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Submissions from 2022

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β-amyloid PET harmonisation across longitudinal studies: Application to AIBL, ADNI and OASIS3, Pierrick Bourgeat, Manu Goyal, Pamela LaMontagne, John C Morris, and et al.

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Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance, Dhivya Sridaran, Surbhi Chouhan, Kiran Mahajan, Arun Renganathan, Cody Weimholt, Shambhavi Bhagwat, Melissa Reimers, Eric H Kim, Manish K Thakur, Muhammad A Saeed, Russell K Pachynski, Markus A Seeliger, W Todd Miller, Felix Y Feng, and Nupam P Mahajan

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Molecular subclasses of clear cell ovarian carcinoma and their impact on disease behavior and outcomes, Kelly L Bolton, Irenaeus C C Chan, Brian J Wiley, and et al.

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Race and gender-based perceptions of older septuagenarian adults, Forest Melton, Kelly Palmer, Sade Solola, Luis Luy, Kathryn Herrera-Theut, Leanne Zabala, Shannon M Knapp, Ryan Yee, Erika Yee, Elizabeth Calhoun, Megan C Thomas Hebdon, Natalie Pool, Nancy Sweitzer, and Khadijah Breathett

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Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia, Alaullah Sheikh, Brunda Tumala, Tim J Vickers, John C Martin, Bruce A Rosa, Subrata Sabui, Supratim Basu, Rita D Simoes, Makedonka Mitreva, Chad Storer, Erik Tyksen, Richard D Head, Wandy Beatty, Hamid M Said, and James M Fleckenstein

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Structural basis for mechanotransduction in a potassium-dependent mechanosensitive ion channel, Jonathan Mount, Grigory Maksaev, Brock T Summers, James A J Fitzpatrick, and Peng Yuan

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The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration, Sarah Opie-Martin, Jennifer Jockel-Balsarotti, Taha Bali, Wade Self, Timothy Miller, and et al.

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Collective genomic segments with differential pleiotropic patterns between cognitive dimensions and psychopathology, Max Lam, Chia-Yen Chen, W David Hill, Charley Xia, Ruoyu Tian, Daniel F Levey, Joel Gelernter, Murray B Stein, Alexander S Hatoum, Hailiang Huang, Anil K Malhotra, Heiko Runz, Tian Ge, and Todd Lencz

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Imprinted antibody responses against SARS-CoV-2 Omicron sublineages, Young-Jun Park, Zhuoming Liu, Javier Janer, Sean P J Whelan, Herbert W Virgin, and et al.

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Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment, Jasmin Sponagel, Jill K Jones, Cheryl Frankfater, Shanshan Zhang, Olivia Tung, Kevin Cho, Kelsey L Tinkum, Hannah Gass, Elena Nunez, Gary J Patti, Jingqin Luo, Joshua B Rubin, Joseph E Ippolito, and et al.

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Acute and postacute sequelae associated with SARS-CoV-2 reinfection, Benjamin Bowe, Yan Xie, and Ziyad Al-Aly

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Liquefied petroleum gas or biomass for cooking and effects on birth weight, Thomas F Clasen, Lindsay J Underhill, and et al.

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Persistence of onchocerciasis in villages in Enugu and Ogun states in Nigeria following many rounds of mass distribution of ivermectin, Uwem F Ekpo, Obiora A Eneanya, Edith N Nwankwo, Islamiat Y Soneye, Gary J Weil, Peter U Fischer, and Obioma C Nwaorgu

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An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening, Guohui Zhang, Xianjin Xu, Zhiguang Jia, Yanyan Geng, Hongwu Liang, Jingyi Shi, Martina Marras, Carlota Abella, Karl L Magleby, Jonathan R Silva, Jianhan Chen, Xiaoqin Zou, and Jianmin Cui

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FDG-PET/MRI for nonoperative management of rectal cancer: A prospective pilot study, Semra Ince, Malak Itani, Lauren E Henke, Radhika K Smith, Paul E Wise, Matthew G Mutch, Sean C Glasgow, Matthew L Silviera, Katrina S Pedersen, Steven R Hunt, Hyun Kim, and Tyler J Fraum

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A human STAT3 gain-of-function variant confers T cell dysregulation without predominant Treg dysfunction in mice, Erica G Schmitt, Kelsey A Toth, Samuel I Risma, Ana Kolicheski, Nermina Saucier, Rafael J. Feliciano Berríos, Zev J. Greenberg, Jennifer W. Leiding, Jack J. Bleesing, Akaluck Thatayatikom, Laura G. Schuettpelz, John R. Edwards, Tiphanie P. Vogel, and Megan A Cooper

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Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation, Patrick M Schaefer, Benjamin A Garcia, and et al.

