Submissions from 2022
Self-esteem and weight status of young adults: Findings from a pilot study, Echu Liu and Su-Hsin Chang
Semaphorin-plexin signaling: From axonal guidance to a new X-linked intellectual disability syndrome, Jacqueline L Steele, Marwan S Shinawi, and et al.
Semi-quantitative assay to measure urease activity by urinary catheter-associated uropathogens, Jesus M Duran Ramirez, Jana Gomez, Chloe L P Obernuefemann, Nathaniel C Gualberto, and Jennifer N Walker
Sepsis prediction for the general ward setting, Sean C Yu, Aditi Gupta, Kevin D Betthauser, Patrick G Lyons, Albert M Lai, Marin H Kollef, Philip R O Payne, and Andrew P Michelson
Serologic and cytokine signatures in children with multisystem inflammatory syndrome and coronavirus disease 2019, Stacey A. Lapp, Carol M. Kao, David A. Hunstad, and et al
Severe ocrelizumab-induced enterocolitis treated successfully with ustekinumab, Janaki Shah, Ahmad Al-Taaee, Parakkal Deepak, and Anas Gremida
SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes through mitigation of oxidative and ER stress, Zeenat A. Shyr, Zihan Yan, Alessandro Ustione, Erin M. Egan, and Maria S. Remedi
Silver jubilee: 25 years of the first demonstration of the direct effect of phosphate on the parathyroid cell, Jordi Bover, Adriana Dusso, and et al.
Simulated cost-effectiveness and long-term clinical outcomes of addiction care and antibiotic therapy strategies for patients with injection drug use-associated infective endocarditis, Joëlla W. Adams, Alexandra Savinkina, James C. Hudspeth, Mam Jarra Gai, Raagini Jawa, Laura R. Marks, Benjamin P. Linas, Alison Hill, Jason Flood, Simeon Kimmel, and Joshua A. Barocas
Single-cell genomics for resolution of conserved bacterial genes and mobile genetic elements of the human intestinal microbiota using flow cytometry, Dylan Lawrence, Danielle E Campbell, Lawrence A Schriefer, Rachel Rodgers, Forrest C Walker, Marissa Turkin, Lindsay Droit, Miles Parkes, Scott A Handley, and Megan T Baldridge
Skeletal muscle contractile function in heart failure with reduced ejection fraction - A focus on nitric oxide, Lauren K Park, Andrew R Coggan, and Linda R Peterson
Socioecological model-based design and implementation principles of Lower Limb Preservation Programs as partners for Limb-loss Rehabilitation Programs- A mini-review, Vipul Khetarpaul, John P Kirby, Patrick Geraghty, John Felder, and Prateek Grover
Sonobiopsy for minimally invasive, spatiotemporally-controlled, and sensitive detection of glioblastoma-derived circulating tumor DNA, Christopher Pacia, Jinyun Yuan, Yimei Yue, Lu Xu, Arash Nazeri, Rupen Desai, H. Michael Gach, Xiaowei Wang, Michael Talcott, Aadel Chaudhuri, Gavin Dunn, Eric Leuthardt, and Hong Chen
STAT3 gain-of-function syndrome, Tiphanie P Vogel, Jennifer W Leiding, Megan A Cooper, and Lisa R Forbes Satter
Steroid hormone signaling activates thermal nociception during Drosophila peripheral nervous system development, Jacob S. Jaszczak, Laura DeVault, Lily Yeh Jan, and Yuh Nung Jan
Stigma towards mental illness and help-seeking behaviors among adult and child psychiatrists in Hungary: A cross-sectional study, Dorottya Őri, Péter Szocsics, Tamás Molnár, Fanni Virág Ralovich, Zsolt Huszár, Ágnes Bene, Sándor Rózsa, Zsuzsa Győrffy, and György Purebl
Subtyping of common complex diseases and disorders by integrating heterogeneous data. Identifying clusters among women with lower urinary tract symptoms in the LURN study, Victor P. Andreev, H Henry Lai, and et al
Survival after simultaneous pancreas-kidney transplantation in type 1 diabetes: The critical role of early pancreas allograft function, Mengmeng Ji, Mei Wang, Wenjun Hu, Mohamed Ibrahim, Krista L. Lentine, Massini Merzkani, Haris Murad, Yazen Al-Hosni, Ronald Parsons, Jason Wellen, Su-Hsin Chang, and Tarek Alhamad
Sustainability in pediatric hospitals: An exploration at the intersection of quality improvement and implementation science, Sara Malone, Jason Newland, Sapna R Kudchadkar, Kim Prewitt, Virginia McKay, Beth Prusaczyk, Enola Proctor, Ross C Brownson, and Douglas A Luke
SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence, J. Ignacio Gutierrez, Gregory P. Brittingham, Yonca Karadeniz, Kathleen D. Tran, Arnob Dutta, Alex S. Holehouse, Craig L. Peterson, and Liam J. Holt
Systematic review with meta-analysis: Safety and effectiveness of combining biologics and small molecules in inflammatory bowel disease, Quazim A Alayo, Osama Altayar, Matthew A Ciorba, Deborah Thomas, Parakkal Deepak, and et al.
