The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2006

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YtxR, a conserved LysR-like regulator that induces expression of genes encoding a putative ADP-ribosyltransferase toxin homologue in Yersinia enterocolitica, Grace L. Axler-DiPerte, Virginia L. Miller, and Andrew J. Darwin

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Is influenza an influenza-like illness? Clinical presentation of influenza in hospitalized patients, Hilary M. Babcock, Liana R. Merz, and Victoria J. Fraser

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Fast cloning inverted repeats for RNA interference, Sujin Bao and Ross L. Cagan

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Direct observation of a preinactivated, open state in BK channels with β2 subunits, G. Richard Benzinger, Xiao-Ming Xia, and Christopher J. Lingle

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Recent advances in basic neurosciences and brain disease: From synapses to behavior, Guo-Qiang Bi, Vadim Bolshakov, Guojun Bu, Catherine M. Cahill, Zhou-Feng Chen, Graham L. Collingridge, Robin L. Cooper, Jens R. Coorssen, Alaa El-Husseini, Vasco Galhardo, Web-Biao Gan, Jianguo Gu, Kazuhide Inoue, John Isaac, Koichi Iwata, Zhengping Jia, Bong-Kiun Kaang, Mikito Kawamata, Satoshi Kida, Eric Klann, Tatsuro Kohno, Min Li, Xiao-Jiang Li, John F. MacDonald, Karim Nader, Peter V. Nguyen, Uhtaek Oh, Ke Ren, John C. Roder, Michael W. Salter, Weihong Song, Shuzo Sugita, Shao-Jun Tang, Yuanxiang Tao, Yu Tian Wang, Newton Woo, Melanie A. Woodin, Zhen Yan, Megumu Yoshimura, Ming Xu, Zao C. Xu, Xia Zhang, Mei Zhen, and Min Zhuo

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Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes, Kumar S. Bishnupuri, Qizhi Luo, Joshua R. Korzenik, Jeffrey O. Henderson, Courtney W. Houchen, Shrikant Anant, and Brian K. Dieckgraefe

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Effect of exercise training on in vitro LDL oxidation and free radical-induced hemolysis: The HERITAGE family study, Denis Blache, Suzanne Lussier-Cacan, Jacques Gagnon, Arthur S. Leon, D.C. Rao, James S. Skinner, Jack H. Wilmore, Tuomo Rankinen, Claude Bouchard, and Jean Davignon

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Long-term memory deficits in Pavlovian fear conditioning in Ca2+/calmodulin kinase kinase α-deficient mice, Frank Blaeser, Matthew J. Sanders, Nga Truong, Shanelle Ko, Long Jun Wu, David F. Wozniak, Michael S. Fanselow, Min Zhuo, and Talal A. Chatila

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Pancreatic regenerating protein (regⅠ) and regⅠreceptor mRNA are upregulated in rat pancreas after induction of acute pancreatitis, Martin H. Bluth, Sameer A. Patel, Brian K. Dieckgraefe, Hiroshi Okamoto, and Michael E. Zenilman

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A critical role for eukaryotic elongation factor 1A-1 in lipotoxic cell death, Nica M. Borradaile, Kimberly K. Buhman, Laura L. Listenberger, Carolyn J. Magee, Emiko T.A. Morimoto, Daniel S. Ory, and Jean E. Schaffer

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Correlates of physical activity for adults with disability, Sarah E. Boslaugh and Elena M. Andresen

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Effective control of chronic c-herpesvirus infection by unconventional MHC class Ia–independent CD8 T cells, Douglas C. Braaten, James Scott McClellan, Ilhem Messaoudi, Scott A. Tibbetts, Kelly B. McClellan, Janko Nikolich-Zugich, and Herber W. Virgin IV

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang

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Symposium: Subspecialty certification: Current status of orthopaedic subspecialty certification, Keith H. Bridwell, Christopher D. Harner, David W. Polly Jr., and Peter J. Stern

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Genetic architecture of smoking behavior: A study of Finnish adult twins, Ulla Broms, Karri Silventoinen, Pamela A.F. Madden, Andrew C. Heath, and Jaakko Kaprio

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A glucose sensor in Candida albicans, Victoria Brown, Jessica A. Sexton, and Mark Johnston

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Zoom in on neurodegeneration, Guojun Bu, Huaxi Xu, and Todd E. Golde

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Use of an Ilizarov apparatus to perform closed reduction of a chronic proximal dislocation following total hip arthroplasty: A case report, R. Allen Butler, Joseph R. Hsu, and Robert L. Barrack

