Submissions from 2014
The changing immune system in sepsis: Is individualized immuno-modulatory therapy the answer?, Jonathan S. Boomer, Jonathan M. Green, and Richard S. Hotchkiss
Dual transgene expression in murine cerebellar Purkinje neurons by viral transduction in vivo, Marie K. Bosch, Jeanne M. Nerbonne, and David M. Ornitz
Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus, Sandip K. Bose, Hangeun Kim, Keith Meyer, Nathan Wolins, Nicholas O. Davidson, and Ranjit Ray
Treatment of stage I lung cancer in high-risk and inoperable patients: SBRT vs. RFA vs. sublobar resection, Matthew J. Bott and Traves Crabtree
A new measure of fear of falling: psychometric properties of the fear of falling questionnaire revised (FFQ-R), Emily S. Bower, Julie L. Wetherell, C. C. Merz, Andrew J. Petkus, Vanessa L. Malcarne, and Eric J. Lenze
SkpA restrains synaptic terminal growth during development and promotes axonal degeneration following injury, E. J. Brace, Chunlai Wu, Vera Valakh, and Aaron DiAntonio
What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Han Jo Kim, Alexander R. Vaccaro, and Jeffrey C. Wang
Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis, Matthew R. Brier, Jewell B. Thomas, and Beau M. Ances
PDE7B is a novel, prognostically significant mediator of glioblastoma growth whose expression is regulated by endothelial cells, Michael D. Brooks, Erin Jackson, Nicole M. Warrington, Jingqin Luo, Jason T. Forys, Sara Taylor, Diane D. Mao, Jeffrey R. Leonard, Albert H. Kim, David Piwnica-Worms, Robi D. Mitra, and Joshua B. Rubin
Total knee arthroplasty after previous knee surgery, Robert H. Brophy, Benjamin L. Gray, Ryan M. Nunley, Robert L. Barrack, and John C. Clohisy
Symptoms of pain do not correlate with rotator cuff tear severity, Robert H. Brophy, Matthew V. Smith, Rick W. Wright, and et al
Rapid ertapenem susceptibility testing and Klebsiella pneumoniae carbapenemase phenotype detection in Klebsiella pneumoniae isolates by use of automated microscopy of immobilized live bacterial cells, Carey-Ann D. Burnham, Rachel A. Frobel, Monica L. Herrera, Brian L. Wickes, and D. J. Diekema
De novo meningitis caused by Propionibacterium acnes in a patient with metastatic melanoma, Jason P. Burnham, Benjamin S. Thomas, Sergio E. Trevino, Erin McElvania TeKippe, Carey-Ann D. Burnham, and F. Matthew Kuhlmann
Resting state functional connectivity in early blind humans, Harold Burton, Abraham Z. Snyder, and Marcus E. Raichle
A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level, Deirdre Caffrey, J. Jaime Miranda, Robert H. Gilman, Victor G. Davila-Roman, Lilia Cabrera, Russell Dowling, Talia Stewart, Antonio Bernabe-Ortiz, Robert Wise, Fabiola Leon-Velarde, William Checkley, and CRONICAS Cohort Study Group
Cardiometabolic outcomes in children and adolescents following discontinuation of long-term risperidone treatment, Chadi A. Calarge, Ginger Nicol, Janet A. Schlechte, and Trudy L. Burns
