Submissions from 2021
Enhanced efficacy and increased long-term toxicity of CNS-directed, AAV-based combination therapy for Krabbe disease, Yedda Li, Christopher A Miller, Lauren K Shea, Xuntian Jiang, Miguel A Guzman, Randy J Chandler, Sai M Ramakrishnan, Stephanie N Smith, Charles P Venditti, Carole A Vogler, Daniel S Ory, Timothy J Ley, and Mark S Sands
Gut Helicobacter presentation by multiple dendritic cell subsets enables context-specific regulatory T cell generation, Emilie V. Russler-Germain, Jaeu Yi, Shannon Young, Katherine Nutsch, Harikesh S. Wong, Teresa L. Ai, Jiani N. Chai, Vivek Durai, Daniel H. Kaplan, Ronald N. Germain, Kenneth M. Murphy, and Chyi-Song Hsieh
Seroprevalence of SARS-CoV-2 antibodies in children and adults in St. Louis, Missouri, USA, Brittany K Smith, Andrew B Janowski, Jonathan E Danis, Ian B Harvey, Haiyan Zhao, Ya-Nan Dai, Christopher W Farnsworth, Ann M Gronowski, Stephen Roper, Daved H Fremont, and David Wang
SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance, Maurizio Fazio, Charles K. Kaufman, and et al
ANA Webinars: Implementation of a conference-based virtual networking event, Bhooma Aravamuthan, Eric C Landsness, and Elizabeth Silbermann
A timely call to arms: COVID-19, the circadian clock, and critical care, Jeffrey Haspel, Minjee Kim, Phyllis Zee, Tanja Schwarzmeier, Sara Montagnese, Satchidananda Panda, Adriana Albani, and Martha Merrow
Capsule carbohydrate structure determines virulence in Acinetobacter baumannii, Yuli Talyansky, Travis B. Nielsen, Jun Yan, Ulrike Carlino-Macdonald, Gisela Di Venanzio, Somnath Chakravorty, Amber Ulhaq, Mario F. Feldman, Thomas A. Russo, Evgeny Vinogradov, Brian Luna, Meredith S. Wright, Mark D. Adams, and Brad Spellberg
CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14, Bruce K Patterson, Philip A Mudd, and et al
Characterization and localization of antigens for serodiagnosis of human paragonimiasis, Kurt C Curtis, Kerstin Fischer, Young-Jun Choi, Makedonka Mitreva, Gary J Weil, and Peter U Fischer
Clinical validation of combinatorial pharmacogenomic testing and single-gene guidelines in predicting psychotropic medication blood levels and clinical outcomes in patients with depression, Anthony J Rothschild, Charles R Conway, and et al.
Decoding visual information from high-density diffuse optical tomography neuroimaging data, Kalyan Tripathy, Zachary E Markow, Andrew K Fishell, Arefeh Sherafati, Tracy M Burns-Yocum, Mariel L Schroeder, Alexandra M Svoboda, Adam T Eggebrecht, Mark A Anastasio, Bradley L Schlaggar, and Joseph P Culver
Evaluating cognitive relationships with resting-state and task-driven blood oxygen level-dependent variability, Peter R Millar, Beau M Ances, Brian A Gordon, Tammie L S Benzinger, John C Morris, and David A Balota
Evaluation of tumor immunity after administration of conditionally replicative adenoviral vector in canine osteosarcoma patients, Payal Agarwal, Elizabeth A Gammon, Maninder Sandey, Stephanie S Lindley, Jey W Koehler, Brad M Matz, Annette N Smith, Elena A Kashentseva, Igor P Dmitriev, David T Curiel, and Bruce F Smith
Flortaucipir (tau) PET in LGI1 antibody encephalitis, Gregory S Day, Brian A Gordon, Austin McCullough, Robert C Bucelli, Richard J Perrin, Tammie L S Benzinger, and Beau M Ances
