The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2016

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Programmatic use of molecular xenomonitoring at the level of evaluation units to assess persistence of lymphatic filariasis in Sri Lanka, Ramakrishna U. Rao, Sandhya D. Samarasekera, Kumara C. Nagodavithana, Manjula W. Punchihewa, Tharanga D. M. Dassanayaka, Gamini P. K. D, Ethan Ford, Udaya S. B. Ranasinghe, Ralph H. Henderson, and Gary J. Weil

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A framework for interpreting type I error rates from a product-term model of interaction applied to quantitative traits, Tara J. Rao and Michael A. Province

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Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development, David Razafsky, Candace Ward, Chloe Potter, Wanqiu Zhu, Yunlu Xue, Vladimir J. Kefalov, Loren G. Fong, Stephen G. Young, and Didier Hodzic

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Clec16a is critical for autolysosome function and Purkinje cell survival, Veronika Redmann, Robert C. Orchard, Ashley Milam, Sunmin Park, Christine C. Yokoyama, Amal Kambal, Darren Kreamalmeyer, Karen Green, Paul M. Allen, Robert E. Schmidt, Herbert W. Virgin, Marie K. Bosch, Maolei Xiao, David M. Ornitz, Aaron DiAntonio, Shondra M. Pruett-Miller, Sungsu Kim, Wanda L. Beatty, and et al

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Atorvastatin improves ventricular remodeling after myocardial infarction by interfering with collagen metabolism, Karla Reichert, Helison Rafael Pereira do Carmo, Anali Galluce Torina, Daniela Diogenes de Carvalho, Andrei Carvalho Sposito, Karlos Alexandre de Souza Vilarinho, Lindemberg de Mota Silveira-Filho, Pedro Paulo Martins de Oliveira, and Orlando Petrucci

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Predictors of change in depressive symptoms from preschool to first grade, Trude Reinfjell, Silja Berg Kårstad, Turid Suzanne Berg-Nielsen, Joan L. Luby, and Lars Wichstrøm

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Computational neurorehabilitation: Modeling plasticity and learning to predict recovery, David J. Reinkensmeyer, Etienne Burdet, Maura Casadio, John W. Krakauer, Gert Kwakkel, Catherine E. Lang, Stephan P. Swinnen, Nick S. Ward, and Nicolas Schweighofer

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Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells, Matthew R. Reynolds, Itender Singh, Tej D. Azad, Brandon B. Holmes, Phillip B. Verghese, Hans H. Dietrich, Marc Diamond, Guojun Bu, Byung Hee Han, and Gregory J. Zipfel

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Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation, Adam D. Richardson, David A. Scott, Olga Zagnitko, Pedro Aza-Blanc, Chih-Cheng Chang, and David A. Russler-Germain

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What are effective program characteristics of self-management interventions in patients with heart failure? An individual patient data meta-analysis, Michael W. Rich and et al

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Challenges in drug discovery for neurofibromatosis type 1-associated low-grade glioma, Cora A. Ricker, Yuan Pan, David H. Gutmann, and Charles Keller

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Analysis of within subjects variability in mouse ultrasonic vocalization: Pups exhibit inconsistent, state-like patterns of call production, Michael A. Rieger and Joseph D. Dougherty

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ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β, Agnieszka Robaszkiewicz, Chao Qu, Ewelina Wisnik, Tomasz Ploszaj, Ali Mirsaidi, Friedrich A. Kunze, Peter J. Richards, Paolo Cinelli, Gabriel Mbalaviele, and Michael O. Hottiger

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Implementation of a screening program for patients at risk for posttraumatic stress disorder, Carmen R. Roberts, Joanie E. Wofford, Haley M. Hoy, and Mitchell N. Faddis

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Synthetic ligands of cannabinoid receptors affect dauer formation in the nematode Caenorhabditis elegans, Pedro Reis Rodrigues, Tiffany K. Kaul, Jo-Hao Ho, Mark Lucanic, Kristopher Burkewitz, William B. Mair, Jason M. Held, Laura M. Bohn, and Matthew S. Gill

