The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2010

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Sliding-clip renorrhaphy provides superior closing tension during robot-assisted partial nephrectomy, Brian M. Benway, Jose M. Cabello, Robert S. Figenshau, and Sam B. Bhayani

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Osseous metaplasia late in the course of nephrogenic systemic fibrosis, David R. Berk, Alicia Miller, Debra Scarlett, Franz J. Wippold II, Susan J. Bayliss, and Dongsi Lu

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Transgenic overexpression of active calcineurin in beta-cells results in decreased beta-cell mass and hyperglycemia, Ernesto Bernal-Mizrachi, Corentin Cras-Meneur, Bo Ra Ye, James D. Johnson, and M. Alan Permutt

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The epidemiology of hematogenous vertebral osteomyelitis: A cohort study in a tertiary care hospital, Kavita P. Bhavan, Jonas Marschall, Margaret A. Olsen, Victoria J. Fraser, Neill M. Wright, and David K. Warren

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Report from the 2009 AOA North American traveling fellowship, Ryan T. Bicknell, Gregory J. Della Rocca, Wellington K. Hsu, Amanda D. Marshall, and Robert H. Brophy

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Supporting Cells Eliminate Dying Sensory Hair Cells to Maintain Epithelial Integrity in the Avian Inner Ear, Jonathan E. Bird, Nicolas Daudet, Mark E. Warchol, and Jonathan E. Gale

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Quantification of indirect pathway inhibition by the adenosine A 2a antagonist SYN115 in Parkinson disease, Kevin J. Black, Jonathan M. Koller, Meghan C. Campbell, Debra A. Gusnard, and Stephen I. Bandak

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Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks, Emma Bolderson, Nozomi Tomimatsu, Derek J. Richard, Didier Boucher, Rakesh Kumar, Tej K. Pandita, Sandeep Burma, and Kum K. Khanna

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mmunohistological studies on neoplasms of female and male Onchocerca volvulus: Filarial origin and absence of Wolbachia from tumor cells, N. W. Brattig, A. Hoerauf, Peter U. Fischer, E. Liebau, C. Bandi, A. Debrah, M. Büttner, and W. Büttner

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang

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Classification of traumatic brain injury for targeted therapies, David Brody and et al

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Defective cAMP generation underlies the sensitivity of CNS neurons to neurofibromatosis-1 heterozygosity, Jacquelyn A. Brown, Scott M. Gianino, and David H. Gutmann

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Pre-steady-state kinetic analysis of truncated and full-length Saccharomyces cerevisiae DNA polymerase eta, Jessica A. Brown, Likui Zhang, Shanen M. Sherrer, John-Stephen Taylor, Peter M.J. Burgers, and Zucai Suo

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Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase, Sarah M. Brown, Rajendra Upadhya, James D. Shoemaker, and Jennifer K. Lodge

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Measuring the impact of public health policy, Ross C. Brownson, Rachel Seiler, and Amy A. Eyler

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Histopathology of nonalcoholic fatty liver disease, Elizabeth M. Brunt and Dina G. Tiniakos

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Images in clinical medicine. Meckel's diverticulum, Brian T. Bucher and Martin S. Keller

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Rhomboid 4 (ROM4) affects the processing of surface adhesins and facilitates host cell invasion by Toxoplasma gondii, Jeffrey S. Buguliskis, Fabien Brossier, Joel Shuman, and L. David Sibley

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Yeast exonuclease 5 is essential for mitochondrial genome maintenance, Peter M. Burgers, Carrie M. Stith, Bonita L. Yoder, and Justin L. Sparks

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Association of IL4R single-nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis, Paula I. Burgos, Zenoria L. Causey, Ashutosh Tamhane, James M. Kelley, Elizabeth E. Brown, Laura B. Hughes, Maria I. Danila, Amalia van Everdingen, Doyt L. Conn, Beth L. Jonas, Leigh F. Callahan, Edwin A. Smith, Richard D. Brasington Jr, Larry W. Moreland, Desiree M. van der Heijde, Graciela S. Alarcon, and S Louis Bridges Jr

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Novel screening agar for detection of vancomycin-nonsusceptible Staphylococcus aureus, Carey-Ann D. Burnham, Carol J. Weber, and W. Michael Dunne Jr.

