The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2015
Secreted CLCA1 modulates TMEM16A to activate Ca2+-dependent chloride currents in human cells, Monica Sala-Rabanal, Zeynep Yurtsever, Colin G. Nichols, and Tom J. Brett
Non-alcoholic steatohepatitis: Pathogenesis and clinical management, Federico Salomone, Shira Zelber-Sagi, Fabio Galvano, and Elisa Fabbrini
Use of culturally focused theoretical frameworks for adapting diabetes prevention programs: A qualitative review, Vetta L. Sanders Thompson, Michelle Johnson-Jennings, Ana A. Baumann, and Enola Proctor
Dual processing of sulfated steroids in the olfactory system of an anuran amphibian, Alredo Sansone, Thomas Hassenklover, Thomas Offner, Xiaoyan Fu, Timothy E. Holy, and Ivan Manzini
Are movement disorders and sensorimotor injuries pathologic synergies? When normal multi-joint movement synergies become pathologic, Marco Santello and Catherine E. Lang
A single protein S-acyl transferase acts through diverse substrates to determine cryptococcal morphology, stress tolerance, and pathogenic outcome, Felipe H. Santiago-Tirado, Tao Peng, Meng Yang, Howard C. Hang, and Tamara L. Doering
Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior, Ignacio Sarria, Johan Pahlberg, Yan Cao, Alexander V. Kolesnikov, Vladimir J. Kefalov, Alapakkam P. Sampath, and Kirill A. Martemyanov
Architectural and biochemical adaptations in skeletal muscle and bone following rotator cuff injury in a rat model, Eugene J. Sato, Megan L. Killian, Anthony J. Choi, Evie Lin, Alexander D. Choo, Ana E. Rodriguez-Soto, Chanteak T. Lim, Stavros Thomopoulos, Leesa M. Galatz, and Samuel R. Ward
Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene, mimics age-associated changes in sleep quality and adiposity, Akiko Satoh, Cynthia S. Brace, Nick Rensing, and Shin-ichiro Imai
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites, Daniel Savic, Brian S. Roberts, Julia B. Carleton, E. Christopher Partridge, Michael A. White, Barak A. Cohen, Gregory M. Cooper, Jason Gertz, and Richard M. Myers
Whole body melanoma transcriptome response in medaka, Manfred Schartl, Yingjia Shen, Katja Maurus, Ron Walter, Chad Tomlinson, Richard K. Wilson, John Postlethwait, and Wesley C. Warren
WormBase 2016: Expanding to enable helminth genomic research, Tim Schedl and et al
Nab-paclitaxel-based compared to docetaxel-based induction chemotherapy regimens for locally advanced squamous cell carcinoma of the head and neck, Amy Schell, Jessica Ley, Ningying Wu, Kathryn Trinkaus, Tanya Marya Wildes, Loren Michel, Wade Thorstad, Hiram Gay, James Lewis, Jason Rich, Jason Diaz, Randal C. Paniello, Brian Nussenbaum, and Douglas R. Adkins
Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues, Erica L. Scheller and et al.
