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Submissions from 2020

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The AT(N) framework for Alzheimer's disease in adults with Down syndrome, Michael S Rafii, Beau M Ances, and et al

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The Baby Bridge program: A sustainable program that can improve therapy service delivery for preterm infants following NICU discharge, Roberta Pineda, Elizabeth Heiny, Patricia Nellis, Joan Smith, Jaqueline M. McGrath, Margaux Collins, and Abigail Barker

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The cartilage matrisome in adolescent idiopathic scoliosis, Carol A. Wise, Diane Sepich, Aki Ushiki, Anas M. Khanshour, Yared H. Kidane, Nadja Makki, Christina A. Gurnett, Ryan S. Gray, Jonathan J. Rios, Nadav Ahituv, and Lila Solnica-Krezel

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The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain, Jared V. Goodman, Tomoko Yamada, Yue Yang, Lingchun Kong, Dennis Y. Wu, Guoyan Zhao, Harrison W. Gabel, and Azad Bonni

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The clonal evolution of metastatic colorectal cancer, Ha X Dang, Bradley A Krasnick, Julie G Grossman, Matthew S Strand, Jin Zhang, Christopher A Miller, Robert S Fulton, S Peter Goedegebuure, Catrina C Fronick, Malachi Griffith, David E Larson, Brian D Goetz, Jason R Walker, William G Hawkins, Steven M Strasberg, Kian H Lim, Timothy J Ley, Christopher A Maher, Ryan C Fields, and et al

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The complex interactions between rotavirus and the gut microbiota, Andrew HyoungJin Kim, Michael P Hogarty, Vanessa C Harris, and Megan T Baldridge

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The current state of antifungal stewardship among pediatric antimicrobial stewardship programs, Lourdes Eguiguren, Jason G Newland, Matthew P Kronman, Adam L Hersh, Jeffrey S Gerber, Grace M Lee, and Hayden T Schwenk

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The current state of HIV and aging: Findings presented at the 10th International Workshop on HIV and Aging, Stephanie Shiau, Jane A. O'Halloran, and et al.

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The de-implementation and persistence of low-value HIV prevention interventions in the United States: A cross-sectional study, Virginia R McKay, Todd B Combs, M Margaret Dolcini, and Ross C Brownson

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The effect of smoking during pregnancy on severity and directionality of externalizing and internalizing symptoms: A genetically informed approach, Mikael O Ekblad, Kristine Marceau, Emily Rolan, Rohan H C Palmer, Alexandre Todorov, Andrew C Heath, and Valerie S Knopik

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The genetic architecture of human brainstem structures and their involvement in common brain disorders, Torbjørn Elvsåshagen, Deanna M. Barch, and et al.

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The genetic architecture of sporadic and multiple consecutive miscarriage, Triin Laisk, Avinash Ramu, Donald F. Conrad, and et al.

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The global and national burden of chronic kidney disease attributable to ambient fine particulate matter air pollution: A modelling study, Benjamin Bowe, Elena Artimovich, Yan Xie, Yan Yan, Miao Cai, and Ziyad Al-Aly

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The global and national burden of chronic kidney disease attributable to ambient fine particulate matter air pollution: A modelling study, Benjamin Bowe, Elena Artimovich, Yan Xie, Yan Yan, Miao Cai, and Ziyad Al-Aly

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The gut microbiome defines social group membership in honey bee colonies, Cassondra L Vernier, Iris M Chin, Boahemaa Adu-Oppong, Joshua J Krupp, Joel Levine, Gautam Dantas, and Yehuda Ben-Shahar

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The herbivore's dilemma: Trends in and factors associated with heterosexual relationship status and interest in romantic relationships among young adults in Japan-Analysis of national surveys, 1987-2015, Cyrus Ghaznavi, Haruka Sakamoto, Shuhei Nomura, Anna Kubota, Daisuke Yoneoka, Kenji Shibuya, and Peter Ueda