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ISG15 deficiency and increased viral resistance in humans but not mice, Marisela R. Rodriguez, Deborah J. Lenschow, and et al

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Safety of two-year caloric restriction in non-obese healthy individuals, Sergei V. Romashkan, Sai Krupa Das, Dennis T. Villareal, Eric Ravussin, Leanne M. Redman, James Rochon, Manjushri Bhapkar, and William E. Kraus

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L-MYC expression maintains self-renewal and prolongs multipotency of primary human neural stem cells, Xianfang Rong, Joseph Benetatos, David L. Brody, and et al

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Stroke severity Is a crucial predictor of outcome: An international prospective validation study, Natalia S. Rost, Alex Bottle, Jin-Moo Lee, Marc Randall, Steven Middleton, Louise Shaw, Vincent Thijs, Gabriel J.E. Rinkel, Thomas M. Hemmen, and Global Comparators Stroke GOAL collaborators

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Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis, Megan K. Ruhland, Andrew J. Loza, Aude-Helene Capietto, Xianmin Luo, Brett L. Knolhoff, Kevin C. Flanagan, Brian A. Belt, Elise Alspach, Kathleen Leahy, Jingqin Luo, Andras Schaffer, John R. Edwards, Gregory Longmore, Roberta Faccio, David G. DeNardo, and Sheila A. Stewart

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Whole genome sequencing for genomics-guided investigations of Escherichia coli O157:H7 outbreaks, Brigida Rusconi, Fatemeh Sanjar, Sara S.K. Koenig, Mark K. Mammel, Phillip I. Tarr, and Mark Eppinger

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Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma, Scott Ryall, Rahul Krishnatry, Anthony Arnoldo, Pawel Buczkowicz, Matthew Mistry, Robert Siddaway, Cino Ling, Sanja Pajovic, Man Yu, Joshua B. Rubin, Juliette Hukin, Paul Steinbok, Ute Bartels, Eric Bouffet, Uri Tabori, and Cynthia Hawkins

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Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations, Jessica L. Saben, Anna L. Boudoures, Zeenat Asghar, Alysha Thompson, Andrea Drury, Wendy Zhang, Maggie Chi, Andrew Cusumano, Suzanne Scheaffer, and Kelle H. Moley

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Short-term treatment outcomes in human immunodeficiency virus type-1 and hepatitis B virus co-infections, Kwamena William Coleman Sagoe, Kwabena Obeng Duedu, Francesca Ziga, Afrakoma Adjoa Agyei, Theophilus Korku Adiku, Margaret Lartey, Julius Abraham Addo MIngle, and Max Arens

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The Na+/Ca2+, K+ exchanger 2 modulates mammalian cone phototransduction, Keisuke Sakurai, Frans Vinberg, Tian Wang, Jeannie Chen, and Vladimir J. Kefalov

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Reducing CSF partial volume effects to enhance diffusion tensor imaging metrics of brain microstructure, Lauren E. Salminen, Thomas E. Conturo, Jacob D. Bolzenius, Ryan P. Cabeen, Erbil Akbudak, and Robert H. Paul

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Reversible intraoperative neurophysiologic monitoring alerts in patients undergoing arthrodesis for adolescent idiopathic scoliosis, Amer F. Samdani, James T. Bennett, Robert J. Ames, Jahangir K. Asghar, Giuseppe Orlando, Joshua M. Pahys, Burt Yaszay, Firoz Miyanji, Baron S. Lonner, Ronald A. Lehman Jr, Peter O. Newton, Patrick J. Cahill, and Randal R. Betz

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Gene regulatory networks in neural cell fate acquisition from genome-wide chromatin association of Geminin and Zic1, Savita Sankar, Dhananjay Yellajoshyula, Bo Zhang, Bryan Teets, Nicole Rockweiler, and Kristen L. Kroll

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Epidemiology of bloodstream infections in a multicenter retrospective cohort of liver transplant recipients, Carlos A.Q. Santos, Richard S. Hotchkiss, William C. Chapman, and Margaret A. Olsen

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NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion, Yo Sasaki, Takashi Nakagawa, Xianrong Mao, Aaron DiAntonio, and Jeffrey Milbrandt

