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Submissions from 2022

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Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins, Cliff J Luke, Stephanie Markovina, Misty Good, Ira E Wight, Brian J Thomas, John M Linneman, Wyatt E Lanik, Olga Koroleva, Maggie R Coffman, Mark T Miedel, Qingqing Gong, Arlise Andress, Marlene Campos Guerrero, Songyan Wang, LiYun Chen, Wandy L Beatty, Kelsey N Hausmann, Frances V White, James A J Fitzpatrick, Anthony Orvedahl, Stephen C Pak, and Gary A Silverman

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Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum, Alex Reichenbach, Alexxai V. Kravitz, and et al

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Myocardial afterload is a key biomechanical regulator of atrioventricular myocyte differentiation in zebrafish, Neha Ahuja, Paige Ostwald, Alex Gendernalik, Elena Guzzolino, Letizia Pitto, David Bark, and Deborah M Garrity

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SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation, Songyan Wang, Cliff J Luke, Stephen C Pak, Victoria Shi, Liyun Chen, Jonathan Moore, Arlise P Andress, Kay Jayachandran, Jin Zhang, Yi Huang, Marina Platik, Anthony A Apicelli, Julie K Schwarz, Perry W Grigsby, Gary A Silverman, and Stephanie Markovina

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The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants, Chang Liu, Rita E Chen, Michael S Diamond, and et al.

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Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction, Lubov A. Ezerskiy, Kathleen M. Schoch, Chihiro Sato, Mariana Beltcheva, Kanta Horie, Frank Rigo, Ryan Martynowicz, Celeste M. Karch, Randall J. Bateman, and Timothy M. Miller

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FASN-dependent de novo lipogenesis is required for brain development, Daniel Gonzalez-Bohorquez, Isabel M Gallego López, Baptiste N Jaeger, Sibylle Pfammatter, Megan Bowers, Clay F Semenkovich, and Sebastian Jessberger

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p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes, Vitor F. Martins, Gretchen A. Meyer, and et al.

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Targeting the fusion process of SARS-CoV-2 infection by small molecule inhibitors, Seung Bum Park, Parker Irvin, Zongyi Hu, Mohsin Khan, Xin Hu, Qiru Zeng, Catherine Chen, Miao Xu, Madeleine Leek, Ruochen Zang, James Brett Case, Wei Zheng, Siyuan Ding, and T. Jake Liang

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Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract, Jianan Zhang, Morgan E. Walker, Katherine Z. Sanidad, Hongna Zhang, Michael B. Major, Dennis Goldfarb, and et al

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Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition, Rebecca Rimbach, Susan B. Racette, John R. Speakman, Herman Pontzer, and et al

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Droplet precautions on-site (DroPS) during the influenza season 2018/2019: A possible alternative to single room isolation for respiratory viral infections, Michèle Birrer, Martin Perrig, Fabienne Hobi, Christina Gfeller, Andrew Atkinson, Martin Egger, Corinne Bartholdi, Drahomir Aujesky, Jonas Marschall, and Rami Sommerstein

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Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival, Deep Hathi, Chantiya Chanswangphuwana, Nicholas Cho, Francesca Fontana, Dolonchampa Maji, Julie Ritchey, Julie O'Neal, Anchal Ghai, Kathleen Duncan, Walter J Akers, Mark Fiala, Ravi Vij, John F DiPersio, Michael Rettig, and Monica Shokeen

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An informed approach to the development of primary care pediatric firearm safety messages, Lindsay N Fuzzell, Sherry Dodd, Sisi Hu, Amanda Hinnant, Sungkyoung Lee, Glen Cameron, and Jane M Garbutt

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Does data-independent acquisition data contain hidden gems? A case study related to Alzheimer's disease, Evan E Hubbard, Randall J Bateman, Richard J Perrin, and et al.

