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Submissions from 2020

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Challenges and solutions for the implementation of shared decision-making in breast reconstruction, Terence M. Myckatyn, Rajiv P. Parikh, Clara Lee, and Mary C. Politi

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Change in age at diagnosis of oropharyngeal cancer in the United States, 1975-2016, Brittany J Cline, Matthew C Simpson, Matthew Gropler, Aleksandr R Bukatko, Eric Adjei Boakye, Kahee A Mohammed, and Nosayaba Osazuwa-Peters

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Characteristics and outcomes among a hospitalized patient cohort with Streptococcus pneumoniae infection, Scott T. Micek, James Simmons, Nicholas Hampton, and Marin H. Kollef

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Characterization of a high-resolution breath acetone meter for ketosis monitoring, Donald J Suntrup Iii, Timothy V Ratto, Matt Ratto, and James P McCarter

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Characterization of missense mutations in the signal peptide and propeptide of FIX in hemophilia B by a cell-based assay, Wenwen Gao, Yaqi Xu, Hongli Liu, Meng Gao, Qing Cao, Yiyi Wang, Longteng Cui, Rong Huang, Yan Shen, Sanqiang Li, Haiping Yang, Yixiang Chen, Chaokun Li, Haichuan Yu, Weikai Li, and Guomin Shen

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Characterization of radiotherapy component impact on MR imaging quality for an MRgRT system, Benjamin C Lewis, Bruce Gu, Ryan Klett, Rajiv Lotey, Olga L Green, and Taeho Kim

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Characterization of the complete mitochondrial genomes of two sibling species of parasitic roundworms, Haemonchus contortus and Teladorsagia circumcincta, Nikola Palevich, Paul H Maclean, Young-Jun Choi, and Makedonka Mitreva

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Chemical effects of diceCT staining protocols on fluid-preserved avian specimens, Catherine M. Early, Ashley C. Morhardt, Timothy P. Cleland, Christopher M. Milensky, Gwénaëlle M. Kavich, and Helen F. James

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Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita, Siddharth Shukla, Ho-Chang Jeong, Christopher M. Sturgeon, Roy Parker, and Luis Francisco Zirnberger Batista

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Chemical mutagenesis of a GPCR ligand: Detoxifying “inflammo-attraction” to direct therapeutic stem cell migration, Jean-Pyo Lee, Edward B. Han, and et al.

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Chikungunya virus strains from each genetic clade bind sulfated glycosaminoglycans as attachment factors, Nicole McAllister, Michael S. Diamond, and et al

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Chimerism in the realm of hematopoietic stem cell transplantation for non-malignant disorders-A perspective, Clare Zimmerman and Shalini Shenoy

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Chloroquine triggers cell death and inhibits PARPs in cell models of aggressive hepatoblastoma, Katja Eloranta, Stefano Cairo, Emmi Liljeström, Tea Soini, Antti Kyrönlahti, Jean-Gabriel Judde, David B Wilson, Markku Heikinheimo, and Marjut Pihlajoki

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Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion, Ruochen Zang, James Brett Case, Xiucui Ma, Maria Florencia Gomez Castro, Zhuoming Liu, Qiru Zeng, Haiyan Zhao, Juhee Son, Paul W. Rothlauf, Gaopeng Hou, Michael D. Vahey, Kartik Mani, Daved H. Fremont, Abhinav Diwan, Michael S. Diamond, Sean P.J. Whelan, Siyuan Ding, and et al.

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Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy, Roxana O Carare, David Holtzman, and et al

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Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain, Melanie Y. Pullen, Conrad C. Weihl, and Heather L. True

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Clinical and functional significance of circular RNAs in cytogenetically normal AML, Dimitrios Papaioannou, Geoffrey L. Uy, and et al.

