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Submissions from 2021

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Outcomes of rescue endovascular treatment of emergent large vessel occlusion in patients with underlying intracranial atherosclerosis: Insights from STAR, Sami Al Kasab, Joshua Osbun, and et al

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Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening, Shafqat A Khan, Kyoung-Mi Park, Laura A Fischer, Chen Dong, Tenzin Lungjangwa, Marta Jimenez, Dominick Casalena, Brian Chew, Sabine Dietmann, Douglas S Auld, Rudolf Jaenisch, and Thorold W Theunissen

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Prognostic factors for chronic post-surgical pain after lung or pleural surgery: A protocol for a systematic review and meta-analysis, Pascal Richard David Clephas, Sanne Elisabeth Hoeks, Marialena Trivella, Christian S Guay, Preet Mohinder Singh, Markus Klimek, and Michael Heesen

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GPS driving: A digital biomarker for preclinical Alzheimer disease, Sayeh Bayat, Ganesh M Babulal, Suzanne E Schindler, Anne M Fagan, John C Morris, Alex Mihailidis, and Catherine M Roe

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A phase 2a randomized clinical trial of intravenous vedolizumab for the treatment of steroid-refractory intestinal acute graft-versus-host disease, Yngvar Fløisand, Mark A Schroeder, Patrice Chevallier, Dominik Selleslag, Steven Devine, Anne S Renteria, Mohamad Mohty, Ibrahim Yakoub-Agha, Chunlin Chen, Andrejus Parfionovas, Syed Quadri, Johan Jansson, Mona Akbari, and Yi-Bin Chen

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Inferring TF activities and activity regulators from gene expression data with constraints from TF perturbation data, Cynthia Z Ma and Michael R Brent

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A strong effect of individual compliance with mass drug administration for lymphatic filariasis on sustained clearance of soil-transmitted helminth infections, Jérémy T Campillo, Naomi P Awaca-Uvon, Jean-Paul Tambwe, Godefroy Kuyangisa-Simuna, Johnny Vlaminck, Gary J Weil, Michel Boussinesq, Cédric B Chesnais, and Sébastien D S Pion

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Balancing serendipity and reproducibility: Pluripotent stem cells as experimental systems for intellectual and developmental disorders, Nickesha C Anderson, Pin-Fang Chen, Kesavan Meganathan, Wardiya Afshar Saber, Andrew J Petersen, Anita Bhattacharyya, Kristen L Kroll, Mustafa Sahin, and Cross-IDDRC Human Stem Cell Working Group

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Teaching scripts via smartphone app facilitate resident-led teaching of medical students, Nicholas R Zessis, Amanda R Dube, Arhanti Sadanand, Jordan J Cole, Christine M Hrach, and Yasmeen N Daud

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Destination shapes antibiotic resistance gene acquisitions, abundance increases, and diversity changes in Dutch travelers, Alaric W D'Souza, Manish Boolchandani, Sanket Patel, Gianluca Galazzo, Jarne M van Hattem, Maris S Arcilla, Damian C Melles, Menno D de Jong, Constance Schultsz, COMBAT Consortium, Gautam Dantas, and John Penders

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Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences, Liron Ganel, Lei Chen, Ryan Christ, Erica Young, Indraniel Das, Krishna Kanchi, David Larson, Allison Regier, Haley Abel, Chul Joo Kang, Alexandra Scott, Adam Locke, Nathan O Stitziel, Ira M Hall, and et al

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Soluble P-tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau, Niklas Mattsson-Carlgren, Shorena Janelidze, Randall J Bateman, Ruben Smith, Erik Stomrud, Geidy E Serrano, Eric M Reiman, Sebastian Palmqvist, Jeffrey L Dage, Thomas G Beach, and Oskar Hansson

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Sequence determinants of in cell condensate morphology, dynamics, and oligomerization as measured by number and brightness analysis, Ryan J Emenecker, Alex S Holehouse, and Lucia C Strader

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RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease, Robyn Laura Kosinsky, Maria Zerche, Rodney D Newberry, and et al

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A case of hepatic cyst-induced internal jugular venous thrombosis, Tuyen V Le, Thai Truong, Tam N M Ngo, Quoc Bui, Cassady Palmer, Vien T Truong, and Duc H Nguyen

