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Submissions from 2022

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Enteric pathogen testing importance for children with acute gastroenteritis: A modified Delphi study, Gillian A M Tarr, Drew J Persson, Phillip I Tarr, and Stephen B Freedman

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Epidemiology of plasmid lineages mediating the spread of extended-spectrum beta-lactamases among clinical Escherichia coli, Bejan Mahmud, Meghan A Wallace, Kimberly A Reske, Kelly Alvarado, Carol E Muenks, David A Rasmussen, Carey-Ann D Burnham, Cristina Lanzas, Erik R Dubberke, and Gautam Dantas

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Marijuana use and DNA methylation-based biological age in young adults, Drew R Nannini, Yinan Zheng, Brian T Joyce, Tao Gao, Lei Liu, David R Jacobs Jr, Pamela Schreiner, Chunyu Liu, Steve Horvath, Ake T Lu, Kristine Yaffe, Stephen Sidney, Philip Greenland, Donald M Lloyd-Jones, and Lifang Hou

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Self-renewal of macrophages: Tumor-released factors and signaling pathways, Serena Filiberti, Mariapia Russo, Silvia Lonardi, Mattia Bugatti, William Vermi, Cathy Tournier, and Emanuele Giurisato

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Discovery of a novel genomic alteration that renders leukemic cells resistant to CD19-targeted immunotherapies, Armin Ghobadi, Jack H Landmann, Alun Carter, Matthew L Cooper, Mehmet Emrah Selli, Jufang Chang, Christopher A Miller, Francesca Ferraro, David Y Chen, Amanda M Smith, Taylor A LaValle, Eric J Duncavage, Nathan Singh, and et al.

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Human neutrophil development and functionality are enabled in a humanized mouse model, Yunjiang Zheng, Esen Sefik, John Astle, Kutay Karatepe, Hasan H Öz, Angel G Solis, Ruaidhrí Jackson, Hongbo R Luo, Emanuela M Bruscia, Stephanie Halene, Liang Shan, and Richard A Flavell

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Novel chelating agents for zirconium-89-positron emission tomography (PET) imaging: Synthesis, DFT calculation, radiolabeling, and in vitro and in vivo complex stability, Chi Soo Kang, Shuyuan Zhang, Haixing Wang, Yujie Liu, Siyuan Ren, Yanda Chen, Jingbai Li, Nilantha Bandara, Andrey Yu Rogachev, Buck E Rogers, and Hyun-Soon Chong

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Pooled image-base screening of mitochondria with microraft isolation distinguishes pathogenic Mitofusin 2 mutations, Alex L Yenkin, John C Bramley, Colin L Kremitzki, Jason E Waligorski, Mariel J Liebeskind, Xinyuan E Xu, Vinay D Chandrasekaran, Maria A Vakaki, Graham W Bachman, Robi D Mitra, Jeffrey D Milbrandt, and William J Buchser

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Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics, Taylor M Nye, Hasan Tükenmez, Pardeep Singh, Ana L Flores-Mireles, Chloe L P Obernuefemann, Jerome S Pinkner, Souvik Sarkar, Mari Bonde, Anders E G Lindgren, Karen W Dodson, Jörgen Johansson, Fredrik Almqvist, Michael G Caparon, and Scott J Hultgren

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Somatic mutations in FAT cadherin family members constitute an underrecognized subtype of colorectal adenocarcinoma with unique clinicopathologic features, Liang-Li Wang, Wei Zheng, Xiu-Li Liu, and Feng Yin

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The impact of TSC-1 and -2 mutations on response to therapy in malignant PEComa: A multicenter retrospective analysis, Lawrence Liu, Nikhil Grandhi, Yang Lyu, Xiao Zhang, Jingqin Luo, Mia Weiss, Brian Van Tine, Angela C Hirbe, and et al.

