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Submissions from 2020

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Cotrimoxazole prophylaxis increases resistance gene prevalence and α-diversity but decreases β-diversity in the gut microbiome of human immunodeficiency virus-exposed, uninfected infants, Alaric W D'Souza, Eshia Moodley-Govender, Bertram Berla, Tejas Kelkar, Bin Wang, Xiaoqing Sun, Brodie Daniels, Anna Coutsoudis, Indi Trehan, and Gautam Dantas

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Successful administration of sequential TVEC and pembrolizumab followed by temozolomide in immunotherapy refractory intracranial metastatic melanoma with acquired B2M mutation, Karam Khaddour, Joshua Dowling, Jiayi Huang, Martha Council, David Chen, Lynn Cornelius, Tanner Johanns, Sonika Dahiya, and George Ansstas

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Integrated proteogenomic characterization across major histological types of pediatric brain cancer, Francesca Petralia, Liang-Bo Wang, Li Ding, and et al

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A triple-drug treatment regimen to accelerate elimination of lymphatic filariasis: From conception to delivery, Gary J Weil, Julie A Jacobson, and Jonathan D King

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CLIP and massively parallel functional analysis of CELF6 reveal a role in destabilizing synaptic gene mRNAs through interaction with 3' UTR elements, Michael A Rieger, Dana M King, Haley Crosby, Yating Liu, Barak A Cohen, and Joseph D Dougherty

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Neuroplastin modulates anti-inflammatory effects of MANF, Takuya Yagi, Rie Asada, Kohsuke Kanekura, Ave Eesmaa, Maria Lindahl, Mart Saarma, and Fumihiko Urano

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Neutrophil elastase facilitates tumor cell intravasation and early metastatic events, Elena Deryugina, Alexia Carré, Veronica Ardi, Tomoki Muramatsu, Jonas Schmidt, Christine Pham, and James P Quigley

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A clinical epidemiology and molecular attribution evaluation of adenoviruses in pediatric acute gastroenteritis: A case-control study, Kanti Pabbaraju, Raymond Tellier, Xiao-Li Pang, Jianling Xie, Bonita E Lee, Linda Chui, Ran Zhuo, Otto G Vanderkooi, Samina Ali, Phillip I Tarr, Anna Funk, and Stephen B Freedman

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Comparison of upper respiratory viral load distributions in asymptomatic and symptomatic children diagnosed with SARS-CoV-2 infection in pediatric hospital testing programs, Larry K Kociolek, Bijal A Parikh, Ariel Hernandez-Leyva, and et al

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Evaluation of surrogate tests for the presence of mecA-mediated methicillin resistance in Staphylococcus capitis, Staphylococcus haemolyticus, Staphylococcus hominis, and Staphylococcus warneri, Romney M Humphries, Paul Magnano, C A Burnham, Jennifer Dien Bard, Tanis C Dingle, Katrina Callan, and Lars F Westblade

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Longitudinal care cascade outcomes among people eligible for antiretroviral therapy who are newly linking to care in Zambia: A multistate analysis, Aaloke Mody, David V Glidden, Ingrid Eshun-Wilson, Kombatende Sikombe, Sandra Simbeza, Njekwa Mukamba, Paul Somwe, Laura K Beres, Jake Pry, Carolyn Bolton-Moore, Nancy Padian, Charles B Holmes, Izukanji Sikazwe, and Elvin H Geng

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A study protocol for a multicentre, prospective, before-and-after trial evaluating the feasibility of implementing targeted SEDation after initiation of mechanical ventilation in the emergency department (The ED-SED Pilot Trial), Brian M Fuller, Brian W Roberts, Nicholas M Mohr, Ryan D Pappal, Robert J Stephens, Yan Yan, Chris Carpenter, Marin H Kollef, and Michael Simon Avidan

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Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome, Jin-Ju Kim, Jeffrey H Miner, and et al

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Self-administered questionnaire to screen for polycystic ovarian syndrome, Bronwyn S Bedrick, Ashley M Eskew, Jorge E Chavarro, and Emily S Jungheim

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Associations between atrial cardiopathy and cerebral amyloid: The ARIC-PET study, Michelle C Johansen, Thomas H Mosley, David S Knopman, Dean F Wong, Chiadi Ndumele, Amil M Shah, Scott D Solomon, and Rebecca F Gottesman

