The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2010

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State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation, Dick Wu, Kelli Delaloye, Mark A. Zaydman, Ali Nekouzadeh, Yoram Rudy, and Jianmin Cui

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Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia, Zhifu Xiang, Hui Luo, Jacqueline E. Payton, Jennifer Cain, Timothy J. Ley, Joseph T. Opferman, and Michael H. Tomasson

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Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron DiAntonio, and Catherine A. Collins

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Relationship between complex and simple spike activity in macaque caudal vermis during three-dimensional vestibular stimulation, Tatyana Yakusheva, Pablo M. Blazquez, and Dora E. Angelaki

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NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis, Chang Yang, Kathleen McCoy, Jennifer L. Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, and Deborah Veis Novack

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Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis, Jingxuan Yang, Michael Meyer, Anna-Katharina Müller, Friederike Böhm, Richard Grose, Tina Dauwalder, Francois Verrey, Manfred Kopf, Juha Partanen, Wilhelm Bloch, David M. Ornitz, and Sabine Werner

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Application of X STOP device in the treatment of lumbar spinal stenosis, Xiaobin Yi and Bradley McPherson

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Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas, Anas Younes, Nancy L. Bartlett, John P. Leonard, Dana A. Kennedy, Carmel M. Lynch, Eric L. Sievers, and Andres Forero-Torres

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Behavioral consequences of NMDA antagonist-induced neuroapoptosis in the infant mouse brain, Carla M. Yuede, David F. Wozniak, Catherine E. Creeley, George T. Taylor, John W. Olney, and Nuri B. Farber

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Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice, Pin Yue, Zhouji Chen, Fatiha Nassir, Carlos Bernal-Mizrachi, Brian Finck, Salman Azhar, and Nada A. Abumrad

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Ribosomal RNA diversity predicts genome diversity in gut bacteria and their relatives, Jesse R. Zaneveld, Catherine Lozupone, Jeffrey I. Gordon, and Rob Knight

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Conservation and divergence of microRNAs and their functions in Euphorbiaceous plants, Changying Zeng, Wenquan Wang, Yun Zheng, Xin Chen, Weiping Bo, Shun Song, Weixiong Zhang, and Ming Ping

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Regulation of cell death and epileptogenesis by the mammalian target of rapamycin (mTOR): A double-edged sword?, Ling-Hui Zeng, Sharon McDaniel, Nicholas R. Rensing, and Michael Wong

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Multiple distinct small RNAs originate from the same microRNA precursors, Weixiong Zhang, Shang Gao, Xuefeng Zhou, Jing Xia, Padmanabhan Chellappan, Xiang Zhou, Xiaoming Zhang, and Hailing Jin

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Diagnosis of pulmonary tuberculosis among asymptomatic HIV+ patients in Guangxi, China, Yao Zhang, Lan Yu, Zhi-rong Tang, Shao-biao Huang, Yuan-jia Zheng, Zhi-hao Meng, Kai Sun, Li-ming Wang, Ray Y. Chen, and Fu-jie Zhang

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Gamma-secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin, Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, and Raphael Kopan

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Glycine311, a determinant of paxilline block in BK channels: A novel bend in the BK S6 helix, Yu Zhou, Qiong-Yao Tang, Xiao-Ming Xia, and Christopher J. Lingle

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Herbaspirillum species bacteremia in a pediatric oncology patient, Edward D. Ziga, Todd Druley, and Carey-Ann D. Burnham

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Inappropriate empiric antifungal therapy for candidemia in the ICU and hospital resource utilization: a retrospective cohort study, Marya D. Zilberberg, Marin H. Kollef, Heather Arnold, Andrew Labelle, Scott T. Micek, Smita Kothari, and Andrew F. Shorr

Submissions from 2009

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Mutations in ampG and lytic transglycosylase genes affect the net release of peptidoglycan monomers from Vibrio fischeri, Dawn M. Adin, Jacquelyn T. Engle, William E. Goldman, Margaret J. McFall-Ngai, and Eric V. Stabb

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Item response modeling of DSM-IV mania symptoms in two representative US epidemiological samples, A. Agrawal, J. I. Nurnberger Jr., and M. T. Lynskey

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Cancer stem cells - from initiation to elimination, how far have we reached?, Kamal Akhtar, Wendy Bussen, and Shaun P. Scott

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Physical and sexual violence and incident sexually transmitted infections, Jenifer E. Allsworth, Mallika Anand, Colleen A. Redding, and Jeffrey F. Peipert

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Classification of nonenzymatic homologues of protein kinases, K. Anamika, K. R. Abhinandan, K. Deshmukh, and N. Srinivasan