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Effect of aerobic or resistance exercise, or both, on intermuscular and visceral fat and physical and metabolic function in older adults with obesity while dieting, Debra L Waters, Lina Aguirre, Burke Gurney, David R Sinacore, Kenneth Fowler, Giulia Gregori, Reina Armamento-Villareal, Clifford Qualls, and Dennis T Villareal

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OncoDB: An interactive online database for analysis of gene expression and viral infection in cancer, Gongyu Tang, Minsu Cho, and Xiaowei Wang

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Transcriptomes of peripheral blood mononuclear cells from juvenile dermatomyositis patients show elevated inflammation even when clinically inactive, Elisha D O Roberson, Rosana A Mesa, Gabrielle A Morgan, Li Cao, Wilfredo Marin, and Lauren M Pachman

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Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients, A Joseph Bloom, Xianrong Mao, Amy Strickland, Yo Sasaki, Jeffrey Milbrandt, and Aaron DiAntonio

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Percepta Genomic Sequencing Classifier and decision-making in patients with high-risk lung nodules: A decision impact study, Sonali Sethi, Scott Oh, Alexander Chen, Christina Bellinger, Lori Lofaro, Marla Johnson, Jing Huang, Sangeeta Maruti Bhorade, William Bulman, and Giulia C Kennedy

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Place is power: Investing in communities as a systemic leverage point to reduce breast cancer disparities by race, Matthew Jay Lyons, Senaida Fernandez Poole, Ross C Brownson, and Rodney Lyn

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Coordination of sustainable financing for evidence-based youth mental health treatments: Protocol for development and evaluation of the fiscal mapping process, Alex R Dopp, Marylou Gilbert, Jane Silovsky, Jeanne S Ringel, Susan Schmidt, Beverly Funderburk, Ashley Jorgensen, Byron J Powell, Douglas A Luke, David Mandell, Daniel Edwards, Mellicent Blythe, and Dana Hagele

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Polyunsaturated fatty acids inhibit a pentameric ligand-gated ion channel through one of two binding sites, Noah M. Dietzen, Mark J. Arcario, Lawrence J. Chen, John T. Petroff, K. Trent Moreland, Kathiresan Krishnan, Grace Brannigan, Douglas F. Covey, and Wayland W.I. Cheng

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Procedural Risk in Congenital Cardiac Catheterization (PREDIC3T), Brian P Quinn, David Balzer, and et al

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SARS-CoV-2 spreads through cell-to-cell transmission, Cong Zeng, John P Evans, Tiffany King, Yi-Min Zheng, Eugene M Oltz, Sean P J Whelan, Linda J Saif, Mark E Peeples, and Shan-Lu Liu

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The Yersinia high-pathogenicity island encodes a siderophore-dependent copper response system in uropathogenic Escherichia coli, George L Katumba, Hung Tran, and Jeffrey P Henderson

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Transcriptional profile and chromatin accessibility in zebrafish melanocytes and melanoma tumors, Eva Kramer, Paula Godoy, and Charles Kaufman

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Comparison of ETDRS 7-field to 4-widefield digital imaging in the evaluation of diabetic retinopathy severity, Barbara A Blodi, Amitha Domalpally, Ashley H Tjaden, Nancy Barrett, Emily Y Chew, William C Knowler, Christine G Lee, Xavier Pi-Sunyer, Amisha Wallia, Neil H White, and Marinella Temprosa

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3D bi-directional transformer U-Net for medical image segmentation, Xiyao Fu, Zhexian Sun, Haoteng Tang, Eric M Zou, Heng Huang, Yong Wang, and Liang Zhan

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Abnormal synergies and associated reactions post-hemiparetic stroke reflect muscle activation patterns of brainstem motor pathways, Laura M McPherson and Julius P A Dewald

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Academic medical center clinical research professional workforce: Part 2 - issues in staff onboarding and professional development, Jacqueline M Knapke, Michelle Jenkerson, Peg Tsao, Stephanie Freel, Jessica Fritter, Shirley L Helm, Penelope Jester, H Robert Kolb, Angela Mendell, Megan Petty, and Carolynn T Jones

