The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2006
Choosing the best heuristic for seeded alignment of DNA sequences, Yanni Sun and Jeremy Buhler
PKR-dependent autophagic degradation of herpes simplex virus type 1, Zsolt Talloczy, Herbert W. Virgin IV, and Beth Levine
Cortactin has an essential and specific role in osteoclast actin assembly, Shandiz Tehrani, Roberta Faccio, Indra Chandrasekar, F. Patrick Ross, and John A. Cooper
Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion, Joshua M. Thurman, Danica Ljubanovic, Pamela A. Royer, Damian M. Kraus, Hector Molina, Nicholas P. Barry, Gregory Proctor, Moshe Levi, and V. Michael Holers
The alchemy of tendon repair: A primer for the (S)mad scientist, Dwight A. Towler and Richard H. Gelberman
Endocytosis of cadherin from intracellular junctions is the driving force for cadherin adhesive dimer disassembly, Regina B. Troyanovsky, Eugene P. Sokolov, and Sergey M. Troyanovsky
Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals, Jeffrey W. Tyner, Edy Y. Kim, Kyotaro Ide, Mark R. Pelletier, William T. Roswit, Jeffrey D. Morton, John T. Battaile, Anand C. Patel, G. Alexander Patterson, Mario Castro, Melanie S. Spoor, Yingjian You, Steven L. Brody, and Michael Holtzman
Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes, Teun WJM van Herpen, Svetlana V. Goryunova, Johanna van der Schoot, Makedonka Mitreva, Elma Salentijn, Oscar Vorst, Martijn F. Schenk, Peter A. van Veelen, Frits Koning, Loek JM van Soest, Ben Vosman, Dirk Bosch, Rob J. Hamer, Luud JWJ Gilissen, and Marinus JM Smulders
Validation of string test for diagnosis of Helicobacter pylon infections, Billie Velapatino, Jacqueline Balqui, Robert H. Gilman, Alejandro Bussalleu, Willi Quino, S. Alison Finger, Livia Santivanez, Phabiola Herrera, Alejandro Piscoya, Jose Valdiva, Jaime Cok, and Douglas E. Berg
Identification of non-dot/icm suppressors of the Legionella pneumophila △dotL lethality phenotype, Carr D. Vincent, Benjamin A. Buscher, Jonathan R. Friedman, Lee Anne Williams, Patrick Bardill, and Joseph P. Vogel
Genetic influences on free and cued recall in long-term memory tasks, Heather E. Volk, Kathleen B. McDermott, Henry L. Roediger III, and Richard D. Todd
Las noticias de Madrid (News from Madrid), Suzanne Elizabeth Wahrle
A steganalysis-based approach to comprehensive identification and characterization of functional regulatory elements, Guandong Wang and Weixiong Zhang
Epimorphin-/- mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis, Yuan Wang, Lihua Wang, Hristo Iordanov, Elzbieta A. Sweitlicki, Qun Zheng, Shujun Jiang, Yuzhu Tang, Marc S. Levin, and Deborah C. Rubin
A multicenter intervention to prevent catheter-associate bloodstream infections, David K. Warren, Sara E. Cosgrove, Daniel J. Diekema, Gianna Zuccotti, Michael W. Climo, Maureen K. Bolon, Jerome I. Tokars, Gary A. Noskin, Edward S. Wong, Kent A. Sepkowitz, Loreen A. Herwaldt, Trish M. Perl, Steven L. Solomon, and Victoria J. Fraser
Epidemiology of methicillin-resistant Staphylococcus aureus colonization in a surgical intensive care unit, David K. Warren, Rebecca M. Guth, Craig M. Coopersmith, Liana R. Merz, Jeanne E. Zack, and Victoria J. Fraser
Preventing catheter-associated bloodstream infections: A survey of policies for insertion and care of central venous catheters from hospitals in the prevention epicenter program, David K. Warren, Deborah S. Yokoe, Michael W. Climo, Loreen A. Herwaldt, Gary A. Noskin, Gianna Zuccotti, Jermone I. Tokars, Trish M. Perl, and Victoria J. Fraser
A general coverage theory for shotgun DNA sequencing, Michael C. Wendl
