The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2022

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Measurement of gender and sexuality in the Adolescent Brain Cognitive Development (ABCD) study, Alexandra S Potter, Hailee Jefferys, and et al

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Socioeconomic risk markers of arthropod-borne virus (arbovirus) infections: A systematic literature review and meta-analysis, Grace M Power, Aisling M Vaughan, Luxi Qiao, Nuria Sanchez Clemente, Julia M Pescarini, Enny S Paixão, Ludmila Lobkowicz, Amber I Raja, André Portela Souza, Mauricio Lima Barreto, and Elizabeth B Brickley

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PFTAIRE kinase L63 interactor 1A (Pif1A protein) is required for actin cone movement during spermatid individualization in Drosophila melanogaster, Harrison D Pravder, Dorota Grabowska, Kaushik Roychoudhury, Betty Zhang, Deborah Frank, Przemysław Zakrzewski, Marta Lenartowska, and Kathryn G Miller

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Commissioning a secondary dose calculation software for a 0.35 T MR-linac, Alex T Price, Nels C Knutson, Taeho Kim, and Olga L Green

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Molecular dissection of RbpA-mediated regulation of fidaxomicin sensitivity in mycobacteria, Jerome Prusa, Dennis X Zhu, Aidan J Flynn, Drake Jensen, Ana Ruiz Manzano, Eric A Galburt, and Christina L Stallings

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Mitigating the effects of COVID-19 on HIV treatment and care in Lusaka, Zambia: A before-after cohort study using mixed effects regression, Jake Pry, Kombatende Sikombe, Aaloke Mody, Shilpa Iyer, Jacob Mutale, Natalie Vlahakis, Theodora Savory, Mwanza Wa Mwanza, Keith Mweebo, Annie Mwila, Consity Mwale, Mpande Mukumbwa-Mwenechanya, Andrew Kerkhoff, Izukanji Sikazwe, Carolyn Bolton Moore, Daniel Mwamba, Elvin Geng, and Michael Herce

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Procedural Risk in Congenital Cardiac Catheterization (PREDIC3T), Brian P Quinn, David Balzer, and et al

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Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase, Joshua B Radke, Bruno Melillo, Payal Mittal, Manmohan Sharma, Amit Sharma, Yong Fu, Taher Uddin, Arthur Gonse, Eamon Comer, Stuart L Schreiber, Anil K Gupta, Arnab K Chatterjee, and L David Sibley

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Delphi consensus recommendation for optimization of pulmonary hypertension therapy focusing on switching from a phosphodiesterase 5 inhibitor to riociguat, Franck Rahaghi, Vijay Balasubramanian, Robert Bourge, Charles Burger, Murali Chakinala, Michael Eggert, Jean Elwing, Jeremy Feldman, Christopher King, James Klinger, Stephen Mathai, John McConnell, Harold Palevsky, Ricardo Restrepo-Jaramillo, Zeenat Safdar, Jeffrey Sager, Namita Sood, Roxana Sulica, R. James White, and Nicholas Hill

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Applying systems thinking to identify enablers and challenges to scale-up interventions for hypertension and diabetes in low-income and middle-income countries: Protocol for a longitudinal mixed-methods study, Anusha Ramani-Chander, Mark D Huffman, and et al

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Intrinsic mechanisms in the gating of resurgent Na+ currents, Joseph L. Ransdell, Jonathan D. Moreno, Druv Bhagavan, Jonathan R. Silva, and Jeanne M. Nerbonne

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Epigenetic regulation of human t‐cell leukemia virus gene expression, Lee Ratner

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Prospective nasal screening for methicillin-resistant Staphylococcus aureus in critically ill patients with suspected pneumonia, Nicholas Raush, Kevin D. Betthauser, Karen Shen, Tamara Krekel, and Marin H. Kollef

