Erbil Akbudak, Gordon L. Shulman, and Maurizio Corbetta
Genomic and gene regulatory signatures of cryptozoic adaptation: Loss of blue sensitive photoreceptors through expansion of long wavelength-opsin expression in the red flour beetle Tribolium castaneum, Magdalena Jackowska, Riyue Bao, Zhenyi Liu, Elizabeth C. McDonald, Tiffany A. Cook, and Markus Friedrich
Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing, Verena Jantsch, Lois Tang, Pawel Pasierbek, Alexandra Penkner, Sudhir Nayak, Antoine Baudrimont, Tim Schedl, Anton Gartner, and Josef Loidl
Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: Applications in diagnostic imaging and therapy, Hiroyuki Kashiwagi, Jonathan E. McDunn, Peter O. Simon Jr, Peter S. Goedegebuure, Jinbin Xu, Lynne Jones, Katherine Chang, Fabian Johnston, Kathryn Trinkaus, Richard S. Hotchkiss, Robert H. Mach, and William G. Hawkins
Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae, Thomas E. Kehl-Fie and Joseph W. St. Geme III
Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice, Jennifer Kelly, Aslam Ali Khan, Jiyi Yin, Thomas A. Ferguson, and Rajendra S. Apte
Pancreatitis following Olanzapine Therapy: A Report of Three Cases, Thomas A. Kerr, Sreenivasa Jonnalagadda, Chandra Prakash, and Riad Azar
Cell stress induced by the parkinsonian mimetic, 6-hydroxydopamine, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation, Jeong Sook Kim-Han and Karen L. O'Malley
Rheumatoid arthritis, item response theory, Blom transformation, and mixed models, Aldi T. Kraja, Jon Corbett, An Ping, Rosa S. Lin, Petra A. Jacobsen, Michael Crosswhite, Ingrid B. Borecki, and Michael A. Province
Circumstances of patient falls and injuries in 9 hospitals in a midwestern healthcare system, Melissa J. Krauss, Sheila L. Nguyen, Wm. Claiborne Dunagan, Stanley Birge, Eileen Costantinou, Shirley Johnson, Barbara Caleca, and Victoria J. Fraser
Polyamine permeation and rectification of kir4.1 channels, Yuri V. Kucheryavykh, Wade L. Pearson, Harley T. Kurata, Misty J. Eaton, Serguei N. Skatchkov, and Colin G. Nichols
The role of the cytoplasmic pore in inward rectification of Kir2.1 channels, Harley T. Kurata, Wayland W. Cheng, Christine Arrabit, Paul A. Slesinger, and Colin G. Nichols
Continued use of an integrated meter with electronic logbook maintains improvements in glycemic control beyond a randomized, controlled trial, Lori M. B. Laffel, William C. Hsu, Janet B. McGill, Luigi Meneghini, and Lisa K. Volkening
The bandit, a new DNA transposon from a hookworm— possible horizontal genetic transfer between host and parasite, Thewarach Laha, Alex Loukas, Supatra Wattanasatitarpa, Jenjira Somprakhon, Nonglack Kewgrai, Paiboon Sithithaworn, Sasithorn Kaewkes, Makedonka Mitreva, and Paul J. Brindley
Targeted discovery of novel human exons by comparative genomics, Laura Langton, Michael Stevens, Charles L.G. Comstock, Michael R. Brent, and et al
The 14-3-3τ phosphoserine-binding protein is required for cardiomyocyte survival, Jeffrey M. C. Lau, Xiaohua Jin, Jie Ren, Joan Avery, Brian J. DeBosch, Ilya Treskov, Traian S. Lupu, Attila Kovacs, Carla Weinheimer, and Anthony J. Muslin
Yersiniabactin is a virulence factor for Klebsiella pneumoniae during pulmonary infection, Matthew S. Lawlor, Christopher O'Connor, and Virginia L. Miller
Clostridium difficile in the intensive care unit: Epidemiology, costs, and colonization pressure, Steven J. Lawrence, Laura A. Puzniak, Brooke N. Shadel, Kathleen N. Gillespie, Marin H. Kollef, and Linda M. Mundy
Comparative analysis of the regulation of rovA from the pathogenic Yersiniae, Matthew B. Lawrenz and Virginia L. Miller
Evaluation of a novel chromogenic agar medium for isolation and differentiation of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis isolates, Nathan A. Ledeboer, Kingshuk Das, Michael Eveland, Celine Roger-Dalbert, Sandrine Mailler, Sonia Chatellier, and William Michael Dunne
Prevalence of cervical spine stenosis: Anatomic study in cadavers, Michael J. Lee, Ezequiel H. Cassinelli, and K. Daniel Riew
A little stress is good: IFN-γ, demyelination, and multiple sclerosis, Jason R. Lees and Anne H. Cross
Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli, Yvonne M. Lee, Karen W. Dodson, and Scott J. Hultgren
