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Submissions from 2021

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The Dark Kinase Knowledgebase: An online compendium of knowledge and experimental results of understudied kinases, Matthew E. Berginski, Nienke Moret, Changchang Liu, Dennis Goldfarb, Peter K. Sorger, and Shawn M. Gomez

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Relationship between clinicopathologic factors and FDG avidity in radioiodine-negative recurrent or metastatic differentiated thyroid carcinoma, Le Ngoc Ha, Amir Iravani, Nguyen Thi Nhung, Ngo Thi Minh Hanh, Febby Hutomo, and Mai Hong Son

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Application of systems dynamics and group model building to identify barriers and facilitators to acute care delivery in a resource limited setting, Fiona Muttalib, Ellis Ballard, Josephine Langton, Sara Malone, Yudy Fonseca, Andreas Hansmann, Kenneth Remy, Peter Hovmand, and Allan Doctor

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Small molecule SARM1 inhibitors recapitulate the SARM1 -/- phenotype and allow recovery of a metastable pool of axons fated to degenerate, Robert O Hughes, Todd Bosanac, Xianrong Mao, Thomas M Engber, Aaron DiAntonio, Jeffrey Milbrandt, Rajesh Devraj, and Raul Krauss

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Function of mammalian M-cones depends on the level of CRALBP in Müller cells, Alexander V. Kolesnikov, Philip D. Kiser, Krzysztof Palczewski, and Vladimir J. Kefalov

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4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor, Ofer Moldavski, Peter-James H. Zushin, Charles A. Berdan, Robert J. Van Eijkeren, Xuntian Jiang, Mingxing Qian, Daniel S. Ory, Douglas F. Covey, Daniel K. Nomura, Andreas Stahl, Ethan J. Weiss, and Roberto Zoncu

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AAPM medical physics practice guideline 3.b.: Levels of supervision for medical physicists in clinical training, Douglas Pfeiffer, Hania Al-Hallaq, Per Halvorsen, Kristi Hendrickson, Zheng Feng Lu, Melissa Carol Martin, Beth Schueler, Jillian Shuman, and Jacqueline E Zoberi

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Ablative five-fraction stereotactic body radiation therapy for inoperable pancreatic cancer using online MR-guided adaptation, Comron Hassanzadeh, Soumon Rudra, Ani Bommireddy, William G Hawkins, Andrea Wang-Gillam, Ryan C Fields, Bin Cai, Justin Park, Olga Green, Michael Roach, Lauren Henke, and Hyun Kim

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A bone-specific adipogenesis pathway in fat-free mice defines key origins and adaptations of bone marrow adipocytes with age and disease, Xiao Zhang, Hero Robles, Kristann L. Magee, Madelyn R. Lorenz, Zhaohua Wang, Charles A. Harris, Clarissa S. Craft, and Erica L. Scheller

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Academic performance of children with sickle cell disease in the United States: A meta-analysis, Andrew M Heitzer, Latacha Hamilton, Claire Stafford, Jeffrey Gossett, Lara Ouellette, Ana Trpchevska, Allison A King, Guolian Kang, and Jane S Hankins

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A canker barking at the wrong knee: Thyronectria austroamericana septic arthritis, Sasinuch Rutjanawech, Carlos Mejia-Chew, Chapelle Ayres, and Andrej Spec

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Acanthamoeba keratitis, pathology, diagnosis and treatment, Nicholas Fanselow, Nadia Sirajuddin, Xiao-Tang Yin, Andrew J W Huang, and Patrick M Stuart

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Acaricidal activity of Foeniculum vulgare against Rhipicephalus annulatus is mainly dependent on its constituent from trans-anethone, Shawky M. Aboelhadid, Waleed M. Arafa, Abdel-Azeem S. Abdel-Baki, Atalay Sokmen, Saleh Al-Quraishy, Ahmed O. Hassan, and Asmaa A. Kamel

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A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors, Pierre Mattar, Christine Jolicoeur, Thanh Dang, Sujay Shah, Brian S. Clark, and Michel Cayouette

