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Submissions from 2017

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Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer, Maria Laura Pati, John R. Hornick, Mauro Niso, Francesco Berardi, Dirk Spitzer, Carmen Abate, and William Hawkins

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Enabling open science for health research: Collaborative Informatics Environment for Learning on Health Outcomes (CIELO), Philip Payne, Omkar Lele, Beth Johnson, and Erin Holve

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Quality-adjusted survival with combination nal-IRI þ 5-FU/LV vs 5-FU/LV alone in metastatic pancreatic cancer patients previously treated with gemcitabine-based therapy: A Q-TWiST analysis, Uwe Pelzer, Jean-Frédéric Blanc, Davide Melisi, Antonio Cubillo, Daniel D. Von Hoff, Andrea Wang-Gillam, Li-Tzong Chen, Jens T. Siveke, Yin Wan, Caitlyn T. Solem, Marc F. Botteman, Yoojung Yang, Floris A. de Jong, and Richard A. Hubner

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Familial screening for left-sided congenital heart disease: What is the evidence? What is the cost?, Daniel J. Perry, Connor R. Mullen, Horacio G. Carvajal, Anoop K. Brar, and Pirooz Eghtesady

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Tumor diversity and evolution revealed through RADseq, Elizabeth B. Perry, Alvin Makohon-Moore, Caihong Zheng, Charles K. Kaufman, Jun Cai, Christine A. Iacobuzio-Donahue, and Richard M. White

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Murine models of gastric corpus preneoplasia, Christine P. Petersen, Jason C. Mills, and James R. Goldenring

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Clinical outcomes of remote ischemic preconditioning prior to cardiac surgery: A meta‐analysis of randomized controlled trials, Brian Pierce, Indra Bole, Vaiibhav Patel, and David L. Brown

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Bacterial infections in neonates following mupirocin-based MRSA decolonization: A multicenter cohort study, Rebecca Pierce, Kristina Bryant, Alexis Elward, Justin Lessler, and Aaron M. Milstone

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Enrichment and molecular analysis of breast cancer disseminated tumor cells from bone marrow using microfiltration, Sreeraj G. Pillai, Peixuan Zhu, Chidananda M. Siddappa, Daniel L. Adams, Shuhong Li, Olga V. Makarova, Pete Amstutz, Ryan Nunley, Cha-Mei Tang, Mark A. Watson, and Rebecca L. Aft

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Standards for Reporting Implementation Studies (StaRI): Explanation and elaboration document, Hilary Pinnock, Melanie Barwick, Christopher R. Carpenter, Sandra Eldridge, Gonzalo Grandes, Chris J. Griffiths, Jo Rycroft-Malone, Paul Meissner, Elizabeth Murray, Anita Patel, Aziz Sheikh, and Stephanie J.C. Taylor

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Standards for Reporting Implementation Studies (StaRI) statement, Hilary Pinnock, Melanie Barwick, Christopher R. Carpenter, Sandra Eldridge, Gonzalo Grandes, Chris J. Griffiths, Jo Rycroft-Malone, Paul Meissner, Elizabeth Murray, Anita Patel, Aziz Sheikh, and Stephanie J.C. Taylor

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Early childhood lung function is a stronger predictor of adolescent lung function in cystic fibrosis than early Pseudomonas aeruginosa infection, Jessica E. Pittman, Hannah Noah, Hollin E. Calloway, Stephanie D. Davis, Margaret W. Leigh, Mitchell Drumm, Scott D. Sagel, Frank J. Accurso, Michael R. Knowles, and Marci K. Sontag

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SpxA1 and SpxA2 act coordinately to fine-tune stress responses and virulence in Streptococcus pyogenes, Gary C. Port, Zachary T. Cusumano, Paul R. Tumminello, and Michael G. Caparon

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Computed tomography and magnetic resonance findings of fat-poor angiomyolipomas, Aaron M. Potretzke, Theodora A. Potretzke, Tyler M. Bauman, B. Alexander Knight, Alyssa M. Park, Jonathan M. Mobley, Robert Sherburne Figenshau, and Cary Lynn Siegel