Fronto-cerebellar connectivity mediating cognitive processing speed, Clive H Y Wong, Jiao Liu, Tatia M C Lee, Jing Tao, Alex W K Wong, Bolton K H Chau, Lidian Chen, and Chetwyn C H Chan
Global, cell non-autonomous gene regulation drives individual lifespan among isogenic C. elegans, Holly E. Kinser, Matthew C. Mosley, Isaac B. Plutzer, and Zachary Pincus
Liver transplantation: Expanding the donor and recipient pool, Ola Ahmed and M. B. Majella Doyle
NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis, I M Berke, E Jain, B Yavuz, T McGrath, L Chen, M J Silva, G Mbalaviele, F Guilak, D L Kaplan, and L A Setton
Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants, Elmo Christian Saarentaus, Lei Chen, Ira M Hall, and et al
Prognostic and predictive effect of KRAS gene copy number and mutation status in early stage non-small cell lung cancer patients, Andrea S. Fung, Maryam Karimi, Stefan Michiels, Lesley Seymour, Elisabeth Brambilla, Thierry Le-Chevalier, Jean-Charles Soria, Robert Kratzke, Stephen L. Graziano, Siddhartha Devarakonda, Ramaswamy Govindan, Ming-Sound Tsao, Frances A. Shepherd, and LACE-Bio Collaborative Group
Progress towards onchocerciasis elimination in Côte d'Ivoire: A geospatial modelling study, Obiora A. Eneanya, Benjamin G. Koudou, Meite Aboulaye, Aba Ange Elvis, Yeo Souleymane, Marie-Madeleine Kouakou, Gary J. Weil, and Peter U. Fischer
Quantitative proteomic analysis of diabetes mellitus in heart failure with preserved ejection fraction, Thomas C Hanff, Ali Javaheri, and et al
Robotic bronchoscopy for peripheral pulmonary lesions: A multicenter pilot and feasibility study (BENEFIT), Alexander C Chen, Nicholas J Pastis Jr, Amit K Mahajan, Sandeep J Khandhar, Michael J Simoff, Michael S Machuzak, Joseph Cicenia, Thomas R Gildea, and Gerard A Silvestri
Suspected metal allergy and femoral loosening after total knee arthroplasty: A diagnostic dilemma, Elizabeth G Lieberman, Robert L Barrack, and Thomas P Schmalzried
The effect of the COVID-19 pandemic on hip and knee arthroplasty patients in the United States: A multicenter update to the previous survey, Timothy S Brown, Christopher A Anthony, and et al
The role of endometrial sampling for surveillance of recurrence in postmenopausal patients with medically inoperable stage I endometrial cancer, Angelina Carey-Love, Mary M Mullen, Abigail Zamorano, Stephanie Markovina, Andrea R Hagemann, Katherine C Fuh, Premal H Thaker, David G Mutch, Matthew A Powell, and Lindsay M Kuroki
"It's way more than just writing a prescription": A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use disorder, Elizabeth C Saunders, Sarah K Moore, Olivia Walsh, Stephen A Metcalf, Alan J Budney, Patricia Cavazos-Rehg, Emily Scherer, and Lisa A Marsch
Mapping the immune environment in clear cell renal carcinoma by single-cell genomics, Nicholas Borcherding, Ajaykumar Vishwakarma, Andrew P Voigt, Andrew Bellizzi, Jacob Kaplan, Kenneth Nepple, Aliasger K Salem, Russell W Jenkins, Yousef Zakharia, and Weizhou Zhang
Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma, Richa Rathore, Katharine E Caldwell, Charles Schutt, Caitlyn B Brashears, Bethany C Prudner, William R Ehrhardt, Cheuk Hong Leung, Heather Lin, Najat C Daw, Hannah C Beird, Abigail Giles, Wei-Lien Wang, Alexander J Lazar, John S A Chrisinger, J Andrew Livingston, and Brian A Van Tine
