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Submissions from 2022

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External validation of a mammography-derived AI-based risk model in a U.S. breast cancer screening cohort of White and Black women, Aimilia Gastounioti, Mikael Eriksson, Eric A Cohen, Walter Mankowski, Lauren Pantalone, Sarah Ehsan, Anne Marie McCarthy, Despina Kontos, Per Hall, and Emily F Conant

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Help is available: Supporting mental wellness through peer health navigation with young black men who have sex with men with HIV, Donald R Gerke, Jeff Glotfelty, Maria Freshman, Julia Schlueter, Alex Ochs, and Katie Plax

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Public health information seeking, trust, and COVID-19 prevention behaviors: Cross-sectional study, Emmanuel Kwabena Tetteh, Todd Combs, Elvin Hsing Geng, and Virginia Ruth McKay

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Stroke genetics informs drug discovery and risk prediction across ancestries, Aniket Mishra, Carlos Cruchaga, and et al.

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Multicenter, randomized trial of a bionic pancreas in type 1 diabetes, Steven J Russell, Janet B McGill, Maamoun Salam, Julie M Silverstein, Samantha Adamson, Andrea Cedeno, and et al.

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Proteomic and phosphoproteomic landscapes of acute myeloid leukemia, Michael H Kramer, Qiang Zhang, Robert Sprung, Ryan B Day, Petra Erdmann-Gilmore, Yang Li, Ziheng Xu, Nichole M Helton, Daniel R George, Yiling Mi, Peter Westervelt, Jacqueline E Payton, Sai M Ramakrishnan, Christopher A Miller, Daniel C Link, John F DiPersio, Matthew J Walter, R Reid Townsend, and Timothy J Ley

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The prognostic value of early measures of the ventilatory ratio in the ARDS ROSE trial, Ana Carolina Costa Monteiro, Sitaram Vangala, Katherine D Wick, Kevin L Delucchi, Emily R Siegel, B Taylor Thompson, Kathleen D Liu, Anil Sapru, Pratik Sinha, Michael A Matthay, and NHLBI PETAL Network

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A case of persistent human pegivirus infection in two separate pregnancies of a woman, Mathieu Garand, Susie S Y Huang, Lisa S Goessling, Donna A Santillan, Mark K Santillan, Anoop Brar, Todd N Wylie, Kristine M Wylie, and Pirooz Eghtesady

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The effect of A1 and A2 reactive astrocyte expression on hydrocephalus shunt failure, Fatemeh Khodadadei, Rooshan Arshad, Diego M Morales, Jacob Gluski, Neena I Marupudi, James P McAllister 2nd, David D Limbrick Jr., and Carolyn A Harris

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A retrospective study on use of palliative care for patients with alcohol related end stage liver disease in United States, Kamesh Gupta, Bandhul Hans, Ahmad Khan, Syed Hamza Sohail, Devika Kapuria, and Chris Chang

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Blood-brain barrier opening in a large animal model using closed-loop microbubble cavitation-based feedback control of focused ultrasound sonication, Chih-Yen Chien, Lu Xu, Christopher Pham Pacia, Yimei Yue, and Hong Chen

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Meeting the challenges of myocarditis: New opportunities for prevention, detection, and intervention-a report from the 2021 National Heart, Lung, and Blood Institute workshop, Daniela Čiháková, Yang Shi, Bishow Adhikari, W Patricia Bandettini, Madeleine W Cunningham, Narasimhan Danthi, Matthias G Friedrich, Peter Liu, Lisa Schwartz Longacre, Douglas L Mann, Filip K Swirski, W H Wilson Tang, Guofei Zhou, Leslie T Cooper Jr., and Workshop Speakers

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The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems, Keren Lasker, Steven Boeynaems, Vinson Lam, Daniel Scholl, Emma Stainton, Adam Briner, Maarten Jacquemyn, Dirk Daelemans, Ashok Deniz, Elizabeth Villa, Alex S Holehouse, Aaron D Gitler, and Lucy Shapiro