Task modulation of single-neuron activity in the human amygdala and hippocampus, Runnan Cao, Alexander Todorov, Nicholas Brandmeir, and Shuo Wang
The 2021 FASEB science research conference on NAD metabolism and signaling, Vera Gorbunova, Shin-Ichiro Imai, and et al
The association of prescription opioid use with suicide attempts: An analysis of statewide medical claims data, Chongliang Luo, Kun Chen, Riddhi Doshi, Nathaniel Rickles, Yong Chen, Harold Schwartz, and Robert H. Aseltine
The burden of critical illness in hospitalized children in low- and middle-income countries: Protocol for a systematic review and meta-analysis, Teresa B Kortz, Kenneth E Remy, and et al.
The chasm in percutaneous coronary intervention and in-hospital mortality rates among acute myocardial infarction patients in rural and urban hospitals in China: A mediation analysis, Miao Cai, Echu Liu, Peng Bai, Nan Zhang, Siyu Wang, Wei Li, Hualiang Lin, and Xiaojun Lin
The enantiomer of allopregnanolone prevents pressure-mediated retinal degeneration via autophagy, Makoto Ishikawa, Toru Nakazawa, Hiroshi Kunikata, Kota Sato, Takeshi Yoshitomi, Kathiresan Krishnan, Douglas F Covey, Charles F Zorumski, and Yukitoshi Izumi
The first 20 months of the COVID-19 pandemic: Mortality, intubation and ICU rates among 104,590 patients hospitalized at 21 United States health systems, Michael C. Fiore, Li-Shiun Chen, and et al.
The future of AD clinical trials with the advent of anti-amyloid therapies: An CTAD Task Force report, J Delrieu, R J Bateman, J Touchon, M Sabbagh, and J Cummings
The human male liver is predisposed to inflammation via enhanced myeloid responses to inflammatory triggers, Adrian Kuipery, Deeqa Mahamed, Shirin Nkongolo, June Ann D'Angelo, Alexandra Johnson Valiente, Aman Mehrotra, William C Chapman, Peter Horton, Ian McGilvray, Harry L A Janssen, and Adam J Gehring
The impact of a virtual orthopaedic surgery symposium on medical students: Increasing awareness and knowledge of the field, Theodore Quan, Alex Gu, Amil R. Agarwal, Simone A. Bernstein, Alisa Malyavko, William N. Levine, Lisa K. Cannada, and Medical Student Orthopedic Society
The incidence of candidate binding sites for β-arrestin in Drosophila neuropeptide GPCRs, Paul H. Taghert
The influence of green space on obesity in China: A systematic review, Jing Shen, Mengfei Li, Qianhui Wang, Ruidong Liu, Mengmeng Ji, and Ruopeng An
The longitudinal impact of maternal depression and neighborhood social context on adolescent mental health, Daphne Lew, Hong Xian, Travis Loux, Enbal Shacham, and Darcell Scharff
The mobile sleep medicine model in neurologic practice: Rationale and application, Mark I Boulos, Luqi Chi, and Oleg Y Chernyshev
The Mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates, Lucie A. Bergeron, Tychele Turner, and et al
The past, present, and future of a human T-cell leukemia virus type 1 vaccine, Joshua J Tu, Victoria Maksimova, Lee Ratner, and Amanda R Panfil
The relevance of rich club regions for functional outcome post-stroke is enhanced in women, Anna K. Bonkhoff, Laura Heitsch, Chia-Ling Phuah, and et al.