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Genetic addiction risk severity assessment identifies polymorphic reward genes as antecedents to reward deficiency syndrome (RDS) hypodopaminergia's effect on addictive and non-addictive behaviors in a nuclear family, Catherine A Dennen, Kenneth Blum, Abdalla Bowirrat, Panayotis K Thanos, Igor Elman, Mauro Ceccanti, Rajendra D Badgaiyan, Thomas McLaughlin, Ashim Gupta, Anish Bajaj, David Baron, B William Downs, Debasis Bagchi, and Mark S Gold

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Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription, Vincent Peng, Siyan Cao, Tihana Trsan, Jennifer K Bando, Julian Avila-Pacheco, John L Cleveland, Clary Clish, Ramnik J Xavier, and Marco Colonna

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The evolution, current indications and outcomes of cementless total knee arthroplasty, Maria T Schwabe and Charles P Hannon

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Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity, Madison S Strine, Mia Madel Alfajaro, Vincent R Graziano, Jaewon Song, Leon L Hsieh, Ryan Hill, Jun Guo, Kelli L VanDussen, Robert C Orchard, Megan T Baldridge, Sanghyun Lee, and Craig B Wilen

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High-throughput analysis of tissue microarrays using automated desorption electrospray ionization mass spectrometry, Nicolás M Morato, Hannah Marie Brown, Diogo Garcia, Erik H Middlebrooks, Mark Jentoft, Kaisorn Chaichana, Alfredo Quiñones-Hinojosa, and R Graham Cooks

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Socioeconomic status and modification of atherosclerotic cardiovascular disease risk prediction: Epidemiological analysis using data from the Atherosclerosis Risk In Communities study, Kamal Henderson, Brystana Kaufman, Jason S. Rotter, Sally Stearns, Carla A A Sueta, Randi Foraker, P Michael Ho, and Patricia P Chang

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Oxidative stress-induced cellular senescence in aging retina and age-related macular degeneration, Ryo Terao, Tazbir Ahmed, Ayana Suzumura, and Hiroko Terasaki

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Preventive behaviors and information sources during COVID-19 pandemic: A cross-sectional study in Japan, Manae Uchibori, Cyrus Ghaznavi, Michio Murakami, Akifumi Eguchi, Hiroyuki Kunishima, Satoshi Kaneko, Keiko Maruyama-Sakurai, Hiroaki Miyata, and Shuhei Nomura

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Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy, Lai Man Natalie Wu, Joshua Rubin, and et al.

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Bi-allelic CAMSAP1 variants cause a clinically recognizable neuronal migration disorder, Reham Khalaf-Nazzal, Jennifer L Griffith, Joseph R Walsh, Amber Neilson, Evguenia Kouranova, Xiaoxia Cui, David T Curiel, and et al.

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Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes, Chia-Jung Lee, Ting-Huei Chen, Aylwin Ming Wee Lim, Chien-Ching Chang, Jia-Jyun Sie, Pei-Lung Chen, Su-Wei Chang, Shang-Jung Wu, Chia-Lin Hsu, Ai-Ru Hsieh, Wei-Shiung Yang, and Cathy S J Fann

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Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter, Michael Lim, George Ansstas, and et al.

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Proteogenomic markers of chemotherapy resistance and response in triple-negative breast cancer, Meenakshi Anurag, Shunqiang Li, Ian S Hagemann, Jeremy Hoog, Foluso O Ademuyiwa, and et al.

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The 5-hydroxymethylcytosine landscape of prostate cancer, Martin Sjöström, Nupam P Mahajan, Christopher A Maher, and et al.

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The 5-hydroxymethylcytosine landscape of prostate cancer, Martin Sjöström, Nupam P Mahajan, Christopher A Maher, and et al.