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Draft genome sequence of the blaOXA-436- and blaNDM-1-harboring Shewanella putrefaciens SA70 isolate, Robert F. Potter, Alaric W. D-Souza, Meghan A. Wallace, Angela Shupe, Sanket Patel, Danish Gul, Jennie H. Kwon, Saadia Andleeb, Carey-Ann D. Burnham, and Gautam Dantas

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Thirty-day readmissions in hospitalized patients who received bezlotoxumab with antibacterial drug treatment for Clostridium difficile infection, Vimalanand S. Prabhu, Oliver A. Cornely, Yoav Golan, Erik R. Dubberke, Sebastian M. Heimann, Mary E. Hansen, Jane Liao, Alison Pedley, Mary Beth Dorr, and Stephen Marcella

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Reliability of analysis of the bone mineral density of the second and fifth metatarsals using dual-energy x-ray absorptiometry (DXA), N. Stewart Pritchard, James M. Smoliga, Anh-Dung Nguyen, Micah C. Branscomb, David R. Sinacore, Jeffrey B. Taylor, and Kevin R. Ford

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Neural circuitry at age 6 months associated with later repetitive behavior and sensory responsiveness in autism, John R. Pruett Jr., Kelly N. Botteron, and et al

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The emergence of network inefficiencies in infants with autism spectrum disorder, John R. Pruett Jr., Kelly N. Botteron, Robert C. McKinstry, and et al

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An audience research study to disseminate evidence about comprehensive state mental health parity legislation to US State policymakers: Protocol, Jonathan Purtle, Félice Lê-Scherban, Paul Shattuck, Enola K. Proctor, and Ross C. Brownson

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Endotracheal tube-induced sore throat pain and inflammation is coupled to the release of mitochondrial DNA, Carlos A. Puyo, Daniela Peruzzi, Alexander Earhart, Evan Roller, Menelaos Karanikolas, Marin H. Kollef, Alexander S. Krupnick, Daniel Kreisel, Mohsen Ibrahim, and Andrew E. Gelman

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An optimized, broadly applicable piggyBac transposon induction system, Zongtai Qi, Michael Nathaniel Wilkinson, Xuhua Chen, Sumithra Sankararaman, David Mayhew, and Robi David Mitra

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Effects of two years of calorie restriction on aerobic capacity and muscle strength, Susan B. Racette, James Rochon, Mary L. Uhrich, Dennis T. Villareal, Sai Krupa Das, Luigi Fontana, Manjushri Bhapkar, Corby K. Martin, Leanne M. Redman, Paul J. Fuss, Susan B. Roberts, and William E. Kraus

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BMI-for-age graphs with severe obesity percentile curves: Tools for plotting cross-sectional and longitudinal youth BMI data, Susan B. Racette, Liyang Yu, Nicholas C. DuPont, and B. Ruth Clark

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Recommendations for the clinical management of patients receiving macitentan for pulmonary arterial hypertension (PAH): A Delphi consensus document, Franck F Rahaghi, Murali M Chakinala, and et al

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Post-traumatic osteoarthritis in mice following mechanical injury to the synovial joint, Muhammad Farooq Rai, Xin Duan, James D. Quirk, Nilsson Holguin, Eric J. Schmidt, Nobuaki Chinzei, Matthew J. Silva, and Linda J. Sandell

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Non-invasive aerosol delivery and transport of gold nanoparticles to the brain, Ramesh Raliya, Debajit Saha, Tandeep S. Chadha, Baranidharan Raman, and Pratim Biswas

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Complete genome sequence of BK polyomavirus subtype Ib-1 detected in a kidney transplant patient with BK viremia using shotgun sequencing, Ravi Ranjan, Asha Rani, Daniel C. Brennan, Patricia W. Finn, and David L. Perkins

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Loss of Navβ4-mediated regulation of sodium currents in adult Purkinje neurons disrupts firing and impairs motor coordination and balance, Joseph L. Ransdell, Edward Dranoff, Brandon Lau, Wan-Lin Lo, David L. Donermeyer, Paul M. Allen, and Jeanne M. Nerbonne

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Intensity modulated radiation therapy for squamous cell carcinoma of the vulva: Treatment technique and outcomes, Yuan James Rao, Anupama Chundury, Julie K. Schwarz, Comron Hassanzadeh, Todd DeWees, Daniel Mullen, Matthew A. Powell, David G. Mutch, and Perry W. Grigsby

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Epidemiology and outcomes of vertebral artery injury in 16582 cervical spine surgery patients: An AOSpine North America multicenter study, Wilson Z. Ray and et al.

