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Submissions from 2007

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Zoonotic orthopoxviruses encode a high-affinity antagonist of NKG2D, Jessica A. Campbell, David S. Trossman, Wayne M. Yokoyama, and Leonidas N. Carayannopoulos

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Comparisons of mutants lacking the golgi UDP-galactose or GDP-mannose transporters establish that phosphoglycans are important for promastigote but not amastigote virulence in Leishmania major, Althea A. Capul, Suzanne Hickerson, Tamara Barron, Salvatore J. Turco, and Stephen M. Beverley

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Brain fatty acid synthase activates PPARa to maintain energy homeostasis, Manu V. Chakravarthy, Yimin Zhu, Miguel Lopez, Li Yin, David F. Wozniak, Trey Coleman, Zhiyuan Hu, Michael Wolfgang, Antonio Vidal-Puig, M. Daniel Lane, and Clay F. Semenkovich

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Genetic Analysis Workshop 15: Gene expression analysis and approaches to detecting multiple functional loci, Heather J. Cordell, Mariza de Andrade, Marie-Claude Babron, Christopher W. Bartlett, Joseph Beyene, Heike Bickeböller, Robert Culverhouse, L Adrienne Cupples, E Warwick Daw, Josee Dupuis, Catherine T. Falk, Saurabh Ghosh, Katrina A. Goddard, Ellen L. Goode, Elizabeth R. Hauser, Lisa J. Martin, Maria Martinez, Kari E. North, Nancy L. Saccone, Silke Schmidt, William Tapper, Duncan Thomas, David Tritchler, Veronica J. Vieland, Ellen M. Wijsman, Marsha A. Wilcox, John S. Witte, Qiong Yang, Andreas Ziegler, Laura Almasy, and Jean W. MacCluer

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The pathogenic fungus Cryptococcus neoformans expresses two functional GDP-mannose transporters with distinct expression patterns and roles in capsule synthesis, Tricia R. Cottrell, Cara L. Griffith, Hong Liu, Ashley A. Nenninger, and Tamara L. Doering

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Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms, Stephane Daffis, Melanie A. Samuel, Brian C. Keller, Michael Gale Jr., and Michael S. Diamond

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Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival, Antara Datta, Lee Silverman, Andrew J. Phipps, Hajime Hiraragi, Lee Ratner, and Michael D. Lairmore

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Computational identification and functional validation of regulatory motifs in cartilage-expressed genes, Sherri R. Davies, Li-Wei Chang, Debabrata Patra, Xiaoyun Xing, Karen Posey, Jacqueline Hecht, Gary D. Stormo, and Linda J. Sandell

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The feasibility of oligogenic combined segregation and linkage analysis in CEPH pedigrees, E Warwick Daw and Robert Yu

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Frequent gain and loss of functional transcription factor binding sites, Scott W. Doniger and Justin C. Fay

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The γ/σ1 and α/σ2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site, Balraj Doray, Intaek Lee, Jane Knisely, Guojun Bu, and Stuart Kornfeld

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Severity of Clostridium difficile-associated disease (CDAD) in allogeneic stem cell transplant recipients: Evaluation of a CDAD severity grading system, Erik R. Dubberke, Justin Sadhu, Robert Gatti, Kimberly A. Reske, John F. DiPersio, Steven M. Devine, and Victoria J. Fraser

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Clustering of eating disorder symptoms in a general population female twin sample: A latent class analysis, Alexis E. Duncan, Kathleen K. Bucholz, Rosalind J. Neuman, Arpana Agrawal, Pamela A F Madden, and Andrew C. Heath

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Divergent evolution of arrested development in the dauer stage of Caenorhabditis elegans and the infective stage of Heterodera glycines, Axel A. Elling, Makedonka Mitreva, Justin Recknor, Xiaowu Gai, John Martin, Thomas R. Maier, Jeffrey P. McDermott, Tarek Hewezi, David McK Bird, Eric L. Davis, Richard S. Hussey, Dan Nettleton, James P. McCarter, and Thomas J. Baum

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The effect of compliance on the impact of mass drug administration for elimination of lymphatic filariasis in Egypt, Maged El Setouhy, Khaled M. Abd Elaziz, Hanan Helmy, Hoda A. Farid, Hussein A. Kamal, Reda M.R. Ramzy, William D. Shannon, and Gary J. Weil

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Control of inward rectifier K channel activity by lipid tethering of cytoplasmic domains, Decha Enkvetchakul, Iana Jeliazkova, Jaya Bhattacharyya, and Colin G. Nichols