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Personalized ctDNA micro-panels can monitor and predict clinical outcomes for patients with triple-negative breast cancer, Erica K Barnell, Bryan Fisk, Zachary L Skidmore, Kelsy C Cotto, Anamika Basu, Aparna Anand, Megan M Richters, Jingqin Luo, Catrina Fronick, Meenakshi Anurag, Robert Fulton, Matthew J Ellis, Obi L Griffith, Malachi Griffith, and Foluso O Ademuyiwa

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A randomized feasibility pilot-study of intravenous and subcutaneous administration of ketamine to prevent postpartum depression after planned cesarean delivery under neuraxial anesthesia, David Thomas Monks, Arvind Palanisamy, Danish Jaffer, Preet Mohinder Singh, Ebony Carter, and Shannon Lenze

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A comparison of bioimpedance analysis vs. dual x-ray absorptiometry for body composition assessment in postpartum women and non-postpartum controls, Valene Garr Barry, Samantha L Martin, Paula Chandler-Laney, Ebony B Carter, and Camille S Worthington

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Complete genome sequence of the uropathogenic methicillin-resistant Staphylococcus aureus strain MRSA-1369, Hasan Tükenmez, Taylor M Nye, Mari Bonde, Michael G Caparon, Fredrik Almqvist, Scott J Hultgren, and Jörgen Johansson

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Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults, Katrina L Kalantar, Pratik Sinha, and et al.

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Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma, Qing Kay Li, Daniel Cui Zhou, Yize Li, Rita Jui-Hsien Lu, Li Ding, and et al.

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Can the "female protective effect" liability threshold model explain sex differences in autism spectrum disorder?, Joseph D Dougherty, Natasha Marrus, Susan E Maloney, Benjamin Yip, Sven Sandin, Tychele N Turner, Din Selmanovic, Kristen L Kroll, David H Gutmann, John N Constantino, and Lauren A Weiss

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Semi-automated assembly of high-quality diploid human reference genomes, Erich D Jarvis, Sarah Cody, Robert S Fulton, Lucinda L Fulton, Daofeng Li, Tina Lindsay, Nathan O Stitziel, Ting Wang, and et al.

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Activity-dependent translation dynamically alters the proteome of the perisynaptic astrocyte process, Darshan Sapkota, Kristina Sakers, Kayla R Nygaard, Yating Liu, Sarah K Koester, Stuart B Fass, Allison M Lake, Rohan Khazanchi, Susan E Maloney, Joseph D Dougherty, and et al.

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Prenatal exposure to maternal social disadvantage and psychosocial stress and neonatal white matter connectivity at birth, Rachel E Lean, Christopher D Smyser, Rebecca G Brady, Regina L Triplett, Sydney Kaplan, Jeanette K Kenley, Joshua S Shimony, Tara A Smyser, J Phillip Miller, Deanna M Barch, Joan L Luby, Barbara B Warner, and Cynthia E Rogers

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A quantitative metric of pioneer activity reveals that HNF4A has stronger in vivo pioneer activity than FOXA1, Jeffrey L Hansen and Barak A Cohen

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Cellular landscaping of COVID-19 and gynaecological cancers: An infrequent correlation, Rahul Bhattacharjee, Debanjan Das, Radheka Bhadhuri, Srija Chakraborty, Tanima Dey, Rupam Buragohain, Asim Nath, Kartik Muduli, Pranjan Barman, and Rohit Gundamaraju

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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep, Hemanth R. Nelvagal, Sophie H. Wang, Elizabeth M. Eultgen, Keigo Takashash, Steven Q. Le, Rachel Nesbitt, Joshua T. Dearborn, Patricia I. Dickson, Mark S. Sands, Jonathan D. Cooper, and et al.

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IL-1β-dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction, Wenbin Yang, Daniel Kreisel, and et al.

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HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia, Qianze Dong, Nick Borcherding, and et al.