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Addressing cancer survivors' cardiovascular health using the Automated Heart Health Assessment (AH-HA) EHR tool: Initial protocol and modifications to address COVID-19 challenges, Randi E Foraker, Eleanor C Davidson, Emily V Dressler, Brian J Wells, Simon Craddock Lee, Heidi D Klepin, Karen M Winkfield, W Gregory Hundley, Philip R O Payne, Albert M Lai, Glenn J Lesser, and Kathryn E Weaver

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A peptide-based checkpoint immunomodulator alleviates immune dysfunction in murine polymicrobial sepsis, Timothy W Phares, Vinayaka Kotraiah, Chun-Shiang Chung, Jacqueline Unsinger, Monty Mazer, Kenneth E. Remy, Cecille D. Browne, Peter Buontempo, Marc Mansour, James Pannucci, Alfred Ayala, Richard S. Hotchkiss, and Gabriel M. Gutierrez

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Association of clinical factors and recent anticancer therapy with COVID-19 severity among patients with cancer: A report from the COVID-19 and Cancer Consortium, P Grivas, K E Stockerl-Goldstein, A Y Zhou, and et al.

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Brain-responsive neurostimulation for the treatment of adults with epilepsy in tuberous sclerosis complex: A case series, Danielle S McDermott, Emily A Mirro, Kirsten Fetrow, David E Burdette, Stephanie Chen, Jennifer Hopp, Todd Masel, Emily A Johnson, Felicia M K Elefant, Scheherazade Le, Sanjay E Patra, Mesha-Gay Brown, and Zulfi Haneef

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Cardiac safety of trabectedin monotherapy or in combination with pegylated liposomal doxorubicin in patients with sarcomas and ovarian cancer, Robin L Jones, Thomas J Herzog, Shreyaskumar R Patel, Margaret von Mehren, Scott M Schuetze, Brian A Van Tine, Robert L Coleman, Roland Knoblauch, Spyros Triantos, Peter Hu, Waleed Shalaby, Tracy McGowan, Bradley J Monk, and George D Demetri

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Cardiovascular adverse events associated with BRAF versus BRAF/MEK inhibitor: Cross-sectional and longitudinal analysis using two large national registries, Avirup Guha, Prantesh Jain, Michael G Fradley, Daniel Lenihan, Jahir M Gutierrez, Chhavi Jain, Marcos de Lima, Jill S Barnholtz-Sloan, Guilherme H Oliveira, Afshin Dowlati, and Sadeer Al-Kindi

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Cervical cancer screening outcomes in Zambia, 2010-19: A cohort study, Jake M Pry, Albert Manasyan, Sharon Kapambwe, Katayoun Taghavi, Miquel Duran-Frigola, Mulindi Mwanahamuntu, Izukanji Sikazwe, Jane Matambo, Jack Mubita, Kennedy Lishimpi, Kennedy Malama, and Carolyn Bolton Moore

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Clinical epigenomics: Genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders, Bekim Sadikovic, Jorge L Granadillo, and et al.

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Clinical implications of estimated glomerular filtration rate dip following sodium-glucose cotransporter-2 inhibitor initiation on cardiovascular and kidney outcomes, Yan Xie, Benjamin Bowe, Andrew K Gibson, Janet B McGill, Geetha Maddukuri, and Ziyad Al-Aly

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Commonalities across computational workflows for uncovering explanatory variants in undiagnosed cases, Shilpa Nadimpalli Kobren, Dustin Baldridge, Daniel J Wegner, Alexander J Paul, and et al.

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Effects of pathogen reduction technology and storage duration on the ability of cryoprecipitate to rescue induced coagulopathies in vitro, Kimberly A Thomas, Susan M Shea, and Philip C Spinella

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Elevated mRNA expression and defective processing of cathepsin D in HeLa cells lacking the mannose 6-phosphate pathway, Lin Liu and Balraj Doray

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Epidemic preparedness: Prenatal Zika virus screening during the next epidemic, Luxi Qiao, Celina M Turchi Martelli, Amber I Raja, Nuria Sanchez Clemente, Thalia Velho Barreto de Araùjo, Ricardo Arraes de Alencar Ximenes, Demócrito de Barros Miranda-Filho, Anna Ramond, and Elizabeth B Brickley