Polyclonal epitope mapping reveals temporal dynamics and diversity of human antibody responses to H5N1 vaccination, Julianna Han, Aaron J Schmitz, Sara T Richey, Ya-Nan Dai, Hannah L Turner, Bassem M Mohammed, Daved H Fremont, Ali H Ellebedy, and Andrew B Ward
Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder, Xiaoming Jia, Fernando S Goes, Adam E Locke, Duncan Palmer, Weiqing Wang, and et al
Genomic characterization of emerging bacterial uropathogen Neisseria meningitidis, which was misidentified as Neisseria gonorrhoeae by nucleic acid amplification testing, Kimberley V Sukhum, Sophonie Jean, Meghan Wallace, Neil Anderson, C A Burnham, and Gautam Dantas
Nanoparticle T-cell engagers as a modular platform for cancer immunotherapy, Kinan Alhallak, Jennifer Sun, Katherine Wasden, Nicole Guenthner, Julie O'Neal, Barbara Muz, Justin King, Daniel Kohnen, Ravi Vij, Samuel Achilefu, John F DiPersio, and Abdel Kareem Azab
Central venous catheter adverse events are not associated with crowding indicators, Daniel L Theodoro, Niraj Vyas, Enyo Ablordeppey, Brian Bausano, Stephanie Charshafian, Phillip Asaro, and Richard T Griffey
Implications of oligomeric amyloid-beta (oAβ42) signaling through α7β2-nicotinic acetylcholine receptors (nAChRs) on basal forebrain cholinergic neuronal intrinsic excitability and cognitive decline, Andrew A George, Jaime M Vieira, Cameron Xavier-Jackson, Michael T Gee, John R Cirrito, Heather A Bimonte-Nelson, Marina R Picciotto, Ronald J Lukas, and Paul Whiteaker
Naturalistic language input is associated with resting-state functional connectivity in infancy, Lucy S. King, M. Catalina Camacho, David F. Montez, Kathryn L. Humphreys, and Ian H. Gotlib
Short-term effects of appropriate empirical antimicrobial treatment with ceftolozane/tazobactam in a swine model of nosocomial pneumonia, Ana Motos, Marin Kollef, and et al
Coxsackievirus B3 infection early in pregnancy induces congenital heart defects through suppression of fetal cardiomyocyte proliferation, Vipul Sharma, Lisa S Goessling, Anoop K Brar, Chetanchandra S Joshi, Indira U Mysorekar, and Pirooz Eghtesady
Death and myocardial infarction following initial revascularization versus optimal medical therapy in chronic coronary syndromes with myocardial ischemia: A systematic review and meta-analysis of contemporary randomized controlled trials, Andrea Soares, William E Boden, Whady Hueb, Maria M Brooks, Helen E A Vlachos, Kevin O'Fee, Angela Hardi, and David L Brown
SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike, Jenna J Guthmiller, Ya-Nan Dai, Christopher A Nelson, Paige D Hall, Daved H Fremont, and et al
Designing and undertaking randomised implementation trials: Guide for researchers, Luke Wolfenden, Robbie Foy, Justin Presseau, Jeremy Grimshaw, Noah Ivers, Byron Powell, Monica Taljaard, John Wiggers, Rachel Sutherland, Nicole Nathan, Christopher Williams, Melanie Kingsland, Andrew Milat, Rebecca Hodder, and Sze Lin Yoong
Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism, J L Fachi, L P Pral, J A C Dos Santos, A C Codo, S de Oliveira, J S Felipe, F F F Zambom, N O S Câmara, P M M M Vieira, M Colonna, and M A R Vinolo
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition, Allison J. Greaney, Paul W. Rothlauf, Zhuoming Liu, Sean P. J. Whelan, and et al.