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Trending anti-E7 serology predicts mortality and recurrence of HPV-associated cancers of the oropharynx, Luke Johnson, Dat T Ha, Melissa B Hall, Gregory Shoemaker, Paul A Bevins, John Strickley, Shadmehr Demehri, Rebecca A Redman, and Joongho Joh

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Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue-resident T cells that drive synapse elimination, Sarah F Rosen, Allison L Soung, Wei Yang, Shenjian Ai, Marlene Kanmogne, Veronica A Davé, Maxim Artyomov, Jeffrey A Magee, and Robyn S Klein

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Islet primary cilia motility controls insulin secretion, Jung Hoon Cho, Zipeng A Li, Lifei Zhu, Brian D Muegge, Henry F Roseman, Eun Young Lee, Toby Utterback, Louis G Woodhams, Philip V Bayly, and Jing W Hughes

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Leading the way: Competencies of leadership to prevent mis-implementation of public health programs, Sarah Moreland-Russell, Louise Farah Saliba, Emily Rodriguez Weno, Romario Smith, Margaret Padek, and Ross C Brownson

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Non-sedative cortical EEG signatures of allopregnanolone and functional comparators, Peter M Lambert, Richard Ni, Ann Benz, Nicholas R Rensing, Michael Wong, Charles F Zorumski, and Steven Mennerick

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Quantification of ovarian lesion and fallopian tube vasculature using optical-resolution photoacoustic microscopy, Xiandong Leng, Sitai Kou, Yixiao Lin, Andrea R Hagemann, Ian S Hagemann, Premal H Thaker, Lindsay M Kuroki, Carolyn K McCourt, David G Mutch, Cary Siegel, Matthew A Powell, and Quing Zhu

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Efficacy of a smartphone-based care support programme in improving post-traumatic stress in families with childhood cancer: Protocol of a randomised controlled trial, Jun Ma, Han-Zhu Qian, Yueyang Peng, Yali Xiang, Minghua Yang, Jessica Hahne, and Can Gu

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Long-term neurologic outcomes of COVID-19, Evan Xu, Yan Xie, and Ziyad Al-Aly

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Multidimensional analysis and therapeutic development using patient iPSC-derived disease models of Wolfram syndrome, Rie Asada Kitamura, Kristina G. Maxwell, Kelly Kries, Cris M. Brown, Punn Augsornworawat, Jeffrey R Millman, Fumihiko Urano, and et al

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Predictive value of the advanced lipoprotein profile and glycated proteins on diabetic retinopathy, Josep Julve, Joana Rossell, Eudald Correig, Marina Idalia Rojo-Lopez, Nuria Amigó, Marta Hernández, Alicia Traveset, Marc Carbonell, Nuria Alonso, Didac Mauricio, and Esmeralda Castelblanco

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TBX21 methylation as a potential regulator of immune suppression in CMS1 subtype colorectal cancer, Yuanyuan Shen, Yulia I Nussbaum, Yariswamy Manjunath, Justin J Hummel, Matthew A Ciorba, Wesley C Warren, Jussuf T Kaifi, Christos Papageorgiou, Rene Cortese, Chi-Ren Shyu, and Jonathan B Mitchem

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Trial of antisense oligonucleotide tofersen for SOD1 ALS, Timothy M Miller, Robert C Bucelli, and et al.

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High prevalence of chronic viral hepatitis B and C in Minnesota Somalis contributes to rising hepatocellular carcinoma incidence, Essa A Mohamed, Joyce E Balls-Berry, and et al.