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Comparative evaluation of clinical manifestations and risk of death in patients admitted to hospital with covid-19 and seasonal influenza: Cohort study, Yan Xie, Benjamin Bowe, Geetha Maddukuri, and Ziyad Al-Aly

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Coronary computed tomography angiography compared with single photon emission computed tomography myocardial perfusion imaging as a guide to optimal medical therapy in patients presenting with stable angina: The RESCUE trial, Arthur E Stillman, Constantine Gatsonis, Joao A C Lima, Tao Liu, Bradley S Snyder, Jean Cormack, Vinay Malholtra, Mitchell D Schnall, James E Udelson, Udo Hoffmann, Pamela K Woodard, and RESCUE investigators

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Human pluripotent stem cell-derived kidney organoids with improved collecting duct maturation and injury modeling, Kohei Uchimura, Haojia Wu, Yasuhiro Yoshimura, and Benjamin D Humphreys

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Neonatal mouse gut metabolites influence Cryptosporidium parvum infection in intestinal epithelial cells, Kelli L VanDussen, Lisa J Funkhouser-Jones, Marianna E Akey, Deborah A Schaefer, Kevin Ackman, Michael W Riggs, Thaddeus S Stappenbeck, and L David Sibley

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Conversational ontology operator: Patient-centric vaccine dialogue management engine for spoken conversational agents, Muhammad Amith, Rebecca Z Lin, Licong Cui, Dennis Wang, Anna Zhu, Grace Xiong, Hua Xu, Kirk Roberts, and Cui Tao

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Protocol for the Prognosticating Delirium Recovery Outcomes Using Wakefulness and Sleep Electroencephalography (P-DROWS-E) study: A prospective observational study of delirium in elderly cardiac surgical patients, S Kendall Smith, Thomas Nguyen, Alyssa K Labonte, MohammadMehdi Kafashan, Orlandrea Hyche, Christian S Guay, Elizabeth Wilson, Courtney W Chan, Anhthi Luong, L Brian Hickman, Bradley A Fritz, Daniel Emmert, Thomas J Graetz, Spencer J Melby, Brendan P Lucey, Yo-El S Ju, Troy S Wildes, Michael S Avidan, and Ben J A Palanca

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YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling, Boksik Cha, Yen-Chun Ho, Xin Geng, Md Riaj Mahamud, Lijuan Chen, Yeunhee Kim, Dongwon Choi, Tae Hoon Kim, Gwendalyn J Randolph, Xinwei Cao, Hong Chen, and R Sathish Srinivasan

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Whole Health Options and Pain Education (wHOPE): A pragmatic trial comparing Whole Health Team vs Primary Care Group Education to promote nonpharmacological strategies to improve pain, functioning, and quality of life in veterans-Rationale, methods, and implementation, Karen H Seal, Kavitha Reddy, and et al.

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Autoregulation of yeast ribosomal proteins discovered by efficient search for feedback regulation, Basab Roy, David Granas, Fredrick Bragg Jr, Jonathan A Y Cher, Michael A White, and Gary D Stormo

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Evaluating the implementation of the SWITCH® school wellness intervention and capacity-building process through multiple methods, Gabriella M McLoughlin, Priscila Candal, Spyridoula Vazou, Joey A Lee, David A Dzewaltowski, Richard R Rosenkranz, Lorraine Lanningham-Foster, Douglas A Gentile, Laura Liechty, Senlin Chen, and Gregory J Welk

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Global hypermethylation of intestinal epithelial cells is a hallmark feature of neonatal surgical necrotizing enterocolitis, Misty Good, Tianjiao Chu, Patricia Shaw, Lora McClain, Austin Chamberlain, Carlos Castro, Jamie M Rimer, Belgacem Mihi, Qingqing Gong, Lila S Nolan, Krista Cooksey, Laura Linneman, Pranjal Agrawal, David N Finegold, and David Peters

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Single-arm prospective interventional study assessing feasibility of using gallium-68 ventilation and perfusion PET/CT to avoid functional lung in patients with stage III non-small cell lung cancer, Nicholas Bucknell, Amir Iravani, and et al