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Integrated genomics of susceptibility to alkylator-induced leukemia in mice, Patrick Cahan and Timothy A. Graubert

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A crossover intervention trial evaluating the efficacy of a chlorhexidine-impregnated sponge in reducing catheter-related bloodstream infections among patients undergoing hemodialysis, Bernard C. Camins, Amy M. Richmond, Kathrin L. Dyer, Heather N. Zimmerman, Daniel W. Coyne, Marcos Rothstein, and Victoria J. Fraser

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A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing, Cinzia Cantacessi, Aaron R. Jex, Neil D. Young, Bronwyn E. Campbell, Anja Joachim, Matthew J. Nolan, Sahar Abubucker, Paul W. Sternberg, Shoba Ranganathan, Makedonka Mitreva, and Robin B. Gasser

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Massively parallel sequencing and analysis of the Necator americanus transcriptome, Cinzia Cantacessi, Makedonka Mitreva, Aaron R. Jex, Neil D. Young, Bronwyn E. Campbell, Ross S. Hall, Maria A. Doyle, Stuart A. Ralph, Elida M. Rabelo, Shoba Ranganathan, Paul W. Sternberg, Alex Loukas, and Robin B. Gasser

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Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, and Kirill A. Martemyanov

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Tiotropium bromide step-up therapy for adults with uncontrolled asthma, Mario Castro, Michael J. Walter, and et al

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Rapid activation of dormant presynaptic terminals by phorbol esters, Chun Y. Chang, Xiaoping Jiang, Krista L. Moulder, and Steven Mennerick

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Adducin 1 (alpha) Gly460Trp variant is associated with left ventricular geometry in Caucasians and African Americans: The HyperGEN Study, Krati Chauhan, Richard B. Devereux, D. C. Rao, Ulrich Broeckel, Charles C. Gu, Paul Hopkins, and Donna K. Arnett

siRNAs from miRNA sites mediate DNA methylation of target genes, Padmanabhan Chellappan, Jing Xia, Xuefeng Zhou, Shang Gao, Xiaoming Zhang, Gabriela Coutino, Franck Vazquez, Weixiong Zhang, and Hailing Jin

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Macaque parieto-insular vestibular cortex: Responses to self-motion and optic flow, Aihua Chen, Gregory C. DeAngelis, and Dora E. Angelaki

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A novel auxiliary subunit critical to BK channel function in caenorhabditis elegans, Bojun Chen, Qian Ge, Xiao-Ming Xia, Ping Liu, Sijie J. Wang, Haiying Zhan, Betty A. Eipper, and Zhao-Wen Wang

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Neoadjuvant endocrine therapy in primary breast cancer: Indications and use as a research tool, Yeehong Chia, M. J. Ellis, and Cynthia Ma

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Total raltegravir concentrations in cerebrospinal fluid exceed the 50-percent inhibitory concentration for wild-type HIV-1, David B. Clifford and et al

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Combined hip arthroscopy and limited open osteochondroplasty for anterior femoroacetabular impingement, John C. Clohisy, Lukas P. Zebala, Jeffrey J. Nepple, and Gail Pashos

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Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound, Jacquelynn J. Cook, Kristin R. Wildsmith, David B. Gilberto, Marie A. Holahan, Gene G. Kinney, Parker D. Mathers, Maria S. Michener, Eric A. Price, Mark S. Shearman, Adam J. Simon, Jennifer X. Wang, Guoxin Wu, Kevin E. Yarasheski, and Randall J. Bateman

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CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors, Joseph C. Corbo, Karen A. Lawrence, Marcus Karlstetter, Connie A. Myers, Musa Abdelaziz, William Dirkes, Karin Weigelt, Martin Seifert, Vladimir Benes, Lars G. Fritsche, Bernhard H.F. Weber, and Thomas Langmann

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Evaluation of a chromogenic agar for detection of group B streptococcus in pregnant women, Robin R. Craven, Carol J. Weber, Rebecca A. Jennemann, and W. Michael Dunne Jr.

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Growth modulation by means of anterior tethering resulting in progressive correction of juvenile idiopathic scoliosis: A case report, Charles H. Crawford and Lawrence G. Lenke

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Phospholipase C gamma 2 Is critical for development of a murine model of inflammatory arthritis by affecting actin dynamics in dendritic cells, Viviana Cremasco, Elisa Benasciutti, Marina Cella, Marina Kisseleva, Monica Croke, and Roberta Faccio

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A PPARalpha promoter variant impairs ERR-dependent transactivation and decreases mortality after acute coronary ischemia in patients with diabetes, Sharon Cresci, Janice M. Huss, Amber L. Beitelshees, Philip G. Jones, Matt R. Minton, Gerald W. Dorn II, Daniel P. Kelly, John A. Spertus, and Howard L. McLeod