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The immunologic effect of early intravenous two and four gram bolus dosing of tranexamic acid compared to placebo in patients with severe traumatic bleeding (TAMPITI): A randomized, double-blind, placebo-controlled, single-center trial, Philip C Spinella, Kimberly A Thomas, Isaiah R Turnbull, Anja Fuchs, Kelly Bochicchio, Douglas Schuerer, Stacey Reese, Adrian A Coleoglou Centeno, Christopher B Horn, Jack Baty, Susan M Shea, M Adam Meledeo, Anthony E Pusateri, Jerrold H Levy, Andrew P Cap, Grant V Bochicchio, and TAMPITI Investigators

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The impact of SARS-CoV-2 in dementia across Latin America: A call for an urgent regional plan and coordinated response, Agustin Ibanez, Jorge Llibre-Guerra, and et al

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The landscape of novel therapeutics and challenges in glioblastoma multiforme: Contemporary state and future directions, Karam Khaddour, Tanner M Johanns, and George Ansstas

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The long-term effects of a family based economic empowerment intervention (Suubi+Adherence) on suppression of HIV viral loads among adolescents living with HIV in southern Uganda: Findings from 5-year cluster randomized trial, Fred M. Ssewamala, Darejan Dvalishvili, Claude A. Mellins, Elvin H. Geng, Fredderick Makumbi, Torsten B. Neilands, Mary McKay, Christopher Damulira, Proscovia Nabunya, Ozge Sensoy Bahar, Gertrude Nakigozi, Godfrey Kigozi, William Byansi, Miriam Mukasa, and Flavia Namuwonge

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The membrane-associated form of cyclin D1 enhances cellular invasion, Ke Chen, Xuanmao Jiao, Anthony Ashton, Agnese Di Rocco, Timothy G. Pestell, Yunguang Sun, Jun Zhao, Mathew C. Casimiro, Zhiping Li, Michael P. Lisanti, Peter A. McCue, Duanwen Shen, Samuel Achilefu, Hallgeir Rui, and Richard G. Pestell

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The MYCL and MXD1 transcription factors regulate the fitness of murine dendritic cells, David A. Anderson III, Theresa L. Murphy, Robert N. Eisenman, and Kenneth M. Murphy

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The MYCL and MXD1 transcription factors regulate the fitness of murine dendritic cells, David A. Anderson III, Theresa L. Murphy, Robert N. Eisenman, and Kenneth M. Murphy

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The NEMP family supports metazoan fertility and nuclear envelope stiffness, Yonit Tsatskis, Ariz Mohammad, Karen Krchma, Jun Wu, Didier Hodzic, Daniel Potter, Tim Schedl, Kyunghee Choi, Helen McNeill, and et al

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The non-coding RNA landscape of plasma cell dyscrasias, Eugenio Morelli, Roberta Rocca, Kareem A Azab, and et al

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The pathway to secondary prevention of Alzheimer's disease, Eric McDade, Martin M Bednar, H Robert Brashear, David S Miller, Paul Maruff, Christopher Randolph, Zahinoor Ismail, Maria C Carrillo, Christopher J Weber, Lisa J Bain, and Ann Marie Hake

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The Prescription Opioids and Depression Pathways cohort study, Jeffrey F Scherrer, Brian Ahmedani, Kirsti Autio, Lynn Debar, Patrick J Lustman, Lisa R Miller-Matero, Joanne Salas, Scott Secrest, Mark D Sullivan, Lauren Wilson, and Sarah Skiold-Hanlin

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The price of the ticket: Health costs of upward mobility among African Americans, Darrell Hudson, Tina Sacks, Katie Irani, and Antonia Asher

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The probable, possible, and novel functions of ERp29, Margaret Brecker, Svetlana Khakhina, Tyler J Schubert, Zachary Thompson, and Ronald C Rubenstein

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Therapeutic enhancement of blood-brain and blood-tumor barriers permeability by laser interstitial thermal therapy, Afshin Salehi, Mounica R Paturu, Bhuvic Patel, Matthew D Cain, Tatenda Mahlokozera, Alicia B Yang, Tsen-Hsuan Lin, Eric C Leuthardt, Hiroko Yano, Sheng-Kwei Song, Robyn S Klein, Robert Schmidt, and Albert H Kim