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Macrophage-derived vascular endothelial growth factor-A is integral to neuromuscular junction reinnervation after nerve injury, Chuieng-Yi Lu, Katherine B. Santosa, Albina Jablonka-Shariff, Bianca Vannucci, Anja Fuchs, Isaiah Turnbull, Deng Pan, Matthew D. Wood, and Alison K. Snyder-Warwick

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Impact of a 2-year trial of nutritional ketosis on indices of cardiovascular disease risk in patients with type 2 diabetes, Shaminie J Athinarayanan, Sarah J Hallberg, Amy L McKenzie, Katharina Lechner, Sarah King, James P McCarter, Jeff S Volek, Stephen D Phinney, and Ronald M Krauss

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The key glycolytic enzyme phosphofructokinase is involved in resistance to antiplasmodial glycosides, Gillian M Fisher, Simon A Cobbold, Andrew Jezewski, Emma F Carpenter, Megan Arnold, Annie N Cowell, Erick T Tjhin, Kevin J Saliba, Tina S Skinner-Adams, Marcus C S Lee, Audrey Odom John, Elizabeth A Winzeler, Malcolm J McConville, Sally-Ann Poulsen, and Katherine T Andrews

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Perspectives of scientists on disseminating research findings to non-research audiences, Demetria M McNeal, Russell E Glasgow, Ross C Brownson, Daniel D Matlock, Pamela N Peterson, Stacie L Daugherty, and Christopher E Knoepke

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Roxadustat for CKD-related anemia in non-dialysis patients, Daniel W Coyne and et al.

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Activation of the archaeal ion channel MthK is exquisitely regulated by temperature, Yihao Jiang, Vinay Idikuda, Sandipan Chowdhury, and Baron Chanda

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Approaches to aggressive B-cell lymphomas in less fit patients, Nancy L Bartlett

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Frequency and risk factors of acute kidney injury during diabetic ketoacidosis in children and association with neurocognitive outcomes, Sage R. Myers, Kimberly S. Quayle, and et al

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Comparing the effects of HIV self-testing to standard HIV testing for key populations: A systematic review and meta-analysis, T Charles Witzel, Ingrid Eshun-Wilson, Muhammad S Jamil, Nerissa Tilouche, Carmen Figueroa, Cheryl C Johnson, David Reid, Rachel Baggaley, Nandi Siegfried, Fiona M Burns, Alison J Rodger, and Peter Weatherburn

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Humoral immune responses mediate the development of a restrictive phenotype of chronic lung allograft dysfunction, Keizo Misumi, David S Wheeler, Yoshiro Aoki, Michael P Combs, Russell R Braeuer, Ryuji Higashikubo, Wenjun Li, Daniel Kreisel, Ragini Vittal, Jeffrey Myers, Amir Lagstein, Natalie M Walker, Carol F Farver, and Vibha N Lama

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Stem cell and niche regulation in human short bowel syndrome, Vered A Gazit, Elzbieta A Swietlicki, Miranda U Liang, Adam Surti, Raechel McDaniel, Mackenzie Geisman, David M Alvarado, Matthew A Ciorba, Grant Bochicchio, Obeid Ilahi, John Kirby, William J Symons, Nicholas O Davidson, Marc S. Levin, and Deborah C Rubin

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Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins, Chanjae Lee, Rachael M. Cox, Ophelia Papoulas, Amjad Horani, Kevin Drew, Caitlin C. Devitt, Steven L. Brody, Edward M. Marcotte, and John B. Wallingford

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Acute right ventricular dysfunction in a critically ill patient with COVID-19, Chakradhar Venkata, Senthil Aruchamy, and Jan Kasal

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A large-scale genome-wide association study meta-analysis of cannabis use disorder, Emma C Johnson, Alexander S Hatoum, June He, Kathleen K Bucholz, Louis Fox, Sarah M Hartz, John P Rice, Nancy L Saccone, Laura J Bierut, Richard A Grucza, Andrew C Heath, Pamela A F Madden, Elliot C Nelson, Arpana Agrawal, and et al.