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Promoter and Riboswitch Control of the Mg2+ Transporter MgtA from Salmonella enterica, Michael J. Cromie and Eduardo A. Groisman

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SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer’s disease, Carlos Cruchaga, John S. K. Kauwe, Kevin Mayo, Noah Spiegel, Sarah Bertelsen, Petra Nowotny, Aarti R. Shah, Richard Abraham, Paul Holligworth, Denise Harold, Michael M. Owen, Julie Williams, Simon Lovestone, Elaine R. Peskind, Ge Li, James B. Leverenz, Douglas Galasko, The Alzheimer's Disease Neuroimaging Initiative, John C. Morris, Anne M. Fagan, David M. Holtzman, and Alison M. Goate

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Virulence plasmid harbored by uropathogenic Escherichia coli functions in acute stages of pathogenesis, Corinne K. Cusumano, Chia S. Hung, Swaine L. Chen, and Scott J. Hultgren

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Lipids driving protein structure? Evolutionary adaptations in Kir channels, Nazzareno D'Avanzo, Wayland W.L. Chang, Shizhen Wang, Decha Enkvetchakul, and Colin G. Nichols

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Urine interleukin-6 is an early biomarker of acute kidney injury in children undergoing cardiac surgery, Paula Dennen, Christopher Altmann, Jonathan Kaufman, Christina L. Klein, Ana Andres-Hernando, Nilesh H. Ahuja, Charles L. Edelstein, Melissa A. Cadnapaphornchai, Angela Keniston, and Sarah Faubel

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Splenic injury during percutaneous nephrolithotomy: A case report with novel management technique, Alana C. Desai, Samay Jain, Brian M. Benway, Robert L. Grubb III, Daniel Picus, and Robert S. Figenshau

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Tuboovarian abscesses: Is size associated with duration of hospitalization & complications?, Jason DeWitt, Angela Reining, Jenifer E. Allsworth, and Jeffrey F. Peipert

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Charting the progression of disability in Parkinson disease: Study protocol for a prospective longitudinal cohort study, Leland E. Dibble, James T. Cavanaugh, Gammon M. Earhart, Terry D. Ellis, Matthew P. Ford, and Kenneth B. Foreman

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Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells, Hans H. Dietrich, Chuanxi Xiang, Byung H. Han, Gregory J. Zipfel, and David M. Holtzman

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Leishmania major survival in selective Phlebotomus papatasi sand fly vector requires a specific SCG-encoded lipophosphoglycan galactosylation pattern, Deborah E. Dobson, Shaden Kamhawi, Phillip Lawyer, Salvatore J. Turco, Stephen M. Beverley, and David L. Sacks

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It's not easy being green: The viridans group streptococci, with a focus on pediatric clinical manifestations, Christpher D. Doern and Carey-Ann D. Burnham

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Self versus environment motion in postural control, Kalpana Dokka, Robert V. Kenyon, Emily A. Keshner, and Konrad P. Kording

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Remember the source: Dissociating frontal and parietal contributions to episodic memory, David I. Donaldson, Mark E. Wheeler, and Steve E. Petersen

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Mechanisms of non-apoptotic programmed cell death in diabetes and heart failure, Gerald W. Dorn II

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Cerenkov radiation energy transfer (CRET) imaging: A novel method for optical imaging of PET isotopes in biological systems, Robin S. Dothager, Reece J. Goiffon, Erin Jackson, Scott Harpstrite, and David Piwnica-Worms

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Magnesium induces neuronal apoptosis by suppressing excitability, W. H. Dribben, L. N. Eisenman, and S. Mennerick

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Prevention of healthcare-associated Clostridium difficile infection: What works?, Erik R. Dubberke

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Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin, Alexis Dumortier, Andre-Dante Durham, Matteo Di Piazza, Sophie Vauclair, Ute Koch, Gisele Ferrand, Isabel Ferrero, Shadmehr Demehri, Lynda Li Song, Andrew G. Farr, Warren J. Leonard, Raphael Kopan, Lucio Miele, Daniel Hohl, Daniel Finke, and Freddy Radtke

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Inflammatory monocytes but not neutrophils are necessary to control infection with Toxoplasma gondii in mice, Ildiko R. Dunay, Anja Fuchs, and L. David Sibley

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Enhancement of anti-DIII antibodies by the C3d derivative P28 results in lower viral titers and augments protection in mice, Matthew D. Dunn, Shannon L. Rossi, Donald M. Carter, Matthew R. Vogt, Erin Mehlhop, Michael S. Diamond, and Ted M. Ross

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CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow, Kyle J. Eash, Adam M. Greenbaum, Priya K. Gopalan, and Daniel C. Link