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Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma, Arja Ray, Mackenzie K. Callaway, Nelson J. Rodríguez-Merced, Alexandra L. Crampton, Marjorie Carlson, Kenneth B. Emme, Ethan A. Ensminger, Alexander A. Kinne, Jonathan H. Schrope, Haley R. Rasmussen, Hong Jiang, David G. DeNardo, David K. Wood, and Paolo P. Provenzano

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Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum, Alex Reichenbach, Alexxai V. Kravitz, and et al

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Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: The TOGETHER randomised, platform clinical trial, Gilmar Reis, Eric J Lenze, Angela M Reiersen, and et al

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Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition, Rebecca Rimbach, Susan B. Racette, John R. Speakman, Herman Pontzer, and et al

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Dopamine D4 receptor is a regulator of morphine-induced plasticity in the rat dorsal striatum, Alicia Rivera, Diana Suarez-Boomgard, Cristina Miguelez, Alejandra Valderrama-Carvajal, Jerome Baufreton, Kirill Shumilov, Anne Taupignon, Belen Gago, and M.Angeles Real

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Transcriptomes of peripheral blood mononuclear cells from juvenile dermatomyositis patients show elevated inflammation even when clinically inactive, Elisha D O Roberson, Rosana A Mesa, Gabrielle A Morgan, Li Cao, Wilfredo Marin, and Lauren M Pachman

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Genetically stable CRISPR-based kill switches for engineered microbes, Austin G Rottinghaus, Aura Ferreiro, Skye R S Fishbein, Gautam Dantas, and Tae Seok Moon

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A case of Gorham-Stout disease of the skull base treated with intensity modulated radiation therapy, Amit Roy, Neal Andruska, Randall Brenneman, Jacob Hogan, Hilary L P Orlowski, Patrik Pipkorn, and Mackenzie D Daly

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The microbial one-hit wonder, Brigida A. Rusconi and Rodney D. Newberry

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Constructing an adapted cascade of diabetes care using inpatient admissions data: Cross-sectional study, Irene Ryan, Cynthia Herrick, Mary F E Ebeling, and Randi Foraker

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Hypoxia inhibits colonic uptake of the microbiota-generated forms of vitamin B1 via HIF-1α-mediated transcriptional regulation of their transporters, Subrata Sabui, Kalidas Ramamoorthy, Jose M Romero, Rita D Simoes, James M Fleckenstein, and Hamid M Said

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Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations, Brooke Sadler, Christina A Gurnett, Jorge Di Paola, and et al

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BHLHE40 regulates the T-cell effector function required for tumor microenvironment remodeling and immune checkpoint therapy efficacy, Avery J Salmon, Alexander S Shavkunov, Qi Miao, Nicholas N Jarjour, Sunita Keshari, Ekaterina Esaulova, Charmelle D Williams, Jeffrey P Ward, Anna M Highsmith, Josué E Pineda, Reshma Taneja, Ken Chen, Brian T Edelson, and Matthew M Gubin

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From karyotypes to precision genomics in 9p deletion and duplication syndromes, Eleanor I Sams, Jeffrey K Ng, Victoria Tate, Ying-Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton, Khadija Belhassan, Julie Neidich, Robi D Mitra, F Sessions Cole, Patricia Dickson, Jeffrey Milbrandt, and Tychele N Turner

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Lipidomics analysis of outer membrane vesicles and elucidation of the inositol phosphoceramide biosynthetic pathway in Bacteroides thetaiotaomicron, Mariana G Sartorio, Ezequiel Valguarnera, Fong-Fu Hsu, and Mario F Feldman

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Low knowledge of HIV PrEP within a midwestern US cohort of persons who inject drugs, Sena Sayood, Laura R. Marks, Rupa Patel, Nathanial S. Nolan, Stephen Y. Liang, and Michael J. Durkin

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Tumor lysis syndrome in a patient with metastatic endometrial cancer treated with lattice stereotactic body radiation therapy, Joshua P Schiff, Matthew B Spraker, Sai Duriseti, Sana Shaikh, Haris F Murad, David G Mutch, Clifford G Robinson, James Kavanaugh, and Alexander J Lin

