The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2017

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Novel SOX17 frameshift mutations in endometrial cancer are functionally distinct from recurrent missense mutations., Christopher J. Walker, Matthew J. O'Hern, Vanida A. Serna, Takeshi Kurita, Mario A. Miranda, Caroline E. Sapp, David G. Mutch, David E. Cohn, and Paul J. Goodfellow

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Scalable production of iPSC-derived human neurons to identify tau-lowering compounds by high-content screening, Chao Wang, Michael E. Ward, Robert Chen, Kai Liu, Tara E. Tracy, Xu Chen, Min Xie, Peter Dongmin Sohn, Connor Ludwig, Anke Meyer-Franke, Celeste M. Karch, Sheng Ding, and Li Gan

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Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells, Chun Wang, Can-Xin Xu, Yael Alippe, Chao Qu, Jianqiu Xiao, Ernestina Schipani, Roberto Civitelli, Yousef Abu-Amer, and Gabriel Mbalaviele

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PMP22 exon 4 deletion causes ER retention of PMP22 and a gain-of-function allele in CMT1E, David S. Wang, Xingyao Wu, Yunhong Bai, Craig Zaidman, Tiffany Grider, John Kamholz, James R. Lupski, Anne M. Connolly, and Michael E. Shy

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Conformational changes at cytoplasmic intersubunit interactions control Kir channel gating, Shizhen Wang, William F. Borschel, Sarah Heyman, Phillip Hsu, and Colin G. Nichols

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Empirical comparison of diffusion kurtosis imaging and diffusion basis spectrum imaging using the same acquisition in healthy young adults, Sijia Wang, Daniel J. Peterson, Yong Wang, Qing Wang, Thomas J. Grabowski, Wenbin Li, and Tara M. Madhyastha

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Template-dependent multiple displacement amplification for profiling human circulating RNA, Weihua Wang, Yi Ren, Yang Lu, Yuan Xu, Seth D. Crosby, Adrian M. Di Bisceglie, and Xiaofeng Fan

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The aromatic amino acid hydroxylase genes AAH1 and AAH2 in Toxoplasma gondii contribute to transmission in the cat, Zi T. Wang, Shiv K. Verma, Jitender P. Dubey, and L. David Sibley

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Clinicopathology and treatment of a giant malignant phyllodes tumor of the breast: A case report and literature review, Wayne A. Warner, Vandana Devika Sookdeo, Maurice Fortune, Meenakshi Akhilesh, Chalapathi Rao Adidam Venkata, Wayne Mohammed, Cassandra Ramkissoon, Dave Harnanan, Lemuel Pran, and Ravi Maharaj

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Rare nodular malignant melanoma of the heel in the Caribbean: A case report, Wayne A. Warner, Vandana Devika Sookdeo, Srikanth Umakanthan, Kevin Sarran, Lemuel Pran, Maurice Fortune, Wesley Greaves, Sharda Narinesingh, Dave Harnanan, and Ravi Maharaj

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The nuclear receptor HIZR-1 uses zinc as a ligand to mediate homeostasis in response to high zinc, Kurt Warnhoff, Hyun C. Roh, Zuzana Kocsisova, Chieh-Hsiang Tan, Andrew Morrison, Damari Croswell, Daniel L. Schneider, and Kerry Kornfeld

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A new chicken genome assembly provides insight into avian genome structure, Wesley C. Warren, LaDeana W. Hillier, Chad Tomlinson, Patrick Minx, Milinn Kremitzki, Tina Graves, Chris Markovic, and et al

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Inhibiting plasma kallikrein for hereditary angioedema prophylaxis, H. J. Wedner and et al

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A systematic exploration of the interactions between bacterial effector proteins and host cell membranes, Bethany A. Weigele, Robert C. Orchard, Alyssa Jimenez, Gregory W. Cox, and Neal M. Alto

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Similarities and differences of functional connectivity in drug-naïve, first-episode adolescent and young adult with major depressive disorder and schizophrenia, Shengnan Wei, Fay Womer, Haiyang Geng, Xiaowei Jiang, Qian Zhou, Miao Chang, Yifang Zhou, Yanqing Tang, and Fei Wang

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A stable but reversible integrated surrogate reporter for assaying CRISPR/Cas9-stimulated homology-directed repair, Yahong Wen, Grace Liao, Thomas Pritchard, Ting-Ting Zhao, Jon P. Connelly, Shondra M. Pruett-Miller, Valerie Blanc, Nicholas O. Davidson, and Blair B. Madison

