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Submissions from 2020

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Necrotizing soft tissue infections: A focused review of pathophysiology, diagnosis, operative management, antimicrobial therapy, and pediatrics, Jeffrey M. Tessier, James Sanders, Massimo Sartelli, Jan Ulrych, Belinda De Simone, Julia Grabowski, Sara Buckman, and Therese M. Duane

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Neighborhood socioeconomic deprivation associated with fat mass and weight status in youth, Morgan Clennin, Asia Brown, Min Lian, Marsha Dowda, Natalie Colabianchi, and Russell R Pate

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Neural networks to predict radiographic brain injury in pediatric patients treated with Extracorporeal Membrane Oxygenation, Neel Shah, Abdelaziz Farhat, Jefferson Tweed, Ziheng Wang, Jeon Lee, Rafe McBeth, Michael Skinner, Fenghua Tian, Ravi Thiagarajan, and Lakshmi Raman

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Neutron activation of gadolinium for ion therapy: A Monte Carlo study of charged particle beams, Kurt W. Van Delinder, Rao Khan, and James L. Gräfe

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Neutrophil L-plastin controls ocular paucibacteriality and susceptibility to keratitis, Xiaoxiao Lu, Abirami Kugadas, Kirsten Smith-Page, Jeffrey Lamb, Tiffany Lin, Yusha Ru, Sharon Celeste Morley, Raina Fichorova, Sharad K Mittal, Sunil K Chauhan, Sejiro Littleton, Daniel Saban, and Mihaela Gadjeva

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Neutrophil swarming delays the growth of clusters of pathogenic fungi, Alex Hopke, Allison Scherer, Samantha Kreuzburg, Michael S. Abers, Christa S. Zerbe, Mary C. Dinauer, Michael K. Mansour, and Daniel Irimia

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Newborn screening for Pompe disease in Illinois: Experience with 684,290 infants, Barbara K Burton, Joel Charrow, George E Hoganson, Julie Fleischer, Dorothy K Grange, Stephen R Braddock, Lauren Hitchins, Rachel Hickey, Katherine M Christensen, Daniel Groepper, Heather Shryock, Pamela Smith, Rong Shao, and Khaja Basheeruddin

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New imaging tools to measure nephron number in vivo: Opportunities for developmental nephrology, K M Bennett, E J Baldelomar, D Morozov, R L Chevalier, and J R Charlton

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Non-conventional treatments for conventional chondrosarcoma, Varun Monga, Hariharasudan Mani, Angela Hirbe, and Mohammed Milhem

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Nonmicrobial activation of TLRs controls intestinal growth, wound repair, and radioprotection, William F Stenson and Matthew A Ciorba

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Novel multimodal molecular imaging of Vitamin H (Biotin) transporter activity in the murine placenta, Ben Eliezer Noam, Lysenko Marina, Biton E. Inbal, Golani Ofra, Bartels L. Jennifer, Fernandez R. Solana, Aweda A. Tolulope, Clanton A. Nicholas, Beacham Rebecca, Lapi E. Suzanne, Garbow R. Joel, and Neeman Michal

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Nutrition in necrotizing enterocolitis and following intestinal resection, Jocelyn Ou, Cathleen M Courtney, Allie E Steinberger, Maria E Tecos, and Brad W Warner

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Obesity is a risk factor for acute promyelocytic leukemia: Evidence from population and cross-sectional studies and correlation with FLT3 mutations and polyunsaturated fatty acid metabolism, Luca Mazzarella, Timothy J. Ley, and et al.