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T Cell Subtype Profiling measures exhaustion and predicts anti-PD-1 response, Ian Schillebeeckx, Jon Earls, Kevin C Flanagan, Jeffrey Hiken, Alex Bode, Jon R Armstrong, David N Messina, Douglas Adkins, Jessica Ley, Ilaria Alborelli, Philip Jermann, and Jarret I Glasscock

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Selected histone deacetylase inhibitors reverse the frataxin transcriptional defect in a novel Friedreich's ataxia induced pluripotent stem cell-derived neuronal reporter system, Anna M Schreiber, Yanjie Li, Yi-Hsien Chen, Jill S Napierala, and Marek Napierala

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Identification of small regions of overlap from copy number variable regions in patients with hypospadias, Carter H Scott and Ina E Amarillo

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Two-tier care pathways for liver fibrosis associated to non-alcoholic fatty liver disease in HIV mono-infected patients, Giada Sebastiani, Jovana Milic, Adriana Cervo, Sahar Saeed, Thomas Krahn, Dana Kablawi, Al Shaima Al Hinai, Bertrand Lebouché, Philip Wong, Marc Deschenes, Claudia Gioè, Antonio Cascio, Giovanni Mazzola, and Giovanni Guaraldi

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Severe ocrelizumab-induced enterocolitis treated successfully with ustekinumab, Janaki Shah, Ahmad Al-Taaee, Parakkal Deepak, and Anas Gremida

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Diagnostic challenges in ovarian hyperthecosis: Clinical presentation with subdiagnostic testosterone levels, Sanket Shah, Callie Torres, and Naser Gharaibeh

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Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model, Riti Sharan, Allison N Bucsan, Shabaana A Khader, and et al

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Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine, Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, and James M Fleckenstein

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Stain-free detection of embryo polarization using deep learning, Cheng Shen, Adiyant Lamba, Meng Zhu, Ray Zhang, Magdalena Zernicka-Goetz, and Changhuei Yang

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Economic choices under simultaneous or sequential offers rely on the same neural circuit, Weikang Shi, Sébastien Ballesta, and Camillo Padoa-Schioppa

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Connectomic profiling and Vagus nerve stimulation Outcomes Study (CONNECTiVOS): A prospective observational protocol to identify biomarkers of seizure response in children and youth, Lauren Siegel, Matthew D Smyth, and et al

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The fliR gene contributes to the virulence of S. marcescens in a Drosophila intestinal infection model, Bechara Sina Rahme, Matthieu Lestradet, Gisela Di Venanzio, Arshad Ayyaz, Miriam Wennida Yamba, Martina Lazzaro, Samuel Liégeois, Eleonora Garcia Véscovi, and Dominique Ferrandon

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Myeloid cell interferon responses correlate with clearance of SARS-CoV-2, Dhiraj K Singh, Ekaterina Aladyeva, Shibali Das, Bindu Singh, Ekaterina Esaulova, Amanda Swain, Mushtaq Ahmed, Journey Cole, Chivonne Moodley, Smriti Mehra, Larry S Schlesinger, Maxim N Artyomov, Shabaana A Khader, and Deepak Kaushal

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High temporal resolution measurements of movement reveal novel early-life physiological decline in C. elegans, Drew Benjamin Sinha and Zachary Scott Pincus

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Ethical, regulatory, and practical barriers to COVID-19 research: A stakeholder-informed inventory of concerns, Bryan A. Sisk, Kari Baldwin, Meredith Parsons, and James M. DuBois

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Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells, Amanda M Smith, Angela M Verdoni, Haley J Abel, David Y Chen, Shamika Ketkar, Elizabeth R Leight, Christopher A Miller, and Timothy J Ley