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Evaluation of serum-derived bovine immunoglobulin protein isolate in subjects with decompensated cirrhosis with ascites, Matthew J. Stotts, Amanda Cheung, Muhammad B. Hammami, David J. Westrich Jr., Eric Anderson, Lauren Counts, Alex S. Befeler, Adrian M. Di Bisceglie, and Charlene Prather

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Examination of a blood-brain barrier targeting β-galactosidase-monoclonal antibody fusion protein in a murine model of GM1-gangliosidosis, Michael J Przybilla, Christine Stewart, Timothy W Carlson, Li Ou, Brenda L Koniar, Rohini Sidhu, Pamela J Kell, Xuntian Jiang, Jeanine R Jarnes, M Gerard O'Sullivan, and Chester B Whitley

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Integration of immunotherapy into adjuvant therapy for resected non-small-cell lung cancer: ALCHEMIST chemo-IO (ACCIO), Jacob M Sands, Ramaswamy Govindan, Jhanelle Gray, and et al

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Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels, Chris McKennan, Katherine Naughton, Catherine Stanhope, Meyer Kattan, George T O'Connor, Megan T Sandel, Cynthia M Visness, Robert A Wood, Leonard B Bacharier, Avraham Beigelman, Stephanie Lovinsky-Desir, Alkis Togias, James E Gern, Dan Nicolae, and Carole Ober

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MalDA, accelerating malaria drug discovery, Tuo Yang, Eva S. Istvan, Daniel E. Goldberg, and et al.

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Multiparametric early detection and prediction of cardiotoxicity using myocardial strain, T1 and T2 mapping, and biochemical markers: A longitudinal cardiac resonance imaging study during 2 years of follow-up, Sorin Giusca, Grigorios Korosoglou, Moritz Montenbruck, Blaž Geršak, Arne Kristian Schwarz, Sebastian Esch, Sebastian Kelle, Pia Wülfing, Susan Dent, Daniel Lenihan, and Henning Steen

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N-cadherin in osteolineage cells modulates stromal support of tumor growth, Francesca Fontana, Jingyu Xiang, Xinming Su, Eric Tycksen, Rachel Nassau, Gregory Fox, Giulia Leanza, Katherine Weilbaecher, and Roberto Civitelli

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Outcomes and risk factors associated with SARS-CoV-2 infection in a North American registry of patients with multiple sclerosis, Amber Salter, Robert J Fox, Scott D Newsome, June Halper, David K B Li, Pamela Kanellis, Kathleen Costello, Bruce Bebo, Kottil Rammohan, Gary R Cutter, and Anne H Cross

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Placental pathology in an unsuspected case of mucolipidosis type II with secondary hyperparathyroidism in a premature infant, Parith Wongkittichote, Garland Michael Upchurch, Louis P Dehner, Timothy Wood, and Jorge L Granadillo

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Randomized trial of the efficacy and safety of berotralstat (BCX7353) as an oral prophylactic therapy for hereditary angioedema: Results of APeX-2 through 48 weeks (part 2), H James Wedner and et al.

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Reliance on Cox10 and oxidative metabolism for antigen-specific NK cell expansion, Annelise Y Mah-Som, Molly P Keppel, Joshua M Tobin, Ana Kolicheski, Nermina Saucier, Veronika Sexl, Anthony R French, Julia A Wagner, Todd A Fehniger, and Megan A Cooper

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Report dose-to-medium in clinical trials where available; A consensus from the Global Harmonisation Group to maximize consistency, Stephen F Kry, Jeff Michalski, and et al.

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Restless legs syndrome shows increased silent postmortem cerebral microvascular disease with gliosis, Arthur S Walters, Paisit Paueksakon, Charles H Adler, Michael Moussouttas, Leonard B Weinstock, Karen Spruyt, and Kanika Bagai

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SARS-CoV-2 detection among international air travellers to Ghana during mandatory quarantine, Bright Adu, Joseph K H Bonney, John K Odoom, Evelyn Y A Bonney, Evangeline Obodai, Ivy A Asante, James Aboagye, Mildred A Adusei-Poku, Lawrence Lartey, Ernest K Asiedu, William K Ampofo, and George B Kyei

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Sleep drive reconfigures wake-promoting clock circuitry to regulate adaptive behavior, Markus K. Klose and Paul J. Shaw