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A management framework for left sided endocarditis: A narrative review, Francesco Nappi, Cristiano Spadaccio, and Marc R. Moon

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A narrative review of early surgery versus conventional treatment for infective endocarditis: Do we have an answer?, Umberto Benedetto, Cristiano Spadaccio, Federico Gentile, Marc R. Moon, and Francesco Nappi

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A narrative review of the interpretation of guidelines for the treatment of infective endocarditis, Umberto Benedetto, Sanjeet Singh Avtaar Singh, Cristiano Spadaccio, Marc R. Moon, and Francesco Nappi

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Antibody profiling of patients with prostate cancer reveals differences in antibody signatures among disease stages, Hemanth K Potluri, Tun Lee Ng, Michael A Newton, Jin Zhang, Christopher A Maher, Peter S Nelson, and Douglas G McNeel

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A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER), Cary D Austin, Kaharu Sumino, and et al.

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Arginine kinetics are altered in a pilot sample of adolescents and young adults with Barth syndrome, W Todd Cade, Kathryn L Bohnert, Adam J Bittel, Shaji J Chacko, Bruce W Patterson, Christina A Pacak, Barry J Byrne, Hilary J Vernon, and Dominic N Reeds

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Cardiac biomarkers during cancer therapy: Practical applications for cardio-oncology, Jose A Alvarez-Cardona, Kathleen W Zhang, Joshua D Mitchell, Vlad G Zaha, Michael J Fisch, and Daniel J Lenihan

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Diagnostic concordance of clinical diagnosis, tissue culture, and histopathology testing for skin and soft tissue infections: A single-center retrospective study, Christina M Herbosa, Trisha S Bhat, Yevgeniy R Semenov, Ilana S Rosman, and Amy C Musiek

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Effect of ulnar collateral ligament reconstruction on pitch accuracy, velocity, and movement in Major League Baseball pitchers, Braden McKnight, Nathanael D Heckmann, Xiao T Chen, Kevork Hindoyan, J Ryan Hill, Graham Goldbeck, Reza Omid, George F Rick Hatch III, and Timothy P Charlton

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Final 5-year findings from the phase 3 HELIOS study of ibrutinib plus bendamustine and rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma, Graeme A M Fraser, Nancy L. Bartlett, and et al

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Incidence and survival for oropharynx and non-oropharynx head and neck cancers among veterans living with HIV, Angela L Mazul, Christine Hartman, Jennifer Kramer, Donna L White, Kathryn Royse, Suchismita Raychaudhury, Vlad Sandulache, Sarah T Ahmed, Peter Richardson, Andrew G Sikora, and Elizabeth Chiao

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Intact microstructure of the right corticostriatal pathway predicts creative ability in healthy adults, Farzaneh Rahmani, Hossein Sanjari Moghaddam, and Mohammad Hadi Aarabi

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International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of ADAMTS13, Ian Mackie, Ilaria Mancini, Joshua Muia, Johanna Kremer Hovinga, Sukesh Nair, Sam Machin, and Ross Baker

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Laparoscopic cytoreductive nephrectomy is associated with significantly improved survival compared with open cytoreductive nephrectomy or targeted therapy alone, Kaidong Zhao, Eric H Kim, Joel M Vetter, James J Hsieh, Ramakrishna Venkatesh, Sam B Bhayani, and R Sherburne Figenshau

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Lower survival after coronary artery bypass in patients who had atrial fibrillation missed by widely used definitions, Giovanni Filardo, Benjamin D Pollock, Briget da Graca, Danielle M Sass, Teresa K Phan, Debbie E Montenegro, Gorav Ailawadi, Vinod H Thourani, and Ralph J Damiano Jr

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Perspectives on patient experience: A national survey of hospitalists, Rafina Khateeb, Angela Keniston, Amber Moore, Christine Hrach, Kimberly A Indovina, Patrick Kneeland, Mark Rudolph, and Marisha Burden

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Positive information facilitates response inhibition in older adults only when emotion is task-relevant, Samantha E Williams, Eric J Lenze, and Jill D Waring

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Prenatal stress exposure and multimodal assessment of amygdala-medial prefrontal cortex connectivity in infants, Kathryn L Humphreys, M C Camacho, Marissa C Roth, and Elizabeth C Estes

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Reducing infant catheterization in the emergency department through clean-catch urine collection., Amanda E Mulcrone, Manas Parikh, and Fahd A Ahmad

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REV-ERBα mediates complement expression and diurnal regulation of microglial synaptic phagocytosis, Percy Griffin, Patrick W. Sheehan, Julie M. Dimitry, Chun Guo, Michael F. Kanan, Jiyeon Lee, Jinsong Zhang, and Erik S. Musiek

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Sequence analysis in Bos taurus reveals pervasiveness of X-Y arms races in mammalian lineages, Jennifer F Hughes, Colin Kremitzki, Catrina Fronick, Tina A Graves-Lindsay, Lucinda Fulton, Wesley C Warren, Richard K Wilson, and et al.