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Clinical experience of MRI4D QUASAR motion phantom for latency measurements in 0.35T MR‐LINAC, Taeho Kim, Benjamin Lewis, Rajiv Lotey, Enzo Barberi, and Olga Green

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Clinical implications of restrictions in criteria for defining surgical site infections after mastectomy, Antoinette A A Bediako-Bowan, David K Warren, Katelin B Nickel, Victoria J Fraser, and Margaret A Olsen

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CNS microRNA profles: A database for cell type enriched microRNA expression across the mouse central nervous system, Nathan Pomper, Yating Liu, Mariah L. Hoye, Joseph D. Dougherty, and Timothy M. Miller

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Cockayne Syndrome: The many challenges and approaches to understand a multifaceted disease, Alexandre Teixeira Vessoni, Camila Chaves Coelho Guerra, Gustavo Satoru Kajitani, Livia Luz Souza Nascimento, and Camila Carrião Machado Garcia

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Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801, Guido Marcucci, Geoffrey L. Uy, and et al.

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Combined abdominal heterotopic heart and aorta transplant model in mice, Hao Dun, Li Ye, Yuehui Zhu, and Brian W Wong

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Come together: Protein assemblies, aggregates and the sarcostat at the heart of cardiac myocyte homeostasis, Moydul Islam, Abhinav Diwan, and Kartik Mani

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Community health behaviors and geographic variation in early-onset colorectal cancer survival among women, Andreana N. Holowatyj, Marvin E. Langston, Yunan Han, Richard Viskochil, Jose Perea, Yin Cao, Charles R. Rogers, Christopher H. Lieu, and Justin X. Moore

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Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease, Hemanth R. Nelvagal, Maica Llavero Hurtado, Samantha L. Eaton, Rachel A. Kline, Douglas J. Lamont, Mark S. Sands, Thomas M. Wishart, and Jonathan D. Cooper

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Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease, Aylin Dincer, Brian A Gordon, Sarah J Keefe, Shaney Flores, Nicole S McKay, Angela M Paulick, Rebecca L Feldman, Russ C Hornbeck, Beau M Ances, Nelly Joseph-Mathurin, Celeste M Karch, Eric M McDade, Richard J Perrin, Cyrus Raji, Qing Wang, Chengjie Xiong, John C Morris, Randall J Bateman, Tammie L S Benzinger, and et al

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Comparing transplant outcomes in ALL patients after haploidentical with PTCy or matched unrelated donor transplantation, Monzr M. Al Malki, Francesca Ferraro, Armin Ghobadi, and et al.

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Comparison of differential accessibility analysis strategies for ATAC-seq data, Paul Gontarz, Shuhua Fu, Xiaoyun Xing, Shaopeng Liu, Benpeng Miao, Viktoriia Bazylianska, Akhil Sharma, Pamela Madden, Kitra Cates, Andrew Yoo, Anna Moszczynska, Ting Wang, and Bo Zhang

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Comparison of smartphone photography, single-lens reflex photography, and field-grading for trachoma, John M Nesemann, Michael I Seider, Blake M Snyder, Robi N Maamari, Daniel A Fletcher, Berhan A Haile, Zerihun Tadesse, Nicole E Varnado, Sun Y Cotter, Elizabeth Kelly Callahan, Paul M Emerson, Todd P Margolis, Thomas M Lietman, and Jeremy D Keenan

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Comparison of the Ekblom-Bak submaximal test to a maximal test in a cohort of healthy younger and older adults in the United States, Stephanie A Schultz, Jennifer Byers, Tammie L S Benzinger, Dominic Reeds, Andrei G Vlassenko, W Todd Cade, and Manu S Goyal

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Comparison of three magnetization transfer ratio parameters for assessment of intestinal fibrosis in patients with Crohn’s disease, Jixin Meng, Siyun Huang, CanHui Sun, Zhong-wei Zhang, Ren Mao, Yan-hong Yang, Shi-Ting Feng, Zi-ping Li, and XueHua Li

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Competitive tight-binding inhibition of VKORC1 underlies warfarin dosage variation and antidotal efficacy, Shuang Li, Shixuan Liu, Xiaoran Roger Liu, Mengru Mira Zhang, and Weikai Li

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Complications and patient-reported outcomes after TRAM and DIEP flaps: A systematic review and meta-analysis, Waverly Y. He, Leen El Eter, Pooja Yesantharao, Bethany Hung, Haley Owens, Sarah Persing, and Justin M. Sacks