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The Emotional Word-Emotional Face Stroop task in the ABCD study: Psychometric validation and associations with measures of cognition and psychopathology, Harry R Smolker, Kai Wang, Monica Luciana, James M Bjork, Raul Gonzalez, Deanna M Barch, Erin C McGlade, Roselinde H Kaiser, Naomi P Friedman, John K Hewitt, and Marie T Banich

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Augmented cardiac growth hormone signaling contributes to cardiomyopathy following genetic disruption of the cardiomyocyte circadian clock, Ravi Sonkar, Ryan Berry, Mary N Latimer, Sumanth D Prabhu, Martin E Young, and Stuart J Frank

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AMIGO1 promotes axon growth and territory matching in the retina, Florentina Soto, Ning Shen, and Daniel Kerschensteiner

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Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family, Peter J Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W D'Souza, Sanket Patel, Gautam Dantas, Gerard D Wright, and Alexei Savchenko

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A novel computer adaptive word list memory test optimized for remote assessment: Psychometric properties and associations with neurodegenerative biomarkers in older women without dementia, Nikki H Stricker, John L Stricker, Aimee J Karstens, Jennifer R Geske, Julie A Fields, Jason Hassenstab, Christopher G Schwarz, Nirubol Tosakulwong, Heather J Wiste, Clifford R Jack, Kejal Kantarci, and Michelle M Mielke

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Essential functions of MLL1 and MLL2 in retinal development and cone cell maintenance, Chi Sun, Xiaodong Zhang, Philip A Ruzycki, and Shiming Chen

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Isolation of SARS-CoV-2 in viral cell culture in immunocompromised patients with persistently positive RT-PCR results, Abby Sung, Adam L Bailey, Henry B Stewart, David McDonald, Meghan A Wallace, Kate Peacock, Candace Miller, Kimberly A Reske, Caroline A O'Neil, Victoria J Fraser, Michael S Diamond, Carey-Ann D Burnham, Hilary M Babcock, and Jennie H Kwon

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Tumor-associated macrophages in multiple myeloma: Advances in biology and therapy, Jennifer Sun, Chaelee Park, Nicole Guenthner, Shannon Gurley, Luna Zhang, Berit Lubben, Ola Adebayo, Hannah Bash, Yixuan Chen, Mina Maksimos, Barbara Muz, and Abdel Kareem Azab

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Fracture healing is delayed in the absence of gasdermin-interleukin-1 signaling, Kai Sun, Chun Wang, Jianqiu Xiao, Michael D. Brodt, Luorongxin Yuan, Tong Yang, Yael Alippe, Huimin Hu, Dingjun Hao, Yousef Abu-Amer, Matthew J. Silva, Jie Shen, and Gabriel Mbalaviele

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Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors, Clara Sze Man Tang, Mimmi Mononen, Wai-Yee Lam, Sheng Chih Jin, Xuehan Zhuang, Maria-Mercè Garcia-Barcelo, Qiongfen Lin, Yujia Yang, Makoto Sahara, Elif Eroglu, Kenneth R. Chien, Haifa Hong, Paul Kwong Hang Tam, and Peter J. Gruber

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Safety and efficacy of mass drug administration with a single-dose triple-drug regimen of albendazole + diethylcarbamazine + ivermectin for lymphatic filariasis in Papua New Guinea: An open-label, cluster-randomised trial, Livingstone Tavul, Kobie O'Brian, Gary J. Weil, Charles W. Goss, and et al

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Safety and efficacy of pembrolizumab in combination with acalabrutinib in advanced head and neck squamous cell carcinoma: Phase 2 proof-of-concept study, Matthew H Taylor, Courtney B Betts, Lauren Maloney, Eric Nadler, Alain Algazi, Michael J Guarino, John Nemunaitis, Antonio Jimeno, Priti Patel, Veerendra Munugalavadla, Lin Tao, Douglas Adkins, Jerome H Goldschmidt, Ezra E W Cohen, and Lisa M Coussens