The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia, Susan T Lubejko, Robert D Graham, Giulia Livrizzi, Robert Schaefer, Matthew R Banghart, and Meaghan C Creed
The role of neutrophil extracellular traps in acute lung injury, Davide Scozzi, Fuyi Liao, Alexander S Krupnick, Daniel Kreisel, and Andrew E Gelman
The temporal relationship between local school closure and increased incidence of pediatric diabetic ketoacidosis, Casey K McCluskey, Janine E Zee-Cheng, Margaret J Klein, Matthew C Scanlon, Alexandre T Rotta, Kenneth E Remy, Christopher L Carroll, and Steven L Shein
Top-down and bottom-up propagation of disease in the Neuronal Ceroid Lipofuscinoses, John R Ostergaard, Hemanth R Nelvagal, and Jonathan D Cooper
Totally percutaneous endovascular repair for ruptured abdominal aortic aneurysms, Shirli Tay, Mohamed S Zaghloul, Mehreen Shafqat, Chao Yang, Kshitij A Desai, Gayan De Silva, Luis A Sanchez, and Mohamed A Zayed
Tourette syndrome research highlights from 2020, Andreas Hartmann, Cyril Atkinson-Clement, Christel Depienne, and Kevin Black
Tourette syndrome research highlights from 2021, Andreas Hartmann, Per Andrén, Cyril Atkinson-Clement, Virginie Czernecki, Cécile Delorme, Nanette Marinette Debes, Natalia Szejko, Keisuke Ueda, and Kevin Black
Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model, Gerwin Schalk, Samuel Worrell, Filip Mivalt, Alexander Belsten, Inyong Kim, Jonathan M Morris, Dora Hermes, Bryan T Klassen, Nathan P Staff, Steven Messina, Timothy Kaufmann, Jörn Rickert, Peter Brunner, Gregory A Worrell, and Kai J Miller
Transition from cMyc to L-Myc during dendritic cell development coordinated by rising levels of IRF8, David A. Anderson, Feiya Ou, Sunkyung Kim, Theresa L. Murphy, and Kenneth M. Murphy
Treatment patterns and outcomes following disease progression on anti-PD-1 therapies for advanced melanoma, Beth L. Nordstrom, Melissa Hamilton, Jenna M. Collins, Dennis Earle, Ying Zhang, Shivani Srivastava, and Leonel Hernandez-Aya
Tumor lysis syndrome in a patient with metastatic endometrial cancer treated with lattice stereotactic body radiation therapy, Joshua P Schiff, Matthew B Spraker, Sai Duriseti, Sana Shaikh, Haris F Murad, David G Mutch, Clifford G Robinson, James Kavanaugh, and Alexander J Lin
Ultrasound-guided thrombin injection for the treatment of bleeding following kidney and liver biopsies, Mark J Hoegger and William D Middleton
Understanding and application of daptomycin-susceptible dose-dependent category for Enterococcus: A mixed-methods study, Jennifer L. Adema, Laurel N. Lake, Ryan W. Stevens, Breann M. Hogan, Audrey N. Schuetz, Aaron J. Tande, Kristin C. Mara, Allison R. Eberly, and Christina G. Rivera
Understanding contributors to racial and ethnic inequities in COVID-19 incidence and mortality rates, Karen E. Joynt Maddox, Mat Reidhead, Joshua Grotzinger, Timothy McBride, Aaloke Mody, Elna Nagasako, Will Ross, Joseph T. Steensma, and Abigail R. Barker
Understanding the contribution of metabolism to Mycobacterium tuberculosis drug tolerance, Amanda N Samuels, Erin R Wang, Gregory A Harrison, Joy C Valenta, and Christina L Stallings
Unique molecular identifier-based high-resolution HLA typing and transcript quantitation using long-read sequencing, Caleb Cornaby, Maureen C Montgomery, Chang Liu, and Eric T Weimer
