Open access journal articles published by WashU Medicine faculty in 2020 to the current year.
Submissions from 2024
The burden of cardiovascular disease attributable to hypertension in Nigeria: A modelling study using summary-level data, Adedayo E Ojo, Dike B Ojji, Diederick E Grobbee, Mark D Huffman, and Sanne A E Peters
Evaluation of copanlisib in combination with eribulin in triple-negative breast cancer patient-derived xenograft models, Zhanfang Guo, Jingqin Luo, R Jay Mashl, Jeremy Hoog, Piyush Maiti, Nikki Fettig, Sherri R Davies, Rebecca Aft, Jason M Held, Ramaswamy Govindan, Li Ding, Shunqiang Li, Cornelius von Morze, Kooresh I Shoghi, Cynthia X Ma, and et al.
Frontline assessors' opinions about grading committees in a medicine clerkship, Sophia K Lewis, Nathanial S Nolan, and Lisa Zickuhr
Giant left ventricular aneurysm with dynamic right ventricular compression and subsequent end-stage heart failure, Colin A Martz, Jonathan D Moreno, Justin M Vader, Joel D Schilling, and Amit Pawale
TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice, Mario Ruiz Pérez, Kodi Ravichandran, and et al.
COMPANION-002 a clinical trial of investigational drug CTX-009 plus paclitaxel vs paclitaxel in second line advanced BTC, Nilofer Azad, Olivia Aranha, and et al.
Debriefer cognitive load during Traditional Reflective Debriefing vs. Rapid Cycle Deliberate Practice interdisciplinary team training, Susan Wiltrakis, Ruth Hwu, Sherita Holmes, Srikant Iyer, Nandranie Goodwin, Claire Mathai, Scott Gillespie, Kiran B Hebbar, and Nora Colman
Cannabis, tobacco use, and COVID-19 outcomes, Nicholas B Griffith, Timothy B Baker, Brendan T Heiden, Nina Smock, Giang Pham, Jingling Chen, Justin Yu, James Reddy, Albert M Lai, Eric Hogue, Laura J Bierut, and Li-Shiun Chen
Generalized genetic liability to substance use disorders, Alex P. Miller, Ryan Bogdan, Arpana Agrawal, and Alexander S. Hatoum
Glutamatergic supramammillary nucleus neurons respond to threatening stressors and promote active coping, Abraham Escobedo, Salli-Ann Holloway, Megan Votoupal, Aaron L Cone, Hannah Skelton, Alex A Legaria, Imeh Ndiokho, Tasheia Floyd, Alexxai V Kravitz, Michael R Bruchas, and Aaron J Norris
Hexamerization: Explaining the original sin of IgG-mediated complement activation in acute lung injury, Hrishikesh S. Kulkarni
Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure, Sudipta Das, Janet S Lee, and et al.
Phantasus, a web application for visual and interactive gene expression analysis, Maksim Kleverov, Daria Zenkova, Vladislav Kamenev, Margarita Sablina, Maxim N Artyomov, and Alexey A Sergushichev
Secure messaging and telephone use for clinician-to-clinician communication, Sunny S Lou, Daphne Lew, Laura R Baratta, Elise Eiden, Christine A Sinsky, and Thomas Kannampallil
Severe pediatric neurological manifestations with SARS-CoV-2 or MIS-C hospitalization and new morbidity, Conall Francoeur, Kristin P Guilliams, Shannon C Agner, and et al.
aEEG in the first 3 days after extremely preterm delivery relates to neurodevelopmental outcomes, Roberta Pineda, Zachary Vesoulis, Nathalie El Ters, and Amit Mathur
A microbiota-directed complementary food intervention in 12-18-month-old Bangladeshi children improves linear growth, Ishita Mostafa, Matthew C Hibberd, Steven J Hartman, Md Hasan Hafizur Rahman, Mustafa Mahfuz, S M Tafsir Hasan, Per Ashorn, Michael J Barratt, Tahmeed Ahmed, and Jeffrey I Gordon
An evaluation of the outcomes associated with peritoneal catheter use in neonates undergoing cardiac surgery: A multicenter study, David M Kwiatkowski, Tara M Neumayr, and et al.