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Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease, Julie Gonneaud, Brian A. Gordon, Carlos Cruchaga, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Susan Brandon, Virginia Buckles, Tamara Donahue, Anne Fagan, Gigi Flynn, Erin Franklin, Cortaiga Gant, Julia Gray, Alexander Groves, Jason Hassenstab, Laura Hoechst-Swisher, David Holtzman, Russ Hornbeck, Gina Jerome, Celeste Karch, Denise Maue-Dreyfus, Eric McDade, Joanne Norton, Richard Perrin, Marc Raichle, Wendy Sigurdson, Peter Wang, Chengjie Xiong, Xiong Xu, Nigel J. Cairns, Erin Householder, Lisa Taylor Reinwald, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, and et al

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Acceleration of small intestine development and remodeling of the microbiome following hyaluronan 35 KDa treatment in neonatal mice, Hala Chaaban, Kathryn Burge, Jeffrey Eckert, MaJoi Trammell, David Dyer, Ravi S Keshari, Robert Silasi, Girija Regmi, Cristina Lupu, Misty Good, Steven J McElroy, and Florea Lupu

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Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice, Benjamin Caballero, Celeste M. Karch, and et al.

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Achieving a diverse, equitable, and inclusive environment for the Black orthopaedic surgeon: Part 1: Barriers to successful recruitment of Black applicants, Gabriella E Ode, Letitia Bradford, William A Ross, Eric W Carson, and Jaysson T Brooks

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A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution, Wesley C. Warren, Chad Tomlinson, Milinn Kremitzki, Tina Graves-Lindsay, and et al.

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Acitretin mitigates uroporphyrin‑induced bone defects in congenital erythropoietic porphyria models, Juliana Bragazzi Cunha, Jared S. Elenbaas, Dhiman Maitra, Ning Kuo, Rodrigo Azuero-Dajud, Allison C. Ferguson, Megan S. Griffin, Stephen I. Lentz, Jordan A. Shavit, and M. Bishr Omary

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A clinician's guide for navigating the world of attention deficit hyperactivity disorder medications, Gregory W Mattingly and Joel Young

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A comparison of prediction approaches for identifying prodromal Parkinson disease, Mark N. Warden, Susan Searles Nielsen, Alejandra Camacho-Soto, Roman Garnett, and Brad A. Racette

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A comprehensive review of tic disorders in children, Keisuke Ueda and Kevin J Black

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A cross-sectional comparison of physical activity during COVID-19 in a sample of rural and non-rural participants in the US, Alan M Beck, Amanda S Gilbert, Dixie D Duncan, and Eric M Wiedenman

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Activated microglia mitigate Aβ-associated tau seeding and spreading, Maud Gratuze, Yun Chen, Samira Parhizkar, Nimansha Jain, Michael R. Strickland, Javier Remolina Serrano, Marco Colonna, Jason D. Ulrich, and David M. Holtzman

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Acupuncture and oxytocinergic system: The promising treatment for autism, Tangfeng Su and Lei Pei

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Acute acalculous cholecystitis-associated bacteremia has worse outcome, Javier E. Rincon, Rohit K. Rasane, Jose A. Aldana, Christina X. Zhang, Ricardo A. Fonseca, Qiao Zhang, Kelly M. Bochicchio, Obeid N. Ilahi, and Grant V. Bochicchio

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Acute symptoms of mild to moderate COVID-19 are highly heterogeneous across individuals and over time, Thomas L. Rodebaugh, Madelyn R. Frumkin, Angela M. Reiersen, Eric J. Lenze, Michael S. Avidan, J. Philip Miller, Jay F. Piccirillo, Charles F. Zorumski, and Caline Mattar

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A decade in review after Idiopathic Scoliosis was first called a complex trait-A tribute to the late Dr. Yves Cotrel for his support in studies of etiology of scoliosis, Nelson L S Tang, Matthew B Dobbs, Christina A Gurnett, Yong Qiu, T P Lam, Jack C Y Cheng, and Nancy Hadley-Miller

