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Submissions from 2022

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An open-label multi-center phase 1 safety study of BXQ-350 in children and young adults with relapsed solid tumors, including recurrent malignant brain tumors, Mohamed S Abdelbaki, Mariko Dawn DeWire Schottmiller, Timothy P Cripe, Richard C Curry, Charles A Cruze, Leah Her, Suzanne Demko, Denise Casey, and Bhuvana Setty

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A novel, likely pathogenic variant in UBTF-related neurodegeneration with brain atrophy is associated with a severe divergent neurodevelopmental phenotype, Rory J Tinker, Tiffany Guess, David C Rinker, Jonathan H Sheehan, Daniel Lubarsky, Binu Porath, Mackenzie Mosera, Ping Mayo, Emily Solem, Laura A Lee, Asha Sharam, and Jennifer Brault

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Approaches to healthcare personnel exemption requests from coronavirus disease 2019 (COVID-19) vaccination: Results of a national survey, Thomas R Talbot, Susan E Beekmann, Hilary M Babcock, and Philip M Polgreen

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A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model, Yurie Sato-Yamada, Amy Strickland, Yo Sasaki, Joseph Bloom, Aaron DiAntonio, and Jeffrey Milbrandt

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Association of leukocyte telomere length with perceived physical fatigability, Rain Katz, Emma L Gay, Allison L Kuipers, Joseph H Lee, Lawrence S Honig, Kaare Christensen, Mary F Feitosa, Mary K Wojczynski, Nancy W Glynn, and LLFS Research Group

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Axillary artery fibromuscular dysplasia in a symptomatic type B aortic dissection causing acute limb ischemia, Brian Sullivan, Nathan Droz, and Vipul Khetarpaul

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Basal bodies bend in response to ciliary forces, Anthony D Junker, Louis G Woodhams, Adam W J Soh, Eileen T O'Toole, Philip V Bayly, and Chad G Pearson

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Benefits of early treatment with natalizumab: A real-world study, Daniel Ontaneda, Ellen M Mowry, Scott D Newsome, Robert T Naismith, Jacqueline Nicholas, Elizabeth Fisher, Carl de Moor, Justin Bohn, Pei-Ran Ho, Al Sandrock, Richard Rudick, and James R Williams

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Bone metabolism and incretin hormones following glucose ingestion in young adults with pancreatic insufficient cystic fibrosis, Wang Shin Lei, Marissa J Kilberg, Babette S Zemel, Ronald C Rubenstein, Clea Harris, Saba Sheikh, Andrea Kelly, and Joseph M Kindler

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Changes in practice/outcomes of pediatric/congenital catheterization in response to the first wave of COVID, Brian Quinn, Andrew C Glatz, and et al.

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Changes in racial equity associated with participation in the Bundled Payments for Care Improvement Advanced Program, Gmerice Hammond, E John Orav, Jie Zheng, Arnold M Epstein, and Karen E Joynt Maddox

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Chronic cochlear implantation with and without electric stimulation in a mouse model induces robust cochlear influx of CX3CR1+/GFP macrophages, Alexander D Claussen, René Vielman Quevedo, Jonathon R Kirk, Timon Higgins, Brian Mostaert, Muhammad Taifur Rahman, Jacob Oleson, Reyna Hernandez, Keiko Hirose, and Marlan R Hansen

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Circulating tumour DNA characterisation of invasive lobular carcinoma in patients with metastatic breast cancer, Andrew A Davis, Katherine Clifton, Whitney L. Hensing, Nusayba A. Bagegni, Foluso O. Ademuyiwa, Ron Bose, Cynthia X. Ma, and et al.