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Leadership experiences of internal medicine residents: A needs assessment for leadership curricula, Maureen D Lyons, Julie Oyler, Katherine Iossi, and Sarah Merriam

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Current understanding of osteoarthritis pathogenesis and relevant new approaches, Liping Tong, Huan Yu, Xingyun Huang, Jie Shen, Guozhi Xiao, Lin Chen, Huaiyu Wang, Lianping Xing, and Di Chen

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Effect of the Tokyo 2020 Summer Olympic Games on COVID-19 incidence in Japan: A synthetic control approach, Daisuke Yoneoka, Akifumi Eguchi, Kentato Fukumoto, Takayuki Kawashima, Yuta Tanoue, Takahiro Tabuchi, Hiroaki Miyata, Cyrus Ghaznavi, Kenji Shibuya, and Shuhei Nomura

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Laser stimulation of the skin for quantitative study of decision-making and motivation, Julia Pai, Takaya Ogasawara, Ethan S Bromberg-Martin, Kei Ogasawara, Robert W Gereau, and Ilya E Monosov

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Regulation of human cortical interneuron development by the chromatin remodeling protein CHD2, E M A Lewis, G Chapman, K Kaushik, J Determan, I Antony, K Meganathan, M Narasimhan, P Gontarz, B Zhang, and K L Kroll

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A protocol to induce systemic autophagy and increase energy metabolism in mice using PEGylated arginine deiminase, Yiming Zhang and Brian J. DeBosch

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Contrast-enhanced microCT evaluation of degeneration following partial and full width injuries to the mouse lumbar intervertebral disc, Remy E Walk, Hong Joo Moon, Simon Y Tang, and Munish C Gupta

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Generation of dual-gRNA library for combinatorial CRISPR screening of synthetic lethal gene pairs, Shan Tang, Xue Wu, Jinghui Liu, Qiongsi Zhang, Xinyi Wang, Shuai Shao, Birkan Gokbag, Kunjie Fan, Xiaoqi Liu, Fuhai Li, Lijun Cheng, and Lang Li

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Economic evaluation of ultrasound-guided central venous catheter confirmation vs chest radiography in critically ill patients: A labor cost model, Enyo A. Ablordeppey, Adam M. Koenig, Abigail R. Barker, Emily E. Hernandez, Suzanne M. Simkovich, James G. Krings, Derek S. Brown, and Richard T. Griffey

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Ehrlich tumor induces TRPV1-dependent evoked and non-evoked pain-like behavior in mice, Mariana M Bertozzi, Telma Saraiva-Santos, Tiago H Zaninelli, Felipe A Pinho-Ribeiro, Victor Fattori, Larissa Staurengo-Ferrari, Camila R Ferraz, Talita P Domiciano, Cassia Calixto-Campos, Sergio M Borghi, Ana C Zarpelon, Thiago M Cunha, Rubia Casagrande, and Waldiceu A Verri

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Identifying moderating factors during the preschool period in the development of borderline personality disorder: A prospective longitudinal analysis, Kiran Boone, Alecia C Vogel, Rebecca Tillman, Amanda J Wright, Deanna M Barch, Joan L Luby, and Diana J Whalen

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Intracellular connections between basal bodies promote the coordinated behavior of motile cilia, Adam W J Soh, Louis G Woodhams, Anthony D Junker, Cassidy M Enloe, Benjamin E Noren, Adam Harned, Christopher J Westlake, Kedar Narayan, John S Oakey, Philip V Bayly, and Chad G Pearson

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Systemic chemotherapies retain antitumor activity in desmoid tumors independent of specific mutations in CTNNB1 or APC: A multi-institutional retrospective study, Michael J Nathenson, Katharina Feister, and Et al

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Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19, Katherine D Wick, Pratik Sinha, and et al.

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Translational design for limited resource settings as demonstrated by Vent-Lock, a 3D-printed ventilator multiplexer, Helen Xun, Broc Burke, Michael Montana, Michael Talcott, Margaret Frisella, Bradley S Kushner, Justin M Sacks, and et al.