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Accounting for the growth of observation stays in the assessment of Medicare's Hospital Readmissions Reduction Program, Amber K Sabbatini, Karen E Joynt-Maddox, Joshua M Liao, Anirban Basu, Canada Parrish, William Kreuter, and Brad Wright

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A comparison of methods to harmonize cortical thickness measurements across scanners and sites, Delin Sun, Evan Gordon, and et al.

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Acute-onset, painful, acral granuloma annulare in a 52-year-old female, Faisal S Ahmad, Michael R Vittori, and William H McCoy IV

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Age-dependent rebound in asthma exacerbations after COVID-19 lockdown, Guy Hazan, Carolyn Fox, Huram Mok, and Jeffrey Haspel

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American Cochlear Implant Alliance Task Force guidelines for clinical assessment and management of adult cochlear implantation for single-sided deafness, Margaret T. Dillon, Armine Kocharyan, Ghazal S. Daher, Matthew L. Carlson, William H. Shapiro, Hillary A. Snapp, and Jill B. Firszt

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Amyloid-β and tau deposition influences cognitive and functional decline in Down syndrome, Monika Grigorova, Beau Ances, and et al.

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An assessment of pediatric residency applicant perceptions of "Fit" during the virtual interview era, Jason D. Vadhan, Jorge G. Zarate Rodriguez, Michael Wallendorf, Michael M. Awad, and Andrew J. White

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A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication, Ghjuvan'Ghjacumu Shackleford, Yo Sasaki, and et al.

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A phase I first-in-human study of ABBV-383, a B-cell maturation antigen × CD3 bispecific T-cell redirecting antibody, in patients with relapsed/refractory multiple myeloma, Anita D'Souza, Ravi Vij, and et al.

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A preclinical and phase Ib study of palbociclib plus nab-paclitaxel in patients with metastatic adenocarcinoma of the pancreas, Manuel Hidalgo, Kian-Huat Lim, and et al.

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A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond, Marcus S Noel, Semmie Kim, Marion L Hartley, Steve Wong, Vincent J Picozzi, Harry Staszewski, Dae Won Kim, Jan M Van Tornout, Philip Agop Philip, Vincent Chung, Allyson J Ocean, and Andrea Wang-Gillam

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A report of 2 cases of the use of the Inari FlowTriever System in the treatment of pulmonary embolism, Richard Pham, Alexander Sasha Ushinsky, Naganathan Mani, and Pavan K Kavali

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Ascertainment of vaccination status by self-report versus source documentation: Impact on measuring COVID-19 vaccine effectiveness, Meagan Stephenson, Jennie H Kwon, and et al

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Assessment of infectious diseases risks from dental aerosols in real-world settings, Shruti Choudhary, Tracey Bach, Meghan A Wallace, Daniel C Stoeckel, Martin H Thornhill, Peter B Lockhart, Jennie H Kwon, Stephen Y Liang, Carey-Ann D Burnham, Pratim Biswas, Heidi M Steinkamp, and Michael J Durkin

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Association of noncontrast computed tomography and perfusion modalities with outcomes in patients undergoing late-window stroke thrombectomy, Guilherme B F Porto, Joshua Osbun, and et al.

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Associations between transcranial Doppler vasospasm and clinical outcomes after aneurysmal subarachnoid hemorrhage: A retrospective observational study, Abhijit V. Lele, Rafael Wabl, Sarah Wahlster, Jade Keen, Andrew M. Walters, Christine T. Fong, Vasu B. Dhulipala, Umeshkumar Athiraman, Anne Moore, Monica S. Vavilala, Louis J. Kim, and Michael R. Levitt

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Better operating room ventilation as determined by a novel ventilation index is associated with lower rates of surgical site infections, Bernard Surial, Andrew Atkinson, Rüdiger Külpmann, Arnold Brunner, Kurt Hildebrand, Benoît Sicre, Nicolas Troillet, Andreas Widmer, Eveline Rolli, Judith Maag, and Jonas Marschall

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Brain volume in chronic ketamine users - Relationship to sub-threshold psychotic symptoms and relevance to schizophrenia, Robert A Chesters, Fiona Pepper, Celia Morgan, Jonathan D Cooper, Oliver D Howes, Anthony C Vernon, and James M Stone

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Brain-wide versus genome-wide vulnerability biomarkers for severe mental illnesses, Peter Kochunov, Aris Sotiras, and et al.