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The Azithromycin to Prevent Wheezing following severe RSV bronchiolitis-II clinical trial: Rationale, study design, methods, and characteristics of study population, Mythili Srinivasan, Leonard B Bacharier, Charles W Goss, Yanjiao Zhou, Jonathan Boomer, Sarah Bram, Dana Burgdorf, Carey-Ann Burnham, Timothy Casper, Mario Castro, Andrea Coverstone, Matthew Haslam, Watcharoot Kanchongkittiphon, Cadence Kuklinski, Qinghua Lian, Kenneth Schechtman, Gregory A Storch, Kelly true, Meghan A Wallace, Huiqing Yin-DeClue, Elizabeth Ahrens, Jinli Wang, and Avraham Beigelman

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Transfer transcriptomic signatures for infectious diseases, Julia di Iulio, Istvan Bartha, Roberto Spreafico, Herbert W Virgin, and Amalio Telenti

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Safety and efficacy of umbilical cord-derived Wharton's jelly compared to hyaluronic acid and saline for knee osteoarthritis: Study protocol for a randomized, controlled, single-blind, multi-center trial, Ashim Gupta, Nicola Maffulli, Hugo C Rodriguez, Eric W Carson, Randa A Bascharon, Kristin Delfino, Howard J Levy, and Saadiq F El-Amin

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Hypergraph models of biological networks to identify genes critical to pathogenic viral response, Song Feng, Larissa B Thackray, Qing Tan, Michael S Diamond, and et al

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A cardiac rehabilitation program for breast cancer survivors: A feasibility study, Filadelfiya Zvinovski, Julie A Stephens, Bhuvaneswari Ramaswamy, Raquel E Reinbolt, Anne M Noonan, Jeffrey Bryan VanDeusen, Robert Wesolowski, Daniel G Stover, Nicole Olivia Williams, Sagar D Sardesai, Laxmi Mehta, Randi Foraker, Martha Gulati, Maryam Lustberg, and Allison M Quick

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A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection, Tania Lebratti, Ying Shiang Lim, Adjoa Cofie, Prabhakar Andhey, Xiaoping Jiang, Jason Scott, Maria Rita Fabbrizi, Ayşe Naz Ozantürk, Christine Pham, Regina Clemens, Maxim Artyomov, Mary Dinauer, and Haina Shin

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Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer's disease, Wei Qin, Aihong Zhou, Xiumei Zuo, Longfei Jia, Fangyu Li, Qi Wang, Ying Li, Yiping Wei, Hongmei Jin, Carlos Cruchaga, Bruno A Benitez, and Jianping Jia

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Spontaneous neural synchrony links intrinsic spinal sensory and motor networks during unconsciousness, Jacob Graves McPherson and Maria F. Bandres

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Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala, Vijay K. Samineni, Jose G. Grajales-Reyes, Gary E. Grajales-Reyes, Eric Tycksen, Bryan A. Copits, Christian Pedersen, Edem S. Ankudey, Julian N. Sackey, Sienna B. Sewell, Michael R. Bruchas, and Robert W. Gereau

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Cell-autonomous retinoic acid receptor signaling has stage-specific effects on mouse enteric nervous system, Tao Gao, Elizabeth C. Wright-Jin, Rajarshi Sengupta, Jessica B. Anderson, and Robert O Heuckeroth

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Novel autosegmentation spatial similarity metrics capture the time required to correct segmentations better than traditional metrics in a thoracic cavity segmentation workflow, Kendall J Kiser, Arko Barman, Sonja Stieb, Clifton D Fuller, and Luca Giancardo

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Common DNA methylation dynamics in endometriod adenocarcinoma and glioblastoma suggest universal epigenomic alterations in tumorigenesis, Jennifer A Karlow, Benpeng Miao, Xiaoyun Xing, Ting Wang, and Bo Zhang

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Semi-supervised peak calling with SPAN and JBR genome browser, Oleg Shpynov, Aleksei Dievskii, Roman Chernyatchik, Petr Tsurinov, and Maxim N Artyomov

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Electronic clinical decision support for children with minor head trauma and intracranial injuries: A sociotechnical analysis, Jacob K Greenberg, Ayodamola Otun, Azzah Nasraddin, Ross C Brownson, Nathan Kuppermann, David D Limbrick, Po-Yin Yen, and Randi E Foraker