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BOLD cofluctuation 'events' are predicted from static functional connectivity, Zach Ladwig, Benjamin A. Seitzman, Ally Dworetsky, Yuhua Yu, Babatunde Adeyemo, Derek M. Smith, Steven E. Petersen, and Caterina Gratton

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Impact of the COVID-19 pandemic on the implementation of mobile health to improve the uptake of hydroxyurea in patients with sickle cell disease: Mixed methods study, Sherif M Badawy, Lisa DiMartino, Donald Brambilla, Lisa Klesges, Ana Baumann, Ebony Burns, Terri DeMartino, Sara Jacobs, Hamda Khan, Chinonyelum Nwosu, Nirmish Shah, Jane S Hankins, and Sickle Cell Disease Implementation Consortium

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Predicting postoperative troponin in patients undergoing elective hip or knee arthroplasty: A comparison of five cardiac risk prediction tools, Merih T Tesfazghi, Anne R Bass, Noor Al-Hammadi, Scott C Woller, Scott M Stevens, Charles S Eby, Mitchell G Scott, Lindsey Snyder, Troy S Wildes, and Brian F Gage

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Trial of Ultrasound guided carpal tunnel release versus Traditional Open Release (TUTOR), Kyle R. Eberlin, Christopher J. Dy, Mark D. Fischer, James L. Gluck, F. Thomas D. Kaplan, Thomas J. McDonald, Larry E. Miller, Alexander Palmer, Marc E. Walker, and James F. Watt

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Clinical and molecular response to tebentafusp in previously treated patients with metastatic uveal melanoma: A phase 2 trial, Richard D Carvajal, Leonel Hernandez-Aya, and et al.

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Personalized structural biology reveals the molecular mechanisms underlying heterogeneous epileptic phenotypes caused by de novo KCNC2 variants, Souhrid Mukherjee, Jonathan H Sheehan, and et al.

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Amyloid β, lipid metabolism, basal cholinergic system, and therapeutics in Alzheimer's disease, Victoria Campos-Peña, Pavel Pichardo-Rojas, Talía Sánchez-Barbosa, Emma Ortíz-Islas, Citlali Ekaterina Rodríguez-Pérez, Pedro Montes, Gerardo Ramos-Palacios, Daniela Silva-Adaya, Rafael Valencia-Quintana, Jorge Francisco Cerna-Cortes, and Danira Toral-Rios

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Association of α-klotho with subclinical carotid atherosclerosis in subjects with type 1 diabetes mellitus, Esmeralda Castelblanco, Marta Hernández, Nuria Alonso, Aina Ribes-Betriu, Jordi Real, Minerva Granado-Casas, Joana Rossell, Marina Idalia Rojo-López, Adriana Silvia Dusso, Josep Julve, and Didac Mauricio

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Collaborative quality improvement strategy in secondary prevention of cardiovascular disease in India: Findings from a multi-stakeholder, qualitative study using Consolidated Framework for Implementation Research (CFIR), Kavita Singh, Mark D. Huffman, Leslie C M Johnson, Nikhil Tandon, Dorairaj Prabhakaran, and Emily Mendenhall

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Mesoscale structure-function relationships in mitochondrial transcriptional condensates, Marina Feric, Azadeh Sarfallah, Furqan Dar, Dmitry Temiakov, Rohit V Pappu, and Tom Misteli

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Whole genome sequence analysis of blood lipid levels in >66,000 individuals, Margaret Sunitha Selvaraj, Lisa de Las Fuentes, Susan K. Dutcher, and et al.

