The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2017

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Exploitation of a newly-identified entry pathway into the malaria parasite-infected erythrocyte to inhibit parasite egress, Svetlana Glushakova, Brad L. Busse, Matthias Garten, Josh R. Beck, Rick M. Fairhurst, Daniel E. Goldberg, and Joshua Zimmerberg

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A double-blind, randomized, comparative study of the use of a combination of uridine triphosphate trisodium, cytidine monophosphate disodium, and hydroxocobalamin, versus isolated treatment with hydroxocobalamin, in patients presenting with compressive neuralgias, Henrique Goldberg, Marco Antonio Mibielli, Carlos Pereira Nunes, Stephanie Wrobel Goldberg, Luiz Buchman, Spyros GE Mezitis, Helio Rzetelna, Lisa Oliveria, Mauro Geller, and Fernanda Wajnsztajn

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Variability in antifungal and antiviral use in hospitalized children, Jennifer L. Goldman, Rachael K. Ross, Brian R. Lee, Jason G. Newland, Adam L. Hersh, Matthew P. Kronman, and Jeffrey S. Gerber

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Lineage A betacoronavirus NS2 proteins and the homologous torovirus Berne pp1a carboxy-terminal domain are phosphodiesterases that antagonize activation of RNase L, Stephen A. Goldstein, Joshua M. Thornbrough, Rong Zhang, Babal K. Jha, Yize Li, Ruth Elliott, Katherine Quiroz-Figueroa, Annie I. Chen, Robert H. Silverman, and Susan R. Weiss

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1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function, Felicia Gomez, Mary F. Feitosa, and et al

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Recent positive selection in genes of the mammalian epidermal differentiation complex locus, Zane A. Goodwin and Cristina de Guzman Strong

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A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis, Leslie Goo, Laura A. VanBlargan, Kimberly A. Dowd, Michael S. Diamond, and Theodore C. Pierson

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Fructose in breast milk is positively associated with infant body composition at 6 months of age, Michael I. Goran, Ashley A. Martin, Tanya L. Alderete, Hideji Fujiwara, and David A. Fields

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Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects, Jennifer Govero, Michael S. Diamond, and et al

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Phase I dose-escalation studies of roniciclib, a pan-cyclin-dependent kinase inhibitor, in advanced malignancies, Ramaswamy Govindan and et al

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Actin/myosin-V- and activity-dependent inter-synaptic vesicle exchange in central neurons, Michael W. Gramlich and Vitaly A. Klyachko

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Phenotypic and molecular characterisation of CDK13-related congenital heart defects, dysmorphic facial features and intellectual developmental disorders, Dorothy K. Grange, Marisa V. Andrews, and et al

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A postnatal role for embryonic myosin revealed by MYH3 mutations that alter TGFβ signaling and cause autosomal dominant spondylocarpotarsal synostosis, Dorothy K. Grange and et al

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Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly, Tina Graves-Lindsay, Derek Albracht, Robert S. Fulton, Milinn Kremitzki, Vincent Magrini, Chris Markovic, Sean McGrath, Karyn Meltz Steinberg, Richard K. Wilson, and et al

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Lipidomic evaluation of feline neurologic disease after AAV gene therapy, Heather L. Gray-Edwards, Xuntian Jiang, Ashley N. Randle, Amanda R. Taylor, Taylor L. Voss, Aime K. Johnson, Victoria J. McCurdy, Miguel Sena-Esteves, Daniel S. Ory, and Douglas R. Martin

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Lipidomic evaluation of feline neurologic disease after AAV gene therapy, Heather L. Gray-Edwards, Xuntian Jiang, Ashley N. Randle, Amanda R. Taylor, Taylor L. Voss, Aime K. Johnson, Victoria J. McCurdy, Miguel Sena-Esteves, Daniel S. Ory, and Douglas R. Martin

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Brain structure in pediatric Tourette syndrome, D. J. Greene, A. C. Williams III, J. M. Koller, B. L. Schlaggar, K. J. Black, and The Tourette Association of America Neuroimaging Consortium

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Targeting dendritic cells to accelerate T-cell activation overcomes a bottleneck in tuberculosis vaccine efficacy, Kristin L. Griffiths, Mushtaq Ahmed, Shibali Das, Radha Gopal, William Horne, Terry D. Connell, Kelly D. Moynihan, Jay K. Kolls, Darrell J. Irvine, Maxim N. Artyomov, Javier Rangel-Moreno, and Shabaana A. Khader