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Accelerated return to sport after osteochondral autograft plug transfer, Brian C. Werner, Chris T. Cosgrove, C. Jan Gilmore, Matthew L. Lyons, Mark D. Miller, Stephen F. Brockmeier, and David R. Diduch

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Multi-institutional analysis shows that low PCAT-14 expression associates with poor outcomes in prostate cancer, Nicole M. White, Shuang G. Zhao, Jin Zhang, Emily B. Rozycki, Ha X. Dang, Sandra D. McFadden, Abdallah M. Eteleeb, Mohammed Alshalalfa, Ismael A. Vergara, Nicholas Erho, Jeffrey M. Arbeit, Robert Jeffrey Karnes, Robert B. Den, Elai Davicioni, and Christopher A. Maher

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Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents Staphylococcal enterotoxin B pathology, Sarah J.C. Whitfield, Chris Taylor, Jane E. Risdall, Gareth D. Griffiths, James T.A. Jones, E. Diane Williamson, Sjoerd Rijpkema, Luisa Saraiva, Sandrine Vessillier, A. Christopher Green, and Alun J. Carter

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Proxies for success: How the application process correlates to PhD pursuit for a small diversity research program, Dawayne Whittington, Latricia E. Wallace, and Cherilynn R. Shadding

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Diversity of amyloid-beta proteoforms in the Alzheimer’s disease brain, Norelle C. Wildburger, Thomas J. Esparza, Richard D. LeDuc, Ryan T. Fellers, Paul M. Thomas, Nigel J. Cairns, Neil L. Kelleher, Randall J. Bateman, and David L. Brody

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Follow-up of prostatectomy versus observation for early prostate cancer, Timothy J. Wilt, Karen M. Jones, Michael J. Barry, Gerald L. Andriole, Daniel Culkin, Thomas Wheeler, William J. Aronson, and Michael K. Brawer

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Fast label-free multilayered histology-like imaging of human breast cancer by photoacoustic microscopy, Terence T.W. Wong, Ruiying Zhang, Pengfei Hai, Chi Zhang, Miguel A. Pleitez, Rebecca L. Aft, Deborah V. Novack, and Lihong V. Wang

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Biodistribution and PET Imaging of pharmacokinetics of manganese in mice using Manganese-52, A. Lake Wooten, Tolulope A. Aweda, Benjamin C. Lewis, Rebecca B. Gross, and Suzanne E. Lapi

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The Mycobacterium tuberculosis MmpL11 cell wall lipid transporter is important for biofilm formation, intracellular growth, and nonreplicating persistence, Catherine C. Wright, Fong Fu Hsu, Eusondia Arnett, Jennifer L. Dunaj, Patrick M. Davidson, Sophia A. Pacheco, Melanie J. Harriff, David M. Lewinsohn, Larry S. Schlesinger, and Georgiana E. Purdy

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Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair, Chia-Lung Wu, Kelly A. Kimmerling, Dianne Little, and Farshid Guilak

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Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma, Megan Wu, Jennifer Guan, Chris Li, Simon Gunter, Labeeba Nusrat, Sheena Ng, Karan Dhand, Cindi Morshead, Albert Kim, and Sunit Das

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Genome sequence of enterovirus D68 from St. Louis, Missouri, USA, 2016, Kristine M. Wylie, Todd N. Wylie, and Gregory A. Storch

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Dorsal-CA1 hippocampal neuronal ensembles encode nicotine-reward contextual associations, Li Xia, Stephanie K. Nygard, Gabe G. Sobczak, Nicholas J. Hourguettes, and Michael R. Bruchas

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Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury, Yan Xie, Benjamin Bowe, Tingting Li, Hong Xian, Yan Yan, and Ziyad Al-Aly

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Risk of death among users of Proton Pump Inhibitors: A longitudinal observational cohort study of United States veterans, Yan Xie, Benjamin Bowe, Tingting Li, Hong Xian, Yan Yan, and Ziyad Al-Aly

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Cd36 knockout mice are protected against lithogenic diet-induced gallstones, Yan Xie, Vincenza Cifarelli, Terri Pietka, Elizabeth P. Newberry, Susan M. Kennedy, Amin Khalifeh-Soltani, Robin Clugston, Kamran Atabai, Nada A. Abumrad, and Nicholas O. Davidson

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Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer’s disease, Chengjie Xiong, Tammie Benzinger, Virginia Buckles, Randall J. Bateman, and et al