The mitochondria in diabetic heart failure: From pathogenesis to therapeutic promise, Joel D. Schilling
Autosomal dominant Alzheimer disease: A unique resource to study CSF biomarker changes in preclinical AD, Suzanne Elizabeth Schindler and Anne M. Fagan
Photo-activatable Cre recombinase regulates gene expression in vivo, Suzanne E. Schindler, Jordan G. McCall, Ping Yan, Krzysztof L. Hyrc, Mingjie Li, Chandra L. Tucker, Jin-Moo Lee, Michael R. Bruchas, and Marc I. Diamond
The utility of Google Trends data to examine interest in cancer screening, Mario Schootman, Aroona H. Toor, Patricia A. Cavazos-Rehg, Donna B. Jeffe, Amy McQueen, J. Eberth, and Nicholas O. Davidson
Uropathogenic Escherichia coli superinfection enhances the severity of mouse bladder infection, Drew J. Schwartz, Matt S. Conover, Thomas J. Hannan, and Scott J. Hultgren
Patterns of gene conversion in duplicated yeast histones suggest strong selection on a coadapted macromolecular complex, Kathy Scienski, Justin C. Fay, and Gavin C. Conant
A noncanonical autophagy pathway restricts Toxoplasma gondii growth in a strain-specific manner in IFN-γ-activated human cells, Elizabeth M. Selleck, Robert C. Orchard, Kara G. Lassen, Wandy L. Beatty, Ramnik J. Xavier, Beth Levine, Herbert W. Virgin, and L. David Sibley
Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions, Rajarshi Sengupta, Amy Barone, Jayne Marasa, Sara Taylor, Erin Jackson, Nicole M. Warrington, Shyam Rao, Albert H. Kim, Jeffrey R. Leonard, David Piwnica-Worms, and Joshua B. Rubin
REDHORSE-REcombination and Double crossover detection in Haploid Organisms using next-geneRation SEquencing data, Jahangheer S. Shaik, Asis Khan, Stephen M. Beverley, and L. David Sibley
Perivascular arrest of CD8+ T cells is a signature of experimental cerebral malaria, Tovah N. Shaw, Phillip J. Stewart-Hutchinson, Patrick Strangward, Durga B. Dandamudi, Jonathan A. Coles, Ana Villega-Mendez, Julio Gallego-Delgado, Nico van Rooijen, Egor Zindy, Ana Rodriguez, James M. Brewer, Kevin N. Couper, and Michael L. Dustin
Voluntary exercise training: Analysis of mice in uninjured, inflammatory, and nerve-injured pain states, Tyler D. Sheahan, Bryan A. Copits, Judith P. Golden, and Robert W. Gereau IV
Selective blockade of interferon-α and -β reveals their non-redundant functions in a mouse model of West Nile virus infection, Kathleen C. F. Sheehan, Helen M. Lazear, Michael S. Diamond, and Robert D. Schreiber
Clinical applications of next generation sequencing in cancer: From panels, to exomes, to genomes, Tony Shen, Stefan Hans Pajaro-Van de Stadt, Nai Chien Yeat, and Jimmy C.-H. Lin
Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157: H7 against fatal systemic intoxication, Abhineet S. Sheoran, Igor P. Dmitriev, Elena A. Kashentseva, Ocean Cohen, Jean Mukherjee, Michelle Debatis, Jonathan Schearer, Jacqueline M. Tremblay, Gillian Beamer, David T. Curiel, Charles B. Shoemaker, and Saul Tzipori
Prognostic capabilities of coronary computed tomographic angiography before non-cardiac surgery: Prospective cohort study, Tej Sheth, Matthew Chan, Craig Butler, Benjamin Chow, Vikas Tandon, Peter Nagele, Ayesha Mitha, Marko Mrkobrada, Wojciech Szczeklik, Yang Faridah, Bruce Biccard, Lori K. Stewart, Diane Heels-Ansdell, P. J. Devereaux, and Coronary Computed Tomographic Angiography and Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (Coronary CTA VISION) Study Investigators
The future of glaucoma surgery, Arsham Sheybani
Dynamic changes in the subgingival microbiome and their potential for diagnosis and prognosis of periodontitis, Baochen Shi, Michaela Chang, John Martin, Makedonka Mitreva, Renate Lux, Perry Klokkevold, Erica Sodergren, George M. Weinstock, Susan K. Haake, and Huiying Li