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Composite measure of physiological dysregulation as a predictor of mortality: The Long Life Family Study, Konstantin G Arbeev, Olivia Bagley, Svetlana V Ukraintseva, Hongzhe Duan, Alexander M Kulminski, Eric Stallard, Deqing Wu, Kaare Christensen, Mary F Feitosa, Bharat Thyagarajan, Joseph M Zmuda, and Anatoliy I Yashin

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Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease, Thomas A. Ray, Martha A. Cady, William J. Spencer, Philip A. Ruzycki, Brian S. Clark, and et al.

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Comprehensive profiling of extracellular RNA in HPV‑induced cancers using an improved pipeline for small RNA‑seq analysis, Fangjia Tong, Arlise Andress, Gongyu Tang, Ping Liu, and Xiaowei Wang

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Comprehensive validation of halcyon 2.0 plans and the implementation of patient specific QA with multiple detector platforms, Eric Laugeman, Ana Heermann, Jessica Hilliard, Michael Watts, Marshia Roberson, Robert Morris, Sreekrishna Goddu, Abhishek Sethi, Imran Zoberi, Hyun Kim, Sasa Mutic, Geoffrey Hugo, and Bin Cai

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Concern of photosensitive seizures evoked by 3D video displays or virtual reality headsets in children: Current perspective, Lawrence Tychsen and Liu Lin Thio

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Confidential genetic testing and electronic health records: A survey of current practices among Huntington disease testing centers, Celeste C Eno, Stacey K Barton, Naghmeh Dorrani, Stephen D Cederbaum, Joshua L Deignan, and Wayne W Grody

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Considerations in preparative regimen selection to minimize rejection in pediatric hematopoietic transplantation in non-malignant diseases, Robert J Hayashi

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Consumptive coagulopathy of severe yellow fever occurs independently of hepatocellular tropism and massive hepatic injury, Adam L. Bailey, Liang-I Kang, Luiz Gonzaga Francisco de Assis Barros D'Elia Zanella, Cássia G. T. Silveira, Yeh-Li Ho, Lander Foquet, Greg Bial, Broc T. McCune, Amaro Nunes Duarte-Neto, Archana Thomas, Hans-Peter Raué, Kathleen Byrnes, Esper G. Kallas, Mark K. Slifka, and Michael S. Diamond

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Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface, Matthias Garten, Josh R. Beck, Robyn Roth, Tatyana Tenkova-Heuser, John Heuser, Eva S. Istvan, Christopher K.E. Bleck, Daniel E. Goldberg, and Joshua Zimmerberg

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Context Is key: Delineating the unique functions of IFNα and IFNβ in disease, Lindsey E Fox, Marissa C Locke, and Deborah J Lenschow

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Contraception provision in the emergency department: Are we ready to overcome the obstacles?, Kayleigh Fischer and Lauren S. Chernick

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Contribution of aberrant Toll like receptor signaling to the pathogenesis of myelodysplastic syndromes, Luana Chiquetto Paracatu and Laura G Schuettpelz

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Contribution of immune cells to glucocorticoid receptor expression in breast cancer, Shipra Gandhi, Ahmed Elkhanany, Masanori Oshi, Tao Dai, Mateusz Opyrchal, Hemn Mohammadpour, Elizabeth A Repasky, and Kazuaki Takabe

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Converging on bladder health through design thinking: From an ecology of influence to a focused set of research questions, Jessica B Lewis, Sonya S Brady, Siobhan Sutcliffe, Ariana L Smith, Elizabeth R Mueller, Kyle Rudser, Alayne D Markland, Ann Stapleton, Sheila Gahagan, Shayna D Cunningham, and Prevention Of Lower Urinary Tract Symptoms Plus Research Consortium

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Co-occurrence of Campylobacter species in children from eastern Ethiopia, and their association with environmental enteric dysfunction, diarrhea, and host microbiome, Yitagele Terefe, Mark J Manary, Maria Isabel Ordiz, and et al