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Oncologists’ communication and decision-making behaviors affect perceptions of sensitive information exchange for adolescent and young adult patients, Bryan A. Sisk, Karen Fasciano, Susan D. Block, and Jennifer W. Mack

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On complement, memory, and microglia, Robyn S. Klein

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Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity, Sebastiano Bariselli, Nanami L. Miyazaki, Meaghan C. Creed, and Alexxai V. Kravitz

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Orsay virus CP-δ adopts a novel β-bracelet structural fold and incorporates into virions as a head fiber, Yusong R. Guo, Yanlin Fan, Ying Zhou, Miao Jin, Jim L. Zhang, Hongbing Jiang, Matthew V. Holt, Tao Wang, Nicolas L. Young, David Wang, Weiwei Zhong, and Yizhi J. Tao

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Outcome of everolimus-based therapy in hormone-receptor-positive metastatic breast cancer patients after progression on palbociclib, Ajay Dhakal, Roby Antony Thomas, Ellis G. Levine, Adam Brufsky, Kazuaki Takabe, Matthew G. Hanna, Kristopher Attwood, Austin Miller, Thaer Khoury, Amy P. Early, Saif Soniwala, Tracy O'Connor, and Matuesz Opyrchal

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Pain relief after surgical decompression of the distal brachial plexus, Richard Morgan, Iain Elliot, Vibhu Banala, Christopher Dy, Briana Harris, and Elizabeth Anne Ouellette

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Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation, Cristiane de Oliveira, Mark E Lowe, and et al

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Parcel-guided rTMS for depression, M. Moreno Ortega, A. Kangarlu, S. Lee, T. Perera, J. Kangarlu, T. Palomo, M.F. Glasser, and D.C. Javitt

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Pathophysiological consequences of KATP channel overactivity and pharmacological response to glibenclamide in skeletal muscle of a murine model of Cantù syndrome, Rosa Scala, Fatima Maqoud, Nicola Zizzo, Antonietta Mele, Giulia Maria Camerino, Francesco Alfredo Zito, Girolamo Ranieri, Conor McClenaghan, Theresa M Harter, Colin G Nichols, and Domenico Tricarico

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Patient-controlled intravenous morphine analgesia combined with transcranial direct current stimulation for post-thoracotomy pain: A cost-effectiveness study and a feasibility for its future implementation, Nemanja Rancic, Katarina Mladenovic, Nela V Ilic, Viktorija Dragojevic-Simic, Menelaos Karanikolas, Tihomir V Ilic, and Dusica M Stamenkovic

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Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic gut-on-a-chip model, Kristen M. Seiler, Adam Bajinting, David M. Alvarado, Mahama A. Traore, Michael M. Binkley, William H. Goo, Wyatt E. Lanik, Jocelyn Ou, Usama Ismail, Micah Iticovici, Cristi R. King, Kelli L. VanDussen, Elzbieta A. Swietlicki, Vered Gazit, Jun Guo, Cliff J. Luke, Thaddeus Stappenbeck, Matthew A. Ciorba, Steven C. George, J. Mark Meacham, Deborah C. Rubin, Misty Good, and Brad W. Warner

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PD-L1 blockade in combination with inhibition of MAPK oncogenic signaling in patients with advanced melanoma, Antoni Ribas, Alain Algazi, Paolo A. Ascierto, Marcus O. Butler, Sunandana Chandra, Michael Gordon, Leonel Hernandez-Aya, Donald Lawrence, Jose Lutzky, Wilson H. Miller Jr., Katie M. Campbell, Bruno Delafont, Shannon Marshall, Nancy Mueller, and Caroline Robert

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Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship, Susan E Coffin, Stephanie Fritz, Jason Newland, and et al

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Pemphigus foliaceus in a patient with gastrointestinal stromal tumor treated with adjuvant imatinib mesylate, Hal A. Lewis, David Y. Chen, Ilana S. Rosman, Joel Picus, and Milan J. Anadkat

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Peptidoglycan editing provides immunity to Acinetobacter baumannii during bacterial warfare, Nguyen-Hung Le, Gisela Di Venanzio, Juvenal Lopez, Seth W Hennon, Mario F Feldman, and et al