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A callosal biomarker of behavioral intervention outcomes for autism spectrum disorder? A case-control feasibility study with diffusion tensor imaging, Javier Virues-Ortega, Nicole S. McKay, Jessica C. McCormack, Nerea Lopez, Rosalie Liu, and Ian Kirk

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A case of Gorham-Stout disease of the skull base treated with intensity modulated radiation therapy, Amit Roy, Neal Andruska, Randall Brenneman, Jacob Hogan, Hilary L P Orlowski, Patrik Pipkorn, and Mackenzie D Daly

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A comparison of 64Cu-labeled bi-terminally PEGylated A20FMDV2 peptides targeting integrin ανβ6, Truc T Huynh, Sreeja Sreekumar, Cedric Mpoy, and Buck E Rogers

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A conformational variant of p53 (U-p53AZ) as blood-based biomarker for the prediction of the onset of symptomatic Alzheimer's disease, S Piccirella, L Van Neste, C Fowler, C L Masters, J Fripp, J D Doecke, C Xiong, D Uberti, and P Kinnon

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A content analysis of 100 qualitative health research articles to examine researcher-participant relationships and implications for data sharing, Jessica Mozersky, Annie Friedrich, and James DuBois

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Actin capping protein regulates postsynaptic spine development through CPI-motif interactions, Kenneth R Myers, Yanjie Fan, Patrick McConnell, John A Cooper, and James Q Zheng

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Advances and gaps in SARS-CoV-2 infection models, César Muñoz-Fontela, Michael S. Diamond, and et al

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Advances in our clinical understanding of autonomic regulation therapy using vagal nerve stimulation in patients living with heart failure, Marvin A Konstam, Douglas L Mann, John James E Udelson, Jeffrey L Ardell, Gaetano M De Ferrari, Martin R Cowie, Helmut U Klein, Douglas D Gregory, Joseph M Massaro, Imad Libbus, Lorenzo A DiCarlo, Javed Butler, John D Parker, and John R Teerlink

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Advances in understanding interferon-mediated immune responses to enteric viruses in intestinal organoids, Lila S Nolan and Megan T Baldridge

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Adverse events related to ultrasound-guided regional anesthesia performed by Emergency Physicians: Systematic review protocol, Sean P. Stickles, Deborah Shipley Kane, Chadd K. Kraus, Robert J. Strony, Enyo A. Ablordeppey, Michelle M. Doering, Daniel Theodoro, Jacques Simon Lee, and Christopher R. Carpenter

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A framework for extension studies using real-world data to examine long-term safety and effectiveness, Mehmet Burcu, Cyntia B Manzano-Salgado, Anne M Butler, and Jennifer B Christian

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Age differences in the association between sleep and Alzheimer's disease biomarkers in the EPAD cohort, Sharon L Naismith, Yue Leng, Jake R Palmer, and Brendan P Lucey

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All-cause and in-hospital mortality after aspirin use in patients hospitalized with COVID-19: A systematic review and meta-analysis, Nischit Baral, Joshua D Mitchell, Pramod K Savarapu, Maxwell Akanbi, Bandana Acharya, Soumya Kambalapalli, Amith Seri, Krishna P Bashyal, Arvind Kunadi, Niranjan Ojha, Annabelle Santos Volgman, Tripti Gupta, and Timir K Paul

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Alopecia areata after mogamulizumab treatment, Neel S Raval, Nora A Alexander, Karlee De Monnin, Christine C Yokoyama, Neha Mehta-Shah, Ilana S Rosman, and Amy C Musiek

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Altered Peroxisome Proliferator-Activated Receptor alpha signaling in variably diseased peripheral arterial segments, Connor Engel, Rodrigo Meade, Nikolai Harroun, Amanda Penrose, Mehreen Shafqat, Xiaohua Jin, Gayan DeSilva, Clay Semenkovich, and Mohamed Zayed