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Phenotypic and genomic profiling of Staphylococcus argenteus in Canada and the United States and recommendations for clinical result reporting, AliReza Eshaghi, Carl Bommersbach, Sandra Zittermann, C A Burnham, Robin Patel, Audrey N Schuetz, Samir N Patel, and Julianne V Kus

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Experience with liposomal amphotericin B in outpatient parenteral antimicrobial therapy, Yvonne J Burnett, Andrej Spec, Mohamed M Ahmed, William G Powderly, and Yasir Hamad

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One-year urinary and sexual outcome trajectories among prostate cancer patients treated by radical prostatectomy: A prospective study, Lin Yang, Jung Ae Lee, Emily Heer, Claire Pernar, Graham A Colditz, Ratna Pakpahan, Kellie R Imm, Eric H Kim, Robert L Grubb 3rd, Kathleen Y Wolin, Adam S Kibel, and Siobhan Sutcliffe

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Tofacitinib, an oral Janus kinase inhibitor: Analysis of malignancy (excluding nonmelanoma skin cancer) events across the ulcerative colitis clinical program, Gary R Lichtenstein, Gerhard Rogler, Matthew A Ciorba, Chinyu Su, Gary Chan, Ronald D Pedersen, Nervin Lawendy, Daniel Quirk, Chudy I Nduaka, Andrew J Thorpe, and Julian Panés

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Value CMR: Towards a comprehensive, rapid, cost-effective cardiovascular magnetic resonance imaging, El-Sayed H Ibrahim, Luba Frank, Dhiraj Baruah, V Emre Arpinar, Andrew S Nencka, Kevin M Koch, L Tugan Muftuler, Orhan Unal, Jadranka Stojanovska, Jason C Rubenstein, Sherry-Ann Brown, John Charlson, Elizabeth M Gore, and Carmen Bergom

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A genetic screen for regulators of muscle morphogenesis in Drosophila, Tiffany Ou, Gary Huang, Beth Wilson, Paul Gontarz, James B Skeath, and Aaron N Johnson

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Stroma-targeting strategies in pancreatic cancer: Past lessons, challenges and prospects, Faran Polani, Patrick M Grierson, and Kian-Huat Lim

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Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease, Alexa Pichet Binette, Tammie Benzinger, John Morris, Randall Bateman, and et al

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Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection, Lina Ma, Sanjaya K. Sahu, Marlene Cano, Vasanthan Kuppuswamy, Jamal Bajwa, Ja’Nia McPhatter, Tingting Lei, Aaron Day, Daniel Reynolds, Xiaobo Wu, Rebecca Schriefer, Adriana M. Rauseo, Charles W. Goss, Jane A. O’Halloran, Rachel M. Presti, Alfred H. Kim, Andrew E. Gelman, Philip A. Mudd, John P. Atkinson, Hrishikesh S. Kulkarni, and et al.

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Presepsin as a diagnostic and prognostic biomarker in sepsis, Dimitrios Velissaris, Nicholas Zareifopoulos, Vasileios Karamouzos, Evangelos Karanikolas, Charalampos Pierrakos, Ioanna Koniari, and Menelaos Karanikolas

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Cancer-associated mutations reveal a novel role for EpCAM as an inhibitor of cathepsin-L and tumor cell invasion, Narendra V Sankpal, Taylor C Brown, Timothy P Fleming, John M Herndon, Anusha A Amaravati, Allison N Loynd, and William E Gillanders

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Gene expression dynamics underlying cell fate emergence in 2D micropatterned human embryonic stem cell gastruloids, Kyaw Thu Minn, Sabine Dietmann, Sarah E Waye, Samantha A Morris, and Lilianna Solnica-Krezel

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Manure microbial communities and resistance profiles reconfigure after transition to manure pits and differ from those in fertilized field soil, Kimberley V Sukhum, Rhiannon C Vargas, Manish Boolchandani, Alaric W D'Souza, Sanket Patel, Akhil Kesaraju, Gretchen Walljasper, Harshad Hegde, Zhan Ye, Robert K Valenzuela, Paul Gunderson, Casper Bendixsen, Gautam Dantas, and Sanjay K Shukla

