The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2022

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Identification of novel mitochondrial pyruvate carrier inhibitors by homology modeling and pharmacophore-based virtual screening, Lamees Hegazy, Lauren Gill, Kelly Pyles, Christopher Kaiho, Sophia Kchouk, Brian Finck, Kyle McCommis, and Bahaa Elgendy

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SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase, Cassandra B Higgins, Allyson L Mayer, Yiming Zhang, Michael Franczyk, Samuel Ballentine, Jun Yoshino, and Brian J DeBosch

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Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice, Wesley T Hodges, Chaowapong Jarasvaraparn, Daniel Ferguson, Kristine Griffett, Lauren E Gill, Yana Chen, Ma Xenia G Ilagan, Lamees Hegazy, Bahaa Elgendy, Kevin Cho, Gary J Patti, Kyle S McCommis, and Brian N Finck

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Ultrasound-guided thrombin injection for the treatment of bleeding following kidney and liver biopsies, Mark J Hoegger and William D Middleton

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Comparison of bioelectrical impedance analysis with DXA in adolescents with cystic fibrosis before and after a resistance training intervention, Clifton J Holmes, Susan B Racette, Leslie Symonds, Ana Maria Arbeláez, Chao Cao, and Andrea Granados

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Feasibility and efficacy of telehealth-based resistance exercise training in adolescents with cystic fibrosis and glucose intolerance, Clifton J Holmes, Susan B Racette, Leslie Symonds, Ana Maria Arbeláez, Chao Cao, and Andrea Granados

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Protein kinase C (Pkc)-δ mediates arginine-induced glucagon secretion in pancreatic α-cells, Norikiyo Honzawa, Kei Fujimoto, Masaki Kobayashi, Daisuke Kohno, Osamu Kikuchi, Hiromi Yokota-Hashimoto, Eri Wada, Yuichi Ikeuchi, Yoko Tabei, Gerald W Dorn II, Kazunori Utsunomiya, Rimei Nishimura, and Tadahiro Kitamura

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A prospective, multicenter trial of a long-term bioabsorbable mesh with Sepra technology in cohort of challenging laparoscopic ventral or incisional hernia repairs (ATLAS trial), William W Hope, Jeffrey A Blatnik, and et al

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Movement through chemotherapy delay to initiation among breast cancer patients: A qualitative analysis, Ashley J Housten, Catalina Malinowski, Edna Paredes, Cassandra L Harris, Lorna H McNeill, and Mariana Chavez-MacGregor

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Preschool sleep and depression interact to predict gray matter volume trajectories across late childhood to adolescence, Caroline Hoyniak, Diana J Whalen, Rebecca Tillman, Joan L Luby, and Deanna M Barch

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A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C, Huiyan Huang, Jiehong Pan, Ariz Mohammad, Tao Huang, Anika G Lindsey, Hyori Kim, Jian Chen, Avinash Ramu, Stephanie A Morrison, Zachary D Dawson, Alex Z Hu, Eric Tycksen, Gary A Silverman, Dustin Baldridge, Jennifer A Wambach, Stephen C. Pak, Steven L Brody, Tim Schedl, and et al

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Transcriptomic profile investigations highlight a putative role for NUDT16 in sepsis, Susie Shih Yin Huang, Darawan Rinchai, Mohammed Toufiq, Basirudeen Syed Ahamed Kabeer, Jessica Roelands, Wouter Hendrickx, Sabri Boughorbel, Davide Bedognetti, Nicholas Van Panhuys, Damien Chaussabel, and Mathieu Garand

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A Bayesian network to predict the risk of post influenza vaccination Guillain-Barré syndrome: Development and validation study, Yun Huang, Chongliang Luo, Ying Jiang, Jingcheng Du, Cui Tao, Yong Chen, and Yuantao Hao

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Live-dead assay on unlabeled cells using phase imaging with computational specificity, Chenfei Hu, Shenghua He, Young Jae Lee, Yuchen He, Edward M Kong, Hua Li, Mark A Anastasio, and Gabriel Popescu

