The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2015
A genetically modified adenoviral vector with a phage display-derived peptide incorporated into fiber fibritin chimera prolongs survival in experimental glioma, Julius W. Kim, J. Robert Kane, Jacob S. Young, Alan L. Chang, Deepak Kanojia, Ramin A. Morshed, Jason Miska, Atique U. Ahmed, Irina V. Balyasnikova, Yu Han, Lingjiao Zhang, David T. Curiel, and Maciej S. Lesniak
An excitatory amacrine cell detects object motion and provides feature-selective input to ganglion cells in the mouse retina, Tahnbee Kim, Florentina Soto, and Daniel Kerschensteiner
Distinct transcriptomic features are associated with transitional and mature B-cell populations in the mouse spleen, Eden Kleiman, Daria Salyakina, Magali De Heusch, Kristen L. Hoek, Joan M. Llanes, Iris Castro, Jacqueline A. Wright, Emily S. Clark, Derek M. Dykxhoorn, Enrico Capobianco, Akiko Takeda, Ryan M. McCormack, Eckhard R. Podack, Jean-Christophe Renauld, and Wasif N. Khan
Interventions to slow aging in humans: Are we ready?, Samuel Klein and et al
Maternal obesity and rectovaginal group B streptococcus colonization at term, Shelby M. Kleweis, Alison G. Cahill, Anthony O. Odibo, and Methodius G. Tuuli
Comparing expert reported outcomes to national surgical quality improvement program risk calculator-predicted outcomes: Do reporting standards differ?, B. A. Knight, Aaron M. Protretzke, Jeffrey A. Larson, and Sam B. Bhayani
Missouri mothers and their children: A family study of the effects of genetics and the prenatal environment, Valerie S. Knopik, Andrew C. Heath, Kristine Marceau, Rohan H C Palmer, John E. McGeary, Alexandre Todorov, and Allison S. Evans
Regulation of yeast DNA polymerase δ-mediated strand displacement synthesis by 5'-flaps, Katrina N. Koc, Joseph L. Stodola, Peter M. Burgers, and Roberto Galletto
Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9, Anat Kohn, Timothy P. Rutkowski, Zhaoyang Liu, Anthony J. Mirando, Michael J. Zuscik, Regis J. O'Keefe, and Matthew J. Hilton
Moving from capstones toward cornerstones: Successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders, Nathan Kopp, Sharlee Climer, and Joseph D. Dougherty
NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells, Rama P. Kotipatruni, Xuan Ren, Dinesh Thotala, and Jerry J. Jaboin
Ribosomes slide on lysine-encoding homopolymeric A stretches., Kristin S. Koutmou, Anthony P. Schuller, Julie L. Brunelle, Aditya Radhakrishnan, Sergej Djuranovic, and Rachel Green
Analysis of the role of the C-terminal tail in the regulation of the epidermal growth factor receptor, Erika Kovacs, Rahul Das, Qi Wang, Timothy S. Collier, Aaron Cantor, Yongjian Huang, Kathryn Wong, Amar Mirza, Tiago Barros, Patricia Grob, Natalia Jura, Ron Bose, and John Kuriyan
Diastolic function in heart failure, Sándor J. Kovács
The glucose transporter PfHT1 is an antimalarial target of the HIV protease inhibitor lopinavir, Thomas E. Kraft, Christopher Armstrong, Monique R. Heitmeier, Audrey R. Odom, and Paul W. Hruz
Hookah-related Twitter chatter: A content analysis, Melissa J. Krauss, Shaina J. Sowles, Megan Moreno, Kidist Zewdie, Richard A. Grucza, Laura J. Beirut, and Patricia A. Cavazos-Rehg
Cortical alpha activity predicts the confidence in an impending action, Jan Kubanek, N. Jeremy Hill, Lawrence H. Snyder, and Gerwin Schalk
Cognitive and action-based aspects of developing decisions in parietal cortex, Jan Kubanek and Eric Mooshagian
Matching behavior as a tradeoff between reward maximization and demands on neural computation, Jan Kubanek and Lawrence H. Snyder
Reward-based decision signals in parietal cortex are partially embodied, Jan Kubanek and Lawrence H. Snyder