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The dimeric architecture of checkpoint kinases Mec1ATR and Tel1ATM reveal a common structural organization, Marta Sawicka, Paulina H. Wanrooij, Vidya C. Darbari, Elias Tannous, Sarem Hailemariam, Daniel Bose, Alena V. Makarova, Peter M. Burgers, and Xiaodong Zhang

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The dimeric architecture of checkpoint Mec1ATR and Tel1ATM reveal a common structural organization, Marta Sawicka, Paulina H. Wanrooij, Vidya C. Darbari, Elias Tannous, Sarem Hailemariam, Daniel Bose, Alena V. Makarova, Peter M. Burgers, and Xiaodong Zhang

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A proteinaceous organic matrix regulates carbonate mineral production in the marine teleost intestine, Kevin L. Schauer, Christophe M. R. LeMoine, Adrian Pelin, Nicolas Corradi, Wesley C. Warren, and Martin Grosell

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Changes in skeletal integrity and marrow adiposity during high-fat diet and after weight loss, Erica L. Scheller, Basma Khoury, Kayla L. Moller, Natalie K.Y. Wee, Shaima Khandaker, Kenneth M. Kozloff, Simin H. Abrishami, Brian F. Zamarron, and Kanakadurga Singer

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Disruption of the Cdc42/Par6/aPKC or Dlg/ Scrib/Lgl polarity complex promotes epithelial proliferation via overlapping mechanisms, Gregory V. Schimizzi, Meghan T. Maher, Andrew J. Loza, and Gregory D. Longmore

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AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity, Edward T. Schmid, Iris K. Pang, Eugenio A. Carrera Silva, Lidia Bosurgi, Jonathan J. Miner, Michael S. Diamond, Akiko Iwasaki, and Carla V. Rothlin

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A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection, Diane J. Schmidt, Gillian Beamer, Jacqueline M. Tremblay, Jennifer A. Steele, Hyeun Bum Kim, Yaunkai Wang, Michele Debatis, Xingmin Sun, Elena A. Kashentseva, Igor P. Dmitriev, David T. Curiel, Charles B. Shoemaker, and Saul Tzipori

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A compendium of chromatin contact maps reveals spatially active regions in the human genome, Anthony D. Schmitt, Ming Hu, Inkyung Jung, Zheng Xu, Yunjiang Qiu, Catherine L. Tan, Yun Li, Shin Lin, Yiing Lin, Cathy L. Barr, and Bing Ren

Genome sequence of the basal haplorrhine primate Tarsius syrichta reveals unusual insertions, Jürgen Schmitz, Angela Noll, Carsten A. Raabe, Gennady Churakov, Reinhard Voss, Martin Kiefmann, Timofey Rozhdestvensky, Jürgen Brosius, Robert Baertsch, Hiram Clawson, Christian Roos, Aleksey Zimin, Patrick Minx, Michael J. Montague, Richard K. Wilson, and Wesley C. Warren

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Emerging technologies to measure neighborhood conditions in public health: Implications for interventions and next steps, M. Schootman, E. J. Nelson, K. Werner, E. Shacham, M. Elliott, K. Ratnapradipa, M. Lian, and A. McVay

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Child stunting is associated with low circulating essential amino acids, Richard D. Semba, Michelle Shardell, Fayrouz A. Sakr Ashour, Ruin Moaddel, Indi Trehan, Kenneth M. Maleta, M. Isabel Ordiz, Klaus Kraemer, Mohammed A. Khadeer, Luigi Ferrucci, and Mark J. Manary

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Metabolic alterations in children with environmental enteric dysfunction, Richard D. Semba, Michelle Shardell, Indi Trehan, Ruin Moaddel, Kenneth M. Maleta, M. Isabel Ordiz, Klaus Kraemer, Mohammed Khadeer, Luigi Ferrucci, and Mark J. Manary

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Sustained reduction of diversion and abuse after introduction of an abuse deterrent formulation of extended release oxycodone, Stevan Geoffrey Severston, Matthew S. Ellis, Stephen P. Kurtz, Andrew Rosenblum, Theodore J. Cicero, Mark W. Parrino, Michael K. Gilbert, Mance E. Buttram, Nabarun Dasgupta, Becki BucherBartelson, Jody L. Green, and Richard C. Dart