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Adherence of internet-based cancer risk assessment tools to best practices in risk communication: Content analysis, Erika A Waters, Jeremy L Foust, Laura D Scherer, Amy McQueen, and Jennifer M Taber

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Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox, Biswajit Khatua, Bara El-Kurdi, Krutika Patel, Christopher Rood, Pawan Noel, Michael Crowell, Jordan R Yaron, Sergiy Kostenko, Andre Guerra, Douglas O Faigel, Mark Lowe, and Vijay P Singh

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Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis, Yi Zhu, Gordon I. Smith, Samuel Klein, and et al

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Adolescent animal product intake in relation to later prostate cancer risk and mortality in the NIH-AARP Diet and Health Study, Tuo Lan, Yikyung Park, Graham A Colditz, Jingxia Liu, Rashmi Sinha, Molin Wang, Kana Wu, Edward Giovannucci, and Siobhan Sutcliffe

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Adolescent idiopathic scoliosis treated by posterior spinal segmental instrumented fusion : When is fusion to L3 stable?, Seung-Jae Hyun, Lawrence G. Lenke, Yongjung Kim, Keith H. Bridwell, Meghan Cerpa, and Kathy M. Blanke

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A domestic cat whole exome sequencing resource for trait discovery, Alana R. Rodney, Rueben M. Buckley, Robert S. Fulton, Catrina Fronick, Todd Richmond, Christopher R. Helps, Peter Pantke, Dianne J. Trent, Karen M. Vernau, John S. Munday, Andrew C. Lewin, Rondo Middleton, Leslie A. Lyons, and Wesley C. Warren

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Adult patient preferences for long-acting ADHD treatments: A discrete choice experiment, M Janelle Cambron-Mellott, Jaromir Mikl, Joana E Matos, Jennifer G Erensen, Kathleen Beusterien, Marc J Cataldo, Bernadette Hallissey, and Gregory W Mattingly

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Advances in genetic and molecular understanding of Alzheimer's disease, Laura Ibanez, Carlos Cruchaga, and Maria Victoria Fernández

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Advantages of 18F-FDG PET/CT imaging over modified Duke criteria and clinical presumption in patients with challenging suspicion of infective endocarditis, Valentin Pretet, Cyrille Blondet, Yvon Ruch, Matias Martinez, Soraya El Ghannudi, Olivier Morel, Yves Hansmann, Thomas H Schindler, and Alessio Imperiale

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African Americans have differences in CSF soluble TREM2 and associated genetic variants, Suzanne E. Schindler, Carlos Cruchaga, Amulya Jospeh, Lena McCue, Fabiana H.G. Farias, Consuelo H. Wilkins, Yuetiva Deming, Rachel L. Henson, Robert J. Mikesell, Laura Piccio, Jorge J. Llibre-Guerra, Krista L. Moulder, Anne M. Fagan, Beau M. Ances, Tammie L.S. Benzinger, Chengjie Xiong, David M. Holtzman, and John C. Morris

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A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor, Akira Inoue, Laura J Janke, Brian L Gudenas, Hongjian Jin, Yiping Fan, Joshua Paré, Michael R Clay, Paul A Northcott, Angela C Hirbe, and Xinwei Cao

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A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery, Yun-Rak Choi, Kelsey H Collins, Luke E Springer, Lara Pferdehirt, Alison K Ross, Chia-Lung Wu, Franklin T Moutos, Natalia S Harasymowicz, Jonathan M Brunger, Christine T N Pham, and Farshid Guilak

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Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology, Sandro Da Mesquita, Jasmin Herz, Morgan Wall, Taitea Dykstra, Kalil Alves de Lima, Geoffrey T Norris, Nisha Dabhi, Tatiana Kennedy, Wendy Baker, and Jonathan Kipnis

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A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis, Lisa K. McLellan, Michael R. McAllaster, Arthur S. Kim, Ľubomíra Tóthová, Patrick D. Olson, Jerome S. Pinkner, Allyssa L. Daugherty, Teri N. Hreha, James W. Janetka, Daved H. Fremont, Scott J. Hultgren, Herbert W. Virgin, and David A. Hunstad

