The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2020

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Higher cortical dysfunction presenting as visual symptoms in neurodegenerative diseases, Yin Liu, Victoria S Pelak, Gregory van Stavern, and Heather E Moss

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Hepatic lipids promote liver metastasis, Yongjia Li, Xinming Su, Nidhi Rohatgi, Yan Zhang, Jonathan R Brestoff, Kooresh I Shoghi, Yalin Xu, Clay F Semenkovich, Charles A Harris, Lindsay L Peterson, Katherine N Weilbaecher, Steven L Teitelbaum, and Wei Zou

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Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17, Local Burden of Disease Diarrhoea Collaborators, Ziyad Al-Aly, and et al

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The tip of the VgrG spike is essential to functional type VI secretion system assembly in Acinetobacter baumannii, Juvenal Lopez, Pek Man Ly, and Mario F Feldman

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Mapping of the language network with deep learning, Patrick Luckett, John J Lee, Ki Yun Park, Donna Dierker, Andy G S Daniel, Benjamin A Seitzman, Carl D Hacker, Beau M Ances, Eric C Leuthardt, Abraham Z Snyder, and Joshua S Shimony

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Regulation of signaling and metabolism by lipin-mediated phosphatidic acid phosphohydrolase activity, Andrew J Lutkewitte and Brian N Finck

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Neutrophil L-plastin controls ocular paucibacteriality and susceptibility to keratitis, Xiaoxiao Lu, Abirami Kugadas, Kirsten Smith-Page, Jeffrey Lamb, Tiffany Lin, Yusha Ru, Sharon Celeste Morley, Raina Fichorova, Sharad K Mittal, Sunil K Chauhan, Sejiro Littleton, Daniel Saban, and Mihaela Gadjeva

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Lack of neurosteroid selectivity at δ vs. γ2-containing GABAA receptors in dentate granule neurons, Xinguo Lu, Charles F Zorumski, and Steven Mennerick

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A new gorilla adenoviral vector with natural lung tropism avoids liver toxicity and is amenable to capsid engineering and vector retargeting, Zhi Hong Lu, Igor P. Dmitriev, Douglas E. Brough, Elena A. Kashentseva, Jie Li, and David T. Curiel

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Gene-by-gene interactions associated with the risk of conotruncal heart defects, Chen Lyu, Daniel M Webber, Stewart L MacLeod, Charlotte A Hobbs, Ming Li, and National Birth Defects Prevention Study

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Barrier-to-autointegration factor 1 protects against a basal cGAS-STING response, Hongming Ma, Wei Qian, Monika Bambouskova, Patrick L Collins, Sofia I Porter, Andrea K Byrum, Rong Zhang, Maxim Artyomov, Eugene M Oltz, Nima Mosammaparast, Jonathan J Miner, and Michael S Diamond

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Photoreceptor responses to light in the pathogenesis of diabetic retinopathy, Shahriyar P Majidi and Rithwick Rajagopal

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Enteric viral co-infections: Pathogenesis and perspective, Heyde Makimaa, Harshad Ingle, and Megan T Baldridge

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Five-year outcomes of transcatheter or surgical aortic-valve replacement, Raj R. Makkar, Alan Zajarias, and et al.

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Incomplete vesicular docking limits synaptic strength under high release probability conditions, Gerardo Malagon, Takafumi Miki, Van Tran, Laura C. Gomez, and Alain Marty

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Understanding antibiotic prophylaxis prescribing in pediatric surgical specialties, Sara M Malone, Natalie S Seigel, Jason G Newland, Jacqueline M Saito, and Virginia R McKay

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Molecular characterization of sarcomatoid clear cell renal cell carcinoma unveils new candidate oncogenic drivers, Gabriel G. Malouf, James J. Hsieh, and et al.

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Tumor infiltrating neutrophils are enriched in basal-type urothelial bladder cancer, Giulio Eugenio Mandelli, Francesco Missale, Debora Bresciani, Luisa Benerini Gatta, Patrizia Scapini, Elena Caveggion, Elisa Roca, Mattia Bugatti, Matilde Monti, Luca Cristinelli, Sandra Belotti, Claudio Simeone, Stefano Calza, Laura Melocchi, and William Vermi

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Tamoxifen acts as a parietal cell protonophore, E H Manning, L A Lapierre, J C Mills, and J R Goldenring

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Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801, Guido Marcucci, Geoffrey L. Uy, and et al.