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A classification algorithm for predicting progression from normal cognition to mild cognitive impairment across five cohorts: The preclinical AD consortium, Alden L. Gross, Jason J. Hassenstab, Sterling C. Johnson, Lindsay R. Clark, Susan M. Resnick, Melissa Kitner-Triolo, Colin L. Masters, Paul Maruff, John C. Morris, Anja Soldan, Corinne Pettigrew, and Marilyn S. Albert

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Declines in prevalence of adolescent substance use disorders and delinquent behaviors in the USA: A unitary trend?, R. A. Grucza, R. F. Krueger, Arpana Agrawal, A. D. Plunk, M. J. Krauss, J. Bongu, P. A. Cavazos-Rehg, and L. J. Bierut

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Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming, Adilson Guilherme, David J. Pedersen, Elizabeth Henchey, Felipe S. Henriques, Laura V. Danai, Yuefei Shen, Batuhan Yenilmez, DaeYoung Jung, Jason K. Kim, Irfan J. Lodhi, Clay F. Semenkovich, and Michael P. Czech

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Draft genome sequence of a Salmonella enterica serovar Typhi strain resistant to fourth-generation cephalosporin and fluoroquinolone antibiotics, Danish Gul, Robert F. Potter, Hurmat Riaz, Shifa Tariq Ashraf, Meghan A. Wallace, Tehmina Munir, Amjad Ali, Carey-Ann Burnham, Gautam Dantas, and Saadia Andleeb

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In vivo two-photon imaging of astrocytes in GFAP-GFP transgenic mice, Dongjun Guo, Jia Zou, Nicholas Rensing, and Michael Wong

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Rapamycin attenuates acute seizure-induced astrocyte injury in mice in vivo, Dongjun Guo, Jia Zou, and Michael Wong

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Genetic metabolic complementation establishes a requirement for GDP-fucose in Leishmania, Hongjie Guo, Natalia M. Novozhilova, Giulia Bandini, Salvatore J. Turco, Michael A. J. Ferguson, and Stephen M. Beverly

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TGF-â1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells, Pin Guo, Yanan Yu, Huanting Li, Daoxiang Zhang, Anjing Gong, Shifang Li, Wei Liu, Lei Cheng, Yongming Qiu, Weicheng Yao, Luo Li, and Yugong Feng

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Polarity of varicosity initiation in central neuron mechanosensation, Yuanzheng Gu, Peter Jukkola, Qian Wang, Thomas Esparza, Yi Zhao, David Brody, and Chen Gu

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Pulmonary fibrosis requires cell-autonomous mesenchymal fibroblast growth factor (FGF) signaling, Robert D. Guzy, Ling Li, Craig Smith, Samuel J. Dorry, Hyun Young Koo, Lin Chen, and David M. Ornitz

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Toxoplasma effectors targeting host signaling and transcription, Mohamed-Ali Hakimi, Philipp Olias, and L. David Sibley

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Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries, Carmen M. Halabi, Thomas J. Broekelmann, Michelle Lin, Vivian S. Lee, Mon-Li Chu, and Robert P. Mecham

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ChREBP refines the hepatic response to fructose to protect the liver from injury, Angela M. Hall and Brian N. Finck

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RNA and proteins: Mutual respect [version 1; referees: 3 approved], Kathleen B. Hall

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A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance, Babette C. Hammerling, Rita H. Najor, Melissa Q. Cortez, Sarah E. Shires, Leonardo J. Leon, Eileen R. Gonzalez, Daniela Boassa, Sébastien Phan, Andrea Thor, Rebecca E. Jimenez, Hong Li, Richard N. Kitsis, Gerald W. Dorn II, Junichi Sadoshima, Mark H. Ellisman, and Åsa B. Gustafsson

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Randomized, open-label, phase 1/2a study to determine the maximum tolerated dose of intraventricular sustained release nimodipine for subarachnoid hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]), Daniel Hanggi, Nima Etminan, Francois Aldrich, Hans Jakob Steiger, Stephen A. Mayer, Michael N. Diringer, Brian L. Hoh, J Mocco, Herbert J. Faleck, R. Loch Macdonald, and Newton Investigators

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Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems, Christian M. Harding, Marina R. Pulido, Gisela Di Venanzio, Rachel L. Kinsella, Andrew I. Webb, Nichollas E. Scott, Jeronimo Pachon, and Mario F. Feldman