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Cisplatin exposure acutely disrupts mitochondrial bioenergetics in the zebrafish lateral-line organ, David S Lee, Angela Schrader, Mark Warchol, and Lavinia Sheets

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Cognition and the single neuron: How cell types construct the dynamic computations of frontal cortex, Amelia J Christensen, Torben Ott, and Adam Kepecs

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Community access to primary care is an important geographic disparity among ovarian cancer patients undergoing cytoreductive surgery, Abigail S Zamorano, Angela L Mazul, Christine Marx, Mary M Mullen, Molly Greenwade, L Stewart Massad, Carolyn K McCourt, Andrea R Hagemann, Premal H Thaker, Katherine C Fuh, Matthew A Powell, David G Mutch, Dineo Khabele, and Lindsay M Kuroki

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Community prevalence of Helicobacter pylori and dyspepsia and efficacy of triple therapy in a rural district of eastern Uganda, Yang Jae Lee, Ibrahim Ssekalo, Rauben Kazungu, Timothy S Blackwell Jr, Peter Muwereza, Yuefeng Wu, and José B Sáenz

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Comparing antigenaemia- and microfilaraemia as criteria for stopping decisions in lymphatic filariasis elimination programmes in Africa, Wilma A. Stolk, Luc E. Coffeng, Fatorma K. Bolay, Obiora A. Eneanya, Peter U. Fischer, T. Déirdre Hollingsworth, Benjamin G. Koudou, Aboulaye Méité, Edwin Michael, Joaquin M. Prada, Rocio M. Caja Rivera, Swarnali Sharma, Panayiota Touloupou, Gary J. Weil, and Sake J. de Vlas

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Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc, Shirley N Tang, Andres F Bonilla, Nadeen O Chahine, Aimee C Colbath, Jeremiah T Easley, Sibylle Grad, Lisbet Haglund, Christine L Le Maitre, Victor Leung, Annette M McCoy, Devina Purmessur, Simon Y Tang, Stephan Zeiter, and Lachlan J Smith

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Cortical bone relationships are maintained regardless of sex and diet in a large population of LGXSM advanced intercross mice, Nicole Migotsky, Michael D Brodt, James M Cheverud, and Matthew J Silva

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Defining terms commonly used in sarcopenia research: A glossary proposed by the Global Leadership in Sarcopenia (GLIS) Steering Committee, Peggy M Cawthon, Ellen Binder, and et al.

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Delayed diagnosis and recovery of fulminant immune checkpoint inhibitor-associated myocarditis on VA-ECMO support, Tarun Ramayya, Joshua D Mitchell, Justin C Hartupee, Kory Lavine, Clare H Ridley, Kunal D Kotkar, Jesus Jimenez, Chieh-Yu Lin, Jose A Alvarez-Cardona, Ronald K Krone, and Courtney M Campbell

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Derivation and validation of a clinical prediction rule for upper limb functional outcomes after traumatic cervical spinal cord injury, Saad Javeed, Jacob K Greenberg, Justin K Zhang, Christopher F Dibble, Jawad M Khalifeh, Ying Liu, Thomas J Wilson, Lynda J Yang, Yikyung Park, and Wilson Z Ray

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Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer's trial selection and disease monitoring, Nicholas J Ashton, Yan Li, Randall J Bateman, and et al.

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Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment, Kristine Donahue, Haibo Xie, Miyang Li, Ang Gao, Min Ma, Yidan Wang, Rose Tipton, Nicole Semanik, Tina Primeau, Shunqiang Li, Lingjun Li, Weiping Tang, and Wei Xu

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First-generation and continuing-generation college graduates' application, acceptance, and matriculation to U.S. medical schools: A national cohort study, Hyacinth R C Mason, Ashar Ata, Mytien Nguyen, Sunny Nakae, Devasmita Chakraverty, Branden Eggan, Sarah Martinez, and Donna B Jeffe

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Glycemia and β-cell function before and after elexacaftor/tezacaftor/ivacaftor in youth and adults with cystic fibrosis, Christine L Chan, Andrea Granados, Amir Moheet, Sachinkumar Singh, Timothy Vigers, Ana Maria Arbeláez, Yaling Yi, Shanming Hu, Andrew W Norris, and Katie Larson Ode

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G protein gamma subunit, a hidden master regulator of GPCR signaling, Dinesh Kankanamge, Mithila Tennakoon, Ajith Karunarathne, and N Gautam

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Gunshot wound to the spine with delayed radiculopathy: A case report, Kunj Patel, Rachita Navara, Faizal Ouedraogo, Ronald Joel, and Brock Bowman

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Identification of patients with ovarian cancer experiencing the highest benefit from bevacizumab in the first-line setting on the basis of their tumor-intrinsic chemosensitivity (KELIM): The GOG-0218 validation study, Benoit You, David Mutch, and et al.