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Copper-64 radiopharmaceuticals for PET imaging of cancer: Advances in preclinical and clinical research, Carolyn J. Anderson and Riccardo Ferdani

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αA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice, Usha P. Andley

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Exploring the feasibility of a meta-structure for DSM-V and ICD-11: Could it improve utility and validity, G. Andrews, D. P. Goldberg, R. F. Krueger, W. T. Carpenter Jr, S. E. Hyman, P. Sachdev, and D. S. Pine

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Heritability of risk-taking in adolescence: A longitudinal twin study, Andrey P. Anokhin, Simon Golosheykin, Julia Grant, and Andrew C. Heath

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Epistatic interactions of CDKN2B-TCF7L2 for risk of type 2 diabetes and of CDKN2B-JAZF1 for triglyceride/high-density lipoprotein ratio longitudinal change: Evidence from the Framingham Heart Study, Ping An, Mary Feitosa, Shamika Ketkar, Avril Adelman, Shiow Lin, Ingrid Borecki, and Michael Province

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Difficulty in diagnosing surgical site infection after arthroscopy in developing countries, Anucha Apisarnthanarak, Siriporn Wittayachanyapong, Pranee Sitaposa, Kanokporn Thongphubeth, Hilary Babcock, and Victoria J. Fraser

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Protocol for the BAG-RECALL clinical trial: A prospective, multi-center, randomized, controlled trial to determine whether a bispectral index-guided protocol is superior to an anesthesia gas-guided protocol in reducing intraoperative awareness with explicit recall in high risk surgical patients, Michael S. Avidan, Ben J. Palanca, David Glick, Eric Jacobsohn, Alex Villafranca, Michael O'Connor, and George A. Mashour

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Microbiological, clinical, and surgical features of fungal prosthetic joint infections: A multi-institutional experience, Khalid Azzam, Javad Parvizi, Donald Jungkind, Arlen Hanssen, Thomas Fehring, Bryan Springer, Kevin Bozic, Craig Della Valle, Luis Pulido, and Robert Barrack

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Transcriptomic analysis of the entomopathogenic nematode Heterorhabditis bacteriophora TTO1, Xiaodong Bai, Byron J. Adams, Todd A. Ciche, Sandra Clifton, Randy Gaugler, Saskia A. Hogenhout, John Spieth, Paul W. Sternberg, Richard K. Wilson, and Parwinder S. Grewal

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Chitinases are essential for sexual development but not vegetative growth in cryptococcus neoformans, Lorina G. Baker, Charles A. Sprecht, and Jennifer K. Lodge

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Requirements of Hsp104p activity and Sis1p binding for propagation of the [RNQ+] prion, J. Patrick Bardill, Jennifer E. Dulle, Jonathan R. Fisher, and Heather L. true

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Detecting heterozygosity in shotgun genome assemblies: Lessons from obligately outcrossing nematodes, Antoine Barrière, Shiaw-Pyng Yang, Elizabeth Pekarek, Cristel G. Thomas, Eric S. Haag, and Ilya Ruvinsky

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Transport characteristics of nanoparticle-based ferrofluids in a gel model of the brain, Soubir Basak, David Brogan, Hans Dietrich, Roger Ritter, Ralph G. Dacey, and Pratim Biswas

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The membrane proteome of the mouse lens fiber cell, Steven Bassnett, Phillip A. Wilmarth, and Larry L. David

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An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ, Fariba Behbod, Frances S. Kittrell, Heather LaMarca, David Edwards, Sofia Kerbawy, Jessica C. Heestand, Evelin Young, Purna Mukhopadhyay, Hung-Wen Yeh, D Craig Allred, Min Hu, Kornelia Polyak, Jeffrey M. Rosen, and Daniel Medina

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An intact urease assembly pathway is required to compete with NikR for nickel ions in Helicobacter pylori, Erin L. Benanti and Peter T. Chivers

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Selective versus nonselective arterial clamping during laparoscopic partial nephrectomy: Impact upon renal function in the setting of a solitary kidney in a porcine model, Brian M. Benway, Geneva Baca, Sam B. Bhayani, Nitin A. Das, Matthew D. Katz, Dilmer L. Diaz, Keegan L. Maxwell, Khalid H. Badwan, Michael R. Talcott, Helen Liapis, Jose M. Cabello, Ramakrishna Venkatesh, and Robert S. Figenshau