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Performance of a multiplexed amplicon-based next-generation sequencing assay for HLA typing, Chang Liu, Brian F. Duffy, Eric T. Weimer, Maureen C. Montgomery, Jo-Ellen Jennemann, Rachel Hill, Donna Phelan, Lindsay Lay, and Bijal A. Parikh

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Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia, Peter L. Wang, Aldrin K. Y. Yim, Ki-Wook Kim, Denis Avey, Rafael S. Czepielewski, Marco Colonna, Jeffrey Milbrandt, and Gwendalyn J. Randolph

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Personality traits as markers of psychosis risk in Kenya: Assessment of temperament and character, Daniel Mamah, C Robert Cloninger, Victoria N Mutiso, Isaiah Gitonga, Albert Tele, and David M Ndetei

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Pharmacological inhibition of ataxia-telangiectasia mutated exacerbates acute kidney injury by activating p53 signaling in mice, Masahiro Uehara, Tetsuro Kusaba, Tomoharu Ida, Kunihiro Nakai, Tomohiro Nakata, Aya Tomita, Noriko Watanabe-Uehara, Kisho Ikeda, Takashi Kitani, Noriyuki Yamashita, Yuhei Kirita, Satoaki Matoba, Benjamin D. Humphreys, and Keiichi Tamagaki

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Phase 1–2 trial of antisense oligonucleotide tofersen for SOD1 ALS, Timothy Miller, Robert C. Bucelli, Alan Pestronk, and et al.

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Phase 2 study of ruxolitinib and decitabine in patients with myeloproliferative neoplasm in accelerated and blast phase, John O. Mascarenhas, Camille N. Abboud, and et al.

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Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002), Theodore Nicolaides, Karen Gauvain, and et al

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Photoreceptor responses to light in the pathogenesis of diabetic retinopathy, Shahriyar P Majidi and Rithwick Rajagopal

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Physician attitudes towards-and adoption of-mobile health, Tracie Kong, Mary Morgan Scott, Yang Li, and Cynthia Wichelman

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Pif1, RPA, and FEN1 modulate the ability of DNA polymerase δ to overcome protein barriers during DNA synthesis, Melanie A. Sparks, Peter M. Burgers, and Roberto Galletto

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PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor, Tigist Y. Tamir, David H. Drewry, Carrow Wells, M. Ben Major, and Alison D. Axtman

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Plasmacytoid dendritic cell impairment in metastatic melanoma by lactic acidosis, Matilde Monti, Raffaella Vescovi, Francesca Consoli, Davide Farina, Daniele Moratto, Alfredo Berruti, Claudia Specchia, and William Vermi

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Platelet α-granules are required for occlusive high-shear-rate thrombosis, Dongjune A. Kim, Katrina J. Ashworth, Jorge Di Paola, and David N. Ku

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Policies and practices of SHEA Research Network hospitals during the COVID-19 pandemic, Michael S Calderwood, Valerie M Deloney, Deverick J Anderson, Vincent Chi-Chung Cheng, Shruti Gohil, Jennie H Kwon, Lona Mody, Elizabeth Monsees, Valerie M Vaughn, Timothy L Wiemken, Matthew J Ziegler, and Eric Lofgren

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Polycystin 2 is increased in disease to protect against stress-induced cell death, Allison L. Brill, Tom T. Fischer, Jennifer M. Walters, Arnaud Marlier, Lorenzo R. Sewanan, Parker C. Wilson, Eric K. Johnson, Gilbert Moeckel, Lloyd G. Cantley, Stuart G. Campbell, Jeanne M. Nerbonne, Hee Jung Chung, Marie E. Robert, and Barbara E. Ehrlich

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Portal dosimetry scripting application programming interface (PDSAPI) for Winston-Lutz test employing ceramic balls, Yao Hao, Matthew C Schmidt, Yu Wu, and Nels C Knutson

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Positive allosteric modulation of CD11b as a novel therapeutic strategy against lung cancer, Terese Geraghty, Anugraha Rajagopalan, Rabail Aslam, Alexander Pohlman, Ishwarya Venkatesh, Andrew Zloza, David Cimbaluk, David G DeNardo, and Vineet Gupta