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ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation, Can-Xin Xu, Tae-Jin Lee, Nagisa Sakurai, Karen Krchma, Fang Liu, Daofeng Li, Ting Wang, and Kyunghee Choi

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The role of retinol dehydrogenase 10 in the cone visual cycle, Yunlu Xue, Shinya Sato, David Razafsky, Bhubanananda Sahu, Susan Q. Shen, Chloe Potter, Lisa L. Sandell, Joseph C. Corbo, Krzysztof Palczewski, Akiko Maeda, Didier Hodzic, and Vladimir J. Kefalov

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β-n-oxalyl-l-α, β -diaminopropionic acid (β -odap) content in lathyrus sativus: The integration of nitrogen and sulfur metabolism through β -cyanoalanine synthase, Quanle Xu, Fengjuan Liu, Peng Chen, Joseph M. Jez, and Hari B. Krishnan

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Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis, Wei Xu, Priya Luthra, Chao Wu, Jyoti Batra, Daisy W. Leung, Christopher F. Basler, and Gaya K. Amarasinghe

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Overcoming the roadblocks to cardiac cell therapy using tissue engineering, Mounica Yanamandala, Wuqiang Zhu, Daniel J. Garry, Timothy J. Kamp, Joshua M. Hare, Ho-wook Jun, Young-sup Yoon, Nenad Bursac, Sumanth D. Prabhu, Gerald W. Dorn II, Roberto Bolli, and Jianyi Zhang

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Work-related correlates of occupational sitting in a diverse sample of employees in Midwest metropolitan cities, Lin Yang, J. Aaron Hipp, Jung Ae Lee, Rachel G. Tabak, Elizabeth A. Dodson, Christine M. Marx, and Ross C. Brownson

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Leisure-time physical activity and circulating 25-hydroxyvitamin D levels in cancer survivors: A cross-sectional analysis using data from the US National Health and Nutrition Examination Survey, Lin Yang and Adetunji T. Toriola

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Phospholipase Cγ1 (PLCγ1) controls osteoclast numbers via colony-stimulating factor 1 (CSF-1)-dependent diacylglycerol/β-catenin/cyclinD1 pathway, Zhengfeng Yang, Seokho Kim, Sahil Mahajan, Ali Zamani, and Roberta Faccio

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The Brief Case: Bacteremia and vertebral osteomyelitis due to Staphylococcus schleiferi, Melanie L. Yarbrough, Yasir Hamad, Carey-Ann D. Burnham, and Ige A. George

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Alzheimer's disease pathology and shunt surgery outcome in normal pressure hydrocephalus, Sevil Yasar, Ignacio Jusue-Torres, Jennifer Lu, Jamie Robinson, Mira A. Patel, Barbara Crain, Kathryn A. Carson, Jamie Hoffberger, Sachin Batra, Eric Sankey, Abhay Moghekar, and Daniele Rigamonti

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The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome, Jason J. Yi, Smita R. Paranjape, Matthew P. Walker, Rajarshi Choudhury, Justin M. Wolter, Giulia Fragola, Michael J. Emanuele, Michael B. Major, and Mark J. Zylka

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Intra- and inter-individual variability of microRNA levels in human cerebrospinal fluid: Critical implications for biomarker discovery, Hyejin Yoon, Krystal C. Belmonte, Tom Kasten, Randall Bateman, and Jungsu Kim

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Intra- and inter-individual variability of microRNA levels in human cerebrospinal fluid: Critical implications for biomarker discovery, Hyejin Yoon, Krystal C. Belmonte, Tom Kasten, Randall Bateman, and Jungsu Kim

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Management of intracranial melanomas in the era of precision medicine, Grace J. Young, Wenya Linda Bi, Winona W. Wu, Tanner M. Johanns, Gavin P. Dunn, and Ian F. Dunn

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Repeating platinum/bevacizumab in recurrent or progressive cervical cancer yields marginal survival benefits, Abigail S. Zamorano, Leping Wan, Matthew A. Powell, and L. Stewart Massad

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Complementary network-based approaches for exploring genetic structure and functional connectivity in two vulnerable, endemic ground squirrels, Victoria H. Zero, Adi Barocas, Denim M. Jochimsen, Agnes Pelletier, Xavier Giroux-Bougard, Daryl R. Trumbo, Jessica A. Castillo, Diane Evans Mack, Mark A. Linnell, Rachel M. Pigg, Jessica Hoisington-Lopez, Stephen F. Spear, Melanie A. Murphy, and Lisette P. Waits