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Assessment of a plasma amyloid probability score to estimate amyloid positron emission tomography findings among adults with cognitive impairment, Yan Hu, Barry A. Siegel, David M. Holtzman, and et al

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The Geriatric Emergency Care Applied Research (GEAR) network approach: A protocol to advance stakeholder consensus and research priorities in geriatrics and dementia care in the emergency department, Ula Hwang, Christopher Carpenter, Scott Dresden, Jeffrey Dussetschleger, Angela Gifford, Ly Hoang, Jesseca Leggett, Armin Nowroozpoor, Zachary Taylor, Manish Shah, and The GEAR and GEAR 2.0 Networks

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Protocol for development of a core outcome set for clinical trials in melasma, Sarah Ibrahim, Bianca Kang, Daniel Schlessinger, Sarah Chiren, Jennifer Tang, Jamie Kirkham, Jochen Schmitt, Emily Poon, Ian Maher, Joseph Sobanko, Todd Cartee, and Murad Alam

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Persistent methicillin-susceptible bacteremia rapidly cleared with cefazolin and ertapenem combination therapy in a patient with COVID-19, Dan Ilges, Gayathri Krishnan, and Elvin Geng

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Multimodal thrombectomy device for treatment of acute deep venous thrombosis, Usama Ismail, Roger A Rowe, John Cashin, Guy M Genin, and Mohamed A Zayed

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Principles and applications of CRISPR toolkit in virus manipulation, diagnosis, and virus-host interactions, Saleh Jamehdor, Sara Pajouhanfar, Sadaf Saba, Georges Uzan, Ali Teimoori, and Sina Naserian

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Perceptions of risk of SARS-CoV-2 transmission in social and educational activities by infectious diseases and general pediatric healthcare providers, a pre-vaccine risk perception cross-sectional survey, Andrew B. Janowski, Philip M. Polgreen, Susan E. Beekmann, and Jason G. Newland

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Steroid hormone signaling activates thermal nociception during Drosophila peripheral nervous system development, Jacob S. Jaszczak, Laura DeVault, Lily Yeh Jan, and Yuh Nung Jan

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Laser interstitial thermal therapy in grade 2/3 IDH1/2 mutant gliomas: A preliminary report and literature review, Gabrielle W Johnson, Rowland H Han, Matthew D Smyth, Eric C Leuthardt, and Albert H Kim

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Understanding contributors to racial and ethnic inequities in COVID-19 incidence and mortality rates, Karen E. Joynt Maddox, Mat Reidhead, Joshua Grotzinger, Timothy McBride, Aaloke Mody, Elna Nagasako, Will Ross, Joseph T. Steensma, and Abigail R. Barker

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Integrin-mediated adhesion promotes centrosome separation in early mitosis, Siamak A Kamranvar, Deepesh Kumar Gupta, Anishia Wasberg, Liangwen Liu, Joan Roig, and Staffan Johansson

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Exploiting radiation induction of antigens in cancer: Targeted drug delivery, Vaishali Kapoor, Abhay K Singh, Calvin D Lewis, Sapna Deore, and Dennis E Hallahan

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Differences in shoulder internal rotation strength between baseball players with ulnar collateral ligament reconstruction and healthy controls, Sean Kennedy, Philip Sheedy, Brooks Klein, Mason Gist, Joseph Hannon, John Conway, Kalyssa Creed, and J. Craig Garrison

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Identification of kidney injury released circulating osteopontin as causal agent of respiratory failure, Fatima Zohra Khamissi, Liang Ning, Eirini Kefaloyianni, Hao Dun, Akshayakeerthi Arthanarisami, Amy Keller, Jeffrey J Atkinson, Wenjun Li, Brian Wong, Sabine Dietmann, Kory Lavine, Daniel Kreisel, and Andreas Herrlich