Anomalous left superior vena cava predisposing to recurrent brain abscesses: A case report and review of the literature, Adnan Shaik, Karan Joseph, Rahim Abo Kasem, Angela Downes, and Muhammed B. Janjua
ASCC1 structures and bioinformatics reveal a novel Helix-Clasp-Helix RNA-binding motif linked to a two-histidine phosphodiesterase, Naga Babu Chinnam, Jennifer M Soll, Nima Mosammaparast, and et al.
BCAR4 expression as a predictive biomarker for endocrine therapy resistance in breast cancer, Muheng Liao, Jace Webster, Emily M Coonrod, Katherine N Weilbaecher, Christopher A Maher, and Nicole M White
Changes in online marketing and sales practices among non-medical cannabis retailers in 5 US cities, 2022 to 2023, Yuxian Cui, Zongshuan Duan, Cassidy R LoParco, Katie Vinson, Katelyn F Romm, Yan Wang, Patricia A Cavazos-Rehg, Erin Kasson, Y Tony Yang, and Carla J Berg
Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice, Irina L Tourkova, Quitterie C Larrouture, Silvia Liu, Jianhua Luo, Katherine E Shipman, Kelechi M Onwuka, Ora A Weisz, Vladimir Riazanski, Deborah J Nelson, Matthew L MacDonald, Paul H Schlesinger, and Harry C Blair
Co-aggregation with apolipoprotein E modulates the function of amyloid-β in Alzheimer's disease, Zengjie Xia, Michael R Strickland, Hong Jiang, David M Holtzman, and et al.
Efficacy and safety of a four-drug, quarter-dose treatment for hypertension: The QUARTET USA randomized trial, Mark D Huffman and et al.
Ethological computational psychiatry: Challenges and opportunities, Ilya E Monosov, Jan Zimmermann, Michael J Frank, Mackenzie W Mathis, and Justin T Baker
Faculty onboarding for workforce readiness and belonging, Melissa M. Masaracchia, Scott D. Markowitz, Norah R. Janosy, and Kim M. Strupp
Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans, Alexandra Schäfer, Laura A VanBlargan, Larissa B Thackray, Michael S Diamond, and et al.
Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer, R S Laskar, Y Cao, and et al.
Haptic curing with endolaser after lens tilt in the Yamane technique, James C Liu and Arsham Sheybani
Implementation and prospective performance evaluation of an intraoperative duration prediction model using high throughput real-time data, York Jiao and Thomas Kannampallil
Infectious diseases physician management of cryptococcal meningitis in North America-Is single high-dose liposomal amphotericin B being used?, Nathan C Bahr, Susan E Beekmann, Philip M Polgreen, Jeremey B Walker, Andrej Spec, David R Boulware, and John W Baddley
Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans, Samuel D Chauvin, Fang R Zhao, W Alexander Stinson, Wei Qian, Prabhakar S Andhey, Maxim N Artyomov, Elisha D O Roberson, Jonathan J Miner, and et al.
Late-season influenza vaccine effectiveness against medically attended outpatient illness, United States, December 2022-April 2023, Jessie R Chung, Stacey L House, Tara Curley, and et al.
Leveraging digital media to promote youth mental health: Flipping the script on social media-related risk, Jessica L Hamilton, John Torous, Hannah S Szlyk, Candice Biernesser, Kaylee P Kruzan, Michaeline Jensen, Jazmin Reyes-Portillo, Brian A Primack, Jamie Zelazny, and Paul Weigle
Mendelian segregation and high recombination rates facilitate genetic analyses in Cryptosporidium parvum, Abigail Kimball, Lisa Funkhouser-Jones, Wanyi Huang, Rui Xu, William H. Witola, and L. David Sibley
Migraine headache in patients with spontaneous coronary artery dissection: A report of the iSCAD Registry, Bryan J Wells, Kathryn Lindley, and et al.