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Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages, Jennifer F Hughes, Colin Kremitzki, Catrina Fronick, Tina A Graves-Lindsay, Lucinda Fulton, Wesley C Warren, Richard K Wilson, and et al

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Spot the difference: Comparing results of analyses from real patient data and synthetic derivatives, Randi E Foraker, Sean C Yu, Aditi Gupta, Andrew P Michelson, Jose A Pineda Soto, Ryan Colvin, Francis Loh, Marin H Kollef, Thomas Maddox, Bradley Evanoff, Hovav Dror, Noa Zamstein, Albert M Lai, and Philip R O Payne

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The effects of early-treated phenylketonuria on volumetric measures of the cerebellum, Kristina Aldridge, Kimberly K Cole, Amanda J Moffitt Gunn, Dawn Peck, Desirée A White, and Shawn E Christ

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The impact of uncorrected mild aortic insufficiency at the time of left ventricular assist device implantation, Yuki Tanaka, Tomohiro Nakajima, Irene Fischer, Fei Wan, Kunal Kotkar, Marc R Moon, Ralph J Damiano Jr, Muhammad F Masood, and Akinobu Itoh

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The quest for the optimal surgical management of tricuspid valve endocarditis in the current era: A narrative review, Francesco Nappi, Cristiano Spadaccio, Christos Mihos, Kasra Shaikhrezai, Christophe Acar, and Marc R. Moon

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Carfilzomib, lenalidomide, and dexamethasone plus transplant in newly diagnosed multiple myeloma, Jagoda K Jasielec, Ravi Vij, and et al.

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Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1, Ravi Chopra, David D Bushart, John P Cooper, Dhananjay Yellajoshyula, Logan M Morrison, Haoran Huang, Hillary P Handler, Luke J Man, Warunee Dansithong, Daniel R Scoles, Stefan M Pulst, Harry T Orr, and Vikram G Shakkottai

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DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopmental disorders, Diana L Christian, Dennis Y Wu, Jenna R Martin, J Russell Moore, Yiran R Liu, Adam W Clemens, Sabin A Nettles, Nicole M Kirkland, Thomas Papouin, Cheryl A Hill, David F Wozniak, Joseph D Dougherty, and Harrison W Gabel

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The intriguing interaction of Escherichia coli with the host environment and innovative strategies to interfere with colonization: A summary of the 2019 E. coli and the Mucosal Immune System Meeting, Eric Cox, Meryem Aloulou, James M Fleckenstein, Christina Schäffer, Åsa Sjöling, Stephanie Schüller, Kurt Hanevik, Bert Devriendt, Weiping Zhang, Ann-Mari Svennerholm, and Edward G Dudley

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Transcriptional remodeling patterns in murine dendritic cells infected with Paracoccidioides brasiliensis: More is not necessarily better, Calliandra M de-Souza-Silva, Fabián Andrés Hurtado, Aldo Henrique Tavares, Getúlio P de Oliveira, Taina Raiol, Christiane Nishibe, Daniel Paiva Agustinho, Nalvo Franco Almeida, Maria Emília Machado Telles Walter, André Moraes Nicola, Anamélia Lorenzetti Bocca, Patrícia Albuquerque, and Ildinete Silva-Pereira

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Central nervous system pathology in preclinical MPS IIIB dogs reveals progressive changes in clinically relevant brain regions, Martin T Egeland, Marta M Tarczyluk-Wells, Melissa M Asmar, Evan G Adintori, Roger Lawrence, Elizabeth M Snella, Jackie K Jens, Brett E Crawford, Jill C M Wait, Emma McCullagh, Jason Pinkstaff, Jonathan D Cooper, and N Matthew Ellinwood

