Submissions from 2022
Online learning for infectious disease fellows-A needs assessment, Miguel A Chavez, Nathanial S Nolan, Emily Gleason, Saman Nematollahi, Emily Abdoler, and Gerome Escota
Performance of a multianalyte 'rule-out' assay in pregnant individuals with suspected preeclampsia, Maged M Costantine, Georges Macones, and et al
Prediction of patient outcomes through social determinants of health: The Pulmonary Hypertension Association Registry (PHAR) evaluation, Dan Grinnan, Murali Chakinala, and et al.
Projected effects of disruptions to human immunodeficiency virus (HIV) prevention services during the coronavirus disease 2019 pandemic among Black/African American men who have sex with men in an Ending the HIV Epidemic priority jurisdiction, Jennifer Labs, Amy S Nunn, Philip A Chan, S Bessey, Carolyn J Park, Brandon D L Marshall, Rupa R Patel, Leandro A Mena, and William C Goedel
PROPHETIC EU: Prospective identification of pneumonia in hospitalized patients in the intensive care unit in European and United States cohorts, Stephen P Bergin, Marin H Kollef, and et al.
Recurrent transcriptional responses in AML and MDS patients treated with decitabine, Pawan Upadhyay, Jeremy Beales, Nakul M Shah, Agata Gruszczynska, Christopher A Miller, Allegra A Petti, Sai Mukund Ramakrishnan, Daniel C Link, Timothy J Ley, and John S Welch
Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia, Srdan Verstovsek, Ruben Mesa, Moshe Talpaz, Jean-Jacques Kiladjian, Claire N. Harrison, Stephen T. Oh, Alessandro M. Vannucchi, Raajit Rampal, Bart L. Scott, Sarah A. Buckley, Adam R. Craig, Karisse Roman-Torres, and John O. Mascarenhas
Risk of early versus later rebleeding from dural arteriovenous fistulas with cortical venous drainage, Andrew J Durnford, Ridhima Guniganti, Akash P Kansagra, Gregory J Zipfel, and et al
Safety of onasemnogene abeparvovec for patients with spinal muscular atrophy 8.5 kg or heavier in a Global Managed Access Program, Deepa H Chand, Susan Mitchell, Rui Sun, Nicole LaMarca, Sandra P Reyna, and Thao Sutter
Single-dose intrathecal dorsal root ganglia toxicity of onasemnogene abeparvovec in cynomolgus monkeys, Francis Fonyuy Tukov, Keith Mansfield, Mark Milton, Emily Meseck, Kelley Penraat, Deepa Chand, and Andreas Hartmann
Technical note: Institutional solution of clinical cine MRI for tumor motion evaluation in radiotherapy, Taeho Kim, Yu Wu, Zhen Ji, H Michael Gach, Nels Knutson, Stacie Mackey, and Matthew Schmidt
The role of smoking and body mass index in mortality risk assessment for geriatric hip fracture patients, Ariana T. Meltzer-Bruhn, Garrett W. Esper, Christopher G. Herbosa, Abhishek Ganta, Kenneth A. Egol, and Sanjit R. Konda
Treatment patterns and standardized outcome assessments among patients with inflammatory conditions of the pouch in a prospective multicenter registry, Edward L Barnes, Parakkal Deepak, Poonam Beniwal-Patel, Laura Raffals, Maia Kayal, Marla Dubinsky, Shannon Chang, Peter D R Higgins, Jennifer I Barr, Joseph Galanko, Yue Jiang, Raymond K Cross, Millie D Long, and Hans H Herfarth
Unilateral Loss of Maxillary Molars in Young Mice Leads to Bilateral Condylar Adaptation and Degenerative Disease., Christopher Phillip Chen, Jiehua Zhang, Bin Zhang, Mohamed G Hassan, Kyle Hane, Caroline C Chen, Ana Alejandra Navarro Palacios, Sunil Kapila, Andrew H Jheon, and Alice F Goodwin
All-in-focus fine needle aspiration biopsy imaging based on Fourier ptychographic microscopy, Mingshu Liang, Cory Bernadt, Soon Boon Justin Wong, Changsoon Choi, Richard Cote, and Changhuei Yang