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Transferrable protection by gut microbes against STING-associated lung disease, Derek J Platt, Dylan Lawrence, Rachel Rodgers, Lawrence Schriefer, Wei Qian, Cathrine A Miner, Amber M Menos, Elizabeth A Kennedy, Stefan T Peterson, W Alexander Stinson, Megan T Baldridge, and Jonathan J Miner

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Implementation and sustainability factors of two early-stage breast cancer conversation aids in diverse practices, Danielle Schubbe, Mary C Politi, Julie Margenthaler, Courtney Goodwin, and et al

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Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations, Kari T. Chambers, Michael A. Cooper, Alison R. Swearingen, Rita T. Brookheart, George G. Schweitzer, Carla J. Weinheimer, Attila Kovacs, Timothy R. Koves, Deborah M. Muoio, Kyle S. McCommis, and Brian N. Finck

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Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria, Akansha Mishra, Chen Kang, Rajan Sah, and et al.

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Recovery of consciousness and cognition after general anesthesia in humans, George A. Mashour, Ben J.A. Palanca, Wei Wang, Nan Lin, Maxwell Muench, Hannah Maybrier, Michael S. Avidan, and et al

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Long-term mortality after Histoplasma infection in people with HIV, Joseph Cherabie, Patrick Mazi, Adriana M Rauseo, Chapelle Ayres, Lindsey Larson, Sasinuch Rutjanawech, Jane O'Halloran, Rachel Presti, William G Powderly, and Andrej Spec

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Model organisms contribute to diagnosis and discovery in the Undiagnosed Diseases Network: Current state and a future vision, Dustin Baldridge, Michael F Wangler, Angela N Bowman, Shinya Yamamoto, Undiagnosed Diseases Network, Tim Schedl, Stephen C Pak, John H Postlethwait, Jimann Shin, Lilianna Solnica-Krezel, Hugo J Bellen, and Monte Westerfield

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Neurological diseases and COVID-19: Prospective analyses using the UK Biobank, Nicola Veronese, Lee Smith, Mario Barbagallo, Gianluigi Giannelli, Maria Gabriella Caruso, Anna Maria Cisternino, Maria Notarnicola, Chao Cao, Thomas Waldhoer, and Lin Yang

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Waning efficacy in a long-term AAV-mediated gene therapy study in the murine model of Krabbe disease, Gregory J Heller, Michael S Marshall, Yazan Issa, Jeffrey N Marshall, Duc Nguyen, Emily Rue, Koralege C Pathmasiri, Miriam S Domowicz, Richard B van Breemen, Leon M Tai, Stephanie M Cologna, Stephen J Crocker, Maria I Givogri, Mark S Sands, and Ernesto R Bongarzone

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Genetic causes of cardiomyopathy in children: First results from the Pediatric Cardiomyopathy Genes Study, Stephanie M Ware, Charles E Canter, and et al

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Multi-omic analysis elucidates the genetic basis of hydrocephalus, Andrew T Hale, Lisa Bastarache, Diego M Morales, John C Wellons III, David D Limbrick Jr., and Eric R Gamazon

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A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: Findings from a multi cohort validity analysis, Tim West, Kristopher M Kirmess, Matthew R Meyer, Mary S Holubasch, Stephanie S Knapik, Yan Hu, John H Contois, Erin N Jackson, Scott E Harpstrite, Randall J Bateman, David M Holtzman, Philip B Verghese, Ilana Fogelman, Joel B Braunstein, and Kevin E Yarasheski

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Ancestry specific associations of a genetic risk score, dietary patterns and metabolic syndrome: A longitudinal ARIC study, Dale S Hardy, Susan B Racette, Jane T Garvin, Hirut T Gebrekristos, and Tesfaye B Mersha

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A neuroskeletal atlas: Spatial mapping and contextualization of axon subtypes innervating the long bones of C3H and B6 mice, Madelyn R Lorenz, Jennifer M Brazill, Alec T Beeve, Ivana Shen, and Erica L Scheller

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A phase 2, double-blind, randomized, dose-ranging trial of reldesemtiv in patients with ALS, Jeremy M. Shefner, Timothy M. Miller, and et al

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Association of physician group practice participation in bundled payments with patient selection, costs, and outcomes for joint replacement, Karen E Joynt Maddox, E John Orav, Jie Zheng, and Arnold M Epstein

