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Submissions from 2024

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Spatial and amplitude dynamics of neurostimulation: Insights from the acute intrahippocampal kainate seizure mouse model, Thomas J Foutz, Nicholas Rensing, Lirong Han, Dominique M Durand, and Michael Wong

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Stabilizing the proteomes of acute myeloid leukemia cells: Implications for cancer proteomics, Robert W Sprung, Qiang Zhang, Michael H Kramer, Matthew C Christopher, Petra Erdmann-Gilmore, Yiling Mi, James P Malone, Timothy J Ley, and R Reid Townsend

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Stem cell modeling of nervous system tumors, Frank B Furnari, Corina Anastasaki, Shan Bian, Howard A Fine, Tomoyuki Koga, Lu Q Le, Fausto J Rodriguez, and David H Gutmann

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Stereotactic MR-guided on-table adaptive radiation therapy (SMART) for borderline resectable and locally advanced pancreatic cancer: A multi-center, open-label phase 2 study, Michael D Chuong, Hyun Kim, Lauren E Henke, Alex T Price, and et al.

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Structural biases in disordered proteins are prevalent in the cell, David Moses, Karina Guadalupe, Feng Yu, Eduardo Flores, Anthony R Perez, Ralph McAnelly, Nora M Shamoon, Gagandeep Kaur, Estefania Cuevas-Zepeda, Andrea D Merg, Erik W Martin, Alex S Holehouse, and Shahar Sukenik

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Surgically implanted endovascular, microaxial left ventricular assist device: A single institution study, Erin M Schumer, Yun Zhu Bai, Kunal D Kotkar, M Faraz Masood, Akinobu Itoh, Joel D Schilling, Gregory A Ewald, Marci S Damiano, Irene Fischer, Tsuyoshi Kaneko, Ralph J Damiano, and Amit Pawale

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The Bethesda ERCP Skills Assessment Tool (BESAT) can reliably differentiate endoscopists of different experience levels, Kevin Liu, Vladimir Kushnir, and et al.

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The impact of patterns in linkage disequilibrium and sequencing quality on the imprint of balancing selection, Tristan J Hayeck, Yang Li, Timothy L Mosbruger, Jonathan P Bradfield, Adam G Gleason, George Damianos, Grace Tzun-Wen Shaw, Jamie L Duke, Laura K Conlin, Tychele N Turner, Marcelo A Fernández-Viña, Mahdi Sarmady, and Dimitri S Monos

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Top 50 most-cited studies about osteochondritis dissecans, Nicholas D Thomas, Raegan Mahler, Kylie Krombholz, Brendan Williams, Ted Ganley, Jeffrey J Nepple, and Kevin Shea

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"We need a little strength as well": Examining the social context of informal caregivers for Black women with breast cancer, Tess Thompson, Jacquelyn Coats, Merriah Croston, Robert O Motley Jr, Vetta Sanders Thompson, Aimee S James, and LaShaune P Johnson

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Basis of executive functions in fine-grained architecture of cortical and subcortical human brain networks, Moataz Assem, Sneha Shashidhara, Matthew F Glasser, and John Duncan

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Cardiovascular health assessment in routine cancer follow-up in community settings: Survivor risk awareness and perspectives, Kathryn E Weaver, Emily V Dressler, Sydney Smith, Chandylen L Nightingale, Heidi D Klepin, Simon Craddock Lee, Brian J Wells, W Gregory Hundley, Joseph A DeMari, Sarah N Price, and Randi E Foraker

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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase, Stanley C Xie, Eva S Istvan, Daniel E Goldberg, and et al.

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A cataract-causing mutation in the TRPM3 cation channel disrupts calcium dynamics in the lens, Yuefang Zhou, Thomas M Bennett, Philip A Ruzycki, Zhaohua Guo, Yu-Qing Cao, Mohammad Shahidullah, Nicholas A Delamere, and Alan Shiels

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A quick reCAP: Discovering Cryptococcus neoformans capsule mutants, Daphne Boodwa-Ko and Tamara L Doering

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Complement receptor 1 is the human erythrocyte receptor for Plasmodium vivax erythrocyte binding protein, Seong-Kyun Lee, Cécile Crosnier, Paola Carolina Valenzuela-Leon, Brian L P Dizon, John P Atkinson, Jianbing Mu, Gavin J Wright, Eric Calvo, Karthigayan Gunalan, and Louis H Miller

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds, Eike-Christian Wamhoff, James Brett Case, Shilpa Sanapala, Michael S Diamond, and et al.