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A map of neurofilament light chain species in brain and cerebrospinal fluid and alterations in Alzheimer's disease, Melissa M Budelier, Yingxin He, Nicolas R Barthelemy, Hong Jiang, Yan Li, Ethan Park, Rachel L Henson, Suzanne E Schindler, David M Holtzman, and Randall J Bateman

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AMIGO1 promotes axon growth and territory matching in the retina, Florentina Soto, Ning Shen, and Daniel Kerschensteiner

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Analysis and classification of postcatheterization femoral arteriovenous fistulas based on color Doppler examinations, William D Middleton and Kathryn A Robinson

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Analysis of neuronal injury transcriptional response identifies CTCF and YY1 as co-operating factors regulating axon regeneration, Oshri Avraham, Jimmy Le, Kathleen Leahy, Tiandao Li, Guoyan Zhao, and Valeria Cavalli

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Analysis of variation in pre-procedural fasting duration for common inpatient gastrointestinal procedures, Vorada Sakulsaengprapha, Michael Daniel, Jiarui Cai, Diego A. Martinez, and Simon C. Mathews

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An evidence-based definition of anemia for singleton, uncomplicated pregnancies, Amanda C. Zofkie, W. Holt Garner, Rachel C. Schell, Alexandra S. Ragsdale, Donald D. McIntire, Scott W. Roberts, and Catherine Y. Spong

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An immuno-enrichment free, validated quantification of tau protein in human CSF by LC-MS/MS, Wade Self, Khader Awwad, John Paul Savaryn, and Michael Schulz

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A novel computer adaptive word list memory test optimized for remote assessment: Psychometric properties and associations with neurodegenerative biomarkers in older women without dementia, Nikki H Stricker, John L Stricker, Aimee J Karstens, Jennifer R Geske, Julie A Fields, Jason Hassenstab, Christopher G Schwarz, Nirubol Tosakulwong, Heather J Wiste, Clifford R Jack, Kejal Kantarci, and Michelle M Mielke

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An overview of treatment options for patients with relapsed/refractory multiple myeloma and renal impairment, Meletios A Dimopoulos, Joseph Mikhael, Evangelos Terpos, Xavier Leleu, Philippe Moreau, Joan Bladé, Jin Seok Kim, Keith Stockerl-Goldstein, and Paul G Richardson

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Antibodies in healthcare personnel following severe acute respiratory syndrome coronavirus virus 2 (SARS-CoV-2) infection, Rachel E Bosserman, Christopher W Farnsworth, Caroline A O'Neil, Candice Cass, Daniel Park, Claire Ballman, Meghan A Wallace, Emily Struttmann, Henry Stewart, Olivia Arter, Kate Peacock, Victoria J Fraser, Philip J Budge, Margaret A Olsen, Carey-Ann D Burnham, Hilary M Babcock, Jennie H Kwon, and CDC Prevention Epicenters

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A perspective on implementation outcomes and strategies to promote the uptake of COVID-19 vaccines, Meagan Pilar, A Rani Elwy, Larissa Lushniak, Grace Huang, Gabriella M McLoughlin, Cole Hooley, Nisha Nadesan-Reddy, Brittney Sandler, Mosa Moshabela, Olakunle Alonge, Elvin Geng, and Enola Proctor

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A phase 1b study of telisotuzumab vedotin in combination with nivolumab in patients with NSCLC, D Ross Camidge, Daniel Morgensztern, and et al.