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Anthropometric discriminators of type 2 diabetes among White and Black American adults, Dale S. Hardy, Devita T. Stallings, Jane T. Garvin, Francine C. Gachupin, Hongyan Xu, and Susan B. Racette

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Best anthropometric discriminators of incident type 2 diabetes among white and black adults: A longitudinal ARIC study, Dale S. Hardy, Devita T. Stallings, Jane T. Garvin, Hongyan Xu, and Susan B. Racette

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Amyloid β–associated cognitive decline in the absence of clinical disease progression and systemic illness, Karra D. Harrington, Yen Ying Lim, David Ames, Jason Hassenstab, Simon M. Laws, Ralph N. Martins, Stephanie Rainey-Smith, Joanne Robertson, Christopher C. Rowe, Olivier Salvado, Vincent Dore, Victor L. Villemagne, Peter J. Snyder, Colin L. Masters, and Paul Maruff

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Which comorbid conditions should we be analyzing as risk factors for healthcare-associated infections?, Anthony D. Harris, Lisa Pineles, Deverick Anderson, Keith F. Woeltje, William E. Trick, Keith S. Kaye, Deborah S. Yokoe, Ann-Christine Nyquist, David P. Calfee, and Surbhi Leekha

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Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators, Kathryn M. Hart, Katelyn E. Moeder, Chris M. W. Ho, Maxwell I. Zimmerman, Thomas E. Frederick, and Gregory R. Bowman

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A human antibody against Zika virus crosslinks the E protein to prevent infection, S. Saif Hasan, Andrew Miller, Gopal Sapparapu, Estefania Fernandez, Thomas Klose, Feng Long, Andrei Fokine, Jason C. Porta, Wen Jiang, Michael S. Diamond, James E. Crowe Jr., Richard J. Kuhn, and Michael G. Rossmann

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The Targeted SMAC Mimetic SW IV-134 is a strong enhancer of standard chemotherapy in pancreatic cancer, Yassar M. Hashim, Suwanna Vangveravong, Narendra V. Sankpal, Pratibha S. Binder, Jingxia Liu, S. Peter Goedegebuure, Robert H. Mach, Dirk Spitzer, and William G. Hawkins

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Multiparametric MRI and [18F]fluorodeoxyglucose positron emission tomography imaging is a potential prognostic imaging biomarker in recurrent glioblastoma, Comron Hassanzadeh, Yuan James Rao, Anupama Chundury, Jackson Rowe, Maria Rosana Ponisio, Akash Sharma, Michelle Miller-Thomas, Christina I. Tsien, and Joseph E. Ippolito

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TAM receptors are not required for Zika virus infection in mice, Andrew K. Hastings, Laura J. Yockey, Brett W. Jagger, Jesse Hwang, Ryuta Uraki, Hallie F. Gaitsch, Lindsay A. Parnell, Bin Cao, Indira U. Mysorekar, Carla V. Rothlin, Erol Fikrig, Michael S. Diamond, and Akiko Iwasaki

Electrophysiological sequelae of hemispherotomy in ipsilateral human cortex, Ammar H. Hawasli, Ravi Chacko, Nicholas P. Szrama, David T. Bundy, Mrinal Pahwa, Chester K. Yarbrough, Brian J. Dlouhy, David D. Limbrick, Dennis L. Barbour, Matthew D. Smyth, and Eric C. Leuthardt

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Pretreatment cognitive and neural differences between sapropterin dihydrochloride responders and non-responders with phenylketonuria, Zoe Hawks, Joshua Shimony, Jerrel Rutlin, Dorothy K. Grange, Shawn E. Christ, and Desiree A. White

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Mutations in the E2 glycoprotein and the 3' untranslated region enhance chikungunya virus virulence in mice, David W. Hawman, Kathryn S. Carpentier, Julie M. Fox, Nicholas A. May, Wes Sanders, Stephanie A. Montgomery, Nathaniel J. Moorman, Michael S. Diamond, and Thomas E. Morrison

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Improved survival after acute graft-versus-host disease diagnosis in the modern era, Robert J. Hayashi, Ravi Vig, and et al.