Agitation down-regulates immunoglobulin binding protein EibG expression in Shiga toxin-producing Escherichia coli (STEC), Thorsten Kuczius, Wenlan Zhang, Viktor Merkel, Alexander Mellmann, Phillip I. Tarr, and Helge Karch
Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining, Vandna Kukshal, In-Kwon Kim, Gregory L. Hura, Alan E. Tomkinson, John A. Tainer, and Tom Ellenberger
Trade-offs in the effects of the apolipoprotein E polymorphism on risks of diseases of the heart, cancer, and neurodegenerative disorders: Insights on mechanisms from the long life family study, Alexander M. Kulminski, Konstantin G. Arbeev, Irina Culminskaya, Svetlana V. Ukraintseva, Eric Stallard, Michael A. Province, and Anatoli I. Yashin
Awareness of the association between obesity and peri-operative risk among newly diagnosed patients with complex atypical hyperplasia and endometrial cancer, Lindsay M. Kuroki, Teri E. Benn, Jonathan L. Dukes, Andrea R. Hagemann, Premal H. Thaker, Matthew A. Powell, David G. Mutch, L. Stewart Massad, and Israel Zighelboim
Randomized controlled trial to determine the impact of probiotic administration on colonization with multidrug-resistant organisms in critically ill patients, Jennie H. Kwon, Kerry M. Bommarito, Kimberly A. Reske, Sondra M. Seiler, Tiffany Hink, Hilary M. Babcock, Marin H. Kollef, Victoria J. Fraser, Carey-Ann D. Burnham, and Erik R. Dubberke
Correlation between psychological stress levels and the severity of overactive bladder symptoms, Henry Lai, Vivien Gardner, Joel Vetter, and Gerald L. Andriole
Restriction of dietary protein decreases mTORC1 in tumors and somatic tissues of a tumor-bearing mouse xenograft model, Dudley W. Lamming, Nicole E. Cummings, Antonella L. Rastelli, Feng Gao, Edda Cava, Beatrice Bertozzi, Francesco Spelta, Roberto Pili, and Luigi Fontana
Phenotypic variation Is almost entirely independent of the host-pathogen relationship in clinical isolates of S. aureus, Adrian D. Land, Patrick Hogan, Stephanie Fritz, and Petra Anne Levin
CARMIL2 is a novel molecular connection between vimentin and actin essential for cell migration and invadopodia formation, Hunter M. Lanier, Taekyung Kim, and John A. Cooper
Chloride–hydrogen antiporters ClC‐3 and ClC‐5 drive osteoblast mineralization and regulate fine‐structure bone patterning in vitro, Quitterie C. Larrouture, Deborah J. Nelson, Lisa J. Robinson, Li Liu, Irina Tourkova, Paul H. Schlesinger, and Harry C. Blair
Nonmodifiable factors and complications contribute to length of stay in robot-assisted partial nephrectomy, Jeffrey A. Larson, Jihad H. Kaouk, Michael D. Stifelman, Craig G. Rogers, Mohamad E. Allaf, Aaron Potretzke, Susan Marshall, Homayoun Zargar, Mark W. Ball, and Sam B. Bhayani
Long-term neural and physiological phenotyping of a single human, Timothy O. Laumann, Evan Gordon, Abraham Z. Snyder, Babatunde Adeyemo, Steven E. Petersen, and et al
De novo assembly and transcriptome analysis of Plasmodium gallinaceum identifies the Rh5 interacting protein (ripr), and reveals a lack of EBL and RH gene family diversification, Elvin J. Lauron, Han Xian Aw Yeang, Samantha M. Taffner, and Ravinder N.M. Sehgal
Dialysis enrollment patterns in Guatemala: Evidence of the chronic kidney disease of non-traditional causes epidemic in Mesoamerica, Timothy S. Laux, Joaquin Barnoya, Douglas R. Guerrero, and Marcos Rothstein
The Relevance of the Colon to Zinc Nutrition, Geetha Lavaniya Gopalsamy, David H. Alpers, Henry J. Binder, Cuong D. Tran, B. S. Ramakrishna, Ian Brown, Mark Manary, Elissa Mortimer, and Graeme P. Young
Concomitant Cox-Maze IV techniques during mitral valve surgery, Christopher P. Lawrance, Matthew C. Henn, and Ralph J. Damiano Jr.