MRI and pathology comparisons in Rasmussen's encephalitis: A multi-institutional examination of hemispherotomy outcomes relative to imaging and histological severity, Alexander Doherty, Kathleen Knudson, Christine Fuller, James L Leach, Anthony C Wang, Neena Marupudi, Rowland H Han, Stuart Tomko, Jeff Ojemann, Matthew D Smyth, Francesco Mangano, and Jesse Skoch
Naturalistic assessment of reaction time variability in older adults at risk for Alzheimer's disease, Matthew S Welhaf, Hannah Wilks, Andrew J Aschenbrenner, David A Balota, Suzanne E Schindler, Tammie L S Benzinger, Brian A Gordon, Carlos Cruchaga, Chengjie Xiong, John C Morris, and Jason Hassenstab
Paracrine signaling by pancreatic islet cilia, Samantha E Adamson and Jing W Hughes
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS, Madhurima Chatterjee, Nicolas R Barthélemy, Randall J Bateman, and et al.
Predictors of non-variceal hemorrhage in a national cohort of patients with chronic liver disease, Amber Afzal, Preethi Kesavan, Luo Suhong, Brian F Gage, Kevin Korenblat, Martin Schoen, and Kristen Sanfilippo
Proteolysis of the pericellular matrix: Pinpointing the role and involvement of matrix metalloproteinases in early osteoarthritic remodeling, Marina Danalache, Felix Umrath, Rosa Riester, Maik Schwitalle, Farshid Guilak, and Ulf Krister Hoffmann
Real-world experience with avacopan in antineutrophil cytoplasmic autoantibody-associated vasculitis, Reza Zonozi, Aisha Shaikh, Colin Diffie, and et al.
Retrospective multicenter cohort study on safety and electroencephalographic response to lacosamide for neonatal seizures, Moninder Kaur, Rejean M Guerriero, Renée A Shellhaas, and et al.
Safety of non-cuffed tunneled central venous catheters in adults with cystic fibrosis, Arshan Dehbozorgi, Badr Jandali, Robert Turner, Aaron Rohr, Brandon Custer, Kate Young, Carissa Walter, Lauren Clark, Yanming Li, Deepika Polineni, and Joel Mermis
SCMR Expert Consensus Statement for cardiovascular magnetic resonance of patients with a cardiac implantable electronic device, Daniel Kim, Pamela K Woodard, and et al.
Shared vision for improving outcomes for serious fungal diseases: Report of a patient, caregiver, and clinician summit, Rob Purdie, Lisa A Tushla, Jonathan Ferretti, Gonzalo Kiko Castro, Ricky Watson, Thomas Davis, Brianna Raborg, Patrick B Mazi, Angela Stroman, Carolynn Thomas Jones, Thomas J Walsh, Tom M Chiller, Peter G Pappas, John Meyer, and Andrej Spec
Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes, Kunal Jindal, Mohd Tayyab Adil, Naoto Yamaguchi, Xue Yang, Helen C Wang, Kenji Kamimoto, Guillermo C Rivera-Gonzalez, and Samantha A Morris
Skeletal abnormalities in mice with Dnmt3a missense mutations, Austin Bell-Hensley, Diana C Beard, Kathryn Feeney, Hongjun Zheng, Yunhao Jiang, Xiyun Zhang, Jin Liu, Harrison Gabel, and Audrey McAlinden
Spatially resolved metabolomic dataset of distinct human kidney anatomic regions, Haikuo Li and Benjamin D Humphreys
Subunit communication within dimeric SF1 DNA helicases, Binh Nguyen, John Hsieh, Christopher J Fischer, and Timothy M Lohman
Symptom characteristics, perceived causal attributions, and contextual factors influencing self-care behaviors: An ecological daily assessment study of adults with chronic illness, Barbara Riegel, Shayleigh Dickson Page, Subhash Aryal, Christopher S Lee, Andrew Belfiglio, Kenneth E Freedland, Anna Stromberg, Ercole Vellone, Heleen Westland, Michelle M van Rijn, Sara Pettersson, Douglas J Wiebe, and Tiny Jaarsma
Takotsubo syndrome in patients with COVID-19: A systematic review, Xiaojia Lu, Catherine Teng, Peng Cai, Jing Liang, Yanxuan Wang, Hawa Abu, Yuan Jia Wang, John E Madias, Kan Liu, Qi Liu, and Pengyang Li