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Modulation of β-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family, Judy A. Cam and Guojun Bu

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Does HIV cause cardiovascular disease?, Andrew Carr and Daniel Ory

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A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles, Li-Wei Chang, Rakesh Nagarajan, Jeffrey A. Magee, Jeffrey Milbrandt, and Gary D. Stormo

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Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: A possible mechanism for the analgesic effect of L-acetylcarnitine, Santina Chiechio, Agata Copani, Laura De Petris, Maria Elena P. Morales, Ferdinando Nicoletti, and Robert W. Gereau IV

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Characterization of multimeric complexes formed by the human PTB1 protein on RNA, Caroline Clerte and Kathleen B. Hall

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Toll-like receptors and IFN-α: Partners in autoimmunity, Marco Colonna

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Trimeric autotransporters require trimerization of the passenger domain for stability and adhesive activity, Shane E. Cotter, Neeraj K. Surana, Susan Grass, and Joseph W. St. Geme III

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Mechanisms of sympathoadrenal failure and hypoglycemia in diabetes, Philip E. Cryer

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Contraselectable streptomycin susceptibility determinant for genetic manipulation and analysis of Helicobacter pylori, Daiva Dailidiene, Giedrius Dailide, Dangeruta Kersulyte, and Douglas E. Berg

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Adaptively inferring human transcriptional subnetworks, Debopriya Das, Zaher Nahlé, and Michael Q. Zhang

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VPg of murine norovirus binds translation initiation factors in infected cells, Katie F. Daughenbaugh, Christiane E. Wobus, and Michele E. Hardy

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Maintenance of warfarin anticoagulation for patients undergoing vitreoretinal surgery, Pouya N. Dayani and M. Gilbert Grand

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New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases, Franck Dequiedt, Maud Martin, Julia Von Blume, Didier Vertommen, Emily Lecomte, Nathalie Mari, Marie-France Heinen, Malte Bachmann, Jean-Claude Twizere, Mei Chris Huang, Mark H. Rider, Helen Piwnica-Worms, Thomas Seufferlein, and Richard Kettmann

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The type and frequency of fetal renal disorders and management of renal pelvis dilatation, Jeffrey M. Dicke, Valerie M. Blanco, Yan Yan, and Douglas E. Coplen

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Long-term follow-up of patients with clubfeet treated with extensive soft-tissue release, Matthew B. Dobbs, Ryan Nunley, and Perry L. Schoenecker

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Early results of a new method of treatment for idiopathic congenital vertical talus, Matthew B. Dobbs, Derek B. Purcell, Ryan Nunley, and Jose A. Morcuende

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GOurmet: A tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributions, Jason M. Doherty, Lynn K. Carmichael, and Jason C. Mills

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Efficient pairwise RNA structure prediction and alignment using sequence alignment constraints, Robin D. Dowell and Sean R. Eddy

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Relationships between upper-limb functional limitation and self-reported disability 3 months after stroke, Alexander W. Dromerick, Catherine E. Lang, Rebecca Birkenmeier, Michele G. Hahn, Shirley A. Sahrmann, and Dorothy F. Edwards

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H-NS represses inv transcription in Yersinia enterocolitica through competition with RovA and interaction with YmoA, Damon W. Ellison and Virginia L. Miller

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Outbreak of Salmonella javiana infection at a children's hospital, Alexis Elward, Autumn Grim, Patricia Schroeder, Patricia Kieffer, Patricia Sellenriek, Rhonda Ferrett, Hilda Chaski Adams, Virginia Phillips, Rhonda Bartow, Debra Mays, Steven Lawrence, Patrick Seed, Galit Holzmann-Pazgal, Louis Polish, Terry Leet, and Victoria Fraser

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Risk factors for nosocomial primary bloodstream infection in pediatric intensive care unit patients: A 2-year prospective cohort study, Alexis M. Elward and Victoria J. Fraser

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Surfactant protein D increases fusion of Mycobacterium tuberculosis- containing phagosomes with lysosomes in human macrophages, J Scott Ferguson, Jennifer L. Martin, Abul K. Azad, Travis R. McCarthy, Peter B. Kang, Dennis R. Voelker, Erika C. Crouch, and Larry S. Schlesinger

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PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease, Brian N. Finck and Daniel P. Kelly