IgG4-associated orbital and ocular inflammation, Cecilia S. Lee, George J. Harocopos, Courtney L. Kraus, Aaron Y. Lee, Gregory P. Van Stavern, Steven M. Couch, and P. Kumar Rao
Lack of neuroinflammation in the HIV-1 transgenic rat: An [18 F]-DPA714 PET imaging study, Dianne E. Lee, Xuyi Yue, Wael G. Ibrahim, Margaret R. Lentz, Kristin L. Peterson, Elaine M. Jagoda, Michael Kassiou, Dragan Maric, William C. Reid, and Dima A. Hammoud
Development of an ex vivo model for the study of cerebrovascular function utilizing isolated mouse olfactory artery, Hyung-Jin Lee, Hans H. Dietrich, Byung Hee Han, and Gregory J. Zipfel
Developmental enhancers revealed by extensive DNA methylome maps of zebrafish early embryos, Hyung Joo Lee, Rebecca F. Lowdon, Brett Maricque, Bo Zhang, Michael Stevens, Daofeng Li, Stephen L. Johnson, and Ting Wang
Eisosome ultrastructure and evolution in fungi, microalgae, and lichens, Jae-Hyeok Lee, John E. Heuser, Robyn Roth, and Ursula Goodenough
The association of parental temperament and character on their children’s behavior problems, Soo Jin Lee, C. Robert Cloninger, Soo Hyun Park, and Han Chae
Pulmonary Function Following Adult Spinal Deformity Surgery: Minimum Two-Year Follow-up, Ronald A. Lehman Jr., Daniel G. Kang, Lawrence G. Lenke, Jeremy J. Stallbaumer, and Brenda A. Sides
Long-term safety and efficacy of antithymocyte globulin induction: Use of integrated national registry data to achieve ten-year follow-up of 10-10 Study participants, Krista L. Lentine, Mark A. Schnitzler, Huiling Xiao, and Daniel C. Brennan
Drug metabolizing enzyme and transporter gene variation, nicotine metabolism, prospective abstinence, and cigarette consumption, Christina N. Lessov-Schlaggar and et al.
ORegAnno 3.0: A community-driven resource for curated regulatory annotation, Robert Lesurf, Kelsy C. Cotto, Grace Wang, Malachi Griffith, Katayoon Kasaian, Steven J M Jones, Stephen B. Montgomery, Obi L. Griffith, and The Open Regulatory Annotation Consortium
An intrinsically disordered peptide from Ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions, Daisy Leung, Jennifer M. Binning, Gai Liu, Ian B. Harvey, Juanli Pan, Gaya K. Amarasinghe, and et al
Effects of CD2-associated protein deficiency on amyloid-β in neuroblastoma cells and in an APP transgenic mouse model, Fan Liao, Hong Jiang, Subhashini Srivatsan, Qingli Xiao, Katheryn B. Lefton, Kaoru Yamada, Thomas E. Mahan, Jin-Moo Lee, Andrey S. Shaw, and David M. Holtzman
Murine versus human apolipoprotein E4: Differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models, Fan Liao, Tony J. Zhang, Hong Jiang, Katheryn B. Lefton, Grace O. Robinson, Robert Vassar, Patrick M. Sullivan, and David M. Holtman
Head position change is not associated with acute changes in bilateral cerebral oxygenation in stable preterm infants during the first 3 days of life, Steve Ming-Che Liao, Rakesh Rao, and Amit M. Mathur
Expression of five acetylcholine receptor subunit genes in Brugia malayi adult worms, Ben-Wen Li, Amy C. Rush, and Gary J. Weil
Genetic heterogeneity of induced pluripotent stem cells: Results from 24 clones derived from a single C57BL/6 mouse, Cheng Li, Jeffery M. Klco, Nichole M. Helton, Daniel R. George, Jacqueline L. Mudd, Christopher A. Miller, Charles Lu, Robert Fulton, Michelle O'Laughlin, Catrina Fronick, Richard K. Wilson, and Timothy J. Ley
