The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2006

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Current concepts review: Management of elbow osteoarthritis, Gregory D. Gramstad and Leesa M. Galatz

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Chemokine signaling regulates apoptosis as well as immune cell traffic in host defense, Mitchell H. Grayson and Michael J. Holtzman

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Genetic variation in the zebrafish, Victor Guryev, Marco J. Koudijs, Eugene Berezikov, Stephen L. Johnson, Ronald H.A. Plasterk, Fredericus J.M. Van Eeden, and Edwin Cuppen

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Harnessing preclinical mouse models to inform human clinical cancer trials, David H. Gutmann, Kim Hunter-Schaedle, and Kevin M. Shannon

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Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: Results from CALGB 9342, Lyndsay N. Harris, Gloria Broadwater, Nancy U. Lin, Alexander Miron, Stuart J. Schnitt, David Cowan, Jonathan Lara, Ira Bleiweiss, Donald Berry, Matthew Ellis, Daniel F. Hayes, Eric P. Winer, and Lynn Dressler

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Mechanistic insights into the regulation of the spermatogonial stem cell niche, Rex A. Hess, Paul S. Cooke, Marie-Claude Hofmann, and Kenneth M. Murphy

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Lysosomal phospholipase A2 and phospholipidosis, Miki Hiraoka, Akira Abe, Ye Lu, Kui Yang, Xianlin Han, Richard Gross, and James A. Shayman

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Elastin fragments drive disease progression in a murine model of emphysema, A. McGarry Houghton, Pablo A. Quintero, David L. Perkins, Dale K. Kobayashi, Diane G. Kelley, Luiz A. Marconcini, Robert P. Mecham, Robert M. Senior, and Steven D. Shapiro

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Application of a superword array in genome assembly, Xiaoqiu Huang, Shiaw-Pyng Yang, Asif T. Chinwalla, LaDeana W. Hillier, Patrick Minx, Elaine R. Mardis, and Richard K. Wilson

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Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin, Tobias B. Huber, Christopher Kwoh, Hui Wu, Katsuhiko Asanuma, Markus Gödel, Björn Hartleben, Ken J. Blumer, Jeffrey H. Miner, Peter Mundel, and Andrey S. Shaw

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Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis, Sonja G. Hunter, Guanglei Zhuang, Dana Brantley-Sieders, Wojciech Swat, Christopher W. Cowan, and Jin Chen

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The molecular portraits of breast tumors are conserved across microarray platforms, Zhiyuan Hu, Cheng Fan, Daniel S. Oh, J S. Marron, Xiaping He, Bahjat F. Qaqish, Chad Livasy, Lisa A. Carey, Evangeline Reynolds, Lynn Dressler, Andrew Nobel, Joel Parker, Matthew G. Ewend, Lynda R. Sawyer, Junyuan Wu, Yudong Liu, Rita Nanda, Maria Tretiakova, Alejandra Ruiz Orrico, Donna Dreher, Juan P. Palazzo, Laurent Perreard, Edward Nelson, Mary Mone, Heidi Hansen, Michael Mullins, John F. Quackenbush, Matthew J. Ellis, Olufunmilayo I. Olopade, Philip S. Bernard, and Charles M. Perou

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ShiA abrogates the innate T-cell response to Shigella flexneri infection, Molly A. Ingersoll and Arturo Zychlinsky

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Pigment pattern in jaguar/obelix zebrafish is caused by a Kir7.1 mutation: Implications for the regulation of melanosome movement, Motoko Iwashita, Masakatsu Watanabe, Masaru Ishii, Tim Chen, Stephen L. Johnson, Yoshihisa Kurachi, Norihiro Okada, and Shigeru Kondo

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Proteinuria precedes podocyte abnormalities in Lamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier, George Jarad, Jeanette Cunningham, Andrey S. Shaw, and Jeffrey H. Miner

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Human sensory-evoked responses differ coincident with either "fusion-memory" or "flash-memory", as shown by stimulus repetition-rate effects, Don L. Jewett, Toryalai Hart, Linda J. Larson-Prior, Bill Baird, Marram Olson, Michael Trumpis, Katherine Makayed, and Payam Bavafa

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A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients, Peter R. Joyce, Patrick C. McHugh, Janice M. McKenzie, Patrick F. Sullivan, Roger T. Mulder, Suzanne E. Luty, Janet D. Carter, Christopher M. Frampton, and C. R. Cloninger

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Maturation of intracellular Escherichia coli communities requires SurA, Sheryl S. Justice, Scott R. Lauer, Scott J. Hultgren, and David A. Hunstad