Enabling hotspot detection and public health response to the COVID-19 pandemic, Randi Foraker, Joshua Landman, Ian Lackey, Matthew D Haslam, Alison L Antes, and Dennis Goldfarb
Multisite learning of high-dimensional heterogeneous data with applications to opioid use disorder study of 15,000 patients across 5 clinical sites, Xiaokang Liu, Rui Duan, Chongliang Luo, Alexis Ogdie, Jason H Moore, Henry R Kranzler, Jiang Bian, and Yong Chen
The Novel Data Collection and Analytics Tools for Remote Patient Monitoring in Heart Failure (Nov-RPM-HF) trial: Protocol for a single-center prospective trial, Ankit Bhatia, Gregory Ewald, and Thomas Maddox
Comparability of clinical trials and spontaneous reporting data regarding COVID-19 vaccine safety, Chongliang Luo, Jingcheng Du, Adam Cuker, Ebbing Lautenbach, David A Asch, Gregory A Poland, Cui Tao, and Yong Chen
Detection of Bourbon virus-specific serum neutralizing antibodies in human serum in Missouri, USA, Gayan Bamunuarachchi, Houda Harastani, Paul W Rothlauf, Ya-Nan Dai, Ali Ellebedy, Daved Fremont, Sean P J Whelan, David Wang, and Adrianus C M Boon
Genomic surveillance of clinical Pseudomonas aeruginosa isolates reveals an additive effect of carbapenemase production on carbapenem resistance, Luke Diorio-Toth, Sidra Irum, Robert F Potter, Meghan A Wallace, Muhammad Arslan, Tehmina Munir, Saadia Andleeb, Carey-Ann D Burnham, and Gautam Dantas
Large comparative analyses of primate body site microbiomes indicate that the oral microbiome is unique among all body sites and conserved among nonhuman primates, Abigail E Asangba, Lawrence Mugisha, Joshua Rukundo, Rebecca J Lewis, Ali Halajian, Liliana Cortés-Ortiz, Randall E Junge, Mitchell T Irwin, Johan Karlson, Andrew Perkin, Mrinalini Watsa, Gideon Erkenswick, Karen L Bales, Dorothy L Patton, Anna J Jasinska, Eduardo Fernandez-Duque, Steven R Leigh, and Rebecca M Stumpf
PARIS and SPARTA: Finding the Achilles' heel of SARS-CoV-2, Viviana Simon, Ali H Ellebedy, and et al
Selective whole-genome amplification as a tool to enrich specimens with low Treponema pallidum genomic DNA copies for whole-genome sequencing, Charles M Thurlow, Sandeep J Joseph, Lilia Ganova-Raeva, Samantha S Katz, Lara Pereira, Cheng Chen, Alyssa Debra, Kendra Vilfort, Kimberly Workowski, Stephanie E Cohen, Hilary Reno, Yongcheng Sun, Mark Burroughs, Mili Sheth, Kai-Hua Chi, Damien Danavall, Susan S Philip, Weiping Cao, Ellen N Kersh, and Allan Pillay
Whole exome sequencing enhanced imputation identifies 85 metabolite associations in the Alpine CHRIS cohort, Eva König, Johannes Rainer, Vinicius Verri Hernandes, Giuseppe Paglia, Fabiola Del Greco M, Daniele Bottigliengo, Xianyong Yin, Lap Sum Chan, Alexander Teumer, Peter P Pramstaller, Adam E Locke, and Christian Fuchsberger
Human metapneumovirus phosphoprotein independently drives phase separation and recruits nucleoprotein to liquid-like bodies, Kerri Beth Boggs, Kearstin Edmonds, Nicolas Cifuentes-Munoz, Farah El Najjar, Conny Ossandón, McKenna Roe, Chao Wu, Carole L Moncman, Trevor P Creamer, Gaya K Amarasinghe, Daisy W Leung, and Rebecca Ellis Dutch
InvL, an invasin-like adhesin, is a type II secretion system substrate required for Acinetobacter baumannii uropathogenesis, Clay D Jackson-Litteken, Gisela Di Venanzio, Nguyen-Hung Le, Nichollas E Scott, Bardya Djahanschiri, Jesus S Distel, Evan J Pardue, Ingo Ebersberger, and Mario F Feldman