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Spatiotemporal dynamics of multi-vesicular release is determined by heterogeneity of release sites within central synapses, Dario Maschi and Vitaly A. Klyachko

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Mental health and weather extremes in a Southeastern U.S. city: Exploring group differences by race, Lisa Reyes Mason, Bonita B Sharma, Jayme E Walters, and Christine C Ekenga

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Knowledge base and perceptions of inpatient providers and parents about influenza vaccination in hospitalized children, Shakila Mathew and Mythili Srinivasan

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Impact of intraoperative ocular lubricants on corneal debridement rate during vitreoretinal surgery, Michael L Mathison, Albert S Li, Yicheng K Bao, Andrew Jw Huang, and Rithwick Rajagopal

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A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration, Yuki Matsushita, Mizuki Nagata, Kenneth M. Kozloff, Joshua D. Welch, Koji Mizuhashi, Nicha Tokavanich, Shawn A. Hallett, Daniel C. Link, Takashi Nagasawa, Wanida Ono, and Noriaki Ono

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Individualization of attention-deficit/hyperactivity disorder treatment: Pharmacotherapy considerations by age and co-occurring conditions, Greg W Mattingly, Joshua Wilson, Leticia Ugarte, and Paul Glaser

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Obesity is a risk factor for acute promyelocytic leukemia: Evidence from population and cross-sectional studies and correlation with FLT3 mutations and polyunsaturated fatty acid metabolism, Luca Mazzarella, Timothy J. Ley, and et al.

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Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity, Conor McClenaghan, Yan Huang, Zihan Yan, Theresa M Harter, Carmen M Halabi, Rod Chalk, Attila Kovacs, Gijs van Haaften, Maria S Remedi, and Colin G Nichols

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The pathway to secondary prevention of Alzheimer's disease, Eric McDade, Martin M Bednar, H Robert Brashear, David S Miller, Paul Maruff, Christopher Randolph, Zahinoor Ismail, Maria C Carrillo, Christopher J Weber, Lisa J Bain, and Ann Marie Hake

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Mass spectrometry– based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells, Ian M. McDonald, Gavin D. Grant, Michael P. East, Thomas S.K. Gilbert, Emily M. Wilkerson, Dennis Goldfarb, Joshua Beri, Laura E. Herring, Cyrus Vaziri, Jeanette Gowen Cook, Michael J. Emanuele, and Lee M. Graves

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Circulating ceramide ratios and risk of vascular brain aging and dementia, Emer R McGrath, Jayandra J Himali, Vanessa Xanthakis, Meredith S Duncan, Jean E Schaffer, Daniel S Ory, Linda R Peterson, Charles DeCarli, Matthew P Pase, Claudia L Satizabal, Ramachandran S Vasan, Alexa S Beiser, and Sudha Seshadri

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Assessing the relationship between district and state policies and school nutrition promotion-related practices in the United States, Gabriella M McLoughlin, Lindsey Turner, Julien Leider, Elizabeth Piekarz-Porter, and Jamie F Chriqui

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Clinical care recommendations for cardiologists treating adults with myotonic dystrophy, Elizabeth M McNally, Douglas L Mann, Yigal Pinto, Deepak Bhakta, Gordon Tomaselli, Saman Nazarian, William J Groh, Takuhisa Tamura, Denis Duboc, Hideki Itoh, Leah Hellerstein, and Pradeep P A Mammen

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Cefazolin inoculum effect and methicillin-susceptible Staphylococcus aureus osteoarticular infections in children, J Chase McNeil, Lauren M Sommer, Mary Boyle, Patrick Hogan, Jesus G Vallejo, Kristina G Hultén, Anthony R Flores, Sheldon L Kaplan, and Stephanie Fritz

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Paratubal serous borderline tumor in an 85 years old woman: A case report, Jordy Mehawej, Nicole El Helou, Lina Wang, and Paulette Mhawech-Fauceglia