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Positron emission tomography objective parameters for assessment of left ventricular assist device infection using 18F-FDG PET/CT, Saul N Friedman, Maryam Mahmood, Jennifer R Geske, Muhammad Rizwan Sohail, Geoffrey B Johnson, John M Stulak, and Ayse Tuba Kendi

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Postdischarge antibiotic use for prophylaxis following spinal fusion, David K Warren, Katelin B Nickel, Jennifer H Han, Pam Tolomeo, Christopher J Hostler, Katherine Foy, Ian R Banks, Victoria J Fraser, Margaret A Olsen, and CDC Prevention Epicenter Program

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Postural directionality and head tremor in cervical dystonia, Qiyu Chen, Jeanne P Vu, Elizabeth Cisneros, Casey N Benadof, Zheng Zhang, Richard L Barbano, Christopher G Goetz, Joseph Jankovic, Hyder A Jinnah, Joel S Perlmutter, Mark I Appelbaum, Glenn T Stebbins, Cynthia L Comella, and David A Peterson

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Practitioner perspectives on building capacity for evidence-based public health in state health departments in the United States: A qualitative case study, Stephanie Mazzucca, Cheryl A Valko, Amy A Eyler, Marti Macchi, Andrew Lau, Jeanne Alongi, John Robitscher, and Ross C Brownson

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Pragmatic application of the RE-AIM framework to evaluate the implementation of tobacco cessation programs within NCI-Designated Cancer Centers, Heather D'Angelo, Alex T Ramsey, Li-Shiun Chen, and et al

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Precise breakpoint detection in a patient with 9p- syndrome, Jeffrey Ng, Eleanor Sams, Dustin Baldridge, Milinn Kremitzki, Daniel J Wegner, Tina Lindsay, Robert Fulton, F Sessions Cole, and Tychele N Turner

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Preclinical single photon emission computed tomography of alpha particle-emitting radium-223, Diane S. Abou, Andrew Rittenbach, Ryan E. Tomlinson, Paige A. Finley, Benjamin Tsui, Brian W. Simons, Abhinav K. Jha, David Ulmert, Ryan C. Riddle, and Daniel L. J. Thorek

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Predictive value of midtrimester universal cervical length screening based on parity, Joshua I. Rosenbloom, Nandini Raghuraman, Lorene A. Temming, Molly J. Stout, Methodius G. Tuuli, Jeffery M. Dicke, George A. Macones, and Alison G. Cahill

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Preemptive analgesic effect of intrathecal applications of neuroactive steroids in a rodent model of post-surgical pain: Evidence for the role of T-type calcium channels, Quy L Tat, Srdjan M Joksimovic, Kathiresan Krishnan, Douglas F Covey, Slobodan M Todorovic, and Vesna Jevtovic-Todorovic

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Prehospital use of a modified HEART Pathway and point-of-care troponin to predict cardiovascular events, Jason P. Stopyra, Louis Fornage, and et al.

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Prevalence of cryptococcal antigen and outcomes in people with human immunodeficiency virus in Honduras: A cohort study, Julio C. Zuniga-Moya, Jane A. O'Halloran, Andrej Spec, and et al

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Prevention and management of dermatologic adverse events associated with Tumor Treating Fields in patients with glioblastoma, Mario E Lacouture, Milan J Anadkat, Matthew T Ballo, Fabio Iwamoto, Suriya A Jeyapalan, Renato V La Rocca, Margaret Schwartz, Jennifer N Serventi, and Martin Glas

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Primary cilia as the nexus of biophysical and hedgehog signaling at the tendon enthesis, Fei Fang, Andrea G Schwartz, Emily R Moore, McKenzie E Sup, and Stavros Thomopoulos

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Primary cilia control glucose homeostasis via islet paracrine interactions, Jing W. Hughes, Jung Hoon Cho, Hannah E. Conway, Michael R. DiGruccio, Xue Wen Ng, Henry F. Roseman, Damien Abreu, Fumihiko Urano, and David W. Piston

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Proactive prevention: Act now to disrupt the impending non-communicable disease crisis in low-burden populations, Benson Njuguna, Angela Brown, Victor G. Davila-Roman, and et al.