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Impact of aortic valve effective height following valve-sparing root replacement on postoperative insufficiency and reoperation, Puja Kachroo, Meghan O Kelly, Nadia H Bakir, Catherine Cooper, Alan C Braverman, Nicholas T Kouchoukos, and Marc R Moon

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Implementing educational and systems-level changes to improve cancer screening rates among state employees in Missouri, Misty A Phillips, Sarah Chavez, Maggie Grotefendt, Xarria Lewis, Melanie Gowdy, Jane A McElroy, Jean S Wang, and Sandra Hentges

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'I need time to start antiretroviral therapy': Understanding reasons for delayed ART initiation among people diagnosed with HIV in Lusaka, Zambia, Chanda Mwamba, Laura K Beres, Stephanie M Topp, Njekwa Mukamba, Sandra Simbeza, Kombatende Sikombe, Aaloke Mody, Elvin Geng, Charles B Holmes, Caitlin E Kennedy, Izukanji Sikazwe, Julie A Denison, and Carolyn Bolton Moore

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Infections in the first year of life and development of beta cell autoimmunity and clinical type 1 diabetes in high-risk individuals: The TRIGR cohort, Olga Kordonouri, David Cuthbertson, Malin Belteky, Bärbel Aschemeier-Fuchs, Neil H White, Elisabeth Cummings, Mikael Knip, and Johnny Ludvigsson

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Leflunomide-induced and paraneoplastic ulcers in a rheumatoid arthritis patient, Michael R Vittori, Jonathan Z Tang, and William H McCoy IV

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Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice, Randy Strong, Kerry Kornfeld, and et al.

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Listeria motility increases the efficiency of epithelial invasion during intestinal infection, Inge M. N. Wortel, Seonyoung Kim, Annie Y. Liu, Enid C. Ibarra, and Mark J. Miller

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Macrophage depletion blocks congenital SARM1-dependent neuropathy, Caitlin B Dingwall, Amy Strickland, Sabrina W Yum, Aldrin Ky Yim, Jian Zhu, Peter L. Wang, Yurie Yamada, Robert E. Schmidt, Yo Sasaki, A. Joseph Bloom, Aaron DiAntonio, and Jeffrey Milbrandt

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Mild hypoxic-ischemic encephalopathy (HIE): Timing and pattern of MRI brain injury, Yi Li, Jessica L Wisnowski, Lina Chalak, Amit M Mathur, Robert C McKinstry, Genesis Licona, Dennis E Mayock, Taeun Chang, Krisa P Van Meurs, Tai-Wei Wu, Kaashif A Ahmad, Marie-Coralie Cornet, Rakesh Rao, Aaron Scheffler, and Yvonne W Wu

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Mouse tissue harvest-induced hypoxia rapidly alters the in vivo metabolome, between-genotype metabolite level differences, and 13C-tracing enrichments, Adam J Rauckhorst, Nicholas Borcherding, Daniel J Pape, Alora S Kraus, Diego A Scerbo, and Eric B Taylor

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OpenSep: A generalizable open source pipeline for SOFA score calculation and Sepsis-3 classification, Mackenzie R Hofford, Sean C Yu, Alistair E W Johnson, Albert M Lai, Philip R O Payne, and Andrew P Michelson

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Outcomes in participants with failure of initial antibacterial therapy for hospital-acquired/ventilator-associated bacterial pneumonia prior to enrollment in the randomized, controlled phase 3 ASPECT-NP trial of ceftolozane/tazobactam versus meropenem, Marin H Kollef, Jean-François Timsit, Ignacio Martin-Loeches, Richard G Wunderink, Jennifer A Huntington, Erin H Jensen, Brian Yu, and Christopher J Bruno