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A systematic review of higher-risk myelodysplastic syndromes clinical trials to determine the benchmark of azacitidine and explore alternative endpoints for overall survival, Jacqueline S Garcia, Ronan T Swords, Gail J Roboz, Meagan A Jacoby, Guillermo Garcia-Manero, Wan-Jen Hong, Xiaoqing Yang, Ying Zhou, Uwe Platzbecker, David P Steensma, Johannes E Wolff, and Pierre Fenaux

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Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease, Jacob M Basak, Aura Ferreiro, Lucy S Cohen, Patrick W Sheehan, Collin J Nadarajah, Michael F Kanan, Kimberley V Sukhum, Gautam Dantas, and Erik S Musiek

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Crohn's disease-associated ATG16L1 T300A genotype is associated with improved survival in gastric cancer, Changqing Ma, Chad E Storer, Uma Chandran, William A LaFramboise, Patricia Petrosko, Madison Frank, Douglas J Hartman, Liron Pantanowitz, Talin Haritunians, Richard D Head, and Ta-Chiang Liu

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Effects of community-based antiretroviral therapy initiation models on HIV treatment outcomes: A systematic review and meta-analysis, Ingrid Eshun-Wilson, Ajibola A. Awotiwon, Ashley Germann, Sophia A. Amankwaa, Nathan Ford, Sheree Schwartz, Stefan Baral, and Elvin H. Geng

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Endoscopic retrieval of a proximally migrated biliary stent using extracorporeal shockwave lithotripsy, electrohydraulic lithotripsy, and cholangioscopy with minisnare, Michael J Weaver and Vladimir M Kushnir

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Epigenomic regulation of human T-cell leukemia virus by chromatin-insulator CTCF, Xiaogang Cheng, Ancy Joseph, Victor Castro, Alice Chen-Liaw, Zachary Skidmore, Takaharu Ueno, Jun-Ichi Fujisawa, Daniel A. Rauch, Grant A. Challen, Michael P. Martinez, Patrick Green, Malachi Griffith, Jacqueline E. Payton, John R. Edwards, and Lee Ratner

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Gardnerella vaginalis promotes group B Streptococcus vaginal colonization, enabling ascending uteroplacental infection in pregnant mice, Nicole M Gilbert, Lynne R Foster, Bin Cao, Yin Yin, Indira U Mysorekar, and Amanda L Lewis

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Long-term outcomes of operatively treated medial epicondyle fractures in pediatric and adolescent patients, Ronak M Patel, Yash Tarkunde, Lindley B Wall, Gregory Schimizzi, and Charles A Goldfarb

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Obese endometrial cancer survivors' perceptions of weight loss strategies and characteristics that may influence participation in behavioral interventions, Elise M Wilson, Abigail S Zamorano, Jingxia Liu, David Morris, Andrea Leon, Lindsay M Kuroki, Premal H Thaker, Carolyn K McCourt, Katherine C Fuh, Matthew A Powell, David G Mutch, Graham A Colditz, and Andrea R Hagemann

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Patient-reported outcomes from a randomized, active-controlled, open-label, phase 3 trial of burosumab versus conventional therapy in children with X-linked hypophosphatemia, Raja Padidela, Michael P Whyte, and et al.

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Placental sampling for understanding viral infections - A simplified protocol for the COVID-19 pandemic, Guilherme de Moraes Nobrega, José Paulo Siqueira Guida, Rodolfo Rosa Japecanga, Arthur Antolini-Tavares, Indira Mysorekar, and Maria Laura Costa

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Polygenic contributions to alcohol use and alcohol use disorders across population-based and clinically ascertained samples, Emma C Johnson, Kathleen K Bucholz, Arpana Agrawal, and et al

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Postsurgical presentation of Zollinger-Ellison syndrome after resection of endometrioid neuroendocrine tumor, Aymen Almuhaidb and Nicholas O Davidson

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Quantitative signal properties from standardized MRIs correlate with multiple sclerosis disability, Matthew R Brier, Abraham Z Snyder, Aaron Tanenbaum, Richard A Rudick, Elizabeth Fisher, Stephen Jones, Joshua S Shimony, Anne H Cross, Tammie L S Benzinger, and Robert T Naismith