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Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells, Brian T. Edelson, Wumesh KC, Richard Juang, Masako Kohyama, Loralyn A. Benoit, Paul A. Klekotka, Clara Moon, Jörn C. Albring, Wataru Ise, Drew G. Michael, Deepta Bhattacharya, Thaddeus S. Stappenbeck, Michael J. Holtzman, Sun-Sang J. Sung, Theresa L. Murphy, Kai Hildner, and Kenneth M. Murphy

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Improving prefrontal cortex function in schizophrenia through focused training of cognitive control, Bethany G. Edwards, Deanna M. Barch, and Todd S. Braver

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Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns, John R. Edwards, Anne H. O'Donnell, Robert A. Rollins, Heather E. Peckham, Clarence Lee, Maria H. Milekic, Benjamin Chanrion, Yutao Fu, Tao Su, Hanina Hibshoosh, Jay A. Gingrich, Fatemeh Haghighi, Robert Nutter, and Timothy H. Bestor

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p38δ mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis, Tatiana Efimova

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Multiple pathways of inhibition shape bipolar cell responses in the retina, Erika D. Eggers and Peter D. Lukasiewicz

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MHC class I–deficient natural killer cells acquire a licensed phenotype after transfer into an MHC class I–sufficient environment, Julie M. Elliott, Joseph A. Wahle, and Wayne M. Yokoyama

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Catalytic function of PLA2G6 is impaired by mutations associated with infantile neuroaxonal dystrophy but not dystonia-parkinsonism, Laura A. Engel, Zheng Jing, Daniel E. O’Brien, Mengyang Sun, and Paul T. Kotzbauer

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Gene-expression profiling for rejection surveillance after cardiac transplantation, Gregory A. Ewald and et al

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Next-generation sequencing identifies the natural killer cell microRNA transcriptome, Todd A. Fehniger, Todd Wylie, Elizabeth Germino, Jeffrey W. Leong, Vincent J. Magrini, Sunita Koul, Catherine R. Keppel, Stephanie E. Schneider, Daniel C. Koboldt, Ryan P. Sullivan, Michael E. Heinz, Seth D. Crosby, Rakesh Nagarajan, Giridharan Ramsingh, Daniel C. Link, Timothy J. Ley, and Elaine R. Mardis

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Multiplexed echo planar imaging for sub-second whole brain fMRI and fast diffusion imaging, David A. Feinberg, Steen Moeller, Stephen M. Smith, Edward Auerbach, Sudhir Ramanna, Matt F. Glasser, Karla L. Miller, Kamil Ugurbil, and Essa Yacoub

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Major depression and the metabolic syndrome, Debra L. Foley, Katherine I. Morley, Pamela A.F. Madden, Andrew C. Heath, John B. Whitfield, and Nicholas G. Martin

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Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells, Sonya G. Fonseca, Shinsuke Ishigaki, Christine M. Oslowski, Simin Lu, Kathryn L. Lipson, Rajarshi Ghosh, Emiko Hayashi, Hisamitsu Ishihara, Yoshitomo Oka, M. Alan Permutt, and Fumihiko Urano

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Structural homology between the C-terminal domain of the PapC usher and its plug, Bradley Ford, Ana Toste Rêgo, Timothy J. Ragan, Jerome Pinkner, Karen Dodson, Paul C. Driscoll, Scott Hultgren, and Gabriel Waksman

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Statistical design of personalized medicine interventions: The Clarification of Optimal Anticoagulation through Genetics (COAG) trial, Benjamin French, Jungnam Joo, Nancy L. Geller, Stephen E. Kimmel, Yves Rosenberg, Jeffrey L. Anderson, Brian F. Gage, Julie A. Johnson, Jonas H. Ellenberg, and COAG Investigators

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Age-related synaptic loss of the medial olivocochlear efferent innervation, Benjamin Fu, Colleen Le Prell, Dwayne Simmons, Debin Lei, Angela Schrader, Amelia B. Chen, and Jianxin Bao

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Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking, Rodrigo A. Fuentealba, Qiang Liu, Juan Zhang, Takahisa Kanekiyo, Xiaoyan Hu, Jin-Moo Lee, Mary Jo LaDu, and Guojun Bu

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VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans, Keiko Fujikawa, Takeshi Iwata, Kaoru Inoue, Masakazu Akahori, Hanako Kadotani, Masahiro Fukaya, Masahiko Watanabe, Qing Chang, Edward M. Barnett, and Wojciech Swat

