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Submissions from 2022

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White matter abnormalities in the Hdc knockout mouse, a model of tic and OCD pathophysiology, Kantiya Jindachomthong, Chengran Yang, Yuegao Huang, Daniel Coman, Maximiliano Rapanelli, Fahmeed Hyder, Joseph Dougherty, Luciana Frick, and Christopher Pittenger

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White matter microstructure associations to amyloid burden in adults with Down syndrome, Austin M Bazydlo, Beau Ances, and et al

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WormBase in 2022-data, processes, and tools for analyzing Caenorhabditis elegans, Paul Davis, Tim Schedl, and et al

Submissions from 2021

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Impact of motile ciliopathies on human development and clinical consequences in the newborn, Rachael Hyland and Steven L. Brody

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Deep learning supplants visual analysis by experienced operators for the diagnosis of cardiac amyloidosis by cine-CMR, Philippe Germain, Armine Vardazaryan, Nicolas Padoy, Aissam Labani, Catherine Roy, Thomas Hellmut Schindler, and Soraya El Ghannudi

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Women and ethnoracial minorities with poor cardiovascular health measures associated with a higher risk of developing mood disorder, Aixia Guo, Kari A Stephens, Yosef M Khan, James R Langabeer, and Randi E Foraker

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Cerebral perfusion and sensory testing results differ in interstitial cystitis/bladder pain syndrome patients with and without fibromyalgia: A site-specific MAPP network study, Georg Deutsch, Hrishikesh Deshpande, H Henry Lai, Jason J Kutch, and Timothy J Ness

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Trial of spesolimab for generalized pustular psoriasis, Hervé Bachelez, Milan J Anadkat, and et al

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A next generation sequencing-based protocol for screening of variants of concern in autism spectrum disorder, Jie Huang, Jun Liu, Ruiyi Tian, Kevin Liu, Patrick Zhuang, Hannah Tayla Sherman, Christoph Budjan, Michelle Fong, Min-Seo Jeong, and Xue-Jun Kong

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CCR2 signaling restricts SARS-CoV-2 infection, Abigail Vanderheiden, Jeronay Thomas, Allison L Soung, Meredith E Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A Cowan, Kathryn Pellegrini, Pei-Yong Shi, Arash Grakoui, Robyn S Klein, Steven E Bosinger, Jacob E Kohlmeier, Vineet D Menachery, and Mehul S Suthar

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Myeloid-derived suppressor cells mediate T cell dysfunction in nonhuman primate TB granulomas, Bindu Singh, Dhiraj K Singh, Shashank R Ganatra, Ruby A Escobedo, Shabaana Khader, Larry S Schlesinger, Deepak Kaushal, and Smriti Mehra

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Rotavirus NSP1 contributes to intestinal viral replication, pathogenesis, and transmission, Gaopeng Hou, Qiru Zeng, Jelle Matthijnssens, Harry B Greenberg, and Siyuan Ding

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SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity, M Gordon Joyce, Rita E Chen, James Brett Case, Michael S Diamond, and et al

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Tricuspid valve intervention at the time of pulmonary valve replacement in adults with congenital heart disease: A systematic review and meta-analysis, Jef Van den Eynde, Connor P Callahan, Mauro Lo Rito, Nabil Hussein, Horacio Carvajal, Alvise Guariento, Arjang Ruhparwar, Alexander Weymann, Werner Budts, Marc Gewillig, Michel Pompeu Sá, and Shelby Kutty

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Emerging themes in the molecular pathogenesis of enterotoxigenic Escherichia coli, James M Fleckenstein and Alaullah Sheikh

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Impact of semi-annual albendazole on lymphatic filariasis and soil-transmitted helminth infection: Parasitological assessment after 14 rounds of community treatment, Sébastien D S Pion, Cédric B Chesnais, Gary J Weil, Frédéric Louya, Michel Boussinesq, and François Missamou

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The relationship between acute and chronic pancreatitis with pancreatic adenocarcinoma: Review, Tamara Alhobayb, Rahul Peravali, and Motaz Ashkar

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A protocol for the induction of experimental necrotizing enterocolitis in neonatal mice, Lila S Nolan, Qingqing Gong, Heather N Hofmeister, and Misty Good

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A review of DNA risk alleles to determine epigenetic repair of mRNA expression to prove therapeutic effectiveness in reward deficiency syndrome (RDS): Embracing "Precision Behavioral Management", Kenneth Blum, Bruce Steinberg, Marjorie C Gondre-Lewis, David Baron, Edward J Modestino, Rajendra D Badgaiyan, B William Downs, Debasis Bagchi, Raymond Brewer, Thomas McLaughlin, Abdalla Bowirrat, and Mark Gold