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Uncovering the transcriptomic and epigenomic landscape of nicotinic receptor genes in non-neuronal tissues, Bo Zhang, Pamela Madden, Junchen Gu, Xiaoyun Xing, Savita Sankar, Jennifer Flynn, Kristen Kroll, and Ting Wang

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Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels, Guohui Zhang, Yanyan Geng, Yakang Jin, Jingyi Shi, Kelli McFarland, Karl L. Magleby, Lawrence Salkoff, and Jianmin Cui

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Acute CD47 blockade during ischemic myocardial reperfusion enhances phagocytosis-associated cardiac repair, Shuang Zhang, Xin-Yi Yeap, Matthew DeBerge, Nivedita K. Naresh, Kevin Wang, Zhengxin Jiang, Jane E. Wilcox, Steven M. White, John P. Morrow, Paul W. Burridge, Daniel Procissi, Evan A. Scott, William Frazier, and Edward B. Thorp

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Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American, Tian-Xiao Zhang, Nancy L. Saccone, Laura J. Bierut, and John P. Rice

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A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment, Haiyong Zhao and Kyunghee Choi

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Two forms of death in ageing Caenorhabditis elegans, Yuan Zhao, Ann F. Gilliat, Matthias Ziehm, Mark Turmaine, Hongyuan Wang, Marina Ezcurra, Chenhao Yang, George Phillips, David McBay, William B. Zhang, Linda Partridge, Zachary Pincus, and David Gems

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Cell-free measurements of brightness of fluorescently labeled antibodies, Haiying Zhou, George Tourkakis, Dennis Shi, David M. Kim, Hairong Zhang, Tommy Du, William C. Eades, and Mikhail Y. Berezin

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Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation, Jia Zhou, Renee L. Sears, Xiaoyun Xing, Bo Zhang, Daofeng Li, Nicole B. Rockweiler, Hyo Sik Jang, Mayank N.K. Choudhary, Hyung Joo Lee, Rebecca F. Lowdon, Jason Arand, Brianne Tabers, C. Charles Gu, Theodore J. Cicero, and Ting Wang

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Threading the biophysics of mammalian Slo1 channels onto structures of an invertebrate Slo1 channel, Yu Zhou, Huanghe Yang, Jianmin Cui, and Christopher J. Lingle

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Mechanisms of noncovalent β subunit regulation of NaV channel gating, Wandi Zhu, Taylor L. Voelker, Zoltan Varga, Angela R. Schubert, Jeanne M. Nerbonne, and Jonathan R. Silva

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Long-acting reversible contraception use among residents in obstetrics/gynecology training programs, Rachel E. Zigler, Jeffrey F. Peipert, Qiuhong Zhao, Ragini Maddipati, and Colleen McNicholas

Submissions from 2016

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Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation, Thiyagaragan M. Achariyar, Baoman Li, Weiguo Peng, Philip B. Verghese, Yang Shi, Evan McConnell, Abdellatif Benraiss, Tristan Kasper, Wei Song, Takahiro Takana, David Holtzman, Maiken Nedergaard, and Rashid Deane

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An ultrasensitive electrogenerated chemiluminescence-based immunoassay for specific detection of Zika virus, Dhiraj Acharya, Pradip Bastola, Linda Le, Amber M. Paul, Estefania Fernandez, Michael S. Diamond, and Wujian Miao

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Establishing the precise evolutionary history of a gene improves prediction of disease-causing missense mutations, Ogun Adebali, Alexander O. Reznik, Daniel S. Ory, and Igor B. Zhulin

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Ramucirumab with eribulin versus eribulin in locally recurrent or metastatic breast cancer previously treated with anthracycline and taxane therapy: A multicenter, randomized, phase II study, Foluso Ademuyiwa and et al

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Managing breast cancer in younger women: Challenges and solutions, Foluso O. Ademuyiwa, Amy Cyr, Jennifer Ivanovich, and Maria A. Thomas

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Adaptation and evaluation of the neighborhood environment walkability scale in India (NEWS-India), Deepti Adlakha, J. Aaron Hipp, and Ross C. Brownson

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Meta-analysis of genome-wide association studies for extraversion: Findings from the Genetics of Personality Consortium, Arpana Agrawal, Richard Grucza, Andrew C. Heath, Pamela A.F. Madden, Laura J. Bierut, and et al