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Association of body mass index in midlife with morbidity burden in older adulthood and longevity, Sadiya S. Khan, Amy E. Krefman, Lihui Zhao, Lei Liu, Anna Chorniy, Martha L. Daviglus, Cuiping Schiman, Kiang Liu, Tina Shih, Daniel Garside, Thanh-Huyen T. Vu, Donald M. Lloyd-Jones, and Norrina B. Allen

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Oncology trainee perceptions of the prior authorization process: A national survey, Hyun Kim, Amar Srivastava, Prashant Gabani, Elizabeth Kim, Hohyun Lee, and Katrina S Pedersen

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Visually guided respiratory motion management for Ethos adaptive radiotherapy, Taeho Kim, Zhen Ji, Benjamin Lewis, Eric Laugeman, Alex Price, Yao Hao, Geoffrey Hugo, Nels Knutson, Bin Cai, Hyun Kim, and Lauren Henke

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Pevonedistat targets malignant cells in myeloproliferative neoplasms in vitro and in vivo via NFκB pathway inhibition, Tim Kong, Angelo B A Laranjeira, Taylor B Collins, Elisa S De Togni, Abigail J Wong, Mary C Fulbright, Marianna Ruzinova, Hamza Celik, Grant A Challen, Daniel A C Fisher, and Stephen T Oh

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Dear reviewers: Responses to common reviewer critiques about infant neuroimaging studies, Marta Korom, M Catalina Camacho, Courtney A Filippi, Roxane Licandro, Lucille A Moore, Alexander Dufford, Lilla Zöllei, Alice M Graham, Marisa Spann, Brittany Howell, FIT'NG, Sarah Shultz, and Dustin Scheinost

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Externalizing personality characteristics define clinically relevant subgroups of alcohol use disorder, Ildikó Kovács, Bernadett I Gál, Zsolt Horváth, Ildikó Demeter, Sándor Rózsa, Zoltán Janka, Róbert Urbán, Zsolt Demetrovics, and Bálint Andó

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Transcriptional profile and chromatin accessibility in zebrafish melanocytes and melanoma tumors, Eva Kramer, Paula Godoy, and Charles Kaufman

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A phase II trial of an alternative schedule of palbociclib and embedded serum TK1 analysis, Jairam Krishnamurthy, Jingqin Luo, Rama Suresh, Foluso Ademuyiwa, Caron Rigden, Timothy Rearden, Katherine Clifton, Katherine Weilbaecher, Ashley Frith, Anna Roshal, Mathew Cherian, Tracy Summa, Brittney Haas, Shana Thomas, Leonel Hernandez-Aya, Lindsey Peterson, Cynthia X Ma, and et al

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The role of whole blood transfusions in civilian trauma: A review of literature in military and civilian trauma, Shane Kronstedt, Joon Lee, David Millner, Connor Mattivi, Halli LaFrankie, Lorenzo Paladino, and Jeffrey Siegler

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It's getting complicated-A fresh look at p53-MDM2-ARF triangle in tumorigenesis and cancer therapy, Che-Pei Kung and Jason D Weber

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Serologic and cytokine signatures in children with multisystem inflammatory syndrome and coronavirus disease 2019, Stacey A. Lapp, Carol M. Kao, David A. Hunstad, and et al

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Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencing, Ninaad Lasrado, Nicholas Borcherding, Rajkumar Arumugam, Timothy K Starr, and Jay Reddy

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Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: Prospective observational study, Adam S Lauring, Hilary M Babcock, Jennie H Kwon, and et al

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Single-cell genomics for resolution of conserved bacterial genes and mobile genetic elements of the human intestinal microbiota using flow cytometry, Dylan Lawrence, Danielle E Campbell, Lawrence A Schriefer, Rachel Rodgers, Forrest C Walker, Marissa Turkin, Lindsay Droit, Miles Parkes, Scott A Handley, and Megan T Baldridge