Isolation of a potently neutralizing and protective human monoclonal antibody targeting yellow fever virus, Michael P Doyle, Joseph R Genualdi, Adam L Bailey, Nurgun Kose, Christopher Gainza, Jessica Rodriguez, Kristen M Reeder, Christopher A Nelson, Prashant N Jethva, Rachel E Sutton, Robin G Bombardi, Michael L Gross, Justin G Julander, Daved H Fremont, Michael S Diamond, and James E Crowe
Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy, Kelsey L Krus, Amy Strickland, Yurie Yamada, Laura Devault, Robert E Schmidt, A Joseph Bloom, Jeffrey Milbrandt, and Aaron DiAntonio
Structure of a vaccine-induced, germline-encoded human antibody defines a neutralizing epitope on the SARS-CoV-2 spike N-terminal domain, Clara G Altomare, Daniel C Adelsberg, Juan Manuel Carreno, Iden A Sapse, Fatima Amanat, Ali H Ellebedy, Viviana Simon, Florian Krammer, and Goran Bajic
The phenylacetic acid catabolic pathway regulates antibiotic and oxidative stress responses in Acinetobacter, Anna J Hooppaw, Jenna C McGuffey, Gisela Di Venanzio, Juan C Ortiz-Marquez, Brent S Weber, Tasia Joy Lightly, Tim van Opijnen, Nichollas E Scott, Silvia T Cardona, and Mario F Feldman
The translational landscape of SARS-CoV-2-infected cells reveals suppression of innate immune genes, Maritza Puray-Chavez, Nakyung Lee, Kasyap Tenneti, Yiqing Wang, Hung R Vuong, Yating Liu, Amjad Horani, Tao Huang, Sean P Gunsten, James B Case, Wei Yang, Michael S Diamond, Steven L Brody, Joseph Dougherty, and Sebla B Kutluay
Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity, Bartosz Wiernicki, Sophia Maschalidi, Jonathan Pinney, Sandy Adjemian, Tom Vanden Berghe, Kodi S Ravichandran, and Peter Vandenabeele
Infants later diagnosed with autism have lower canonical babbling ratios in the first year of life, L D Yankowitz, J R Pruett Jr, N Marrus, K Botteron, J N Constantino, and et al.
A human single-neuron dataset for face perception, Runnan Cao, Chujun Lin, Nicholas J Brandmeir, and Shuo Wang
Dialysis service in the embattled Tigray region of Ethiopia: A call to action, Ephrem Berhe, Will Ross, Hale Teka, Hiluf Ebuy Abraha, and Lewis Wall
The gut microbiome-brain crosstalk in neurodegenerative diseases, Laura Ghezzi, Claudia Cantoni, Emanuela Rotondo, and Daniela Galimberti
Antigenic landscapes on Staphylococcus aureus pore-forming toxins reveal insights into specificity and cross-neutralization, Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Sergey Shulenin, Daisy W Leung, Richard A Alm, Rajan P Adhikari, Gaya K Amarasinghe, Michael L Gross, and M Javad Aman
A pathogenic mechanism associated with myopathies and structural birth defects involves TPM2-directed myogenesis, Jennifer McAdow, Shuo Yang, Tiffany Ou, Gary Huang, Matthew B. Dobbs, Christina A. Gurnett, Michael J. Greenberg, and Aaron N. Johnson
Blocking cell cycle progression through CDK4/6 protects against chronic kidney disease, Yosuke Osaki, Marika Manolopoulou, Alla V Ivanova, Nicholas Vartanian, Melanie Phillips Mignemi, Justin Kern, Jianchun Chen, Haichun Yang, Agnes B Fogo, Mingzhi Zhang, Cassianne Robinson-Cohen, and Leslie S. Gewin
Dissociation between individual differences in self-reported pain intensity and underlying fMRI brain activation, M E Hoeppli, H Nahman-Averbuch, W A Hinkle, E Leon, J Peugh, M Lopez-Sola, C D King, K R Goldschneider, and R C Coghill
Vitamin D treatment prevents uremia-induced reductions in aortic microRNA-145 attenuating osteogenic differentiation despite hyperphosphatemia, Natalia Carrillo-López, Sara Panizo, Maria Vittoria Arcidiacono, Sandra de la Fuente, Laura Martínez-Arias, Emerenziana Ottaviano, Catalina Ulloa, María Piedad Ruiz-Torres, Isabel Rodríguez, Jorge B Cannata-Andía, Manuel Naves-Díaz, and Adriana S Dusso
