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Submissions from 2022

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The social cerebellum: A large-scale investigation of functional and structural specificity and connectivity, Athanasia Metoki, Yin Wang, and Ingrid R Olson

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Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry, Antoine Baudrimont, Dimitra Paouneskou, Ariz Mohammad, Raffael Lichtenberger, Joshua Blundon, Yumi Kim, Markus Hartl, Sebastian Falk, Tim Schedl, and Verena Jantsch

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Repeated endo-tracheal tube disconnection generates pulmonary edema in a model of volume overload: An experimental study, Bhushan H Katira, Doreen Engelberts, Sheena Bouch, Jordan Fliss, Luca Bastia, Kohei Osada, Kim A Connelly, Marcelo B P Amato, Niall D Ferguson, Wolfgang M Kuebler, Brian P Kavanagh, Laurent J Brochard, and Martin Post

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Assessing infant cognition in field settings using eye-tracking: A pilot cohort trial in Sierra Leone, Jukka Leppänen, Julius Butcher, Claire Godbout, Kevin Stephenson, D. Taylor Hendrixson, Stacy Griswold, Beatrice Rogers, Patrick Webb, Aminata Koroma, and Mark Manary

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Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine, Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, and James M Fleckenstein

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Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine, Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, and James M Fleckenstein

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Sustained efficacy and safety of burosumab, a monoclonal antibody to FGF23, in children with X-linked hypophosphatemia, Agnès Linglart, Erik A Imel, Michael P Whyte, Anthony A Portale, Wolfgang Högler, Annemieke M Boot, Raja Padidela, William Van't Hoff, Gary S Gottesman, Angel Chen, Alison Skrinar, Mary Scott Roberts, and Thomas O Carpenter

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Unilateral cleft lip repair: Technical maneuvers to achieve vermilion and mucosal height, Sarah N Chiang, Ema Zubovic, Gary B Skolnick, and Kamlesh B Patel

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Cardiac outcomes of subjects on adjuvant trastuzumab emtansine vs paclitaxel in combination with trastuzumab for stage I HER2-positive breast cancer (ATEMPT) study (TBCRC033): A randomized controlled trial, Romualdo Barroso-Sousa, Ron Bose, and et al

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Risks of mental health outcomes in people with covid-19: Cohort study, Yan Xie, Evan Xu, and Ziyad Al-Aly

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A diffusion MRI-based spatiotemporal continuum of the embryonic mouse brain for probing gene-neuroanatomy connections, Dan Wu, Linda J Richards, Zhiyong Zhao, Zuozhen Cao, Wanrong Luo, Wei Shao, Song-Hai Shi, Michael I Miller, Susumu Mori, Seth Blackshaw, and Jiangyang Zhang

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Cell specific peripheral immune responses predict survival in critical COVID-19 patients, Junedh M Amrute, Alexandra M Perry, Gautam Anand, Carlos Cruchaga, Karl G Hock, Christopher W Farnsworth, Gwendalyn J Randolph, Kory J Lavine, and Ashley L Steed

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Enhancing task fMRI preprocessing via individualized model-based filtering of intrinsic activity dynamics, Matthew F Singh, Anxu Wang, Michael Cole, ShiNung Ching, and Todd S Braver

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Filtering respiratory motion artifact from resting state fMRI data in infant and toddler populations, Sydney Kaplan, Dominique Meyer, Dimitrios Alexopoulos, Deanna M Barch, Adam T Eggebrecht, Jeanette K Kenley, Cynthia E Rogers, Muriah D Wheelock, Christopher D Smyser, and et al.