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Clinical classification of symptomatic heterotopic pancreas of the stomach and duodenum: A case series and systematic literature review, Michael T. LeCompte, Brandon Mason, Keenan J. Robbins, Matoya Yano, Deyali Chatterjee, Ryan C. Fields, Steven M. Strasberg, and William G. Hawkins

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FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury, Bohm Lee, Yeonsoo Oh, Eunhye Cho, Aaron DiAntonio, Valeria Cavalli, Jung Eun Shin, Hae Woong Choi, and Yongcheol Cho

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Assessing infant cognition in field settings using eye-tracking: A pilot cohort trial in Sierra Leone, Jukka Leppänen, Julius Butcher, Claire Godbout, Kevin Stephenson, D. Taylor Hendrixson, Stacy Griswold, Beatrice Rogers, Patrick Webb, Aminata Koroma, and Mark Manary

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Evaluation of HIV treatment outcomes with reduced frequency of clinical encounters and antiretroviral treatment refills: A systematic review and meta-analysis, Noelle Le Tourneau, Ashley Germann, Ryan R. Thompson, Nathan Ford, Sheree Schwartz, Laura Beres, Aaloke Mody, Stefan Baral, Elvin H. Geng, and Ingrid Eshun-Wilson

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Patients with serious injection drug use-related infections who experience patient-directed discharges on oral antibiotics have high rates of antibiotic adherence but require multidisciplinary outpatient support for retention in care, Sophia Lewis, Stephen Y. Liang, Evan S. Schwarz, David B. Liss, Rachel P. Winograd, Nathanial S. Nolan, Michael J. Durkin, and Laura R. Marks

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Translational randomized phase II trial of cabozantinib in combination with nivolumab in advanced, recurrent, or metastatic endometrial cancer, Stephanie Lheureux, Carolyn McCourt, and et al

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Circadian pacemaker neurons display cophasic rhythms in basal calcium level and in fast calcium fluctuations, Xitong Liang, Timothy E Holy, and Paul H Taghert

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Current and future approaches to classify VUSs in LGMD-related genes, Chengcheng Li, Gabe Haller, and Conrad C Weihl

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Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation, Jing Li, Tripti Kumari, Andrew Barazia, Vishwanath Jha, Si-Yeon Jeong, Amber Olson, Mijeong Kim, Bum-Kyu Lee, Vijayprakash Manickam, Zhimin Song, Regina Clemens, Babak Razani, Jonghwan Kim, Mary C Dinauer, and Jaehyung Cho

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Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN, Yihang Li, Maria F. Pazyra-Murphy, Daina Avizonis, Mariana de Sá Tavares Russo, Sophia Tang, Chiung-Ya Chen, Yi-Ping Hsueh, Johann S. Bergholz, Tao Jiang, Jean J. Zhao, Jian Zhu, Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio, and Rosalind A. Segal

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Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN, Yihang Li, Maria F. Pazyra-Murphy, Daina Avizonis, Mariana de Sá Tavares Russo, Sophia Tang, Chiung-Ya Chen, Yi-Ping Hsueh, Johann S. Bergholz, Tao Jiang, Jean J. Zhao, Jian Zhu, Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio, and Rosalind A. Segal

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The ASCC2 CUE domain in the ALKBH3-ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin, Patrick M Lombardi, Timur Rusanov, Rebecca Rodell, Nima Mosammaparast, and et al

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Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins, Cliff J Luke, Stephanie Markovina, Misty Good, Ira E Wight, Brian J Thomas, John M Linneman, Wyatt E Lanik, Olga Koroleva, Maggie R Coffman, Mark T Miedel, Qingqing Gong, Arlise Andress, Marlene Campos Guerrero, Songyan Wang, LiYun Chen, Wandy L Beatty, Kelsey N Hausmann, Frances V White, James A J Fitzpatrick, Anthony Orvedahl, Stephen C Pak, and Gary A Silverman

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ODACH: A One-shot Distributed Algorithm for Cox model with heterogeneous multi-center data, Chongliang Luo, Rui Duan, Adam C Naj, Henry R Kranzler, Jiang Bian, and Yong Chen