Randomized controlled trial of oral vancomycin treatment in Clostridioides difficile-colonized patients, Skye R S Fishbein, Tiffany Hink, Kimberly A Reske, Candice Cass, Emily Struttmann, Zainab Hassan Iqbal, Sondra Seiler, Jennie H Kwon, C A Burnham, Gautam Dantas, and Erik R Dubberke
Developmental stage-specific changes in protein synthesis differentially sensitize hematopoietic stem cells and erythroid progenitors to impaired ribosome biogenesis, Jeffrey A Magee and Robert A J Signer
Dynamic shifts in the composition of resident and recruited macrophages influence tissue remodeling in NASH, Sabine Daemen, Anastasiia Gainullina, Gowri Kalugotla, Li He, Mandy M Chan, Joseph W Beals, Kim H Liss, Samuel Klein, Ariel E Feldstein, Brian N Finck, Maxim N Artyomov, and Joel D Schilling
Zika virus oncolytic activity requires CD8+ T cells and is boosted by immune checkpoint blockade, Sharmila Nair, Luciano Mazzoccoli, Arijita Jash, Jennifer Govero, Sachendra S Bais, Tong Hu, Camila R Fontes-Garfias, Chao Shan, Hideho Okada, Sujan Shresta, Jeremy N Rich, Pei-Yong Shi, Michael S Diamond, and Milan G Chheda
The Dark Kinase Knowledgebase: An online compendium of knowledge and experimental results of understudied kinases, Matthew E. Berginski, Nienke Moret, Changchang Liu, Dennis Goldfarb, Peter K. Sorger, and Shawn M. Gomez
Relationship between clinicopathologic factors and FDG avidity in radioiodine-negative recurrent or metastatic differentiated thyroid carcinoma, Le Ngoc Ha, Amir Iravani, Nguyen Thi Nhung, Ngo Thi Minh Hanh, Febby Hutomo, and Mai Hong Son
Application of systems dynamics and group model building to identify barriers and facilitators to acute care delivery in a resource limited setting, Fiona Muttalib, Ellis Ballard, Josephine Langton, Sara Malone, Yudy Fonseca, Andreas Hansmann, Kenneth Remy, Peter Hovmand, and Allan Doctor
Small molecule SARM1 inhibitors recapitulate the SARM1 -/- phenotype and allow recovery of a metastable pool of axons fated to degenerate, Robert O Hughes, Todd Bosanac, Xianrong Mao, Thomas M Engber, Aaron DiAntonio, Jeffrey Milbrandt, Rajesh Devraj, and Raul Krauss
Function of mammalian M-cones depends on the level of CRALBP in Müller cells, Alexander V. Kolesnikov, Philip D. Kiser, Krzysztof Palczewski, and Vladimir J. Kefalov
4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor, Ofer Moldavski, Peter-James H. Zushin, Charles A. Berdan, Robert J. Van Eijkeren, Xuntian Jiang, Mingxing Qian, Daniel S. Ory, Douglas F. Covey, Daniel K. Nomura, Andreas Stahl, Ethan J. Weiss, and Roberto Zoncu
AAPM medical physics practice guideline 3.b.: Levels of supervision for medical physicists in clinical training, Douglas Pfeiffer, Hania Al-Hallaq, Per Halvorsen, Kristi Hendrickson, Zheng Feng Lu, Melissa Carol Martin, Beth Schueler, Jillian Shuman, and Jacqueline E Zoberi