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Inter- and intra-observer variability of radial-endobronchial ultrasound image interpretation for peripheral pulmonary lesions, Nathaniel Moulton, Daniel B. Abbasi, Danish Ahmad, Nikki E. Burks, Praveen Chenna, Kevin Haas, Andrea Loiselle, Essam Mekhaiel, Mayank R. Pilli, Ali Sadoughi, Brandt Lydon, Tej Patel, and Alexander C. Chen

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Analysis of anemia and iron supplementation among glioblastoma patients reveals sex-biased association between anemia and survival, Ganesh Shenoy, Becky Slagle-Webb, Chachrit Khunsriraksakul, Bhavyata Pandya Shesh, Jingqin Luo, Vladimir Khristov, Nataliya Smith, Alireza Mansouri, Brad E Zacharia, Sheldon Holder, Justin D Lathia, Jill S Barnholtz-Sloan, and James R Connor

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Clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: Pediatric congenital heart disease conditions, Justin R Ryan, David Ballard, and et al.

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Dorsal hippocampus to nucleus accumbens projections drive reinforcement via activation of accumbal dynorphin neurons, Khairunisa Mohamad Ibrahim, Nicolas Massaly, Hye-Jean Yoon, Rossana Sandoval, Allie J Widman, Robert J Heuermann, Sidney Williams, William Post, Sulan Pathiranage, Tania Lintz, Azra Zec, Ashley Park, Robert W Gereau 4th, Jose A Morón, and et al.

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Mosaic loss of Y chromosome is associated with aging and epithelial injury in chronic kidney disease, Parker C Wilson, Amit Verma, Yasuhiro Yoshimura, Yoshiharu Muto, Haikuo Li, Nicole P Malvin, Eryn E Dixon, and Benjamin D Humphreys

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Venovenous extracorporeal membrane oxygenation after cardiac arrest for acute respiratory distress syndrome caused by Legionella: A case report, John C Grotberg, Linda Schulte, Erin Schumer, Mary Sullivan, Kunal Kotkar, Mohammad F Masood, and Amit Pawale

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Reviewing the Clostridioides difficile mouse model: Insights into infection mechanisms, José L Fachi, Marco A R Vinolo, and Marco Colonna

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Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis, Hao Yu, Lilian Antunes, Christina A Gurnett, and et al.

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Tempo and mode of gene expression evolution in the brain across primates, Katherine Rickelton, Trisha M Zintel, Jason Pizzollo, Emily Miller, John J Ely, Mary Ann Raghanti, William D Hopkins, Patrick R Hof, Chet C Sherwood, Amy L Bauernfeind, and Courtney C Babbitt

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GlioPredictor: A deep learning model for identification of high-risk adult IDH-mutant glioma towards adjuvant treatment planning, Shuhua Zheng, Nikhil Rammohan, Timothy Sita, P Troy Teo, Yilin Wu, Maciej Lesniak, Sean Sachdev, and Tarita O Thomas

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Comparative and integrative single cell analysis reveals new insights into the transcriptional immaturity of stem cell-derived β cells, Mason D Schmidt, Matthew Ishahak, Punn Augsornworawat, and Jeffrey R Millman

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Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot, Evan L. Barrios, Drew E. Del Toro, Alexandra Dram, Sandra Meszaros, Sydney Miles, Andrew H. Walton, Anne M. Drewry, Isaiah R. Turnbull, Richard S Hotchkiss, and et al.