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American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis for patients with COVID-19: March 2022 update on the use of anticoagulation in critically ill patients, Adam Cuker, Kristen M Sanfilippo, and et al

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American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: January 2022 update on the use of therapeutic-intensity anticoagulation in acutely ill patients, Adam Cuker, Kristen M Sanfilippo, and et al

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Innexin function dictates the spatial relationship between distal somatic cells in the Caenorhabditis elegans gonad without impacting the germline stem cell pool, Theadora Tolkin, Ariz Mohammad, Todd A Starich, Ken C Q Nguyen, David H Hall, Tim Schedl, E Jane Albert Hubbard, and David Greenstein

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The first reported case of a patient with pancreatic cancer treated with cone beam computed tomography-guided stereotactic adaptive radiotherapy (CT-STAR), Minsol Kim, Joshua P Schiff, Alex Price, Eric Laugeman, Pamela P Samson, Hyun Kim, Shahed N Badiyan, and Lauren E Henke

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Transplant outcomes after CPX-351 vs 7 + 3 in older adults with newly diagnosed high-risk and/or secondary AML, Geoffrey L Uy, Laura F Newell, Tara L Lin, Stuart L Goldberg, Matthew J Wieduwilt, Robert J Ryan, Stefan Faderl, and Jeffrey E Lancet

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Implementation of a provider-focused intervention for maximizing human papillomavirus (HPV) vaccine uptake in young cancer survivors receiving follow-up care in pediatric oncology practices: Protocol for a cluster-randomized trial of the HPV PROTECT intervention, Wendy Landier, Smita Bhatia, Joshua S Richman, Paula D Campos Gonzalez, Brooke Cherven, Veronica Chollette, Jamie Aye, Sharon M Castellino, Maria M Gramatges, Susan Lindemulder, Thomas B Russell, Lucie M Turcotte, Graham A Colditz, Melissa B Gilkey, and James L Klosky

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Septic cardiomyopathy: From pathophysiology to the clinical setting, Federico Carbone, Luca Liberale, Alberto Preda, Thomas Hellmut Schindler, and Fabrizio Montecucco

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A case study of adapting a health insurance decision intervention from trial into routine cancer care, Miles E Charles, Lindsay M Kuroki, Ana A Baumann, Rachel G Tabak, Aimee James, Krista Cooksey, and Mary C Politi

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Tissue rotation of the Xenopus anterior–posterior neural axis reveals profound but transient plasticity at the mid-gastrula stage, Lyuba Bolkhovitinov, Bryan T Weselman, Gladys A Shaw, Chen Dong, Janhavi Giribhattanavar, and Margaret S Saha

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IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2, Pavel A Nikitin, Suzanne M Scheaffer, Michael S Diamond, and Et al

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The Core Rehabilitation Outcome Set for Single-Sided Deafness (CROSSSD) study: International consensus on outcome measures for trials of interventions for adults with single-sided deafness, Roulla Katiri, Deborah A Hall, Derek J Hoare, Kathryn Fackrell, Adele Horobin, Nicholas Hogan, Nóra Buggy, Paul H Van de Heyning, Jill B Firszt, Iain A Bruce, Pádraig T Kitterick, and Core Rehabilitation Outcome Set for Single-Sided Deafness (CROSSSD) initiative

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The IFN-γ receptor promotes immune dysregulation and disease in STING gain-of-function mice, W. Alexander Stinson, Cathrine A. Miner, Fang R. Zhao, Annena Jane Lundgren, Subhajit Poddar, and Jonathan J. Miner

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The role of electroencephalography in the prognostication of clinical outcomes in critically ill children: A review, Carley A Gilman, Courtney J Wusthoff, and Réjean M Guerriero

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Validation of blood-based transcriptomic circadian phenotyping in older adults, S Kendall Smith, Peter Tran, Katherine A Madden, Jill Boyd, Rosemary Braun, Erik S Musiek, and Yo-El S Ju