Outcomes associated with bacteremia in the setting of methicillin-resistant Staphylococcus aureus pneumonia: A retrospective cohort study, Andrew F. Shorr, Marya D. Zilberberg, Scott T. Micek, and Marin H. Kollef
Impact of a structured review session on medical student psychiatry subject examination performance, Shan H. Siddiqi, Kevin J. Black, and Fay Y. Womer
Orthostatic stability with intravenous levodopa, Shan H. Siddiqi, Mary L. Creech, and Kevin J. Black
WU polyomavirus in respiratory epithelial cells from lung transplant patient with job syndrome, Erica A. Siebrasse, Nang L. Nguyen, Annie Wang, David Wang, Diana V. Pastrana, Mark J. Roth, Steven M. Holland, Alexandra F. Freeman, Christopher B. Buck, and John McDyer
Deconvoluting heme biosynthesis to target blood-stage malaria parasites, Paul A. Sigala, Jan R. Crowley, Jeffrey P. Henderson, and Daniel E. Goldberg
A simple transfer function for nonlinear dendritic integration, Matthew F. Singh and David H. Zald
Immune checkpoints and immunotherapy for colorectal cancer, Preet Paul Singh, Piyush K. Sharma, Gayathri Krishnan, and A. Craig Lockhart
Optodynamic simulation of β-adrenergic receptor signalling, Edward R. Siuda, Jordan G. McCall, Ream Al-Hasani, Gunchul Shin, Sung Il Park, Martin J. Schmidt, Sonya L. Anderson, William J. Planer, John A. Rogers, and Michael R. Bruchas
Clinical effectiveness of a sedation protocol minimizing benzodiazepine infusions and favoring early dexmedetomidine: A before-after study, Lee P. Skrupky, Anne M. Drewry, Brian Wessman, R. Ryan Field, Richard E. Fagley, Linda Varghese, Angela Lieu, Joshua Olatunde, Scott T. Micek, Marin H. Kollef, and Walter A. Boyle
Temperatures achieved in human and canine neocortex during intraoperative passive or active focal cooling, Matthew D. Smyth, Rowland H. Han, Chester K. Yarbrough, Edward E. Patterson, Xiao-Feng Yang, John W. Miller, Steven M. Rothman, and Raimondo D'Ambrosio
Development and verification of the PAM50-based Prosigna breast cancer gene signature assay, Jacqueline Snider, Tammi Vickery, Sherri R. Davies, Elaine R. Mardis, and et al
Increasing the reliability of fully automated surveillance for central line–associated bloodstream infections, Rachael E. Snyders, Ashleigh J. Goris, Kathleen A. Gase, Carole L. Leone, Joshua A. Doherty, and Keith F. Woeltje
Loss of local astrocyte support disrupts action potential propagation and glutamate release synchrony from unmyelinated hippocampal axon terminals in vitro, Courtney Sobieski, Xiaoping Jiang, Devon C. Crawford, and Steven Mennerick
Primary prevention of sudden cardiac death in adults with transposition of the great arteries: A review of implantable cardioverter-defibrillator placement, Sandeep S. Sodhi and Ari M. Cedars
RNA sequencing of tumor-associated microglia reveals Ccl5 as a stromal chemokine critical for neurofibromatosis-1 glioma growth, Anna C. Solga, Winnie W. Pong, Keun-Young Kim, Patrick J. Cimino, Joseph A. Toonen, Jason Walker, Todd Wylie, Vincent Magrini, Malachi Griffith, Obi L. Griffith, Amy Ly, Mark H. Ellisman, Elaine R. Mardis, and David H. Gutmann
Unique and redundant functions of NKp46+ ILC3s in models of intestinal inflammation, Christina Song, Jacob S. Lee, Susan Gilfillan, Michelle L. Robinette, Rodney D. Newberry, Thaddeus S. Stappenbeck, Matthias Mack, Marina Cella, and Marco Colonna
A case of squamous cell carcinoma of the skin due to the molecularly confirmed Lynch Syndrome, Steven Sorscher
Synaptic remodeling of neuronal circuits in early retinal degeneration, Florentina Soto and Daniel Kerschensteiner
End-stage liver disease Is a strong predictor of early mortality in cryptococcosis, Andrej Spec, Krunal Raval, and William G. Powderly
Protection against experimental Cryptococcosis following vaccination with glucan particles containing Cryptococcus alkaline extracts, Charles A. Specht, Chrono K. Lee, Haibin Huang, Donald J. Tipper, Zu T. Shen, Jennifer K. Lodge, John Leszyk, Gary R. Ostroff, and Stuart M. Levitz