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Maternal obesogenic diet enhances cholestatic liver disease in offspring, Michael D Thompson, Holly Hinrichs, Austin Faerber, Phillip I Tarr, and Nicholas O Davidson

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SORL1 polymorphisms in Mexican patients with Alzheimer's disease, Danira Toral-Rios, Elizabeth Ruiz-Sánchez, Nancy Lucero Martínez Rodríguez, Marlene Maury-Rosillo, Óscar Rosas-Carrasco, Fernando Becerril-Pérez, Francisco Mena-Barranco, Rosa Carvajal-García, Daniela Silva-Adaya, Yair Delgado-Namorado, Gerardo Ramos-Palacios, Carmen Sánchez-Torres, and Victoria Campos-Peña

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Establishment of novel neuroendocrine carcinoma patient-derived xenograft models for receptor peptide-targeted therapy, Catherine G Tran, Jacqueline L Mudd, Ramaswamy Govindan, Paul F Cliften, and Ryan C Fields

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Association of multidimensional poverty with dementia in adults aged 50 years or older in South Africa, Jean-Francois Trani, Jacqueline Moodley, May Thu Thu Maw, and Ganesh M. Babulal

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Dysregulation of the leukocyte signaling landscape during acute COVID-19, Isaiah R. Turnbull, Anja Fuchs, Kenneth E. Remy, Michael P. Kelly, Elfaridah P. Frazier, Sarbani Ghosh, Shin-Wen Chang, Monty B. Mazer, Annie Hess, Jennifer M. Leonard, Mark H. Hoofnagle, Marco Colonna, and Richard S. Hotchkiss

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Identification of gut bacteria such as Lactobacillus johnsonii that disseminate to systemic tissues of wild type and MyD88-/- mice, Sreeram Udayan, Panagiota Stamou, Fiona Crispie, Ana Hickey, Alexandria N Floyd, Chyi-Song Hsieh, Paul D Cotter, Orla O'Sullivan, Silvia Melgar, Paul W O'Toole, Rodney D Newberry, Valerio Rossini, and Ken Nally

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Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium, Jacob A. Van Winkle, Stefan T. Peterson, Elizabeth A. Kennedy, Michael J. Wheadon, Harshad Ingle, Chandni Desai, Rachel Rodgers, David A. Constant, Austin P. Wright, Lena Li, Maxim N. Artyomov, Sanghyun Lee, Megan T. Baldridge, and Timothy J. Nice

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Hereditary alpha-tryptasemia modifies clinical phenotypes among individuals with congenital hypermobility disorders, Maribel Vazquez, Jack Chovanec, Jiwon Kim, Thomas DiMaggio, Joshua D Milner, Clair A Francomano, Christina A Gurnett, Marco Ritelli, Marina Colombi, and Jonathan J Lyons

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Cisplatin resistance can be curtailed by blunting BNIP3-mediated mitochondrial autophagy, Caterina Vianello, Gerald W Dorn 2nd, and et al

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Electrocochleography and cognition are important predictors of speech perception outcomes in noise for cochlear implant recipients, Amit Walia, Matthew A Shew, Dorina Kallogjeri, Cameron C Wick, Nedim Durakovic, Shannon M Lefler, Amanda J Ortmann, Jacques A Herzog, and Craig A Buchman

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m6A modifications regulate intestinal immunity and rotavirus infection, Anmin Wang, Gaopeng Hou, Siyuan Ding, and et al

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Baseline microglial activation correlates with brain amyloidosis and longitudinal cognitive decline in Alzheimer disease, Qing Wang, Gengsheng Chen, Suzanne E Schindler, Jon Christensen, Nicole S McKay, Jingxia Liu, Sicheng Wang, Zhexian Sun, Jason Hassenstab, Shaney Flores, Russ Hornbeck, Lisa Cash, Carlos Cruchaga, Anne M Fagan, Zhude Tu, John C Morris, Yong Wang, Tammie L S Benzinger, and et al