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Computational assessment of potassium and magnesium ion binding to a buried pocket in GTPase-associating center RNA, Hamed S. Hayatshahi, Daniel R. Roe, Rodrigo Galindo-Murillo, Kathleen B. Hall, and Thomas E. Chetham III

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Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli, Tracy H. Hazen, Jane Michalski, Qingwei Luo, Amol C. Shetty, Sean C. Daugherty, James M. Fleckenstein, and David A. Rasko

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Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli, Tracy H. Hazen, Jane Michalski, Qingwei Luo, Amol C. Shetty, Sean C. Daugherty, James M. Fleckenstein, and David A. Rasko

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Genetic effects influencing risk for major depressive disorder in China and Europe, A. C. Heath, J. P. Rice, and et al

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Progression of Fatty Muscle Degeneration in Atraumatic Rotator Cuff Tears, Jonah Hebert-Davies, Sharlene A. Teefey, Karen Steger-May, Aaron M. Chamberlain, William Middleton, Kathryn Robinson, Ken Yamaguchi, and Jay D. Keener

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Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth, Guangxu He, Yu Shi, Joohyun Lim, Teresita Bellido, Jiangdong Ni, and Fanxin Long

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Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry, Jason M. Held, Shin-Cheng Tzeng, and et al

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Acute knockdown of Kv4.1 regulates repetitive firing rates and clock gene expression in the suprachiasmatic nucleus and daily rhythms in locomotor behavior, Tracy O. Hermanstyne, Daniel Granados-Fuentes, Rebecca L. Mellor, Erik D. Herzog, and Jeanne M. Nerbonne

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The electrically evoked compound action potential: From laboratory to clinic, Shuman He, Holly F.B. Teagle, and Craig A. Buchman

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Use of low-dose computed tomography to assess pulmonary tuberculosis among healthcare workers in a tuberculosis hospital, Wei He, Bu-Dong Chen, Yan Lv, Zhen Zhou, Jin-Ping Xu, Ping-Xin Lv, Xin-Hua Zhou, Feng-Gang Ning, Cheng-Hai Li, Dong-Po Wang, and Jie Zheng

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Whole genome analysis of a schistosomiasis-transmitting freshwater snail, LaDeana W. Hillier, Patrick Minx, Sandra Clifton, Catrina Fronick, Lucinda Fulton, Vince Magrini, Chad Tomlinson, Richard K. Wilson, and et al

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Human perception of electrical stimulation on the surface of somatosensory cortex, Shivayogi V. Hiremath, Elizabeth C. Tyler-Kabara, Jesse J. Wheeler, Daniel W. Moran, Robert A. Gaunt, Jennifer L. Collinger, Stephen T. Foldes, Douglas J. Weber, Weidong Chen, Michael L. Boninger, and Wei Wang

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The role of mucosal immunity in the pathogenesis of necrotizing enterocolitis, Zerina Hodzic, Alexa M. Bolock, and Misty Good

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Altered sleep and EEG power in the P301S Tau transgenic mouse model, Jerrah K. Holth, Thomas E. Mahan, Grace O. Robinson, Andreia Rocha, and David M. Holtzman

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Multiplex shRNA screening of germ cell development by in vivo transfection of mouse testis, Nicholas R.Y. Ho, Abul R. Usmani, Yan Yin, Liang Ma, and Donald F. Conrad

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Fungal infections increase the mortality rate three-fold in necrotizing soft-tissue infections, Christopher B. Horn, Brendan M. Wesp, Nicholas B. Fiore, Rohit K. Rasane, Marlon Torres, Isaiah R. Turnbull, Obeid N. Ilahi, Laurie J. Punch, and Grant V. Bochicchio

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Splanchnic vein thrombosis in myeloproliferative neoplasms: Pathophysiology and molecular mechanisms of disease, Joan How, Amy Zhou, and Stephen T. Oh

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MicroRNA profiling reveals marker of motor neuron disease in ALS models, Mariah L. Hoye, Erica D. Koval, Amy J. Wegener, Theodore S. Hyman, Chengran Yang, David R. O'Brien, Rebecca L. Miller, Kathleen M. Schoch, Tao Shen, Tomonori Kunikata, David H. Gutmann, Joseph D. Dougherty, Timothy M. Miller, and et al

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Local processing in neurites of VGluT3- expressing amacrine cells differentially organizes visual information, Jen-Chun Hsiang, Keith P. Johnson, Linda Madisen, Hongkui Zeng, and Daniel Kerschensteiner

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The SWI/SNF protein PBRM1 restrains VHL-loss-driven clear cell renal cell carcinoma, James J. Hsieh and et al