The first reported case of treating the ultra-central thorax with cone beam computed tomography-guided stereotactic adaptive radiotherapy (CT-STAR), Stephanie Zhao, Robbie Beckert, Xiaodong Zhao, Eric Laugeman, Clifford G. Robinson, Gregory Vlacich, Pamela P. Samson, and Joshua P. Schiff
The impact of an Advanced Practice Radiation Therapist contouring for a CBCT-based adaptive radiotherapy program, Robbie Beckert, Joshua P Schiff, Eric Morris, Pamela Samson, Hyun Kim, and Eric Laugeman
Three-year outcomes of post-acute sequelae of COVID-19, Miao Cai, Yan Xie, Eric J Topol, and Ziyad Al-Aly
Transient cortical weakness following cerebral angiography: A new syndrome, Akash P Kansagra, Richard Pham, Arindam R Chatterjee, and Christopher J Moran
Use of a blood biomarker test improves economic utility in the evaluation of older patients presenting with cognitive impairment, William J Canestaro, Randall J Bateman, David M Holtzman, Mark Monane, and Joel B Braunstein
Validated clinical score to predict gastroesophageal reflux in patients with chronic laryngeal symptoms: COuGH RefluX, Amanda J Krause, Alexander M Kaizer, Dustin A Carlson, Walter W Chan, Chien-Lin Chen, C Prakash Gyawali, Andrew Jenkins, John E Pandolfino, Vinathi Polamraju, Ming-Wun Wong, Madeline Greytak, and Rena Yadlapati
Variation in North American infectious disease specialists' practice regarding oral and suppressive antibiotics for adult osteoarticular infections: Results of an Emerging Infections Network (EIN) survey, Nicolás Cortés-Penfield, Susan E Beekmann, Philip M Polgreen, Keenan Ryan, Jonas Marschall, and Poorani Sekar
Factors associated with incomplete resection for large, locally invasive non-small cell lung cancer, Whitney S. Brandt, Zhizhou Yang, Brendan T. Heiden, Pamela P. Samson, Daniel Morgensztern, Saiama N. Waqar, Bryan F. Meyers, Ruben G. Nava, G. Alexander Patterson, Benjamin D. Kozower, and Varun Puri
Propofol enhancement of slow wave sleep to target the nexus of geriatric depression and cognitive dysfunction: Protocol for a phase I open label trial, Rachel Lynn Rios, Michael Green, S Kendall Smith, MohammadMehdi Kafashan, ShiNung Ching, Nuri B Farber, Nan Lin, Brendan P Lucey, Charles F Reynolds, Eric J Lenze, Ben Julian Agustin Palanca, and SWIPED Study Team
TCAF1 promotes TRPV2-mediated Ca2+ release in response to cytosolic DNA to protect stressed replication forks, Lingzhen Kong, Chen Cheng, Abigael Cheruiyot, Jiayi Yuan, Yichan Yang, Sydney Hwang, Daniel Foust, Ning Tsao, Emily Wilkerson, Nima Mosammaparast, Michael B Major, David W Piston, Shan Li, and Zhongsheng You
The debranching enzyme Dbr1 regulates lariat turnover and intron splicing, Luke Buerer, Brittany A Townley, Nima Mosammaparast, and et al.
Induced CD8α identifies human NK cells with enhanced proliferative fitness and modulates NK cell activation, Celia C. Cubitt, Pamela Wong, Hannah K. Dorando, Jennifer A. Foltz, Jennifer Tran, Lynne Marsala, Nancy D. Marin, Mark Foster, Timothy Schappe, Hijab Fatima, Michelle Becker-Hapak, Alice Y. Zhou, Kimberly Hwang, Miriam T. Jacobs, David A. Russler-Germain, Emily M. Mace, Melissa M. Berrien-Elliott, Jacqueline E. Payton, and Todd A. Fehniger
LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD+ depletion, Ryo Terao, Tae Jun Lee, Jason Colasanti, Charles W Pfeifer, Joseph B Lin, Andrea Santeford, Keitaro Hase, Shinobu Yamaguchi, Daniel Du, Brian S Sohn, Yo Sasaki, Mitsukuni Yoshida, and Rajendra S Apte
Metabolic regulation of single synaptic vesicle exo- and endocytosis in hippocampal synapses, Jongyun Myeong, Marion I Stunault, Vitaly A Klyachko, and Ghazaleh Ashrafi
Nivolumab plus brentuximab vedotin for relapsed/refractory peripheral T-cell lymphoma and cutaneous T-cell lymphoma, Pier Luigi Zinzani, Neha Mehta-Shah, and et al.