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Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes, Kei Fujimoto, Eric L. Ford, Hung Tran, Burton M. Wice, Seth D. Crosby, Gerald W. Dorn II, and Kenneth S. Polonsky

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The impact of packed red blood cell transfusion on clinical outcomes in patients with septic shock treated with early goal directed therapy, Brian M. Fuller, Mithil Gajera, Christa Schorr, David Gerber, R. Phillip Dellinge, Joseph Parrillo, and Sergio Zanotti

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Parallel input channels to mouse primary visual cortex, Enquan Gao, Gregory C. DeAngelis, and Andreas Burkhalter

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Identification of hookworm DAF-16/FOXO response elements and direct gene targets, Xin Gao, Zhengyuan Wang, John Martin, Sahar Abubucker, Xu Zhang, Makedonka Mitreva, and John M. Hawdon

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To-and-fro murmur in the young due to major congenital cardiac defects: Is cardiac auscultation obsolete?, Avihu Z. Gazit, Gautam K. Singh, and Mark C. Johnson

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Dyskerin ablation in mouse liver inhibits rRNA processing and cell division, Jingping Ge, David A. Rudnick, Jun He, Dan L. Crimmins, Jack H. Ladenson, Monica Bessler, and Philip J. Mason

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Orthopaedic surgeons and the medical device industry: The threat to scientific integrity and the public trust, Richard H. Gelberman, David Samson, Sohail K. Mirza, John J. Callaghan, and Vincent D. Pellegrini

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Gene–environment interactions at nucleotide resolution, Justin Gerke, Kim Lorenz, Shelina Ramnarine, and Barak Cohen

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Multicenter study of clinical performance of the 3M rapid detection RSV test, Christine C. Ginocchio, Ella Swierkosz, Alexander J. McAdam, Mario Marcon, Gregory A. Storch, Alexandra Valsamakis, Stefan Juretschko, José Romero, and Belinda Yen-Lieberman

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Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo, Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J. Holtzman, and Marco Colonna

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Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease, Alison M. Goate, Carlos Cruchaga, Petra Nowotny, John C. Morris, Kevin Mayo, and et al.

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RET signaling is required for survival and normal function of nonpeptidergic nociceptors, Judith P. Golden, Masato Hoshi, Mohammed A. Nassar, Hideki Enomoto, John N. Wood, Jeffrey Milbrandt, Robert W. Gereau IV, Eugene M. Johnson Jr, and Sanjay Jain

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Human mucosal associated invariant T cells detect bacterially infected cells, Marielle C. Gold, Stefanie Cerri, Susan Smyk-Pearson, Meghan E. Cansler, Todd M. Vogt, Jacob Delepine, Ervina Winata, Gwendolyn M. Swarbrick, Wei-Jen Chua, Yik Y. L. Yu, Olivier Lantz, Matthew S. Cook, Megan D. Null, David B. Jacoby, Melanie J. Harriff, Deborah A. Lewinsohn, Ted H. Hansen, and David M. Lewinsohn

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Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation, Veronica Gomez-Godinez, Tao Wu, Adria J. Sherman, Christopher S. Lee, Lih-Huei Liaw, You Zhongsheng, Kyoko Yokomori, and Michael W. Berns

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Multiple interaction domains in FtsL, a protein component of the widely conserved bacterial FtsLBQ cell division complex, Mark D. Gonzalez, Esra A. Akbay, Dana Boyd, and Jon Beckwith

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Nurturing the genome: A-type lamins preserve genomic stability, Ignacio Gonzalez-Suarez and Susana Gonzalo

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Sit and Stay a While: How BfiSR Controls Irreversible Attachment in Pseudomonas aeruginosa Biofilms, Andrew L. Goodman

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The Haemophilus influenzae HMW1C protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin, Susan Grass, Cheryl F. Lichti, R. Reid Townsend, Julia Gross, and Joseph W. St. Geme III

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Developmental origin of preBötzinger complex respiratory neurons, Paul A. Gray, John A. Hayes, Guang Y. Ling, Isabel Llona, Srinivasan Tupal, Maria C.D. Picardo, Sarah E. Ross, Tsutomu Hirata, Joshua G. Corbin, Jaime Eugenín, and Christopher A. Del Negro

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Brain specificity of diffuse optical imaging: improvements from superficial signal regression and tomography, Nicholas M. Gregg, Brian R. White, Benjamin W. Zeff, Andrew J. Berger, and Joseph P. Culver

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Serological evidence of human klassevirus infection, Alexander L. Greninger, Lori Holtz, Gagandeep Kang, Donald Ganem, David Wang, and Joseph L. DeRisi