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Using free internet videogames in upper extremity motor training for children with cerebral palsy, Marisa Sevick, Elizabeth Eklund, Allison Mensch, Matthew Foreman, John Standeven, and Jack Engsberg

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Cost-effective recruitment strategies that attract underrepresented minority undergraduates who persist to STEM doctorates, Cherilynn R. Shadding, Dawayne Whittington, Latricia E. Wallace, Wambul S. Wandu, and Richard K. Wilson

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Variation in practice regarding pretreatment with dual antiplatelet therapy for patients with non–ST elevation myocardial infarction, Ali Shafiq, Javier Valle, Jae-Sik Jang, Mohammed Qintar, Kensey Gosch, David J. Cohen, Mandeep Singh, Richard Bach, and John A. Spertus

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Mice with genetic deletion of group VIA phospholipase A2β exhibit impaired macrophage function and increased parasite load in Trypanosoma cruzi-induced myocarditis, Janhavi Sharma, Jennifer R. Blase, Daniel F. Hoft, John O. Marentette, John Turk, and Jane McHowata

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The effect of mesenchymal stromal cell sheets on the inflammatory stage of flexor tendon healing, Hua Shen, Ioannis Kormpakis, Necat Havlioglu, Stephen W. Linderman, Shelly E. Sakiyama-Elbert, Isaac E. Erickson, Thomas Zarembinski, Matthew J. Silva, Richard H. Gelberman, and Stavros Thomopoulos

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Massively parallel cis-regulatory analysis in the mammalian central nervous system, Susan Q. Shen, Connie A. Myers, Andrew E.O. Hughes, Leah C. Byrne, John G. Flannery, and Joseph C. Corbo

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X. couchianus and X. hellerii genome models provide genomic variation insight among Xiphophorus species, Yingjia Shen, Domitille Chalopin, Tzintzuni Garcia, Mikki Boswell, William Boswell, Sergey A. Shiryev, Richa Agarwala, Jean-Nicolas Volff, John H. Postlethwait, Manfred Scharti, Patrick Minx, Wesley C. Warren, and Ronald B. Walter

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Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells, Daniel W. Sherbenou, Blake T. Aftab, Yang Su, Christopher R. Behrens, Arun Wiita, Aaron C. Logan, Diego Acosta-Alvear, Byron C. Hann, Peter Walter, Marc A. Shuman, Xiaobo Wu, John P. Atkinson, Jeffrey L. Wolf, Thomas G. Martin, and Bin Liu

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Human metabolome-derived cofactors are required for the antibacterial activity of siderocalin in urine, Robin R. Shields-Cutler, Jan R. Crowley, Connelly D. Miller, Ann E. Stapleton, Weidong Cui, and Jeffery P. Henderson

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Quantitative analysis of high-resolution microendoscopic images for diagnosis of neoplasia in patients with Barrett’s esophagus, Dongsuk Shin, Michelle H. Lee, Alexandros D. Polydorides, Mark C. Pierce, Peter M. Vila, Neil D. Parikh, Daniel G. Rosen, Sharmila Anandasabapathy, and Rebecca R. Richards-Kortum

Activation of the Caenorhabditis elegans degenerin channel by shear stress requires the MEC-10 subunit, Shujie Shi, Cliff J. Luke, Mark T. Miedel, Gary A. Silverman, and Thomas R. Kleyman

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Cardiac arrest-induced global brain hypoxia-ischemia during development affects spontaneous activity organization in rat sensory and motor thalamocortical circuits during adulthood, Michael Shoykhet and Jason W. Middleton

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The complement system component C5a produces thermal hyperalgesia via macrophage-to-nociceptor signaling that requires NGF and TRPV1, Leonid P. Shutov, Charles A. Warwick, Xiaoyu Shi, Aswini Gnanasekaran, Andrew J. Shepherd, Durga P. Mohapatra, Trent M. Woodruff, J. David Clark, and Yuriy M. Usachev