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APOE mediated neuroinflammation and neurodegeneration in Alzheimer's disease, Samira Parhizkar and David M Holtzman

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A polygenic risk score based on a cardioembolic stroke multitrait analysis improves a clinical prediction model for this stroke subtype, Jara Cárcel-Márquez, Laura Ibañez, Laura Heitsch, Rajat Dhar, Carlos Cruchaga, Jin-Moo Lee, and et al

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A promising genetic target for a deadly disease: Single immunoglobulin interleukin 1 (SIGIRR) mutations in necrotizing enterocolitis, Misty Good and Camilia R Martin

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A prospective cohort study of the impact of outpatient Intensive Cardiac Rehabilitation on depression and cardiac self-efficacy, Kristin M McKenzie, Lauren K Park, Eric J Lenze, Kristin Montgomery, Serene Rashdi, Elena Deych, Natalie A Stranczek, Erin J McKenzie, Michael W Rich, Valene Garr Barry, Nidhi Talpade, Tessa Carson, Linda R Peterson, Susan B Racette, Lisa de Las Fuentes, and et al.

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A prospective, multicenter trial of a long-term bioabsorbable mesh with Sepra technology in cohort of challenging laparoscopic ventral or incisional hernia repairs (ATLAS trial), William W Hope, Jeffrey A Blatnik, and et al

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A rare case of synovial sarcoma of the prostate causing urinary retention, Syed Ehsanullah, Syeda Zarmeena Rashid, Adeel Haq, and Saiyed Abdullah A. Ehsanullah

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A recombinant murine-like rotavirus with Nano-Luciferase expression reveals tissue tropism, replication dynamics, and virus transmission, Yinxing Zhu, Liliana Sánchez-Tacuba, Gaopeng Hou, Takahiro Kawagishi, Ningguo Feng, Harry B Greenberg, and Siyuan Ding

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A role for an HTLV-1 vaccine?, Lee Ratner

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Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI, Farah Deba, Kemburli Munoz, Eloisa Peredia, Gustav Akk, and Ayman K Hamouda

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Assessing the relationship of patient reported outcome measures with functional status in dysferlinopathy: A Rasch analysis approach, Anna G Mayhew, Catherine Siener, Alan Pestronk, and et al

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Assessment of a plasma amyloid probability score to estimate amyloid positron emission tomography findings among adults with cognitive impairment, Yan Hu, Barry A. Siegel, David M. Holtzman, and et al

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Association between hospital private equity acquisition and outcomes of acute medical conditions among Medicare beneficiaries, Marcelo Cerullo, Kelly Yang, Karen E. Joynt Maddox, Ryan C. McDevitt, James M. Roberts, and Anaeze C. Offodile

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Association between recent overdose and chronic pain among individuals in treatment for opioid use disorder, Sarah M. Hartz, Robert C. Culverhouse, Carrie M. Mintz, Matthew S. Ellis, Zachary A. Kasper, Patricia Cavazos-Rehg, Richard A. Grucza, Laura J. Bierut, and Theodore J. Cicero

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Association between workplace absenteeism and alcohol use disorder from the National Survey on Drug Use and Health, 2015-2019, Ian C. Parsley, Ann Marie Dale, Sherri L. Fisher, Carrie M. Mintz, Sarah M. Hartz, Bradley A. Evanoff, and Laura J. Bierut

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Association of a perioperative multicomponent fall prevention intervention with falls and quality of life after elective inpatient surgical procedures, Bradley A. Fritz, Christopher R. King, Divya Mehta, Emily Somerville, Alex Kronzer, Arbi Ben Abdallah, Troy Wildes, Michael S. Avidan, Eric J. Lenze, and Susan Stark

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Association of body mass index in midlife with morbidity burden in older adulthood and longevity, Sadiya S. Khan, Amy E. Krefman, Lihui Zhao, Lei Liu, Anna Chorniy, Martha L. Daviglus, Cuiping Schiman, Kiang Liu, Tina Shih, Daniel Garside, Thanh-Huyen T. Vu, Donald M. Lloyd-Jones, and Norrina B. Allen

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Association of multidimensional poverty with dementia in adults aged 50 years or older in South Africa, Jean-Francois Trani, Jacqueline Moodley, May Thu Thu Maw, and Ganesh M. Babulal