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An orally available compound suppresses glucagon hypersecretion and normalizes hyperglycemia in type 1 diabetes, Farzad Asadi, Subhadra C. Gunawardana, Roland E. Dolle, and David W. Piston

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B cells mediate lung ischemia/reperfusion injury by recruiting classical monocytes via synergistic B cell receptor/TLR4 signaling, Khashayar Farahnak, Yun Zhu Bai, Yuhei Yokoyama, Deniz B. Morkan, Zhiyi Liu, Junedh M. Amrute, Alejandro De Filippis Falcon, Yuriko Terada, Fuyi Liao, Wenjun Li, Hailey M. Shepherd, Ramsey R. Hachem, Varun Puri, Kory J. Lavine, Andrew E. Gelman, Ankit Bharat, Daniel Kreisel, and Ruben G. Nava

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CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis, Steven J Grigsby, G V R Krishna Prasad, Joshua B Wallach, Ekansh Mittal, Fong-Fu Hsu, Dirk Schnappinger, and Jennifer A Philips

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Human whole-exome genotype data for Alzheimer's disease, Yuk Yee Leung, Carlos Cruchaga, and et al.

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Neural mechanisms of face familiarity and learning in the human amygdala and hippocampus, Runnan Cao, Jinge Wang, Peter Brunner, Jon T Willie, Xin Li, Ueli Rutishauser, Nicholas J Brandmeir, and Shuo Wang

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Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration, Michael K. Kanan, Patrick W. Sheehan, Jessica N. Haines, Pedro G. Gomez, Adya Dhuler, Collin J. Nadarajah, Zachary M. Wargel, Brittany M. Freeberg, Hemanth R. Nelvagal, Mariko Izumo, Joseph S. Takahashi, Jonathan D. Cooper, Albert A. Davis, and Erik S. Musiek

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Synergistic protection of retinal ganglion cells (RGCs) by SARM1 inactivation with CNTF in a rodent model of nonarteritic anterior ischemic optic neuropathy, Yan Guo, Zara Mehrabian, Jeffrey Milbrandt, Aaron DiAntonio, and Steven L Bernstein

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Targeting efferocytosis in inflammaging, Ivan K H Poon and Kodi S Ravichandran

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Self-renewing human naïve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously, Mingyue Guo, Jinyi Wu, Chuanxin Chen, Xinggu Wang, An Gong, Wei Guan, Rowan M Karvas, Kexin Wang, Mingwei Min, Yixuan Wang, Thorold W Theunissen, Shaorong Gao, and José C R Silva

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MyPathway human epidermal growth factor receptor 2 basket study: Pertuzumab + trastuzumab treatment of a tissue-agnostic cohort of patients with human epidermal growth factor receptor 2-altered advanced solid tumors, Christopher J Sweeney, Ron Bose, and et al.

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Comprehensive workflow and its validation for simulating diffuse speckle statistics for optical blood flow measurements, Lisa Kobayashi Frisk, Manish Verma, Faruk Bešlija, Chen-Hao P Lin, Nishighanda Patil, Sumana Chetia, Jason W Trobaugh, Joseph P Culver, and Turgut Durduran

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Drug preparation, injection-related infections, and harm reduction practices among a national sample of individuals entering treatment for opioid use disorder, Laura R Marks, Michael J Durkin, Kelly Ayres, and Matthew Ellis

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Factors affecting the ability of patients with complex vascular anomalies to navigate the healthcare system, Bryan Sisk, Sunny Lin, and Anna M Kerr

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Identification of molecular subphenotypes in two cohorts of paediatric ARDS, Nadir Yehya, Matt S Zinter, Jill M Thompson, Michelle J Lim, Mark R Hanudel, Mustafa F Alkhouli, Hector Wong, Matthew N Alder, Daniel J McKeone, E Scott Halstead, Pratik Sinha, and Anil Sapru

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Draft genomes of 12 Bifidobacterium isolates from human IBD fecal samples, Cole E Souza, Nicole E Jacobson, Michelle A An, Lindsay Droit, Alejandro A Vega, Mariel Rosales, Kathie A Mihindukulasuriya, Karina Pastrana, Scott A Handley, Miles Parkes, Joanna Rimmer, David Wang, Elizabeth A Dinsdale, Robert A Edwards, and Anca M Segall