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Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification, Sharon L.R. Kardia, Lawrence F. Bielak, Leslie A. Lange, James M. Cheverud, Eric Boerwinkle, Stephen T. Turner, Patrick F. Sheedy II, and Patricia A. Peyser

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Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK), Farzana Karim, Hui-Juan Hu, Hita Adwanikar, David Kaplan, and Robert W. Gereau IV

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Immunization with persistent attenuated Δlpg2 Leishmania major parasites requires adjuvant to provide protective immunity in C57BL/6 mice, Chahnaz Kebaier, Jude E. Uzonna, Stephen M. Beverley, and Phillip Scott

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A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors, Peter A. Keyel, Sanjay K. Mishra, Robyn Roth, John E. Heuser, Simon C. Watkins, and Linton M. Traub

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Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii, Asis Khan, L. David Sibley, and et al

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Dual infection with Mycobacterium tuberculosis and Pneumocystis jiroveci lymphadenitis in a patient with HIV infection: case report and review of the literature, Thana Khawcharoenporn, Anucha Apisarnthanarak, Dussadee Sakonlaya, Linda M. Mundy, and Thomas C. Bailey

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Proteasome activator PA200 is required for normal spermatogenesis, Bernard Khor, Andrea L. Bredemeyer, Ching-Yu Huang, Isaiah R. Turnbull, Ryan Evans, Leonard B. Maggi Jr., J. Michael White, Laura M. Walker, Kay Carnes, Rex A. Hess, and Barry P. Sleckman

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Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway, Dong-Jo Kim, Jun-Ho Chung, Eun-Kyeong Ryu, Jung-Hyo Rhim, Yoon-Sic Ryu, So-Hyun Park, Kyung Tae Kim, Heun-Soo Kang, Hong-Keun Chung, and Sang Chul Park

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Glucocorticoids suppress bone formation via the osteoclast, Hyun-Ju Kim, Haibo Zhao, Hideki Kitaura, Sandip Bhattacharyya, Judson A. Brewer, Louis J. Muglia, Patrick Ross, and Steven L. Teitelbaum

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Integration of transcriptional and posttranslational regulation in a glucose signal transduction pathway in Saccharomyces cerevisiae, Jeong-Ho Kim, Valerie Brachet, Hisao Moriya, and Mark Johnston

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Actin-based motility during endocytosis in budding yeast, Kyoungtae Kim, Brian J. Galletta, Kevin O. Schmidt, Fanny S. Chang, Kendall J. Blumer, and John A. Cooper

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Maternal alcohol use disorder and offspring ADHD: Disentangling genetic and environmental effects using a children-of-twins design, Valerie S. Knopik, Andrew C. Heath, Theodore Jacob, Wendy S. Slutske, Kathleen K. Bucholz, Pamela A F Madden, Mary Waldron, and Nicholas G. Martin

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The intensive care unit as a research laboratory: Developing strategies to prevent antimicrobial resistance, Marin H. Kollef

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The molecular scaffold kinase suppressor of Ras 1 is a modifier of Ras(V12)-induced and replicative senescence, Robert L. Kortum, Heidi J. Johnson, Diane L. Costanzo, Deanna J. Volle, Gina L. Razidlo, Angela M. Fusello, Andrey S. Shaw, and Robert E. Lewis

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The polyamine binding site in inward rectifier K+ channels, Harley T. Kurata, Laurence J. Marton, and Colin G. Nichols

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Comparison of the host responses to wild-type and cpsB mutant Klebsiella pneumoniae infections, Matthew S. Lawlor, Scott A. Handley, and Virginia L. Miller

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RNA in situ hybridization of dissected gonads, Min-Ho Lee and Tim Schedl

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RNA-binding proteins, Min'Ho Lee and Tim Schedl

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Quantitative effect of luxS gene inactivation on the fitness of Helicobacter pylori, Won-Kon Lee, Keiji Ogura, John T. Loh, Timothy L. Cover, and Douglas E. Berg

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Effect of lung surfactant collectins on bronchoalveolar macrophage interaction with Blastomyces dermatitidis: Inhibition of tumor necrosis factor alpha production by surfactant protein D, Madhavi Lekkala, Ann Marie LeVine, Michael J. Linke, Erika C. Crouch, Bruce Linders, Elmer Brummer, and David A. Stevens

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Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit, Van Leung-Pineda, Christine E. Ryan, and Helen Piwnica-Worms

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Unexpected diversity and complexity of the Guerrero Negro hypersaline microbial mat, Ruth Ley, J. Kirk Harris, Joshua Wilcox, John R. Spear, Scott R. Miller, Brad M. Bebout, Julia A. Maresca, Donald A. Bryant, Mitchell L. Sogin, and Norman R. Pace

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Blinded comparison of repetitive-sequence PCR and multilocus sequence typing for genotyping methicillin-resistant Staphylococcus aureus isolates from a children's hospital in St. Louis, Missouri, Robert S. Liao, Gregory A. Storch, Richard S. Buller, Rachel C. Orscheln, Elaine R. Mardis, Jon R. Armstrong, and W. Michael Dunne Jr.