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Air pollution particulate matter amplifies white matter vascular pathology and demyelination caused by hypoperfusion, Mikko T Huuskonen, Qinghai Liu, Krista Lamorie-Foote, Kristina Shkirkova, Michelle Connor, Arati Patel, Axel Montagne, Hans Baertsch, Constantinos Sioutas, Todd E Morgan, Caleb E Finch, Berislav V Zlokovic, and William J Mack

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A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis, David Pradella, William Vermi, and et al

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All epidural needle bevels are not the same, Amber C. Benhardt and Bhavani Shankar Kodali

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Allosteric effects of SSB C-terminal tail on assembly of E. coli RecOR proteins, Min Kyung Shinn, Alexander G. Kozlov, and Timothy M. Lohman

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Altered mapping of sound frequency to cochlear place in ears with endolymphatic hydrops provide insight into the pitch anomaly of diplacusis, J.J. Guinan Jr., S.M. Lefler, C.A. Buchman, S.S. Goodman, and J.T. Lichtenhan

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A machine learning approach for the factorization of psychometric data with application to the Delis Kaplan Executive Function System, J.A. Camilleri, S.B. Eickhoff, S. Weis, J. Chen, J. Amunts, A. Sotiras, and S. Genon

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American Society of Hematology 2021 guidelines for sickle cell disease: Stem cell transplantation, Julie Kanter, Robert I. Liem, Françoise Bernaudin, Javier Bolaños-Meade, Courtney D. Fitzhugh, Jane S. Hankins, M. Hassan Murad, Julie A. Panepinto, Damiano Rondelli, Shalini Shenoy, John Wagner, Mark C. Walters, Teonna Woolford, Joerg J. Meerpohl, and John Tisdale

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American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19, Adam Cuker, Kristen M. Sanfilippo, and et al.

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A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure, Raymond J. Langley, Patrick Luckett, and et al.

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A microfluidic-based filtration system to enrich for bone marrow disseminated tumor cells from breast cancer patients, Sreeraj G. Pillai, Chidananda M. Siddappa, Cynthia Ma, Jackie Snider, Madhurima Kaushal, Mark A. Watson, and Rebecca Aft

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A modified Delphi approach to develop a trial protocol for antibiotic de-escalation in patients with suspected sepsis, Michael E Yarrington, Rebekah W Moehring, Michael Z David, Keith W Hamilton, Michael Klompas, Chanu Rhee, Kevin Hsueh, Elizabeth Dodds Ashley, Ronda L Sinkowitz-Cochran, Matthew Ryan, Deverick J Anderson, and DETOURS Expert Panel of the CDC Prevention Epicenters Program

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A mouse model displays host and bacterial strain differences in Aerococcus urinae urinary tract infection, Nicole M Gilbert, Brian Choi, Jingjie Du, Christina Collins, Amanda L Lewis, Catherine Putonti, and Alan J Wolfe

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A multi-step nucleation process determines the kinetics of prion-like domain phase separation, Erik W. Martin, Tyler S. Harmon, Jesse B. Hopkins, Srinivas Chakravarthy, J. Jeremías Incicco, Peter Schuck, Andrea Soranno, and Tanja Mittag

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Anabolic resistance of muscle protein turnover comes in various shapes and sizes, Kevin J M Paulussen, Colleen F McKenna, Joseph W Beals, Kenneth R Wilund, Amadeo F Salvador, and Nicholas A Burd

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An absence of equipoise: Examining surgeons' decision talk during encounters with women considering breast cancer surgery, Mary C. Politi, Catherine H. Saunders, Victoria F. Grabinski, Renata W. Yen, Amy E. Cyr, Marie-Anne Durand, and Glyn Elwyn

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Analysis of amyloid-like secondary structure in the Cryab-R120G knock-in mouse model of hereditary cataracts by two-dimensional infrared spectroscopy, Ariel M. Alperstein, Kathleen S. Molnar, Sidney S. Dicke, Kieran M. Farrell, Leah N. Makley, Martin T. Zanni, and Usha P Andley