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DLMM as a lossless one-shot algorithm for collaborative multi-site distributed linear mixed models, Chongliang Luo and et al

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Parent-of-origin effects propagate through networks to shape metabolic traits, Juan F. Macias-Velasco, Celine L. St Pierre, Jessica P. Wayhart, Li Yin, Larry Spears, Mario A. Miranda, Caryn Carson, Katsuhiko Funai, James M. Cheverud, Clay F. Semenkovich, and Heather A. Lawson

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Spherical Nucleic Acids as precision therapeutics for the treatment of cancer—From bench to bedside, Akanksha S Mahajan and Alexander H Stegh

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Use of statins for the prevention of cardiovascular disease in 41 low-income and middle-income countries: A cross-sectional study of nationally representative, individual-level data, Maja E Marcus, Mark D Huffman, and et al

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First-generation and continuing-generation college graduates' application, acceptance, and matriculation to U.S. medical schools: A national cohort study, Hyacinth R C Mason, Ashar Ata, Mytien Nguyen, Sunny Nakae, Devasmita Chakraverty, Branden Eggan, Sarah Martinez, and Donna B Jeffe

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Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification, Shailendra Maurya, Wei Yang, Minori Tamai, Qiang Zhang, Petra Erdmann-Gilmore, Amelia Bystry, Fernanda Martins Rodrigues, Mark C Valentine, Wing H Wong, Reid Townsend, and Todd E Druley

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TRAF2, an innate immune sensor, reciprocally regulates mitophagy and inflammation to maintain cardiac myocyte homeostasis, Xiucui Ma, David R Rawnsley, Attila Kovacs, Moydul Islam, John T Murphy, Chen Zhao, Minu Kumari, Layla Foroughi, Haiyan Liu, Kevin Qi, Aaradhya Diwan, Krzysztof Hyrc, Sarah Evans, Takashi Satoh, Brent A French, Kenneth B Margulies, Ali Javaheri, Babak Razani, Douglas L Mann, Kartik Mani, and Abhinav Diwan

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Assessing the relationship of patient reported outcome measures with functional status in dysferlinopathy: A Rasch analysis approach, Anna G Mayhew, Catherine Siener, Alan Pestronk, and et al

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One-carbon metabolism in children with marasmus and kwashiorkor, Thaddaeus May, Bethany de la Haye, Gabrielle Nord, Kevin Klatt, Kevin Stephenson, Sara Adams, Lucy Bollinger, Neil Hanchard, Erland Arning, Teodoro Bottiglieri, Kenneth Maleta, Mark Manary, and Farook Jahoor

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The immunoregulatory landscape of human tuberculosis granulomas, Erin F. McCaffrey, Shabaana A. Khader, and et al

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Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden, Celia A McKee, Jiyeon Lee, Yuqi Cai, Takashi Saito, Takaomi Saido, and Erik S Musiek

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LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint, Wilson McKerrow, Xuya Wang, Carlos Mendez-Dorantes, Paolo Mita, Song Cao, Mark Grivainis, Li Ding, John LaCava, Kathleen H Burns, Jef D Boeke, and David Fenyö

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Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1, Karla E Merz, Jinhee Hwang, Chunxue Zhou, Rajakrishnan Veluthakal, Erika M McCown, Angelica Hamilton, Eunjin Oh, Wenting Dai, Patrick T Fueger, Lei Jiang, Janice M Huss, and Debbie C Thurmond

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Oncogenic Kras-mediated cytokine CCL15 regulates pancreatic cancer cell migration and invasion through ROS, Justin K Messex, Kiyah L A Adams, William G Hawkins, David DeNardo, Nabeel Bardeesy, Daniel D Billadeau, and Geou-Yarh Liou

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Analysis and classification of postcatheterization femoral arteriovenous fistulas based on color Doppler examinations, William D Middleton and Kathryn A Robinson