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Effectiveness and minimum effective dose of app-based mobile health interventions for anxiety and depression symptom reduction: Systematic review and meta-analysis, Sheng-Chieh Lu, Mindy Xu, Mei Wang, Angela Hardi, Abby L Cheng, Su-Hsin Chang, and Po-Yin Yen

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Feasibility and sensitivity study of radiomic features in photoacoustic imaging of patient-derived xenografts, Lorena Escudero Sanchez, Emma Brown, Leonardo Rundo, Stephan Ursprung, Evis Sala, Sarah E Bohndiek, and Ignacio Xavier Partarrieu

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Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention, Zhe Wang, Mary F. Feitosa, and et al

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Idiopathic ventricular fibrillation in a previously healthy recreational athlete, Caleb Norton, Daniel H Cooper, Gregory Ewald, and Mustafa Husaini

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Concentrated incarceration and the public-housing-to-prison pipeline in New York City neighborhoods, Jay Holder, Ivan Calaff, Brett Maricque, and Van C Tran

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Issues with variability in electronic health record data about race and ethnicity: Descriptive analysis of the National COVID Cohort Collaborative Data Enclave, Lily Cook, Juan Espinoza, Nicole G Weiskopf, Nisha Mathews, David A Dorr, Kelly L Gonzales, Adam Wilcox, Charisse Madlock-Brown, and N3C Consoritium

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Killer-cell immunoglobulin-like receptor diversity in an admixed South American population, Marlon Castrillon, Nancy D Marin, Amado J Karduss-Urueta, Sonia Y Velasquez, and Cristiam M Alvarez

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Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression, Parker C Wilson, Yoshiharu Muto, Haojia Wu, Anil Karihaloo, Sushrut S Waikar, and Benjamin D Humphreys

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Novel antiinflammatory biologics shaped by parasite-host coevolution, Stephanie M Ryan, Makedonka Mitreva, and Et al

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The microbial one-hit wonder, Brigida A. Rusconi and Rodney D. Newberry

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An ex vivo culture model of kidney podocyte injury reveals mechanosensitive, synaptopodin-templating, sarcomere-like structures, Shumeng Jiang, Farid Alisafaei, Yin-Yuan Huang, Yuan Hong, Xiangjun Peng, Chengqing Qu, Pongpratch Puapatanakul, Sanjay Jain, Jeffrey H Miner, Guy M Genin, and Hani Y Suleiman

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Exit rates of accountable care organizations that serve high proportions of beneficiaries of racial and ethnic minority groups, Sunny C Lin, Karen E Joynt Maddox, Andrew M Ryan, Nicholas Moloci, Addison Shay, and John Malcolm Hollingsworth

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Genome scanning of behavioral selection in a canine olfactory detection breeding cohort, Alexander W Eyre, Isain Zapata, Elizabeth Hare, Katharine M N Lee, Claire Bellis, Jennifer L Essler, Cynthia M Otto, James A Serpell, and Carlos E Alvarez

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LRP1 is a neuronal receptor for α-synuclein uptake and spread, Kai Chen, David M Holtzman, and et al.

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SMYD3 impedes small cell lung cancer sensitivity to alkylation damage through RNF113A methylation-phosphorylation cross-talk, Valentina Lukinović, Clement Oyeniran, Ning Tsao, Joshua R Brickner, Rebecca Rodell, Nima Mosammaparast, and Et al

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The metabolism of human soluble Amyloid Precursor Protein isoforms is quantifiable by a stable isotope labeling-tandem mass spectrometry method, Justyna A Dobrowolska Zakaria, Randall J Bateman, Monika Lysakowska, Ammaarah Khatri, Dinorah Jean-Gilles, Matthew E Kennedy, and Robert Vassar

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Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back viral genome population followed by selection, Sébastien A Felt, Emna Achouri, Sydney R Faber, and Carolina B López

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Adolescent and young adult preferences for financial incentives to support adherence to antiretroviral therapy in Kenya: A mixed methods study, Ingrid Eshun-Wilson, Eliud Akama, Fridah Adhiambo, Zachary Kwena, Bertha Oketch, Sarah Obatsa, Sarah Iguna, Jayne L Kulzer, James Nyanga, Everlyne Nyandieka, Ally Scheve, Elvin H Geng, Elizabeth A Bukusi, and Lisa Abuogi

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A mid-level health manager intervention to promote uptake of isoniazid preventive therapy among people with HIV in Uganda: A cluster randomised trial, Elijah Kakande, Elvin H Geng, and et al.