Quantifying the effects of sleep on sensor-derived variables from upper limb accelerometry in people with and without upper limb impairment, Allison E Miller, Catherine E Lang, Marghuretta D Bland, and Keith R Lohse
Retrospective study on the efficacy and safety of dulaglutide in patients with diabetes and moderate-advanced chronic kidney disease, Sriya Kosaraju and Rong M Zhang
Safety and efficacy of metabolic modulation with ninerafaxstat in patients with nonobstructive hypertrophic cardiomyopathy, Martin S Maron, Sharon Cresci, and et al.
Using Structured Problem Solving to promote fluid consumption in the Prevention of Urinary Stones with Hydration (PUSH) trial, Peter P Reese, H Henry Lai, Alana C Desai, and et al.
Intrapartum exposure to synthetic oxytocin, maternal BMI, and neurodevelopmental outcomes in children within the ECHO consortium, Lisa Kurth, T Michael O'Shea, Irina Burd, Anne L Dunlop, Lisa Croen, Greta Wilkening, Ting-Ju Hsu, Stephan Ehrhardt, Arvind Palanisamy, Monica McGrath, Marie L Churchill, Daniel Weinberger, Marco Grados, and Dana Dabelea
Radiotherapy plan quality assurance in NRG oncology trials for brain and head/neck cancers: An AI-enhanced knowledge-based approach, Du Wang, Jeff M Michalski, Jiayi Huang, and et al.
Biobank-wide association scan identifies risk factors for late-onset Alzheimer's disease and endophenotypes, Donghui Yan, Carlos Cruchaga, and et al.
Effect of genomic and cellular environments on gene expression noise, Clarice K Y Hong, Avinash Ramu, Siqi Zhao, and Barak A Cohen
Accessibility, relevance, and impact of a symptom monitoring tool for home hospice care: Theory elaboration and qualitative assessment, Karla T Washington, Debra Parker Oliver, Allison K Donehower, Patrick White, Jacquelyn J Benson, Patrick G Lyons, and George Demiris
Health equity engineering: Optimizing hope for a new generation of healthcare, Felicity T Enders, Joyce E Balls-Berry, and et al.
Solutes unmask differences in clustering versus phase separation of FET proteins, Mrityunjoy Kar, Laura T Vogel, Gaurav Chauhan, Suren Felekyan, Hannes Ausserwöger, Timothy J Welsh, Furqan Dar, Anjana R Kamath, Tuomas P J Knowles, Anthony A Hyman, Claus A M Seidel, and Rohit V Pappu
Quantification of visceral fat at the L5 vertebral body level in patients with Crohn's disease using T2-weighted MRI, Favour Garuba, Aravinda Ganapathy, Spencer McKinley, Karan H Jani, Adriene Lovato, Satish E Viswanath, Scott McHenry, Parakkal Deepak, and David H Ballard
A fungal protein organizes both glycogen and cell wall glucans, Liza Loza and Tamara L Doering
Comprehensive proteogenomic characterization of rare kidney tumors, Ginny Xiaohe Li, Yize Li, Nataly Naser Al Deen, Feng Chen, Wagma Caravan, Andrew Houston, Siqi Chen, Li Ding, and et al.
Feasibility, acceptability and preliminary effect of a community-led HIV self-testing model among adolescent girls and young women in Rural Northern Uganda: A quasi-experimental study protocol, Ronald Olum, Elvin H Geng, Freddy E Kitutu, and Philippa M Musoke
Graded decisions in the human brain, Tao Xie, Markus Adamek, Hohyun Cho, Matthew A Adamo, Anthony L Ritaccio, Jon T Willie, Peter Brunner, and Jan Kubanek
Molecular insights into the prototypical single-stranded DNA-binding protein from E. coli, Nina J Bonde, Alexander G Kozlov, Michael M Cox, Timothy M Lohman, and James L Keck
Gilteritinib as post-transplant maintenance for AML with internal tandem duplication mutation of FLT3, Mark J Levis, Geoffrey L Uy, and et al.