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Quantifying regional α -synuclein, amyloid β, and tau accumulation in Lewy body dementia, Rebecca L Miller, Dhruva D Dhavale, Jennifer Y O'Shea, Kristin M Andruska, Jialu Liu, Erin E Franklin, Chandana Buddhala, Susan K Loftin, John R Cirrito, Richard J Perrin, Nigel J Cairns, Meghan C Campbell, Joel S Perlmutter, and Paul T Kotzbauer

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β Cell function and plasma insulin clearance in people with obesity and different glycemic status, Bettina Mittendorfer, Bruce W Patterson, Gordon I Smith, Mihoko Yoshino, and Samuel Klein

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Neural signatures of data-driven psychopathology dimensions at the transition to adolescence, Amirhossein Modabbernia, Giorgia Michelini, Abraham Reichenberg, Roman Kotov, Deanna Barch, and Sophia Frangou

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Coronavirus disease 2019 (COVID-19) research agenda for healthcare epidemiology, Lona Mody, Hilary M Babcock, Jennie H Kwon, and et al

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Contralateral limb specificity for movement preparation in the parietal reach region, Eric Mooshagian, Eric A. Yttri, Arthur D. Loewy, and Lawrence H. Snyder

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The history and innovations of blood vessel anastomosis, William R Moritz, Shreya Raman, Sydney Pessin, Cameron Martin, Xiaowei Li, Amanda Westman, and Justin M Sacks

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Prevalence, mechanisms, and return to sport after isolated popliteus injuries in athletes: A systematic review, Caellagh Morrissey and Derrick Knapik

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Resting state functional connectivity provides mechanistic predictions of future changes in sedentary behavior, Timothy P Morris, Aaron Kucyi, Sheeba Arnold Anteraper, Maiya Rachel Geddes, Alfonso Nieto-Castañon, Agnieszka Burzynska, Neha P Gothe, Jason Fanning, Elizabeth A Salerno, Susan Whitfield-Gabrieli, Charles H Hillman, Edward McAuley, and Arthur F Kramer

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Advances and gaps in SARS-CoV-2 infection models, César Muñoz-Fontela, Michael S. Diamond, and et al

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'I need time to start antiretroviral therapy': Understanding reasons for delayed ART initiation among people diagnosed with HIV in Lusaka, Zambia, Chanda Mwamba, Laura K Beres, Stephanie M Topp, Njekwa Mukamba, Sandra Simbeza, Kombatende Sikombe, Aaloke Mody, Elvin Geng, Charles B Holmes, Caitlin E Kennedy, Izukanji Sikazwe, Julie A Denison, and Carolyn Bolton Moore

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Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential, Tetsushi Nakao, C Charles Gu, Lisa de Las Fuentes, and et al

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Antibiotic therapy and risk of early-onset colorectal cancer: A national case-control study, Long H Nguyen, Yin Cao, Nurgul Batyrbekova, Bjorn Roelstraete, Wenjie Ma, Hamed Khalili, Mingyang Song, Andrew T Chan, and Jonas F Ludvigsson

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What can Brinley plots tell us about cognitive aging? Exploring simulated data and modified Brinley plots, Jessica Nicosia, Emily R Cohen-Shikora, and Michael J Strube

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Treatment patterns and outcomes following disease progression on anti-PD-1 therapies for advanced melanoma, Beth L. Nordstrom, Melissa Hamilton, Jenna M. Collins, Dennis Earle, Ying Zhang, Shivani Srivastava, and Leonel Hernandez-Aya

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Quantifying rural disparity in healthcare utilization in the United States: Analysis of a large midwestern healthcare system, Akua Nuako, Jingxia Liu, Giang Pham, Nina Smock, Aimee James, Timothy Baker, Laura Bierut, Graham Colditz, and Li-Shiun Chen

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Segmental colitis associated with diverticulosis masquerading as polyploid-appearing mucosa in the rectosigmoid area on endoscopy and as focal thickening on imaging, Eugene C. Nwankwo, Gebran Khneizer, Gregory Sayuk, Jill Elwing, Necat Havlioglu, and Michael Presti