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Health-related quality of life in older patients with advanced heart failure: Findings from the SUSTAIN-IT study, Kathleen L Grady, Justin Hartupee, and et al

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Hydraulic permeability and compressive properties of porcine and human synovium, Milad Rohanifar, Benjamin B Johnston, Alexandra L Davis, Young Guang, Kayla Nommensen, James A J Fitzpatrick, Christine N Pham, and Lori A Setton

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Relationships between correlated spikes, oxygen and LFP in the resting-state primate, Jingfeng M Li, Benjamin T Acland, Alexander S Brenner, William J Bentley, and Lawrence H Snyder

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The history and innovations of blood vessel anastomosis, William R Moritz, Shreya Raman, Sydney Pessin, Cameron Martin, Xiaowei Li, Amanda Westman, and Justin M Sacks

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Therapeutic efficacy of 177Lu-labeled A20FMDV2 peptides targeting ανβ6, Truc Thao Huynh, Sreeja Sreekumar, Cedric Mpoy, and Buck Edward Rogers

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Two-tier care pathways for liver fibrosis associated to non-alcoholic fatty liver disease in HIV mono-infected patients, Giada Sebastiani, Jovana Milic, Adriana Cervo, Sahar Saeed, Thomas Krahn, Dana Kablawi, Al Shaima Al Hinai, Bertrand Lebouché, Philip Wong, Marc Deschenes, Claudia Gioè, Antonio Cascio, Giovanni Mazzola, and Giovanni Guaraldi

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Stain-free detection of embryo polarization using deep learning, Cheng Shen, Adiyant Lamba, Meng Zhu, Ray Zhang, Magdalena Zernicka-Goetz, and Changhuei Yang

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Apparent sunk cost effect in rational agents, Torben Ott, Paul Masset, Thiago S Gouvêa, and Adam Kepecs

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Intracranial internal carotid artery calcification is not predictive of future cognitive decline, Farzaneh Rahmani, Marina Nguyen, Charles D Chen, Nicole McKay, Aylin Dincer, Nelly Joseph-Mathurin, Gengsheng Chen, Jingxia Liu, Hilary L P Orlowski, John C Morris, and Tammie L S Benzinger

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IκB-ζ signaling promotes chondrocyte inflammatory phenotype, senescence, and erosive joint pathology, Manoj Arra, Gaurav Swarnkar, Yael Alippe, Gabriel Mbalaviele, and Yousef Abu-Amer

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Community-level factors associated with geographic access to food retailers offering nutrition incentives in Chicago, Illinois, Chelsea R Singleton, Fikriyah Winata, Alexandra M Roehll, Isa Adamu, and Gabriella M McLoughlin

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Single-agent mosunetuzumab shows durable complete responses in patients with relapsed or refractory B-cell lymphomas: Phase I dose-escalation study, Lihua E Budde, Nancy L Bartlett, and et al

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Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes, Susheel K Gunasekar, Litao Xie, Ashutosh Kumar, Juan Hong, Chen Kang, Joshua Maurer, John Heebink, Phillip Key, Joseph W Beals, Gordon I Smith, Samuel Klein, Rajan Sah, and et al

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The association between HIV status, estradiol, and sex hormone binding globulin among premenopausal women in the Women's Interagency HIV Study, Sally B Coburn, Jodie Dionne-Odom, Maria L Alcaide, Caitlin A Moran, Lisa Rahangdale, Elizabeth T Golub, Leslie Stewart Massad, Dominika Seidman, Katherine G Michel, Howard Minkoff, Kerry Murphy, Todd T Brown, Kala Visvanathan, Bryan Lau, and Keri N Althoff

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Disseminated infection due to Neocosmospora (Fusarium) falciformis in a patient with acute myelogenous leukemia, Ra'ed Jabr, Rachael M Liesman, Venkata Rakesh Sethapati, D Matthew Shoemaker, Andrej Spec, and Wissam El Atrouni

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Spatiotemporal expression of regulatory kinases directs the transition from mitosis to cellular morphogenesis in Drosophila, Shuo Yang, Jennifer McAdow, Yingqiu Du, Jennifer Trigg, Paul H Taghert, and Aaron N Johnson

