The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2007
Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury, David L. Brody, Christine Mac Donald, Chad C. Kessens, Carla Yuede, Maia Parsadanian, Mike Spinner, Eddie Kim, Katherine E. Schwetye, David M. Holtzman, and Philip V. Bayly
Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury, Sarah L. Brown, Terrence E. Riehl, Monica R. Walker, Michael J. Geske, Jason M. Doherty, William F. Stenson, and Thaddeus S. Stappenbeck
β2-Chimaerin in cancer signaling: Connecting cell adhesion and MAP kinase activation, Stephen P. Bruinsma and Thomas J. Baranski
Nuclear receptors PPARβ/δ and PPARα direct distinct metabolic regulatory programs in the mouse heart, Eileen M. Burkhart, Nandakumar Sambandam, Xianlin Han, Richard W. Gross, Michael Courtois, Carolyn M. Gierasch, Kooresh Shoghi, Michael J. Welch, and Daniel P. Kelly
A population-based investigation of invasive vancomycin-resistant enterococcus infection in metropolitan Atlanta, Georgia, and predictors of mortality, Bernard C. Camins, Monica M. Farley, John J. Jernigan, Susan M. Ray, James P. Steinberg, and Henry M. Blumberg
Zoonotic orthopoxviruses encode a high-affinity antagonist of NKG2D, Jessica A. Campbell, David S. Trossman, Wayne M. Yokoyama, and Leonidas N. Carayannopoulos
Species selectivity of mixed-lineage leukemia/trithorax and HCF proteolytic maturation pathways, Francesca Capotosti, James J.-D. Hsieh, and Winship Herr
Comparisons of mutants lacking the golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania major, Althea A. Capul, Suzanne Hickerson, Tamara Barron, Salvatore J. Turco, and Stephen M. Beverley
Non-neurologic complications following surgery for adolescent idiopathic scoliosis, Leah Y. Carreon, Rolando M. Puno, Lawrence G. Lenke, N. Stephen Richards, Daniel J. Sucato, John B. Emans, and Mark A. Erickson
Brain fatty acid synthase activates PPARa to maintain energy homeostasis, Manu V. Chakravarthy, Yimin Zhu, Miguel Lopez, Li Yin, David F. Wozniak, Trey Coleman, Zhiyuan Hu, Michael Wolfgang, Antonio Vidal-Puig, M. Daniel Lane, and Clay F. Semenkovich
PolyScan: An automatic indel and SNP detection approach to the analysis of human resequencing data, Ken Chen, Michael D. McLellan, Li Ding, Michael C. Wendl, and Yumi Kasai
The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the presence of PCNA, Olga Chilkova, Peter Stenlund, Isabelle Isoz, Carrie M. Stith, Pawel Grabowski, Else-Britt Lundstrom, Peter M. Burgers, and Erik Johansson
A galvanizing story—Protein stability and zinc homeostasis, Peter T. Chivers
Periacetabular osteotomy for the treatment of acetabular dysplasia associated with major aspherical femoral head deformities, John C. Clohisy, Ryan M. Nunley, Madelyn C. Curry, and Perry L. Schoenecker
The measurement and analysis of age-related changes in Caenorhabditis elegans, James J. Collins, Cheng Huang, Stacie Hughes, and Kerry Kornfeld
Genetic Analysis Workshop 15: Gene expression analysis and approaches to detecting multiple functional loci, Heather J. Cordell, Mariza de Andrade, Marie-Claude Babron, Christopher W. Bartlett, Joseph Beyene, Heike Bickeböller, Robert Culverhouse, L Adrienne Cupples, E Warwick Daw, Josee Dupuis, Catherine T. Falk, Saurabh Ghosh, Katrina A. Goddard, Ellen L. Goode, Elizabeth R. Hauser, Lisa J. Martin, Maria Martinez, Kari E. North, Nancy L. Saccone, Silke Schmidt, William Tapper, Duncan Thomas, David Tritchler, Veronica J. Vieland, Ellen M. Wijsman, Marsha A. Wilcox, John S. Witte, Qiong Yang, Andreas Ziegler, Laura Almasy, and Jean W. MacCluer
The pathogenic fungus Cryptococcus neoformans expresses two functional GDP-mannose transporters with distinct expression patterns and roles in capsule synthesis, Tricia R. Cottrell, Cara L. Griffith, Hong Liu, Ashley A. Nenninger, and Tamara L. Doering
Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms, Stephane Daffis, Melanie A. Samuel, Brian C. Keller, Michael Gale Jr., and Michael S. Diamond
Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival, Antara Datta, Lee Silverman, Andrew J. Phipps, Hajime Hiraragi, Lee Ratner, and Michael D. Lairmore
Computational identification and functional validation of regulatory motifs in cartilage-expressed genes, Sherri R. Davies, Li-Wei Chang, Debabrata Patra, Xiaoyun Xing, Karen Posey, Jacqueline Hecht, Gary D. Stormo, and Linda J. Sandell
The feasibility of oligogenic combined segregation and linkage analysis in CEPH pedigrees, E Warwick Daw and Robert Yu
Frequent gain and loss of functional transcription factor binding sites, Scott W. Doniger and Justin C. Fay
The γ/σ1 and α/σ2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site, Balraj Doray, Intaek Lee, Jane Knisely, Guojun Bu, and Stuart Kornfeld
Severity of Clostridium difficile-associated disease (CDAD) in allogeneic stem cell transplant recipients: Evaluation of a CDAD severity grading system, Erik R. Dubberke, Justin Sadhu, Robert Gatti, Kimberly A. Reske, John F. DiPersio, Steven M. Devine, and Victoria J. Fraser
Clustering of eating disorder symptoms in a general population female twin sample: A latent class analysis, Alexis E. Duncan, Kathleen K. Bucholz, Rosalind J. Neuman, Arpana Agrawal, Pamela A F Madden, and Andrew C. Heath
Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycines, Axel A. Elling, Makedonka Mitreva, Justin Recknor, Xiaowu Gai, John Martin, Thomas R. Maier, Jeffrey P. McDermott, Tarek Hewezi, David McK Bird, Eric L. Davis, Richard S. Hussey, Dan Nettleton, James P. McCarter, and Thomas J. Baum
The effect of compliance on the impact of mass drug administration for elimination of lymphatic filariasis in Egypt, Maged El Setouhy, Khaled M. Abd Elaziz, Hanan Helmy, Hoda A. Farid, Hussein A. Kamal, Reda M.R. Ramzy, William D. Shannon, and Gary J. Weil
Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains, Decha Enkvetchakul, Iana Jeliazkova, Jaya Bhattacharyya, and Colin G. Nichols
A critical appraisal of molecular xenomonitoring as a tool for assessing progress toward elimination of lymphatic filariasis, Hoda A. Farid, Zakariya S. Morsy, Hanan Helmy, Reda M.R. Ramzy, Maged El Setouhy, and Gary J. Weil
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial, Thomas Ferkol and et al
Persistence of Brugia malayi DNA in vector and non-vector mosquitoes: Implications for xenomonitoring and transmission monitoring of lymphatic filariasis, Peter Fischer, Sara M. Erickson, Kerstin Fischer, Jeremy F. Fuchs, Ramakrishna U. Rao, Bruce M. Christensen, and Gary J. Weil
Ventilator-associated pneumonia in neonatal and pediatric intensive care unit patients, Elizabeth Foglia, Mary Dawn Meier, and Alexis Elward
Impaired mononuclear cell immune function in extreme obesity is corrected by weight loss, Luigi Fontana, J. Christopher Eagon, Marco Colonna, and Samuel Klein
Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk, Luigi Fontana, Timothy E. Meyer, Samuel Klein, and John O. Holloszy
Genetics of body mass stability and risk for chronic disease: A 28-year longitudinal study, Carol E. Franz, MIchael D. Grant, Kristen C. Jacobson, William S. Kremen, Seth A. Eisen, Hong Xian, James Romeis, Heather Thompson-Brenner, and Michael J. Lyons
ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity, Rodrigo A. Fuentealba, Maria Ines Barría, Jiyeon Lee, Judy Cam, Claudia Araya, Claudia A. Escudero, Nibaldo C. Inestrosa, Francisca C. Bronfman, Guojun Bu, and Maria-Paz Marzolo
Common genetic risk of major depression and nicotine dependence: The contribution of antisocial traits in a United States veteran male twin cohort, Qiang Fu, Andrew C. Heath, Kathleen K. Bucholz, Michael J. Lyons, Ming T. Tsuang, William R. true, and Seth A. Eisen