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Therapies for tuberculosis and AIDS: Myeloid-derived suppressor cells in focus, Anca Dorhoi, Shabaana A Khader, and et al

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The relation between personality and biomarkers in sensitivity and conversion to Alzheimer-type dementia, Janet M Duchek, Andrew J Aschenbrenner, Anne M Fagan, Tammie L S Benzinger, John C Morris, and David A Balota

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The road to recovery: A pilot study of driving behaviors following antibody-mediated encephalitis, Gregory S. Day, Ganesh M. Babulal, Ganesh Rajasekar, Sarah Stout, and Catherine M. Roe

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The role of CT-quantified body composition on longitudinal health-related quality of life in colorectal cancer patients: The Colocare Study, Biljana Gigic, Graham A Colditz, Adetunji T Toriola, and et al

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The role of eye tracking technology in assessing older driver safety, David B Carr and Prateek Grover

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The role of human milk oligosaccharides and probiotics on the neonatal microbiome and risk of necrotizing enterocolitis: A narrative review, Lila S Nolan, Jamie M Rimer, and Misty Good

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The tethering function of mitofusin2 controls osteoclast differentiation by modulating the Ca2+–NFATc1 axis, Anna Ballard, Rong Zeng, Allahdad Zarei, Christine Shao, Linda Cox, Hui Yan, Antonietta Franco, Gerald W. Dorn II, Roberta Faccio, and Deborah J. Veis

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The transcription factor EB reduces the intraneuronal accumulation of the beta-secretase-derived APP fragment C99 in cellular and mouse Alzheimer’s disease models, Anaïs Bécot, Raphaëlle Pardossi-Piquard, Alexandre Bourgeois, Eric Duplan, Qingli Xiao, Abhinav Diwan, Jin-Moo Lee, Inger Lauritzen, and Frédéric Checler

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The validity and reliability of the Microsoft Kinect for measuring trunk compensation during reaching, Matthew H Foreman and Jack R Engsberg

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TicTimer Web: Software for measuring tic suppression remotely, Jonathan K Black, Jonathan M Koller, and Kevin J. Black

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Time-series cardiovascular risk factors and receipt of screening for breast, cervical, and colon cancer: The Guideline Advantage, Aixia Guo, Bettina F. Drake, Yosef M. Khan, James R. Langabeer II, and Randi E. Foraker

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To “heed the call” amidst the COVID-19 pandemic, Andrew W. Kuhn, Francesca R. Coxe, Kyle N. Kunze, and David N. Bernstein

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Top ten tips palliative care clinicians should know about amyotrophic lateral sclerosis, Elyse A. Everett, Elizabeth Pedowitz, Samuel Maiser, Joss Cohen, Jessica Besbris, Ambereen K. Mehta, Luqi Chi, and Christopher A. Jones

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Tourette syndrome research highlights from 2019, Andreas Hartmann, Yulia Worbe, and Kevin J Black

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Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells, Koji Matsuhisa, Longjie Cai, Atsushi Saito, Fumika Sakaue, Yasunao Kamikawa, Sachiko Fujiwara, Rie Asada, Yukitsuka Kudo, and Kazunori Imaizumi

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TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML, Jayakumar Vadakekolathu, Michael P. Rettig, John F. DiPersio, and et al.

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TPL2 enforces RAS-induced inflammatory signaling and is activated by point mutations, Paarth B Dodhiawala, Namrata Khurana, Daoxiang Zhang, Yi Cheng, Lin Li, Qing Wei, Kuljeet Seehra, Hongmei Jiang, Patrick M Grierson, Andrea Wang-Gillam, and Kian-Huat Lim

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Tracking regional brain growth up to age 13 in children born term and very preterm, Deanne K. Thompson, Lilian G. Matthews, Bonnie Alexander, Katherine J. Lee, Claire E. Kelly, Chris L. Adamson, Rod W. Hunt, Jeanie L.Y. Cheong, Megan Spencer-Smith, Jeffrey J. Neil, Marc L. Seal, Terrie E. Inder, Lex W. Doyle, and Peter J. Anderson