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A dominant negative variant of RAB5B disrupts maturation of surfactant protein B and surfactant protein C, Huiyan Huang, Jiehong Pan, Ariz Mohammad, Tao Huang, Anika G Lindsey, Hyori Kim, Jian Chen, Avinash Ramu, Stephanie A Morrison, Zachary D Dawson, Alex Z Hu, Eric Tycksen, Gary A Silverman, Dustin Baldridge, Jennifer A Wambach, Stephen C. Pak, Steven L Brody, Tim Schedl, and et al

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DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3, Corina M. Borza, Gema Bolas, Fabian Bock, Xiuqi Zhang, Favour C Akabogu, Ming-Zhi Zhang, Mark de Caestecker, Min Yang, Haichun Yang, Ethan Lee, Leslie Gewin, Agnes B Fogo, W Hayes McDonald, Roy Zent, and Ambra Pozzi

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Outcome of allogeneic transplantation for mature T-cell lymphomas: Impact of donor source and disease characteristics, Mehdi Hamadani, Amanda F Cashen, and et al

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Regulation of the double-stranded RNA response through ADAR1 licenses metaplastic reprogramming in gastric epithelium, José B. Sáenz, Nancy Vargas, Charles J. Cho, and Jason C. Mills

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Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma, Arja Ray, Mackenzie K. Callaway, Nelson J. Rodríguez-Merced, Alexandra L. Crampton, Marjorie Carlson, Kenneth B. Emme, Ethan A. Ensminger, Alexander A. Kinne, Jonathan H. Schrope, Haley R. Rasmussen, Hong Jiang, David G. DeNardo, David K. Wood, and Paolo P. Provenzano

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Live-dead assay on unlabeled cells using phase imaging with computational specificity, Chenfei Hu, Shenghua He, Young Jae Lee, Yuchen He, Edward M Kong, Hua Li, Mark A Anastasio, and Gabriel Popescu

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Videos of sipuleucel-T programmed T cells lysing cells that express prostate cancer target antigens, Adam S Kibel, Brant A Inman, Russell K Pachynski, Tuyen Vu, Nadeem A Sheikh, and Daniel P Petrylak

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Protocol for development of a core outcome set for clinical trials in melasma, Sarah Ibrahim, Bianca Kang, Daniel Schlessinger, Sarah Chiren, Jennifer Tang, Jamie Kirkham, Jochen Schmitt, Emily Poon, Ian Maher, Joseph Sobanko, Todd Cartee, and Murad Alam

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Using smartphones to reduce research burden in a neurodegenerative population and assessing participant adherence: A randomized clinical trial and two observational studies, Anna L Beukenhorst, Katherine M Burke, Zoe Scheier, Timothy M Miller, Sabrina Paganoni, Mackenzie Keegan, Ella Collins, Kathryn P Connaghan, Anna Tay, James Chan, James D Berry, and Jukka-Pekka Onnela

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Genetically stable CRISPR-based kill switches for engineered microbes, Austin G Rottinghaus, Aura Ferreiro, Skye R S Fishbein, Gautam Dantas, and Tae Seok Moon

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Myeloid cell interferon responses correlate with clearance of SARS-CoV-2, Dhiraj K Singh, Ekaterina Aladyeva, Shibali Das, Bindu Singh, Ekaterina Esaulova, Amanda Swain, Mushtaq Ahmed, Journey Cole, Chivonne Moodley, Smriti Mehra, Larry S Schlesinger, Maxim N Artyomov, Shabaana A Khader, and Deepak Kaushal

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Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden, Celia A McKee, Jiyeon Lee, Yuqi Cai, Takashi Saito, Takaomi Saido, and Erik S Musiek

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Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate, Arpan Parichha, Varun Suresh, Mallika Chatterjee, Aditya Kshirsagar, Lihi Ben-Reuven, Tsviya Olender, M Mark Taketo, Velena Radosevic, Mihaela Bobic-Rasonja, Sara Trnski, Michael J Holtzman, Nataša Jovanov-Milosevic, Orly Reiner, and Shubha Tole