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Effectiveness of enterobacterial repetitive intergenic consensus PCR and random amplified polymorphic DNA fingerprinting for Helicobacter pylori strain differentiation, S. Alison Finger, Billie Velapatino, Margaret Kosek, Livia Santivanez, Daiva Dailidiene, Willi Quino, Jacqueline Balqui, Phabiola Herrera, Douglas E. Berg, and Robert H. Gilman

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Computational hyperspectral interferometry for studies of brain function: Proof of concept, Douglas J. Fox, Hana T. Velde, Chrysanthe Preza, Joseph A. O'Sullivan, William H. Smith, and Thomas A. Woolsey

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Nicotine delays tendon-to-bone healing in a rat shoulder model, L. M. Galatz, M. J. Silva, S. Y. Rothermich, M. A. Zaegel, N. Havlioglu, and S. Thomopoulos

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Nipped-A, the Tra1/TRRAP subunit of the Drosophila SAGA and Tip60 complexes, has multiple roles in Notch signaling during wing development, Maria Gause, Joel C. Eissenberg, Any F. MacRae, Maia Dorsett, Ziva Misulovin, and Dale Dorsett

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Phylogeny based discovery of regulatory elements, Jason Gertz, Justin C. Fay, and Barak A. Cohen

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Volumetric measurements of lung nodules with multi-detector row CT: Effect of changes in lung volume, Jin Mo Goo, Kwang Gi Kim, David S. Gierada, Mario Castro, and Kyongtae T. Bae

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Femoral deformity in tibia vara, J. Eric Gordon, David J. King, Scott J. Luhmann, Matthew B. Dobbs, and Perry L. Schoenecker

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A phase I trial of docetaxel and vinorelbine in patients with advanced non-small cell lung cancer, Ramaswamy Govindan, Wan-Teck Lim, Matthew A. Arquette, Sherry A. Goodner, Carole L. Fears, Joanne E. Mortimer, and Paula M. Fracasso

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Current concepts review: Management of elbow osteoarthritis, Gregory D. Gramstad and Leesa M. Galatz

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Chemokine signaling regulates apoptosis as well as immune cell traffic in host defense, Mitchell H. Grayson and Michael J. Holtzman

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Genetic variation in the zebrafish, Victor Guryev, Marco J. Koudijs, Eugene Berezikov, Stephen L. Johnson, Ronald H.A. Plasterk, Fredericus J.M. Van Eeden, and Edwin Cuppen

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Harnessing preclinical mouse models to inform human clinical cancer trials, David H. Gutmann, Kim Hunter-Schaedle, and Kevin M. Shannon

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Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: Results from CALGB 9342, Lyndsay N. Harris, Gloria Broadwater, Nancy U. Lin, Alexander Miron, Stuart J. Schnitt, David Cowan, Jonathan Lara, Ira Bleiweiss, Donald Berry, Matthew Ellis, Daniel F. Hayes, Eric P. Winer, and Lynn Dressler

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Mechanistic insights into the regulation of the spermatogonial stem cell niche, Rex A. Hess, Paul S. Cooke, Marie-Claude Hofmann, and Kenneth M. Murphy

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Lysosomal phospholipase A2 and phospholipidosis, Miki Hiraoka, Akira Abe, Ye Lu, Kui Yang, Xianlin Han, Richard Gross, and James A. Shayman

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Elastin fragments drive disease progression in a murine model of emphysema, A. McGarry Houghton, Pablo A. Quintero, David L. Perkins, Dale K. Kobayashi, Diane G. Kelley, Luiz A. Marconcini, Robert P. Mecham, Robert M. Senior, and Steven D. Shapiro

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Application of a superword array in genome assembly, Xiaoqiu Huang, Shiaw-Pyng Yang, Asif T. Chinwalla, LaDeana W. Hillier, Patrick Minx, Elaine R. Mardis, and Richard K. Wilson

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Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin, Tobias B. Huber, Christopher Kwoh, Hui Wu, Katsuhiko Asanuma, Markus Gödel, Björn Hartleben, Ken J. Blumer, Jeffrey H. Miner, Peter Mundel, and Andrey S. Shaw

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Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis, Sonja G. Hunter, Guanglei Zhuang, Dana Brantley-Sieders, Wojciech Swat, Christopher W. Cowan, and Jin Chen