Species-specific transmission of novel picornaviruses in lemurs, Efrem S. Lim, Sharon L. Deem, Ingrid J. Porton, Song Cao, and David Wang
Role of hypoxia inducible factor-1α (HIF-1α) in innate defense against uropathogenic Escherichia coli infection, Ann E. Lin, Federico C. Beasley, Joshua Olson, Nadia Keller, Robert A. Shalwitz, Thomas J. Hannan, Scott J. Hultgren, and Victor Nizet
Molecular dynamics simulations of KirBac1.1 mutants reveal global gating changes of Kir channels, Tobias Linder, Shizhen Wang, Eva-Maria Zangerl-Plessl, Colin G Nichols, and Anna Stary-Weinzinger
A NIMA-related kinase suppresses the flagellar instability associated with the loss of multiple axonemal structures, Huawen Lin, Zhengyan Zhang, Suyang Guo, Fan Chen, Jonathan M. Kessler, Yan Mei Wang, and Susan K. Dutcher
Plasma biomarker of dietary phytosterol intake, Xiaobo Lin, Susan B. Racette, Lina Ma, Michael Wallendorf, Catherine Anderson Spearie, and Richard E. Ostlund Jr.
Novel APC promoter and exon 1B deletion and allelic silencing in three mutation-negative classic familial adenomatous polyposis families, Yiing Lin, Shin Lin, Melanie D. Baxter, Lawrence Lin, Susan M. Kennedy, Zhengyan Zhang, Paul J. Goodfellow, William C. Chapman, and Nicholas O. Davidson
In vivo evaluation of adipose-derived stromal cells delivered with a nanofiber scaffold for tendon-to-bone repair, Justin Lipner, Hua Shen, Leonardo Cavinatto, Wenying Liu, Necat Havlioglu, Younan Xia, Leesa M. Galatz, and Stavros Thomopoulos
Complement regulator CD46: Genetic variants and disease associations, M. Kathryn Liszewski and John P. Atkinson
Influence of model boundary conditions on blood flow patterns in a patient specific stenotic right coronary artery, Biyue Liu, Jie Zheng, Richard Bach, and Dalin Tang
Phosphorylation of the BNIP3 C-terminus inhibits mitochondrial damage and cell death without blocking autophagy, Katherine E. Liu and William A. Frazier
Pirt contributes to uterine contraction‑induced pain in mice, Qin Liu and et al
Assessing computational steps for CLIP-seq data analysis, Qi Liu, Xue Zhong, Blair B. Madison, Anil K. Rustgi, and Yu Shyr
Vasohibin-1 suppresses colon cancer, Shuai Liu, Bing Han, Qunyuan Zhang, Jie Dou, Fang Wang, Wenli Lin, Yuping Sun, and Guangyong Peng
Interring gas dynamic analysis of piston in a diesel engine considering the thermal effect, Wanyou Li, Yibin Guo, Tao He, Xiqun Lu, and Dequan Zou
Diagnostic accuracy of the iCare rebound tonometer compared to the Perkins applanation tonometer in assessing intraocular pressure in rural patients, Yifan Li, Christopher R. Carpenter, Kathryn Nicholson, and William K. Milne
SATB2 is a sensitive marker for lower gastrointestinal well-differentiated neuroendocrine tumors, Zhongwu Li, Jing Yuan, Lixin Wei, Kaiyong Mei, Junqiu Yue, Hongwen Gao, Miao Zhang, Ling Jia, Qiang Kang, Xiaozheng Huang, and Dengfeng Cao
A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors, A. Craig Lockhart and et al
Performance assessment of a NaI(Tl) gamma counter for PET applications with methods for improved quantitative accuracy and greater standardization, Martin A. Lodge, Daniel P. Holt, Paul E. Kinahan, Dean F. Wong, and Richard L. Wahl