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Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis, Thomas E Mahan, Chao Wang, Xin Bao, Ankit Choudhury, Jason D Ulrich, and David M Holtzman

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Single circulating-tumor-cell-targeted sequencing to identify somatic variants in liquid biopsies in non-small-cell lung cancer patients, Mouadh Barbirou, Amanda Miller, Yariswamy Manjunath, Arturo B Ramirez, Nolan G Ericson, Kevin F Staveley-O'Carroll, Jonathan B Mitchem, Wesley C Warren, Aadel A Chaudhuri, Yi Huang, Guangfu Li, Peter J Tonellato, and Jussuf T Kaifi

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Alterations of host-gut microbiome interactions in multiple sclerosis, Claudia Cantoni, Laura Ghezzi, Emily Evans, Li Deng, Alberto Locca, Robert Mikesell, Kathleen Obert, Amber Salter, Anne H Cross, Phillip I Tarr, Laura Piccio, Yanjiao Zhou, and et al

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Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model, Riti Sharan, Allison N Bucsan, Shabaana A Khader, and et al

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A prospective multicenter evaluation of initial treatment choice in metastatic renal cell carcinoma prior to the immunotherapy era: The MaRCC Registry experience, Brian A. Costello, Russell K. Pachynski, and et al.

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Brain stimulation treatments in epilepsy: Basic mechanisms and clinical advances, Thomas J. Foutz and Michael Wong

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Coronavirus disease 2019 (COVID-19) research agenda for healthcare epidemiology, Lona Mody, Hilary M Babcock, Jennie H Kwon, and et al

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Dear reviewers: Responses to common reviewer critiques about infant neuroimaging studies, Marta Korom, M Catalina Camacho, Courtney A Filippi, Roxane Licandro, Lucille A Moore, Alexander Dufford, Lilla Zöllei, Alice M Graham, Marisa Spann, Brittany Howell, FIT'NG, Sarah Shultz, and Dustin Scheinost

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Depression Is transiently increased in patients undergoing two-stage revision arthroplasty, Ryan J Furdock, Bharadwaj Jilakara, Tyler J Moon, Neelansh Bute, Lee Rhea, Douglas McDonald, and Cara A Cipriano

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Echocardiographic and clinical predictors of cardiac amyloidosis: Limitations of apical sparing, Douglas Kyrouac, Walter Schiffer, Brandon Lennep, Nicole Fergestrom, Kathleen W Zhang, John Gorcsan III, Daniel J Lenihan, and Joshua D Mitchell

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Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria-causing parasites, Philip M Frasse, Justin J Miller, Alexander J Polino, Ebrahim Soleimani, Jian-She Zhu, David L Jakeman, Joseph M Jez, Daniel E Goldberg, and Audrey R Odom John

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Fractality of tics as a quantitative assessment tool for Tourette syndrome, Payton Beeler, Nicholas O Jensen, Soyoung Kim, Amy Robichaux-Viehoever, Bradley L Schlaggar, Deanna J Greene, Kevin J. Black, and Rajan K Chakrabarty

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Host cell-intrinsic innate immune recognition of SARS-CoV-2, Emily A Madden and Michael S Diamond

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Hypoxia inhibits colonic uptake of the microbiota-generated forms of vitamin B1 via HIF-1α-mediated transcriptional regulation of their transporters, Subrata Sabui, Kalidas Ramamoorthy, Jose M Romero, Rita D Simoes, James M Fleckenstein, and Hamid M Said

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Identification of novel mitochondrial pyruvate carrier inhibitors by homology modeling and pharmacophore-based virtual screening, Lamees Hegazy, Lauren Gill, Kelly Pyles, Christopher Kaiho, Sophia Kchouk, Brian Finck, Kyle McCommis, and Bahaa Elgendy