Dorsal and ventral attention systems underlie social and symbolic cueing, Alicia Callejas, Gordon L. Shulman, and Maurizio Corbetta
miR-146a and miR-155 delineate a microRNA fingerprint associated with Toxoplasma persistence in the host brain, Dominique Cannella, Marie-Pierre Brenier-Pinchart, Laurence Braun, Jason M. van Rooyen, Alexandre Bougdour, Olivier Bastien, Michael S. Behnke, Rose-Laurence Curt, Aurelie Curt, Jeroen P.J. Saeij, L. David Sibley, Herve Pelloux, and Mohamed-Ali Hakimi
Pervasive transcription of a herpesvirus genome generates functionally important RNAs, Susan P. Canny, Tiffany A. Reese, L. Steven Johnson, Xin Zhang, Amal Kambal, Erning Duan, Catherine Y. Liu, and Herbert W. Virgin
Resting-state modulation of alpha rhythms by interference with angular gyrus activity, Paolo Capotosto, Claudio Babiloni, Gian Luca Romani, and Maurizio Corbetta
Sex dependent risk factors for mortality after myocardial infarction: Individual patient data meta-analysis, Robert M. Carney, Kenneth E. Freedland, and et al
Using publication metrics to highlight academic productivity and research impact, Christopher R. Carpenter, David C. Cone, and Cathy C. Sarli
Cognitive functioning in young children with type 1 diabetes, M. A. Cato, Nelly Mauras, Jodie Ambrosino, Aiden Bondurant, Amy L. Conrad, Craig Kollman, Peiyao Cheng, Roy W. Beck, Katrina J. Ruedy, Tandy Aye, Allan L. Reiss, Neil H. White, and Tamara Hershey
B-RAF unlocks axon regeneration, Valeria Cavalli and David Holtzman
Smoking cessation is associated with lower rates of mood/anxiety and alcohol use disorders, P. A. Cavazos-Rehg, N. Breslau, D. Hatsukami, M. J. Krauss, E. L. Spitznagel, R. A. Grucza, P. Salyer, S. M. Hartz, and L. J. Bierut
Characterizing the Followers and Tweets of a Marijuana-Focused Twitter Handle, Patricia Cavazos-Rehg, Melissa Krauss, Richard Grucza, and Laura Bierut
Beyond NK cells: the expanding universe of innate lymphoid cells, Marina Cella, Hannah Miller, and Christina Song
Distinguishing West Nile virus infection using a recombinant envelope protein with mutations in the conserved fusion-loop, Stefan Chabierski, Luisa Barzon, Anna Papa, Matthias Niedrig, Jonathan L. Bramson, Justin M. Richner, Giorgio Palu, Michael S. Diamond, and Sebastian Ulbert
Reassessing the impact of smoking on preeclampsia/eclampsia: Are there age and racial differences?, Jen Jen Chang, Jerome F. Strauss III, Jon P. Deshazo, Fidelma B. Rigby, David P. Chelmow, and George A. Macones
Targeting the programmed cell death 1: Programmed cell death ligand 1 pathway reverses T cell exhaustion in patients with sepsis, Katherine Chang, Catherine Svabek, Cristina Vazquez-Guillamet, Bryan Sato, David Rasche, Strother Wilson, Paul Robbins, Nancy Ulbrandt, JoAnn Suzich, Jonathan Green, Andriani C. Patera, Wade Blair, Subramaniam Krishnan, and Richard Hotchkiss