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High-performance web services for querying gene and variant annotation, Benjamin J. Ainscough, Obi L. Griffith, and et al

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Neutrophil extracellular traps enhance early inflammatory response in Sendai virus-induced asthma phenotype, Antonina Akk, Luke E. Springer, and Christine T.N. Pham

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A Narnavirus in the trypanosomatid protist plant pathogen Phytomonas serpens, Natalia S. Akopyants, Lon-Fye Lye, Deborah E. Dobson, Julius Lukes, and Stephen M. Beverley

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A novel bunyavirus-like virus of trypanosomatid protist parasites, Natalia S. Akopyants, Lon-Fye Lye, Deborah E. Dobson, Julius Lukes, and Stephen M. Beverley

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Anxious/depressed symptoms are related to microstructural maturation of white matter in typically developing youths, Matthew D. Albaugh, Simon Ducharme, Sherif Karama, Richard Watts, John D. Lewis, Catherine Orr, Tuong-Vi Nguyen, Robert C. McKinstry, Kelly N. Botteron, Alan C. Evans, James J. Hudziak, and The Brain Development Cooperative Group

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A sign on CT that predicts a hazardous ureteral anomaly, E. S. Allam, D. Y. Johnson, S. G. Grewal, and F. E. Johnson

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Morphological assessment of the retina in uveitis, Michael M. Altaweel, Sapna S. Gangaputra, Jennifer E. Thorne, James P. Dunn, Susan G. Elner, Glenn J. Jaffe, Rosa Y. Kim, P. Kumar Rao, Susan B. Reed, John H. Kempen, and MUST Research Group

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GenSeed-HMM: A tool for progressive assembly using profile HMMs as seeds and its application in Alpavirinae viral discovery from metagenomic data, João M.P. Alves, Andre L. de Oliveira, Tatiana O.M. Sandberg, Jaime L. Moreno-Gallego, Marcelo A.F. de Toledo, Elisabeth M.M. de Moura, Liliane S. Oliveira, Alan M. Durham, Dolores U. Mehnert, Paolo M. de A. Zanotto, Alejandro Reyes, and Arthur Gruber

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Video capsule endoscopy in left ventricular assist device recipients with obscure gastrointestinal bleeding, Surachai Amornsawadwattana, Michael Nassif, David Raymer, Shane LaRue, and Chien-Huan Chen

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RNA-Seq of the Caribbean reef-building coral Orbicella faveolata (Scleractinia-Merulinidae) under bleaching and disease stress expands models of coral innate immunity, David A. Anderson, Marcus E. Walz, Ernesto Weil, Peter Tonellato, and Matthew C. Smith

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Predictors of full-time faculty appointment among MD-PhD program graduates: A national cohort study, Dorothy A. Andriole and Donna B. Jeffe

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General framework for meta-analysis of haplotype association tests, Ping An, Ingrid B. Borecki, Michael A. Province, and et al

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Treatment with Tumor-Treating Fields therapy and pulse dose bevacizumab in patients with bevacizumab-refractory recurrent glioblastoma: A case series., George Ansstas and David D. Tran

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Diffusion tensor imaging with direct cytopathological validation: Characterisation of decorin treatment in experimental juvenile communicating hydrocephalus, Anuriti Aojula, Hannah Botfield, James Patterson McAllister II, Ana Maria Gonzalez, Osama Abdullah, Ann Logan, and Alexandra Sinclair

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Characteristics of illegal and legal cigarette packs sold in Guatemala, Rodrigo Arevalo, Juan E. Corral, Diego Monzon, Mira Yoon, and Joaquin Barnoya

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Evaluation of an immunochromatographic assay for rapid detection of penicillin-binding protein 2a in human and animal Staphylococcus intermedius group, Staphylococcus lugdunensis, and Staphylococcus schleiferi clinical isolate, A. R. Arnold, Carey-Ann Burnham, B. A. Ford, S. D. Lawhon, S. K. McAllister, D Lonsway, V. Albrecht, R. C. Jerris, J. K. Rasheed, B. Limbago, E. M. Burd, and L. F. Westblade

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Racial and ethnic heterogeneity in self-reported diabetes prevalence trends across Hispanic subgroups, National Health Interview Survey, 1997–2012, Cassandra Arroyo-Johnson, Krista D. Mincey, Nicole Ackermann, Laurel Milam, Melody S. Goodman, and Graham A. Colditz