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Professional decision-making in medicine: Development of a new measure and preliminary evidence of validity, Alison L. Antes, Kelly K. Dineen, Erin Bakanas, Tyler Zahrli, Jason D. Keune, Matthew J. Schuelke, and James M. DuBois

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Prognostic impact of CDKN2A/B deletion, TERT mutation, and EGFR amplification on histological and molecular IDH-wildtype glioblastoma, Sirui Ma, Soumon Rudra, Jian L Campian, Sonika Dahiya, Gavin P Dunn, Tanner Johanns, Michael Goldstein, Albert H Kim, and Jiayi Huang

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Promoting Undetectable equals Untransmittable in sub-Saharan Africa: Implication for clinical practice and ART adherence, Nicholas Ekow Thomford, Doreen Mhandire, Collet Dandara, and George B Kyei

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Prospective trial of sacroiliac joint fusion using 3D-printed Triangular titanium implants, Vikas Patel, Don Kovalsky, S Craig Meyer, Abhineet Chowdhary, Harry Lockstadt, Fernando Techy, Casey Langel, Robert Limoni, Philip S Yuan, Andy Kranenburg, Daniel Cher, Gabriel Tender, and Travis J Hillen

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Prostate cancer theranostics - An overview, Diane Abou, Nadia Benabdallah, Wen Jiang, Lu Peng, Hanwen Zhang, Alexandria Villmer, Mark S Longtine, and Daniel L J Thorek

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Protective and pathogenic effects of interferon signaling during pregnancy, Rebecca L. Casazza, Helen M. Lazear, and Jonathan J. Miner

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Protective role of brain derived neurotrophic factor (BDNF) in obstructive sleep apnea syndrome (OSAS) patients, Krisstopher Richard Flores, Fausta Viccaro, Mauro Aquilini, Stefania Scarpino, Francesco Ronchetti, Rita Mancini, Arianna Di Napoli, Davide Scozzi, and Alberto Ricci

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Proteomic resistance biomarkers for PI3K inhibitor in triple negative breast cancer patient-derived xenograft models, Zhanfang Guo, Tina Primeau, Jingqin Luo, Cynthia Zhang, Hua Sun, Jeremy Hoog, Feng Gao, Shixia Huang, Dean P Edwards, Sherri R Davies, Rebecca Aft, Li Ding, Matthew J Ellis, Shunqiang Li, and Cynthia X Ma

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Protocol for a proof-of-concept observational study evaluating the potential utility and acceptability of a telemedicine solution for the post-anesthesia care unit, Thaddeus P Budelier, Christopher Ryan King, Shreya Goswami, Anchal Bansal, Stephen H Gregory, Troy S Wildes, Joanna Abraham, Sherry L McKinnon, Amy Cooper, Ivan Kangrga, Jackie L Martin Jr., Melissa Milbrandt, Alex S Evers, and Michael S Avidan

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Quality of anticoagulation with warfarin in rural Chhattisgarh, India, Puja Chebrolu, Sushil Patil, Timothy S. Laux, Noor Al-Hammadi, Yogesh Jain, and Brian Gage

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Quality of life with second or third line nab-paclitaxel-based regimens in advanced non-small-cell lung cancer, Santiago Ponce Aix, Ramaswamy Govindan, Daniel Morgensztern, and et al

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Quantitative cardiac magnetic resonance T2 imaging offers ability to non-invasively predict acute allograft rejection in children, Neeta Sethi, Ashish Doshi, Tina Doshi, Russell Cross, Ileen Cronin, Elena Amin, Joshua Kanter, Janet Scheel, Sairah Khan, Adrienne Campbell-Washburn, and Laura Olivieri

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Quantitative definition of neurobehavior, vision, hearing and brain volumes in macaques congenitally exposed to Zika virus, Michelle R. Koenig, Kevin Noguchi, and et al.