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Pilot study: PARP1 imaging in advanced prostate cancer, Farrokh Dehdashti, Melissa A. Reimers, Kooresh I. Shoghi, Delphine L. Chen, Jingqin Luo, Buck Rogers, Russell K. Pachynski, Sreeja Sreekumar, Cody Weimholt, and Dong Zhou

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Practice patterns of induction therapy in severe anti-neutrophil cytoplasmic autoantibody-associated vasculitis, Faten Aqeel, Lillian Xu, Ojaswi Tomar, Jessica Duchen, Tingting Li, and Duvuru Geetha

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Primary open-angle glaucoma diagnosis from optic disc photographs using a Siamese network, Mingquan Lin, Lei Liu, Mae Gordon, Michael Kass, Fei Wang, Sarah H Van Tassel, and Yifan Peng

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Prolonged dexamethasone exposure enhances zebrafish lateral-line regeneration but disrupts mitochondrial homeostasis and hair cell function, Allison L Saettele, Hiu-Tung C Wong, Katie S Kindt, Mark E Warchol, and Lavinia Sheets

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Public interest in hyaluronic acid injections for knee osteoarthritis in the United States and Europe: An international Google Trends analysis, Samuel A Cohen, Robert H Brophy, Antonia F Chen, Karl C Roberts, Robert H Quinn, and Kevin G Shea

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Racial and ethnic differences in internal medicine residency assessments, Dowin Boatright, Nientara Anderson, Jung G Kim, Eric S Holmboe, William A McDade, Tonya Fancher, Cary P Gross, Sarwat Chaudhry, Mytien Nguyen, Max Jordan Nguemeni Tiako, Eve Colson, Yunshan Xu, Fangyong Li, James D Dziura, and Somnath Saha

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Racial and ethnic disparities in access to minimally invasive mitral valve surgery, Laurent G Glance, Karen E Joynt Maddox, Michael Mazzefi, Peter W Knight, Michael P Eaton, Changyong Feng, Miklos D Kertai, James Albernathy, Isaac Y Wu, Julie A Wyrobek, Marisa Cevasco, Nimesh Desai, and Andrew W Dick

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Risk of nonalcoholic fatty liver disease and associations with gastrointestinal cancers, Scott McHenry, Xiaoyu Zong, Mengyao Shi, Cassandra D L Fritz, Katrina S Pedersen, Linda R Peterson, Jeffrey K Lee, Ryan C Fields, Nicholas O Davidson, and Yin Cao

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Targeting the autophagy-lysosome pathway in a pathophysiologically relevant murine model of reversible heart failure, Sarah Evans, Xiucui Ma, Xiqiang Wang, Yana Chen, Chen Zhao, Carla J Weinheimer, Attila Kovacs, Brian Finck, Abhinav Diwan, and Douglas L Mann

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Ten simple rules and a template for creating workflows-as-applications, Michael J. Roach, N. Tessa Pierce-Ward, Radoslaw Suchecki, Vijini Mallawaarachchi, Bhavya Papudeshi, Scott A. Handley, C. Titus Brown, Nathan S. Watson-Haigh, and Robert A. Edwards

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The clinical landscape of cell-free DNA alterations in 1671 patients with advanced biliary tract cancer, J E Berchuck, B Tan, and et al.

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The clinical spectrum of SMA-PME and in vitro normalization of its cellular ceramide profile, Michelle M Lee, Toni S Pearson, and et al.

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The genetic risk factor CEL-HYB1 causes proteotoxicity and chronic pancreatitis in mice, Karianne Fjeld, Steven J Wilhelm, Jianguo Lin, Xunjun Xiao, Mark E Lowe, and et al.

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The multifaceted mechanisms of malignant glioblastoma progression and clinical implications, Rui Sun and Albert H Kim

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The zona incerta in control of novelty seeking and investigation across species, Ilya E Monosov, Takaya Ogasawara, Suzanne N Haber, J Alexander Heimel, and Mehran Ahmadlou

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Transferability of Alzheimer disease polygenic risk score across populations and its association with Alzheimer disease-related phenotypes, Sang-Hyuk Jung, Carlos Cruchaga, and et al.