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The struggling infectious diseases fellow: Remediation challenges and opportunities, Michael T. Melia, Gerome Escota, and et al

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Disrupting flight increases sleep and identifies a novel sleep-promoting pathway in Drosophila, K Melnattur, B Zhang, and P J Shaw

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Comparison of three magnetization transfer ratio parameters for assessment of intestinal fibrosis in patients with Crohn’s disease, Jixin Meng, Siyun Huang, CanHui Sun, Zhong-wei Zhang, Ren Mao, Yan-hong Yang, Shi-Ting Feng, Zi-ping Li, and XueHua Li

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Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker, Rajasree Menon, Sanjay Jain, and et al

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Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes, Marica Meroni, Nicholas O Davidson, and et al

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Rituximab/bendamustine and rituximab/cytarabine induction therapy for transplant-eligible mantle cell lymphoma, Reid W. Merryman, Natasha Edwin, Amanda Cashen, Nancy L. Bartlett, Neha Mehta-Shah, Armin Ghobadi, Brad Kahl, and et al.

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Mouse genetics identifies unique and overlapping functions of fibroblast growth factor receptors in keratinocytes, Michael Meyer, Maya Ben-Yehuda Greenwald, Theresa Rauschendorfer, Catharina Sänger, Marko Jukic, Haruka Iizuka, Fumimasa Kubo, Lin Chen, David M Ornitz, and Sabine Werner

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Characteristics and outcomes among a hospitalized patient cohort with Streptococcus pneumoniae infection, Scott T. Micek, James Simmons, Nicholas Hampton, and Marin H. Kollef

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Genomics of MPNST (GeM) consortium: Rationale and study design for multi-omic characterization of NF1-associated and sporadic MPNSTs, David T Miller, Angela C Hirbe, and et al

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Metabolic tumor volume response assessment using (11)C-methionine positron emission tomography identifies glioblastoma tumor subregions that predict progression better than baseline or anatomic magnetic resonance imaging alone, Sean Miller, Matthew Schipper, Larry Junck, Morand Piert, Theodore S. Lawrence, Christina Tsien, Yue Cao, and Michelle M. Kim

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Phase 1–2 trial of antisense oligonucleotide tofersen for SOD1 ALS, Timothy Miller, Robert C. Bucelli, Alan Pestronk, and et al.

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Human brain functional network organization is disrupted after whole-brain radiation therapy, Timothy J. Mitchell, Benjamin A. Seitzman, Nicholas Ballard, Steven E. Petersen, Joshua S. Shimony, and Eric C. Leuthardt

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Detecting pneumonia using convolutions and dynamic capsule routing for chest X-ray images, Ansh Mittal, Deepika Kumar, Mamta Mittal, Tanzila Saba, Ibrahim Abunadi, Amjad Rehman, and Sudipta Roy

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Multiple network disconnection in anosognosia for hemiplegia, Elena Monai, Francesca Bernocchi, Marta Bisio, Antonio Luigi Bisogno, Alessandro Salvalaggio, and Maurizio Corbetta

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The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth, Baisakhi Mondal, Hongjian Jin, Satish Kallappagoudar, Yurii Sedkov, Tanner Martinez, Monica F. Sentmanat, Greg J. Poet, Chunliang Li, Yiping Fan, Shondra M. Pruett-Miller, and Hans-Martin Herz

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A retrospective analysis of the efficacy of immunotherapy in metastatic soft-tissue sarcomas, Varun Monga, Hilary Dietz, Angela C Hirbe, Brian A Van Tine, Peter Oppelt, and et al

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Non-conventional treatments for conventional chondrosarcoma, Varun Monga, Hariharasudan Mani, Angela Hirbe, and Mohammed Milhem

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Human plasmacytoid dendritic cells and cutaneous melanoma, Matilde Monti, Francesca Consoli, Raffaella Vescovi, Mattia Bugatti, and William Vermi