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Post-exposure intranasal IFNα suppresses replication and neuroinvasion of Venezuelan Equine Encephalitis virus within olfactory sensory neurons, Matthew D Cain, N Rubin Klein, Xiaoping Jiang, Hamid Salimi, Qingping Wu, Mark J Miller, William B Klimstra, and Robyn S Klein

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Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function, Tae Jun Lee, Yo Sasaki, Philip A. Ruzycki, Norimitsu Ban, Joseph B. Lin, Hung-Ting Wu, Andrea Santeford, and Rajendra S. Apte

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Gut microbiome and antibiotic resistance effects during travelers' diarrhea treatment and prevention, Kevin S Blake, Drew J Schwartz, Srinand Paruthiyil, Bin Wang, Jie Ning, Harris Whiteson, Gautam Dantas, and et al.

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Hormonal basis of sex differences in anesthetic sensitivity, Andrzej Z Wasilczuk, Cole Rinehart, Adeeti Aggarwal, Martha E Stone, George A Mashour, Michael S Avidan, Max B Kelz, Alex Proekt, and ReCCognition Study Group

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Human pluripotent stem cell modeling of alveolar type 2 cell dysfunction caused by ABCA3 mutations, Yuliang L Sun, Erin E Hennessey, Hillary Heins, Ping Yang, Carlos Villacorta-Martin, Julian Kwan, Krithi Gopalan, Marianne James, Andrew Emili, F. Sessions Cole, Jennifer A. Wambach, and Darrell N. Kotton

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Ketosis prevents abdominal aortic aneurysm rupture through C-C chemokine receptor type 2 downregulation and enhanced extracellular matrix balance, Sergio Sastriques-Dunlop, Santiago Elizondo-Benedetto, Batool Arif, Rodrigo Meade, Mohamed S Zaghloul, Hannah Luehmann, Gyu S Heo, Sean J English, Yongjian Liu, and Mohamed A Zayed

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Progressive left ventricular remodeling for predicting mortality in children with dilated cardiomyopathy: The Pediatric Cardiomyopathy Registry, Paul F Kantor, Charles E Canter, and et al.

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Susceptibility of Toxoplasma gondii to autophagy in human cells relies on multiple interacting parasite loci, Nicholas Rinkenberger, Alex Rosenberg, Joshua B Radke, Jaya Bhushan, Tadakimi Tomita, Louis M Weiss, and L David Sibley

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Targeting cell-type-specific, choroid-peripheral immune signaling to treat age-related macular degeneration, Joseph B Lin, Andrea Santeford, Jason J Colasanti, Yoon Lee, Aaditya V Shah, Tzu Jui Wang, Philip A Ruzycki, and Rajendra S Apte

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Very-low-density lipoprotein triglyceride and free fatty acid plasma kinetics in women with high or low brown adipose tissue volume and overweight/obesity, Maria Chondronikola, Jun Yoshino, Raja Ramaswamy, Joseph Daniel Giardina, Richard Laforest, Richard L Wahl, Bruce W Patterson, Bettina Mittendorfer, and Samuel Klein

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Barriers and facilitators to a task-shifted stroke prevention program for children with sickle cell anemia in a community hospital: A qualitative study, Halima Bello-Manga, Lawal Haliru, Kudirat Ahmed, Samuel Ige, Hayatu Musa, Zainab Kwaru Muhammad-Idris, Binshak Monday, Abdulrashid M Sani, Kemberlee Bonnet, David G Schlundt, Taniya Varughese, Abdulkadir M Tabari, Michael R DeBaun, Ana A Baumann, and Allison A King

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Post-hospitalization remote monitoring for patients with heart failure or chronic obstructive pulmonary disease in an Accountable Care Organization, Samantha Harris, Kayla Paynter, Megan Guinn, Julie Fox, Nathan Moore, Thomas M Maddox, and Patrick G Lyons

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A flexible, quantitative plasmonic-fluor lateral flow assay for the rapid detection of Orthoebolavirus zairense and Orthoebolavirus sudanense, Abraham J Qavi, Qisheng Jiang, M Javad Aman, Hong Vu, Larry Zetlin, John M Dye, Jeffrey W Froude, Daisy W Leung, Frederick Holtsberg, Scott L Crick, and Gaya K Amarasinghe

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Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer, Vivian Truong Jones, Vishnu C Damalanka, James W Janetka, and et al.