Exome sequencing for mucolipidosis III: Detection of a novel GNPTAB gene mutation in a patient with a very mild phenotype, F. Sperb-Ludwig, T. Alegra, R. V. Velho, N. Ludwig, C. A. Kim, F. Kok, J. P. Kitajima, E. van Meel, S. Kornfeld, M. G. Burin, and I. V.D. Schwartz
Precision medicine to improve use of bleeding avoidance strategies and reduce bleeding in patients undergoing percutaneous coronary intervention: Prospective cohort study before and after implementation of personalized bleeding risks, John A. Spertus, Carole Decker, Elizabeth Gialde, Philip G. Jones, Edward J. McNulty, Richard Bach, and Adnan K. Chhatriwalla
The malaria parasite cation ATPase PfATP4 and its role in the mechanism of action of a new arsenal of antimalarial drugs, Natalie Jane Spillman and Kiaran Kirk
Exome sequencing of case-unaffected-parents trios reveals recessive and de novo genetic variants in sporadic ALS, Karyn Meltz Steinberg, Bing Yu, Daniel C. Koboldt, Elaine R. Mardis, and Roger Pamphlett
Burden of disease variants in participants of the Long Life Family Study, Meredith Stevenson, Harold Bae, Nicole Schupf, Stacy Andersen, Qunyuan Zhang, Thomas Perls, and Paola Sebastiani
Additive global cerebral blood flow normalization in arterial spin labeling perfusion imaging, Stephanie B. Stewart, Jonathan M. Koller, Meghan C. Campbell, Joel S. Perlmutter, and Kevin J. Black
Cooperation between Noncanonical Ras Network Mutations, Edward C. Stites, Paul C. Trampont, Lisa B. Haney, Scott F. Walk, and Kodi S. Ravichandran
Inherited CHST11/MIR3922 deletion is associated with a novel recessive syndrome presenting with skeletal malformation and malignant lymphoproliferative disease, Nathan Stitziel and et al
A case of non-cirrhotic portal hypertension associated with chronic didanosine therapy, Matthew Stotts, Phillip Chisholm, Diana Nurutdinova, and Haripriya Maddur
Enhancing workplace wellness efforts to reduce obesity: A qualitative study of low-wage workers in St Louis, Missouri, 2013-2014, Jaime Strickland, Amy A. Eyler, Jason Q. Purnell, Anna M. Kinghorn, Cynthia Herrick, and Bradley A. Evanoff
Worksite influences on obesogenic behaviors in low-wage workers in St Louis, Missouri, 2013-2014, Jaime R. Strickland, Galen Pizzorno, Anna M. Kinghorn, and Bradley A. Evanoff
The metabolomics of asthma control: A promising link between genetics and disease, Robert C. Strunk and et al
Does Bacillus anthracis lethal toxin directly depress myocardial function? A review of clinical cases and preclinical studies, Dante A. Suffredini, Hanish Sampath-Kumar, Yan Li, Lernik Ohanjanian, Kenneth E. Remy, Xizhong Cui, and Peter Q. Eichacker
Targeted treatments for multiple myeloma: Specific role of carfilzomib, Dhivya Sugumar, Jesse Keller, and Ravi Vij
Structural dynamics of E. coli single-stranded DNA binding protein reveal DNA wrapping and unwrapping pathways, Sukrit Suksombat, Rustem Khafizov, Alexander G. Kozlov, Timothy M. Lohman, and Yann R. Chemla
Transcription errors induce proteotoxic stress and shorten cellular lifespan, Daniel W. Summers and et al
Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease, Guruswami S.M. Sundaram, Dhruva Dhavale, Julie L. Prior, Jothilingam Sivapackiam, Richard Laforest, Paul Kotzbauer, and Vijay Sharma
Role of visual and non-visual cues in constructing a rotation-invariant representation of heading in parietal cortex, Adhira Sunkara, Gregory C. DeAngelis, and Dora E. Angelaki
A single brain-derived neurotrophic factor infusion into the dorsomedial prefrontal cortex attenuates cocaine self-administration-induced phosphorylation of synapsin in the nucleus accumbens during early withdrawal, Wei-Lun Sun, Sarah A. Eisenstein, Agnieszka Zelek-Molik, and Jacqueline F. McGinty