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Core warming of coronavirus disease 2019 (COVID-19) patients undergoing mechanical ventilation-A protocol for a randomized controlled pilot study, Nathaniel Bonfanti, Emily Gundert, Anne M. Drewry, Kristina Goff, Roger Bedimo, and Erik Kulstad

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Coronavirus proteins as ion channels: Current and potential research, Conor McClenaghan, Alex Hanson, Sun-Joo Lee, and Colin G Nichols

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Critical response to ab interno versus ab externo surgical approach on outflow resistance of a subconjunctival drainage device, Arsham Sheybani, Davinder S. Grover, and Ronald L. Fellman

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Cryo-EM structures of the air-oxidized and dithionite-reduced photosynthetic alternative complex III from Roseiflexus castenholzii, Yang Shi, Yueyong Xin, Chao Wang, Robert E Blankenship, Fei Sun, and Xiaoling Xu

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Cryptococcus neoformans evades pulmonary immunity by modulating xylose precursor transport, Lucy X. Li, Camaron R. Hole, Javier Rangel-Moreno, Shabaana A. Khader, and Tamara L. Doering

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Dangerous liaisons: Interactions of Cryptococcus neoformans with host phagocytes, Elizabeth A Gaylord, Hau Lam Choy, and Tamara L Doering

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Deciphering the factors that influence participation in studies requiring serial lumbar punctures, Gregory S Day, Tracy Rappai, Sushila Sathyan, and John C Morris

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Deciphering the role of innate immune NF-ĸB pathway in pancreatic cancer, Namrata Khurana, Paarth B Dodhiawala, Ashenafi Bulle, and Kian-Huat Lim

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Deconstructing tumor heterogeneity: The stromal perspective, Renee E. Vickman, Douglas V. Faget, Sheila A. Stewart, and et al

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Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity, Vincenza Cifarelli, Scott C Beeman, Gordon I Smith, Jun Yoshino, Darya Morozov, Joseph W Beals, Brandon D Kayser, Jeramie D Watrous, Mohit Jain, Bruce W Patterson, and Samuel Klein

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Deep brain stimulation of the subthalamic nucleus modulates reward-related behavior: A systematic review, Yvan M Vachez and Meaghan C Creed

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DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods, Yu He, Hyo Sik Jang, Xiaoyun Xing, Daofeng Li, Michael J Vasek, Joseph D Dougherty, and Ting Wang

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Deep learning assessment of breast terminal duct lobular unit involution: Towards automated prediction of breast cancer risk, Suzanne C. Wetstein, Ying Liu, and et al.

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Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm, Se-Jin Jeong, Min Ji Cho, Na Young Ko, Sinai Kim, In-Hyuk Jung, Jeong-Ki Min, Sang Hak Lee, Jong-Gil Park, and Goo Taeg Oh

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Defining and conceptualizing outcomes for de-implementation: Key distinctions from implementation outcomes, Beth Prusaczyk, Taren Swindle, and Geoffrey Curran

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Dementia research in the Caribbean Hispanic islands: Present findings and future trends, Daisy Acosta, Jorge J Llibre-Guerra, Ivonne Z Jiménez-Velázquez, and Juan J Llibre-Rodríguez

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Dendritic and parallel processing of visual threats in the retina control defensive responses, T Kim, N Shen, J-C Hsiang, K P Johnson, and D Kerschensteiner

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Depletion interactions modulate the binding between disordered proteins in crowded environments, Franziska Zosel, Andrea Soranno, Karin J. Buholzer, Daniel Nettels, and Benjamin Schuler

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Deployment of convalescent plasma for the prevention and treatment of COVID-19, Evan M Bloch, Brenda J Grossman, Jeffrey P Henderson, and et al

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Depression and nicotine withdrawal associations with combustible and electronic cigarette use, Michele L Pergadia, John W Newcomer, and David G Gilbert

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Depressogenic self-schemas are associated with smaller regional grey matter volume in never-depressed preadolescents, Pan Liu, Matthew R J Vandemeer, Marc F Joanisse, Deanna M Barch, David J A Dozois, and Elizabeth P Hayden

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Design and rationale of the HAPIN study: A multicountry randomized controlled trial to assess the effect of liquefied petroleum gas stove and continuous fuel distribution, Thomas Clasen, Victor G. Davila-Roman, and et al.