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A narrative review of irritable bowel syndrome with diarrhea: A primer for primary care providers, Baha Moshiree, Joel J Heidelbaugh, and Gregory S Sayuk

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An evaluation of patient-reported outcomes in sickle cell disease within a conceptual model., Marsha J Treadwell, Swapandeep Mushiana, Sherif M Badawy, Liliana Preiss, Allison A King, Barbara Kroner, Yumei Chen, Jeffrey Glassberg, Victor Gordeuk, Nirmish Shah, Angela Snyder, Theodore Wun, and Sickle Cell Disease Implementation Consortium (SCDIC)

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An iPS-derived in vitro model of human atrial conduction, Sherri M Biendarra-Tiegs, Sergey Yechikov, Bhupinder Shergill, Brittany Brumback, Kentaro Takahashi, Venktesh S Shirure, Ruth Estelle Gonzalez, Laura Houshmand, Denise Zhong, Kuo-Chan Weng, Jon Silva, Timothy W Smith, Stacey L Rentschler, and Steven C George

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A randomized controlled trial in schools aimed at exploring mechanisms of change of a multifaceted implementation strategy for promoting mental health at the workplace, Lydia Kwak, Anna Toropova, Byron J Powell, Rebecca Lengnick-Hall, Irene Jensen, Gunnar Bergström, Liselotte Schäfer Elinder, Kjerstin Stigmar, Charlotte Wåhlin, and Christina Björklund

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Association of blood-based brain injury biomarker concentrations with outcomes after pediatric cardiac arrest, Ericka L Fink, Stuart Friess, and et al.

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Association of male hypogonadism with risk of hospitalization for COVID-19, Sandeep Dhindsa, Cosette Champion, Ekamjit Deol, Matthew Lui, Robert Campbell, Jennifer Newman, Aparna Yeggalam, Srikanth Nadella, Vaishaliben Ahir, Ekta Shrestha, Thomas Kannampallil, and Abhinav Diwan

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A systematic review of recent and ongoing clinical trials in patients with the neurofibromatoses, Simge Acar, Edwin Nieblas-Bedolla, Amy E Armstrong, and Angela C Hirbe

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Characteristics and patterns of retention in hypertension care in primary care settings from the Hypertension Treatment in Nigeria Program, Jiancheng Ye, Mark D Huffman, and et al.

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Clinical trial data of anti-PD-1/PD-L1 therapy for recurrent or metastatic nasopharyngeal carcinoma: A review, Douglas R Adkins and Robert I. Haddad

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Consensus-based recommendations on priority activities to address acute kidney injury in children: A modified Delphi consensus statement, Stuart L Goldstein, Tara M Neumayr, and et al.

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Coronavirus disease 2019 (COVID-19) vaccination preparedness policies in US hospitals, Susan E Beekmann, Hilary M Babcock, Mark S Rasnake, Thomas R Talbot, and Philip M Polgreen

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Creation and internal validation of a clinical predictive model for fluconazole resistance in patients with Candida bloodstream infection, Adriana M Rauseo, Margaret A Olsen, Dustin Stwalley, Patrick B Mazi, Lindsey Larson, William G Powderly, and Andrej Spec

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Disease burden affects aging brain function, Lori L Beason-Held, Danielle Fournier, Andrea T Shafer, Elisa Fabbri, Yang An, Chiung-Wei Huang, Murat Bilgel, Dean F Wong, Luigi Ferrucci, and Susan M Resnick