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Open versus laparoscopic retroperitoneal lymph node dissection: Assessing adequacy of dissection in a porcine model, Brian M. Benway, Dilmer L. Diaz, Matthew D. Katz, Itay Y. Vardi, Naeem T. Chavla, Khalid H. Badwan, Keegan L. Maxwell, Geneva Baca, Peter A. Humphrey, Sam B. Bhayani, and Robert S. Figenshau

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Blast-related brain injury: imaging for clinical and research applications: report of the 2008 St. Louis workshop, Tammie L.S Benzinger, David Brody, Mark A. Mintun, R. Gilbert Jost, Karen Kharasch, Philip V. Bayly, Maurizio Corbetta, Joseph P. Culver, Evan D. Kharasch, Christine Mac Donald, Daniel Marcus, Steve Petersen, Kathy J. Pierce, Jose Pineda, Joshua S. Shimony, Victor Sheng-Kwei Song, Gregory Zipfel, and et al

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Epidermodysplasia verruciform-like lesions in an HIV patient, David R. Berk, Anna L. Bruckner, and Dongsi Lu

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The transcriptional cofactor Nab2 Is induced by TGF-beta and suppresses fibroblast activation: Physiological roles and impaired expression in scleroderma, Swati Bhattacharyya, Jun Wei, Denisa S. Melichian, Jeffrey Milbrandt, Kazuhiko Takehara, and John Varga

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Immunopurification of pathological prion protein aggregates, Emiliano Biasini, Laura Tapella, Susanna Mantovani, Matteo Stravalaci, Marco Gobbi, David A. Harris, and Roberto Chiesa

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Detection and characterization of the fimbrial sfp cluster in enterohemorrhagic Escherichia coli O165:H25/NM isolates from humans and cattle, Martina Bielaszewska, Rita Prager, Liz Vandivinit, Anne Musken, Alexander Mellmann, Nicholas J. Holt, Phillip I. Tarr, Helge Karch, and Wenlan Zhang

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Further analysis of previously implicated linkage regions for Alzheimer's disease in affected relative pairs, Elin S. Blom, Vilmantas Giedraitis, Sampath Arepalli, Marian L. Hamshere, Omanma Adighibe, Alison Goate, Julie Williams, Lars Lannfelt, John Hardy, Fabienne Wavrant-De Vrièze, and Anna Glaser

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Patient satisfaction in postmenopausal women treated with a weekly bisphosphonate transitioned to once-monthly ibandronate, Sydney Lou Bonnick, Stuart Silverman, S. Bobo Tanner, Mark Martens, Gloria Bachmann, Joseph D. Kohles, and Roberto Civitelli

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Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity, Marielle Boonen, Peter Vogel, Kenneth A. Platt, Nancy Dahms, and Stuart Kornfeld

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The completion of the Mammalian Gene Collection (MGC), Michael Brent, Laura Langton, Charles L.G. Comstock, Michael Stevens, Chaochun Wei, Marijke J. van Baren, and et al

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang

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Key role of T cell defects in age-related vulnerability to West Nile virus, James D. Brien, Jennifer L. Uhrlaub, Alec Hirsch, Clayton A. Wiley, and Janko Nikolich-Zugich

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Test-retest reliability of web-based retrospective self-report of tobacco exposure and risk, Janet Brigham, Christina N. Lessov-Schlaggar, Harold S. Javitz, Ruth E. Krasnow, Mary McElroy, and Gary E. Swan

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Helminth genomics: The implications for human health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, and Sara Lustigman

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αII-spectrin breakdown product cerebrospinal fluid exposure metrics suggest differences in cellular injury mechanisms after severe traumatic brain injury, Gretchen M. Brophy, Jose A. Pineda, Linda Papa, Stephen B. Lewis, Alex B. Valadka, H. Julia Hannay, Shelley C. Heaton, Jason A. Demery, Ming Cheng Liu, Joseph J. Tepas III, Andrea Gabrielli, Steven Robicsek, Kevin K.W Wang, Claudia S. Robertson, and Ronald L. Hayes

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Dorsal root ganglion neurons react to semaphorin 3A application through a biphasic response that requires multiple myosin II isoforms, Jacquelyn A. Brown, Robert B. Wysolmerski, and Paul C. Bridgman

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Factors influencing the implementation of school wellness policies in the United States, 2009, Elizabeth L. Budd, Cynthia Schwarz, Byron W. Yount, and Debra Haire-Joshu

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Patellar resurfacing compared with nonresurfacing in total knee arthroplasty: A concise follow-up of a randomized trial, R. Stephen Burnett, Julienne L. Boone, Seth D. Rosenzweig, and Karen Steger-May