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Plasmacytoid dendritic cell impairment in metastatic melanoma by lactic acidosis, Matilde Monti, Raffaella Vescovi, Francesca Consoli, Davide Farina, Daniele Moratto, Alfredo Berruti, Claudia Specchia, and William Vermi

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Unmasking intra-tumoral heterogeneity and clonal evolution in NF1-MPNST, Chang-In Moon, William Tompkins, Yuxi Wang, Abigail Godec, Xiaochun Zhang, Patrik Pipkorn, Christopher A Miller, Carina Dehner, Sonika Dahiya, and Angela C Hirbe

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ProteoClade: A taxonomic toolkit for multi-species and metaproteomic analysis, Arshag D. Mooradian, Sjoerd van der Post, Kristen M. Naegle, and Jason M. Held

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Both unmedicated and medicated individuals with schizophrenia show impairments across a wide array of cognitive and reinforcement learning tasks, Erin K Moran, James M Gold, Cameron S Carter, Angus W MacDonald, J Daniel Ragland, Steven M Silverstein, Steven J Luck, and Deanna M Barch

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The non-coding RNA landscape of plasma cell dyscrasias, Eugenio Morelli, Roberta Rocca, Kareem A Azab, and et al

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Parcel-guided rTMS for depression, M. Moreno Ortega, A. Kangarlu, S. Lee, T. Perera, J. Kangarlu, T. Palomo, M.F. Glasser, and D.C. Javitt

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Gardnerella vaginalis as a cause of bacterial vaginosis: Appraisal of the evidence from in vivo models, Sydney Morrill, Nicole M Gilbert, and Amanda L Lewis

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The quail genome: Insights into social behaviour, seasonal biology and infectious disease response, Katrina M Morris, LaDeana W Hillier, Patrick Minx, Chad Tomlinson, and et al

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Proof-of-concept study of the efficacy of a microbiota-directed complementary food formulation (MDCF) for treating moderate acute malnutrition, Ishita Mostafa, Naila Nurun Nahar, Md Munirul Islam, Sayeeda Huq, Mahfuz Mustafa, Michael Barratt, Jeffrey I Gordon, and Tahmeed Ahmed

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Harnessing real-world data to inform decision-making: Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS), Ellen M Mowry, Tammie L S Benzinger, Robert T Naismith, and et al

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Are we ready to share qualitative research data? Knowledge and preparedness among qualitative researchers, IRB Members, and data repository curators, Jessica Mozersky, Heidi Walsh, Meredith Parsons, Tristan McIntosh, Kari Baldwin, and James M DuBois

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Counseling on Access to Lethal Means-Emergency Department (CALM-ED): A quality improvement program for firearm injury prevention, Kristen L Mueller, Sonya Naganathan, and Richard T Griffey

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Combining stage specificity and metabolomic profiling to advance antimalarial drug discovery, James M Murithi, Edward S Owen, Eva S Istvan, Marcus C S Lee, Sabine Ottilie, Kelly Chibale, Daniel E Goldberg, Elizabeth A Winzeler, Manuel Llinás, David A Fidock, and Manu Vanaerschot

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Challenges and solutions for the implementation of shared decision-making in breast reconstruction, Terence M. Myckatyn, Rajiv P. Parikh, Clara Lee, and Mary C. Politi

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2019 Pediatric Initiative Network: Progress, proceedings, and plans, Leena Nahata, Veronica Gomez-Lobo, Lillian Meacham, Leslie Appiah, Krista Childress, Holly Hoefgen, Maggie Dwiggins, Stacy Whiteside, Kari Bjornard, Julie Rios, Antoinette Anazodo, Courtney Finlayson, Olivia Frias, Teresa Woodruff, and Molly Moravek

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Amelioration of congenital tufting enteropathy in EpCAM (TROP1)-deficient mice via heterotopic expression of TROP2 in intestinal epithelial cells, Gaku Nakato, Sohshi Morimura, Michael Lu, Xu Feng, Chuanjin Wu, and Mark C Udey

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Amelioration of congenital tufting enteropathy in EpCAM (TROP1)-deficient mice via heterotopic expression of TROP2 in intestinal epithelial cells, Gaku Nakato, Sohshi Morimura, Michael Lu, Xu Feng, Chuanjin Wu, and Mark C Udey