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Overview of COVID-19 infection, treatment, and prevention in children, Carol M Kao

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Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state, Thomas F Barrett, Bhuvic Patel, Riley D Z Mullins, Aldrin K Y Yim, Sangami Pugazenthi, Tatenda Mahlokozera, Gregory J Zipfel, Jacques A Herzog, Cameron C Wick, Nedim Durakovic, Joshua W Osbun, Matthew Shew, Craig A Buchman, Sidharth V Puram, Albert H Kim, and et al.

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Neuroactive steroid effects on autophagy in a human embryonic kidney 293 (HEK) cell model, Sofia V Salvatore, Ma Xenia G Ilagan, Hongjin Shu, Peter M Lambert, Ann Benz, Mingxing Qian, Douglas F Covey, Charles F Zorumski, and Steven Mennerick

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Smaller total and subregional cerebellar volumes in posttraumatic stress disorder: A mega-analysis by the ENIGMA-PGC PTSD workgroup, Ashley A. Huggins, Evan M. Gordon, and et al.

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The chromatin landscape of healthy and injured cell types in the human kidney, Debora L Gisch, Jeannine Basta, Reetika Ghag, Charles Lu, Lisa Stout, Bo Zhang, Amanda Knoten, Shamim Mollah, Sanjay Jain, Michael Rauchman, and et al.

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Age-related differences in motor skill transfer with brief memory reactivation, Kylie B Tomlin, Brian P Johnson, and Kelly P Westlake

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Clinical outcomes of older and younger patients treated with loncastuximab tesirine in the LOTIS-2 clinical trial, Mehdi Hamadani, Brad Kahl, and et al.

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Implementing integrated hypertension and diabetes management using the World Health Organization's HEARTS model: Protocol for a pilot study in the Guatemalan national primary care system, Irmgardt Alicia Wellmann, Luis Fernando Ayala, José Javier Rodríguez, Timothy C Guetterman, Vilma Irazola, Eduardo Palacios, Mark D Huffman, Peter Rohloff, Michele Heisler, Manuel Ramírez-Zea, and David Flood

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Multiple pathways for glucose phosphate transport and utilization support growth of Cryptosporidium parvum, Rui Xu, Wandy L Beatty, Valentin Greigert, William H Witola, and L David Sibley

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Associations between coordination and wearable sensor variables vary by recording context but not assessment type, Jeffrey D Konrad, Natasha Marrus, Keith R Lohse, Kayla M Thuet, and Catherine E Lang

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Gene-SGAN: Discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering, Zhijian Yang, John C Morris, Pamela LaMontagne, Daniel S Marcus, Tammie L S Benzinger, and et al.

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Postnatal meningeal CSF transport is primarily mediated by the arachnoid and pia maters and is not altered after intraventricular hemorrhage-posthemorrhagic hydrocephalus, Shelei Pan, Joshua P Koleske, Gretchen M Koller, Grace L Halupnik, Abdul-Haq O Alli, Shriya Koneru, Dakota DeFreitas, Sruthi Ramagiri, and Jennifer M Strahle

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DGIdb 5.0: Rebuilding the Drug-Gene Interaction Database for precision medicine and drug discovery platforms, Matthew Cannon, James Stevenson, Kathryn Stahl, Rohit Basu, Adam Coffman, Susanna Kiwala, Joshua F McMichael, Kori Kuzma, Dorian Morrissey, Kelsy Cotto, Elaine R Mardis, Obi L Griffith, Malachi Griffith, and Alex H Wagner

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Phase I dose-escalation study of the safety and pharmacokinetics of AGS15E monotherapy in patients with metastatic urothelial carcinoma, Daniel P Petrylak, Joel Picus, and et al.