Ablative five-fraction stereotactic body radiation therapy for inoperable pancreatic cancer using online MR-guided adaptation, Comron Hassanzadeh, Soumon Rudra, Ani Bommireddy, William G Hawkins, Andrea Wang-Gillam, Ryan C Fields, Bin Cai, Justin Park, Olga Green, Michael Roach, Lauren Henke, and Hyun Kim
A bone-specific adipogenesis pathway in fat-free mice defines key origins and adaptations of bone marrow adipocytes with age and disease, Xiao Zhang, Hero Robles, Kristann L. Magee, Madelyn R. Lorenz, Zhaohua Wang, Charles A. Harris, Clarissa S. Craft, and Erica L. Scheller
Academic performance of children with sickle cell disease in the United States: A meta-analysis, Andrew M Heitzer, Latacha Hamilton, Claire Stafford, Jeffrey Gossett, Lara Ouellette, Ana Trpchevska, Allison A King, Guolian Kang, and Jane S Hankins
A canker barking at the wrong knee: Thyronectria austroamericana septic arthritis, Sasinuch Rutjanawech, Carlos Mejia-Chew, Chapelle Ayres, and Andrej Spec
Acanthamoeba keratitis, pathology, diagnosis and treatment, Nicholas Fanselow, Nadia Sirajuddin, Xiao-Tang Yin, Andrew J W Huang, and Patrick M Stuart
Acaricidal activity of Foeniculum vulgare against Rhipicephalus annulatus is mainly dependent on its constituent from trans-anethone, Shawky M. Aboelhadid, Waleed M. Arafa, Abdel-Azeem S. Abdel-Baki, Atalay Sokmen, Saleh Al-Quraishy, Ahmed O. Hassan, and Asmaa A. Kamel
A Casz1–NuRD complex regulates temporal identity transitions in neural progenitors, Pierre Mattar, Christine Jolicoeur, Thanh Dang, Sujay Shah, Brian S. Clark, and Michel Cayouette
Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease, Julie Gonneaud, Brian A. Gordon, Carlos Cruchaga, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Susan Brandon, Virginia Buckles, Tamara Donahue, Anne Fagan, Gigi Flynn, Erin Franklin, Cortaiga Gant, Julia Gray, Alexander Groves, Jason Hassenstab, Laura Hoechst-Swisher, David Holtzman, Russ Hornbeck, Gina Jerome, Celeste Karch, Denise Maue-Dreyfus, Eric McDade, Joanne Norton, Richard Perrin, Marc Raichle, Wendy Sigurdson, Peter Wang, Chengjie Xiong, Xiong Xu, Nigel J. Cairns, Erin Householder, Lisa Taylor Reinwald, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, and et al
Acceleration of small intestine development and remodeling of the microbiome following hyaluronan 35 KDa treatment in neonatal mice, Hala Chaaban, Kathryn Burge, Jeffrey Eckert, MaJoi Trammell, David Dyer, Ravi S Keshari, Robert Silasi, Girija Regmi, Cristina Lupu, Misty Good, Steven J McElroy, and Florea Lupu
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice, Benjamin Caballero, Celeste M. Karch, and et al.
Achieving a diverse, equitable, and inclusive environment for the Black orthopaedic surgeon: Part 1: Barriers to successful recruitment of Black applicants, Gabriella E Ode, Letitia Bradford, William A Ross, Eric W Carson, and Jaysson T Brooks
A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution, Wesley C. Warren, Chad Tomlinson, Milinn Kremitzki, Tina Graves-Lindsay, and et al.