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SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation, Songyan Wang, Cliff J Luke, Stephen C Pak, Victoria Shi, Liyun Chen, Jonathan Moore, Arlise P Andress, Kay Jayachandran, Jin Zhang, Yi Huang, Marina Platik, Anthony A Apicelli, Julie K Schwarz, Perry W Grigsby, Gary A Silverman, and Stephanie Markovina

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Cryo-EM analysis of Ebola virus nucleocapsid-like assembly, Yan Wang, Jennifer M Binning, Grigore D Pintilie, Wah Chiu, Gaya K Amarasinghe, Daisy W Leung, and Zhaoming Su

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Computational genomics in the era of precision medicine: Applications to variant analysis and gene therapy, Yung-Chun Wang, Julie Choi, Shujuan Zhao, Mariam Khanfar, Kuangying Yang, Po-Ying Fu, Max Wrubel, Xiaobing Yu, Sheng Chih Jin, and et al

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High-dimensional analysis reveals distinct endotypes in patients with idiopathic inflammatory myopathies, Erin M Wilfong, Todd Bartkowiak, Katherine N Vowell, Camille S Westlake, Jonathan M Irish, Peggy L Kendall, Leslie J Crofford, and Rachel H Bonami

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Incidence of emergency department visits for electric rental scooters using detailed ridership data, Chelsea Williams, Cindy C Bitter, Steven Lorber, Caleb R Overfelt, Holly Zehfus, Andrea Spangler, Valerie Lew, Lawrence M Lewis, and Rosanne S Naunheim

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Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer, Andrew J Wilson, Vijayalaxmi G Gupta, Qi Liu, Fiona Yull, Marta A Crispens, and Dineo Khabele

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Naturalistic driving measures of route selection associate with resting state networks in older adults, Julie K Wisch, Catherine M Roe, Ganesh M Babulal, Nicholas Metcalf, Ann M Johnson, Samantha Murphy, Jamie Hicks, Jason M Doherty, John C Morris, and Beau M Ances

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NIA Long Life Family Study: Objectives, design, and heritability of cross-sectional and longitudinal phenotypes, Mary K. Wojczynski, Shiow Jiuan Lin, Paola Sebastiani, Thomas T. Perls, Joseph Lee, Alexander Kulminski, Anne Newman, Joe M. Zmuda, Kaare Christensen, and Michael A. Province

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A diffusion MRI-based spatiotemporal continuum of the embryonic mouse brain for probing gene-neuroanatomy connections, Dan Wu, Linda J Richards, Zhiyong Zhao, Zuozhen Cao, Wanrong Luo, Wei Shao, Song-Hai Shi, Michael I Miller, Susumu Mori, Seth Blackshaw, and Jiangyang Zhang

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Machine learning-based scoring models to predict hematopoietic stem cell mobilization in allogeneic donors, Jingyu Xiang, Min Shi, Mark A Fiala, Feng Gao, Michael P Rettig, Geoffrey L Uy, Mark A Schroeder, Katherine N Weilbaecher, Keith E Stockerl-Goldstein, Shamim Mollah, and John F DiPersio

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Risks of mental health outcomes in people with covid-19: Cohort study, Yan Xie, Evan Xu, and Ziyad Al-Aly

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Long-term cardiovascular outcomes of COVID-19, Yan Xie, Evan Xu, Benjamin Bowe, and Ziyad Al-Aly

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Spatiotemporal expression of regulatory kinases directs the transition from mitosis to cellular morphogenesis in Drosophila, Shuo Yang, Jennifer McAdow, Yingqiu Du, Jennifer Trigg, Paul H Taghert, and Aaron N Johnson

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The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling, Hannah Yan, Forrest C Walker, Arushana Ali, Hyojeong Han, Lin Tan, Lucas Veillon, Philip L Lorenzi, Megan T Baldridge, and Katherine Y King