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Analysis of delayed surgical treatment and oncologic outcomes in clinical stage I non-small cell lung cancer, Brendan T. Heiden, Daniel B. Eaton, Kathryn E. Engelhardt, Su-Hsin Chang, Yan Yan, Mayank R. Patel, Daniel Kreisel, Ruben G. Nava, Bryan F. Meyers, Benjamin D. Kozower, and Varun Puri

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Analysis of post-transplant lymphoproliferative disorder (PTLD) outcomes with Epstein-Barr virus (EBV) assessments-a single tertiary referral center experience and review of literature, Eric Lau, Lawrence Liu, and et al

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Analysis of ureteral diameter and peristalsis in response to irrigant fluid temperature changes in an in vivo porcine model, Roshan M. Patel, Pengbo Jiang, Rajiv Karani, Tarik Phillips, Raphael B. Arada, Lillian Xie, Hyder Said, Shlomi Tapiero, Jaime Landman, Ted Farzaneh, Ramakrishna Venkatesh, and Ralph V. Clayman

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A nationwide virtual research education program for medical students in Pakistan: Methodological framework, feasibility testing, and outcomes, Ali Aahil Noorali, Maha Inam, Hamna Shahbaz, Hareem Rauf, Faiqa Binte Aamir, Farah Khalid, Saadia Abbas, Abdullah Saeed, Muhammad Daniyal Musharraf, Asma Altaf Hussain Merchant, Babar S Hasan, Muneera A Rasheed, Fyezah Jehan, Muhammad Tariq, and Adil Hussain Haider

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An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei, Giulia Bandini, Sebastian Damerow, Maria Lucia Sempaio Guther, Hongjie Guo, Angela Mehlert, Jose Carlos Paredes Franco, Stephen Beverley, and Michael A.J. Ferguson

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Anesthesia for GI endoscopy in the era of COVID-19, Basavana Goudra and Preet Mohinder Singh

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Anesthesia for thoracic surgery in infants and children, Teresa M. Murray-Torres, Peter D. Winch, Aymen N. Naguib, and Joseph D. Tobias

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An integrated approach to identify new anti-filarial leads to treat river blindness, a neglected tropical disease, Rahul Tyagi, Christina A Bulman, Fidelis Cho-Ngwa, Chelsea Fischer, Chris Marcellino, Michelle R Arkin, James H McKerrow, Case W McNamara, Matthew Mahoney, Nancy Tricoche, Shabnam Jawahar, James W Janetka, Sara Lustigman, Judy Sakanari, and Makedonka Mitreva

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An international virtual hackathon to build tools for the analysis of structural variants within species ranging from coronaviruses to vertebrates [version 2; peer review: 1 approved, 3 approved with reservations], Ann M. McCartney, Daniel Paiva Agustinho, and et al

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An open label, block randomized, community study of the safety and efficacy of co-administered ivermectin, diethylcarbamazine plus albendazole vs. diethylcarbamazine plus albendazole for lymphatic filariasis in India, Purushothaman Jambulingam, Vijesh Sreedhar Kuttiatt, Kaliannagounder Krishnamoorthy, Swaminathan Subramanian, Adinarayanan Srividya, Hari Kishan K. Raju, Manju Rahi, Roopali K. Somani, Mallanna K. Suryaprakash, Gangeshwar P. Dwivedi, and Gary J Weil

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An open label, randomized clinical trial to compare the tolerability and efficacy of ivermectin plus diethylcarbamazine and albendazole vs. diethylcarbamazine plus albendazole for treatment of brugian filariasis in Indonesia, Taniawati Supali, Yenny Djuardi, Michael Christian, Elisa Iskandar, Rahmat Alfian, Roospita Maylasari, Yossi Destani, Adriani Lomiga, Dominikus Minggu, Daphne Lew, Joshua Bogus, Gary J Weil, and Peter U. Fischer

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A novel precision approach to overcome the "addiction pandemic" by incorporating genetic addiction risk severity (GARS) and dopamine homeostasis restoration, Kenneth Blum, Shan Kazmi, Edward J Modestino, Bill William Downs, Debasis Bagchi, David Baron, Thomas McLaughlin, Richard Green, Rehan Jalali, Panayotis K Thanos, Igor Elman, Rajendra D Badgaiyan, Abdalla Bowirrat, and Mark S Gold