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Vortex ring behavior provides the epigenetic blueprint for the human heart, Per M. Arvidsson, Sándor J. Kovács, Johannes Töger, Rasmus Borgquist, Einar Heiberg, Marcus Carlsson, and Håkan Arheden

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Maternal fructose drives placental uric acid production leading to adverse fetal outcomes, Zeenat A. Asghar, Alysha Thompson, Maggie Chi, Andrew Cusumano, Suzanne Scheaffer, Noor Al-Hammadi, Jessica L. Saben, and Kelle H. Moley

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Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)*, Jason W. Ashley, William D. Hancock, Alexander J. Nelson, Robert N. Bone, Hubert M. Tse, Mary Wohltmann, John Turk, and Sasanka Ramanadham

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Combinatorial strategies based on CRAd-IL24 and CRAd-ING4 virotherapy with anti-angiogenesis treatment for ovarian cancer, Ahmad Mohammad Ashshi, Adel Galal El-Shemi, Igor P. Dmitriev, Elena A. Kashentseva, and David T. Curiel

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Esophageal squamous cell cancer in a highly endemic region, Akwi W. Asombang, Violet Kayamba, Mpala M. Lisulo, Kathryn Trinkaus, Victor Mudenda, Edford Sinkala, Stayner Mwanamakondo, Themba Banda, Rose Soko, and Paul Kelly

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Exploring the physiological correlates of chronic mild traumatic brain injury symptoms, Serguei V. Astafiev, Kristina L. Zinn, Gordon L. Shulman, and Maurizio Corbetta

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Implantable loop recorder monitoring for refining management of children with inherited arrhythmia syndromes, Jennifer N. Avari Silva, Burt I. Bromberg, Fredrick K. Emge, Tammy M. Bowman, and George F. Van Hare

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The targetable epigenetic tumor protein EZH2 is enriched in intraocular medulloepithelioma, Sarah E. Avedschmidt, Anna M. Stagner, Ralph C. Eagle Jr., George J. Harocopos, Yali Dou, and Rajesh C. Rao

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MR imaging–derived oxygen-hemoglobin dissociation curves and fetal-placental oxygen-hemoglobin affinities, Reut Avni, Ofra Golani, Ayelet Akselrod-Ballin, Yonni Cohen, Inbal Biton, Joel R. Garbow, and Michael Neeman

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A critical evaluation of the Down syndrome diagnosis for LB1, type specimen of Homo floresiensis, Karen L. Baab, Peter Brown, Dean Falk, Joan T. Richtsmeier, Charles F. Hildebolt, Kirk Smith, and William Jungers

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Development and interval testing of a naturalistic driving methodology to evaluate driving behavior in clinical research [version 2; referees: 2 approved], Ganesh M. Babulal, Aaron Addison, Nupur Ghoshal, Sarah H. Stout, Elizabeth K. Vernon, Mark Sellan, and Catherine M. Roe

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Creating a driving profile for older adults using GPS devices and naturalistic driving methodology, Ganesh M. Babulal, Cindy M. Traub, Mollie Webb, Sarah H. Stout, Aaron Addison, David B. Carr, Brian R. Ott, John C. Morris, and Catherine M. Roe

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Rab3-GEF controls active zone development at the Drosophila neuromuscular junction, Haneui Bae, Shirui Chen, John P. Roche, Minrong Ai, Chunlai Wu, Aaron Diantonio, and Ethan R. Graf

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Human central nervous system (CNS) ApoE isoforms are increased by age, differentially altered by amyloidosis, and relative amounts reversed in the CNS compared with plasma, Alaina T. Baker-Nigh, Kwasi G. Mawuenyega, James G. Bollinger, Vitaliy Ovod, Tom Kasten, Erin E. Franklin, Fan Liao, Hong Jiang, David Holtzman, Nigel J. Cairns, John C. Morris, and Randall J. Bateman

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Sterilization of lung matrices by supercritical carbon dioxide, Jenna L. Balestrini, Angela Liu, Ashley L. Gard, Janet Huie, Kelly M S Blatt, Jonas Schwan, Liping Zhao, Tom J. Broekelmann, Robert P. Mecham, Elise C. Wilcox, and Laura E. Niklason

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PER1 rs3027172 genotype interacts with early life stress to predict problematic alcohol use, but not reward-related ventral striatum activity, David A.A. Baranger, Chloe Ifrah, Aric A. Prather, Caitlin E. Carey, Nadia S. Corral-Frias, Emily Drabant Conley, Ahmad R. Hariri, and Ryan Bogdan