The demographic and morphological features of rotator cuff disease: A comparison of asymptomatic and symptomatic shoulders, Ken Yamaguchi, Konstantinos Ditsios, William D. Middleton, Charles F. Hildebolt, Leesa M. Galatz, and Sharlene A. Teefey
Harpin mediates cell aggregation in Erwinia chrysanthemi 3937, Mee-Ngan Yap, Clemencia M. Rojas, Ching-Hong Yang, and Amy O. Charkowski
A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis, Aki Yoneda and Tamara L. Doering
Nucleophosmin is essential for ribosomal protein L5 nuclear export, Yue Yu, Leonard B. Maggi Jr., Suzanne N. Brady, Anthony J. Apicelli, Mu-Shui Dai, Hua Lu, and Jason D. Weber
Slo3 K+ channels: Voltage and pH dependence of macroscopic currents, Xue Zhang, Xuhui Zeng, and Christopher J. Lingle
pH-regulated Slo3 K+ channels: Properties of unitary currents, Xue Zhang, Xuhui Zeng, Xiao-Ming Xia, and Christopher J. Lingle
The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins, Xuejun Zhong, Parie Garg, Stephanie A. Nick McElhinny, Carrie M. Stith, Grace E. Kissling, Peter M.J. Burgers, and Thomas A. Kunkel
Submissions from 2005
CD36 may determine our desire for dietary fats, Nada A. Abumrad
Low ambient O2 enhances ureteric bud branching in vitro, Tetsu Akimoto, Marc R. Hammerman, and Eiji Kusano
Comparison of holding strength of suture anchors for hepatic and renal parenchyma, Caroline D. Ames, Juan M. Perrone, Alison J. Frisella, Kevin Morrissey, and Jaime Landman
Preclinical and clinical performance of the Efoora test, a rapid test for detection of human immunodeficiency virus-specific antibodies, Max Q. Arens, Linda M. Mundy, and et al
NF-κB-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis, Kunihiko Aya, Muhammad Alhawagri, Amanda Hagen-Stapleton, Hideki Kitaura, Osami Kanagawa, and Deborah Veis Novack
Genetic Analysis Workshop 14: Microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans, Joan E. Bailey-Wilson, Laura Almasy, Mariza de Andrade, Julia Bailey, Heike Bickeböller, Heather J. Cordell, E Warwick Daw, Lynn Goldin, Ellen L. Goode, Courtney Gray-McGuire, Wayne Hening, Gail Jarvik, Brion S. Maher, Nancy Mendell, Andrew D. Paterson, John Rice, Glen Satten, Brian Suarez, Veronica Vieland, Marsha Wilcox, Heping Zhang, Andreas Ziegler, and Jean W. MacCluer
FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner, Shuting Bai, Hideki Kitaura, Haibo Zhao, Ju Chen, Judith M. Muller, Roland Schule, Bryant Darnay, Deborah V. Novack, Patrick Ross, and Steven L. Teitelbaum
Eukaryotic UDP-galactopyranose mutase (GLF Gene) in microbial and metazoal pathogens, Stephen M. Beverley, Katherine L. Owens, Melissa Showalter, Cara L. Griffith, Tamara L. Doering, Victoria C. Jones, and Michael R. McNeil
Phenotypic and molecular analysis of tellurite resistance among enterohemorrhagic Escherichia coli O157:H7 and sorbitol-fermenting O157:NM clinical isolates, Martina Bielaszewska, Phillip I. Tarr, Helge Karch, Wenlan Zhang, and Werner Mathys
Molecular profiling and phenotype analysis of Escherichia coli O26:H11 and O26:NM: Secular and geographic consistency of enterohemorrhagic and enteropathogenic isolates, Martina Bielaszewska, Wenlan Zhang, Phillip I. Tarr, Anne-Katharina Sonntag, and Helge Karch
Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality, Valerie Blanc, Jeffrey O. Henderson, Elizabeth P. Newberry, Susan Kennedy, Jianyang Luo, and Nicholas O. Davidson
The ethics and politics of stem cell research, James C. Bobrow
An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism, Michael R. Bowl, Andrew Nesbit, Brian Harding, Elaine Levy, Andrew Jefferson, Emanuela Volpi, Karine Rizzoti, Robin Lovell-Badge, David Schlessinger, Michael P. Whyte, and Rajesh V. Thakker
Objectives of undergraduate medical education in musculoskeletal surgery and medicine, Martin I. Boyer