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Antibiotic-driven intestinal dysbiosis in pediatric short bowel syndrome is associated with persistently altered microbiome functions and gut-derived bloodstream infections, Robert Thänert, Anna Thänert, Jocelyn Ou, Adam Bajinting, Carey-Ann D Burnham, Holly J Engelstad, Maria E Tecos, I Malick Ndao, Carla Hall-Moore, Colleen Rouggly-Nickless, Mike A Carl, Deborah C Rubin, Nicholas O Davidson, Phillip I Tarr, Barbara B Warner, Gautam Dantas, and Brad W Warner

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Antidiabetic DPP-4 inhibitors reprogram tumor microenvironment that facilitates murine breast cancer metastasis through interaction with cancer cells via a ROS-NF-кB-NLRP3 axis, Rui Li, Xin Zeng, Meihua Yang, Jinmei Feng, Xiaohui Xu, Liming Bao, Tingbo Ye, Xin Wang, Bingqian Xue, and Yi Huang

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Antigen presenting cells link the female genital tract microbiome to mucosal inflammation, with hormonal contraception as an additional modulator of inflammatory signatures, Elizabeth H Byrne, Barry L Hykes, Scott A Handley, and et al

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Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel, William R. Arnold, Lauren N. Carnevale, Zili Xie, Javier L. Baylon, Emad Tajkhorshid, Hongzhen Hu, and Aditi Das

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Apathy, cognitive impairment, and social support contribute to participation in cognitively demanding activities poststroke, Amy Ho, Marjorie L. Nicholas, Chaitali Dagli, and Lisa Tabor Connor

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A phase 2 study of isatuximab monotherapy in patients with multiple myeloma who are refractory to daratumumab, Joseph Mikhael, Ravi Vij, and et al.

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A phase II study of laser interstitial thermal therapy combined with doxorubicin in patients with recurrent glioblastoma, Omar H Butt, Alice Y Zhou, Jiayi Huang, William A Leidig, Alice E Silberstein, Milan G Chheda, Tanner M Johanns, George Ansstas, Jingxia Liu, Grayson Talcott, Ruth Nakiwala, Joshua S Shimony, Albert H Kim, Eric C Leuthardt, Jian L Campian, and et al.

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A pilot study examining the prognostic utility of tumor shrinkage on cone-beam computed tomography (CBCT) for stage III locally advanced non-small cell lung cancer patients treated with definitive chemoradiation, Kylie H Kang, Jimmy T Efird, Tarun K Podder, Yuxia Zhang, Afshin Dowlati, Mitchell Machtay, Charulata Jindal, and Tithi Biswas

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A pilot study of 3D tissue‑engineered bone marrow culture as a tool to predict patient response to therapy in multiple myeloma, Kinan Alhallak, Amanda Jeske, Pilar de la Puente, Jennifer Sun, Mark Fiala, Feda Azab, Barbara Muz, Ilyas Sahin, Ravi Vij, John F. DiPersio, and Abdel Kareem Azab

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Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer, Valerie Blanc, Jesse D Riordan, Saeed Soleymanjahi, Joseph H Nadeau, ILKe Nalbantoglu, Yan Xie, Elizabeth A Molitor, Blair B Madison, Elizabeth M Brunt, Jason C Mills, Deborah C Rubin, Irene O Ng, Yeonjung Ha, Lewis R Roberts, and Nicholas O Davidson

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APOBEC1 mediated C-to-U RNA editing: Target sequence and trans-acting factor contribution to 177 RNA editing events in 119 murine transcripts in-vivo, Saeed Soleymanjahi, Valerie Blanc, and Nicholas Davidson

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Application of a time-series deep learning model to predict cardiac dysrhythmias in electronic health records, Aixia Guo, Sakima Smith, Yosef M. Khan, James R. Langabeer II, and Randi E. Foraker