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Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site, Vera J. E. van Vliet, Nitin Sharma, Safder S. Ganaie, Gaya K. Amarasinghe, and et al

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Vascular endothelial-cadherin as a marker of endothelial injury in preclinical Alzheimer disease, Rawan Tarawneh, Rachel S Kasper, Jessie Sanford, Chia-Ling Phuah, Jason Hassenstab, and Carlos Cruchaga

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Water T2 could predict functional decline in patients with dysferlinopathy, Ursula Moore, Alan Pestronk, and et al.

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Wellness and coping of physicians who worked in ICUs during the pandemic: A multicenter cross-sectional North American survey, Karen E. A. Burns, Rachel K. McDonald, and et al.

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Whole-genome and long-read sequencing identify a novel mechanism in RFC1 resulting in CANVAS syndrome, Katherine Abell King, Daniel J. Wegner, Robert C. Bucelli, Jessica Shapiro, Alexander J. Paul, Patricia I. Dickson, Jennifer A. Wambach, and Undiagnosed Disease Network

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X-linked hypophosphatemia caused by the prevailing North American PHEX variant c.*231A>G; exon 13–15 duplication is often misdiagnosed as ankylosing spondylitis and manifests in both men and women, Kathryn McCrystal Dahir, Margo Black, Gary S Gottesman, Erik A Imel, Steven Mumm, Cindy M Nichols, and Michael P Whyte

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HIV care experiences and health priorities during the first wave of COVID-19: Clients' perspectives - A qualitative study in Lusaka, Zambia, Njekwa Mukamba, Anjali Sharma, Chanda Mwamba, Herbert Nyirenda, Marksman Foloko, Kasapo Lumbo, Katerina Christopoulos, Sandra Simbeza, Kombatende Sikombe, Charles B Holmes, Elvin H Geng, Izukanji Sikazwe, Carolyn Bolton-Moore, and Laura K Beres

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Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: A joint analysis of OnCovid and ESMO-CoCARE registries, Alessio Cortellini, Gino M Dettorre, and et al.

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Clinical management of supratentorial non-skull case meningiomas, Adefisayo Adekanmbi, Mark W Youngblood, Constantine L Karras, Ephraim A Oyetunji, John Kalapurakal, Craig M Horbinski, Hinda Najem, Virginia B Hill, James P Chandler, Amy B Heimberger, Stephen T Magill, and Rimas V Lukas

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FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells, Matthew R Jones, Arun Lingampally, Negah Ahmadvand, Lei Chong, Jin Wu, Jochen Wilhem, Ana Ivonne Vazquez-Armendariz, Meshal Ansari, Susanne Herold, David M Ornitz, Herbert B Schiller, Cho-Ming Chao, Jin-San Zhang, Gianni Carraro, and Saverio Bellusci

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Gantenerumab: An anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer's disease, Randall J Bateman, Jeffrey Cummings, Scott Schobel, Stephen Salloway, Bruno Vellas, Mercè Boada, Sandra E Black, Kaj Blennow, Paulo Fontoura, Gregory Klein, Sheila Seleri Assunção, Janice Smith, and Rachelle S Doody

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Single-cell RNA sequencing identifies a paracrine interaction that may drive oncogenic notch signaling in human adenoid cystic carcinoma, Anuraag S. Parikh, Avishai Wizel, Daniel Davis, Armida Lefranc-Torres, Alejandro I. Rodarte-Rascon, Lauren E. Miller, Kevin S. Emerick, Mark A. Varvares, Daniel G. Deschler, William C. Faquin, Jon C. Aster, Derrick T. Lin, Bradley E. Bernstein, Yotam Drier, and Sidharth V. Puram

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Comprehensive transcriptomic analysis of VISTA in acute myeloid leukemia: Insights into its prognostic value, Simona Pagliuca, Carmelo Gurnari, Keman Zhang, Tariq Kewan, Waled Bahaj, Minako Mori, Ishani Nautiyal, Marie Thérèse Rubio, Francesca Ferraro, Jaroslaw P Maciejewski, Li Wang, and Valeria Visconte