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Domain-specific biochemical and serological characterization of SARS-CoV-2 nucleocapsid protein, Chao Wu, Abraham J Qavi, Austin B Moyle, Nicole D Wagner, Asmaa Hachim, Niloufar Kavian, Aidan R Cole, Joyce Sweeney-Gibbons, Henry W Rohrs, J S Malik Peiris, Christopher F Basler, Michael L Gross, Sophie A Valkenburg, Christopher W Farnsworth, Gaya K Amarasinghe, and Daisy W Leung

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Human Achilles tendon mechanical behavior is more strongly related to collagen disorganization than advanced glycation end-products content, Jennifer A Zellers, Jeremy D Eekhoff, Remy E Walk, Mary K Hastings, Simon Y Tang, and Spencer P Lake

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Isolation of myeloid cells from mouse brain tumors for single-cell RNA-seq analysis, Mai T Dang, Fernanda Mafra, and Malay Haldar

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Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function, Karen Rosier, David J Pagliarini, and et al

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TIFAB accelerates MLL-AF9-induced acute myeloid leukemia through upregulation of HOXA9, Jinming Zhao, Yan Xiu, Lin Fu, Qianze Dong, Nicholas Borcherding, Yang Wang, Qingchang Li, Nilushi S De Silva, Ulf Klein, Brendan F Boyce, and Chen Zhao

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Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation, Stephen P Persaud, Julie K Ritchey, Sena Kim, Sora Lim, Peter G Ruminski, Matthew L Cooper, Michael P Rettig, Jaebok Choi, and John F DiPersio

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Minimally invasive postmortem intestinal tissue sampling in malnourished and acutely ill children is feasible and informative, Erika Feutz, Wieger Voskuijl, Peter J Finch, Ta-Chiang Liu, Robert H J Bandsma, Phillip I Tarr, Christopher Alan Moxon, Kelley VanBuskirk, Sarah Lawrence, Grace Umutesi, Kirkby D Tickell, James A Berkley, Judd L Walson, Steve Kamiza, and Donna M Denno

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Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers, Mark Yarchoan, Andrea Wang-Gillam, and et al

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STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks, Jogender Mehla, Itender Singh, Deepti Diwan, James W Nelson, Molly Lawrence, Eunjae Lee, Adam Q Bauer, David M Holtzman, and Gregory J Zipfel

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Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer, Xuxu Gou, Shunqiang Li, and et al.

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Utility of Facebook's social connectedness index in modeling COVID-19 spread: Exponential random graph modeling study, Beth Prusaczyk, Kathryn Pietka, Joshua M Landman, and Douglas A Luke

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Bleeding assessment tools in the diagnosis of VWD in adults and children: A systematic review and meta-analysis of test accuracy, Mohamad A. Kalot, Jorge Di Paola, and et al

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Early relapse identifies MCL patients with inferior survival after intensive or less intensive frontline therapy, David A. Bond, Mary-Kate Malecek, Brad S. Kahl, and et al

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Nanoparticles and photochemistry for native-like transmembrane protein footprinting, Jie Sun, Xiaoran Roger Liu, Shuang Li, Peng He, Weikai Li, and Michael L Gross

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Polatuzumab vedotin in previously untreated diffuse large B-cell lymphoma, Hervé Tilly, Neha Mehta-Shah, and et al

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Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis, Lianggong Ding, Wenfei Sun, Miroslav Balaz, Anyuan He, Manuel Klug, Stefan Wieland, Robert Caiazzo, Violeta Raverdy, Francois Pattou, Philippe Lefebvre, Irfan J Lodhi, Bart Staels, Markus Heim, and Christian Wolfrum

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Activation of the α1β2γ2L GABA receptor by physiological agonists, Spencer R Pierce, Allison L Germann, and Gustav Akk

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Axicabtagene ciloleucel as second-line therapy for large B-cell lymphoma, Frederick L Locke, Armin Ghobadi, and et al

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Genetics and molecular pathogenesis of human hydrocephalus, Maria Garcia-Bonilla, James P. McAllister, and David D. Limbrick

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Advancing pediatric antimicrobial stewardship: Has pharmacodynamic dosing for gram-negative infections taken effect?, Laura M. Puckett, Jason G. Newland, and Jennifer E. Girotto