Toxoplasma gondii strains defective in oral transmission are also defective in developmental stage differentiation, Blima Fux, Julie Nawas, Asis Khan, Darcy B. Gill, Chunlei Su, and L David Sibley
Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation, Corinne K. Garofalo, Thomas M. Hooton, Steven M. Martin, Walter E. Stamm, Joseph J. Palermo, Jeffrey I. Gordon, and Scott J. Hultgren
Identification of a novel polyomavirus from patients with acute respiratory tract infections, Anne M. Gaynor, Michael D. Nissen, David M. Whiley, Ian M. Mackay, Stephen B. Lambert, Guang Wu, Daniel C. Brennan, Gregory A. Storch, Theo P. Sloots, and David Wang
Proposed definitions of bipolar I disorder episodes and daily rapid cycling phenomena in preschoolers, school-aged children, adolescents, and adults, Barbara Geller, Rebecca Tillman, and Kristine Bolhofner
NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat, Antonino Germanò, Mariella Caffo, Filippo Flavio Angileri, Francesca Arcadi, Jennifer Newcomb, Gerardo Caruso, Francesco Meli, Jose A. Pineda, Stephen B. Lewis, Kevin K. W. Wang, Placido Bramanti, Chiara Costa, and Ronald L. Hayes
Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse, Emanuele Giurisato, Marina Cella, Toshiyuki Takai, Tomohiro Kurosaki, Yungfeng Feng, Gegory D. Longmore, Marco Colonna, and Andrey S. Shaw
Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency: A case report, Priya K. Gopalan, John C. Clohisy, Amanda F. Cashen, and Charles S. Eby
Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCγ2 signaling axis in mice, Daniel B. Graham, Charles M. Robertson, Jhoanne Bautista, Francesca Mascarenhas, M. Julia Diacovo, Vivianne Montgrain, Siu Kit Lam, Viviana Cremasco, W. Michael Dunne, Roberta Faccio, Craig M. Coopersmith, and Wojciech Swat
An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells, Daniel B. Graham, Linda M. Stephenson, Siu Kit Lam, Karry Brim, Hyang Mi Lee, Jhoanne Bautista, Susan Gilfillan, Shreeram Akilesh, Keiko Fujikawa, and Wojciech Swat
A high-resolution map of segmental DNA copy number variation in the mouse genome, Timothy A. Graubert, Patrick Cahan, Deepa Edwin, Rebecca R. Selzer, Todd A. Richmond, Peggy S. Eis, William D. Shannon, Xia Li, Howard L. McLeod, James M. Cheverud, and Timothy J. Ley
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome, Tina Graves, Robert Fulton, Elaine R. Mardis, Richard K. Wilson, and et al
Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia, Mitchell H. Grayson, Dorothy Cheung, Michelle M. Rohlfing, Robert Kitchens, Daniel E. Spiegel, Jennifer Tucker, John T. Battaile, Yael Alevy, Le Yan, Eugene Agapov, Edy Y. Kim, and Michael J. Holtzman
Calpain activation impairs neuromuscular transmission in a mouse model of the slow-channel myasthenic syndrome, Jason S. Groshong, Melissa J. Spencer, Bula J. Bhattacharyya, Elena Kudryashova, Bhupinder P.S. Vohra, Roberto Zayas, Robert L. Wollmann, Richard J. Miller, and Christopher M. Gomez
Stable preanaphase spindle positioning requires Bud6p and an apparent interaction between the spindle pole bodies and the neck, Brian K. Haarer, Astrid Hoes Helfant, Scott A. Nelson, John A. Cooper, and David C. Amberg
E2F8 is a nonreceptor activator of heterotrimeric G proteins, Ian S. Hagemann, Kirk D. Narzinski, and Thomas J. Baranski
Organogenesis of kidney and endocrine pancreas: The window opens, Marc R. Hammerman
Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D, Kevan L. Hartshorn, Mitchell R. White, Tesfaldet Tecle, Ida Tornoe, Grith L. Sorensen, Erika C. Crouch, and Uffe Holmskov
Large scale gene expression profiles of regenerating inner ear sensory epithelia, R. D. Hawkins, Stavros Bashiardes, Kara E. Powder, Samin A. Sajan, Veena Bhonagiri, David M. Alvarado, Judith Speck, Mark E. Warchol, and Michael Lovett
Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B, Coy D. Heldermon, Anne K. Henning, Kevin K. Ohlemiller, Judith M. Ogilvie, Erik D. Herzog, Annalisa Breidenbach, Carole Vogler, David F. Wozniak, and Mark S. Sands