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Pacritinib to inhibit JAK/STAT signaling in refractory metastatic colon and rectal cancer, Thomas Regenbogen, Ling Chen, Kathryn Trinkaus, Andrea Wang-Gillam, Benjamin R. Tan, Manik Amin, Katrina S. Pedersen, Haeseong Park, Rama Suresh, Kian-Huat Lim, Emily Ratchford, Amberly Brown, and A Craig Lockhart

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AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort, Samuel W. Reinhardt, Andrej Spec, Johanna Melendez, Andrea Alonzo Cordon, Ian Ross, William G. Powderly, and Carlos Mejia Villatoro

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Structured illumination diffuse optical tomography for noninvasive functional neuroimaging in mice, Matthew D. Reisman, Zachary E. Markow, Adam Q. Bauer, and Joseph P. Culver

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Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the KATP channel, Maria S. Remedi, Jonathan B. Friedman, and Colin G. Nichols

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Pediatric anti-N-methyl-D-aspartate receptor encephalitis: A review with pooled analysis and critical care emphasis, Kenneth E. Remy, Jason W. Custer, Joshua Cappell, Cortney B. Foster, Nan A. Garber, L. Kyle Walker, Liliana Simon, and Dayanand Bagdure

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Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients, Nicholas Rensing, David H. Gutmann, Michael Wong, and et al

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Comparing external ventricular drains-related ventriculitis surveillance definitions, Maria M. Reyes, Satish Munigala, Emily L. Church, Tobias B. Kulik, Salah G. Keyrouz, Gregory J. Zipfel, and David K. Warren

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Interaction between the FTO gene, body mass index and depression: Meta-analysis of 13701 individuals, John Rice and et al

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Research priorities in limb and task-specific dystonias, Sarah Pirio Richardson, Eckart Altenmüller, Katharine Alter, Ron L. Alterman, Robert Chen, Steven Frucht, Shinichi Furuya, Joseph Jankovic, H.A. Jinnah, Teresa J. Kimberley, Codrin Lungu, Joel S. Perlmutter, Cecilia N. Prudente, and Mark Hallett

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ALX receptor ligands define a biochemical endotype for severe asthma, Isabell Ricklefs, Mario Castro, Andrea M. Coverstone, and et al

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IL-15 sustains IL-7R-independent ILC2 and ILC3 development, Michelle L. Robinette, Jennifer K. Bando, Wilbur Song, Tyler K. Ulland, Susan Gilfillan, and Marco Colonna

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The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans, Lloyd S. Robinson, Warren G. Lewis, and Amanda L. Lewis

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Viability and tissue quality of cartilage flaps from patients with femoroacetabular hip impingement: A matched-control comparison, Francisco Rodriguez-Fontan, Karin A. Payne, Jorge Chahla, Omer Mei-Dan, Abigail Richards, Soshi Uchida, and Cecilia Pascual-Garrido

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Preclinical Alzheimer's disease and longitudinal driving decline, Catherine M. Roe, Ganesh M. Babulal, Denise M. Head, Sarah H. Stout, Elizabeth K. Vernon, Nupur Ghoshal, Peggy P. Barco, Ann Johnson, Rebecca Fierberg, M. Scot Fague, Chengjie Xiong, Elizabeth A. Grant, David M. Holtzman, Tammie L.S. Benzinger, Anne M. Fagan, David B. Carr, John C. Morris, and et al

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Relationships between consumption of ultra-processed foods, gestational weight gain and neonatal outcomes in a sample of US pregnant women, Karthik W. Rohatgi, Rachel A. Tinius, W. Todd Cade, Euridice Martinez Steele, Alison G. Cahill, and Diana C. Parra

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On the role of the corpus callosum in interhemispheric functional connectivity in humans, Jarod L. Roland, Abraham Z. Snyder, Carl D. Hacker, Anish Mitra, Joshua S. Shimony, David D. Limbrick, Marcus E. Raichle, Matthew D. Smyth, and Eric C. Leuthardt