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Enhanced analgesia with opioid antagonist administration, Jane E. Loitman

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A unique role for Stat5 in recovery from acute anemia, Gregory D. Longmore

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Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a model for in vivo gene expression, Jennifer A. Loughman and Michael Caparon

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Effect of conventional and organic production practices on the prevalence and antimicrobial resistance of Campylobacter spp. in poultry, Taradon Luangtongkum, Teresa Y. Morishita, Aaron J. Ison, Shouxiong Huang, Patrick F. McDermott, and Qijing Zhang

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Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy, Joan Luby, Christine Mrakotsky, Melissa Meade Stalets, Andy Belden, Amy Heffelfinger, Meghan Williams, and Edward Spitznagel

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A gene expression signature predicts survival of patients with stage I non-small cell lung cancer, Yan Lu, William Lemon, Peng-Yuan Liu, Yigun Yi, Carl Morrison, Ping Yang, Zhifu Sun, Janos Szoke, William L. Gerald, Mark Watson, Ramaswamy Govindan, and Ming You

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Cold shock domain family members YB-1 and MSY4 share essential functions during murine embryogenesis, Zhi Hong Lu, Jason T. Books, and Timothy J. Ley

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Subtypes of illicit drug users: A latent class analysis of data from an Australian twin sample, Michael T. Lynskey, Arpana Agrawal, Kathleen K. Bucholz, Elliot C. Nelson, Pamela A.F. Madden, Alexandre A. Todorov, Julia D. Grant, Nicholas G. Martin, and Andrew C. Heath

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An improved map of conserved regulatory sites for Saccharomyces cerevisiae, Kenzie D. MacIsaac, Ting Wang, D Benjamin Gordon, David K. Gifford, Gary D. Stormo, and Ernest Fraenkel

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Rab22a regulates the sorting of transferrin to recycling endosomes, Javier G. Magadan, M. Alejandro Barbieri, Rosana Mesa, Philip D. Stahl, and Luis S. Mayorga

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Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans, Timothy R. Mahoney, Qiang Liu, Takashi Itoh, Shuo Luo, Gayla Hadwiger, Rose Vincent, Zhao-Wen Wang, Mitsunori Fukuda, and Michael L. Nonet

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Autoreactive marginal zone B cells are spontaneously activated but lymph node B cells require T cell help, Laura Mandik-Nayak, Jennifer Racz, Barry P. Sleckman, and Paul M. Allen

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PLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2, Dailing Mao, Holly Epple, Brian Uthgenannt, Deborah V. Novack, and Roberta Faccio

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Lack of insurance coverage and urgent care use for asthma: A retrospective cohort study, Barry P. Markovitz and Elena M. Andresen

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Reliability of a visual analog version of the QuickDASH, Leonard N. Matheson, J. Mark Melhorn, Tom G. Mayer, Brian R. Theodore, and Robert J. Gatchel

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Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis, Zhefu Ma, Shannon L. Gibson, Maura A. Byrne, Junran Zhang, Morris F. White, and Leslie M. Shaw

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Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses, Kelly B. McClellan, Shivaprakash Gangappa, Samuel H. Speck, and Herbert W. Virgin IV

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Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice, Precious J. McLaughlin, Qiuyun Chen, Masahito Horiguchi, Barry C. Starcher, J. Brett Stanton, Thomas J. Broekelmann, Alan D. Marmorstein, Brian McKay, Robert Mecham, Tomoyuki Nakamura, and Lihua Y. Marmorstein

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Protective immune responses against West Nile virus are primed by distinct complement activation pathways, Erin Mehlhop and Michael S. Diamond

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Physical map-assisted whole-genome shotgun sequence assemblies, David Messina, Shiaw-Pyng Yang, Wesley C. Warren, John W. Wallis, LaDeana W. Hillier, Asif T. Chinwalla, and Richard K. Wilson

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Characterization of a novel porin involved in systemic Yersinia enterocolitica infection, Shirly Mildiner-Earley and Virginia L. Miller

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Development of the minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE), Jason C. Mills and et al