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Clinical characteristics of children with cerebral injury preceding treatment of diabetic ketoacidosis, Nicole S Glaser, Kimberly S Quayle, and et al.

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Comparison of indirect fungal diagnostic tests in patients with proven histoplasmosis, Gayathri Krishnan, Margaret Power, J Ryan Bariola, and Ryan Dare

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Comparison of plasma and CSF biomarkers in predicting cognitive decline, Andrew J Aschenbrenner, Yan Li, Rachel L Henson, Katherine Volluz, Jason Hassenstab, Philip Verghese, Tim West, Matthew R Meyer, Kristopher M Kirmess, Anne M Fagan, Chengjie Xiong, David Holtzman, John C Morris, Randall J Bateman, and Suzanne E Schindler

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Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease, Jeremy F. Strain, Matthew R. Brier, Aaron Tanenbaum, Brian A. Gordon, John E. McCarthy, Aylin Dincer, Daniel S. Marcus, Richard J. Perrin, John C. Morris, Tammie L. S. Benzinger, Randall J. Bateman, Beau M. Ances, Abraham Z. Snyder, and et al.

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Dose-dependent seizure control with MEK inhibitor therapy for progressive glioma in a child with neurofibromatosis type 1, Evan Cantor, Ashley Meyer, Stephanie M Morris, Judith L Z Weisenberg, and Nicole M Brossier

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Durable melanoma control following disseminated talimogene laherparepvec herpetic infection, Leonid Shmuylovich, Aubriana M McEvoy, Ryan C Fields, Leonel Hernandez-Aya, George Ansstas, and David Y Chen

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Engineering diverse fatty acid compositions of phospholipids in Escherichia coli, Wenqin Bai, Winston E Anthony, Christopher J Hartline, Shaojie Wang, Bin Wang, Jie Ning, Fong-Fu Hsu, Gautam Dantas, and Fuzhong Zhang

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Facial paresis as the first sign in atypical facioscapulohumeral muscular dystrophy, Nneoma S. Wamkpah and John J. Chi

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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers, Iris E Jansen, Muhammad Ali, Yun Ju Sung, Carlos Cruchaga, Duber Gomez-Fonseca, and et al.

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Guidance for the diagnosis and treatment of hypolipidemia disorders, Cindy Bredefeld, Nicholas O Davidson, and et al.

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Herpes simplex virus and rates of cognitive decline or whole brain atrophy in the Dominantly Inherited Alzheimer Network, Charlotte Warren-Gash, Brian A Gordon, Eric McDade, Randall J Bateman, John C Morris, and et al.

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Hospital trajectories and early predictors of clinical outcomes differ between SARS-CoV-2 and influenza pneumonia, Patrick G Lyons, Aaloke Mody, Alice Bewley, Katherine Dittman, Aisling Doyle, Samuel L Windham, Tej M Patel, Bharat Neelam Raju, Matthew Keller, Andrew P Michelson, Thomas Kannampallil, Elvin H Geng, Pratik Sinha, and et al.

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Human immunodeficiency virus pre-exposure prophylaxis knowledge, attitudes, and self-efficacy among family planning providers in the Southern United States: Bridging the gap in provider training, Aditi Ramakrishnan, Jessica M Sales, Micah McCumber, Leah Powell, and Anandi N Sheth

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Implementation of an electronic, secure, web-based application to support routine hand hygiene observation with immediate direct feedback and anonymized benchmarking, Simon Simonet, Jonas Marschall, Rolf Kuhn, Matthias Schlegel, and Christian R Kahlert

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Implementation of telemedicine infectious diseases consultation in a rural hospital using the Active Implementation Framework, Jason P Burnham, Stephanie A Fritz, and Graham A Colditz

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Infectious complications of abortion, L. Lewis Wall and Awol Yemane

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Inositol phosphorylceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates, F Matthew Kuhlmann, Phillip N Key, Suzanne M Hickerson, John Turk, Fong-Fu Hsu, and Stephen M Beverley

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International consensus guidelines for adjuvant radiation therapy for bladder cancer after radical cystectomy: Update from an IBIS workgroup, Flor Verghote, Paul Sargos, John P Christodouleas, Vedang Murthy, Brian C Baumann, Piet Dirix, Charlien Berghen, Leen Paelinck, Tom Vercauteren, and Valérie Fonteyne

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Local failure events in prostate cancer treated with radiotherapy: A pooled analysis of 18 randomized trials from the Meta-analysis of Randomized Trials in Cancer of the Prostate Consortium (LEVIATHAN), Ting Martin Ma, Jeff M Michalski, and et al.