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Blood culture utilization practices among febrile and/or hypothermic inpatients, Kap Sum Foong, Satish Munigala, Stephanie Kern-Allely, and David K Warren

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Occupational characteristics associated with SARS-CoV-2 infection in the UK Biobank during August-November 2020: A cohort study, Elizabeth L Yanik, Bradley A Evanoff, Ann Marie Dale, Yinjiao Ma, and Karen E Walker-Bone

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Cellular sources and neuroprotective roles of interleukin-10 in the facial motor nucleus after axotomy, Elizabeth M Runge, Deborah O Setter, Abhirami K Iyer, Eric J Regele, Felicia M Kennedy, Virginia M Sanders, and Kathryn J Jones

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Global variation in isolated posterior cruciate ligament reconstruction, Derrick M Knapik, Varun Gopinatth, Garrett R Jackson, Jorge Chahla, Matthew V Smith, Matthew J Matava, and Robert H Brophy

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Why tic severity changes from then to now and from here to there, Ann M Iverson and Kevin J Black

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A bioresorbable peripheral nerve stimulator for electronic pain block, Geumbee Lee, Emily Ray, Sabrina Genovese, Ying Yan, Arman Odabas, Umang Khandpur, Wilson Z Ray, Matthew R MacEwan, and et al.

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Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond, Nathan Gaddis, Arpana Agrawal, Paul W Jeffries, Kathleen Bucholz, Elliot C Nelson, Laura Bierut, and et al.

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Spontaneous activity patterns in human motor cortex replay evoked activity patterns for hand movements, Tomer Livne, DoHyun Kim, Nicholas V Metcalf, Lu Zhang, Lorenzo Pini, Gordon L Shulman, and Maurizio Corbetta

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Continuous NPWT regulates fibrosis in murine diabetic wound healing, Mengfan Wu, Dany Y Matar, Zhen Yu, Ziyu Chen, Samuel Knoedler, Brian Ng, Oliver A Darwish, Sadaf Sohrabi, Leigh Friedman, Valentin Haug, George F Murphy, Yuval Rinkevich, Dennis P Orgill, and Adriana C Panayi

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Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk, Xianyong Yin, Adam E Locke, Nathan O Stitziel, and et al.

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A Living Database of HIV Implementation Research (LIVE project): Protocol for rapid living reviews, Ingrid Eshun-Wilson, Nathan Ford, Noelle Le Tourneau, Stefan Baral, Sheree Schwartz, Christopher Kemp, and Elvin Geng

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Antidepressant use and its association with 28-day mortality in inpatients with SARS-CoV-2: Support for the FIASMA model against COVID-19, Nicolas Hoertel, Angela M Reiersen, Eric J Lenze, Bradley A Fritz, and et al.

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Unravelling the reservoirs for colonisation of infants with Campylobacter spp. in rural Ethiopia: Protocol for a longitudinal study during a global pandemic and political tensions, Arie H Havelaar, Mark J Manary, and et al.

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A non-canonical retina-ipRGCs-SCN-PVT visual pathway for mediating contagious itch behavior, Fang Gao, Jun Ma, Yao-Qing Yu, Xiao-Fei Gao, Yang Bai, Yi Sun, Juan Liu, Xianyu Liu, Devin M Barry, Steven Wilhelm, Tyler Piccinni-Ash, Na Wang, Dongyang Liu, Yan Hao, Jin-Jing Jia, Qianyi Yang, Johan van Nispen, Zhou-Feng Chen, and et al.

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Association between the Affordable Care Act Medicaid expansion and receipt of cardiac resynchronization therapy by race and ethnicity, Hunter Mwansa, Ibrahim Barry, Shannon M Knapp, Sula Mazimba, Elizabeth Calhoun, Nancy K Sweitzer, and Khadijah Breathett

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Global longitudinal strain and biomarkers of cardiac damage and stress as predictors of outcomes after transcatheter aortic valve implantation, Andrew S Perry, Nishath Quader, Alan Zajarias, and et al.