Acitretin mitigates uroporphyrin‑induced bone defects in congenital erythropoietic porphyria models, Juliana Bragazzi Cunha, Jared S. Elenbaas, Dhiman Maitra, Ning Kuo, Rodrigo Azuero-Dajud, Allison C. Ferguson, Megan S. Griffin, Stephen I. Lentz, Jordan A. Shavit, and M. Bishr Omary
A clinician's guide for navigating the world of attention deficit hyperactivity disorder medications, Gregory W Mattingly and Joel Young
A comparison of prediction approaches for identifying prodromal Parkinson disease, Mark N. Warden, Susan Searles Nielsen, Alejandra Camacho-Soto, Roman Garnett, and Brad A. Racette
A comprehensive review of tic disorders in children, Keisuke Ueda and Kevin J Black
A cross-sectional comparison of physical activity during COVID-19 in a sample of rural and non-rural participants in the US, Alan M Beck, Amanda S Gilbert, Dixie D Duncan, and Eric M Wiedenman
Activated microglia mitigate Aβ-associated tau seeding and spreading, Maud Gratuze, Yun Chen, Samira Parhizkar, Nimansha Jain, Michael R. Strickland, Javier Remolina Serrano, Marco Colonna, Jason D. Ulrich, and David M. Holtzman
Acupuncture and oxytocinergic system: The promising treatment for autism, Tangfeng Su and Lei Pei
Acute acalculous cholecystitis-associated bacteremia has worse outcome, Javier E. Rincon, Rohit K. Rasane, Jose A. Aldana, Christina X. Zhang, Ricardo A. Fonseca, Qiao Zhang, Kelly M. Bochicchio, Obeid N. Ilahi, and Grant V. Bochicchio
Acute symptoms of mild to moderate COVID-19 are highly heterogeneous across individuals and over time, Thomas L. Rodebaugh, Madelyn R. Frumkin, Angela M. Reiersen, Eric J. Lenze, Michael S. Avidan, J. Philip Miller, Jay F. Piccirillo, Charles F. Zorumski, and Caline Mattar
A decade in review after Idiopathic Scoliosis was first called a complex trait-A tribute to the late Dr. Yves Cotrel for his support in studies of etiology of scoliosis, Nelson L S Tang, Matthew B Dobbs, Christina A Gurnett, Yong Qiu, T P Lam, Jack C Y Cheng, and Nancy Hadley-Miller
Adherence of internet-based cancer risk assessment tools to best practices in risk communication: Content analysis, Erika A Waters, Jeremy L Foust, Laura D Scherer, Amy McQueen, and Jennifer M Taber
Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox, Biswajit Khatua, Bara El-Kurdi, Krutika Patel, Christopher Rood, Pawan Noel, Michael Crowell, Jordan R Yaron, Sergiy Kostenko, Andre Guerra, Douglas O Faigel, Mark Lowe, and Vijay P Singh
Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis, Yi Zhu, Gordon I. Smith, Samuel Klein, and et al
Adolescent animal product intake in relation to later prostate cancer risk and mortality in the NIH-AARP Diet and Health Study, Tuo Lan, Yikyung Park, Graham A Colditz, Jingxia Liu, Rashmi Sinha, Molin Wang, Kana Wu, Edward Giovannucci, and Siobhan Sutcliffe
Adolescent idiopathic scoliosis treated by posterior spinal segmental instrumented fusion : When is fusion to L3 stable?, Seung-Jae Hyun, Lawrence G. Lenke, Yongjung Kim, Keith H. Bridwell, Meghan Cerpa, and Kathy M. Blanke
A domestic cat whole exome sequencing resource for trait discovery, Alana R. Rodney, Rueben M. Buckley, Robert S. Fulton, Catrina Fronick, Todd Richmond, Christopher R. Helps, Peter Pantke, Dianne J. Trent, Karen M. Vernau, John S. Munday, Andrew C. Lewin, Rondo Middleton, Leslie A. Lyons, and Wesley C. Warren
Adult patient preferences for long-acting ADHD treatments: A discrete choice experiment, M Janelle Cambron-Mellott, Jaromir Mikl, Joana E Matos, Jennifer G Erensen, Kathleen Beusterien, Marc J Cataldo, Bernadette Hallissey, and Gregory W Mattingly
Advances in genetic and molecular understanding of Alzheimer's disease, Laura Ibanez, Carlos Cruchaga, and Maria Victoria Fernández