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The human experience with intravenous levodopa, Shan H. Siddiqi, Natalia K. Abraham, Christopher L. Geiger, Morvarid Karimi, Joel S. Perlmutter, and Kevin J. Black

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The influence of temperament and character profiles on specialty choice and well-being in medical residents, Martin Sievert, Igor Zwir, Kevin M. Cloninger, Nigel Lester, Sandor Rozsa, and C. Robert Cloninger

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Correlation and reliability of cervical sagittal alignment parameters between lateral cervical radiograph and lateral whole-body EOS stereoradiograph, Weerasak Singhatanadgige, Daniel G. Kang, Panya Luksanapruksa, Colleen Peters, and K. Daniel Riew

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Tubular overexpression of Angiopoietin-1 attenuates renal fibrosis, Sudhir Singh, Scott R. Manson, Heedoo Lee, Yeawon Kim, Tuoen Liu, Qiusha Guo, Julio J. Geminiani, Paul F. Austin, and Ying Maggie Chen

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Study Protocol: A randomized controlled trial evaluating the effect of family-based behavioral treatment of childhood and adolescent obesity–The FABO-study, Hanna F. Skjåkødegård, Yngvild S. Danielsen, Mette Morken, Sara-Rebekka F. Linde, Rachel P. Kolko, Katherine N. Balantekin, Denise W. Wilfley, and Pétur B. Júlíusson

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High-protein intake during weight loss therapy eliminates the weight-loss-induced improvement in insulin action in obese postmenopausal women, Gordon I. Smith, Jun Yoshino, Shannon C. Kelly, Dominic N. Reeds, Adewole Okunade, Bruce W. Patterson, Samuel Klein, and Bettina Mittendorfer

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Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival, Laura J. Smithson and David H. Gutmann

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Acidic extracellular pH of tumors induces octamer-binding transcription factor 4 expression in murine fibroblasts in vitro and in vivo, Avik Som, Sharon Bloch, Joseph E. Ippolito, and Samuel Achilefu

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Cetuximab plus platinum-based chemotherapy in head and neck squamous cell carcinoma: A randomized, double-blind safety study comparing cetuximab produced from two manufacturing processes using the EXTREME study regimen, Denis Soulieres, Jose Luis Aguilar, Eric Chen, Krzysztof Misiukiewicz, Scott Ernst, Hyun Jung Lee, Katherine Bryant, Shuang He, Coleman K. Obasaju, Shao-Chun Chang, Steve Chin, and Douglas Adkins

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A content analysis of vaping advertisements on Twitter, November 2014, Shaina J. Sowles, Melissa J. Krauss, Sarah Connolly, and Patricia A. Cavazos-Rehg

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Adhesive pili in UTI pathogenesis and drug development, Caitlin N. Spaulding and Scott J. Hultgren

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The Brief Case: Dyspnea in a profoundly immunocompromised man, Andrej Spec, Carlos A.Q. Santos, and Morgan A. Pence

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T cells from patients with Candida sepsis display a suppressive immunophenotype, Andrej Spec, Yuichiro Shindo, Carey-Ann D. Burnham, Strother Wilson, Enyo A. Ablordeppey, Evan R. Beiter, Katherine Chang, Anne M. Drewry, and Richard S. Hotchkiss

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Exported epoxide hydrolases modulate erythrocyte vasoactive lipids during Plasmodium falciparum infection, Natalie J. Spillman, Varun K. Dalmia, and Daniel E. Goldberg

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Combinatorial cis-regulation in Saccharomyces species, Aaron T. Spivak and Gary D. Stormo

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The effects of peripheral and central high insulin on brain insulin signaling and amyloid-β in young and old APP/PS1 mice, Molly Stanley, Shannon L. Macauley, Emily E. Caesar, Lauren J. Koscal, Will Moritz, Grace O. Robinson, Joseph Roh, Jennifer Keyser, Hong Jiang, and David M. Holtzman

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Changes in insulin and insulin signaling in Alzheimer's disease: Cause or consequence?, Molly Stanley, Shannon L. Macauley, and David M. Holtzman