Oral contraceptive use and mortality after 36 years of follow-up in the Nurses' Health Study: Prospective cohort study, Brittany M. Charlton, Janet W. Rich-Edwards, Graham A. Colditz, Stacey A. Missmer, Bernard A. Rosner, Susan E. Hankinson, Frank E. Speizer, and Karin B. Michels
Pathogenic adaptations to host-derived antibacterial copper, Kaveri S. Chaturvedi and Jeffrey P. Henderson
Conservative fluid therapy in septic shock: An example of targeted therapeutic minimization, Catherine Chen and Marin H. Kollef
Copy number analysis of NIPBL in a cohort of 510 patients reveals rare copy number variants and a mosaic deletion, Yu-Wei Cheng, Christopher A. Tan, Agata Minor, Kelly Arndt, Latrice Wysinger, Dorothy K. Grange, Beth A. Kozel, Nathaniel H. Robin, Darrel Waggoner, Carrie Fitzpatrick, Soma Das, and Daniela del Gaudio
Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice, Jianquan Chen, Yu Shi, Jenna Regan, Kannan Karuppaiah, David M. Ornitz, and Fanxin Long
WNT7B promotes bone formation in part through mTORC1, Jianquan Chen, Xiaolin Tu, Emel Esen, Kyu Sang Joeng, Congxin Lin, Jeffrey M. Arbeit, Markus A. Ruegg, Michael N. Hall, Liang Ma, and Fanxin Long
Rab5 isoforms orchestrate a ‘‘Division of Labor’’ in the endocytic network; Rab5C modulates Rac-mediated cell motility, Pin-I Chen, Kristine Schauer, Chen Kong, Andrew R. Harding, Bruno Goud, and Philip D. Stahl
Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes, Shali Chen, Prasanth Puthanveetil, Biao Feng, Scot J. Matkovich, Gerald W. Dorn II, and Subrata Chakrabarti
Patient-controlled epidural Levobupicvacaine with or without Fentanyl for post-cesarean section pain relief, Shin-Yan Chen, Feng-Lin Liu, Yih-Giun Cherng, Shou-Zen Fan, Barbara L. Leighton, Hung-Chi Chang, and Li-Kuei Chen
Mitochondrial genome linearization is a causative factor for cardiomyopathy in mice and Drosophila, Yun Chen, Megan Sparks, Poonam Bhandari, Scot J. Matkovich, and Gerald W. Dorn
A case study of risk factors for lymphatic filariasis in the Republic of Congo, Cédric B. Chesnais, François Missamou, Sébastien D. Pion, Jean Bopda, Frédéric Louya, Andrew C. Majewski, Peter U. Fischer, Gary J. Weil, and Michel Boussinesq
Pharmacologic blockade of JAK1/JAK2 reduces GvHD and preserves the graft-versus-leukemia effect, Jaebok Choi, Matthew L. Cooper, Bader Alahmari, Julie Ritchey, Lynne Collins, Matthew Holt, and John F. DiPersio
Effect of epigallocatechin-3-gallate on graft-versus-host disease, Jaebok Choi, Matthew L. Cooper, Edward D. Ziga, Julie Ritchey, and John F. DiPersio
Cervical spinal cord dimensions and clinical outcomes in adults with Klippel-Feil syndrome: A comparison with matched controls., Woojin Cho, Dong-Ho Lee, Joshua D. Auerbach, Jennifer K. Sehn, Colin E. Nabb, and K D. Riew
Role of NKG2D in obesity-induced adipose tissue inflammation and insulin resistance, Jun-Jae Chung, Mary A. Markiewicz, Bojan Polic, and Andrey S. Shaw
Genetic variation in iron metabolism Is associated with neuropathic pain and pain severity in HIV-infected patients on antiretroviral therapy, David B. Clifford and et al.
Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations, Meghan A. Coghlan, Adrian Shifren, Howard J. Huang, Tonya D. Russell, Robi D. Mitra, Qunyuan Zhang, Daniel J. Wegner, F. Sessions Cole, and Aaron Hamvas
Telavancin for hospital-acquired pneumonia: Clinical response and 28-day survival, G. Ralph Corey, Marin H. Kollef, Andrew F. Shorr, Ethan Rubinstein, Martin E. Stryjewski, Alan Hopkins, and Steven L. Barriere
Gene-wide analysis detects two new susceptibility genes for Alzheimer’s disease, Carlos Cruchaga, Alison M. Goate, and et al
Construction and radiolabeling of adenovirus variants that incorporate human metallothionein into protein IX for analysis of biodistribution, David T. Curiel and et al
Weak grip strength does not predict upper extremity musculoskeletal symptoms or injuries among new workers, Ann Marie Dale, Lesley Addison, Josh Lester, Vicki Kaskutas, and Bradley A. Evanoff
Self-reported physical work exposures and incident carpal tunnel syndrome, Ann Marie Dale, Bethany T. Gardner, Angelique Zeringue, Jaime Strickland, Alexis Descatha, Alfred Franzblau, and Bradley A. Evanoff
The effectiveness of post-offer pre-placement nerve conduction screening for carpal tunnel syndrome, Ann Marie Dale, Bethany T. Gardner, Angelique Zeringue, Robert Werner, Alfred Franzblau, and Bradley A. Evanoff
Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals, Brian P. Daniels, David W. Holman, Lillian Cruz-Orengo, Harsha Jujjavarapu, Douglas M. Durrant, and Robyn S. Klein
Participants’ perceptions of a group based program incorporating hands-on meal preparation and pedometer-based self-monitoring in type 2 diabetes, Kaberi Dasgupta, Soghra Jarvandi, Mirella De Civita, Sabrina Pillay, Samantha Hajna, Rejeanne Gougeon, Abeer Bader, and Deborah Da Costa
Early-onset metabolic syndrome in mice lacking the intestinal uric acid transporter SLC2A9, Brian J. DeBosch, Oliver Kluth, Hideji Fujiwara, Annette Schürmann, and Kelle Moley
Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge, Marina De Filette, Silke Soehle, Sebatian Ulbert, Justin Richner, Michael S. Diamond, Alessandro Sinigaglia, Luisa Barzon, Stefan Roels, Julianna Lisziewicz, Orsolya Lorincz, and Niek N. Sanders
Climbing the vertebrate branch of U1A/U2B″ protein evolution, Kimberly J. Delaney, Sandra G. Williams, Mariah N. Lawler, and Kathleen B. Hall
Prevalence, correlates, and prognosis of peripheral artery disease in rural ecuador-rationale, protocol, and phase I results of a population-based survey: an atahualpa project-ancillary study, Oscar H. Del Brutto, Mark J. Sedler, Robertino M. Mera, Pablo R. Castillo, Elizabeth H. Cusick, Jadry A. Gruen, Kelsie J. Phelan, Victor J. Del Brutto, Mauricio Zambrano, and David L. Brown
Mindfulness may both moderate and mediate the effect of physical fitness on cardiovascular responses to stress: A speculative hypothesis, Marcelo M.P. Demarzo, Jesus Montero-Marin, Phyllis K. Stein, Ausias Cebolla, Jaime G. Provinciale, and Javier Garcia-Campayo
A chimeric virus-mouse model system for evaluating the function and inhibition of papain-like proteases of emerging coronaviruses, Xufang Deng, Sudhakar Agnihothram, Anna M. Mielech, Daniel B. Nichols, Michael W. Wilson, Sarah E. St. John, Scott D. Larsen, Andrew D. Mesecar, Deborah J. Lenschow, Ralph S. Baric, and Susan C. Baker
Do symptoms and physical examination findings predict elbow pain and functional outcomes in a working population?, Alexis Descatha, Ann Marie Dale, Lisa Jaegers, and Bradley Evanoff
An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: Functional, metabolic, and differential network analysis, Sriram Devanathan, Timothy Whitehead, George G. Schweitzer, Nicole Fettig, Attila Kovacs, Kenneth S. Korach, Brian N. Finck, and Kooresh I. Shoghi