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Transcriptome analysis of alternative splicing in the pathogen life cycle in human foreskin fibroblasts infected with Trypanosoma cruzi, Hyeim Jung, Seonggyun Han, and Younghee Lee

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Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma, Kelly Regan-Fendt, Ding Li, Ryan Reyes, Lianbo Yu, Nissar A Wani, Peng Hu, Samson T Jacob, Kalpana Ghoshal, Philip R O Payne, and Tasneem Motiwala

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Treatment-emergent neuroendocrine prostate cancer: A clinicopathological and immunohistochemical analysis of 94 cases, Qingfu Zhang, Yunan Han, Yao Zhang, Dan Liu, Jian Ming, Bo Huang, and Xueshan Qiu

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Trends in Diagnosis Related Groups for inpatient admissions and associated changes in payment from 2012 to 2016, Ty J. Gluckman, Kateri J. Spinelli, Mansen Wang, Amir Yazdani, Gary Grunkemeier, Steven M. Bradley, Jason H. Wasfy, Abhinav Goyal, Andrew Oseran, and Karen E. Joynt Maddox

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Trends in postrelapse survival in classic Hodgkin lymphoma patients after experiencing therapy failure following auto-HCT, Talha Badar, Narendranath Epperla, Aniko Szabo, Steven Borson, John Vaughn, Gemlyn George, Neeraj Saini, Abdul Rashid Shah, Romil D. Patel, Sairah Ahmed, Nirav N. Shah, Amanda F. Cashen, Mehdi Hamadani, and Timothy S. Fenske

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Trial of sodium phenylbutyrate–taurursodiol for amyotrophic lateral sclerosis, Sabrina Paganoni, Timothy M. Miller, and et al

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Tumor-associated macrophages in osteosarcoma: From mechanisms to therapy, Francesca Cersosimo, Silvia Lonardi, Giulia Bernardini, Brian Telfer, Giulio Eugenio Mandelli, Annalisa Santucci, William Vermi, and Emanuele Giurisato

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Tumor burden, inflammation, and product attributes determine outcomes of axicabtagene ciloleucel in large B-cell lymphoma, Frederick L. Locke, Armin Ghobadi, and et al.

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Tumor infiltrating neutrophils are enriched in basal-type urothelial bladder cancer, Giulio Eugenio Mandelli, Francesco Missale, Debora Bresciani, Luisa Benerini Gatta, Patrizia Scapini, Elena Caveggion, Elisa Roca, Mattia Bugatti, Matilde Monti, Luca Cristinelli, Sandra Belotti, Claudio Simeone, Stefano Calza, Laura Melocchi, and William Vermi

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Tumor microenvironment as a regulator of radiation therapy: New insights into stromal-mediated radioresistance, Varintra E Krisnawan, Jennifer A Stanley, Julie K Schwarz, and David G DeNardo

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Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma, Cinzia Federico, Kinan Alhallak, Jennifer Sun, Kathleen Duncan, Feda Azab, Gail P. Sudlow, Pilar de la Puente, Barbara Muz, Vaishali Kapoor, Luna Zhang, Fangzheng Yuan, Matea Markovic, Joseph Kotsybar, Katherine Wasden, Nicole Guenthner, Shannon Gurley, Justin King, Daniel Kohnen, Noha N. Salama, Dinesh Thotala, Dennis E. Hallahan, Ravi Vij, John F. DiPersio, Samuel Achilefu, and Abdel Kareem Azab

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Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation, Panpan Hou, Po Wei Kang, Audrey Deyawe Kongmeneck, Nien-Du Yang, Yongfeng Liu, Jingyi Shi, Xianjin Xu, Kelli McFarland White, Mark A. Zaydman, Marina A. Kasimova, Guiscard Seebohm, Ling Zhong, Xiaoqin Zou, Mounir Tarek, and Jianmin Cui

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Uncovering tumour heterogeneity through PKR and nc886 analysis in metastatic colon cancer patients treated with 5-FU-based chemotherapy, María Belén Ortega-García, Igor Zwir, and et al

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Understanding antibiotic prophylaxis prescribing in pediatric surgical specialties, Sara M Malone, Natalie S Seigel, Jason G Newland, Jacqueline M Saito, and Virginia R McKay