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Application of electrical stimulation for peripheral nerve regeneration: Stimulation parameters and future horizons, Saad Javeed, Amir H. Faraji, Christopher Dy, Wilson Z. Ray, and Matthew R. MacEwan

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Application programming interface guided QA plan generation and analysis automation, Matthew C Schmidt, Caleb A Raman, Yu Wu, Mahmoud M Yaqoub, Yao Hao, Rebecca Nichole Mahon, Matthew J Riblett, Nels C Knutson, Erno Sajo, Piotr Zygmanski, Marian Jandel, Francisco J Reynoso, and Baozhou Sun

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Applications of iPSC-derived beta cells from patients with diabetes, Kristina G. Maxwell and Jeffrey R. Millman

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Approaches for ending ineffective programs: Strategies from state public health practitioners, Emily Rodriguez Weno, Peg Allen, Stephanie Mazzucca, Louise Farah Saliba, Margaret Padek, Sarah Moreland-Russell, and Ross C Brownson

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A priori activation of apoptosis pathways of tumor (AAAPT) technology: Development of targeted apoptosis initiators for cancer treatment, Raghu S. Pandurangi, Marco Tomasetti, Sekar T. Verapazham, Ramasamy Paulmurugan, Cynthia Ma, Sandeep Rajput, Manjushree Anjanappa, and Harikrishna Nakshatri

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A proinflammatory stimulus disrupts hippocampal plasticity and learning via microglial activation and 25-hydroxycholesterol, Yukitoshi Izumi, Anil G. Cashikar, Kathiresan Krishnan, Steven M. Paul, Douglas F. Covey, Steven J. Mennerick, and Charles F. Zorumski

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A randomized controlled trial of Lactobacillus rhamnosus GG on antimicrobial-resistant organism colonization, Adriana M Rauseo, Tiffany Hink, Kimberly A Reske, Sondra M Seiler, Kerry M Bommarito, Victoria J Fraser, Carey-Ann D Burnham, Erik R Dubberke, and CDC Prevention Epicenter Program

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A randomized, placebo-controlled trial assessing the effect of VISBIOME ES probiotic in people with HIV on antiretroviral therapy, Rachel M. Presti and et al

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A rapid motor task-based screening tool for parkinsonism in community-based studies, Wendy W Dlamini, Searles Nielsen, Mwiza Ushe, Gill Nelson, and Brad A Racette

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A real-world observation of antipsychotic effects on brain volumes and intrinsic brain activity in schizophrenia, Yifan Chen, Fay Y Womer, Ruiqi Feng, Xizhe Zhang, Yanbo Zhang, Jia Duan, Miao Chang, Zhiyang Yin, Xiaowei Jiang, Shengnan Wei, Yange Wei, Yanqing Tang, and Fei Wang

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A real-world, prospective, multicenter, single-arm observational study of duloxetine in patients with major depressive disorder or generalized anxiety disorder, Gyorgy Szekeres, Sandor Rozsa, Peter Dome, Gabor Barsony, and Xenia Gonda

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Are Fc gamma receptor polymorphisms important in HIV-1 infection outcomes and latent reservoir size?, Helena Lamptey, Evelyn Y Bonney, Bright Adu, and George B Kyei

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Are prescription misuse and illicit drug use etiologically distinct? A genetically-informed analysis of opioids and stimulants, Genevieve F Dash, Nicholas G Martin, Arpana Agrawal, Michael T Lynskey, and Wendy S Slutske

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A representational similarity analysis of cognitive control during color-word Stroop, Michael C. Freund, Julie M. Bugg, and Todd S. Braver

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Ascending dorsal column sensory neurons respond to spinal cord injury and downregulate genes related to lipid metabolism, Eric E. Ewan, Oshri Avraham, Dan Carlin, Tassia Mangetti Gonçalves, Guoyan Zhao, and Valeria Cavalli

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ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease, Paula D. James, Jorge Di Paola, and et al.

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Assessing the clinical requirement of 2.5% phenylephrine for diagnostic pupil examination, Junsang Cho, Brent Bruck, James C. Liu, and Susan M. Culican