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A critical appraisal of molecular xenomonitoring as a tool for assessing progress toward elimination of lymphatic filariasis, Hoda A. Farid, Zakariya S. Morsy, Hanan Helmy, Reda M.R. Ramzy, Maged El Setouhy, and Gary J. Weil

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Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial, Thomas Ferkol and et al

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Persistence of Brugia malayi DNA in vector and non-vector mosquitoes: Implications for xenomonitoring and transmission monitoring of lymphatic filariasis, Peter Fischer, Sara M. Erickson, Kerstin Fischer, Jeremy F. Fuchs, Ramakrishna U. Rao, Bruce M. Christensen, and Gary J. Weil

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Ventilator-associated pneumonia in neonatal and pediatric intensive care unit patients, Elizabeth Foglia, Mary Dawn Meier, and Alexis Elward

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Impaired mononuclear cell immune function in extreme obesity is corrected by weight loss, Luigi Fontana, J. Christopher Eagon, Marco Colonna, and Samuel Klein

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Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk, Luigi Fontana, Timothy E. Meyer, Samuel Klein, and John O. Holloszy

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Common genetic risk of major depression and nicotine dependence: The contribution of antisocial traits in a United States veteran male twin cohort, Qiang Fu, Andrew C. Heath, Kathleen K. Bucholz, Michael J. Lyons, Ming T. Tsuang, William R. true, and Seth A. Eisen

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Toxoplasma gondii strains defective in oral transmission are also defective in developmental stage differentiation, Blima Fux, Julie Nawas, Asis Khan, Darcy B. Gill, Chunlei Su, and L David Sibley

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Escherichia coli from urine of female patients with urinary tract infections is competent for intracellular bacterial community formation, Corinne K. Garofalo, Thomas M. Hooton, Steven M. Martin, Walter E. Stamm, Joseph J. Palermo, Jeffrey I. Gordon, and Scott J. Hultgren

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Identification of a novel polyomavirus from patients with acute respiratory tract infections, Anne M. Gaynor, Michael D. Nissen, David M. Whiley, Ian M. Mackay, Stephen B. Lambert, Guang Wu, Daniel C. Brennan, Gregory A. Storch, Theo P. Sloots, and David Wang

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NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat, Antonino Germanò, Mariella Caffo, Filippo Flavio Angileri, Francesca Arcadi, Jennifer Newcomb, Gerardo Caruso, Francesco Meli, Jose A. Pineda, Stephen B. Lewis, Kevin K. W. Wang, Placido Bramanti, Chiara Costa, and Ronald L. Hayes

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Use of recombinant factor VIIa for hip surgery in a patient with factor-VII deficiency: A case report, Priya K. Gopalan, John C. Clohisy, Amanda F. Cashen, and Charles S. Eby

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Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCγ2 signaling axis in mice, Daniel B. Graham, Charles M. Robertson, Jhoanne Bautista, Francesca Mascarenhas, M. Julia Diacovo, Vivianne Montgrain, Siu Kit Lam, Viviana Cremasco, W. Michael Dunne, Roberta Faccio, Craig M. Coopersmith, and Wojciech Swat

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An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells, Daniel B. Graham, Linda M. Stephenson, Siu Kit Lam, Karry Brim, Hyang Mi Lee, Jhoanne Bautista, Susan Gilfillan, Shreeram Akilesh, Keiko Fujikawa, and Wojciech Swat

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A high-resolution map of segmental DNA copy number variation in the mouse genome, Timothy A. Graubert, Patrick Cahan, Deepa Edwin, Rebecca R. Selzer, Todd A. Richmond, Peggy S. Eis, William D. Shannon, Xia Li, Howard L. McLeod, James M. Cheverud, and Timothy J. Ley

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Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome, Tina Graves, Robert Fulton, Elaine R. Mardis, Richard K. Wilson, and et al

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Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia, Mitchell H. Grayson, Dorothy Cheung, Michelle M. Rohlfing, Robert Kitchens, Daniel E. Spiegel, Jennifer Tucker, John T. Battaile, Yael Alevy, Le Yan, Eugene Agapov, Edy Y. Kim, and Michael J. Holtzman

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E2F8 is a nonreceptor activator of heterotrimeric G proteins, Ian S. Hagemann, Kirk D. Narzinski, and Thomas J. Baranski

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Organogenesis of kidney and endocrine pancreas: The window opens, Marc R. Hammerman

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Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D, Kevan L. Hartshorn, Mitchell R. White, Tesfaldet Tecle, Ida Tornoe, Grith L. Sorensen, Erika C. Crouch, and Uffe Holmskov