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Race- and gender-based differences in descriptions of applicants in the letters of recommendation for orthopaedic surgery residency, Alexa Powers, Katherine M. Gerull, Rachel Rothman, Sandra A. Klein, Rick W. Wright, and Christopher J. Dy

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Racial and ethnic differences in parental decision-making roles in pediatric oncology, Bryan A. Sisk, Tammy I. Kang, and Jennifer W. Mack

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Radiation and checkpoint inhibitor immunotherapy lead to long term disease control in a metastatic RCC patient with brain metastases, Maria Levitin, Joel Ofori, Woo Jae Shin, Jiayi Huang, Mackenzie Daly, Dengfeng Cao, and Russell Pachynski

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Radically open dialectical behavior therapy: Social signaling, transdiagnostic utility and current evidence, Kirsten Gilbert, Karyn Hall, and R Trent Codd

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Radiolabeled 6-(2, 3-dichlorophenyl)-N4-methylpyrimidine-2, 4-diamine (TH287): A potential radiotracer for measuring and imaging MTH1, Huaping Chen, Sadia Afrin, Yingqiu Guo, Wenhua Chu, Tammie L S Benzinger, Buck E Rogers, Joel R Garbow, Joel S Perlmutter, Dong Zhou, and Jinbin Xu

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Randomized controlled crossover trials of the pharmacokinetics of PRC-063, a novel multilayer extended-release formulation of methylphenidate, in healthy adults, Martin A. Katzman, Greg Mattingly, Larry J. Klassen, Marc J. Cataldo, and Graeme A. E. Donnelly

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Randomized, double-blind, placebo-controlled, flexible-dose titration study of methylphenidate hydrochloride extended-release capsules (Aptensio XR) in preschool children with attention-deficit/hyperactivity disorder, Ann C. Childress, Scott H. Kollins, Henry C. Foehl, Jeffrey H. Newcorn, Greg Mattingly, Robert J. Kupper, and Akwete L. Adjei

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Rapid determination of internal strains in soft tissues using an experimentally calibrated finite element model derived from magnetic resonance imaging, Dong Hwan E. Yoon, Christian I. Weber, Garrett W. D. Easson, Kaitlyn S. Broz, and Simon Y. Tang

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Rates of brain atrophy across disease stages in familial frontotemporal dementia associated with MAPT, GRN, and C9orf72 pathogenic variants, Adam M. Staffaroni, Nupur Ghoshal, and et al

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Reaching consensus on principles of stakeholder engagement in research, Melody S. Goodman, Nicole Ackermann, Deborah J. Bowen, members of the Delphi panel, and Vetta Sanders Thompson

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Real-time colorectal cancer diagnosis using PR-OCT with deep learning, Yifeng Zeng, Shiqi Xu, William C. Chapman Jr., Shuying Li, Zahra Alipour, Heba Abdelal, Deyali Chatterjee, Matthew Mutch, and Quing Zhu

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Reassessing rabbit antithymocyte globulin induction in kidney transplantation (RETHINK): An analysis of the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) registry, Isa F. Ashoor, Karen Martz, Shirley Galbiati, Robbie A. Beyl, Vikas R. Dharnidharka, and NAPRTCS Investigators

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Reconstruction of severe palm injury with sensate medial plantar artery flap and nerve grafting, William M. Padovano, Elspeth J.R. Hill, and John M. Felder III

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Redox systems biology: Harnessing the sentinels of the cysteine redoxome, Jason M. Held

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Reduced expression of cerebral metabotropic glutamate receptor subtype 5 in men with fragile X syndrome, James R Brašić, Ayon Nandi, David S Russell, Danna Jennings, Olivier Barret, Anil Mathur, Keith Slifer, Thomas Sedlak, Samuel D Martin, Zabecca Brinson, Pankhuri Vyas, John P Seibyl, Elizabeth M Berry-Kravis, Dean F Wong, and Dejan B Budimirovic

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Reduced intensity conditioning for acute myeloid leukemia using melphalan- vs busulfan-based regimens: A CIBMTR report, Zheng Zhou, Geoffrey L. Uy, and et al.