Using knowledge exchange to build and sustain community support to reduce cancer screening inequities, Aisha Lofters, Tazim Virani, Gurpeet Grewal, and Rebecca Lobb
GABAB encephalitis: A fifty-two-year-old man with seizures, dysautonomia, and acute heart failure, Matthew C. Loftspring, Eric Landsness, Lindsey Wooliscroft, Robert Rudock, Sally Jo, and Kevin R. Patel
The DEK oncoprotein is a critical component of the EKLF/KLF1 enhancer in erythroid cells, Felix Lohmann, Mohan Dangeti, Shefali Soni, Xiaoyong Chen, Antanas Planutis, Margaret H. Baron, Kyunghee Choi, and James J. Bieker
A cost-effective junior resident training and assessment simulator for orthopaedic surgical skills via Fundamentals of Orthopaedic Surgery, Gregory Lopez, Rick Wright, David Martin, James Jung, Daniel Bracey, and Ranjan Gupta
Host-like carbohydrates promote bloodstream survival of Vibrio vulnificus in vivo, Jean-Bernard Lubin, Warren G. Lewis, Nicole M. Gilbert, Cory M. Weimer, Salvador Almagro-Moreno, E. F. Boyd, and Amanda L. Lewis
The Interferon-stimulated gene Ifi27l2a restricts West Nile virus infection and pathogenesis in a cell-type and region-specific manner, Tiffany M. Lucas, Justin M. Richner, and Michael S. Diamond
An integrated multi-study analysis of intra-subject variability in cerebrospinal fluid amyloid-β concentrations collected by lumbar puncture and indwelling lumbar catheter, Brendan P. Lucey, Randall J. Bateman, and et al
Patterns and functional implications of rare germline variants across 12 cancer types, Charles Lu, Mingchao Xie, Michael C. Wendl, Jiayin Wang, Michael D. McLellan, Kuan-lin Huang, Matthew A. Wyczalkowski, Reyka Jayasinghe, Jie Ning, Piyush Tripathi, Qunyuan Zhang, Beifang Niu, Kai Ye, Heather K. Schmidt, Robert S. Fulton, Joshua F. McMichael, Prag Batra, Cyriac Kandoth, Maheetha Bharadwaj, Daniel C. Koboldt, Christopher A. Miller, Krishna L. Kanchi, James M. Eldred, David E. Larson, John S. Welch, Bradley A. Ozenberger, Ramaswamy Govindan, Matthew J. Walter, Matthew J. Ellis, Elaine R. Mardis, Timothy A. Graubert, John F. Dipersio, Timothy J. Ley, Richard K. Wilson, Feng Chen, and Li Ding
Orbital causes of incomitant strabismus, Gregg T. Lueder
Conservation and immunogenicity of novel antigens in diverse isolates of enterotoxigenic Escherichia coli, Qingwei Luo, Firdausi Qadri, Rita Kansal, David A. Rasko, Alaullah Sheikh, and James M. Fleckenstein
Accurate and efficient target prediction using a potency-sensitive influence-relevance voter, Alessandro Lusci, Michael Browning, David Fooshee, Joshua Swamidass, and Pierre Baldi
Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis, Priya Luthra, David S. Jordan, Daisy W. Leung, Gaya K. Amarasinghe, and Christopher F. Basler
Effect of chronic administration of low dose rapamycin on development and immunity in young rats, Zhenya Lu, Furong Liu, Linglin Chen, Huadan Zhang, Yuemin Ding, Jianziang Liu, Michael Wong, and Ling-Hui Zeng
Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo, Shannon L. Macauley, Molly Stanley, Emiley E. Caesar, Steven A. Yamada, Marcus E. Raichle, Ronaldo Perez, Thomas E. Mahan, Courtney L. Stuphen, and David M. Holtzman
Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection, Donna A. MacDuff, Tiffany A. Reese, Jacqueline M. Kimmey, Leslie A. Weiss, Christina Song, Xin Zhang, Amal Kambal, Erning Duan, Javier A. Carrero, Marco Colonna, Brian T. Edelson, L David Sibley, Christina L. Stallings, Herbert W. Virgin, and et al
Exome sequencing identifies a missense variant in EFEMP1 co-segregating in a family with autosomal dominant primary open-angle glaucoma, Donna S. Mackay, Thomas M. Bennett, and Alan Shiels
D-cycloserine to enhance extinction of cue-elicited craving for alcohol: A translational approach, J MacKillop, L R. Few, M K. Stojek, C M. Murphy, S F. Malutinok, F T. Johnson, S G. Hofmann, J E. McGeary, R M. Swift, and P M. Monti
Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence, P Madden, N L. Saccone, and et al
Let-7 represses carcinogenesis and a stem cell phenotype in the intestine via regulation of Hmga2, Blair B. Madison, Arjun N. Jeganathan, Rei Mizuno, Monte M. Winslow, Antoni Castells, Miriam Cuatrecasas, and Anil K. Rustgi
The dynamic genome and transcriptome of the human fungal pathogen Blastomyces and close relative Emmonsia, Vincent Magrini, Makedonka Mitreva, Elaine R. Mardis, and et al.
Model-driven mapping of transcriptional networks reveals the circuitry and dynamics of virulence regulation, Ezekiel J. Maier, Brian C. Haynes, Stacey R. Gish, Zhuo A. Wang, Michael L. Skowyra, Alyssa L. Marulli, Tamara L. Doering, and Michael R. Brent
RIG-I signaling Is essential for influenza B virus-induced rapid interferon gene expression, Sanna M. Makela, Pamela Osterlund, Veera Westenius, Sinikka Latvala, Michael S. Diamond, Michael Gale Jr., and Ilkka Julkunen
Ploidy-Seq: Inferring mutational chronology by sequencing polyploid tumor subpopulations, Ankit Malhotra, Yong Wang, Jill Waters, Ken Chen, Funda Meric-Bernstam, Ira M. Hall, and Nicholas E. Navin
A reminder of methylene blue's effectiveness in treating vasoplegic syndrome after on-pump cardiac surgery, Joshua Manghelli, Lisa Brown, Hany B. Tadros, and Nabil A. Munfakh
Mucosally transplanted mesenchymal stem cells stimulate intestinal healing by promoting angiogenesis, Nicholas A. Manieri, Madison R. Mack, Molly D. Himmelrich, Daniel L. Worthley, Elaine M. Hanson, Lars Eckmann, Timothy C. Wang, and Thaddeus S. Stappenbeck
Adipose-derived mesenchymal stromal cells modulate tendon fibroblast responses to macrophage-induced inflammation in vitro, Cionne N. Manning, Catherine Martel, Shelly E. Sakiyama-Elbert, Matthew J. Silva, Shivam Shah, Richard H. Gelberman, and Stavros Thomopoulous
A CDC20-APC/SOX2 signaling axis regulates human glioblastoma stem-like cells, Diane D. Mao, Amit D. Gujar, Tatenda Mahlokozera, Ishita Chen, Yanchun Pan, Jingqin Luo, Tayler Brost, Elizabeth A. Thompson, Alice Turski, Eric C. Leuthardt, Gavin P. Dunn, Michael R. Chicoine, Keith M. Rich, Joshua L. Dowling, Gregory J. Zipfel, Ralph G. Dacey, Samuel Achilefu, David D. Tran, Hiroko Yano, and Albert H. Kim
Case report: brown fat accumulation of Tc-99m macroaggregated albumin in a lung perfusion study in a patient with multiple lung arteriovenous malformations and right-to-left shunting, Wael Marashdeh and Richard L. Wahl
Cancer Genomics, Elaine Mardis
Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children, Elaine Mardis, Robert Fulton, and et al.