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Malaria parasite plasmepsins: More than just plain old degradative pepsins, Armiyaw S. Nasamu, Alexander J. Polino, Eva S. Istvan, and Daniel E. Goldberg

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Clinical teaching: An evidence-based guide to best practices from the Council of Emergency Medicine Residency Directors, Sreeja Natesan, John Bailitz, Andrew King, Sara M Krzyzaniak, Sarah K Kennedy, Albert J Kim, Richard Byyny, and Michael Gottlieb

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Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability, Sumeet Nayak, Jennifer A Calvo, Ke Cong, Min Peng, Emily Berthiaume, Jessica Jackson, Angela M Zaino, Alessandro Vindigni, M Kyle Hadden, and Sharon B Cantor

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Targeting unconventional host components for vaccination-induced protection against TB, Elisa Nemes, Shabaana A Khader, Rosemary V Swanson, and Willem A Hanekom

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Precise breakpoint detection in a patient with 9p- syndrome, Jeffrey Ng, Eleanor Sams, Dustin Baldridge, Milinn Kremitzki, Daniel J Wegner, Tina Lindsay, Robert Fulton, F Sessions Cole, and Tychele N Turner

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A mobile app directory of occupational therapists who provide home modifications: Development and preliminary usability evaluation, An Thi Nguyen, Emily Kling Somerville, Sandra Martina Espín-Tello, Marian Keglovits, and Susan Lynn Stark

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Abatacept is effective as GVHD prophylaxis in unrelated donor stem cell transplantation for children with severe sickle cell disease, Alexander Ngwube, Niketa Shah, Kamar Godder, David Jacobsohn, Monica L. Hulbert, and Shalini Shenoy

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Self-perception of physical function contributes to participation in cognitively- and physically-demanding activities after stroke, Marjorie L Nicholas, Kari Burch, Julianne R Mitchell, Annie B Fox, Carolyn M Baum, and Lisa Tabor Connor

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Treatment of oligometastatic lung cancer with brain metastases using stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), John Nikitas, Michael Roach, Cliff Robinson, Jeffrey Bradley, Jiayi Huang, Stephanie Perkins, Christina Tsien, and Christopher Abraham

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Lathosterol oxidase (sterol C-5 desaturase) deletion confers resistance to amphotericin B and sensitivity to acidic stress in Leishmania major, Yu Ning, Cheryl Frankfater, Fong-Fu Hsu, Rodrigo P Soares, Camila A Cardoso, Paula M Nogueira, Noelia Marina Lander, Roberto Docampo, and Kai Zhang

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Youth participatory research evidence to inform health policy: A systematic review protocol, Janet Njelesani and Jean Hunleth

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Pattern of relapse and treatment response in WNT-activated medulloblastoma, Liana Nobre, Joshua B Rubin, and et al

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Zika virus infection in the developing mouse produces dramatically different neuropathology dependent on viral strain, Kevin K. Noguchi, Brant S. Swiney, Sasha L. Williams, Jacob N. Huffman, Katherine Lucas, Sophie H. Wang, Kayla M. Kapral, Amber Li, and Krikor T. Dikranian

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Lung transplant pulmonologists’ views of specialty palliative care for lung transplant recipients, Eric Nolley, Jessica Fleck, Dio Kavalieratos, Mary Amanda Dew, Daniel Dilling, Rebecca Colman, Maria M. Crespo, Hilary Goldberg, Steven Hays, Ramsey Hachem, Erika Lease, James Lee, John Reynolds, Matthew Morrell, and Yael Schenker

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Association of PTSD symptom groups with functional impairment and distress in trauma-exposed disaster survivors, Carol S North, Erin Van Enkevort, Barry A Hong, and Alina M Surís

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Pediatric ADHD symptom burden relates to distinct neural activity across executive function domains, Tehila Nugiel, Mary Abbe Roe, Laura E Engelhardt, Mackenzie E Mitchell, Annie Zheng, and Jessica A Church