Activation of the rat α1β2ε GABAA receptor by orthosteric and allosteric agonists, Allison L Germann, Ariel B Burbridge, Spencer R Pierce, and Gustav Akk
Fine-tuning cardiac insulin-like growth factor 1 receptor signaling to promote health and longevity, Mahmoud Abdellatif, Tobias Pendl, Sebastian J Hofer, Moydul Islam, Abhinav Diwan, Tobias Eisenberg, Frank Madeo, and et al
Mechanism of voltage sensing in Ca2+- and voltage-activated K + (BK) channels, Willy Carrasquel-Ursulaez, Ignacio Segura, Ignacio Díaz-Franulic, Felipe Echeverría, Yenisleidy Lorenzo-Ceballos, Nicolás Espinoza, Maximiliano Rojas, Jose Antonio Garate, Eduardo Perozo, Osvaldo Alvarez, Fernando D Gonzalez-Nilo, Ramón Latorre, and Valeria Marquez-Miranda
Mechanisms of Transcranial Doppler Ultrasound phenotypes in paediatric cerebral malaria remain elusive., Nicole F O'Brien, Yudy Fonseca, Hunter C Johnson, Douglas Postels, Gretchen L Birbeck, Yamikani Chimalizeni, Karl B Seydel, Montfort Bernard Gushu, Tusekile Phiri, Sylvester June, Karen Chetcuti, Lorenna Vidal, Manu S Goyal, and Terrie E Taylor
Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus, Jeffrey Downey, Haley E Randolph, Erwan Pernet, Kim A Tran, Shabaana A Khader, Irah L King, Luis B Barreiro, and Maziar Divangahi
mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes, Ofer Zimmerman, Alexa Michelle Altman Doss, Paulina Kaplonek, Chieh-Yu Liang, Laura A. VanBlargan, Rita E. Chen, Jennifer Marie Monroy, H. James Wedner, Anthony Kulczycki, Tarisa L. Mantia, Caitlin C. O'Shaughnessy, Hannah G. Davis-Adams, Harry L. Bertera, Lucas J. Adams, Saravanan Raju, Fang R. Zhao, Christopher J. Rigell, Tiffany Biason Dy, Andrew L. Kau, Zhen Ren, Jackson S. Turner, Jane A. O'Halloran, Rachel M. Presti, Daved H. Fremont, Peggy L. Kendall, Ali H. Ellebedy, Galit Alter, and Michael S. Diamond
Mycobacterium tuberculosis infection drives a type I IFN signature in lung lymphocytes, Sadia Akter, Kuldeep S Chauhan, Micah D Dunlap, José Alberto Choreño-Parra, Lan Lu, Ekaterina Esaulova, Joaquin Zúñiga, Maxim N Artyomov, Deepak Kaushal, and Shabaana A Khader
Face identity coding in the deep neural network and primate brain, Jinge Wang, Runnan Cao, Nicholas J Brandmeir, Xin Li, and Shuo Wang
Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke, Annie R Bice, Qingli Xiao, Justin Kong, Ping Yan, Zachary Pollack Rosenthal, Andrew W Kraft, Karen P Smith, Tadeusz Wieloch, Jin-Moo Lee, Joseph P Culver, and Adam Q Bauer
Impact of capsulectomy type on post-explantation systemic symptom improvement: Findings from the ASERF systemic symptoms in Women-Biospecimen Analysis Study: Part 1, Caroline Glicksman, Patricia McGuire, Marshall Kadin, Marisa Lawrence, Melinda Haws, Jill Newby, Sarah Ferenz, James Sung, and Roger Wixtrom
Rapid detection of an Ebola biomarker with optical microring resonators, Abraham J Qavi, Krista Meserve, M Javad Aman, Hong Vu, Larry Zeitlin, John M Dye, Jeffrey W Froude, Daisy W Leung, Lan Yang, Frederick W Holtsberg, Ryan C Bailey, and Gaya K Amarasinghe
Stroke recovery phenotyping through network trajectory approaches and graph neural networks, Sanjukta Krishnagopal, Keith Lohse, and Robynne Braun
Aspartyl protease inhibitors as anti-filarial drugs, Liana Beld, Hyeim Jung, Christina A Bulman, Bruce A Rosa, Peter U Fischer, James W Janetka, Sara Lustigman, Judy A Sakanari, and Makedonka Mitreva