Comparison of C. elegans and C. briggsae genome sequences reveals extensive conservation of chromosome organization and synteny, LaDeana W. Hiller, Raymond D. Miller, Scott E. Baird, Asif Chinwalla, Lucinda A. Fulton, Daniel C. Koboldt, and Robert H. Waterston
Linkage and association analyses of principal components in expression data, Anthony L. Hinrichs, Robert Culverhouse, Carol H. Jin, and Brian K. Suarez
Haplotyping a quantitative trait with a high-density map in experimental crosses, Wei Hou, John Stephen F. Yap, Song Wu, Tian Liu, James M. Cheverud, and Rongling Wu
The cis-regulatory logic of the mammalian photoreceptor transcriptional network, Timothy H. Hsiau, Claudiu Diaconu, Connie A. Myers, Jongwoo Lee, Constance L. Cepko, and Joseph C. Corbo
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Craig H. Bassing, Tej K. Pandita, and Barry P. Sleckman
Genetic and pharmacological factors that influence reproductive aging in nematodes, Stacie E. Hughes, Kimberley Evason, Chengjie Xiong, and Kerry Kornfeld
Gene duplication of the zebrafish kit ligand and partitioning of melanocyte development functions to kit ligand a, Keith A. Hultman, Nathan Bahary, Leonard I. Zon, and Stephen L. Johnson
The Par-1/MARK family of protein kinases: From polarity to metabolism, Jonathan Hurov and Helen Piwnica-Worms
Changing human visual field organization from early visual to extra-occipital cortex, Anthony I. Jack, Gaurav H. Patel, Serguei V. Astafiev, Abraham Z. Snyder, Erbil Akbudak, Gordon L. Shulman, and Maurizio Corbetta
Genomic and gene regulatory signatures of cryptozoic adaptation: Loss of blue sensitive photoreceptors through expansion of long wavelength-opsin expression in the red flour beetle Tribolium castaneum, Magdalena Jackowska, Riyue Bao, Zhenyi Liu, Elizabeth C. McDonald, Tiffany A. Cook, and Markus Friedrich
Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing, Verena Jantsch, Lois Tang, Pawel Pasierbek, Alexandra Penkner, Sudhir Nayak, Antoine Baudrimont, Tim Schedl, Anton Gartner, and Josef Loidl
Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: Applications in diagnostic imaging and therapy, Hiroyuki Kashiwagi, Jonathan E. McDunn, Peter O. Simon Jr, Peter S. Goedegebuure, Jinbin Xu, Lynne Jones, Katherine Chang, Fabian Johnston, Kathryn Trinkaus, Richard S. Hotchkiss, Robert H. Mach, and William G. Hawkins
Identification and characterization of an RTX toxin in the emerging pathogen Kingella kingae, Thomas E. Kehl-Fie and Joseph W. St. Geme III
Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice, Jennifer Kelly, Aslam Ali Khan, Jiyi Yin, Thomas A. Ferguson, and Rajendra S. Apte
Pancreatitis following Olanzapine Therapy: A Report of Three Cases, Thomas A. Kerr, Sreenivasa Jonnalagadda, Chandra Prakash, and Riad Azar
Cell stress induced by the parkinsonian mimetic, 6-hydroxydopamine, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation, Jeong Sook Kim-Han and Karen L. O'Malley
Rheumatoid arthritis, item response theory, Blom transformation, and mixed models, Aldi T. Kraja, Jon Corbett, An Ping, Rosa S. Lin, Petra A. Jacobsen, Michael Crosswhite, Ingrid B. Borecki, and Michael A. Province
Circumstances of patient falls and injuries in 9 hospitals in a midwestern healthcare system, Melissa J. Krauss, Sheila L. Nguyen, Wm. Claiborne Dunagan, Stanley Birge, Eileen Costantinou, Shirley Johnson, Barbara Caleca, and Victoria J. Fraser
Polyamine permeation and rectification of kir4.1 channels, Yuri V. Kucheryavykh, Wade L. Pearson, Harley T. Kurata, Misty J. Eaton, Serguei N. Skatchkov, and Colin G. Nichols
The role of the cytoplasmic pore in inward rectification of Kir2.1 channels, Harley T. Kurata, Wayland W. Cheng, Christine Arrabit, Paul A. Slesinger, and Colin G. Nichols