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Pan-cancer analysis reveals recurrent BCAR4 gene fusions across solid tumors, Andrew Nickless, Jin Zhang, Ghofran Othoum, Jace Webster, Matthew J Inkman, Emily Coonrod, Sherron Fontes, Emily B Rozycki, Christopher A Maher, and Nicole M White

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Current communication practices between obstetrics and gynecology residency applicants and program directors, Helen Kang Morgan, Abigail Ford Winkel, Karen George, Eric Strand, Erika Banks, Fiona Byrne, David Marzano, and Maya M Hammoud

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Effectiveness of the Ad26.COV2.S (Johnson & Johnson) coronavirus disease 2019 (COVID-19) vaccine for preventing COVID-19 hospitalizations and progression to high disease severity in the United States, Nathaniel M Lewis, Hilary M Babcock, Jennie H Kwon, and et al.

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Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG), Ami V Desai, Karen Gauvain, Amy E Armstrong, and et al.

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Reprogramming alveolar macrophage responses to TGF-β reveals CCR2+ monocyte activity that promotes bronchiolitis obliterans syndrome, Zhiyi Liu, Fuyi Liao, Jihong Zhu, Dequan Zhou, Gyu Seong Heo, Hannah P. Leuhmann, Davide Scozzi, Antanisha Parks, Ramsey Hachem, Derek E. Byers, Laneshia K. Tague, Hrishikesh S. Kulkarni, Marlene Cano, Brian W. Wong, Wenjun Li, Daniel Kreisel, Andrew E Gelman, and et al.

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Shared brain and genetic architectures between mental health and physical activity, Wei Zhang, Sarah E Paul, Anderson Winkler, Ryan Bogdan, and Janine D Bijsterbosch

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The transcription factor Bach2 negatively regulates murine natural killer cell maturation and function, Shasha Li, Michael D Bern, Benpeng Miao, Changxu Fan, Xiaoyun Xing, Takeshi Inoue, Sytse J Piersma, Ting Wang, Marco Colonna, Tomohiro Kurosaki, and Wayne M Yokoyama

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Acute glycogen synthase kinase-3 inhibition modulates human cardiac conduction, Gang Li, Brittany D Brumback, Lei Huang, David M Zhang, Tiankai Yin, Catherine E Lipovsky, Stephanie C Hicks, Jesus Jimenez, Patrick M Boyle, and Stacey L Rentschler

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Antimicrobial stewardship for sepsis in the intensive care unit: Survey of critical care and infectious diseases physicians, M Cristina Vazquez Guillamet, Jason P Burnham, Maria Pérez, Marin H Kollef, Constantine A Manthous, and Donna B Jeffe

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A saturated map of common genetic variants associated with human height, Loïc Yengo, E Warwick Daw, Lihua Wang, Mary F. Feitosa, Michael A. Province, Dabeeru C. Rao, Adam E. Locke, and et al.

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Calciphylaxis arising following bariatric surgery: A case series, Bethany Cucka, Bianca Biglione, Lauren Ko, Emily D Nguyen, Charbel C Khoury, Sagar U Nigwekar, Malcolm K Robinson, and Daniela Kroshinsky

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Choline, DHA, and diarrheal disease associated with growth faltering in a case-control study, Jenna N Diaz, Sherlie Jean Louis Dulience, Noah Wolthausen, Xuntian Jiang, Emmanuel Gyimah, Francesca J Marhône Pierre, F Matthew Kuhlmann, and Lora L Iannotti

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Clinical use of mean nocturnal baseline impedance and post-reflux swallow-induced peristaltic wave index for the diagnosis of gastro-esophageal reflux disease, Pierfrancesco Visaggi, Lucia Mariani, Federica Baiano Svizzero, Luca Tarducci, Andrea Sostilio, Marzio Frazzoni, Salvatore Tolone, Roberto Penagini, Leonardo Frazzoni, Linda Ceccarelli, Vincenzo Savarino, Massimo Bellini, Prakash C Gyawali, Edoardo V Savarino, and Nicola de Bortoli

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Comprehensive characterization of the multiple myeloma immune microenvironment using integrated scRNA-seq, CyTOF, and CITE-seq analysis, Lijun Yao, Reyka G Jayasinghe, Mark A Fiala, Michael C Wendl, Stephen T Oh, John F DiPersio, Ravi Vij, and Li Ding