Anti-Aβ antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice, Robert P. Brendza, Brain J. Bacskai, John R. Cirrito, Kelly A. Simmons, Jesse M. Skoch, William E. Klunk, Chester A. Mathis, Kelly R. Bales, Steven M. Paul, Bradley T. Hyman, and David M. Holtzman
What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang
The DotL protein, a member of the TraG-coupling protein family, is essential for viability of Legionella pneumophila strain Lp02, Benjamin A. Buscher, Gloria M. Conover, Jennifer L. Miller, Sinae A. Vogel, Stacey N. Meyers, Ralph R. Isberg, and Joseph P. Vogel
Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex, Goran O. Bylund and Peter M. J. Burgers
The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein, David A. Canton, Mary Ellen K. Olsten, Kyoungtae Kim, Amanda Doherty-Kirby, Gilles Lajoie, John A. Cooper, and David W. Litchfield
Antioxidant supplementation for the prevention of kwashiorkor in Malawian children: Randomised, double blind, placebo controlled trial, Heather Ciliberto, Michael Ciliberto, Andree Briend, Per Ashorn, Dennis Bier, and Mark Manary
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model, John R. Cirrito, Rashid Deane, Anne M. Fagan, Michael L. Spinner, Maia Parsadanian, Mary Beth Finn, Hong Jiang, Julie L. Prior, Abhay Sagare, Kelly R. Bales, Steven M. Paul, Berislav V. Zlokovic, David Piwinca-Worms, and David M. Holtzman
Periacetabular osteotomy for the treatment of severe acetabular dysplasia, John C. Clohisy, Susan E. Barrett, J. Eric Gordon, Eliana D. Delgado, and Perry L. Schoenecker
Architecture and adhesive activity of the Haemophilus influenzae Hsf adhesin, Shane E. Cotter, Hye-Jeong Yeo, Twyla Juehne, and Joseph W. St. Geme III
Identification of functional transcription factor binding sites using closely related Saccharomyces species, Scott W. Doniger, Juyoung Huh, and Justin C. Fay
CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood, Victor A. Drover, Mohammad Ajmal, Fatiha Nassir, Nicholas O. Davidson, Andromeda M. Nauli, Daisy Sahoo, Patrick Tso, and Nada A. Abumrad
Use of several inducer and substrate antibiotic combinations in a disk approximation assay format to screen for AmpC induction in patient isolates of Pseudomonas aeruginosa, Enterobacter spp., Citrobacter spp., and Serratia spp., W. Michael Dunne Jr. and Daniel J. Hardin
Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures, Gerald Dunn, Anthony L. Hinrichs, Sarah Bertelsen, Carol H. Jin, John SK Kauwe, Brian K. Suarez, and Laura J. Bierut
A model of the statistical power of comparative genome sequence analysis, Sean R. Eddy
‘‘Antedisciplinary’’ science, Sean R. Eddy
Gene finding in the chicken genome, Eduardo Eyras, Alexandre Reymond, Robert Castelo, Jacqueline M. Bye, Francisco Camara, Paul Flicek, Elizabeth J. Huckle, Genis Parra, David D. Shteynberg, Carine Wyss, Jane Rogers, Stylianos E. Antonarakis, Ewan Birney, Roderic Guigo, and Michael R. Brent
Effects of combined diethylcarbamazine and albendazole treatment of bancroftian filariasis on parasite uptake and development in Culex pipiens L., Hoda A. Farid; Ragaa E. Hammad; Marah M. Hassan; Reda M.R, Ramzy; Maged El Setouhy; and Gary J. Weil
Evidence for domesticated and wild populations of saccharomyces cerevisiae, Justin C. Fay and Joseph A. Benavides
The LIM protein Ajuba influences interleukin-1-induced NF-κB activation by affecting the assembly and activity of the protein kinase Cζ/p62/TRAF6 signaling complex, Yungfeng Feng and Gregory D. Longmore
Dominant negative effects of the AML1/ETO fusion oncoprotein, Timothy S. Fenske, Gina Pengue, and Timothy A. Graubert
Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases, Angela M. Ferguson, Lynn S. White, Peter J. Donovan, and Helen Piwnica-Worms
Patterns and predictors of inpatient falls and fall-related injuries in a large academic hospital, Irene D. Fischer, Melissa J. Krauss, William Claiborne Dunagan, Stanley Birge, Eileen Hitcho, Shirley Johnson, Eileen Constantinou, and Victoria J. Fraser
Pseudomonas aeruginosa acquires biofilm-like properties within airway epithelial cells, Raquel Garcia-Medina, W. Michael Dunne, Pradeep K. Singh, and Steven L. Brody
How the cell deals with DNA nicks, Parie Garg and Peter M.J. Burgers
Computational technique for improvement of the position-weight matrices for the DNA/protein binding sites, Naum I. Gershenzon, Gary D. Stormo, and Illya P. Ioshikhes
Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics, Jason Gertz, Linda Riles, Peter Turnbaugh, Su-Wen Ho, and Barak A. Cohen
Analysis of memory T lymphocyte activity following stimulation with overlapping HLA-A*2402, A*0101 and Cw*0402 restricted CMV pp65 peptides, Monica Ghei, David F. Stroncek, and Maurizio Provenzano
Reporting quality of randomized trials in the diet and exercise literature for weight loss, Cheryl A. Gibson, Erik P. Kirk, James D. LeCheminant, Bruce W. Bailey Jr, Guoyuan Huang, and Joseph E. Donnelly
The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression, Nathan A. Gillespie, John B. Whitfield, Ben Williams, Andrew C. Heath, and Nicholas G. Martin
Upper-extremity phocomelia reexamined: A longitudinal dysplasia, Charles A. Goldfarb, Paul R. Manske, Riccardo Busa, Janith Mills, Peter Carter, and Marybeth Ezaki
Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites, Jennifer L. Gordon and L David Sibley
Comprehensive treatment of late-onset tibia vara, J. Eric Gordon, Fred P. Heidenreich, Chris J. Carpenter, Jill Kelly-Hahn, and Perry L. Schoenecker
Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: Evidence from a twin design, Julia D. Grant, Jeffrey F. Scherrer, Michael T. Lynskey, Michael J. Lyons, Seth A. Eisen, Ming T. Tsuang, William R. true, and Kathleen K. Bucholz
Rfam: Annotating non-coding RNAs in complete genomes, Sam Griffiths-Jones, Simon Moxon, Mhairi Marshall, Ajay Khanna, Sean R. Eddy, and Alex Bateman
The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells, Thomas E. Grys, Matthew B. Siegel, Wyndham W. Lathem, and Rodney A. Welch
Involvement of human MOF in ATM function, Arun Gupta, Girdhar G. Sharma, Charles S. H. Young, Manjula Agarwal, Edwin R. Smith, Tanya T. Paull, John C. Lucchesi, Kum Kum Khanna, Thomas Ludwig, and Tej K. Pandita
Paternal alcoholism and offspring conduct disorder: Evidence for the 'common genes' hypothesis, Jon R. Haber, Theodore Jacob, and Andrew C. Heath
Yersinia enterocolitica invasin-dependent and invasin-independent mechanisms of systemic dissemination, Scott A. Handley, Rodney D. Newberry, and Virginia L. Miller
Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant, J. Hiemenz, P. Cagnoni, D. Simpson, S. Devine, N. Chao, J. Keirns, W. Lau, D. Facklam, and D. Buell
Genomics in C. elegans: So many genes, such a little worm, LaDeana W. Hillier, Alan Coulson, John I. Murray, Zhirong Bao, John E. Sulston, and Robert H. Waterston
Multipoint identity-by-descent computations for single-point polymorphism and microsatellite maps, Anthony L. Hinrichs, Sarah Bertelsen, Laura J. Bierut, Gerald Dunn, Carol H. Jin, John S. Kauwe, and Brian K. Suarez
Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death, William A. Holtz, Jay M. Turetzky, and Karen L. O'Malley
Ultrasonic songs of male mice, Timothy E. Holy and Zhongsheng Guo