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Refined National Institutes of Health response algorithm for chronic graft-versus-host disease in joints and fascia, Yoshihiro Inamoto, Stephanie J. Lee, Lynn E. Onstad, Mary E.D. Flowers, Betty K. Hamilton, Madan H. Jagasia, Paul J. Martin, Steven Z. Pavletic, Joseph A. Pidala, Iskra Pusic, Georgia B. Vogelsang, Daniel Wolff, and Paul A. Carpenter

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Regulation of epithelial-mesenchymal transition and organoid morphogenesis by a novel TGFβ-TCF7L2 isoform-specific signaling pathway, Kunal Karve, Stuart Netherton, Lili Deng, Azad Bonni, and Shirin Bonni

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Regulation of signaling and metabolism by lipin-mediated phosphatidic acid phosphohydrolase activity, Andrew J Lutkewitte and Brian N Finck

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Regulatory T cells developing peri-weaning are continually required to restrain Th2 systemic responses later in life, Kathryn A. Knoop, Keely G McDonald, Chyi-Song Hsieh, Phillip I Tarr, and Rodney D Newberry

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Relations between sensory responsiveness and features of autism in children, Jacob I Feldman, Margaret Cassidy, Yupeng Liu, Anne V Kirby, Mark T Wallace, and Tiffany G Woynaroski

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Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline, D L Tudorascu, C M Laymon, M Zammit, D S Minhas, S J Anderson, P A Ellison, S Zaman, B M Ances, M Sabbagh, S C Johnson, C A Mathis, W E Klunk, B L Handen, B T Christian, and A D Cohen

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Relationships between big-five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease, Andrew J Aschenbrenner, Jennifer Petros, Eric McDade, Guoqiao Wang, David A Balota, Tammie LS Benzinger, Carlos Cruchaga, Chengjie Xiong, Richard Perrin, Anne M Fagan, John C Morris, Randall Bateman, Jason Hassenstab, and et al

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Remethylation of Dnmt3a−/− hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing, Shamika Ketkar, Angela M. Verdoni, Amanda M. Smith, Celia V. Bangert, Elizabeth R. Leight, David Y. Chen, Meryl K. Brune, Nichole M. Helton, Mieke Hoock, Daniel R. George, Catrina Fronick, Robert S. Fulton, Sai Mukund Ramakrishnan, Gue Su Chang, Allegra A. Petti, David H. Spencer, Christopher A. Miller, and Timothy J. Ley

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Reporting guidelines, review of methodological standards, and challenges toward harmonization in bone marrow adiposity research. Report of the Methodologies Working Group of the International Bone Marrow Adiposity Society, Josefine Tratwal, Erica L Scheller, and et al

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Residual endotoxin induces primary graft dysfunction through ischemia/reperfusion-primed alveolar macrophages, Mahzad Akbarpour, Daniel Kreisel, Wenjun Li, and et al

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Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples, Matthew H. Bailey, William U. Meyerson, Lewis Jonathan Dursi, Liang-Bo Wang, Guanlan Dong, Wen-Wei Liang, Amila Weerasinghe, Shantao Li, Sean Kelso, MC3 Working Group, PCAWG novel somatic mutation calling methods working group, Gordon Saksena, Kyle Ellrott, Michael C. Wendl, David A. Wheeler, Gad Getz, Jared T. Simpson, Mark B. Gerstein, Li Ding, and PCAWG Consortium