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Congenital aneurysm of the muscular interventricular septum associated with bifascicular block, Hoang H. Nguyen and Patrick Y. Jay

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Early preclinical experience of a mixed reality ultrasound system with active GUIDance for NEedle-based interventions: The GUIDE study, David Bloom, Jamie N Colombo, Nathan Miller, Michael K Southworth, Christopher Andrews, Alexander Henry, William B Orr, Jonathan R Silva, and Jennifer N Avari Silva

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Evaluating brain damage in multiple sclerosis with simultaneous multi-angular-relaxometry of tissue, Biao Xiang, Jie Wen, Robert E Schmidt, Alexander L Sukstanskii, Daniel Mamah, Dmitriy A Yablonskiy, and Anne H Cross

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Evaluation challenges for the application of extended reality devices in medicine, Ryan Beams, Jennifer Silva, and et al.

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Functional characterization of enhancer activity during a long terminal repeat's evolution, Alan Y Du, Xiaoyu Zhuo, Vasavi Sundaram, Nicholas O Jensen, Hemangi G Chaudhari, Nancy L Saccone, Barak A Cohen, and Ting Wang

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Gynecologic oncology patient perspectives and knowledge on advance care planning: A quality improvement intervention, Sarah P. Huepenbecker, Sophia Lewis, Mark C. Valentine, Marguerite L. Palisoul, Premal H. Thaker, Andrea R. Hagemann, Carolyn K. McCourt, Katherine C. Fuh, Matthew A. Powell, David G. Mutch, and Lindsay M. Kuroki

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Health-related quality of life in older patients with heart failure from before to early after advanced surgical therapies: Findings from the SUSTAIN-IT study, Kathleen L. Grady, Justin Hartupee, and et al.

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High polygenic risk scores are associated with early age of onset of alcohol use disorder in adolescents and young adults at risk, John I Nurnberger Jr, Kathleen Bucholz, Laura Bierut, Vivia McCutcheon, Andrey P Anokhin, and et al.

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Impact of updated clinical practice guidelines on outpatient treatment for Clostridioides difficile infection and associated clinical outcomes, Erik R Dubberke, Justin T Puckett, Engels N Obi, Sachin Kamal-Bahl, Kaushal Desai, Bruce Stuart, and Jalpa A Doshi

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Incisionless targeted adeno-associated viral vector delivery to the brain by focused ultrasound-mediated intranasal administration, Dezhuang Ye, Jinyun Yuan, Yaoheng Yang, Yimei Yue, Zhongtao Hu, Siaka Fadera, and Hong Chen

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Ischemic dual papillary muscle rupture in a postpartum patient with vascular Ehlers-Danlos syndrome, J. Mark Erfe, Paul Devlin, Jonathan Rich, Lisa Wilsbacher, Daniel Schimmel, Patrick McCarthy, and Amit Pawale

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Lung allograft standardized histological analysis (LASHA) template: A research consensus proposal, Fiorella Calabrese, Chieh-Yu Lin, and et al.

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Margetuximab with retifanlimab as first-line therapy in HER2+/PD-L1+ unresectable or metastatic gastroesophageal adenocarcinoma: MAHOGANY cohort A, D. V. T. Catenacci, H. Park, and et al.

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Multi-modulated frequency domain high density diffuse optical tomography, Guy A. Perkins, Adam T. Eggebrecht, and Hamid Dehghani

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Neoadjuvant atezolizumab for resectable non-small cell lung cancer: An open-label, single-arm phase II trial, Jamie E Chaft, G Alexander Patterson, Saiama N Waqar, and et al.