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NanoLuc reporters identify COL4A5 nonsense mutations susceptible to drug-induced stop codon readthrough, Kohei Omachi, Hirofumi Kai, Michel Roberge, and Jeffrey H Miner

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Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma, Michael D Onken, Sarah E Noda, Kevin M Kaltenbronn, Cheryl Frankfater, Carol M Makepeace, Nikki Fettig, Kisha D Piggott, Philip L Custer, Joseph E Ippolito, and Kendall J Blumer

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Apparent sunk cost effect in rational agents, Torben Ott, Paul Masset, Thiago S Gouvêa, and Adam Kepecs

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Sonobiopsy for minimally invasive, spatiotemporally-controlled, and sensitive detection of glioblastoma-derived circulating tumor DNA, Christopher Pacia, Jinyun Yuan, Yimei Yue, Lu Xu, Arash Nazeri, Rupen Desai, H. Michael Gach, Xiaowei Wang, Michael Talcott, Aadel Chaudhuri, Gavin Dunn, Eric Leuthardt, and Hong Chen

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Gastric organoids: Progress and remaining challenges, Min-Jiao Pang, Joseph R Burclaff, Ramon Jin, Mahliyah Adkins-Threats, Luciana H Osaki, Yunan Han, Jason C Mills, Zhi-Feng Miao, and Zhen-Ning Wang

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Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate, Arpan Parichha, Varun Suresh, Mallika Chatterjee, Aditya Kshirsagar, Lihi Ben-Reuven, Tsviya Olender, M Mark Taketo, Velena Radosevic, Mihaela Bobic-Rasonja, Sara Trnski, Michael J Holtzman, Nataša Jovanov-Milosevic, Orly Reiner, and Shubha Tole

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Association between workplace absenteeism and alcohol use disorder from the National Survey on Drug Use and Health, 2015-2019, Ian C. Parsley, Ann Marie Dale, Sherri L. Fisher, Carrie M. Mintz, Sarah M. Hartz, Bradley A. Evanoff, and Laura J. Bierut

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Increased connectivity among sensory and motor regions during visual and audiovisual speech perception, Jonathan E. Peelle, Brent Spehar, Michael S. Jones, Sarah McConkey, Joel Myerson, Sandra Hale, Mitchell S. Sommers, and Nancy Tye-Murray

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Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617, Lei Peng, Yingxia Hu, Madeleine C Mankowski, Ping Ren, Rita E Chen, Michael S Diamond, and et al

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Genetic and transcriptional contributions to relapse in normal karyotype acute myeloid leukemia, Allegra A Petti, Saad M Khan, Ziheng Xu, Nichole Helton, Catrina C Fronick, Robert Fulton, Sai M Ramakrishnan, Sridhar Nonavinkere Srivatsan, Sharon E Heath, Peter Westervelt, Jacqueline E Payton, Matthew J Walter, Daniel C Link, John DiPersio, Christopher Miller, and Timothy J Ley

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Utility of using electrocardiogram measures of heart rate variability as a measure of cardiovascular autonomic neuropathy in type 1 diabetes patients, Rodica Pop-Busui, Jye-Yu C Backlund, Ionut Bebu, Barbara H Braffett, Gayle Lorenzi, Neil H White, John M Lachin, Elsayed Z Soliman, and DCCT/EDIC Research Group

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EML1 is essential for retinal photoreceptor migration and survival, Deepak Poria, Chi Sun, Andrea Santeford, Michel Kielar, Rajendra S Apte, Oleg G Kisselev, Shimming Chen, and Vladimir J Kefalov

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Dose-finding study of ibrutinib and venetoclax in relapsed or refractory mantle cell lymphoma, Craig A Portell, Nolan A Wages, Brad S Kahl, Lihua E Budde, Robert W Chen, Jonathon B Cohen, Nikole E Varhegyi, Gina R Petroni, and Michael E Williams