Advantages of 18F-FDG PET/CT imaging over modified Duke criteria and clinical presumption in patients with challenging suspicion of infective endocarditis, Valentin Pretet, Cyrille Blondet, Yvon Ruch, Matias Martinez, Soraya El Ghannudi, Olivier Morel, Yves Hansmann, Thomas H Schindler, and Alessio Imperiale
African Americans have differences in CSF soluble TREM2 and associated genetic variants, Suzanne E. Schindler, Carlos Cruchaga, Amulya Jospeh, Lena McCue, Fabiana H.G. Farias, Consuelo H. Wilkins, Yuetiva Deming, Rachel L. Henson, Robert J. Mikesell, Laura Piccio, Jorge J. Llibre-Guerra, Krista L. Moulder, Anne M. Fagan, Beau M. Ances, Tammie L.S. Benzinger, Chengjie Xiong, David M. Holtzman, and John C. Morris
A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor, Akira Inoue, Laura J Janke, Brian L Gudenas, Hongjian Jin, Yiping Fan, Joshua Paré, Michael R Clay, Paul A Northcott, Angela C Hirbe, and Xinwei Cao
A genome-engineered bioartificial implant for autoregulated anticytokine drug delivery, Yun-Rak Choi, Kelsey H Collins, Luke E Springer, Lara Pferdehirt, Alison K Ross, Chia-Lung Wu, Franklin T Moutos, Natalia S Harasymowicz, Jonathan M Brunger, Christine T N Pham, and Farshid Guilak
Aging-associated deficit in CCR7 is linked to worsened glymphatic function, cognition, neuroinflammation, and β-amyloid pathology, Sandro Da Mesquita, Jasmin Herz, Morgan Wall, Taitea Dykstra, Kalil Alves de Lima, Geoffrey T Norris, Nisha Dabhi, Tatiana Kennedy, Wendy Baker, and Jonathan Kipnis
A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis, Lisa K. McLellan, Michael R. McAllaster, Arthur S. Kim, Ľubomíra Tóthová, Patrick D. Olson, Jerome S. Pinkner, Allyssa L. Daugherty, Teri N. Hreha, James W. Janetka, Daved H. Fremont, Scott J. Hultgren, Herbert W. Virgin, and David A. Hunstad
Air pollution particulate matter amplifies white matter vascular pathology and demyelination caused by hypoperfusion, Mikko T Huuskonen, Qinghai Liu, Krista Lamorie-Foote, Kristina Shkirkova, Michelle Connor, Arati Patel, Axel Montagne, Hans Baertsch, Constantinos Sioutas, Todd E Morgan, Caleb E Finch, Berislav V Zlokovic, and William J Mack
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis, David Pradella, William Vermi, and et al
All epidural needle bevels are not the same, Amber C. Benhardt and Bhavani Shankar Kodali
Allosteric effects of SSB C-terminal tail on assembly of E. coli RecOR proteins, Min Kyung Shinn, Alexander G. Kozlov, and Timothy M. Lohman
Altered mapping of sound frequency to cochlear place in ears with endolymphatic hydrops provide insight into the pitch anomaly of diplacusis, J.J. Guinan Jr., S.M. Lefler, C.A. Buchman, S.S. Goodman, and J.T. Lichtenhan
A machine learning approach for the factorization of psychometric data with application to the Delis Kaplan Executive Function System, J.A. Camilleri, S.B. Eickhoff, S. Weis, J. Chen, J. Amunts, A. Sotiras, and S. Genon
American Society of Hematology 2021 guidelines for sickle cell disease: Stem cell transplantation, Julie Kanter, Robert I. Liem, Françoise Bernaudin, Javier Bolaños-Meade, Courtney D. Fitzhugh, Jane S. Hankins, M. Hassan Murad, Julie A. Panepinto, Damiano Rondelli, Shalini Shenoy, John Wagner, Mark C. Walters, Teonna Woolford, Joerg J. Meerpohl, and John Tisdale
American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19, Adam Cuker, Kristen M. Sanfilippo, and et al.
A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure, Raymond J. Langley, Patrick Luckett, and et al.
A microfluidic-based filtration system to enrich for bone marrow disseminated tumor cells from breast cancer patients, Sreeraj G. Pillai, Chidananda M. Siddappa, Cynthia Ma, Jackie Snider, Madhurima Kaushal, Mark A. Watson, and Rebecca Aft