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Neuroinflammation and COVID-19, Abigail Vanderheiden and Robyn S. Klein

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Newborn mid-upper arm circumference identifies low-birth weight and vulnerable infants: A secondary analysis, D Taylor Hendrixson, Patrick N Lasowski, Aminata Shamit Koroma, and Mark J Manary

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Paediatrician's guide to post-operative care for functionally univentricular CHD: A review, Christina Ronai, Sarosh P Batlivala, Quang-Tuyen Nguyen, Markus S Renno, Lindsay Arthur, Julie Glickstein, Jonathan N Johnson, Jacob R Miller, Carolyn A Altman, and Elif Seda Selamet Tierney

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Peristaltic pumps adapted for laminar flow experiments enhance in vitro modeling of vascular cell behavior, Javier Abello, Shreya Raghavan, Yvette Y. Yien, and Amber N. Stratman

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Phase Ib study of eprenetapopt (APR-246) in combination with pembrolizumab in patients with advanced or metastatic solid tumors, H Park and et al.

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Quantitative single-cell analysis of Leishmania major amastigote differentiation demonstrates variably extended expression of the lipophosphoglycan (LPG) virulence factor in different host cell types, Michael A. Mandell, Wandy L. Beatty, and Stephen M. Beverley

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Radiotherapy for elderly patients with glioblastoma: An assessment of hypofractionation and modern treatment techniques, Jennifer K. Matsui, Jiayi Huang, and et al.

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Six-year results from RELEVANCE: Lenalidomide plus rituximab (R2) versus rituximab-chemotherapy followed by rituximab maintenance in untreated advanced follicular lymphoma, Franck Morschhauser, Nancy L Bartlett, and et al.

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Stress radiography Is a reliable method to quantify posterior cruciate ligament insufficiency: A systematic review, J. Jared Guth, Robert H. Brophy, Matthew J. Matava, R. Garrett Steinmetz, and Matthew V. Smith

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Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors, Eriko Katsuta, Malgorzata Gil-Moore, Justine Moore, Mohamed Yousif, Alex A Adjei, Yi Ding, Justin Caserta, Carmen M Baldino, Kelvin P Lee, Irwin H Gelman, Kazuaki Takabe, and Mateusz Opyrchal

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Telomere biology disorders: Time for moving towards the clinic?, Luis F Z Batista, Inderjeet Dokal, and Roy Parker

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The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis, Alba Cortés, John Martin, Bruce A. Rosa, Klara A. Stark, Simon Clare, Catherine McCarthy, Katherine Harcourt, Cordelia Brandt, Charlotte Tolley, Trevor D. Lawley, Makedonka Mitreva, Matthew Berriman, Gabriel Rinaldi, and Cinzia Cantacessi

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The inner nuclear membrane protein NEMP1 supports nuclear envelope openings and enucleation of erythroblasts, Didier Hodzic, Jun Wu, Karen Krchma, Andrea Jurisicova, Yonit Tsatskis, Yijie Liu, Peng Ji, Kyunghee Choi, and Helen McNeill

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TNFR1 contributes to activation-induced cell death of pathological CD4+ T lymphocytes during ischemic heart failure, Vinay Kumar, Rachel Rosenzweig, Suman Asalla, Sarita Nehra, Sumanth D Prabhu, and Shyam S Bansal

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Treatment of stage I lung cancer detected by computed tomography screening, David S. Gierada, Yun Zhu Bai, Matthew B. Spraker, Anne Stilinovic, and Ruben G. Nava

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Variability in energy expenditure is much greater in males than females, Lewis G Halsey, Susan B Racette, and et al.

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Altered methylation pattern in EXOC4 is associated with stroke outcome: An epigenome-wide association study, Natalia Cullell, Carolina Soriano-Tárraga, and et al.

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A novel piggyback strategy for mRNA delivery exploiting adenovirus entry biology, Myungeun Lee, Paul J Rice-Boucher, Logan Thrasher Collins, Ernst Wagner, Lorenzo Aulisa, Jeffrey Hughes, and David T Curiel