Imaging peripheral nerve micro-anatomy with MUSE, 2D and 3D approaches, Chaitanya Kolluru, Austin Todd, Aniruddha R Upadhye, Yehe Liu, Mikhail Y Berezin, Farzad Fereidouni, Richard M Levenson, Yanming Wang, Andrew J Shoffstall, Michael W Jenkins, and David L Wilson
Protocol to analyze and quantify protein-methylated RNA interactions in mammalian cells with a combination of RNA immunoprecipitation and nucleoside mass spectrometry, Ning Tsao, Jennifer M Soll, and Nima Mosammaparast
Cryo-EM structure of the prothrombin-prothrombinase complex, Eliza A Ruben, Brock Summers, Michael J Rau, James A J Fitzpatrick, and Enrico Di Cera
A dual-center cohort study on the association between early deep sedation and clinical outcomes in mechanically ventilated patients during the COVID-19 pandemic: The COVID-SED study, Robert J Stephens, Erin M Evans, Michael J Pajor, Ryan D Pappal, Haley M Egan, Max Wei, Hunter Hayes, Jason A Morris, Nicholas Becker, Brian W Roberts, Marin H Kollef, Nicholas M Mohr, and Brian M Fuller
CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease, Jeremy F. Strain, Nicolas Barthelemy, Kanta Horie, Brian A. Gordon, Collin Kilgore, Andrew Aschenbrenner, Carlos Cruchaga, Chengjie Xiong, Nelly Joseph-Mathurin, Jason Hassenstab, Anne M. Fagan, Yan Li, Celeste M. Karch, Richard J. Perrin, Sarah B. Berman, Jasmeer P. Chhatwal, Neill R. Graff-Radford, Hiroshi Mori, Johannes Levin, James M. Noble, Ricardo Allegri, Peter R. Schofield, Daniel S. Marcus, David M. Holtzman, John C. Morris, Tammie L. S. Benzinger, Eric M. McDade, Randall J. Bateman, and Beau M. Ances
Piperine derivatives enhance fusion and axonal transport of mitochondria by activating mitofusins, Lihong Zhang, Xiawei Dang, Antonietta Franco, Haiyang Zhao, and Gerald W. Dorn II
The CSF in neurosarcoidosis contains consistent clonal expansion of CD8 T cells, but not CD4 T cells, Michael A Paley, Brandi J Baker, S Richard Dunham, Nicole Linskey, Claudia Cantoni, Kenneth Lee, Lynn M Hassman, Jennifer Laurent, Elisha D O Roberson, David B Clifford, and Wayne M Yokoyama
The microbiome restrains melanoma bone growth by promoting intestinal NK and Th1 cell homing to bone, Subhashis Pal, Daniel S. Perrien, Tetsuya Yumoto, Roberta Faccio, Andreea Stoica, Jonathan Adams, Craig M. Coopersmith, Rheinallt M. Jones, M. Neale Weitzmann, and Roberto Pacifici
68Ga-labeled benzothiazole derivatives for imaging Aβ plaques in cerebral amyloid angiopathy, Truc T Huynh, Yujue Wang, Karna Terpstra, Hong-Jun Cho, Liviu M Mirica, and Buck E Rogers
Distributed learning for heterogeneous clinical data with application to integrating COVID-19 data across 230 sites, Jiayi Tong, Chongliang Luo, Md Nazmul Islam, Natalie E Sheils, John Buresh, Mackenzie Edmondson, Peter A Merkel, Ebbing Lautenbach, Rui Duan, and Yong Chen
Exploring the impact of TREM2 in tumor-associated macrophages, Darya Khantakova, Simone Brioschi, and Martina Molgora
Impact of web-based cognitive behavioral therapy for insomnia on stress, health, mood, cognitive, inflammatory, and neurodegenerative outcomes in rural dementia caregivers: Protocol for the NiteCAPP CARES and NiteCAPP SHARES randomized controlled trial, Christina S McCrae, Ashley F Curtis, Amelia Cottle, David B Beversdorf, Joel Shenker, Brian P Mooney, Mihail Popescu, Marilyn Rantz, Maureen Groer, Phyllis Stein, Mojgan Golzy, Melanie A Stearns, Angelynn Simenson, Neetu Nair, and Meredeth A Rowe
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication, Marco Gargaro, Carlos G. Briseño, Prachi Bagadia, Vivek Durai, Derek J. Theisen, Sunkyung Kim, Marco Colonna, Theresa L. Murphy, Kenneth M. Murphy, and et al.