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Biology and genome of Trichinella spiralis, Makedonka Mitreva and Douglas P. Jasmer

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Codon usage patterns in Nematoda: Analysis based on over 25 million codons in thirty-two species, Makedonka Mitreva, Michael C. Wendl, John Martin, Todd Wylie, Yong Yin, Allan Larson, John Parkinson, Robert H. Waterston, and James P. McCarter

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Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD, Parastoo Momeni, Jennifer Schymick, Shushant Jain, Mark R. Cookson, Nigel J. Cairns, Elisa Greggio, Matthew J. Greenway, Stephen Berger, Stuart Pickering-Brown, Adriano Chiò, Hon Chung Fung, David M. Holtzman, Edward D. Huey, Eric M. Wassermann, Jennifer Adamson, Michael L. Hutton, Ekaterina Rogaeva, Peter St George-Hyslop, Jeffrey D. Rothstein, Orla Hardiman, Jordan Grafman, Andrew Singleton, John Hardy, and Bryan J. Traynor

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Childhood sexual abuse and risks for licit and illicit drug-related outcomes: A twin study, Elliot C. Nelson, Andrew C. Heath, Michael T. Lynskey, Kathleen K. Bucholz, Pamela A F Madden, Dixie J. Statham, and Nicholas G. Martin

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A response to high-dose estrogen for tamoxifen, aromatase inhibitor and trastuzumab refractory HER2+ and ER+ advanced breast cancer, B. Nervi, A. Denes, and M. J. Ellis

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Genotyping of toxoplasma gondii by multiplex PCR and peptide-based serological testing of samples from infants in Poland diagnosed with congenital toxoplasmosis, Dorota Nowakowska, Iris Colon, Jack S. Remington, Michael Grigg, Elzbieta Golab, J. Wilczynski, and L. D. Sibley

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Evaluating the efficiency of using second-trimester nasal bone hypoplasia as a single or a combined marker for fetal aneuploidy, Anthony O. Odibo, Harish M. Sehdev, Laura Sproat, Claudia Parra, Linda Odibo, Linda Dunn, and George A. Macones

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Vignettes: diverse library staff offering diverse bioinformatics services, David L. Osterbur, Kristine Alpi, Catarine Canevari, Pamela M. Corley, Medha Devare, Nicola Gaedeke, Donna K. Jacobs, Peter Kirlew, Janet A. Ohles, K.T.L. Vaughan, Lili Wang, Yongchun Wu, and Renata C. Greer

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Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair, Raj K. Pandita, Girdhar G. Sharma, Andrei Laszlo, Kevin M. Hopkins, Scott Davey, Mikhail Chakhparonian, Arun Gupta, Raymund J. Wellinger, Junran Zhang, Simon N. Powell, Joseph L. Roti Roti, Howard B. Lieberman, and Tej K. Pandita

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Role of mammalian Rad9 in genomic stability and ionizing radiation response, Tej K. Pandita

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NF-κB-inducing kinase regulates selected gene expression in the Nod2 signaling pathway, Qilin Pan, Vladimir Kravchenko, Alex Katz, Shuang Huang, Masayuki Ii, John C. Mathison, Koichi Kobayashi, Richard A. Flavell, Robert D. Schreiber, David Goeddel, and Richard J. Ulevitch

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Antimalarial effects of human immunodeficiency virus type 1 protease inhibitors differ from those of the aspartic protease inhibitor pepstatin, Sunil Parikh, Jun Liu, Puran Sijwali, Jiri Gut, Daniel E. Goldberg, and Philip J. Rosenthal

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Anti-apoptotic effects of caspase inhibitors on rat intervertebral disc cells, Jon-Beom Park, In-Chul Park, Sung-Jin Park, Hyeon-Ok Jin, Jin-Kyung Lee, and K. Daniel Riew

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Genetic analyses of DSM-IV nicotine withdrawal in adult twins, Michele L. Pergadia, Andrew C. Heath, Nicholas G. Martin, and Pamela A F Madden

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Prospective measurement of function and pain in patients with non-neoplastic compression fractures treated with vertebroplasty, Heidi Prather, Linda Van Dillen, John P. Metzler, K. Daniel Riew, and Louis A. Gilula

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Ciprofloxacin-resistant gram-negative bacilli in the fecal microflora of children, Xuan Qin, Yasmin Razia, James R. Johnson, Jennifer R. Stapp, Daniel R. Boster, Treva Tsosie, Donna L. Smith, Christopher R. Braden, Kathryn Gay, Frederick J. Angulo, and Phillip I. Tarr