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Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling, Samuel C Griffiths, Rebekka A Schwab, Kamel El Omari, Benjamin Bishop, Ellen J Iverson, Tomas Malinauskas, Ramin Dubey, Mingxing Qian, Douglas F Covey, Robert J C Gilbert, Rajat Rohatgi, and Christian Siebold

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Lyl-1 regulates primitive macrophages and microglia development, Shoutang Wang, Deshan Ren, Brahim Arkoun, Anna-Lila Kaushik, Gabriel Matherat, Yann Lécluse, Dominik Filipp, William Vainchenker, Hana Raslova, Isabelle Plo, and Isabelle Godin

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Regenerative responses of rabbit corneal endothelial cells to stimulation by fibroblast growth factor 1 (FGF1) derivatives, TTHX1001 and TTHX1114, Jessica Weant, David D Eveleth, Amuthakannan Subramaniam, Jennifer Jenkins-Eveleth, Michael Blaber, Ling Li, David M Ornitz, Asaf Alimardanov, Trevor Broadt, Hui Dong, Vinay Vyas, Xiaoyi Yang, and Ralph A Bradshaw

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Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia, Jit Chatterjee, Shilpa Sanapala, Olivia Cobb, Alice Bewley, Andrea K Goldstein, Elizabeth Cordell, Xia Ge, Joel R Garbow, Michael J Holtzman, and David H Gutmann

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Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes, Francesca Ferraro, Christopher A Miller, Keegan A Christensen, Nichole M Helton, Margaret O'Laughlin, Catrina C Fronick, Robert S Fulton, Jessica Kohlschmidt, Ann-Kathrin Eisfeld, Clara D Bloomfield, Sai Mukund Ramakrishnan, Ryan B Day, Lukas D Wartman, Geoffrey L Uy, John S Welch, Matthew J Christopher, Sharon E Heath, Jack D Baty, Matthew J Schuelke, Jacqueline E Payton, David H Spencer, Michael P Rettig, Daniel C Link, Matthew J Walter, Peter Westervelt, John F DiPersio, and Timothy J Ley

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Electronically available patient claims data improve models for comparing antibiotic use across hospitals: Results from 576 US facilities, Katherine E Goodman, Lisa Pineles, Laurence S Magder, Deverick J Anderson, Elizabeth Dodds Ashley, Ronald E Polk, Hude Quan, William E Trick, Keith F Woeltje, Surbhi Leekha, Sara E Cosgrove, and Anthony D Harris

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Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection, Nicholas Rinkenberger, Michael E Abrams, Sumit K Matta, John W Schoggins, Neal M Alto, and L David Sibley

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Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection, Nicholas Rinkenberger; Michael E. Abrams; Sumit K. Matta; John W. Schoggins; Neal M. Alto; and L, David Sibley

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High-throughput functional analysis of CFTR and other apically localized proteins in iPSC-derived human intestinal organoids, Sunny Xia, Zoltán Bozóky, Michelle Di Paola, Onofrio Laselva, Saumel Ahmadi, Jia Xin Jiang, Amy L Pitstick, Chong Jiang, Daniela Rotin, Christopher N Mayhew, Nicola L Jones, and Christine E Bear

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A deep learning framework identifies dimensional representations of Alzheimer's disease from brain structure, Zhijian Yang, Ilya M. Nasrallah, John C. Morris, and et al

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Gene dosage effects of poly(A) track-engineered hypomorphs, Geralle Powell, Slavica Pavlovic Djuranovic, and Sergej Djuranovic

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Social needs, chronic conditions, and health care utilization among Medicaid beneficiaries, Amy McQueen, Linda Li, Cynthia J. Herrick, Niko Verdecias, Derek S. Brown, Darrell J. Broussard, Rachel E. Smith, and Matthew Kreuter

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Using nasal povidone-iodine to prevent bloodstream infections and transmission of Staphylococcus aureus among haemodialysis patients: A stepped-wedge cluster randomised control trial protocol, Ana-Monica Racila, Amy O'Shea, Rajeshwari Nair, Kimberly Dukes, Loreen Herwaldt, Linda Boyken, Daniel Diekema, Melissa Ward, Jason Cobb, Jesse Jacob, David Pegues, Susan Bleasdale, Anitha Vijayan, Anubha Mutneja, Mony Fraer, Debra O'Connell-Moore, Pam Tolomeo, Minerva Mendez, Erin Jaworski, and Marin Schweizer