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Negative emotional reactivity as a marker of vulnerability in the development of borderline personality disorder symptoms, Stephanie D. Stepp, Lori N. Scott, Neil P. Jones, Diana J. Whalen, and Alison E. Hipwell

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Emerging executive functioning and motor development in infants at high and low risk for autism spectrum disorder, Tanya St. John, Annette M. Estes, Stephen R. Dager, Penelope Kostopoulos, Jason J. Wolff, Juhi Pandey, Jed T. Elison, Sarah J. Paterson, Robert T. Schultz, Kelly Botteron, Heather Hazlett, and Joseph Piven

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Proficient replication of the yeast genome by a viral DNA polymerase, Joseph L. Stodola, Carrie M. Stith, and Peter M. Burgers

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Oxidative DNA damage stalls the human mitochondrial replisome, Gorazd Stojkovič, Alena V. Makarova, Paulina H. Wanrooij, Josefin Forslund, Peter M. Burgers, and Sjoerd Wanrooij

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NAMPT-mediated NAD+ biosynthesis in adipocytes regulates adipose tissue function and multi-organ insulin sensitivity in mice, Kelly L. Stromsdorfer, Shintaro Yamaguchi, Myeong Jin Yoon, Anna C. Moseley, Michael P. Franczyk, Shannon C. Kelly, Nathan Qi, Shin-ichiro Imai, and Jun Yoshino

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Extrinsic allospecific signals of hematopoietic origin dictate iNKT cell lineage-fate decisions during development, Beverly S. I. Strong, Tess J. Newkold, Amanda E. Lee, Lucas E. Turner, Amir M. Alhajjat, Jonathan W. Heusel, and Aimen F. Shaaban

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Early pregnancy vitamin D status and risk of preeclampsia, Robert C. Strunk, Leonard B. Bacharier, and et al

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Global proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogue, Kiall F. Suazo, Chad Schaber, Charuta C. Palsuledesai, Audrey R. Odom John, and Mark D. Distefano

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A randomized controlled trial of directive and nondirective smoking cessation coaching through an employee quitline, Walton Sumner II, Mark S. Walker, Gabrielle R. Hightstein, Irene Fischer, Yan Yan, Amy McQueen, and Edwin B. Fisher

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Fluselenamyl: A novel benzoselenazole derivative for PET detection if amyloid plaques (Aβ) in Alzheimer's disease, G.S. M. Sundaram, Dhruva D. Dhavale, Julie L. Prior, Ping Yan, John Cirrito, Nigam P. Rath, Richard Laforest, Nigel J. Cairns, Jin-Moo Lee, Paul T. Kotzbauer, and Vijay Sharma

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Mesothelin's minimal MUC16 binding moiety converts TR3 into a potent cancer therapeutic via hierarchical binding events at the plasma membrane, Yang Su, Katharina Tatzel, Xuejun Wang, Brian Belt, Pratibha Binder, Lindsay Kuroki, Matthew A. Powell, David G. Mutch, William G. Hawkins, and Dirk Spitzer

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Quantitative amyloid imaging in autosomal dominant Alzheimer’s disease: Results from the DIAN study group, Yi Su, Tyler M. Blazey, Christopher J. Owen, Jon J. Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C. Hornbeck, Beau M. Ances, Abraham Z. Snyder, Lisa A. Cash, Eric McDade, Chengjie Xiong, Daniel S. Marcus, John C. Morris, Randall J. Bateman, Tammie L. S. Benzinger, and et al.