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Understanding patient transfers across multiple clinics in Zambia among HIV infected adults, Kombatende Sikombe, Aaloke Mody, Jillian Kadota, Jesse Jake Pry, Sandra Simbeza, Ingrid Eshun-Wilson, Sitali Richard Situmbeko, Chama Bukankala, Laura Beres, Njekwa Mukamba, Mwanza Wa Mwanza, Carolyn Bolton-Moore, Charles B. Holmes, Elvin H. Geng, and Izukanji Sikazwe

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Unique growth pathway in solution−solid−solid nanowires: Cubic to hexagonal phase transformation, Yi-Hsin Liu, Ho-Ying Chen, Hsiu-Fang Fan, Yu-Hsien Chen, and Fudong Wang

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Unmasking intra-tumoral heterogeneity and clonal evolution in NF1-MPNST, Chang-In Moon, William Tompkins, Yuxi Wang, Abigail Godec, Xiaochun Zhang, Patrik Pipkorn, Christopher A Miller, Carina Dehner, Sonika Dahiya, and Angela C Hirbe

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Updated perspectives on the management of multiple myeloma in older patients: Focus on lenalidomide, Kelly L Schoenbeck and Tanya M Wildes

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Upregulation of 5′‑terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor, Kyle A. Cottrell, Ryan C. Chiou, and Jason D. Weber

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Use of ICD-10 codes for identification of injection drug use-associated infective endocarditis is nonspecific and obscures critical findings on impact of medications for opioid use disorder, Laura R. Marks, Nathanial S. Nolan, Linda Jiang, Dharushana Muthulingam, Stephen Y. Liang, and Michael J. Durkin

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Use of neuroimaging to inform optimal neurocognitive criteria for detecting HIV-associated brain abnormalities, Laura M Campbell, David B Clifford, et al, and CHARTER Group

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Use of the theory of planned behavior framework to understand breastfeeding decision-making among mothers of preterm infants, Margaret G. Parker, Sunah S. Hwang, Emma S. Forbes, Bryanne N. Colvin, Kyria R. Brown, and Eve R. Colson

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Using a developmental perspective to examine the moderating effects of marriage on heavy episodic drinking in a young adult sample enriched for risk, Seung Bin Cho, Rebecca L Smith, Kathleen Bucholz, Grace Chan, Howard J Edenberg, Victor Hesselbrock, John Kramer, Vivia V McCutcheon, John Nurnberger, Marc Schuckit, Yong Zang, Danielle M Dick, and Jessica E Salvatore

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Using a sociogram to characterize communication during an interprofessional team huddle, Lisa Royse, Nathanial Nolan, and Kimberly Hoffman

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Using digital technology to reduce the prevalence of mental health disorders in populations: Time for a new approach, C Barr Taylor, Josef I Ruzek, Ellen E Fitzsimmons-Craft, Shiri Sadeh-Sharvit, Naira Topooco, Ruth Striegel Weissman, Daniel Eisenberg, David Mohr, Andrea Graham, Corinna Jacobi, and Brian Oldenburg

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Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples, Peter B. Barr, Emma C. Johnson, Andrey Anokhin, Arpana Agrawal, and et al.

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Using practice effects for targeted trials or sub-group analysis in Alzheimer's disease: How practice effects predict change over time, Guoqiao Wang, Richard E. Kennedy, Terry E. Goldberg, Mackenzie E. Fowler, Gary R. Cutter, and Lon S. Schneider

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Using the Systemic Immune-Inflammation Index (SII) as a mid-treatment marker for survival among patients with stage-III locally advanced non-small cell lung cancer (NSCLC), Tithi Biswas, Kylie H Kang, Rohin Gawdi, David Bajor, Mitchell Machtay, Charu Jindal, and Jimmy T Efird

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Using the zebrafish lateral line to understand the roles of mitochondria in sensorineural hearing loss, Melanie Holmgren and Lavinia Sheets

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Uterine natural killer cell heterogeneity: Lessons from mouse models, Dorothy K Sojka