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A brief history of nearly EV-erything - The rise and rise of extracellular vesicles, Yvonne Couch, Edit I Buzàs, Dolores Di Vizio, Yong Song Gho, Paul Harrison, Andrew F Hill, Jan Lötvall, Graça Raposo, Philip D Stahl, Clotilde Théry, Kenneth W Witwer, and David R F Carter

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Access to and safety of COVID-19 convalescent plasma in the United States Expanded Access Program: A national registry study, Jonathon W. Senefeld, Brenda J. Grossman, and et al

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Adolescent Brain Cognitive Development (ABCD) Study Linked External Data (LED): Protocol and practices for geocoding and assignment of environmental data, Chun Chieh Fan, Andrew Marshall, Harry Smolker, Marybel R Gonzalez, Susan F Tapert, Deanna M Barch, Elizabeth Sowell, Gayathri J Dowling, Carlos Cardenas-Iniguez, Jessica Ross, Wesley K Thompson, and Megan M Herting

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A pilot study of urine proteomics in COVID-19-associated acute kidney injury, Yinyin Ye, Madhurima Kaushal, Diane Salamon, Amanda Knoten, Laura Marks, Joseph P Gaut, Anitha Vijayan, Philip A Mudd, Jane A O'Halloran, Sanjay Jain, and et al.

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Biochemical and immuno-histochemical localization of type IIA procollagen in annulus fibrosus of mature bovine intervertebral disc, Audrey McAlinden, David M Hudson, Aysel A Fernandes, Soumya Ravindran, and Russell J Fernandes

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Clinical and microbiological outcomes of ceftazidime-avibactam treatment in adults with Gram-negative bacteremia: A subset analysis from the phase 3 clinical trial program, John E Mazuski, Florian Wagenlehner, Antoni Torres, Yehuda Carmeli, Joseph W Chow, Dalia Wajsbrot, Gregory G Stone, Paurus Irani, David Bharucha, Karen Cheng, and Margaret Tawadrous

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Comparison of machine learning clustering algorithms for detecting heterogeneity of treatment effect in acute respiratory distress syndrome: A secondary analysis of three randomised controlled trials, Pratik Sinha, Alexandra Spicer, Kevin L Delucchi, Daniel F McAuley, Carolyn S Calfee, and Matthew M Churpek

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Compositional analysis of extracellular aggregates in the eyes of patients with exfoliation syndrome and exfoliation glaucoma, Alicia De Maria, Keith D Zientek, Larry L David, Phillip A Wilmarth, Anjali M Bhorade, George J Harocopos, Andrew J W Huang, Augustine R Hong, Carla J Siegfried, Linda M Tsai, Arsham Sheybani, and Steven Bassnett

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Corneal perforation in ocular graft-versus-host disease, Cathy Y Zhang, Asim V Farooq, George J Harocopos, Eric L Sollenberger, Joshua H Hou, Charles S Bouchard, Christine Shieh, Uyen L Tran, Anthony J Lubniewski, Andrew J W Huang, and Grace L Paley

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Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition, Amanda L Mohabeer, Jeffrey T Kroetsch, Meghan McFadden, Negin Khosraviani, Thomas J Broekelmann, Guangpei Hou, Hangjun Zhang, Yu-Qing Zhou, Minyao Wang, Anthony O Gramolini, Robert P Mecham, Scott P Heximer, Steffen-Sebastian Bolz, and Michelle P Bendeck

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Demographic and mental health assessments in the adolescent brain and cognitive development study: Updates and age-related trajectories, Deanna M Barch, Nicole R Karcher, and et al

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Detecting risk level in individuals misusing fentanyl utilizing posts from an online community on Reddit, Sanjana Garg, Jordan Taylor, Mai El Sherief, Erin Kasson, Talayeh Aledavood, Raven Riordan, Nina Kaiser, Patricia Cavazos-Rehg, and Munmun De Choudhury

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Development of a Qualified Clinical Data Registry for emergency medicine, Stephen K Epstein, Richard T Griffey, Michelle P Lin, James J Augustine, Pawan Goyal, and Arjun K Venkatesh

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Efficacy and safety of avapritinib in advanced systemic mastocytosis: Interim analysis of the phase 2 PATHFINDER trial, Jason Gotlib, Andreas Reiter, Stephen T Oh, and et al

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Emergency clinicians' perceptions of communication tools to establish the mental baseline of older adults: A qualitative study, Anita Chary, Christopher Joshi, Noelle Castilla-Ojo, Ilianna Santangelo, Kei Ouchi, Aanand D. Naik, Christopher R. Carpenter, Shan W Liu, and Maura Kennedy