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Haplotyping a quantitative trait with a high-density map in experimental crosses, Wei Hou, John Stephen F. Yap, Song Wu, Tian Liu, James M. Cheverud, and Rongling Wu

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Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes, Ching-Yu Huang, Girdhar G. Sharma, Laura M. Walker, Craig H. Bassing, Tej K. Pandita, and Barry P. Sleckman

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Changing human visual field organization from early visual to extra-occipital cortex, Anthony I. Jack, Gaurav H. Patel, Serguei V. Astafiev, Abraham Z. Snyder, Erbil Akbudak, Gordon L. Shulman, and Maurizio Corbetta

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Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: Applications in diagnostic imaging and therapy, Hiroyuki Kashiwagi, Jonathan E. McDunn, Peter O. Simon Jr, Peter S. Goedegebuure, Jinbin Xu, Lynne Jones, Katherine Chang, Fabian Johnston, Kathryn Trinkaus, Richard S. Hotchkiss, Robert H. Mach, and William G. Hawkins

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Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice, Jennifer Kelly, Aslam Ali Khan, Jiyi Yin, Thomas A. Ferguson, and Rajendra S. Apte

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Pancreatitis following Olanzapine Therapy: A Report of Three Cases, Thomas A. Kerr, Sreenivasa Jonnalagadda, Chandra Prakash, and Riad Azar

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Rheumatoid arthritis, item response theory, Blom transformation, and mixed models, Aldi T. Kraja, Jon Corbett, An Ping, Rosa S. Lin, Petra A. Jacobsen, Michael Crosswhite, Ingrid B. Borecki, and Michael A. Province

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Circumstances of patient falls and injuries in 9 hospitals in a midwestern healthcare system, Melissa J. Krauss, Sheila L. Nguyen, Wm. Claiborne Dunagan, Stanley Birge, Eileen Costantinou, Shirley Johnson, Barbara Caleca, and Victoria J. Fraser

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Polyamine permeation and rectification of kir4.1 channels, Yuri V. Kucheryavykh, Wade L. Pearson, Harley T. Kurata, Misty J. Eaton, Serguei N. Skatchkov, and Colin G. Nichols

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The role of the cytoplasmic pore in inward rectification of Kir2.1 channels, Harley T. Kurata, Wayland W. Cheng, Christine Arrabit, Paul A. Slesinger, and Colin G. Nichols

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Continued use of an integrated meter with electronic logbook maintains improvements in glycemic control beyond a randomized, controlled trial, Lori M. B. Laffel, William C. Hsu, Janet B. McGill, Luigi Meneghini, and Lisa K. Volkening

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The bandit, a new DNA transposon from a hookworm— possible horizontal genetic transfer between host and parasite, Thewarach Laha, Alex Loukas, Supatra Wattanasatitarpa, Jenjira Somprakhon, Nonglack Kewgrai, Paiboon Sithithaworn, Sasithorn Kaewkes, Makedonka Mitreva, and Paul J. Brindley

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Clostridium difficile in the intensive care unit: Epidemiology, costs, and colonization pressure, Steven J. Lawrence, Laura A. Puzniak, Brooke N. Shadel, Kathleen N. Gillespie, Marin H. Kollef, and Linda M. Mundy

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A little stress is good: IFN-γ, demyelination, and multiple sclerosis, Jason R. Lees and Anne H. Cross

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Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli, Yvonne M. Lee, Karen W. Dodson, and Scott J. Hultgren

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Management of juvenile idiopathic scoliosis, Lawrence G. Lenke and Matthew B. Dobbs

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Calmodulin kinase II inhibition enhances ischemic preconditioning by augmenting ATP-sensitive K+ current, Jingdong Li, Celine Marionneau, Olha Koval, Leonid Zingman, Peter J. Mohler, Jeanne M. Nerbonne, and Mark E. Anderson

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PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancer, W. T. Lim, W. H. Zhang, C. R. Miller, J. W. Watters, F. Gao, A. Viswanathan, R Govindan, and H. L. McLeod

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Vascular injury from an arterial closure device, Jeffrey P. C. Lin, Brian G. Rubin, and William D. Middleton

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Functional association of Sun1 with nuclear pore complexes, Qian Liu, Nelly Pante, Tom Misteli, Mohamed Elsagga, Melissa Crisp, Didier Hodzic, Brian Burke, and Kyle J. Roux

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Contribution of invariant residues to the function of Rgg family transcription regulators, Jennifer Loughman and Michael G. Caparon