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Impact of the COVID-19 pandemic on referral to and delivery of gynecologic oncology care, Shaina F Bruce, Bridget Huysman, Jinai Bharucha, L Stewart Massad, Mary M Mullen, Andrea R Hagemann, Katherine C Fuh, Carolyn K McCourt, Premal H Thaker, Dineo Khabele, Matthew A Powell, David G Mutch, and Lindsay M Kuroki

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Importance of the intersection of age and sex to understand variation in incidence and survival for primary malignant gliomas, Gi-Ming Wang, Gino Cioffi, Nirav Patil, Kristin A Waite, Robert Lanese, Quinn T Ostrom, Carol Kruchko, Michael E Berens, James R Connor, Justin D Lathia, Joshua B Rubin, and Jill S Barnholtz-Sloan

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Liposomal phytohemagglutinin: In vivo T-cell activator as a novel pan-cancer immunotherapy, Kinan Alhallak, Jennifer Sun, Barbara Muz, Amanda Jeske, Julie O'Neal, Julie K Ritchey, Samuel Achilefu, John F DiPersio, and Abdel Kareem Azab

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Macrophage global metabolomics identifies cholestenone as host/pathogen cometabolite present in human Mycobacterium tuberculosis infection, Pallavi Chandra, Héloise Coullon, Mansi Agarwal, Charles W Goss, and Jennifer A Philips

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Measurement matters: An individual differences examination of family socioeconomic factors, latent dimensions of children's experiences, and resting state functional brain connectivity in the ABCD sample, Meriah L DeJoseph, Max P Herzberg, Robin D Sifre, Daniel Berry, and Kathleen M Thomas

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Measurement of gender and sexuality in the Adolescent Brain Cognitive Development (ABCD) study, Alexandra S Potter, Hailee Jefferys, and et al

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Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice, Wesley T Hodges, Chaowapong Jarasvaraparn, Daniel Ferguson, Kristine Griffett, Lauren E Gill, Yana Chen, Ma Xenia G Ilagan, Lamees Hegazy, Bahaa Elgendy, Kevin Cho, Gary J Patti, Kyle S McCommis, and Brian N Finck

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Neurotoxicity: A rare side effect of programmed cell death 1 (PD-1) inhibitors, Syed Ehsanullah, Syed Hasan, Faran S Polani, Syeda Zarmeena Rashid, and Syed Ijlal Ahmed

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No difference in radiologic outcomes for natalizumab patients treated with extended interval dosing compared with standard interval dosing: Real-world evidence from MS PATHS, Lana Zhovtis Ryerson, Robert T. Naismith, Lauren B. Krupp, Leigh E. Charvet, Shirley Liao, Elizabeth Fisher, Carl de Moor, James R. Williams, and Nolan Campbell

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Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer, Andrew J Wilson, Vijayalaxmi G Gupta, Qi Liu, Fiona Yull, Marta A Crispens, and Dineo Khabele

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Preschool sleep and depression interact to predict gray matter volume trajectories across late childhood to adolescence, Caroline Hoyniak, Diana J Whalen, Rebecca Tillman, Joan L Luby, and Deanna M Barch

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Prevalence, mechanisms, and return to sport after isolated popliteus injuries in athletes: A systematic review, Caellagh Morrissey and Derrick Knapik

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Prevalence of borderline acetabular dysplasia in symptomatic and asymptomatic populations: A systematic review and meta-analysis, Serena Freiman, Maria Schwabe, Lucas Fowler, John Clohisy, and Jeffrey Nepple

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Protein phosphatase 2A restrains DLK signaling to promote proper Drosophila synaptic development and mammalian cortical neuron survival, Margaret Hayne and Aaron DiAntonio