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Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease, Brian Hsueh, Vanessa M. Burns, Philip Pauerstein, Katherine Holzem, Li Ye, Kristin Engberg, Ai-Chi Wang, Xueying Gu, Harini Chakravarthy, H. Efsun Arda, Gregory Charville, Hannes Vogel, Igor R. Efimov, Seung Kim, and Karl Deisseroth

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Effective antibiotic conservation by emergency antimicrobial stewardship during a drug shortage, Kevin Hsueh, Maria Reyes, Tamara Krekel, Ed Casabar, David J. Ritchie, S. Reza Jafarzadeh, Amanda J. Hays, Michael A. Lane, and Michael J. Durkin

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CEDNIK: Phenotypic and molecular characterization of an additional patient and review of the literature, Tina Hsu, Carrie C. Coughlin, Kristin G. Monaghan, Elise Fiala, Robert C. McKinstry, Alex R. Paciorkowski, and Marwan Shinawi

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Independent test of a model to predict severe acute esophagitis, Ellen X. Huang, Clifford G. Robinson, Alerson Molotievschi, Jeffrey D. Bradley, Joseph O. Deasy, and Jung Hun Oh

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Genome-wide screen for genes involved in Caenorhabditis elegans developmentally timed sleep, Huiyan Huang, Chen-Tseh Zhu, Lukas L. Skuja, Dustin J. Hayden, and Anne C. Hart

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Proteogenomic integration reveals therapeutic targets in breast cancer xenografts, Kuan-lin Huang, Shunqiang Li, Song Cao, Christopher Yoon, Matthew A. Wyczalkowski, Petra Erdmann-Gilmore, Jacqueline E. Snider, Jeremy Hoog, Beifang Niu, Zhanfang Guo, Sam Qiancheng Sun, Souzan Sanati, Adam Scott, Kai Ye, Michael D. McLellan, Michael C. Wendl, Jason M. Held, Sherri R. Davies, Cynthia Ma, R. Reid Townsend, Li Ding, and et al

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Cardiac lymphatic vessels, transport, and healing of the infarcted heart, Li-Hao Huang, Kory J. Lavine, and Gwendalyn J. Randolph

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cis-regulatory circuits regulating NEK6 kinase overexpression in transformed B cells Are super-enhancer independent, Yue Huang, Olivia I. Koues, Jiang-yang Zhao, Regina Liu, Sarah C. Pyfrom, Jacqueline E. Payton, and Eugene M. Oltz

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Two sisters with Mayer-Rokitansky-Küster-Hauser syndrome and serous adenocarcinoma of the ovary, Sarah P. Huepenbecker, Laura Divine, Christina S. Chu, and David G. Mutch

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Cell type-specific epigenomic analysis reveals a uniquely closed chormatin architecture in mouse rod photoreceptors, Andrew E. O. Hughes, Jennifer M. Enright, Connie A. Myers, Susan Q. Shen, and Joseph C. Corbo

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ExpressionDB: An open source platform for distributing genome-scale datasets, Laura D. Hughes, Scott A. Lewis, and Michael E. Hughes

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Determining the longitudinal validity and meaningful differences in HRQL of the PedsQL™ Sickle Cell Disease Module, Monica L. Hulbert and et al

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PRDM1 expression levels in marginal zone lymphoma and lymphoplasmacytic lymphoma, Mohammad Hussaini, Cecilia Yeung, Xiaopei Zhu, Abu-Sayeef Mirza, John Pfeifer, and Anjum Hassan

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Osteolipoma of the knee, Tien-Phat V. Huynh, Cara C. Cipriano, Ian S. Hagemann, and Michael V. Friedman

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Apolipoprotein E and Alzheimer’s disease: The influence of apolipoprotein E on amyloid- and other amyloidogenic proteins, Tien-Phat V. Huynh, Albert A. Davis, Jason D. Ulrich, and David M. Holtzman

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Gene expression in Leishmania is regulated predominantly by gene dosage, Stefano A. Iantorno, Caroline Durrant, Asis Khan, Mandy J. Sanders, Stephen M. Beverley, Wesley C. Warren, Matthew Berriman, David L. Sacks, James A. Cotton Wellcome Trust Sanger Institute, and Michael E. Grigg

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Aspergillus fumigatus copper export machinery and reactive oxygen intermediate defense counter host copper-mediated oxidative antimicrobial offense, Rachel A. Idol, Mary C. Dinauer, and et al