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Fabrication and evaluation of bilateral Helmholtz radiofrequency coil for thermo-stable breast image with reduced artifacts, Young Han Lee, Kyu-Ho Song, Jaemoon Yang, Won Jun Kang, Keum Sil Lee, Min Jung Kim, Eun-Kyung Kim, Dan Heo, Bo-Young Choe, and Jin-Suck Suh

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From canines to humans: Clinical importance of Staphylococcus pseudintermedius, Karen C. Carroll, Carey-Ann D. Burnham, and Lars F. Westblade

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Genetic liability to cannabis use disorder and COVID-19 hospitalization, Alexander S Hatoum, Claire L Morrison, Sarah M C Colbert, Evan A Winiger, Emma C Johnson, Arpana Agrawal, and Ryan Bogdan

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How the value of the environment controls persistence in visual search, Michael R. Traner, Ethan S. Bromberg-Martin, and Ilya E. Monosov

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Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines, Susanna Nencetti, Doretta Cuffaro, Elisa Nuti, Lidia Ciccone, Armando Rossello, Marina Fabbi, Flavio Ballante, Gabriella Ortore, Grazia Carbotti, Francesco Campelli, Irene Banti, Rosaria Gangemi, Garland R Marshall, and Elisabetta Orlandini

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Increased mitochondrial activity upon CatSper channel activation is required for mouse sperm capacitation, Juan J Ferreira, Adriana Cassina, Pilar Irigoyen, Mariana Ford, Santiago Pietroroia, Nikita Peramsetty, Rafael Radi, Celia M Santi, and Rossana Sapiro

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Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: Exploratory phase 1 results in healthy volunteers, Frederico G S Toledo, William F Martin, Linda Morrow, Carine Beysen, Daiva Bajorunas, Ying Jiang, Bernard L Silverman, David McDonnell, Mark N Namchuk, John W Newcomer, and Christine Graham

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Investigating late-onset Pompe prevalence in neuromuscular medicine academic practices, Marie Wencel, Alan Pestronk, Julaine Florence, and et al

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Kinetic and structural mechanism for DNA unwinding by a non-hexameric helicase, Sean P. Carney, Wen Ma, Kevin D. Whitley, Haifeng Jia, Timothy M. Lohman, Zaida Luthey-Schulten, and Yann R. Chemla

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Long-term outcomes of primary cardiac malignant tumors: Difference between African American and Caucasian population, Quoc Bui, Tam N M Ngo, Jan Mazur, Vy Pham, Cassady Palmer, Binh Q Truong, Eugene S Chung, Huy G Vuong, and Vien T Truong

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Metastatic castrate-resistant prostate cancer: A rare cause of bowel obstruction, Syed Ehsanullah, Syeda Zarmeena Rashid, and Saiyed Abdullah A. Ehsanullah

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Minimizing the impact of the triple burden of COVID-19, tuberculosis and HIV on health services in sub-Saharan Africa, Jean B Nachega, Nathan Kapata, Nadia A Sam-Agudu, Eric H Decloedt, Patrick D M C Katoto, Tumaini Nagu, Peter Mwaba, Dorothy Yeboah-Manu, Pascalina Chanda-Kapata, Francine Ntoumi, Elvin H Geng, and Alimuddin Zumla

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Neutrophil extracellular trap inhibition increases inflammation, bacteraemia and mortality in murine necrotizing enterocolitis, Hala Chaaban, Kathryn Burge, Jeffrey Eckert, Ravi S Keshari, Robert Silasi, Cristina Lupu, Barbara Warner, Marilyn Escobedo, Michael Caplan, and Florea Lupu

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Ogden Type I to III tibial tubercle fractures in skeletally immature patients: Is routine anterior compartment fasciotomy of the leg indicated?, Corey Brown, Brian A. Kelly, Kirsten Brouillet, and Scott J. Luhmann

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Pharmacogenomics insights into precision pediatric oncology, Kristie N. Ramos, David Gregornik, and Kenneth S. Ramos

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Prediction of chronic postsurgical pain in adults: A protocol for multivariable prediciton model development, Nicholas Papadomanolakis-Pakis, Simon Haroutounian, Christian Christiansen, and Lone Nikolajsen

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Screening of severe acute respiratory syndrome coronavirus 2 RNA-dependent RNA Polymerase inhibitors using computational approach, Poonam Dhankhar, Vikram Dalal, and Viney Kumar

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Single-cell RNA-sequencing analysis of the ciliary epithelium and contiguous tissues in the mouse eye, J C Youkilis and S Bassnett

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Temporal evolution of the PcvCO2–PaCO2/CaO2–CcvO2 ratio vs serum lactate during resuscitation in septic shock, Shyam Madabhushi, Anjan Trikha, Rahul K. Anand, Rashmi Ramachandran, Preet M. Singh, and Vimi Rewari

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The Human Connectome Project: A retrospective, Jennifer Stine Elam, Matthew F. Glasser, Michael P. Harms, Gregory C. Burgess, Sandra W. Curtiss, Michael R. Hodge, Eileen A. Cler, Daniel M. Marcus, Deanna M. Barch, David C. Van Essen, and et al.