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Non-standard viral genome-derived RNA activates TLR3 and type I IFN signaling to induce cDC1-dependent CD8+ T-cell responses during vaccination in mice, Devin G Fisher, Victoria Gnazzo, David J Holthausen, and Carolina B López

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Determining epigenetic memory in kidney proximal tubule cell derived induced pluripotent stem cells using a quadruple transgenic reprogrammable mouse, Gabriel Khelifi, Theresa Chow, Jennifer Whiteley, Victoire Fort, Benjamin D Humphreys, Samer M I Hussein, and Ian M Rogers

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Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples, Thomas Liechti, Yaser Iftikhar, Massimo Mangino, Margaret Beddall, Charles W Goss, Jane A O'Halloran, Philip A Mudd, and Mario Roederer

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CSF tau microtubule-binding region identifies pathological changes in primary tauopathies, Kanta Horie, Nicolas R Barthélemy, Yingxin He, Albert A Davis, Celeste M Karch, Richard J Perrin, Rama K Koppisetti, Faris Shaikh, Nupur Ghoshal, Randall J Bateman, Chihiro Sato, and et al.

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MaHPIC malaria systems biology data from Plasmodium cynomolgi sporozoite longitudinal infections in macaques, Jeremy D DeBarry, Xuntian Jiang, Daniel S Ory, and et al.

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Stakeholder engagement in eight comparative effectiveness trials in African Americans and Latinos with asthma, Tiffany Dy, Winifred J Hamilton, C Bradley Kramer, Andrea Apter, Jerry A Krishnan, James W Stout, Stephen J Teach, Alex Federman, John Elder, Tyra Bryant-Stephens, Rebecca J Bruhl, Shawni Jackson, and Kaharu Sumino

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Wakeful rest benefits recall, but not recognition, of incidentally encoded memory stimuli in younger and older adults, Peter R Millar and David A Balota

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Cortex-wide response mode of VIP-expressing inhibitory neurons by reward and punishment, Zoltán Szadai, Hyun-Jae Pi, Quentin Chevy, Katalin Ócsai, Dinu F Albeanu, Balázs Chiovini, Gergely Szalay, Gergely Katona, Adam Kepecs, and Balázs Rózsa

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Multilevel correlates of domain-specific physical activity among rural adults - A cross-sectional study, Alan M Beck, Natalicio H Serrano, Audrey Toler, and Ross C Brownson

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Muscle-specific ablation of glucose transporter 1 (GLUT1) does not impair basal or overload-stimulated skeletal muscle glucose uptake, Shawna L McMillin, Parker L Evans, William M Taylor, Luke A Weyrauch, Tyler J Sermersheim, Steven S Welc, Monique R Heitmeier, Richard C Hresko, Paul W Hruz, Francoise Koumanov, Geoffrey D Holman, E Dale Abel, and Carol A Witczak

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Chatbot-delivered cognitive behavioral therapy in adolescents with depression and anxiety during the COVID-19 pandemic: Feasibility and acceptability study, Ginger Nicol, Ruoyun Wang, Sharon Graham, Sherry Dodd, and Jane Garbutt

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Dose-dependent von Willebrand Factor inhibition by aptamer BB-031 correlates with thrombolysis in a microfluidic model of arterial occlusion, Susan M Shea, Kimberly A Thomas, Rassam M G Rassam, Emily P Mihalko, Christina Daniel, Bruce A Sullenger, Philip C Spinella, and Shahid M Nimjee

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Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish, Vishnu Muraleedharan Saraswathy, Lili Zhou, Anthony R McAdow, Brooke Burris, Deepika Dogra, Sven Reischauer, and Mayssa H Mokalled

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EEG-based grading of Immune Effector Cell-Associated Neurotoxicity Syndrome, Daniel K Jones, Fábio A Nascimento, and et al.