Kidney transplantation in children, Vikas R. Dharnidharka, Paolo Fiorina, and William E. Harmon
Vaccine-induced protection of rhesus macaques against plasma viremia after intradermal infection with a European lineage 1 strain of West Nile virus, Michael S. Diamond and et al
Clonal architectures and driver mutations in metastatic melanomas, Li Ding, Minjung Kim, Krishna L. Kanchi, Nathan D. Dees, Charles Lu, Malachi Griffith, David Fenstermacher, Hyeran Sung, Christopher A. Miller, Brian Goetz, Michael C. Wendl, Obi Griffith, Lynn A. Cornelius, Gerald P. Linette, Joshua F. McMichael, Vernon K. Sondak, Ryan C. Fields, Timothy J. Ley, James J. Mule, Richard K. Wilson, and Jeffrey S. Weber
The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes, Li Ding, Richard K. Wilson, Elaine R. Mardis, and et al
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia., L. Ding, C. Lu, R. S. Fulton, E. Mardis, R. K. Wilson, and et al
Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies, John F. DiPersio and et al
Monitoring of biodistribution and persistence of conditionally replicative adenovirus in a murine model of ovarian cancer using capsid-incorporated mCherry and expression of human somatostatin receptor subtype 2 gene, Igor P. Dmitriev, Elena A. Kashentseva, Walter J. Akers, Samuel Achilefu, David T. Curiel, and et al
DLS 5.0 - The biomechanical effects of dynamic locking screws, Stefan Dobele, Michael Gardner, Steffen Schroter, Dankward Hontzsch, Ulrich Stockle, and Thomas Freude
Diurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system, Justyna A. Dobrowolska, Tom Kasten, Yafei Huang, Tammie L. S. Benzinger, Wendy Sigurdson, Vitaliy Ovod, John C. Morris, and Randall J. Bateman
"Everyone should be able to choose how they get around": How Topeka, Kansas, passed a complete streets resolution, Elizabeth A. Dodson, Marvin Langston, Lauren C. Cardick, Nancy Johnson, Paula Clayton, and Ross C. Brownson
Probiotic-associated aspiration pneumonia due to Lactobacillus rhamnosus, Christopher D. Doern, Sean T. Nguyen, Folashade Afolabi, and Carey-Ann D. Burnham
Cross talk between the Cell Wall Integrity and Cyclic AMP/Protein Kinase A pathways in Cryptococcus neoformans, Maureen J. Donlin, Rajendra Upadhya, Kimberly J. Gerik, Woei Lam, Laura G. VanArendonk, Charles A. Specht, Neil K. Sharma, and Jennifer K. Lodge
Impact of genetic background on neonatal lethality of Gga2 gene-trap mice, Balraj Doray, Jennifer Govero, and Stuart Kornfeld
Development and feasibility of a home-based education model for families of children with sickle cell disease, Catherine Hoyt Drazen, Regina Abel, Terianne Lindsey, and Allison A. King
Curricular priorities for business ethics in medical practice and research: Recommendations from Delphi consensus panels, James M. DuBois, Elena M. Kraus, Kamal Gursahani, Anthony Mikulec, and Erin Bakanas
Genetic and environmental risk for major depression in African-American and European-American women, Alexis E. Duncan, Melissa A. Munn-Chernoff, Darrell L. Hudson, Michaela A. Eschenbacher, Arpana Agrawal, Julia D. Grant, Elliot C. Nelson, Mary Waldron, Anne L. Glowinski, Carolyn E. Sartor, Kathleen K. Bucholz, Pamela A.F. Madden, and Andrew C. Heath
Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii, Christopher D. Dupont, David A. Christian, Elizabeth M. Selleck, Marion Pepper, Michael Leney-Greene, Gretchen Harms Pritchard, Anita A. Koshy, Sagie Wagage, Morgan A. Reuter, L. David Sibley, Michael R. Betts, and Christopher A. Hunter
Potent Dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement, Melissa A. Edeling, S. Kyle Austin, Bimmi Shrestha, Kimberly A. Dowd, Swati Mukherjee, Christopher A. Nelson, Syd Johnson, Manu N. Mabila, Elizabeth A. Christian, Joseph Rucker, Theodore C. Pierson, Michael S. Diamond, and Daved H. Fremont
Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states, Nadine Ehmann, Sebastian van de Linde, Amit Alon, Dmitrij Ljaschenko, Xi Zhen Keung, Thorge Holm, Annika Rings, Aaron DiAntonio, Stefan Hallermann, Uri Ashery, Manfred Heckmann, Markus Sauer, and Robert J. Kittel
Suicide genes: Monitoring cells in patients with a safety switch, Linda G. Eissenberg, Michael Rettig, Farrokh Dehdashti, David Piwnica-Worms, and John F. DiPersio
A broadly implementable research course in phage discovery and genomics for first-year undergraduate students, Sarah C.R. Elgin, Christopher D. Shaffer, and et al
Wise regulates bone deposition through genetic interactions with Lrp5, Debra L. Ellies, Androulla Economou, Beth Viviano, Jean-Philippe Rey, Stephanie Paine-Saunders, Robb Krumlauf, and Scott Saunders
Health care system collaboration to address chronic diseases: A nationwide snapshot from state public health practitioners, Lindsay Elliott, Timothy D. McBride, Peg Allen, Rebekah R. Jacob, Ellen Jones, Jon Kerner, and Ross C. Brownson
Predicting response and survival in chemotherapy-treated triple-negative breast cancer, Matthew J. Ellis, E. Mardis, Tammi L. Vickery, and et al
A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis, Patrik Engstrom, K. Syam Krishnan, Bidong D. Ngyuen, Erik Chorell, Johan Normark, Jim Silver, Robert J. Bastidas, Matthew D. Welch, Scott J. Hultgren, Hans Wolf-Watz, Raphael H. Valdivia, Fredrik Almqvist, and Sven Bergstrom
Cost-effectiveness of family-based group treatment for child and parental obesity, Leonard H. Epstein, Rocco A. Paluch, Brian H. Wrotniak, Tinuke Oluyomi Daniel, Denise Wilfley, and Eric Finkelstein
Essentials and guidelines for clinical medical physics residency training programs: executive summary of AAPM Report Number 249, Jacqueline Esthappan and et al
A conceptual model of musculoskeletal disorders for occupational health practitioners, Bradley A. Evanoff, Ann Marie Dale, and Alexis Descatha
Using job-title-based physical exposures from O*NET in an epidemiological study of carpal tunnel syndrome, Bradley A. Evanoff, Angelique Zeringue, Alfred Franzblau, and Ann Marie Dale
Human coronary plaque wall thickness correlated positively with flow shear stress and negatively with plaque wall stress: An IVUS-based fluid-structure interaction multi-patient study, Rui Fan, Dalin Tang, Chun Yang, Jie Zheng, Richard Bach, Liang Wang, David Muccigrosso, Kristen Billiar, Jian Zhu, Genshan Ma, Akiko Maehara, and Gary S. Mintz
Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol, Mary F. Feitosa, Mary K. Wojczynski, Robert Straka, Candace M. Kammerer, Joseph H. Lee, Aldi T. Kraja, Kaare Christensen, Anne B. Newman, Michael A. Province, and Ingrid B. Borecki
Autophagy and phagocytosis converge for better vision, Thomas A. Ferguson and Douglas R. Green
A retrospective analysis of survival and prognostic factors after stereotactic radiosurgery for aggressive meningiomas, Daniel J. Ferraro, Ryan K. Funk, John William Blackett, Michelle R. Ju, Todd A. DeWees, Michael R. Chicoine, Joshua L. Dowling, Keith M. Rich, Robert E. Drzymala, Imran Zoberi, Joseph R. Simpson, and Jerry J. Jaboin
High pressure freezing/freeze substitution fixation improves the ultrastructural assessment of Wolbachia endosymbiont – filarial nematode host interaction, Kerstin Fischer, Wandy L. Beatty, Gary J. Weil, and Peter U. Fischer
Designing vaccines to neutralize effective toxin delivery by enterotoxigenic Escherichia coli, James M. Fleckenstein and Alaullah Sheikh
Optimal body weight for health and longevity: Bridging basic, clinical, and population research, Luigi Fontana and Frank B. Hu
ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis, Jason T. Forys, Catherine E. Kuzmicki, Anthony J. Saporita, Crystal L. Winkeler, Leonard B. Maggi Jr., and Jason D. Weber