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Does social intolerance vary according to cognitive styles, genetic cognitive capacity, or education?, Aino Saarinen, Liisa Keltikangas-Järvinen, Henrik Dobewall, C Robert Cloninger, Ari Ahola-Olli, Terho Lehtimäki, Nina Hutri-Kähönen, Olli Raitakari, Suvi Rovio, and Niklas Ravaja

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Efficacy and safety of ofatumumab in recently diagnosed, treatment-naive patients with multiple sclerosis: Results from ASCLEPIOS I and II, Jutta Gärtner, Stephen L Hauser, Amit Bar-Or, Xavier Montalban, Jeffrey A Cohen, Anne H Cross, Kumaran Deiva, Habib Ganjgahi, Dieter A Häring, Bingbing Li, Ratnakar Pingili, Krishnan Ramanathan, Wendy Su, Roman Willi, Bernd Kieseier, and Ludwig Kappos

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Empirical transmit field bias correction of T1w/T2w myelin maps, Matthew F. Glasser, Timothy S. Coalson, Michael P. Harms, Junqian Xu, Graham L. Baum, Joonas A. Autio, Edward J. Auerbach, Douglas N. Greve, Essa Yacoub, David C. Van Essen, Nicholas A. Bock, and Takuya Hayashi

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Exposure contrasts of pregnant women during the Household Air Pollution Intervention Network randomized controlled trial, Michael Johnson, Lindsay J Underhill, and et al.

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Exposure to World Health Organization's AWaRe antibiotics and isolation of multidrug resistant bacteria: A systematic review and meta-analysis, Giorgia Sulis, Sena Sayood, Shashi Katukoori, Neha Bollam, Ige George, Lauren H. Yaeger, Miguel A. Chavez, Emmanuel Tetteh, Sindhu Yarrabelli, Celine Pulcini, Stephan Harbarth, Dominik Mertz, Mike Sharland, Lorenzo Moja, Benedikt Huttner, and Sumanth Gandra

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First-in-human phase I/II ICONIC trial of the ICOS agonist vopratelimab alone and with nivolumab: ICOS-high CD4 T-cell populations and predictors of response, Timothy A Yap, Russell K Pachynski, Haeseong Park, and Et al

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GAPDH mediates drug resistance and metabolism in Plasmodium falciparum malaria parasites, Andrew J. Jezewski, Ann M. Guggisberg, Dana M. Hodge, Naomi Ghebremichael, Gavin Nicholas John, Lisa K. McLellan, and Audrey Ragan Odom John

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High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios, Marta Byrska-Bishop, Haley J Abel, Allison A Regier, Ira M Hall, and et al.

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Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration, Hirdesh Kumar, John R Jimah, Santosh A Misal, Nichole D Salinas, Michal Fried, Paul H Schlesinger, and Niraj H Tolia

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Lack of VMP1 impairs hepatic lipoprotein secretion and promotes non-alcoholic steatohepatitis, Xiaoxiao Jiang, Yan Xie, Nicholas O Davidson, and et al.

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Living with cervical spinal cord injury during the COVID-19 pandemic: A qualitative study, Elspeth J R Hill, Allison J L'Hotta, Carie R Kennedy, Aimee S James, and Ida K Fox

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Measuring transcription factor binding and gene expression using barcoded self-reporting transposon calling cards and transcriptomes, Matthew Lalli, Allen Yen, Urvashi Thopte, Fengping Dong, Arnav Moudgil, Xuhua Chen, Jeffrey Milbrandt, Joseph D Dougherty, and Robi D Mitra

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Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis, Junhua Xu, Yanfeng Zhong, Haoyang Yin, John Linneman, Yixuan Luo, Sijian Xia, Qinyi Xia, Lei Yang, Xingtao Huang, Kang Kang, Jun Wang, Yanqin Niu, Li Li, and Deming Gou