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Diffusion tensor imaging predicts hyperacute spinal cord injury severity, David N. Loy, Joong Hee Kim, Mingqiang Xie, Robert E. Schmidt, Kathryn Trinkaus, and Sheng-Kwei Song

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Psychotropic prescriptions in a sample including both healthy and mood and disruptive disordered preschoolers: relationships to diagnosis, impairment, prescriber type, and assessment methods, Joan L. Luby, Melissa Meade Stalets, and Andy C. Belden

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Three clinical cases of DSM-IV mania symptoms in preschoolers, Joan Luby, Mini Tandon, and Ginger Nicol

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Psychometric properties of DSM assessments of illicit drug abuse and dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), M. T. Lynskey and A. Agrawal

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Clamping the Mec1/ATR checkpoint kinase into action, Jerzy Majka and Peter M.J. Burgers

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Case-control study of surgical site infections associated with pacemakers and implantable cardioverter-defibrillators, Jonas Marschall, Diane Hopkins-Broyles, Marilyn Jones, Victoria J. Fraser, and David K. Warren

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Catheter-associated bloodstream infections in general medical patients outside the intensive care unit: A surveillance study, Jonas Marschall, Carole Leone, Marilyn Jones, Deborah Nihill, Victoria J. Fraser, and David K. Warren

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Regulation of KATP channel expression and activity by the SUR1 Nucleotide Binding Fold 1, Ricard Masia, George Caputa, and Colin G. Nichols

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Nectin-like proteins mediate axon-Schwann cell interactions along the internode and are essential for myelination, Patrice Maurel, Steven Einheber, Jolanta Galinska, Pratik Thaker, Isabel Lam, Marina B. Rubin, Steven S. Scherer, Yoshinuri Murakami, David H. Gutmann, and James L. Salzer

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Preparation of antidepressants for use in preclinical research, Jonathan E. McConathy, Catherine Capello, Nachwa Jarkas, Zachary N. Stowe, and Michael J. Owens

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Whole-mount techniques to evaluate subepithelial cellular populations in the adult mouse intestine, Keely G. McDonald and Rodney D. Newberry

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Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4, Michael D. McLellan, Yumi Kasai, Tracie L. Milner, Ginger A. Fewell, Lucinda L. Fulton, Elaine R. Mardis, Richard K. Wilson, and et al.

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PI3K(p110α) inhibitors as anti-cancer agents: Minding the heart, Julie R. McMullen and Patrick Y. Jay

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Health care-associated pneumonia and community-acquired pneumonia: A single-center experience, Scott T. Micek, Katherine E. Kollef, Richard M. Reichley, Nareg Roubinian, and Marin H. Kollef

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Addition of vasopressin to norepinephrine as independent predictor of mortality in patients with refractory septic shock: An observational study, Scott T. Micek, Poorvi Shah, James M. Hollands, Rina A. Shah, William D. Shannon, and Marin H. Kollef

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Exploring the inter-relationship of smoking age-at-onset, cigarette consumption and smoking persistence: Genes or environment?, Katherine I. Morley, Michael T. Lynskey, Pamela A F Madden, Susan A. Treloar, Andrew C. Heath, and Nicholas G. Martin

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Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model, John D. Morrey, Venkatraman Siddharthan, Aaron L. Olsen, Hong Wang, Justin G. Julander, Jeffery O. Hall, Hua Li, Jeffrey L. Nordstrom, Scott Koenig, Syd Johnson, and Michael S. Diamond

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Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease, Odity Mukherjee, John SK Kauwe, Kevin Mayo, John C. Morris, and Alison M. Goate

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Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii, Kisaburo Nagamune, Wandy L. Beatty, and L. David Sibley

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Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis, Kisaburo Nagamune, Silvia N.J. Moreno, and L. David Sibley

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MultiCode-PLx system for multiplexed detection of seventeen respiratory viruses, Frederick S. Nolte, David J. Marshall, Christopher Rasberry, Sabina Schievelbein, Grier G. Banks, Gregory A. Storch, Max Q. Arens, Richard S. Buller, and James R. Prudent

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Rapid maturation of effector T cells in tumors, but not lymphoid organs, during tumor regression, Lyse A. Norian and Paul M. Allen

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Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment, Carol S. North, Barry A. Hong, and David H. Alpers

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Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks, Olanrewaju Okusanya, Alan Forrest, Robin DiFrancesco, Sanela Bilic, Susan Rosenkranz, Michael F. Para, Elizabeth Adams, Kevin E. Yarasheski, Richard C. Reichman, Gene D. Morse, and ACTG 5043 Protocol Team