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Utilization of the Sharing Antimicrobial Reports for Pediatric Stewardship (SHARPS) Collaborative electronic mailing list (listserv) by healthcare professionals, Christopher C McPherson, Zachary A Vesoulis, Talene A Metjian, Mirela Grabic, Summer Reyes, Sydney Reyes, Christina Krucylak, Cindy Terrill, and Jason G Newland

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Validation of a Parkinson disease predictive model in a population-based study, Irene M. Faust, Brad A. Racette, and Susan Searles Nielsen

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Validity of smartphone heart rate variability pre- and post-resistance exercise, Clifton J. Holmes, Michael V Fedewa, Lee J Winchester, Hayley V MacDonald, Stefanie A Wind, and Michael R Esco

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Viral-immune cell interactions at the maternal-fetal interface in human pregnancy, Elaine L Parker, Rachel B Silverstein, Sonam Verma, and Indira U Mysorekar

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Visible-light promoted atom transfer radical addition-elimination (ATRE) reaction for the synthesis of fluoroalkylated alkenes using DMA as electron-donor, Wen-Wen Xu, Le Wang, Ting Mao, Jiwei Gu, Xiao-Fei Li, and Chun-Yang He

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Vitamin D receptor protects against dysbiosis and tumorigenesis via the JAK/STAT pathway in intestine, Yong-Guo Zhang, Rong Lu, Shaoping Wu, Ishita Chatterjee, David Zhou, Yinglin Xia, and Jun Sun

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When (almost) everyone is above average: A critical analysis of American Orthopaedic Association Committee of Residency Directors standardized letters of recommendation, Paul M. Inclan, Alisa A. Cooperstein, Alexa Powers, Christopher J. Dy, and Sandra E. Klein

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When STING meets viruses: Sensing, trafficking and response, Zhaohe Li, Siqi Cai, Yutong Sun, Li Li, Siyuan Ding, and Xin Wang

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Who benefits from a prostate rectal spacer? Secondary analysis of a phase III trial, Thomas J. Quinn, Walter Bosch, and et al.

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Wikidata as a knowledge graph for the life sciences, Andra Waagmeester, Malachi Griffith, Obi L. Griffith, and et al.

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Wirelessly controlled, bioresorbable drug delivery device with active valves that exploit electrochemically triggered crevice corrosion, Jahyun Koo, Jawad Khalifeh, Ying Yan, Wilson Z Ray, Matthew MacEwan, and et al

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Work-related and personal factors associated with mental well-being during the COVID-19 response: Survey of health care and other workers, Bradley A Evanoff, Jaime R Strickland, Ann Marie Dale, Lisa Hayibor, Emily Page, Jennifer G Duncan, Thomas Kannampallil, and Diana L Gray

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Workshop on the development and evaluation of digital therapeutics for health behavior change: Science, methods, and projects, Alan J Budney, Lisa A Marsch, Will M Aklin, Jacob T Borodovsky, Mary F Brunette, Andrew T Campbell, Jesse Dallery, David Kotz, Ashley A Knapp, Sarah E Lord, Edward V Nunes, Emily A Scherer, Catherine Stanger, and William C Torrey

Submissions from 2019

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Noninvasive detection of graft injury after heart transplant using donor-derived cell-free DNA: A prospective multicenter study, Kiran K Khush, Jignesh Patel, Sean Pinney, Andrew Kao, Rami Alharethi, Eugene DePasquale, Gregory Ewald, Peter Berman, Manreet Kanwar, David Hiller, James P Yee, Robert N Woodward, Shelley Hall, and Jon Kobashigawa

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B cell-mediated antigen presentation through MHC class II is dispensable for atherosclerosis progression, Jesse W Williams, Andrew Elvington, Skyler Kessler, Mary Wohltmann, Gregory F Wu, and Gwendalyn J Randolph

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Protocol for the ElectroeNcephalography Guidance of Anesthesia to alleviate GEriatric Syndromes (ENGAGES-Canada) study: A pragmatic, randomized clinical trial, Alain Deschamps, Jordan Oberhaus, Angela Mickle, Arbi Ben Abdallah, Michael S Avidan, and et al.