Common single-base insertions in the VNTR of the carboxyl ester lipase (CEL) gene are benign and also likely to arise somatically in the exocrine pancreas, Ranveig S Brekke, Anny Gravdal, Khadija El Jellas, Grace E Curry, Jianguo Lin, Steven J Wilhelm, Solrun J Steine, Eric Mas, Stefan Johansson, Mark E Lowe, Bente B Johansson, Xunjun Xiao, Karianne Fjeld, and Anders Molven
Liver ACOX1 regulates levels of circulating lipids that promote metabolic health through adipose remodeling, Dongliang Lu, Anyuan He, Min Tan, Marguerite Mrad, Amal El Daibani, Donghua Hu, Xuejing Liu, Brian Kleiboeker, Tao Che, Fong-Fu Hsu, Monika Bambouskova, Clay F. Semenkovich, and Irfan J. Lodhi
The impact of behavior change counseling delivered via a digital health tool versus routine care among adolescents with obesity: Pilot randomized feasibility study, Maura Kepper, Callie Walsh-Bailey, Zoe M Miller, Min Zhao, Kianna Zucker, Angeline Gacad, Cynthia Herrick, Neil H White, Ross C Brownson, and Randi E Foraker
Benefits and advances of Cone Beam CT use in prostatic artery embolization: Review of the literature and pictorial essay, Nassir Rostambeigi, Daniel Crawford, and Jafar Golzarian
Quantitative T2 mapping-based longitudinal assessment of brain injury and therapeutic rescue in the rat following acute organophosphate intoxication, Alita Jesal D Almeida, Brad A Hobson, Naomi Saito, Donald A Bruun, Valerie A Porter, Danielle J Harvey, Joel R Garbow, Abhijit J Chaudhari, and Pamela J Lein
Unintentionally intentional: Unintended effects of spinal stimulation as a platform for multi-modal neurorehabilitation after spinal cord injury, Gerson N Moreno Romero, Avery R Twyman, Maria F Bandres, and Jacob Graves McPherson
Acute pulmonary injury in hematology patients supported with pathogen-reduced and conventional platelet components, Allison P Wheeler, Ronald Jackups, and et al.
Causes and attributable fraction of death from ARDS in inflammatory phenotypes of sepsis, Bruno Evrard, Pratik Sinha, and et al.
MV140 mucosal vaccine induces targeted immune response for enhanced clearance of uropathogenic E. coli in experimental urinary tract infection, Paula Saz-Leal, Marianne Morris Ligon, Carmen María Diez-Rivero, Diego García-Ayuso, Soumitra Mohanty, Marcos Viñuela, Irene Real-Arévalo, Laura Conejero, Annelie Brauner, José Luis Subiza, and Indira Uppugunduri Mysorekar
Radiological and pulmonary results of surgical treatment of severe idiopathic scoliosis using preoperative Halo gravity traction compared with less invasive temporary internal distraction in staged surgery in adolescents, Pawel Grabala, Michael A Galgano, Michal Grabala, and Jacob M Buchowski
Targeting cathepsin C ameliorates murine acetaminophen-induced liver injury, Jessica Raith, Malte Bachmann, Sina Gonther, Hendrik Stülb, Ali A Aghdassi, Christine T N Pham, and Heiko Mühl
Reverse genetics of murine rotavirus: A comparative analysis of the wild-type and cell-culture-adapted murine rotavirus VP4 in replication and virulence in neonatal mice, Takahiro Kawagishi, Liliana Sánchez-Tacuba, Ningguo Feng, Harry B Greenberg, and Siyuan Ding
Genome-wide epistatic network analyses of semantic fluency in older adults, Qihua Tan, Weilong Li, Marianne Nygaard, Ping An, Mary Feitosa, Mary K Wojczynski, Joseph Zmuda, Konstantin Arbeev, Svetlana Ukraintseva, Anatoliy Yashin, Kaare Christensen, and Jonas Mengel-From