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Association of pretreatment hippocampal volume with neurocognitive function in patients treated with hippocampal avoidance whole brain radiation therapy for brain metastases: Secondary analysis of NRG Oncology/RTOG 0933, Christopher D. Abraham, Stephanie L. Pugh, Joseph A. Bovi, Vinai Gondi, Minesh P. Mehta, Tammie Benzinger, Christopher J. Owen, Simon S. Lo, Vijayananda Kundapur, Paul D. Brown, Alexander Y. Sun, Steven P. Howard, Albert S DeNittis, Clifford G. Robinson, and Lisa A. Kachnic

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Associations of polymorphisms in the peroxisome proliferator-activated receptor gamma coactivator-1 alpha gene with subsequent coronary heart disease: An individual-level meta-analysis, Tessa Schillemans, Sharon Cresci, and et al

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A test of the pioneer factor hypothesis using ectopic liver gene activation, Jeffrey L. Hansen, Kaiser J. Loell, and Barak A. Cohen

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At-home blood collection and stabilization in high temperature climates using home RNA, Lauren G Brown, Amanda J Haack, Dakota S Kennedy, Karen N Adams, Jennifer E Stolarczuk, Meg G Takezawa, Erwin Berthier, Sanitta Thongpang, Fang Yun Lim, Damien Chaussabel, Mathieu Garand, and Ashleigh B Theberge

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Augmented cardiac growth hormone signaling contributes to cardiomyopathy following genetic disruption of the cardiomyocyte circadian clock, Ravi Sonkar, Ryan Berry, Mary N Latimer, Sumanth D Prabhu, Martin E Young, and Stuart J Frank

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Automated detection of vaping-related tweets on Twitter during the 2019 EVALI outbreak using machine learning classification, Yang Ren, Dezhi Wu, Avineet Singh, Erin Kasson, Ming Huang, and Patricia Cavazos-Rehg

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Automated lesion detection of breast cancer in [18F] FDG PET/CT using a novel AI-Based workflow, Jeffrey P Leal, Steven P Rowe, Vered Stearns, Roisin M Connolly, Christos Vaklavas, Minetta C Liu, Anna Maria Storniolo, Richard L Wahl, Martin G Pomper, and Lilja B Solnes

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Automated measurement of net water uptake from baseline and follow-up CTs in patients with large vessel occlusion stroke, Atul Kumar, Yasheng Chen, Aaron Corbin, Ali Hamzehloo, Amin Abedini, Zeynep Vardar, Grace Carey, Kunal Bhatia, Laura Heitsch, Jamal J Derakhshan, Jin-Moo Lee, and Rajat Dhar

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Automatic wide complex tachycardia differentiation using mathematically synthesized vectorcardiogram signals, Anthony H Kashou, Sarah LoCoco, Trevon D McGill, Christopher M Evenson, Abhishek J Deshmukh, David O Hodge, Daniel H Cooper, Sandeep S Sodhi, Phillip S Cuculich, Samuel J Asirvatham, Peter A Noseworthy, Christopher V DeSimone, and Adam M May

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Avoid or embrace? Practice effects in Alzheimer's disease prevention trials, Andrew J Aschenbrenner, Jason Hassenstab, Guoqiao Wang, Yan Li, Chengjie Xiong, Eric McDade, David B Clifford, Randall J Bateman, and et al.