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Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci, Xianyong Yin, Adam E Locke, Erica Young, Liron Ganel, Indraniel Das, Haley Abel, Nathan O Stitziel, and et al

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A somatic mutation in moesin drives progression into acute myeloid leukemia, Ouyang Yuan and Jeffrey A Magee

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Estimated population access to acute stroke and telestroke centers in the US, 2019, Kori S. Zachrison, Rebecca E. Cash, Opeolu Adeoye, Krislyn M. Boggs, Lee H. Schwamm, Ateev Mehrotra, and Carlos A. Camargo

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SARS-CoV-2 spreads through cell-to-cell transmission, Cong Zeng, John P Evans, Tiffany King, Yi-Min Zheng, Eugene M Oltz, Sean P J Whelan, Linda J Saif, Mark E Peeples, and Shan-Lu Liu

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Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract, Jianan Zhang, Morgan E. Walker, Katherine Z. Sanidad, Hongna Zhang, Michael B. Major, Dennis Goldfarb, and et al

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DANSR: A tool for the detection of annotated and novel small RNAs, Jin Zhang, Abdallah M Eteleeb, Emily B Rozycki, Matthew J Inkman, Amy Ly, Russell E Scharf, Kay Jayachandran, Bradley A Krasnick, Thomas Mazur, Nicole M White, Ryan C Fields, and Christopher A Maher

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Mining imaging and clinical data with machine learning approaches for the diagnosis and early detection of Parkinson's disease, Jing Zhang

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Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism, Yiming Zhang, Cassandra B Higgins, Brian A Van Tine, John S Bomalaski, and Brian J DeBosch

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Targeting fatty acid β-oxidation impairs monocyte differentiation and prolongs heart allograft survival, Yuehui Zhu, Hao Dun, Li Ye, Yuriko Terada, Leah P. Shriver, Gary J. Patti, Daniel Kreisel, Andrew E. Gelman, and Brian W. Wong

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An evidence-based definition of anemia for singleton, uncomplicated pregnancies, Amanda C. Zofkie, W. Holt Garner, Rachel C. Schell, Alexandra S. Ragsdale, Donald D. McIntire, Scott W. Roberts, and Catherine Y. Spong

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Therapeutic drug monitoring in perianal fistulizing Crohn's disease, Mir Zulqarnain, Parakkal Deepak, and Andres J Yarur

Submissions from 2021

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Global PARITY: Study design for a multi-centered, international point prevalence study to estimate the burden of pediatric acute critical illness in resource-limited settings, Qalab Abbas, Kenneth E Remy, and et al

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Protocol for DRAUP: A deimplementation programme to decrease routine chest radiographs after central venous catheter insertion, Enyo Ablordeppey, Byron Powell, Virginia McKay, Shannon Keating, Aimee James, Christopher Carpenter, Marin Kollef, and Richard Griffey

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Acaricidal activity of Foeniculum vulgare against Rhipicephalus annulatus is mainly dependent on its constituent from trans-anethone, Shawky M. Aboelhadid, Waleed M. Arafa, Abdel-Azeem S. Abdel-Baki, Atalay Sokmen, Saleh Al-Quraishy, Ahmed O. Hassan, and Asmaa A. Kamel

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The role of mental imagery in Parkinson's disease rehabilitation, Amit Abraham, Ryan P Duncan, and Gammon M Earhart

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A phase Ib/IIa clinical trial of dantrolene sodium in patients with Wolfram syndrome, Damien Abreu, Stephen I. Stone, Toni S. Pearson, Robert C. Bucelli, Ashley N. Simpson, Stacy Hurst, Cris M. Brown, Kelly Kries, Chinyere Onwumere, Hongjie Gu, James Hoekel, Lawrence Tychsen, Gregory P. Van Stavern, Neil H. White, Bess A. Marshall, Tamara Hershey, and Fumihiko Urano