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Genome sequence of Christensenella minuta DSM 22607T, Bruce A. Rosa, Kymberlie Hallsworth-Pepin, John Martin, Aye Wollam, and Makedonka Mitreva

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Crx-L253X mutation produces dominant photoreceptor defects in TVRM65 mice, Philip A. Ruzycki, Courtney D. Linne, Anne K. Hennig, and Shiming Chen

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Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology, Jason W. Sahl, Jeticia R. Sistrunk, Nabilah Ibnat Baby, Yasmin Begum, Qingwei Luo, Alaullah Sheikh, Firdausi Qadri, James M. Fleckenstein, and David A. Rasko

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Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1), Monica Sala-Rabanal, Zeynep Yurtsever, Kayla N. Berry, Colin G. Nichols, and Tom J. Brett

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Divergent modulation of nociception by glutamatergic and GABAergic neuronal subpopulations in the periaqueductal gray, Vijay K. Samineni, Jose G. Grajales-Reyes, Bryan A. Copits, Daniel E. O'Brien, Sarah L. Trigg, Adrian M. Gomez, Michael R. Bruchas, and Robert W. Gereau IV

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Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain, Vijay K. Samineni, Aaron D. Mickle, Jangyeol Yoon, Jose G. Grajales-Reyes, Melanie Y. Pullen, Kaitlyn E. Crawford, Kyung Nim Noh, Graydon B. Gereau, Sherri K. Vogt, H. Henry Lai, John A. Rogers, and Robert W. Gereau IV

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Biologic therapy in esophageal and gastric malignancies: Current therapies and future directions, Pamela Samson and A. Craig Lockhart

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Whole genome sequencing-based mapping and candidate identification of mutations from fixed zebrafish tissue, Nicholas E. Sanchez, Breanne L. Harty, Thomas O'Reilly-Pol, Sarah D. Ackerman, Amy L. Herbert, Melanie Holmgren, Stephen L. Johnson, Ryan S. Gray, and Kelly R. Monk

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Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors, Savita Sankar, Ethan Patterson, Emily M. Lewis, Laura E. Waller, Caili Tong, Joshua Dearborn, David Wozniak, Joshua B. Rubin, and Kristen L. Kroll

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Trojan horse transit contributes to blood-brain barrier crossing of a eukaryotic pathogen, Felipe H. Santiago-Tirado, Michael D. Onken, John A. Cooper, Robyn S. Klein, and Tamara L. Doering

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Circulating resistin levels and risk of multiple myeloma in three prospective cohorts, Loredana Santo, Lauren R. Teras, Graham G. Giles, Stephanie J. Weinstein, Demetrius Albanes, Ye Wang, Ruth M. Pfeiffer, Qing Lan, Nathaniel Rothman, Brenda M. Birmann, Graham A. Colditz, Michael N. Pollak, Mark P. Purdue, and Jonathan N. Hofmann

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The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones, Shinya Sato, Rikard Frederiksen, M. Carter Cornwall, and Vladimir J. Kefalov

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miR-16 and miR-103 impact 5-HT4 receptor signalling and correlate with symptom profile in irritable bowel syndrome, Gregory Sayuk and et al

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Comparison of symptoms, healthcare utilization, and treatment in diagnosed and undiagnosed individuals with diarrhea-predominant irritable bowel syndrome, Gregory S. Sayuk, Ray Wolf, and Lin Chang

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WormBase 2017: Molting into a new stage, Tim Schedl and et al

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Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13, Stephanie L. Scherer, Matthew D. Cain, Stanley M. Kanal, Kevin M. Kaltenbronn, and Kendall J. Blumer

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Modeling complex patterns of differential DNA methylation that associate with gene expression changes, Christopher E. Schlosberg, Nathan D. VanderKraats, and John R. Edwards

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Randomised controlled trial of Lactobacillus rhamnosus (LGG) versus placebo in children presenting to the emergency department with acute gastroenteritis: The PECARN probiotic study protocol, David Schnadower, Phillip I. Tarr, Feng Gao, and et al

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Changes of ovarian microRNA profile in long-living Ames dwarf mice during aging, Augusto Schneider, Scot J. Matkovich, Berta Victoria, Lina Spinel, Andrzsj Bartke, Pawel Golusinski, and Michal M. Masternak