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Let's talk about antibiotics: A randomised trial of two interventions to reduce antibiotic misuse, Kathy Goggin, Emily A. Hurley, Brian R. Lee, Andrea Bradley-Ewing, Carey Bickford, Kimberly Pina, Evelyn Donis de Miranda, David Yu, Kirsten Weltmer, Sebastian Linnemayr, Christopher C. Butler, Jason G. Newland, and Angela L Myers

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Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts, Tobey J Betthauser, Dean F Wong, and et al.

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Return of non-ACMG recommended incidental genetic findings to pediatric patients: Considerations and opportunities from experiences in genomic sequencing, Kevin M Bowling, Michelle L Thompson, Melissa A Kelly, Sarah Scollon, Anne M Slavotinek, Bradford C Powell, Brian M Kirmse, Laura G Hendon, Kyle B Brothers, Bruce R Korf, Gregory M Cooper, John M Greally, and Anna C E Hurst

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Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB, Meghan H Murray, Aurore Cecile Valfort, Thomas Koelblen, Céline Ronin, Fabrice Ciesielski, Arindam Chatterjee, Giri Babu Veerakanellore, Bahaa Elgendy, John K Walker, Lamees Hegazy, and Thomas P Burris

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Transversus abdominis plane block with different bupivacaine concentrations in children undergoing unilateral inguinal hernia repair: A single-blind randomized clinical trial, Meltem Savran Karadeniz, Ayşe Gülşah Atasever, Emine Aysu Salviz, Emre Sertaç Bingül, Hayriye Şentürk Çiftçi, Müşerref Beril Dinçer, and Mukadder Orhan Sungur

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Effect of COVID-19 on the implementation of a multifaceted intervention to improve teamwork and quality for hospitalized patients: A qualitative interview study, Iva A Terwilliger, Milisa Manojlovich, Julie K Johnson, Mark V Williams, and Kevin J O'Leary

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An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma, Odai Darawshi, Barbara Muz, and et al.

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De novo serine biosynthesis from glucose predicts sex-specific response to antifolates in non-small cell lung cancer cell lines, Jasmin Sponagel, Siddhartha Devarakonda, Joshua B Rubin, Jingqin Luo, and Joseph E Ippolito

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Evaluation of cisplatin-induced pathology in the larval zebrafish lateral line, David S Lee, Angela Schrader, Emily Bell, Mark E Warchol, and Lavinia Sheets

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Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation, John T Petroff 2nd, Noah M Dietzen, Ezry Santiago-McRae, Brett Deng, Maya S Washington, Lawrence J Chen, K Trent Moreland, Zengqin Deng, Michael Rau, James A J Fitzpatrick, Peng Yuan, Thomas T Joseph, Jérôme Hénin, Grace Brannigan, and Wayland W L Cheng

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Collegiate wrestler with a bicuspid aortic valve and aortic dilation, Rahul Chhana, Christopher Rymer, Mahesh Vidula, Kristopher Fayock, Helene Glassberg, Chris Kusmiesz, Mustafa Husaini, Sanjay Sivalokanathan, Neel Chokshi, and Sheela Krishnan

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Economic evaluation of implementation science outcomes in low- and middle-income countries: A scoping review, Akash Malhotra, Abigail Barker, Victor G Davila-Roman, William Effah, and et al.

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SLc7a8 is a key amino acids supplier for the metabolic programs that sustain homeostasis and activation of type 2 innate lymphoid cells, Santosh K Panda, Do-Hyun Kim, Pritesh Desai, Patrick F Rodrigues, Raki Sudan, Susan Gilfillan, Marina Cella, Steven J Van Dyken, and Marco Colonna

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Relationship of neurite architecture to brain activity during task-based fMRI, Christin Schifani, Colin Hawco, Arash Nazeri, and Aristotle N Voineskos

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The quality of energy- and macronutrient-balanced diets regulates host susceptibility to influenza in mice, Taylor A Cootes, Nayan D Bhattacharyya, Susie S Y Huang, Lina Daniel, Kim S Bell-Anderson, Sebastian A Stifter, Tracy Chew, Samantha M Solon-Biet, Luis R Saraiva, Yi Cai, Xinchun Chen, Stephen J Simpson, and Carl G Feng