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Site-1 protease is essential for endochondral bone formation in mice, Debabrata Patra, Xiaoyun Xing, Sherri Davies, Jennifer Bryan, Carl Franz, Ernst B. Hunziker, and Linda J. Sandell

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Toward an understanding of risk factors for anorexia nervosa: A case-control study, K. M. Pike, A. Hilbert, D. E. Wilfley, C. G. Fairburn, F. A. Dohm, B. T. Walsh, and R. Striegel-Moore

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Clinical significance of αII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury, Jose A. Pineda, Stephen B. Lewis, Alex B. Valadka, Linda Papa, H. Julia Hannay, Shelley C. Heaton, Jason A. Demery, Ming Cheng Liu, Jada M. Aikman, Veronica Akle, Gretchen M. Brophy, Joseph J. Tepas III, Kevin K. W. Wang, Claudia S. Robertson, and Ronald L. Hayes

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Intracellular mediators of transforming growth factor β superfamily signaling localize to endosomes in chicken embryo and mouse lenses in vivo, Ramya Rajagopal, Shunsuke Ishii, and David C. Beebe

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Polony analysis of gene expression in ES cells and blastocysts, C. Rieger, R. Poppino, R. Sheridan, K. Moley, R. Mitra, and D. Gottlieb

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Molecular refinement of gibbon genome rearrangements, Roberta Roberto, Oronzo Capozzi, Richard K. Wilson, Elaine R. Mardis, Mariana Lomiento, Eray Tuzun, Ze Cheng, Alan R. Mootnick, Nicoletta Archidiacono, Mariano Rocchi, and Evan E. Eichler

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Anionic lipids enriched at the ExPortal of Streptococcus pyogenes, Jason W. Rosch, Fong Fu Hsu, and Michael G. Caparon

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Detection of intracellular bacterial communities in human urinary tract infection, David A. Rosen, Thomas M. Hooton, Walter E. Stamm, Peter A. Humphrey, and Scott J. Hultgren

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Antiretroviral drug levels and interactions affect lipid, lipoprotein, and glucose metabolism in HIV-1 seronegative subjects: A pharmacokinetic- pharmacodynamic analysis, Susan Rosenkranz, Kevin E. Yarasheski, Michael F. Para, Richard C. Reichman, and Gene D. Morse

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Identification and characterization of small molecules that inhibit intracellular toxin transport, Jose B. Saenz, Teresa A. Doggett, and David B. Haslam

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Conduct disorder among Asians and Native Hawaiian/Pacific Islanders in the USA, J. T. Sakai, N. K. Risk, C. A. Tanaka, and R. K. Price

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Fine mapping of mouse QTLs for fatness using SNP data, Armin O. Schmitt, Hadi Al-Hasani, James M. Cheverud, Daniel Pomp, Lutz Bünger, and Gudrun A. Brockmann

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Increasing incidence of sterile-site infections due to non-multidrug- resistant, oxacillin-resistant Staphylococcus aureus among hospitalized patients, Garrett E. Schramm, Jennifer A. Johnson, Joshua A. Doherty, Scott T. Micek, and Marin H. Kollef

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Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: A before-after trial, Douglas J E Schuerer, Ingrid B. Borecki, David K. Warren, Victoria J. Fraser, John E. Mazuski, Walter A. Boyle, Timothy G. Buchman, Craig M. Coppersmith, and et al

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X-linked idiopathic infantile nystagmus associated with a missense mutation in FRMD7, Alan Shiels, Thomas M. Bennett, Jessica B. Prince, and Lawrence Tychsen

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Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice, Jiusong Sun, Galina K. Sukhova, Min Yang, Paul J. Wolters, Lindsey A. MacFarlane, Peter Libby, Chingxiu Sun, Yadong Zhang, Jian Liu, Terri L. Ennis, Rebecca Knispel, Wanfen Xiong, Robert W. Thompson, B. Timothy Baxter, and Guo-Ping Shi

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The neuroendocrine impact of chronic stress on cancer, Premal H. Thaker, Susan K. Lutgendorf, and Anil K. Sood

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Causing and curing infantile esotropia in primates: The role of decorrelated binocular input (an American Ophthalmological Society thesis), Lawrence Tychsen

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Differences in rust in hearing aid batteries across four manufacturers, four battery sizes, and five durations of exposure, Michael Valente, Jamie H. Cadieux, Laura Flowers, John G. Newman, Juergen Scherer, and Gerg Gephart