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Myeloid deletion of nemo causes osteopetrosis in mice owing to upregulation of transcriptional repressors, Gaurav Swarnkar, Kyuhwan Shim, Amjad M. Nasir, Kuljeet Seehra, Hung-Po (Tim) Chen, Gabriel Mbalaviele, and Yousef Abu-Amer

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Exploring associations between perceived home and work neighborhood environments, diet behaviors, and obesity: Results from a survey of employed adults in Missouri, Rachel Tabak, J. Aaron Hipp, Elizabeth A. Dodson, Lin Yang, Deepti Adlakha, and Ross C. Brownson

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Comparison of open gastrostomy tube to percutaneous endoscopic gastrostomy tube in lung transplant patients, Sharven Taghavi, Vishnu Ambur, Senthil Jayarajan, John Gaughan, Yoshiya Toyoda, Elizabeth Dauer, Lars Ola Sjoholm, Abhijit Pathak, Thomas Santora, and Amy J. Goldberg

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Regulation of BLM nucleolar localization, Larissa Tangeman, Michael A. McIlhatton, Patrick Grierson, Joanna Groden, and Samir Acharya

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Bronchospasm in obese patients undergoing elective laparoscopic surgery under general anesthesia, Vassilios Tassoudis, Hronis Ieropoulos, Menelaos Karanikolas, George Vretzakis, Aik Bouzia, Elias Mantoudis, and Argyro Petsiti

Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: implications for drug development and basic cytokine biology, Katharina Tatzel, Lindsay Kuroki, Igor Dmitriev, Elena Kashentseva, David T. Curiel, S. Peter Goedegebuure, Matthew A. Powell, David G. Mutch, William G. Hawkins, and Dirk Spitzer

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Molecular signatures of natural selection for polymorphic genes of the human dopaminergic and serotonergic systems: A review, Daniel R. Taub and Joshua Page

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Postoperative severe headache following cervical posterior surgical fixation from C2 distally, Ryoji Tauchi, Sang-Hun Lee, Jin-Young Kim, Yong-Chan Kim, Colleen Peters, Shiro Imagama, Naoki Ishiguro, Jacob Buchowski, and K. Daniel Riew

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Postoperative severe headache following cervical posterior surgical fixation from C2 distally, Ryoji Tauchi, Sang-Hun Lee, Jin-Young Kim, Yong-Chan Kim, Colleen Peters, Shiro Imagama, Naoki Ishiguro, Jacob Buchowski, and K. Daniel Riew

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Cervical myeloradiculopathy due to ossification of the posterior longitudinal ligament with versus without diffuse idiopathic spinal hyperostosis, Ryoji Tauchi, Sang-Hun Lee, Colleen Peters, Shiro Imagama, Naoki Ishiguro, and K. Daniel Riew

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Assessing heterogeneity of osteolytic lesions in multiple myeloma by1H HR-MAS NMR metabolomics, Laurette Tavel, Francesca Fontana, Josè Manuel Garcia Manteiga, Silvia Mari, Elisabetta Mariani, Enrico Caneva, Roberto Sitia, Francesco Camnasio, Magda Marcatti, Simone Cenci, and Giovanna Musco

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A genome-wide study of blood pressure in African Americans accounting for gene-smoking interaction, Jacquelyn Y. Taylor, Karen Schwander, Sharon L. R. Kardia, Donna Arnett, Jingjing Liang, Steven C. Hunt, D C. Rao, and Yan V. Sun

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Identification of a novel fusion transcript between human relaxin-1 (RLN1) and human relaxin-2 (RLN2) in prostate cancer, Gregor Tevz, Sean McGrath, Ryan Demeter, Vincent Magrini, Varinder Jeet, Anja Rockstroh, Stephen McPherson, John Lai, Nenad Bartonicek, Jiyuan An, Jyotsna Batra, Marcel E. Dinger, Melanie L. Lehman, Elizabeth D. Williams, and Colleen C. Nelson

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Chronic methamphetamine effects on brain structure and function in rats, Panayotis K. Thanos, Ronald Kim, Foteini Delis, Mala Ananth, George Chachati, Mark J. Rocco, Ihssan Masad, Jose A. Muniz, Samuel C. Grant, Mark S. Gold, Jean Lud Cadet, and Nora D. Volkow

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RNF4-dependent oncogene activation by protein stabilization, Jane J. Thomas, Mona Abed, Julian Heuberger, Rostislav Novak, Yaniv Zohar, Angela P. Beltran Lopez, Julie S. Trausch-Azar, Ma. Xenia G. Ilagan, David Benhamou, Gunnar Dittmar, Raphael Kopan, Walter Birchmeier, Alan L. Schwartz, and Amir Orian