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Design and development of the Pediatric Urology Recovery After Surgery Endeavor (PURSUE) multicentre pilot and exploratory study, Kyle O Rove, Andrew C Strine, Duncan T Wilcox, Gino J Vricella, Timothy P Welch, Brian VanderBrink, David I Chu, Rajeev Chaudhry, Rebecca S Zee, Megan A Brockel, and PURSUE Study group

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Mild traumatic brain injury is associated with effect of inflammation on structural changes of default mode network in those developing chronic pain, Xuan Niu, Lijun Bai, Yingxiang Sun, Yuan Wang, Guanghui Bai, Bo Yin, Shan Wang, Shuoqiu Gan, Xiaoyan Jia, and Hongjuan Liu

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A phase 1b study of AFM13 in combination with pembrolizumab in patients with relapsed or refractory Hodgkin lymphoma, Nancy L Bartlett and et al.

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Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease, Laura Ibanez, Jorge A Bahena, Chengran Yang, Umber Dube, Fabiana H G Farias, John P Budde, Kristy Bergmann, Carol Brenner-Webster, John C Morris, Richard J Perrin, Nigel J Cairns, John O'Donnell, Rebecca Miller, Albert A Davis, Paul Kotzbauer, Meghan C Campbell, Joel S Perlmutter, Oscar Harari, Carlos Cruchaga, Bruno A Benitez, and et al.

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Full-length TrkB variant in NSCLC is associated with brain metastasis, Mariangela Lombardi, Michela D'Ascanio, Stefania Scarpino, Davide Scozzi, Marco Giordano, Leopoldo Costarelli, Enrico Rathina Raj, Rita Mancini, Giuseppe Cardillo, Vittorio Cardaci, Marta Innammorato, Andrea Vecchione, and Alberto Ricci

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High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures, Kyaw Thu Minn, Yuheng C. Fu, Shenghua He, Sabine Dietmann, Steven C. George, Mark A. Anastasio, Samantha A. Morris, and Lilianna Solnica-Krezel

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Inflammasomes within hyperactive murine dendritic cells stimulate long-lived T cell-mediated anti-tumor immunity, Dania Zhivaki, Francesco Borriello, Ohn A Chow, Benjamin Doran, Ira Fleming, Derek J Theisen, Paris Pallis, Alex K Shalek, Caroline L Sokol, Ivan Zanoni, and Jonathan C Kagan

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Requisite chromatin remodeling for myeloid and erythroid lineage differentiation from erythromyeloid progenitors, Jun Wu, Karen Krchma, Hyung Joo Lee, Sairam Prabhakar, Xiaoli Wang, Haiyong Zhao, Xiaoyun Xing, Rho H Seong, Daved H Fremont, Maxim N Artyomov, Ting Wang, and Kyunghee Choi

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Structure of the receptor binding domain of EnvP(b)1, an endogenous retroviral envelope protein expressed in human tissues, Kevin R McCarthy, Joseph L Timpona, Simon Jenni, Louis-Marie Bloyet, Vesna Brusic, Welkin E Johnson, Sean P J Whelan, and Lindsey R Robinson-McCarthy

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AnemoCheck-LRS: An optimized, color-based point-of-care test to identify severe anemia in limited-resource settings, Marina S Perez-Plazola, Erika A Tyburski, Luke R Smart, Thad A Howard, Amanda Pfeiffer, Russell E Ware, Wilbur A Lam, and Patrick T McGann

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Metachronous cutaneous squamous cell carcinoma in a young patient as the only presenting symptom to uncover Lynch syndrome with MLH1 germline mutation, Karam Khaddour, Ryan C Fields, Michael Ansstas, Ilana S Rosman, and George Ansstas

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Non-negative data-driven mapping of structural connections with application to the neonatal brain, E Thompson, A R Mohammadi-Nejad, E C Robinson, J L R Andersson, S Jbabdi, M F Glasser, M Bastiani, and S N Sotiropoulos

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A praziquantel treatment study of immune and transcriptome profiles in Schistosoma haematobium-infected Gabonese schoolchildren, Lucja A Labuda, Ayola A Adegnika, Bruce A Rosa, John Martin, Ulysse Ateba-Ngoa, Abena Serwaa Amoah, Honorine Mbenkep Lima, Lynn Meurs, Moustapha Mbow, Mikhael D Manurung, Jeannot F Zinsou, Hermelijn H Smits, Peter G Kremsner, Makedonka Mitreva, and Maria Yazdanbakhsh