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Detecting pneumonia using convolutions and dynamic capsule routing for chest X-ray images, Ansh Mittal, Deepika Kumar, Mamta Mittal, Tanzila Saba, Ibrahim Abunadi, Amjad Rehman, and Sudipta Roy

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Determinants of mammographic breast density by race among a large screening population, Justin X. Moore, Yunan Han, Catherine Appleton, Graham Colditz, and Adetunji T. Toriola

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Determining the recommended dose of pacritinib: Results from the PAC203 dose-finding trial in advanced myelofibrosis, Aaron T. Gerds, Stephen T. Oh, and et al.

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Development and evaluation of a computerized clinical outcome assessment tool for head and neck cancer patients, Ching-Rong Lin, Kang-Hsing Fan, Chien-Yu Lin, Tsung-Min Hung, Bing-Shen Huang, Eric Yen-Chao Chen, Chung-Jan Kang, Shiang-Fu Huang, Joseph Tung-Chieh Chang, and Chih-Hung Chang

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Development and evaluation of machine learning models for voxel dose predictions in online adaptive magnetic resonance guided radiation therapy, M Allan Thomas, Yabo Fu, and Deshan Yang

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Development and validation of a rapid lateral flow E1/E2-antigen test and ELISA in patients infected with emerging Asian strain of Chikungunya virus in the Americas, Ankita Reddy, Michael S Diamond, and et al

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Development of a new macrophage-specifc TRAP mouse (MacTRAP) and definition of the renal macrophage translational signature, Andreas Hofmeister, Maximilian C. Thomaßen, Sabrina Markert, André Marquardt, Mathieu Preußner, Martin Rußwurm, Ralph T. Schermuly, Ulrich Steinhoff, Hermann-Josef Gröne, Joachim Hoyer, Benjamin D. Humphreys, and Ivica Grgic

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Development of aplastic anemia during treatment of anaplastic astrocytoma with temozolomide, Karam Khaddour, Nigel Harrison, Ashwin Govindan, and Jian L. Campian

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Development of volumetric independent dose calculation system for verification of the treatment plan in image-guided adaptive brachytherapy, Sang-Won Kang, Jin-Beom Chung, Kyeong-Hyeon Kim, Ji-Yeon Park, Hae-Jin Park, Woong Cho, Sven Olberg, Tae Suk Suh, and Justin C Park

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Diabetes minimally mediated the association between PM2.5 air pollution and kidney outcomes, Benjamin Bowe, Yan Xie, Yan Yan, Hong Xian, and Ziyad Al-Aly

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Dietary glycaemic index, glycaemic load and head and neck cancer risk: A pooled analysis in an international consortium, Chun-Pin Chang, Jose P Zevallos, and et al

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Diet-induced metabolic dysregulation in female mice causes osteopenia in adult offspring, Yu Shi, Jessica L. Saben, Guangxu He, Kelle H. Moley, and Fanxin Long

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Diet modifies pioglitazone’s influence on hepatic PPARγ-regulated mitochondrial gene expression, Sakil Kulkarni, Jiansheng Huang, Eric Tycksen, Paul F. Cliften, and David A. Rudnick

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Diet quality, food groups and nutrients associated with the gut microbiota in a nonwestern population, Ángela S García-Vega, Vanessa Corrales-Agudelo, Alejandro Reyes, and Juan S Escobar

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Differences in electronic personal health information tool use between rural and urban cancer patients in the United States: Secondary data analysis, Alexandra Greenberg-Worisek, Liaa Ferede, Joyce Balls-Berry, Ian Marigi, Emily Valentin Mendez, Numra Bajwa, Melody Ouk, Minerva Orellana, and Felicity Enders