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The molecular portraits of breast tumors are conserved across microarray platforms, Zhiyuan Hu, Cheng Fan, Daniel S. Oh, J S. Marron, Xiaping He, Bahjat F. Qaqish, Chad Livasy, Lisa A. Carey, Evangeline Reynolds, Lynn Dressler, Andrew Nobel, Joel Parker, Matthew G. Ewend, Lynda R. Sawyer, Junyuan Wu, Yudong Liu, Rita Nanda, Maria Tretiakova, Alejandra Ruiz Orrico, Donna Dreher, Juan P. Palazzo, Laurent Perreard, Edward Nelson, Mary Mone, Heidi Hansen, Michael Mullins, John F. Quackenbush, Matthew J. Ellis, Olufunmilayo I. Olopade, Philip S. Bernard, and Charles M. Perou

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ShiA abrogates the innate T-cell response to Shigella flexneri infection, Molly A. Ingersoll and Arturo Zychlinsky

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Pigment pattern in jaguar/obelix zebrafish is caused by a Kir7.1 mutation: Implications for the regulation of melanosome movement, Motoko Iwashita, Masakatsu Watanabe, Masaru Ishii, Tim Chen, Stephen L. Johnson, Yoshihisa Kurachi, Norihiro Okada, and Shigeru Kondo

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Proteinuria precedes podocyte abnormalities in Lamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier, George Jarad, Jeanette Cunningham, Andrey S. Shaw, and Jeffrey H. Miner

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Human sensory-evoked responses differ coincident with either "fusion-memory" or "flash-memory", as shown by stimulus repetition-rate effects, Don L. Jewett, Toryalai Hart, Linda J. Larson-Prior, Bill Baird, Marram Olson, Michael Trumpis, Katherine Makayed, and Payam Bavafa

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A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients, Peter R. Joyce, Patrick C. McHugh, Janice M. McKenzie, Patrick F. Sullivan, Roger T. Mulder, Suzanne E. Luty, Janet D. Carter, Christopher M. Frampton, and C. R. Cloninger

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Maturation of intracellular Escherichia coli communities requires SurA, Sheryl S. Justice, Scott R. Lauer, Scott J. Hultgren, and David A. Hunstad

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Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification, Sharon L.R. Kardia, Lawrence F. Bielak, Leslie A. Lange, James M. Cheverud, Eric Boerwinkle, Stephen T. Turner, Patrick F. Sheedy II, and Patricia A. Peyser

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Impaired inflammatory pain and thermal hyperalgesia in mice expressing neuron-specific dominant negative mitogen activated protein kinase kinase (MEK), Farzana Karim, Hui-Juan Hu, Hita Adwanikar, David Kaplan, and Robert W. Gereau IV

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Immunization with persistent attenuated Δlpg2 Leishmania major parasites requires adjuvant to provide protective immunity in C57BL/6 mice, Chahnaz Kebaier, Jude E. Uzonna, Stephen M. Beverley, and Phillip Scott

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A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors, Peter A. Keyel, Sanjay K. Mishra, Robyn Roth, John E. Heuser, Simon C. Watkins, and Linton M. Traub

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Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii, Asis Khan, L. David Sibley, and et al

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Dual infection with Mycobacterium tuberculosis and Pneumocystis jiroveci lymphadenitis in a patient with HIV infection: case report and review of the literature, Thana Khawcharoenporn, Anucha Apisarnthanarak, Dussadee Sakonlaya, Linda M. Mundy, and Thomas C. Bailey

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Proteasome activator PA200 is required for normal spermatogenesis, Bernard Khor, Andrea L. Bredemeyer, Ching-Yu Huang, Isaiah R. Turnbull, Ryan Evans, Leonard B. Maggi Jr., J. Michael White, Laura M. Walker, Kay Carnes, Rex A. Hess, and Barry P. Sleckman

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Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway, Dong-Jo Kim, Jun-Ho Chung, Eun-Kyeong Ryu, Jung-Hyo Rhim, Yoon-Sic Ryu, So-Hyun Park, Kyung Tae Kim, Heun-Soo Kang, Hong-Keun Chung, and Sang Chul Park

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Glucocorticoids suppress bone formation via the osteoclast, Hyun-Ju Kim, Haibo Zhao, Hideki Kitaura, Sandip Bhattacharyya, Judson A. Brewer, Louis J. Muglia, Patrick Ross, and Steven L. Teitelbaum

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Integration of transcriptional and posttranslational regulation in a glucose signal transduction pathway in Saccharomyces cerevisiae, Jeong-Ho Kim, Valerie Brachet, Hisao Moriya, and Mark Johnston

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Actin-based motility during endocytosis in budding yeast, Kyoungtae Kim, Brian J. Galletta, Kevin O. Schmidt, Fanny S. Chang, Kendall J. Blumer, and John A. Cooper