Management of juvenile idiopathic scoliosis, Lawrence G. Lenke and Matthew B. Dobbs
Calmodulin kinase II inhibition enhances ischemic preconditioning by augmenting ATP-sensitive K+ current, Jingdong Li, Celine Marionneau, Olha Koval, Leonid Zingman, Peter J. Mohler, Jeanne M. Nerbonne, and Mark E. Anderson
PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancer, W. T. Lim, W. H. Zhang, C. R. Miller, J. W. Watters, F. Gao, A. Viswanathan, R Govindan, and H. L. McLeod
Vascular injury from an arterial closure device, Jeffrey P. C. Lin, Brian G. Rubin, and William D. Middleton
Large-scale in silico mapping of complex quantitative traits in inbred mice, Pengyuan Liu, Haris Vikis, Yan Lu, Daolong Wang, and Ming You
Functional association of Sun1 with nuclear pore complexes, Qian Liu, Nelly Pante, Tom Misteli, Mohamed Elsagga, Melissa Crisp, Didier Hodzic, Brian Burke, and Kyle J. Roux
Acrochordon-like basal cell carcinomas in patients with basal cell nevus syndrome, David N. Lortscher, Roberta D. Sengelmann, and Shawn B. Allen
Contribution of invariant residues to the function of Rgg family transcription regulators, Jennifer Loughman and Michael G. Caparon
Diffusion tensor imaging predicts hyperacute spinal cord injury severity, David N. Loy, Joong Hee Kim, Mingqiang Xie, Robert E. Schmidt, Kathryn Trinkaus, and Sheng-Kwei Song
Psychotropic prescriptions in a sample including both healthy and mood and disruptive disordered preschoolers: relationships to diagnosis, impairment, prescriber type, and assessment methods, Joan L. Luby, Melissa Meade Stalets, and Andy C. Belden
Three clinical cases of DSM-IV mania symptoms in preschoolers, Joan Luby, Mini Tandon, and Ginger Nicol
Ivermectin resistance in Onchocerca volvulus: Toward a genetic basis, Sara Lustigman and James P. McCarter
Common human cancer genes discovered by integrated gene-expression analysis, Yan Lu, Yijun Yi, Pengyuan Liu, Weidong Wen, Michael James, Daolong Wang, and Ming You
Psychometric properties of DSM assessments of illicit drug abuse and dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), M. T. Lynskey and A. Agrawal
Mutations in α-tubulin confer dinitroaniline resistance at a cost to microtubule function, Christopher Ma, Catherine Li, Lakshmi Ganesan, Jean Oak, Susan Tsai, David Sept, and Naomi S. Morrissette
Clamping the Mec1/ATR checkpoint kinase into action, Jerzy Majka and Peter M.J. Burgers
Case-control study of surgical site infections associated with pacemakers and implantable cardioverter-defibrillators, Jonas Marschall, Diane Hopkins-Broyles, Marilyn Jones, Victoria J. Fraser, and David K. Warren
Catheter-associated bloodstream infections in general medical patients outside the intensive care unit: A surveillance study, Jonas Marschall, Carole Leone, Marilyn Jones, Deborah Nihill, Victoria J. Fraser, and David K. Warren
Regulation of KATP channel expression and activity by the SUR1 Nucleotide Binding Fold 1, Ricard Masia, George Caputa, and Colin G. Nichols
Nectin-like proteins mediate axon-Schwann cell interactions along the internode and are essential for myelination, Patrice Maurel, Steven Einheber, Jolanta Galinska, Pratik Thaker, Isabel Lam, Marina B. Rubin, Steven S. Scherer, Yoshinuri Murakami, David H. Gutmann, and James L. Salzer
Preparation of antidepressants for use in preclinical research, Jonathan E. McConathy, Catherine Capello, Nachwa Jarkas, Zachary N. Stowe, and Michael J. Owens
Whole-mount techniques to evaluate subepithelial cellular populations in the adult mouse intestine, Keely G. McDonald and Rodney D. Newberry
Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4, Michael D. McLellan, Yumi Kasai, Tracie L. Milner, Ginger A. Fewell, Lucinda L. Fulton, Elaine R. Mardis, Richard K. Wilson, and et al.
PI3K(p110α) inhibitors as anti-cancer agents: Minding the heart, Julie R. McMullen and Patrick Y. Jay
Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model, Samuel G. Melendez-Lopez, Scott Herdman, Ken Hirata, Min-Ho Choi, Youngchool Choe, Charles Craik, Conor R. Caffrey, Elisabeth Hansell, Jianhua Guo, Samuel L. Stanley Jr., Bibiana Chavez-Munguia, Yen Ting Chen, William R. Roush, James McKerrow, and et al.