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Focal dynamic thermal imaging for label‑free high‑resolution characterization of materials and tissue heterogeneity, Christine M. O'Brien, Hongyu Meng, Leonid Shmuylovich, Julia Carpenter, Praneeth Gogineni, Haini Zhang, Kevin Bishop, Suman B. Mondal, Gail P. Sudlow, Cheryl Bethea, Clyde Bethea, and Samuel Achilefu

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Increase in superficial dose in whole-breast irradiation with Halcyon straight-through linac compared with traditional C-arm linac with flattening filter: In vivo dosimetry and planning study, Fionnbarr O'Grady, Andrew R. Barsky, Shibu Anamalayil, Gary M. Freedman, Christopher Kennedy, Bin Cai, Eric Laugeman, Lei Dong, Geoffrey D. Hugo, James M. Metz, Sasa Mutic, Neil K. Taunk, and Taoran Li

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Macrophage secretion of miR-106b-5p causes renin-dependent hypertension, J. Oh, S. J. Matkovich, A. E. Riek, S. M. Bindom, J. S. Shao, R.D. Head, R. A. Barve, M. S. Sands, G. Carmeliet, P. Osei-Owusu, R.H. Knutsen, H. Zhang, K. J. Blumer, C. G. Nichols, R. P. Mecham, Á Baldán, B. A. Benitez, M. L. Sequeira-Lopez, R. A. Gomez, and C. Bernal-Mizrachi

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Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies, Tatiana Orme, Nigel J Cairns, John C Morris, and et al

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Uncovering tumour heterogeneity through PKR and nc886 analysis in metastatic colon cancer patients treated with 5-FU-based chemotherapy, María Belén Ortega-García, Igor Zwir, and et al

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Divergent effects of DNMT3A and TET2 mutations on hematopoietic progenitor cell fitness, Elizabeth L Ostrander, Ashley C Kramer, Cates Mallaney, Hamza Celik, Won Kyun Koh, Jake Fairchild, Emily Haussler, Christine R C Zhang, and Grant A Challen

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Nutrition in necrotizing enterocolitis and following intestinal resection, Jocelyn Ou, Cathleen M Courtney, Allie E Steinberger, Maria E Tecos, and Brad W Warner

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In situ detection of endogenous HIV activation by dynamic nuclear polarization NMR and flow cytometry, Sarah A Overall, Lauren E Price, Brice J Albert, Chukun Gao, Nicholas Alaniva, Patrick T Judge, Erika L Sesti, Paul A Wender, George B Kyei, and Alexander B Barnes

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Interleukin-15 superagonist (N-803) treatment of PML and JCV in a post–allogeneic hematopoietic stem cell transplant patient, Aabha Oza, Michael P. Rettig, Phil Powell, Kathryn O'Brien, David B. Clifford, Julie Ritchey, Leah Gehrs, Julia Hollaway, Eugene Major, Todd A. Fehniger, Christopher A. Miller, Patrick Soon-Shiong, Amy Rock, and John F. DiPersio

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Experience-dependent resonance in amygdalocortical circuits supports fear memory retrieval following extinction, Minagi Ozawa, Patrick Davis, Jianguang Ni, Jamie Maquire, Thomas Papouin, and Leon Reijmers

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Feasibility and safety of focused ultrasound-enabled liquid biopsy in the brain of a porcine model, Christopher Pham Pacia, Lifei Zhu, Yaoheng Yang, Yimei Yue, Arash Nazeri, H. Michael Gach, Michael R. Talcott, Eric C. Leuthardt, and Hong Chen

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Reconstruction of severe palm injury with sensate medial plantar artery flap and nerve grafting, William M. Padovano, Elspeth J.R. Hill, and John M. Felder III

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In utero exposure to transient ischemia-hypoxemia promotes long-term neurodevelopmental abnormalities in male rat offspring, Arvind Palanisamy, Tusar Giri, Jia Jiang, Annie Bice, James D Quirk, Sara B Conyers, Susan E Maloney, Nandini Raghuraman, Adam Q Bauer, Joel R Garbow, and David F Wozniak

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Clinical and functional significance of circular RNAs in cytogenetically normal AML, Dimitrios Papaioannou, Geoffrey L. Uy, and et al.