Metabolic biomarkers assessed with PET/CT predict sex-specific longitudinal outcomes in patients with diffuse large B-cell lymphoma, Shama Jaswal, Vanessa Sanders, Priyanka Pullarkat, Stephanie Teja, Amber Salter, Marcus P Watkins, Norman Atagu, Daniel R Ludwig, Joyce Mhlanga, Vincent M Mellnick, Linda R Peterson, Nancy L Bartlett, Brad S Kahl, Todd A Fehniger, Armin Ghobadi, Amanda F Cashen, Neha Mehta-Shah, and Joseph E Ippolito
The challenges of interrogating adipose tissue extracellular vesicle functions in physiology, Clair Crewe
A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activity, Miriam Y Kim, Reyka Jayasinghe, Jessica M Devenport, Julie K Ritchey, Michael P Rettig, Julie O'Neal, Karl W Staser, Krista M Kennerly, Alun J Carter, Feng Gao, Byung Ha Lee, Matthew L Cooper, and John F DiPersio
Assessing COVID-19 testing strategies in K-12 schools in underserved populations: Study protocol for a cluster-randomized trial, Samantha Hayes, Sara Malone, Brittany Bonty, Nancy Mueller, Summer M Reyes, Sydney A Reyes, Christina Evans, Myisha Wilcher-Roberts, Tremayne Watterson, Sewuese Akuse, Jamee Shelley, Grace Yuan, Ian Lackey, Jasmine Prater, Brock Montgomery, Cynthia Williams, Sheretta T Butler-Barnes, Kelly Harris, Charlene Caburnay, Nikole Lobb Dougherty, Jingxia Liu, Albert Lai, Julie Neidich, Stephanie Fritz, and Jason G Newland
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals, Thomas W. Winkler, E Warwick Daw, Mary F. Feitosa, Mary K. Wojczynski, Michael A. Province, and et al
Primary prevention of stroke in children with sickle cell anemia in Nigeria: Protocol for a mixed methods implementation study in a community hospital, Halima Bello-Manga, Lawal Haliru, Kudrat Abdulkareem Ahmed, Abdulkadir Musa Tabari, Bilkisu Usman Farouk, Gloria Yimi Bahago, Aisha Shuaibu Kazaure, Abdulrasheed Sani Muhammad, Samira Abubakar Gwarzo, Ana A Baumann, Michael R DeBaun, and Allison A King
Antigen glycosylation regulates efficacy of CAR T cells targeting CD19, Amanda Heard, Jack H Landmann, Ava R Hansen, Yu-Sung Hsu, Mehmet Emrah Selli, John M Warrington, John Lattin, Jufang Chang, Helen Ha, Balraj Doray, Abby M Green, Nathan Singh, and et al
A reference tissue atlas for the human kidney, Jens Hansen, Sanjay Jain, and et al
Phase I study of safety, tolerability, and efficacy of tebentafusp using a step-up dosing regimen and expansion in patients with metastatic uveal melanoma, Richard D Carvajal, Paul Nathan, Joseph J Sacco, Marlana Orloff, Leonel F Hernandez-Aya, Jessica Yang, Jason J Luke, Marcus O Butler, Sarah Stanhope, Laura Collins, Cheryl McAlpine, Chris Holland, Shaad E Abdullah, and Takami Sato
Blimp-1 molds the epigenetic architecture of IL-21-mediated autoimmune diseases through an autoregulatory circuit, Yu-Wen Liu, Shin-Huei Fu, Ming-Wei Chien, Chao-Yuan Hsu, Ming-Hong Lin, Jia-Ling Dong, Rita Jui-Hsien Lu, Yi-Jing Lee, Pao-Yang Chen, Chih-Hung Wang, and Huey-Kang Sytwu
Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19, Fuhai Li, Adrianus C M Boon, Andrew P Michelson, Randi E Foraker, Ming Zhan, and Philip R O Payne
Prostate cancer therapy personalization via multi-modal deep learning on randomized phase III clinical trials, Andre Esteva, Jeff M Michalski, and et al
Social determinants of health and cancer screening implementation and outcomes in the USA: A systematic review protocol, Ariella R Korn, Callie Walsh-Bailey, Meagan Pilar, Brittney Sandler, Prema Bhattacharjee, W Todd Moore, Ross C Brownson, Karen M Emmons, and April Y Oh
Neutrophil-to-lymphocyte ratios in patients undergoing aortic valve replacement: The PARTNER trials and registries, Bahira Shahim, Alan Zajarias, and et al