Punctuated duplication seeding events during the evolution of human chromosome 2p11, Julie E. Horvath, Cassandra L. Gulden, Rhea U. Vallente, Marla Y. Eichler, Mario Ventura, John D. McPherson, Tina A. Graves, Richard K. Wilson, Stuart Schwartz, Mariano Rocchi, and Evan E. Eichler
Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli, David A. Hunstad, Sheryl S. Justice, Chia S. Hung, Scott R. Lauer, and Scott J. Hultgren
Mitochondrial energy metabolism in heart failure: A question of balance, Janice M. Huss and Daniel P. Kelly
The type Iα inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane, Ivan Ivetac, Adam D. Munday, Marina V. Kisseleva, Xiang-Ming Zhang, Susan Luff, Tony Tiganis, James C. Whisstock, Tony Rowe, Phillip W. Majerus, and Christina A. Mitchell
An improved internal mammary irradiation technique in radiation treatment of locally advanced breast cancers, Jian-Yue Jin, Eric E. Klein, Feng-Ming Kong, and Zuofeng Li
The multiple biological roles of the 3’→5’ exonuclease of Saccharomyces cerevisiae DNA polymerase δ require switching between the polymerase and exonuclease domains, Yong Hawn Jin, Parie Garg, Carrie M. W. Stith, Hanan Al-Refai, Joan F. Sterling, Laura J. W. Murray, Thomas A. Kunkel, Michael A. Resnick, Peter M. Burgers, and Dmitry A. Gordenin
Use of in vivo-induced antigen technology for identification of Escherichia coli O157:H7 proteins expressed during human infection, Manohar John, Indira T. Kudva, Robert W. Griffin, Allen W. Dodson, Bethany McManus, Bryan Krastins, David Sarracino, Ann Progulske-Fox, Jeffrey D. Hillman, Martin Handfield, Phillip I. Tarr, and Stephen B. Calderwood
The IrgA homologue adhesin Iha is an Escherichia coli virulence factor in murine urinary tract infection, James R. Johnson, Srdjan Jelacic, Laura M. Schoening, Connie Clabots, Nurmohammad Shaikh, Harry L.T. Mobley, and Phillip I. Tarr
Arthrodesis techniques in the management of stage-II and III acquired adult flatfoot deformity, Jeffrey E. Johnson and James R. Yu
Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA Is required for pilus biogenesis in Escherichia coli, Sheryl S. Justice, David A. Hunstad, Jill Reiss Harper, Amy R. Duguay, Jerome S. Pinkner, James Bann, Carl Frieden, Thomas J. Silhavy, and Scott J. Hultgren
An antagonist peptide mediates positive selection and CD4 lineage commitment of MHC class II–restricted T cells in the absence of CD4, Henry Kao and Paul M. Allen
Comparing low coverage random shotgun sequence data from Brassica oleracea and Oryza sativa genome sequence for their ability to add to the annotation of Arabidopsis thaliana, Manpreet S. Katari, Vivekanand Balija, Richard K. Wilson, Robert A. Martienssen, and W. Richard McCombie
Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice, Andrew L. Kau, Steven M. Martin, William Lyon, Ericka Hayes, Michael G. Caparon, and Scott J. Hultgren
The efficacy of short tandem repeat polymorphisms versus single-nucleotide polymorphisms for resolving population structure, John SK Kauwe, Sarah Bertelsen, Laura Jean Bierut, Gerald Dunn, Anthony L. Hinrichs, Carol H. Jin, and Brian K. Suarez
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii, Asis Khan, Sonya Taylor, Chunlei Su, Aaron J. Mackey, Jon Boyle, Robert Cole, Darius Glover, Keliang Tang, Ian T. Paulsen, Matt Berriman, John C. Boothroyd, Elmer R. Pfefferkorn, J. P. Dubey, James W. Ajioka, David S. Roos, John C. Wooton, and L. D. Sibley
Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains, A. Khan, C. Su, M. German, G. A. Storch, D. B. Clifford, and L. David Sibley
Eradication of methicillin-resistant Staphylococcus aureus from a neonatal intensive care unit by active surveillance and aggressive infection control measures, Jad Khoury, Marilyn Jones, Autumn Grim, Wm. Michael Dunne Jr., and Vicky Fraser