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Infections in hematopoietic cell transplant recipients: Results from the Organ Transplant Infection Project, a multicenter, prospective, cohort study, Mindy G. Schuster, Angela A. Cleveland, Erik R. Dubberke, Carol A. Kauffman, Robin K. Avery, Shahid Husain, David L. Paterson, Fernanda P. Silveira, Tom M. Chiller, Kaitlin Benedict, Kathleen Murphy, and Peter G. Pappas

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Ca2+-permeable AMPARs mediate glutamatergic transmission and excitotoxic damage at the hair cell ribbon synapse, Joy Y. Sebe, Soyoun Cho, Lavinia Sheets, Mark A. Rutherford, Henrique von Gersdorff, and David W. Raible

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Using clinical scenarios to understand preventability of Clostridium difficile infections by inpatient antibiotic stewardship programs, Jessica Seidelman, Kristen V. Dicks, Michael J. Durkin, Arthur W. Baker, Rebekah W. Moehring, Deverick J. Anderson, Daniel J. Sexton, Luke F. Chen, and Sarah S. Lewis

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Environmental enteric dysfunction is associated with carnitine deficiency and altered fatty acid oxidation, Richard D. Semba, Indi Trehan, Ximin Li, Ruin Moaddel, M. Isabel Ordiz, Kenneth M. Maleta, Klaus Kraemer, Michelle Shardell, Luigi Ferrucci, and Mark Manary

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Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis, Ismail Sergin, Trent D. Evans, Xiangyu Zhang, Somashubhra Bhattacharya, Carl J. Stokes, Eric Song, Sahl Ali, Babak Dehestani, Karyn B. Holloway, Paul S. Micevych, Ali Javaheri, Jan R. Crowley, Andrea Ballabio, Joel D. Schilling, Slava Epelman, Conrad C. Weihl, Abhinav Diwan, Daping Fan, Mohamed A. Zayed, and Babak Razani

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Cancer-associated fibroblasts support vascular growth through mechanical force, Mary Kathryn Sewell-Loftin, Samantha Van Hove Bayer, Elizabeth Crist, Taylor Hughes, Sofia M. Joison, Gregory D. Longmore, and Steven C. George

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Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer, Neel Shah, Ping Wang, John Wongvipat, Wouter R. Karthaus, Wassim Abida, Joshua Armenia, Shira Rockowitz, Yotam Drier, Bradley E. Bernstein, Henry W. Long, Matthew L. Freedman, Vivek K. Arora, Deyou Zheng, and Charles L. Sawyers

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Sclerostin antibody treatment enhances rotator cuff tendon-to-bone healing in an animal model, Shivam A. Shah, Ioannis Kormpakis, Necat Havlioglu, Michael S. Ominsky, Leesa M. Galatz, and Stavros Thomopoulos

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Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions, Alaullah Sheikh, Rasheduzzaman Rashu, Yasmin Ara Begum, F. Matthew Kuhlman, Matthew A. Ciorba, Scott J. Hultgren, Firdausi Qadri, and James M. Fleckenstein

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DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism, Jie Shen, Cuicui Wang, Daofeng Li, Taotao Xu, Jason Myers, John M. Ashton, Ting Wang, Michael J. Zuscik, Audrey McAlinden, and Regis J. O'Keefe

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Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome, Cara Lunn Shirai, Brian S. White, Manorama Tripathi, Roberto Tapia, James N. Ley, Matthew Ndonwi, Sanghyun Kim, Jin Shao, Alexa Carver, Borja Saez, Robert S. Fulton, Catrina Fronick, Michelle O’Laughlin, Chandraiah Lagisetti, Thomas R. Webb, Timothy A. Graubert, and Matthew J. Walter

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Hedgehog signaling via Gli2 prevents obesity induced by high-fat diet in adult mice, Yu Shi and Fanxin Long

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Effects of vitrectomy and lensectomy on older rhesus macaques: Oxygen distribution, antioxidant status, and aqueous humor dynamics, Carla J. Siegried, Ying-Bo Shui, Baohe Tian, Michael Nork, Gregg A. Heatley, and Paul L. Kaufman

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A full lifespan model of vertebrate lens growth, Hrvoje Šikić, Yanrong Shi, Snježana Lubura, and Steven Bassnett