Political environment and mortality rates in the United States, 2001-19: Population based cross sectional analysis, Haider J Warraich, Pankaj Kumar, Khurram Nasir, Karen E Joynt Maddox, and Rishi K Wadhera
Potential impact of 2017 American College of Cardiology/American Heart Association Hypertension Guideline on contemporary practice: A cross-sectional analysis from NCDR PINNACLE Registry, Aliza Hussain, Salim S Virani, Luke Zheng, Ty J Gluckman, William B Borden, Frederick A Masoudi, and Thomas M Maddox
Precise topology of adjacent domain-general and sensory-biased regions in the human brain, Moataz Assem, Sneha Shashidhara, Matthew F Glasser, and John Duncan
Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome: A multicenter retrospective study, Sabrina Berens, Gregory Sayuk, and Et al
The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4, Wei-Le Wang, Jun Kasamatsu, Satoru Joshita, Susan Gilfillan, Blanda Di Luccia, Santosh K Panda, Do-Hyun Kim, Pritesh Desai, Jennifer K Bando, Stanley Ching-Cheng Huang, Kentaro Yomogida, Steven J Van Dyken, Marina Cella, Marco Colonna, and et al
The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4 eosinophils unique to the small intestine, Wei-Le Wang, Jun Kasamatsu, Satoru Joshita, Susan Gilfillan, Blanda Di Luccia, Santosh K Panda, Do-Hyun Kim, Pritesh Desai, Jennifer K Bando, Stanley Ching-Cheng Huang, Kentaro Yomogida, Steven J Van Dyken, Marina Cella, Marco Colonna, and Et al
Biophysical physiology of phosphoinositide rapid dynamics and regulation in living cells, Jill B Jensen, Bjoern H Falkenburger, Eamonn J Dickson, Lizbeth de la Cruz, Gucan Dai, Jongyun Myeong, Seung-Ryoung Jung, Martin Kruse, Oscar Vivas, Byung-Chang Suh, and Bertil Hille
Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures, Peter Georgeson, Yin Cao, and et al
Prefrontal cortex supports speech perception in listeners with cochlear implants, Arefeh Sherafati, Noel Dwyer, Aahana Bajracharya, Mahlega Samira Hassanpour, Adam T Eggebrecht, Jill B Firszt, Joseph P Culver, and Jonathan E Peelle
Quantifying concordant genetic effects of de novo mutations on multiple disorders, Hanmin Guo, Lin Hou, Yu Shi, Sheng Chih Jin, Xue Zeng, Boyang Li, Richard P Lifton, Martina Brueckner, Hongyu Zhao, and Qiongshi Lu
What is the state of children's participation in qualitative research on health interventions?: A scoping study, Jean M Hunleth, Julie S Spray, Corey Meehan, Colleen Walsh Lang, and Janet Njelesani
Molecular imaging phenotyping for selecting and monitoring radioligand therapy of neuroendocrine neoplasms, Amir Iravani, Ashwin Singh Parihar, Timothy Akhurst, and Rodney J Hicks
Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain, Laurel Mydock-McGrane, Kathiresan Krishnan, Douglas F Covey, and et al
Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes, Catherine J Greene, Jenny A Nguyen, Samuel M Cheung, Corey R Arnold, Dale R Balce, Ya Ting Wang, Adrian Soderholm, Neil McKenna, Devin Aggarwal, Rhiannon I Campden, Benjamin W Ewanchuk, Herbert W Virgin, and Robin M Yates
Optimizing allocation of curricular content across the undergraduate & graduate medical education continuum, Samara B Ginzburg, Margaret M Hayes, Brittany L Ranchoff, Eva Aagaard, Katharyn M Atkins, Michelle Barnes, Jennifer B Soep, Andrew C Yacht, Erik K Alexander, and Richard M Schwartzstein
RAISING is a high-performance method for identifying random transgene integration sites, Yusaku Wada, Ariella L G Coler-Reilly, and et al
22q11.2 Deletion Syndrome - A series of patients with midline skull base defects, Spencer S. Souza, Lia Jacobson, Dylan Chan, Anna Meyer, Jarod L. Roland, and Kimberly Luu
Accuracy of chest computed tomography in distinguishing cystic pleuropulmonary blastoma from benign congenital lung malformations in children, Abigail J Engwall-Gill, Jacqueline M Saito, Rebecca L Hulett Bowling, and et al.