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Quantifying regional α -synuclein, amyloid β, and tau accumulation in Lewy body dementia, Rebecca L Miller, Dhruva D Dhavale, Jennifer Y O'Shea, Kristin M Andruska, Jialu Liu, Erin E Franklin, Chandana Buddhala, Susan K Loftin, John R Cirrito, Richard J Perrin, Nigel J Cairns, Meghan C Campbell, Joel S Perlmutter, and Paul T Kotzbauer

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RAS and beyond: The many faces of the neurofibromatosis type 1 protein, Corina Anastasaki, Paola Orozco, and David H Gutmann

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rPOP: Robust PET-Only Processing of community acquired heterogeneous amyloid-PET data, Leonardo Iaccarino, Renaud La Joie, Robert Koeppe, Barry A Siegel, Bruce E Hillner, Constantine Gatsonis, Rachel A Whitmer, Maria C Carrillo, Charles Apgar, Monica R Camacho, Rachel Nosheny, Gil D Rabinovici, and Alzheimer's Disease Neuroimaging Initiative

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RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells, Orsola Di Martino, Margaret A. Ferris, Gayla Hadwiger, Soyi Sarkar, Anh Vu, María P. Menéndez-Gutiérrez, Mercedes Ricote, and John S Welch

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Safety and efficacy of mass drug administration with a single-dose triple-drug regimen of albendazole + diethylcarbamazine + ivermectin for lymphatic filariasis in Papua New Guinea: An open-label, cluster-randomised trial, Livingstone Tavul, Kobie O'Brian, Gary J. Weil, Charles W. Goss, and et al

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Significant variations in surgical construct and return to sport protocols with syndesmotic injuries: An ISAKOS global perspective, Kenneth J. Hunt; Jonathan Bartolomei; Shanthan C. Challa; Jeremy J. McCormick; Pieter D'Hooghe; Michael Tuffiash; Annunziato Amendola; and ISAKOS Leg, Ankle Foot Committee

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The ASCC2 CUE domain in the ALKBH3-ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin, Patrick M Lombardi, Timur Rusanov, Rebecca Rodell, Nima Mosammaparast, and et al

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The Emotional Word-Emotional Face Stroop task in the ABCD study: Psychometric validation and associations with measures of cognition and psychopathology, Harry R Smolker, Kai Wang, Monica Luciana, James M Bjork, Raul Gonzalez, Deanna M Barch, Erin C McGlade, Roselinde H Kaiser, Naomi P Friedman, John K Hewitt, and Marie T Banich

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The foundations and development of lipidomics, Xianlin Han and Richard W Gross

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Utility of COVID-19 antigen testing in the emergency department, W Frank Peacock, Stacey L House, and et al.

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Validation of actigraphy for sleep measurement in children with cerebral palsy, Bing Xue, Amy Licis, Jill Boyd, Catherine R Hoyt, and Yo-El S Ju

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β Cell function and plasma insulin clearance in people with obesity and different glycemic status, Bettina Mittendorfer, Bruce W Patterson, Gordon I Smith, Mihoko Yoshino, and Samuel Klein

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Incidence of emergency department visits for electric rental scooters using detailed ridership data, Chelsea Williams, Cindy C Bitter, Steven Lorber, Caleb R Overfelt, Holly Zehfus, Andrea Spangler, Valerie Lew, Lawrence M Lewis, and Rosanne S Naunheim

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Racial and ethnic minorities have a lower prevalence of airflow obstruction than non-Hispanic Whites, Akshay Sood, Hans Petersen, Congjian Liu, Orrin Myers, Xin Wang Shore, Bobbi A Gore, Rodrigo Vazquez-Guillamet, Linda S Cook, Paula Meek, and Yohannes Tesfaigzi

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Gene expression predicts dormant metastatic breast cancer cell phenotype, Qihao Ren, Weng Hua Khoo, Alexander P Corr, Tri Giang Phan, Peter I Croucher, and Sheila A Stewart

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Age-related changes and longitudinal stability of individual differences in ABCD Neurocognition measures, Andrey P Anokhin, Deanna Barch, James T Kennedy, and et al