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Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation, Saul S. Siller, Himanshu Sharma, Shuai Li, June Yang, Yong Zhang, Michael J. Holtzman, Wipawee Winuthayanon, Holly Colognato, Bernadette C. Holdener, Feng-Qian Li, and Ken-Ichi Takemaru

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Use of the instantaneous wave-free ratio or fractional flow reserve in PCI, J. Singh and et al

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Optimizing veteran-centered prostate cancer survivorship care: Study protocol for a randomized controlled trial, Ted A. Skolarus, Tabitha Metreger, Soohyun Hwang, Hyungjin Myra Kim, Robert L. Grubb III, Jeffrey R. Gingrich, and Sarah T. Hawley

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Contralateral inhibition of click- and chirp-evoked human compound action potentials, Spencer B. Smith, Jeffery T. Lichtenhan, and Barbara K. Cone

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Cannabis and depression: A twin model approach to co-morbidity, M. Smolkina, K. I. Morley, F. Rijsdijk, A. Agrawal, J. E. Bergin, E. C. Nelson, D. Statham, N. G. Martin, and M. T. Lynskey

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Digital ischemia and necrosis: A rarely described complication of gemcitabine in pancreatic adenocarcinoma, Eiichiro So, Zachary D Crees, Danielle Crites, and Andrea Wang-Gillam

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The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation, Anne C. Solga, Joseph A. Toonen, Yuan Pan, Patrick J. Cimino, Yu Ma, Guillaume A. Castillon, Scott M. Gianino, Mark H. Ellisman, Da Yong Lee, and David H. Gutmann

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Personality profile and short-term treatment outcome in patients with alcohol dependence: A study from South India, Soundarya Soundararajan, Gitanjali Narayanan, Arpana Agrawal, and Pratima Murthy

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Relation between age at first alcohol drink and adult life drinking patterns in alcohol-dependent patients, Soundarya Soundararajan, Gitanjali Narayanan, Arpana Agrawal, Dorairaj Prabhakaran, and Pratima Murthy

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Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuits, Skylar M. Spangler and Michael R. Bruchas

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Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin, Mary Speir, Adam Vogrin, Azadeh Seidi, Gilu Abraham, Stephane Hunot, Qingqing Han, Gerald W. Dorn II, Seth L. Masters, Richard A. Flavell, James E. Vince, and Thomas Naderer

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RNA interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis, Deepa Srikanta, Camaron R. Hole, Matthew Williams, Shabaana A. Khader, and Tamara L. Doering

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Protocol for the home hazards removal program (HARP) study: A pragmatic, randomized clinical trial and implementation study, Susan Stark, Emily Somerville, Marian Keglovits, Jane Conte, Melody Li, Yi-Ling Hu, and Yan Yan

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Practice patterns and outcomes associated with early sedation depth in mechanically ventilated patients: A systematic review protocol, Robert J. Stephens, Matthew R. Dettmer, Brian W. Roberts, Susan A. Fowler, and Brian M. Fuller

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Systematic evaluation of pleiotropy identifies 6 further loci associated with coronary artery disease, Nathan O. Stitziel, Christian Hengstenberg, and et al

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MicroRNAs in the etiology of colorectal cancer: Pathways and clinical implications, Ashlee M. Strubberg and Blair B. Madison

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Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy, Hani Y. Suleiman, Robyn Roth, Sanjay Jain, John E. Heuser, Andrey S. Shaw, and Jeffrey H. Miner

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Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus, Vasavi Sundaram, Mayank N.K. Choudhary, Erica Pehrsson, Xiaoyun Xing, Christopher Fiore, Manishi Pandey, Brett Maricque, Methma Udawatta, Duc Ngo, Yujie Chen, Asia Paguntalan, Tammy Ray, Ava Hughes, Barak A. Cohen, and Ting Wang

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Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits, Yun Ju Sung, D.C. Rao, Treva Rice, Andrew C. Heath, Pamela A.F. Madden, Mary F. Feitosa, Llilda Barata, Jacek Czajkowski, Ingrid B. Borecki, and et al

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Low to moderate relationships between gait and postural responses in Parkinson disease, Ellen N. Sutter, Katie J. Seidler, Ryan P. Duncan, Gammon M. Earhart, and Marie E. McNeely