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Multivariate lesion-behavior mapping of general cognitive ability and its psychometric constituents, Mark Bowren, Ralph Adolphs, Joel Bruss, Kenneth Manzel, Maurizio Corbetta, Daniel Tranel, and Aaron D. Boes

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Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser, Keerthana Gnanapradeepan, Julia I-Ju Leu, Subhasree Basu, Thibaut Barnoud, Madeline Good, Joyce V. Lee, William J. Quinn, Che-Pei Kung, Rexford Ahima, Joseph A. Baur, Kathryn E. Wellen, Qin Liu, Zachary T. Schug, Donna L. George, and Maureen E. Murphy

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Kir6.1- and SUR2-dependent KATP over-activity disrupts intestinal motility in murine models of Cantu Syndrome, Nathaniel W York, Helen Parker, Zili Xie, David Tyus, Maham A Waheed, Zihan Yan, Dorothy K Grange, Maria S Remedi, Sarah K England, Hongzhen Hu, and Colin G Nichols

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Prepronociceptin-expressing neurons in the extended amygdala encode and promote rapid arousal responses to motivationally salient stimuli, Jose Rodriguez-Romaguera, Michael R Bruchas, and et al

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TFEB transcriptional responses reveal negative feedback by BHLHE40 and BHLHE41, Kimberly L Carey, Geraldine L C Paulus, Lingfei Wang, Dale R Balce, Jessica W Luo, Phil Bergman, Ianina C Ferder, Lingjia Kong, Nicole Renaud, Shantanu Singh, Maria Kost-Alimova, Beat Nyfeler, Kara G Lassen, Herbert W Virgin, and Ramnik J Xavier

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Antimicrobial resistance in enteric bacteria: Current state and next-generation solutions, M J Wallace, S R S Fishbein, and G Dantas

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Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection, Jennifer Foulke-Abel, Huimin Yu, Laxmi Sunuwar, Ruxian Lin, James M Fleckenstein, James B Kaper, and Mark Donowitz

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Treatment of epithelial ovarian cancer, Lindsay Kuroki and Saketh R Guntupalli

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MYH3-associated distal arthrogryposis zebrafish model is normalized with para-aminoblebbistatin, Julia Whittle, Lilian Antunes, Mya Harris, Zachary Upshaw, Diane S Sepich, Aaron N Johnson, Mayssa Mokalled, Lilianna Solnica-Krezel, Matthew B Dobbs, and Christina A Gurnett

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Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease, Charles D Chen, Timothy R Holden, Brian A Gordon, Erin E Franklin, Yan Li, Dean W Coble, Hongbo Luo, Randall J Bateman, Dominantly Inherited Alzheimer Network (DIAN) and for the Dominantly Inherited Alzheimer Network Trials Unit (DIAN-TU), Beau M Ances, Richard J Perrin, Tammie L S Benzinger, Nigel J Cairns, and John C Morris

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Urban-rural disparities in access to low-dose computed tomography lung cancer screening in Missouri and Illinois, Karthik W Rohatgi, Christine M Marx, Marquita W Lewis-Thames, Jingxia Liu, Graham A Colditz, and Aimee S James

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A multisite study of a breast density deep learning model for full-field digital mammography and synthetic mammography, Thomas P Matthews, Sadanand Singh, Brent Mombourquette, Jason Su, Meet P Shah, Stefano Pedemonte, Aaron Long, David Maffit, Jenny Gurney, Rodrigo Morales Hoil, Nikita Ghare, Douglas Smith, Stephen M Moore, Susan C Marks, and Richard L Wahl

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Genetics and geography of leukocyte telomere length in sub-Saharan Africans, Steven C Hunt, Michael A Province, and et al.

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Airway microbiota-host interactions regulate secretory leukocyte protease inhibitor levels and influence allergic airway inflammation, Natalia Jaeger, Ryan T McDonough, Anne L Rosen, Ariel Hernandez-Leyva, Naomi G Wilson, Michael A Lint, Emilie V Russler-Germain, Jiani N Chai, Leonard B Bacharier, Chyi-Song Hsieh, and Andrew L Kau