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Antimicrobial therapy for acute colonic diverticulitis, Matthew C. Byrnes and John E. Mazuski

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Robotic-assisted partial nephrectomy: Surgical technique using a 3-arm approach and sliding-clip renorrhaphy, Jose M. Cabello, Brian M. Benway, and Sam B. Bhayani

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A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease, Ken Cadwell, Khushbu K. Patel, Masaaki Komatsu, Herbert W. Virgin IV, and Thaddeus S. Stappenbeck

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Chimeric IgH-TCR/ translocations in T lymphocytes mediated by RAG, Elsa Callen, Sam Bunting, Ching-Yu Huang, Michael J. Difilippantonio, Nancy Wong, Bernard Khor, Grace Mahowald, Michael J. Kruhlak, Thomas Ried, Barry P. Sleckman, and Andre Nussenzweig

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Impact of an antimicrobial utilization program on antimicrobial use at a large teaching hospital: A randomized controlled trial, Bernard C. Camins, Mark D. King, Jane B. Wells, Heidi L. Googe, Manish Patel, Ekaterina V. Kourbatova, and Henry M. Blumberg

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In vitro and murine efficacy and toxicity studies of nebulized SCC1, a methylated caffeine-silver(I) complex, for treatment of pulmonary infections, Carolyn L. Cannon, Lisa A. Hogue, Ravy K. Vajravelu, George H. Capps, Aida Ibricevic, Khadijah M. Hindi, Aysegul Kascatan-Nebioglu, Michael J. Walter, Steven L. Brody, and Wiley J. Youngs

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The psychoses: Cluster 3 of the proposed meta-structure for DSM-V and ICD-11, W. T. Carpenter Jr., J. R. Bustillo, G. K. Thaker, J. van Os, R. F. Krueger, and M. J. Green

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Recombinant Listeria monocytogenes expressing a cell wall-associated listeriolysin O is weakly virulent but immunogenic, Javier A. Carrero, Boris Calderon, Hector Vivanco-Cid, and Emil R. Unanue

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Risky sexual behaviors and sexually transmitted diseases: a comparison study of cocaine-dependent individuals in treatment versus a community-matched sample, Patricia A. Cavazos-Rehg, Edward L. Spitznagel, Mario Schootman, Jaime R. Strickland, Stephanie E. Afful, Linda B. Cottler, and Laura Jean Bierut

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Plumbing the depths of urinary tract obstruction by using murine models, Feng Chen

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KirBac1.1: It's an inward rectifying potassium channel, Wayland W.L. Cheng, Decha Enkvetchakul, and Colin G. Nichols

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G protein subunit dissociation and translocation regulate cellular response to receptor stimulation, Mariangela Chisari, Deepak Kumar Saini, Joon-Ho Cho, Vani Kalyanaraman, and N. Gautam

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Activated by different signals, the PhoP/PhoQ two-component system differentially regulates metal uptake, Eunna Choi, Eduardo A. Groisman, and Dongwoo Shin

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Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex, Hyongi Chon, Alex Vassilev, Melvin L. DePamphilis, Yingming Zhao, Junmei Zhang, Peter M. Burgers, Robert J. Crouch, and Susana M. Cerritelli

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Identification of deleterious mutations within three human genomes, Sung Chun and Justin C. Fay

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Task control signals in pediatric Tourette syndrome show evidence of immature and anomalous functional activity, Jessica A. Church, Kristin K. Wenger, Nico U.F. Dosenbach, Francis M. Miezin, Steven E. Petersen, and Bradley L. Schlaggar

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A genomic score prognostic of outcome in trauma patients, J. P. Cobb and et al.

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Developmental course of autistic social impairment in males, John N. Constantino, Anna M. Abbacchi, Patricia D. Lavesser, Hannah Reed, Leah Givens, Lily Chang, Teddi Gray, Maggie Gross, Yi Zhang, and Richard D. Todd

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Adenylyl cyclases 1 and 8 initiate a presynaptic homeostatic response to ethanol treatment, Alana C. Conti, James W. Maas Jr., Krista L. Moulder, Xiaoping Jiang, Bhumy A. Dave, Steven Mennerick, and Louis J. Muglia

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Comparative effects of heterologous TRPV1 and TRPM8 expression in rat hippocampal neurons, Devon C. Crawford, Krista L. Moulder, Robert W. Gereau IV, Gina M. Story, and Steven Mennerick

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Power and false-positive rates for the restricted partition method (RPM) in a large candidate gene data set, Robert Culverhouse, Wu Jin, Carol H. Jin, Anthony L. Hinrichs, and Brian K. Suarez