Uric acid predicts recovery of left ventricular function and adverse events in heart failure with reduced ejection fraction: Potential mechanistic insight from network analyses, Xiqiang Wang, Xiude Fan, Qihui Wu, Jing Liu, Linyan Wei, Dandan Yang, Xiang Bu, Xiaoxiang Liu, Aiqun Ma, Tomohiro Hayashi, Gongchang Guan, Yu Xiang, Shuang Shi, Junkui Wang, and Jiansong Fang
Use of Implementation Mapping with community-based participatory research: Development of implementation strategies of a new goal setting and goal management intervention system, Eunyoung Kang and Erin R Foster
Use of Leishmania major parasites expressing a recombinant Trypanosoma cruzi antigen as live vaccines against Chagas disease, Catherine W Cai, Anne O'Shea, Christopher S Eickhoff, Hongjie Guo, Warren G Lewis, Stephen M Beverley, and Daniel F Hoft
Using Innovation-Corps (I-Corps™) methods to adapt a mobile health (mHealth) obesity treatment for community mental health settings, Rita Haddad, Carolina Badke D'Andrea, Amanda Ricchio, Bradley Evanoff, Elaine H Morrato, Joseph Parks, John W Newcomer, and Ginger E Nicol
Utility of using electrocardiogram measures of heart rate variability as a measure of cardiovascular autonomic neuropathy in type 1 diabetes patients, Rodica Pop-Busui, Jye-Yu C Backlund, Ionut Bebu, Barbara H Braffett, Gayle Lorenzi, Neil H White, John M Lachin, Elsayed Z Soliman, and DCCT/EDIC Research Group
Variation in ampicillin dosing for lower respiratory tract infections and neonatal bacterial infections in US children's hospitals, Elizabeth A Daniels, Christopher C McPherson, Jason G Newland, and Brian R Lee
Virtual adaptation of an international exchange program in medical education, Celia Fung, Nicholas Maxwell, Stephen Powell, Michelle Benassai, Natalia Chunga, Jennifer Corcoran, William Barbosa, Marisabel Lopez, Betsy Hanampa, Melissa Llaiqui-Condori, Victor Delgado-Lazo, Karina Mendoza, Yanet Astete, Martin Flor, Sheyla Palacios, Blanca Valdovinos, Jorge Risco, Isabel Camargo, Ralph Jozefowicz, and Karlo J Lizárraga
Visually guided respiratory motion management for Ethos adaptive radiotherapy, Taeho Kim, Zhen Ji, Benjamin Lewis, Eric Laugeman, Alex Price, Yao Hao, Geoffrey Hugo, Nels Knutson, Bin Cai, Hyun Kim, and Lauren Henke
Voting behavior during FDA Medical Device Advisory Committee panel meetings, Amanda Maisel-Campbell, Daniel I Schlessinger, Arianna F. Yanes, Emir Veledar, Kelly A. Reynolds, Sarah A. Ibrahim, Bianca Y. Kang, Noor Anvery, Emily Poon, and Murad Alam
Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease, Fuhai Li, Abdallah M Eteleeb, William Buchser, Christopher Sohn, Guoqiao Wang, Chengjie Xiong, Philip R Payne, Eric McDade, Celeste M Karch, Oscar Harari, and Carlos Cruchaga
What can Brinley plots tell us about cognitive aging? Exploring simulated data and modified Brinley plots, Jessica Nicosia, Emily R Cohen-Shikora, and Michael J Strube
What clonal hematopoiesis can teach us about MDS, Irenaeus C C Chan, Brian J Wiley, and Kelly L Bolton
What does it mean to be affiliated with care?: Delphi consensus on the definition of "unaffiliation" and "specialist" in sickle cell disease, Andrea E. Lamont, Lewis L. Hsu, Sara Jacobs, Robert Gibson, Marsha Treadwell, Yumei Chen, Richard Lottenberg, Kathleen Axelrod, Taniya Varughese, Cathy Melvin, Sharon Smith, Ifeanyi Beverly Chukwudozie, Julie Kanter, and Sickle Cell Disease Implementation Consortium