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The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help, Takeshi Inoue, Ryo Shinnakasu, Wataru Ise, Chie Kawai, Takeshi Egawa, and Tomohiro Kurosaki

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Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy, Akane Inoue-Yamauchi, Paul S. Jeng, Kwanghee Kim, Hui-Chen Chen, Song Han, Yogesh Tengarai Ganesan, Kota Ishizawa, Sylvia Jebiwott, Yiyu Dong, Maria C. Pietanza, Matthew D. Hellmann, Mark G. Kris, James J. Hsieh, and Emily H. Cheng

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Effectiveness of a triple-drug regimen for global elimination of lymphatic filariasis: A modelling study, Michael A. Irvine, Wilma A. Stolk, Morgan E. Smith, Swaminathan Subramanian, Brajendra K. Singh, Gary J. Weil, Edwin Michael, and T. Deirdre Hollingsworth

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A novel Rac1-GSPT1 signaling pathway controls astrogliosis following central nervous system injury, Taiji Ishii, Takehiko Ueyama, Michiko Shigyo, Masaaki Kohta, Takeshi Kondoh, Tomoharu Kuboyama, Tatsuya Uebi, Takeshi Hamada, David H. Gutmann, Atsu Aiba, Eiji Kohmura, Chihiro Tohda, and Naoaki Saito

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Esterase mutation is a mechanism of resistance to antimalarial compounds, Eva S. Istvan, Jeremy P. Mallari, Victoria C. Corey, Neekesh V. Dharia, Garland R. Marshall, Elizabeth A. Winzeler, and Daniel E. Goldberg

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Surgical site infection research opportunities, Kamal M. F. Itani, E. Patchen Dellinger, John Mazuski, Joseph Solomkin, George Allen, Joan C. Blanchard, Rachel Kelz, and Sandra I. Berrios-Torres

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Neuregulin and dopamine D4 receptors contribute independently to depotentiation of Schaffer collateral LTP by temperoammonic path stimulation, Yukitoshi Izumi and Charles F. Zorumski

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The effect of adding comorbidities to current centers for disease control and prevention central-line–associated bloodstream infection risk-adjustment methodology, Sarah S. Jackson, Surbhi Leekha, Laurence S. Magder, Lisa Pineles, Deverick J. Anderson, William E. Trick, Keith F. Woeltje, Keith S. Kaye, Kristen Stafford, Kerri Thom, Timothy J. Lowe, and Anthony D. Harris

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Potential molecular consequences of transgene integration: The R6/2 mouse example, Jessie C. Jacobsen, Serkan Erdin, Colby Chiang, Carrie Hanscom, Renee R. Handley, Douglas D. Barker, Alex Stortchevoi, Ian Blumenthal, Suzanne J. Reid, Russell G. Snell, Marcy E. MacDonald, A. Jennifer Morton, Carl Ernst, James F. Gusella, and Michael E. Talkowski

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Potential molecular consequences of transgene integration: The R6/2 mouse example, Jessie C. Jacobsen, Serken Erdin, Colby Chiang, Carrie Hanscom, Renee R. Handley, Douglas D. Barker, Alex Stortchevoi, Ian Blumenthal, Suzanne J. Reid, Russell G. Snell, Marcy E. MacDonald, A. Jennifer Morton, Carl Ernst, James F. Gusella, and Michael E. Talkowski

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A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage, Brett W. Jagger, Justin Richner, Michael S. Diamond, and et al

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Statoviruses, a novel taxon of RNA viruses present in the gastrointestinal tracts of diverse mammals, Andrew B. Janowski, Siddharth R. Krishnamurthy, Efrem S. Lim, Guoyan Zhao, Jason M. Brenchley, Dan H. Barouch, Chrissie Thakwalakwa, Mark J. Manary, Lori R. Holtz, and David Wang

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From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved], Andrew B. Janowski and Jason G. Newland

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Lack of MTTP activity in pluripotent stem cell-derived hepatocytes and cardiomyocytes abolishes apoB secretion and increases cell stress, Ali Javaheri and et al

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Prehypertensive blood pressures and regional cerebral blood flow independently relate to cognitive performance in midlife, J. Richard Jennings, Matthew F. Muldoon, Christopher Ryan, H. Michael Gach, Alicia Heim, Lei K. Sheu, and Peter J. Gianaros