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Loneliness, social isolation, and social support in older adults with active cancer during the COVID-19 pandemic, Katherine Clifton, Feng Gao, JoAnn Jabbari, Mary Van Aman, Patricia Dulle, Janice Hanson, and Tanya M Wildes

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Manufacturing-dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development, Neeltje Steeghs, Haeseong Park, and et al.

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N-terminal acetylation and arginylation of actin determines the architecture and assembly rate of linear and branched actin networks, Samantha M Chin, Tomoyuki Hatano, Lavanya Sivashanmugam, Andrejus Suchenko, Anna S Kashina, Mohan K Balasubramanian, and Silvia Jansen

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Pembrolizumab for patients with non-Hodgkin lymphoma: Phase 1b KEYNOTE-013 study, John Kuruvilla, Nancy L Bartlett, and et al.

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Peroxisomal regulation of energy homeostasis: Effect on obesity and related metabolic disorders, Brian Kleiboeker and Irfan J Lodhi

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Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1L, Cuige Zhu, Mari Iwase, Ziqian Li, Faliang Wang, Annabel Quinet, Alessandro Vindigni, and Jieya Shao

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Quantification of sulcal emergence timing and its variability in early fetal life: Hemispheric asymmetry and sex difference, Hyuk JIn Yun, Hyun Ju Lee, Joo Young Lee, Tomo Tarui, Caitlin K. Rollins, Cynthia M. Ortinau, Henry A. Feldman, P. Ellen Grant, and Kiho Im

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Quantitative tumor depth determination using dual wavelength excitation fluorescence, Christine M. O'Brien, Kevin W. Bishop, Haini Zhang, Xiao Xu, Leo Shmuylovich, Elizabeth Conley, Karen Nwosu, Kathleen Duncan, Suman B. Mondal, and Gail Sudlow

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Real-world evidence supporting Tandem Control-IQ hybrid closed-loop success in the Medicare and Medicaid type 1 and type 2 diabetes populations, Gregory P Forlenza, Anders L Carlson, Rodolfo J Galindo, Davida F Kruger, Carol J Levy, Janet B McGill, Guillermo Umpierrez, and Grazia Aleppo

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Real-world utilization and outcomes of systemic therapy among patients with advanced or recurrent endometrial cancer in the United States, Jinan Liu, Bruno Emond, Eric M Maiese, Marie-Hélène Lafeuille, Patrick Lefebvre, Isabelle Ghelerter, Caterina Wu, Jean A Hurteau, and Premal H Thaker

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Risk-adjusted safety analysis of the oral JAK2/IRAK1 inhibitor pacritinib in patients with myelofibrosis, Naveen Pemmaraju, Claire Harrison, Vikas Gupta, Srdan Verstovsek, Bart Scott, Stephen T Oh, Francesca Palandri, Haifa Kathrin Al-Ali, Marta Sobas, Mary Frances McMullin, Ruben Mesa, Sarah Buckley, Karisse Roman-Torres, Alessandro Vannucchi, and Abdulraheem Yacoub

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Self-care management of bothersome symptoms as recommended by clinicians for patients with a chronic condition: A Delphi study, Heleen Westland, Shayleigh Dickson Page, Michelle van Rijn, Subhash Aryal, Kenneth E Freedland, Christopher Lee, Anna Strömberg, Ercole Vellone, Douglas J Wiebe, Tiny Jaarsma, and Barbara Riegel

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The programmed death-1 signaling axis modulates inflammation and LV structure/function in a stress-induced cardiomyopathy model, Tomohiro Hayashi, Sajal K Tiwary, Kory J Lavine, Sandeep Acharya, Michael Brent, Luigi Adamo, Attila Kovacs, and Douglas L Mann

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The serotonin receptor 3E variant is a risk factor for female IBS-D, Nikola Fritz, Gregory Sayuk, and et al.