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Barriers and facilitators to diabetes screening and prevention after a pregnancy complicated by gestational diabetes, Drishti D. Sinha, Roxann C. Williams, Laura N. Hollar, Hannah R. Lucas, Bethany Johnson-Javois, Heidi B. Miller, Amanda Stoermer, Graham A. Colditz, Aimee S. James, and Cynthia J. Herrick

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Beta-adrenergic antagonist tolerance in amyloid cardiomyopathy, Stuart Ramsell, Carlos Arias Bermudez, Cyril Ayuk Mbeng Takem Baiyee, Brandon Rodgers, Samir Parikh, Salem Almaani, Nidhi Sharma, Samantha LoRusso, Miriam Freimer, Elyse Redder, Naresh Bumma, Ajay Vallkati, Yvonne Efebera, Rami Kahwash, and Courtney M Campbell

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Binary acoustic metasurfaces for dynamic focusing of transcranial ultrasound, Zhongtao Hu, Yaoheng Yang, Lu Xu, Yao Hao, and Hong Chen

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Bridging the technological divide: Stigmas and challenges with technology in digital brain health studies of older adults, Jessica Nicosia, Andrew J Aschenbrenner, Sarah L Adams, Marisol Tahan, Sarah H Stout, Hannah Wilks, Joyce E Balls-Berry, John C Morris, and Jason Hassenstab

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Bruton's tyrosine kinase supports gut mucosal immunity and commensal microbiome recognition in autoimmune arthritis, Rachel H Bonami, Christina E Thurman, Sonam Verma, Camille S Westlake, Lindsay E Nyhoff, Bridgette B Barron, Andrea Reboldi, and Peggy L Kendall

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BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein, Mohanraj Manangeeswaran, Derek D C Ireland, Seth G Thacker, Ha-Na Lee, Logan Kelley-Baker, Aaron P Lewkowicz, Paul W Rothlauf, Marjorie Cornejo Pontelli, Louis-Marie Bloyet, Michael A Eckhaus, Mirian I Mendoza, Sean Whelan, and Daniela Verthelyi

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Calorie restriction improves lipid-related emerging cardiometabolic risk factors in healthy adults without obesity: Distinct influences of BMI and sex from CALERIE™ a multicentre, phase 2, randomised controlled trial, Kim M Huffman, Susan B Racette, and et al.

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Cardiac immune cell infiltration associates with abnormal lipid metabolism, Vincenza Cifarelli, Ondrej Kuda, Kui Yang, Xinping Liu, Richard W Gross, Terri A Pietka, Gyu Seong Heo, Deborah Sultan, Hannah Luehmann, Josie Lesser, Morgan Ross, Ira J Goldberg, Robert J Gropler, Yongjian Liu, and Nada A Abumrad

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Case report: A novel EIF2B3 pathogenic variant in central nervous system hypomyelination/vanishing white matter, Parith Wongkittichote, Soe Soe Mar, Robert C McKinstry, and Hoanh Nguyen

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Case Report: "Primary immunodeficiency"-severe autoimmune enteropathy in a pediatric heart transplant recipient treated with abatacept and alemtuzumab, Elizaveta Kalaidina, Elizabeth C Utterson, Deepa Mokshagundam, Mai He, Shalini Shenoy, and Megan A Cooper

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Case report: Real-world experience using a personalized cancer-specific circulating tumor DNA assay in different metastatic melanoma scenarios, Karam Khaddour, Alice Zhou, Omar H Butt, Griffin Budde, Allyson Koyen Malashevich, and George Ansstas

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CD4+ T-lymphocytes exhibit biphasic kinetics post-myocardial infarction, Vinay Kumar, Sumanth D Prabhu, and Shyam S Bansal

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CDC20 regulates sensitivity to chemotherapy and radiation in glioblastoma stem cells, Diane D. Mao, Ryan T. Cleary, Amit Gujar, Tatenda Mahlokozera, and Albert H. Kim

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cGAS-STING pathway targeted therapies and their applications in the treatment of high-grade glioma, Shashwat Tripathi, Hinda Najem, Akanksha Sanjay Mahajan, Peng Zhang, Justin T Low, Alexander H Stegh, Michael A Curran, David M Ashley, Charles David James, and Amy B Heimberger

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Challenges and progress in research, diagnostics, and therapeutics in Alzheimer's disease and related dementias, Nikolay V Dokholyan, Richard C Mohs, and Randall J Bateman