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Differentiating among stages of cognitive impairment in aging: Version 3 of the Uniform Data Set (UDS) neuropsychological test battery and MoCA index scores, Hiroko H Dodge, John C Morris, and et al

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Diffusion basis spectrum imaging detects axonal loss after transient dexamethasone treatment in optic neuritis mice, Tsen-Hsuan Lin, Jie Zhan, Chunyu Song, Michael Wallendorf, Peng Sun, Xuan Niu, Ruimeng Yang, Anne H Cross, and Sheng-Kwei Song

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Digital translucence: Adapting telemedicine delivery post-COVID-19, Thomas Kannampallil and Jun Ma

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Dill extract induces elastic fiber neosynthesis and functional improvement in the ascending aorta of aged mice with reversal of age-dependent cardiac hypertrophy and involvement of lysyl oxidase-like-1, Wassim Fhayli, Quentin Boëté, Nadjib Kihal, Valérie Cenizo, Pascal Sommer, Walter A Boyle, Marie-Paule Jacob, and Gilles Faury

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Direct neuronal reprogramming of common marmoset fibroblasts by ASCL1, microRNA-9/9*, and microRNA-124 overexpression, Akisa Nemoto, Reona Kobayashi, Sho Yoshimatsu, Yuta Sato, Takahiro Kondo, Andrew S Yoo, Seiji Shiozawa, and Hideyuki Okano

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Direct tumor visual feedback during free breathing in 0.35T MRgRT, Taeho Kim, Benjamin C Lewis, Alex Price, Thomas Mazur, H Michael Gach, Justin C Park, Bin Cai, Erin Wittland, Lauren Henke, Hyun Kim, Sasa Mutic, and Olga Green

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Discovery of a novel simian pegivirus in common marmosets (Callithrix jacchus) with lymphocytic enterocolitis, Anna S. Heffron, Michael Lauck, Elizabeth D. Somsen, Elizabeth C. Townsend, Adam L. Bailey, Megan Sosa, Jens Eickhoff, Saverio Capuano III, Christina M. Newman, Jens H. Kuhn, Andres Mejia, Heather A. Simmons, and David H. O'Connor

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Discovery of driver non-coding splice-site-creating mutations in cancer, Song Cao, Daniel Cui Zhou, Clara Oh, Reyka G. Jayasinghe, Yanyan Zhao, Christopher J. Yoon, Matthew A. Wyczalkowski, Matthew H. Bailey, Terrence Tsou, Qingsong Gao, Andrew Malone, Sheila Reynolds, Ilya Shmulevich, Michael C. Wendl, Feng Chen, and Li Ding

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Disrupting flight increases sleep and identifies a novel sleep-promoting pathway in Drosophila, K Melnattur, B Zhang, and P J Shaw

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Dissemination and implementation research in sports and exercise medicine and sports physical therapy: Translating evidence to practice and policy, Oluwatoyosi B A Owoeye, Rachel S Rauvola, and Ross C Brownson

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Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm, Philip A Mudd, Jackson S Turner, Daniel Reynolds, Diane Bender, Adrianus C M Boon, Stacey L House, Kenneth E Remy, Richard S Hotchkiss, Rachel M Presti, Jane A O'Halloran, William G Powderly, Ali H Ellebedy, and et al

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Distinct neural networks associated with obsession and delusion: A connectome-wide association study, Tae Young Lee, Wi Hoon Jung, Yoo Bin Kwak, Youngwoo B Yoon, Junhee Lee, Minah Kim, Euitae Kim, and Jun Soo Kwon

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dmPFC-vlPAG projection neurons contribute to pain threshold maintenance and antianxiety behaviors, Jun-Bin Yin, Yang Bai, Yi Sun, Zhen-Yu Wu, Hui Li, Zhou-Feng Chen, and et al

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DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner, Patrick L. Collins, Caitlin Purman, Sofia I. Porter, Vincent Nganga, Ankita Saini, Katharina E. Hayer, Greer L. Gurewitz, Barry P. Sleckman, Jeffrey J. Bednarski, Craig H. Bassing, and Eugene M. Oltz