Where do T cell subsets stand in SARS-CoV-2 infection: An update, Mohammad Tarique, Mohd Suhail, Huma Naz, Naoshad Muhammad, Shams Tabrez, Torki A Zughaibi, Adel M Abuzenadah, Anwar M Hashem, Hari Shankar, Chaman Saini, and Alpana Sharma
White matter abnormalities in the Hdc knockout mouse, a model of tic and OCD pathophysiology, Kantiya Jindachomthong, Chengran Yang, Yuegao Huang, Daniel Coman, Maximiliano Rapanelli, Fahmeed Hyder, Joseph Dougherty, Luciana Frick, and Christopher Pittenger
White matter microstructure associations to amyloid burden in adults with Down syndrome, Austin M Bazydlo, Beau Ances, and et al
WormBase in 2022-data, processes, and tools for analyzing Caenorhabditis elegans, Paul Davis, Tim Schedl, and et al
Submissions from 2021
Impact of motile ciliopathies on human development and clinical consequences in the newborn, Rachael Hyland and Steven L. Brody
Deep learning supplants visual analysis by experienced operators for the diagnosis of cardiac amyloidosis by cine-CMR, Philippe Germain, Armine Vardazaryan, Nicolas Padoy, Aissam Labani, Catherine Roy, Thomas Hellmut Schindler, and Soraya El Ghannudi
Women and ethnoracial minorities with poor cardiovascular health measures associated with a higher risk of developing mood disorder, Aixia Guo, Kari A Stephens, Yosef M Khan, James R Langabeer, and Randi E Foraker
Cerebral perfusion and sensory testing results differ in interstitial cystitis/bladder pain syndrome patients with and without fibromyalgia: A site-specific MAPP network study, Georg Deutsch, Hrishikesh Deshpande, H Henry Lai, Jason J Kutch, and Timothy J Ness
Trial of spesolimab for generalized pustular psoriasis, Hervé Bachelez, Milan J Anadkat, and et al
A next generation sequencing-based protocol for screening of variants of concern in autism spectrum disorder, Jie Huang, Jun Liu, Ruiyi Tian, Kevin Liu, Patrick Zhuang, Hannah Tayla Sherman, Christoph Budjan, Michelle Fong, Min-Seo Jeong, and Xue-Jun Kong
CCR2 signaling restricts SARS-CoV-2 infection, Abigail Vanderheiden, Jeronay Thomas, Allison L Soung, Meredith E Davis-Gardner, Katharine Floyd, Fengzhi Jin, David A Cowan, Kathryn Pellegrini, Pei-Yong Shi, Arash Grakoui, Robyn S Klein, Steven E Bosinger, Jacob E Kohlmeier, Vineet D Menachery, and Mehul S Suthar
Myeloid-derived suppressor cells mediate T cell dysfunction in nonhuman primate TB granulomas, Bindu Singh, Dhiraj K Singh, Shashank R Ganatra, Ruby A Escobedo, Shabaana Khader, Larry S Schlesinger, Deepak Kaushal, and Smriti Mehra
Rotavirus NSP1 contributes to intestinal viral replication, pathogenesis, and transmission, Gaopeng Hou, Qiru Zeng, Jelle Matthijnssens, Harry B Greenberg, and Siyuan Ding
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity, M Gordon Joyce, Rita E Chen, James Brett Case, Michael S Diamond, and et al
Tricuspid valve intervention at the time of pulmonary valve replacement in adults with congenital heart disease: A systematic review and meta-analysis, Jef Van den Eynde, Connor P Callahan, Mauro Lo Rito, Nabil Hussein, Horacio Carvajal, Alvise Guariento, Arjang Ruhparwar, Alexander Weymann, Werner Budts, Marc Gewillig, Michel Pompeu Sá, and Shelby Kutty
Emerging themes in the molecular pathogenesis of enterotoxigenic Escherichia coli, James M Fleckenstein and Alaullah Sheikh