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Updates to the modern diagnosis of GERD: Lyon consensus 2.0, C Prakash Gyawali and et al.

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Effects of cooking with liquefied petroleum gas or biomass on stunting in infants, William Checkley, Lindsay J Underhill, Victor G Dávila-Román, and et al.

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Heterozygous mutations in the C-terminal domain of COPA underlie a complex autoinflammatory syndrome, Selket Delafontaine, Tarin M. Bigley, Megan A. Cooper, and et al.

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Inhibiting metabotropic glutamate receptor 5 after stroke restores brain function and connectivity, Jakob Hakon, Miriana J Quattromani, Carin Sjölund, Daniela Talhada, Byungchan Kim, Slavianka Moyanova, Federica Mastroiacovo, Luisa Di Menna, Roger Olsson, Elisabet Englund, Ferdinando Nicoletti, Karsten Ruscher, Adam Q Bauer, and Tadeusz Wieloch

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Liquefied petroleum gas or biomass cooking and severe infant pneumonia, Eric D. McCollum, Victor G. Davila-Roman, Lindsay J. Underhill, and et al.

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Low RNA disruption during neoadjuvant chemotherapy predicts pathologic complete response absence in patients with breast cancer, Marina Elena Cazzaniga, Foluso Ademuyiwa, and et al.

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Sarm1 knockout prevents type 1 diabetic bone disease in females independent of neuropathy, Jennifer M. Brazill, Ivana R. Shen, Clarissa S. Craft, Kristann L. Magee, Jay S. Park, Madelyn Lorenz, Amy Strickland, Natalie K. Wee, Xiao Zhang, Alec T. Beeve, Gretchen A. Meyer, Jeffrey Milbrandt, Aaron DiAntonio, and Erica L. Scheller

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Self-sampling tools to increase cancer screening among underserved patients: A pilot randomized controlled trial, Jennifer L Moss, Juliette Entenman, Kelsey Stoltzfus, Jiangang Liao, Tracy Onega, Paul L Reiter, Lisa M Klesges, George Garrow, and Mack T Ruffin

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Sensory neurons promote immune homeostasis in the lung, Masato Tamari, Aaron M Ver Heul, Masato Hoshi, Anna M Trier, Ting-Lin Yang, Sanjay Jain, Steven Van Dyken, and et al.

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The low-density lipoprotein receptor promotes infection of multiple encephalitic alphaviruses, Hongming Ma, Lucas J Adams, Saravanan Raju, Alan Sariol, Natasha M Kafai, Hana Janova, William B Klimstra, Daved H Fremont, and Michael S Diamond

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An applicable framework for understanding successful aging of people living with HIV and comorbid chronic obstructive pulmonary disease, Jun Y. Byun, Crystal Chapman Lambert, Pariya L. Fazeli, Burel R. Goodin, Anand S. Iyer, Mirjam-Colette Kempf, Jenni M. Wise, Yookyong Lee, David Scott Batey, and David E. Vance

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Implementation and outcomes of a pilot collaborative surgical hydrocele training in Côte d'Ivoire, Kevin Montes, Georgina Angoa, Catherine M Bjerum, Adama Guira, Olivier K Kouadio, Allassane F Ouattara, Gary J Weil, Peter U Fischer, Aboulaye Meite, Benjamin G Koudou, and Philip J Budge

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Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease, Lihua Wang, Niko-Petteri Nykänen, Daniel Western, Priyanka Gorijala, Jigyasha Timsina, Fuhai Li, Zhaohua Wang, Muhammad Ali, Chengran Yang, Menghan Liu, William Brock, Richard J Perrin, Yun Ju Sung, Carlos Cruchaga, and et al.