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Analysis of non-relapsed and relapsed adult type granulosa cell tumors suggests stable transcriptomes during tumor progression, Noora Andersson, Ulla-Maija Haltia, Anniina Färkkilä, Swee Chong Wong, Katja Eloranta, David B Wilson, Leila Unkila-Kallio, Marjut Pihlajoki, Antti Kyrönlahti, and Markku Heikinheimo

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Computational genomics in the era of precision medicine: Applications to variant analysis and gene therapy, Yung-Chun Wang, Julie Choi, Shujuan Zhao, Mariam Khanfar, Kuangying Yang, Po-Ying Fu, Max Wrubel, Xiaobing Yu, Sheng Chih Jin, and et al

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Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways, Donald L Elbert, Bruce W Patterson, Brendan P Lucey, Tammie L S Benzinger, and Randall J Bateman

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Hierarchical and nonhierarchical features of the mouse visual cortical network, Rinaldo D D'Souza, Quanxin Wang, Weiqing Ji, Andrew M Meier, Henry Kennedy, Kenneth Knoblauch, and Andreas Burkhalter

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Inhibiting Mycobacterium abscessus cell wall synthesis: Using a novel diazabicyclooctane β-lactamase inhibitor to augment β-lactam action, Khalid M Dousa, David C Nguyen, Sebastian G Kurz, Magdalena A Taracila, Christopher R Bethel, William Schinabeck, Barry N Kreiswirth, Sheldon T Brown, W Henry Boom, Richard S Hotchkiss, Kenneth E Remy, Frank J Jacono, Charles L Daley, Steven M Holland, Alita A Miller, and Robert A Bonomo

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Longitudinal study after Sputnik V vaccination shows durable SARS-CoV-2 neutralizing antibodies and reduced viral variant escape to neutralization over time, María M Gonzalez Lopez Ledesma, Paul W Rothlauf, Zhuoming Liu, Louis-Marie Bloyet, Marjorie Cornejo Pontelli, and et al

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Pevonedistat targets malignant cells in myeloproliferative neoplasms in vitro and in vivo via NFκB pathway inhibition, Tim Kong, Angelo B A Laranjeira, Taylor B Collins, Elisa S De Togni, Abigail J Wong, Mary C Fulbright, Marianna Ruzinova, Hamza Celik, Grant A Challen, Daniel A C Fisher, and Stephen T Oh

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Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors, Clara Sze Man Tang, Mimmi Mononen, Wai-Yee Lam, Sheng Chih Jin, Xuehan Zhuang, Maria-Mercè Garcia-Barcelo, Qiongfen Lin, Yujia Yang, Makoto Sahara, Elif Eroglu, Kenneth R. Chien, Haifa Hong, Paul Kwong Hang Tam, and Peter J. Gruber

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Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis, Brandon M. Lane, Andrew F. Malone, and et al.

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T Cell Subtype Profiling measures exhaustion and predicts anti-PD-1 response, Ian Schillebeeckx, Jon Earls, Kevin C Flanagan, Jeffrey Hiken, Alex Bode, Jon R Armstrong, David N Messina, Douglas Adkins, Jessica Ley, Ilaria Alborelli, Philip Jermann, and Jarret I Glasscock

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Whole-exome analysis of adolescents with low VWF and heavy menstrual bleeding identifies novel genetic associations, Brooke Sadler, Christina A Gurnett, Jorge Di Paola, and et al

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Bicyclic azetidines target acute and chronic stages of Toxoplasma gondii by inhibiting parasite phenylalanyl t-RNA synthetase, Joshua B Radke, Bruno Melillo, Payal Mittal, Manmohan Sharma, Amit Sharma, Yong Fu, Taher Uddin, Arthur Gonse, Eamon Comer, Stuart L Schreiber, Anil K Gupta, Arnab K Chatterjee, and L David Sibley