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Topics in biomedical optics: Introduction to the feature issue, Joseph P. Culver, Wolfgang Drexler, Rebekah A. Drezek, Irene Georgakoudi, Elizabeth M C Hillman, and Rebecca Richards-Kortum

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Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses, L Adrienne Cupples, Joseph Beyene, Heike Bickeböller, E Warwick Daw, M Daniele Fallin, W James Gauderman, Saurabh Ghosh, Ellen L. Goode, Elizabeth R. Hauser, Anthony Hinrichs, Jack W. Kent Jr, Lisa J. Martin, Maria Martinez, Rosalind J. Neuman, Michael Province, Silke Szymczak, Marsha A. Wilcox, Andreas Ziegler, Jean W. MacCluer, and Laura Almasy

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Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy, Dru S. Dace, Aslam A. Khan, Jennifer L. Stark, Jennifer Kelly, Anne H. Cross, and Rajendra S. Apte

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Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7, Stephane Daffis, Mehul S. Suthar, Kristy J. Szretter, Michael Gale Jr., and Michael S. Diamond

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Lung and heart-lung transplantation, Hiroshi Date and Stuart C. Sweet

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Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression, Cristin D. Davidson, Nafeeza F. Ali, Mathew C. Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S. Ory, Marie T. Vanier, and Steven U. Walkley

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Proteomic comparison of Entamoeba histolytica and Entamoeba dispar and the role of E. histolytica alcohol dehydrogenase 3 in virulence, Paul H. Davis, Minghe Chen, Xiaochun Zhang, C. Graham Clark, R. Reid Townsend, and Samuel L. Stanley Jr.

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A framework for analyzing both linkage and association: An analysis of Genetic Analysis Workshop 16 simulated data, E Warwick Daw, Jevon Plunkett, Mary Feitosa, Xiaoyi Gao, Andrew Van Brunt, Duanduan Ma, Jacek Czajkowski, Michael A. Province, and Ingrid Borecki

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Considering usual medical care in clinical trial design, Liza Dawson, Deborah A. Zarin, Ezekiel J. Emanuel, Lawrence M. Friedman, Bimal Chaudhari, and Steven N. Goodman

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Should burden of disease estimates include cannabis use as a risk factor for psychosis?, Louisa Degenhardt, Wayne D. Hall, Michael Lynskey, John McGrath, Jennifer McLaren, Bianca Calabria, Harvey Whiteford, and Theo Vos

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Depth sensitivity and image reconstruction analysis of dense imaging arrays for mapping brain function with diffuse optical tomography, Hamid Dehghani, Brian R. White, Benjamin W. Zeff, Andrew Tizzard, and Joseph P. Culver

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Skin-derived TSLP triggers progression from epidermal- barrier defects to asthma, Shadmehr Demehri, Mitsuru Morimoto, Michael J. Holtzman, and Raphael Kopan

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Mechanisms of evasion of the type i interferon antiviral response by flaviviruses, Michael S. Diamond

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Virus and host determinants of West Nile virus pathogenesis, Michael S. Diamond

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Umbilical artery Doppler indices in small for gestational age fetuses: Correlation with adverse outcomes and placental abnormalities, Jeffrey M. Dicke, Phyllis Huettner, Sida Yan, Anthony Odibo, and Frederick T. Kraus

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Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death, Abhinav Diwan, Scot J. Matkovich, Qunying Yuan, Wen Zhao, Atsuko Yatani, Joan Heller Brown, Jeffrey D. Molkentin, Evangelia G. Kranias, and Gerald W. Dorn II

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Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation, Lindzy F. Dodson, Jonathan S. Boomer, Christine M. Deppong, Dulari D. Shah, Julia Sim, Traci L. Bricker, John H. Russell, and Jonathan M. Green

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Polarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways, Maribel Donoso, Jorge Cancino, Jiyeon Lee, Peter van Kerkhof, Claudio Retamal, Guojun Bu, Alfonso Gonzalez, Alfredo Cáceres, and María-Paz Marzolo

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A role for dynein in the inhibition of germ cell proliferative fate, Maia Dorsett and Tim Schedl

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Multicenter study of the impact of community-onset Clostridium difficile infection on surveillance for C. difficile infection, Erik R. Dubberke, Anne M. Butler, Bala Hota, Yosef M. Khan, Julie E. Mangino, Jeanmarie Mayer, Kyle J. Popovich, Kurt B. Stevenson, Deborah S. Yokoe, L Clifford McDonald, John Jernigan, and Victoria J. Fraser