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To calibrate or not to calibrate? A methodological dilemma in experimental pain research, Waclaw M Adamczyk, Tibor M Szikszay, Hadas Nahman-Averbuch, Jacek Skalski, Jakub Nastaj, Philip Gouverneur, and Kerstin Luedtke

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Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo, Kelli D Fenelon, Evan Thomas, Mohammad Samani, Min Zhu, Hirotaka Tao, Yu Sun, Helen McNeill, and Sevan Hopyan

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TRIM-NHL protein, NHL-2, modulates cell fate choices in the C. elegans germ line, John L. Brenner, Erin M. Jyo, Ariz Mohammad, Paul Fox, Vovanti Jones, Elaine Mardis, Tim Schedl, and Eleanor M. Maine

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Upper limb nerve transfer surgery in patients with tetraplegia, Saad Javeed, Christopher F Dibble, Jacob K Greenberg, Justin K Zhang, Jawad M Khalifeh, Yikyung Park, Thomas J Wilson, Eric L Zager, Amir H Faraji, Mark A Mahan, Lynda J Yang, Rajiv Midha, Neringa Juknis, and Wilson Z Ray

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Diagnosis and management of functional tic-like phenomena, Irene A Malaty, Seonaid Anderson, Shannon M Bennett, Cathy L Budman, Barbara J Coffey, Keith A Coffman, Erica Greenberg, Joseph F McGuire, Kirsten R Müller-Vahl, Michael S Okun, Julio Quezada, Amy Robichaux-Viehoever, and Kevin J Black

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High-speed, scanned laser structuring of multi-layered eco/bioresorbable materials for advanced electronic systems, Quansan Yang, Yameng Xu, Ying Yan, Wilson Z Ray, Mitchell A Pet, Matthew R MacEwan, and et al.

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Identification of novel genes and proteoforms in Angiostrongylus costaricensis through a proteogenomic approach, Esdras Matheus Gomes da Silva, Karina Mastropasqua Rebello, Young-Jun Choi, Vitor Gregorio, Alexandre Rossi Paschoal, Makedonka Mitreva, James H McKerrow, Ana Gisele da Costa Neves-Ferreira, and Fabio Passetti

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Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis, Yoshiharu Muto, Eryn E Dixon, Yasuhiro Yoshimura, Haojia Wu, Kohei Omachi, Nicolas Ledru, Parker C Wilson, Jeffrey H Miner, Benjamin D Humphreys, and et al.

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Myocardial infarction size as an independent predictor of intramyocardial haemorrhage in acute reperfused myocardial ischaemic rats, Rui Xia, Tong Zhu, Yu Zhang, Bo He, Yushu Chen, Lei Wang, Yang Zhou, Jichun Liao, Jie Zheng, Yongmei Li, Fajin Lv, and Fabao Gao

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Discovery and characterization of potent, efficacious, orally available antimalarial Plasmepsin X inhibitors and preclinical safety assessment of UCB7362, Martin A Lowe, Daniel E Goldberg, and et al.

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Genetic addiction risk and psychological profiling analyses for "preaddiction" severity index, Kenneth Blum, Mark S Gold, and et al.

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Mindfulness training for depressed older adults using smartphone technology: Protocol for a fully remote precision clinical trial, Abigail Schweiger, Thomas L Rodebaugh, Eric J Lenze, Katie Keenoy, Jason Hassenstab, Jeanne Kloeckner, Torie R Gettinger, and Ginger E Nicol

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Risk factors and treatment strategy for retinal vascular occlusive diseases, Ryo Terao, Ryosuke Fujino, and Tazbir Ahmed

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Strategies for de-implementation of low-value care-A scoping review, Sara Ingvarsson, Henna Hasson, Ulrica von Thiele Schwarz, Per Nilsen, Byron J Powell, Clara Lindberg, and Hanna Augustsson

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Comparison of metagenomic sequencing and the NanoString nCounter analysis system for the characterization of bacterial and viral communities in vaginal samples, Todd N Wylie, Jane Schrimpf, Haley Gula, Brandi N Herter, and Kristine M Wylie

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Emergence of compensatory mutations reveals the importance of electrostatic interactions between HIV-1 integrase and genomic RNA, Christian Shema Mugisha, Tung Dinh, Abhishek Kumar, Kasyap Tenneti, Jenna E Eschbach, Keanu Davis, Robert Gifford, Mamuka Kvaratskhelia, and Sebla B Kutluay