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A real-time PCR-based assay for detection of Wuchereria bancrofti DNA in blood and mosquitoes, Ramakrishna U. Rao, Laura J. Atkinson, Reda M.R. Ramzy, Hanan Helmy, Hoda A. Farid, Moses J. Bockarie, Melinda Susapu, Sandra J. Laney, Steven A. Williams, and Gary J. Weil

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Cytokine profiles of filarial granulomas in jirds infected with Brugia pahangi, Ramakrishna U. Rao and Thomas R. Klei

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Detection of Brugia parasite DNA in human blood by real-time PCR, Ramakrishna U. Rao, Gary J. Weil, Kerstin Fischer, Taniawati Supali, and Peter Fischer

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Expression of putative virulence factors of Escherichia coli O157:H7 differs in bovine and human infections, Rebecca A. Rashid, Tami A. Tabata, Melissa J. Oatley, Thomas E. Besser, Phillip I. Tarr, and Steve L. Moseley

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Duloxetine versus routine care in the long-term management of diabetic peripheral neuropathic pain, Joel Raskin, Timothy R. Smith, Kar Wong, Yili Lu Pritchett, Deborah N. D'Souza, Smriti Iyengar, and J. F. Wernicke

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The generation and function of soluble apoE receptors in the CNS, G William Rebeck, Mary Jo LaDu, Steven Estus, Guojun Bu, and Edwin J. Weeber

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Nerve root blocks in the treatment of lumbar radicular pain: A minimum five-year follow-up, K. Daniel Riew, Jong-Beom Park, Yong-Sun Cho, Louis Gilula, Alpesh Patel, Lawrence G. Lenke, and Keith H. Bridwell

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Nothing but skin and bone, F. Patrick Ross and Angela M. Christiano

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Unusual kinetic and structural properties control rapid assembly and turnover of actin in the parasite Toxoplasma gondii, Nivedita Sahoo, Wandy Beatty, John Heuser, David Sept, and L. David Sibley

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A Tail of multiple calcium-sensing domains, Lawrence Salkoff

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CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion, Miguel A. Sanjuan, Navin Rao, Kuei-Tai A. Lai, Yin Gu, Siquan Sun, Anja Fuchs, Wai-Ping Fung-Leung, Marco Colonna, and Lars Karlsson

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Insulin resistance and atherosclerosis, Clay F. Semenkovich

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Geminin's double life: Chromatin connections that regulate transcription at the transition from proliferation to differentiation, Seongjin Seo and Kristen L. Kroll

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Surveillance for vancomycin-resistant enterococci: Type, rates, costs, and implications, Brooke N. Shadel, Laura A. Puzniak, Kathleen N. Gillespie, Steven J. Lawrence, Marin Kollef, and Linda M. Mundy

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Blocking monoclonal antibodies specific for mouse IFN-α/β receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection, Kathleen C F Sheehan, Koon Siew Lai, Gavin P. Dunn, Allen T. Bruce, Mark S. Diamond, Jennifer D. Heutel, Corazon Dungo-Arthur, Javier A. Carrero, J. Michael White, Paul J. Herzog, and Robert D. Schreiber

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A prospective study of differences in duodenum compared to remaining small bowel motion between radiation treatments: Implications for radiation dose escalation in carcinoma of the pancreas, Anurag K. Singh, Ryan M. Tierney, Daniel A. Low, Parag J. Parikh, Robert J. Myerson, Joseph O. Deasy, Catherine S. Wu, Gisele C. Pereira, Sasha H. Wahab, Sasa Mutic MS, Perry W. Grigsby, and Andrew J. Hope

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Research with Arctic peoples: Unique research opportunities in heart, lung, blood and sleep disorders. Working group summary and recommendations, Sally Smith, Peter Bjerregaard, Hing Man Chan, André Corriveau, Sven Ebbesson, Ruth Etzel, Richard Fabsitz, Hakon Hakonarson, Carl Hild, Elizabeth Nobmann, Jeff Reading, Larisa Tereshchenko, T. Kue Young, and Barbara Howard

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Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host, Justin L. Sonnenburg, Christina T. Chen, and Jeffery I. Gordon

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COG-7-deficient human fibroblasts exhibit altered recycling of Golgi proteins, Richard Steet and Stuart Kornfeld

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The role of myristoylation in the membrane association of the Lassa virus matrix protein Z, Thomas Strecker, Anna Maisa, Stephane Daffis, Robert Eichler, Oliver Lenz, and Wolfgang Garten

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The Haemophilus influenzae Type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence, Soila Sukupolvi-Petty, Susan Grass, and Joseph W. St. Geme III