Impact of semi-annual albendazole on lymphatic filariasis and soil-transmitted helminth infection: Parasitological assessment after 14 rounds of community treatment, Sébastien D S Pion, Cédric B Chesnais, Gary J Weil, Frédéric Louya, Michel Boussinesq, and François Missamou
The relationship between acute and chronic pancreatitis with pancreatic adenocarcinoma: Review, Tamara Alhobayb, Rahul Peravali, and Motaz Ashkar
A protocol for the induction of experimental necrotizing enterocolitis in neonatal mice, Lila S Nolan, Qingqing Gong, Heather N Hofmeister, and Misty Good
A review of DNA risk alleles to determine epigenetic repair of mRNA expression to prove therapeutic effectiveness in reward deficiency syndrome (RDS): Embracing "Precision Behavioral Management", Kenneth Blum, Bruce Steinberg, Marjorie C Gondre-Lewis, David Baron, Edward J Modestino, Rajendra D Badgaiyan, B William Downs, Debasis Bagchi, Raymond Brewer, Thomas McLaughlin, Abdalla Bowirrat, and Mark Gold
Domain-specific biochemical and serological characterization of SARS-CoV-2 nucleocapsid protein, Chao Wu, Abraham J Qavi, Austin B Moyle, Nicole D Wagner, Asmaa Hachim, Niloufar Kavian, Aidan R Cole, Joyce Sweeney-Gibbons, Henry W Rohrs, J S Malik Peiris, Christopher F Basler, Michael L Gross, Sophie A Valkenburg, Christopher W Farnsworth, Gaya K Amarasinghe, and Daisy W Leung
Human Achilles tendon mechanical behavior is more strongly related to collagen disorganization than advanced glycation end-products content, Jennifer A Zellers, Jeremy D Eekhoff, Remy E Walk, Mary K Hastings, Simon Y Tang, and Spencer P Lake
Isolation of myeloid cells from mouse brain tumors for single-cell RNA-seq analysis, Mai T Dang, Fernanda Mafra, and Malay Haldar
Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function, Karen Rosier, David J Pagliarini, and et al
TIFAB accelerates MLL-AF9-induced acute myeloid leukemia through upregulation of HOXA9, Jinming Zhao, Yan Xiu, Lin Fu, Qianze Dong, Nicholas Borcherding, Yang Wang, Qingchang Li, Nilushi S De Silva, Ulf Klein, Brendan F Boyce, and Chen Zhao
Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation, Stephen P Persaud, Julie K Ritchey, Sena Kim, Sora Lim, Peter G Ruminski, Matthew L Cooper, Michael P Rettig, Jaebok Choi, and John F DiPersio
Minimally invasive postmortem intestinal tissue sampling in malnourished and acutely ill children is feasible and informative, Erika Feutz, Wieger Voskuijl, Peter J Finch, Ta-Chiang Liu, Robert H J Bandsma, Phillip I Tarr, Christopher Alan Moxon, Kelley VanBuskirk, Sarah Lawrence, Grace Umutesi, Kirkby D Tickell, James A Berkley, Judd L Walson, Steve Kamiza, and Donna M Denno
Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers, Mark Yarchoan, Andrea Wang-Gillam, and et al
STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks, Jogender Mehla, Itender Singh, Deepti Diwan, James W Nelson, Molly Lawrence, Eunjae Lee, Adam Q Bauer, David M Holtzman, and Gregory J Zipfel
Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer, Xuxu Gou, Shunqiang Li, and et al.
Utility of Facebook's social connectedness index in modeling COVID-19 spread: Exponential random graph modeling study, Beth Prusaczyk, Kathryn Pietka, Joshua M Landman, and Douglas A Luke
Bleeding assessment tools in the diagnosis of VWD in adults and children: A systematic review and meta-analysis of test accuracy, Mohamad A. Kalot, Jorge Di Paola, and et al