Continued use of an integrated meter with electronic logbook maintains improvements in glycemic control beyond a randomized, controlled trial, Lori M. B. Laffel, William C. Hsu, Janet B. McGill, Luigi Meneghini, and Lisa K. Volkening
The bandit, a new DNA transposon from a hookworm— possible horizontal genetic transfer between host and parasite, Thewarach Laha, Alex Loukas, Supatra Wattanasatitarpa, Jenjira Somprakhon, Nonglack Kewgrai, Paiboon Sithithaworn, Sasithorn Kaewkes, Makedonka Mitreva, and Paul J. Brindley
Targeted discovery of novel human exons by comparative genomics, Laura Langton, Michael Stevens, Charles L.G. Comstock, Michael R. Brent, and et al
The 14-3-3τ phosphoserine-binding protein is required for cardiomyocyte survival, Jeffrey M. C. Lau, Xiaohua Jin, Jie Ren, Joan Avery, Brian J. DeBosch, Ilya Treskov, Traian S. Lupu, Attila Kovacs, Carla Weinheimer, and Anthony J. Muslin
Yersiniabactin is a virulence factor for Klebsiella pneumoniae during pulmonary infection, Matthew S. Lawlor, Christopher O'Connor, and Virginia L. Miller
Clostridium difficile in the intensive care unit: Epidemiology, costs, and colonization pressure, Steven J. Lawrence, Laura A. Puzniak, Brooke N. Shadel, Kathleen N. Gillespie, Marin H. Kollef, and Linda M. Mundy
Comparative analysis of the regulation of rovA from the pathogenic Yersiniae, Matthew B. Lawrenz and Virginia L. Miller
Evaluation of a novel chromogenic agar medium for isolation and differentiation of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis isolates, Nathan A. Ledeboer, Kingshuk Das, Michael Eveland, Celine Roger-Dalbert, Sandrine Mailler, Sonia Chatellier, and William Michael Dunne
Prevalence of cervical spine stenosis: Anatomic study in cadavers, Michael J. Lee, Ezequiel H. Cassinelli, and K. Daniel Riew
A little stress is good: IFN-γ, demyelination, and multiple sclerosis, Jason R. Lees and Anne H. Cross
Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli, Yvonne M. Lee, Karen W. Dodson, and Scott J. Hultgren
Management of juvenile idiopathic scoliosis, Lawrence G. Lenke and Matthew B. Dobbs
Calmodulin kinase II inhibition enhances ischemic preconditioning by augmenting ATP-sensitive K+ current, Jingdong Li, Celine Marionneau, Olha Koval, Leonid Zingman, Peter J. Mohler, Jeanne M. Nerbonne, and Mark E. Anderson
PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancer, W. T. Lim, W. H. Zhang, C. R. Miller, J. W. Watters, F. Gao, A. Viswanathan, R Govindan, and H. L. McLeod
Vascular injury from an arterial closure device, Jeffrey P. C. Lin, Brian G. Rubin, and William D. Middleton
Large-scale in silico mapping of complex quantitative traits in inbred mice, Pengyuan Liu, Haris Vikis, Yan Lu, Daolong Wang, and Ming You
Functional association of Sun1 with nuclear pore complexes, Qian Liu, Nelly Pante, Tom Misteli, Mohamed Elsagga, Melissa Crisp, Didier Hodzic, Brian Burke, and Kyle J. Roux
Acrochordon-like basal cell carcinomas in patients with basal cell nevus syndrome, David N. Lortscher, Roberta D. Sengelmann, and Shawn B. Allen
Contribution of invariant residues to the function of Rgg family transcription regulators, Jennifer Loughman and Michael G. Caparon
Diffusion tensor imaging predicts hyperacute spinal cord injury severity, David N. Loy, Joong Hee Kim, Mingqiang Xie, Robert E. Schmidt, Kathryn Trinkaus, and Sheng-Kwei Song
Psychotropic prescriptions in a sample including both healthy and mood and disruptive disordered preschoolers: relationships to diagnosis, impairment, prescriber type, and assessment methods, Joan L. Luby, Melissa Meade Stalets, and Andy C. Belden
Three clinical cases of DSM-IV mania symptoms in preschoolers, Joan Luby, Mini Tandon, and Ginger Nicol
Ivermectin resistance in Onchocerca volvulus: Toward a genetic basis, Sara Lustigman and James P. McCarter
Common human cancer genes discovered by integrated gene-expression analysis, Yan Lu, Yijun Yi, Pengyuan Liu, Weidong Wen, Michael James, Daolong Wang, and Ming You