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Trajectory of emotion dysregulation in positive and negative affect across childhood predicts adolescent emotion dysregulation and overall functioning, Alecia C. Vogel, Rebecca Tillman, Nourhan M. El-Sayed, Joshua J. Jackson, Susan B. Perlman, Deanna M. Barch, and Joan L. Luby

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UNMASC: Tumor-only variant calling with unmatched normal controls, Paul Little, Heejoon Jo, Alan Hoyle, Angela Mazul, Xiaobei Zhao, Ashley H Salazar, Douglas Farquhar, Siddharth Sheth, Maheer Masood, Michele C Hayward, Joel S Parker, Katherine A Hoadley, Jose Zevallos, and D Neil Hayes

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Clustering of aromatic residues in prion-like domains can tune the formation, state, and organization of biomolecular condensates, Alex S Holehouse, Garrett M Ginell, Daniel Griffith, and Elvan Böke

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A reevaluation of the tolerability and effects of single-dose ivermectin treatment on Onchocerca volvulus microfilariae in the skin and eyes in eastern Ghana, Nicholas O Opoku, Michael E Gyasi, Felix Doe, Daphne Lew, Augustine R Hong, Sithembele Chithenga, Peter U Fischer, Christopher L King, and Gary J Weil

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Sex modifies APOE ε4 dose effect on brain tau deposition in cognitively impaired individuals, Shaozhen Yan, Chaojie Zheng, Manish D Paranjpe, Yanxiao Li, Weihua Li, Xiuying Wang, Tammie L S Benzinger, Jie Lu, and Yun Zhou

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A scoping review of de-implementation frameworks and models, Callie Walsh-Bailey, Edward Tsai, Rachel G Tabak, Alexandra B Morshed, Wynne E Norton, Virginia R McKay, Ross C Brownson, and Sheyna Gifford

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Identification of disease-linked hyperactivating mutations in UBE3A through large-scale functional variant analysis, Kellan P Weston, Xiaoyi Gao, Jinghan Zhao, Kwang-Soo Kim, Susan E Maloney, Jill Gotoff, Sumit Parikh, Yen-Chen Leu, Kuen-Phon Wu, Marwan Shinawi, Joshua P Steimel, Joseph S Harrison, and Jason J Yi

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Opening of a cryptic pocket in β-lactamase increases penicillinase activity, Catherine R Knoverek, Upasana L Mallimadugula, Sukrit Singh, Enrico Rennella, Thomas E Frederick, Tairan Yuwen, Shreya Raavicharla, Lewis E Kay, and Gregory R Bowman

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Impact of annual versus semiannual mass drug administration with ivermectin and albendazole on helminth infections in southeastern Liberia, Obiora A Eneanya, Lincoln Gankpala, Charles W Goss, Fatorma K Bolay, Gary J Weil, and Peter U Fischer

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Low-dose dobutamine cardiovascular magnetic resonance segmental strain study of early phase of intramyocardial hemorrhage rats, Rui Xia, Bo He, Tong Zhu, Yu Zhang, Yushu Chen, Lei Wang, Yang Zhou, Jichun Liao, Jie Zheng, Yongmei Li, Fajin Lv, and Fabao Gao

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A polygenic risk score predicts incident prostate cancer risk in older men but does not select for clinically significant disease, Andrew Bakshi, Yin Cao, and et al

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COVID-19 vaccine hesitancy and attitude toward booster doses among US healthcare workers, Suman Pal, Rahul Shekhar, Saket Kottewar, Shubhra Upadhyay, Mriganka Singh, Dola Pathak, Devika Kapuria, Eileen Barrett, and Abu Baker Sheikh

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SLO2.1/NALCN a sodium signaling complex that regulates uterine activity, Juan J Ferreira, Chinwendu Amazu, Lis C Puga-Molina, Xiaofeng Ma, Sarah K England, and Celia M Santi