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Maternal alcohol use disorder and offspring ADHD: Disentangling genetic and environmental effects using a children-of-twins design, Valerie S. Knopik, Andrew C. Heath, Theodore Jacob, Wendy S. Slutske, Kathleen K. Bucholz, Pamela A F Madden, Mary Waldron, and Nicholas G. Martin

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The intensive care unit as a research laboratory: Developing strategies to prevent antimicrobial resistance, Marin H. Kollef

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The molecular scaffold kinase suppressor of Ras 1 is a modifier of Ras(V12)-induced and replicative senescence, Robert L. Kortum, Heidi J. Johnson, Diane L. Costanzo, Deanna J. Volle, Gina L. Razidlo, Angela M. Fusello, Andrey S. Shaw, and Robert E. Lewis

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The polyamine binding site in inward rectifier K+ channels, Harley T. Kurata, Laurence J. Marton, and Colin G. Nichols

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Comparison of the host responses to wild-type and cpsB mutant Klebsiella pneumoniae infections, Matthew S. Lawlor, Scott A. Handley, and Virginia L. Miller

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RNA in situ hybridization of dissected gonads, Min-Ho Lee and Tim Schedl

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RNA-binding proteins, Min'Ho Lee and Tim Schedl

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Quantitative effect of luxS gene inactivation on the fitness of Helicobacter pylori, Won-Kon Lee, Keiji Ogura, John T. Loh, Timothy L. Cover, and Douglas E. Berg

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Effect of lung surfactant collectins on bronchoalveolar macrophage interaction with Blastomyces dermatitidis: Inhibition of tumor necrosis factor alpha production by surfactant protein D, Madhavi Lekkala, Ann Marie LeVine, Michael J. Linke, Erika C. Crouch, Bruce Linders, Elmer Brummer, and David A. Stevens

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Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit, Van Leung-Pineda, Christine E. Ryan, and Helen Piwnica-Worms

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Unexpected diversity and complexity of the Guerrero Negro hypersaline microbial mat, Ruth Ley, J. Kirk Harris, Joshua Wilcox, John R. Spear, Scott R. Miller, Brad M. Bebout, Julia A. Maresca, Donald A. Bryant, Mitchell L. Sogin, and Norman R. Pace

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Blinded comparison of repetitive-sequence PCR and multilocus sequence typing for genotyping methicillin-resistant Staphylococcus aureus isolates from a children's hospital in St. Louis, Missouri, Robert S. Liao, Gregory A. Storch, Richard S. Buller, Rachel C. Orscheln, Elaine R. Mardis, Jon R. Armstrong, and W. Michael Dunne Jr.

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Enhanced analgesia with opioid antagonist administration, Jane E. Loitman

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A unique role for Stat5 in recovery from acute anemia, Gregory D. Longmore

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Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a model for in vivo gene expression, Jennifer A. Loughman and Michael Caparon

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Effect of conventional and organic production practices on the prevalence and antimicrobial resistance of Campylobacter spp. in poultry, Taradon Luangtongkum, Teresa Y. Morishita, Aaron J. Ison, Shouxiong Huang, Patrick F. McDermott, and Qijing Zhang

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Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy, Joan Luby, Christine Mrakotsky, Melissa Meade Stalets, Andy Belden, Amy Heffelfinger, Meghan Williams, and Edward Spitznagel

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A gene expression signature predicts survival of patients with stage I non-small cell lung cancer, Yan Lu, William Lemon, Peng-Yuan Liu, Yigun Yi, Carl Morrison, Ping Yang, Zhifu Sun, Janos Szoke, William L. Gerald, Mark Watson, Ramaswamy Govindan, and Ming You

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Cold shock domain family members YB-1 and MSY4 share essential functions during murine embryogenesis, Zhi Hong Lu, Jason T. Books, and Timothy J. Ley

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Subtypes of illicit drug users: A latent class analysis of data from an Australian twin sample, Michael T. Lynskey, Arpana Agrawal, Kathleen K. Bucholz, Elliot C. Nelson, Pamela A.F. Madden, Alexandre A. Todorov, Julia D. Grant, Nicholas G. Martin, and Andrew C. Heath

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An improved map of conserved regulatory sites for Saccharomyces cerevisiae, Kenzie D. MacIsaac, Ting Wang, D Benjamin Gordon, David K. Gifford, Gary D. Stormo, and Ernest Fraenkel