Health care-associated pneumonia and community-acquired pneumonia: A single-center experience, Scott T. Micek, Katherine E. Kollef, Richard M. Reichley, Nareg Roubinian, and Marin H. Kollef
Addition of vasopressin to norepinephrine as independent predictor of mortality in patients with refractory septic shock: An observational study, Scott T. Micek, Poorvi Shah, James M. Hollands, Rina A. Shah, William D. Shannon, and Marin H. Kollef
Exploring the inter-relationship of smoking age-at-onset, cigarette consumption and smoking persistence: Genes or environment?, Katherine I. Morley, Michael T. Lynskey, Pamela A F Madden, Susan A. Treloar, Andrew C. Heath, and Nicholas G. Martin
Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model, John D. Morrey, Venkatraman Siddharthan, Aaron L. Olsen, Hong Wang, Justin G. Julander, Jeffery O. Hall, Hua Li, Jeffrey L. Nordstrom, Scott Koenig, Syd Johnson, and Michael S. Diamond
Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease, Odity Mukherjee, John SK Kauwe, Kevin Mayo, John C. Morris, and Alison M. Goate
Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii, Kisaburo Nagamune, Wandy L. Beatty, and L. David Sibley
Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis, Kisaburo Nagamune, Silvia N.J. Moreno, and L. David Sibley
MultiCode-PLx system for multiplexed detection of seventeen respiratory viruses, Frederick S. Nolte, David J. Marshall, Christopher Rasberry, Sabina Schievelbein, Grier G. Banks, Gregory A. Storch, Max Q. Arens, Richard S. Buller, and James R. Prudent
Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells, Alex S. Nord, Karen Vranizan, Whittemore Tingley, Alexander C. Zambon, Kristina Hanspers, Loren G. Fong, Yan Hu, Peter Bacchetti, Thomas E. Ferrin, Patricia C. Babbitt, Scott W. Doniger, William C. Skarnes, Stephen G. Young, and Bruce R. Conklin
Rapid maturation of effector T cells in tumors, but not lymphoid organs, during tumor regression, Lyse A. Norian and Paul M. Allen
Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment, Carol S. North, Barry A. Hong, and David H. Alpers
Phylogenetic diversity and microsphere array-based genotyping of human pathogenic fusaria, including isolates from the multistate contact lens-associated U.S. keratitis outbreaks of 2005 and 2006, Kerry O'Donnell, Brice A. Sarver, Mary Brandt, Douglas C. Chang, Judith Noble-Wang, Benjamin J. Park, Deanna A. Sutton, Lynette Benjamin, Mark Lindsley, Arvind Padhye, David M. Geiser, and Todd J. Ward
Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks, Olanrewaju Okusanya, Alan Forrest, Robin DiFrancesco, Sanela Bilic, Susan Rosenkranz, Michael F. Para, Elizabeth Adams, Kevin E. Yarasheski, Richard C. Reichman, Gene D. Morse, and ACTG 5043 Protocol Team
Shigella flexneri phagosomal escape is independent of invasion, Susanne Paetzold, Sebastian Lourido, Barbel Raupach, and Arturo Zychlinsky
MAGED2: A novel p53-dissociator, Chris Papageorgio, Rainer Brachmann, Jue Zeng, Robert Culverhouse, Wanghai Zhang, and Howard McLeod
The association of the activation-inducible tumor necrosis factor receptor and ligand with lumbar disc hermiation, Moon-Soo Park, Hwan-Mo Lee, Soo-Bong Hahn, Seong-Hwan Moon, Yung-Tae Kim, Choon-Sung Lee, Hyo-Won Jung, Byoung-Se Kwon, and K. Daniel Riew
Site-1 protease is essential for endochondral bone formation in mice, Debabrata Patra, Xiaoyun Xing, Sherri Davies, Jennifer Bryan, Carl Franz, Ernst B. Hunziker, and Linda J. Sandell
Toward an understanding of risk factors for anorexia nervosa: A case-control study, K. M. Pike, A. Hilbert, D. E. Wilfley, C. G. Fairburn, F. A. Dohm, B. T. Walsh, and R. Striegel-Moore
Clinical significance of αII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury, Jose A. Pineda, Stephen B. Lewis, Alex B. Valadka, Linda Papa, H. Julia Hannay, Shelley C. Heaton, Jason A. Demery, Ming Cheng Liu, Jada M. Aikman, Veronica Akle, Gretchen M. Brophy, Joseph J. Tepas III, Kevin K. W. Wang, Claudia S. Robertson, and Ronald L. Hayes
Genetic and environmental factors affecting self-esteem from age 14 to 17: A longitudinal study of Finnish twins, Anu Raevuori, Danielle M. Dick, Anna Keski-Rahkonen, Lea Pulkkinen, Richard J. Rose, Aila Rissanen, Jaakko Kaprio, Richard J. Viken, and Karri Silventoinen
Intracellular mediators of transforming growth factor β superfamily signaling localize to endosomes in chicken embryo and mouse lenses in vivo, Ramya Rajagopal, Shunsuke Ishii, and David C. Beebe