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Surveillance and selective treatment of Brugia malayi filariasis eleven years after stopping mass drug administration in Belitung District, Indonesia, Taniawati Supali, Yenny Djuardi, Santoso, Lita Renata Sianipar, Nungki Hapsari Suryaningtyas, Rahmat Alfian, Yossi Destani, Elisa Iskandar, Hendri Astuty, Noviani Sugianto, and Peter U Fischer

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A dataset of digital holograms of normal and thalassemic cells, Vahid Abbasian and Arash Darafsheh

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Breast cancer incidence among US women aged 20 to 49 years by race, stage, and hormone receptor status, Shuai Xu, Sara Murtagh, Yunan Han, Fei Wan, and Adetunji T Toriola

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Contrast response function estimation with nonparametric Bayesian active learning, Dom C P Marticorena, Quinn Wai Wong, Jake Browning, Ken Wilbur, Samyukta Jayakumar, Pinakin Gunvant Davey, Aaron R Seitz, Jacob R Gardner, and Dennis L Barbour

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Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use, Anna Worthmann, Sangeeta Adak, Clay F Semenkovich, and et al.

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Genome-wide and targeted CRISPR screens identify RNF213 as a mediator of interferon gamma-dependent pathogen restriction in human cells, Sumit K Matta, Hinissan P Kohio, Pallavi Chandra, Adam Brown, John G Doench, Jennifer A Philips, Siyuan Ding, and L David Sibley

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HAT: De novo variant calling for highly accurate short-read and long-read sequencing data, Jeffrey K Ng and Tychele N Turner

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Hecatomb: An integrated software platform for viral metagenomics, Michael J Roach, Sarah J Beecroft, Kathie A Mihindukulasuriya, Leran Wang, Anne Paredes, Luis Alberto Chica Cárdenas, Kara Henry-Cocks, Lais Farias Oliveira Lima, Elizabeth A Dinsdale, Robert A Edwards, and Scott A Handley

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Implications of preoperative depression for lumbar spine surgery outcomes: A systematic review and meta-analysis, Saad Javeed, Braeden Benedict, Salim Yakdan, Samia Saleem, Justin K Zhang, Kathleen Botterbush, Madelyn R Frumkin, Angela Hardi, Brian Neuman, Jay F Piccirillo, Burel R Goodin, Thomas L Rodebaugh, Wilson Z Ray, Jacob K Greenberg, and et al.

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Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel, Vikram Dalal, Mark J Arcario, John T Petroff 2nd, Brandon K Tan, Noah M Dietzen, Michael J Rau, James A J Fitzpatrick, Grace Brannigan, and Wayland W L Cheng

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Microbial co-occurrences on catheters from long-term catheterized patients, Taylor M Nye, Zongsen Zou, Chloe L P Obernuefemann, Jerome S Pinkner, Erin Lowry, Kent Kleinschmidt, Karla Bergeron, Aleksandra Klim, Karen W Dodson, Ana L Flores-Mireles, Jennifer N Walker, Daniel Garrett Wong, Alana Desai, Michael G Caparon, and Scott J Hultgren

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Organ preservation and survival by clinical response grade in patients with rectal cancer treated with total neoadjuvant therapy: A secondary analysis of the OPRA randomized clinical trial, Hannah M Thompson, Steven R Hunt, and et al.

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Process evaluation of a double-blind randomized controlled trial to assess the efficacy and safety of a Quadruple Ultra-Low-Dose Treatment for Hypertension within a federally qualified health center network (QUARTET USA), Olutobi A Sanuade, Tyler A Jacobson, Adriana Quintana, Fallon M Flowers, Hiba Abbasi, My H Vu, Abigail S Baldridge, Jairo Mejia, Danielle Lazar, Jody D Ciolino, Mark D Huffman, and Namratha R Kandula

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Short-stay units vs routine admission from the emergency department in patients with acute heart failure: The SSU-AHF randomized clinical trial, Peter S Pang, Douglas Char, and et al.

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Accuracy of TrUE-Net in comparison to established white matter hyperintensity segmentation methods: An independent validation study, Jeremy F Strain, Maryam Rahmani, Donna Dierker, Christopher Owen, Hussain Jafri, Andrei G Vlassenko, Kyle Womack, Jurgen Fripp, Duygu Tosun, Tammie L S Benzinger, Michael Weiner, Colin Masters, Jin-Moo Lee, John C Morris, Manu S Goyal, and ADOPIC and ADNI Investigators