Pain treatment and antiretroviral medication adherence among vulnerable HIV-positive patients, Hilary L. Surratt, Steven P. Kurtz, Maria A. Levi-Minzi, Theodore J. Cicero, Kiyomi Tsuyuki, and Catherine L. O'Grady
Quantitative amyloid imaging using image-derived arterial input function, Yi Su, Tyler M. Blazey, Abraham Z. Snyder, Marcus E. Raichle, Russ C. Hornbeck, Patricia Aldea, John C. Morris, and Tammie L. S. Benzinger
Securely measuring the overlap between private datasets with cryptosets, S. Joshua Swamidass, Matthew Matlock, and Leon Rozenblit
Workplace social and organizational environments and healthy-weight behaviors, Rachel G. Tabak, J. Aaron Hipp, Christine M. Marx, and Ross C. Brownson
Dissemination of health-related research among scientists in three countries: Access to resources and current practices, Rachel G. Tabak, Rodrigo S. Reis, Paul Wilson, and Ross C. Brownson
Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription, Shugaku Takeda, Satoru Sasagawa, Toshinao Oyama, Adam C. Searleman, Todd D. Westergard, Emily H. Cheng, and James J. Hsieh
Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model, Miwa Tanaka, Shuichi Yamaguchi, Yukari Yamazaki, Hideyuki Kinoshita, Koichiro Kuwahara, Kazuwa Nakao, Patrick Y. Jay, Tetsuo Noda, and Takuro Nakamura
Characterization of herpes simplex virus 2 primary microRNA transcript regulation, Shuang Tang, Marta Bosch-Marce, Amita Patel, Todd P. Margolis, and Philip R. Krause
Role of RNase H1 in DNA repair: Removal of single ribonucleotide misincorporated into DNA in collaboration with RNase H2, Elias Tannous, Eiko Kanaya, and Shigenori Kanaya
Transcriptomic-wide discovery of direct and indirect HuR RNA targets in activated CD4+ T cells, Patsharaporn Techasintana, J. Wade Davis, Matthew M. Gubin, Joseph D. Magee, and Ulus Atasoy
Ketamine infusion for patients receiving extracorporeal membrane oxygenation support: A case series, Bethany Tellor, Nicole Shin, Thomas J. Graetz, and Michael S. Avidan
Inadequate source control and inappropriate antibiotics are key determinants of mortality in patients with intra-abdominal sepsis and associated bacteremia, Bethany Tellor, Lee P. Skrupky, William Symons, Eric High, Scott T. Micek, and John E. Mazuski
DNA2 drives processing and restart of reversed replication forks in human cells, Saravanabhavan Thangavel, Matteo Berti, Maryna Levikova, Cosimo Pinto, Shivasankari Gomathinayagam, Marko Vujanovic, Ralph Zellweger, Hayley Moore, Eu Han Lee, Eric A. Hendrickson, Petr Cejka, Sheila Stewart, Massimo Lopes, and Alessandro Vindigni
Excessive daytime sleepiness is associated with changes in salivary inflammatory genes transcripts, Matthew S. Thimgan, Cristina Toedebusch, Jennifer McLeland, Stephen P. Duntley, and Paul J. Shaw
Temporal trends in the systemic inflammatory response syndrome, sepsis, and medical coding of sepsis, Benjamin S. Thomas, S. Reza Jafarzadeh, David K. Warren, Sandra McCormick, Victoria J. Fraser, and Jonas Marschall
Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells, Dinesh Thotala, Rowan M. Karvas, John A. Engelbach, Joel R. Garbow, Andrew N. Hallahan, Todd A. Dewees, Andrei Laszlo, and Dennis E. Hallahan
Genetically identified suppressed-by-contrast retinal ganglion cells reliably signal self-generated visual stimuli, Nai-Wen Tien, James T. Pearson, Charles R. Heller, Jay Demas, and Daniel Kerschensteiner
Longitudinal associations between physical and cognitive performance among community-dwelling older adults, Magdalena I. Tolea, John C. Morris, and James E. Galvin
Case report: A case of diabetic ketoacidosis following chikungunya virus infection, Illya Tolokh, Timothy Laux, and Daniel Kim
Induction and processing of the radiation-induced gamma-H2AX signal and Its link to the underlying pattern of DSB: A combined experimental and modelling study, Francesco Tommasino, Thomas Friedrich, Burkhard Jakob, Barbara Meyer, Marco Durante, and Michael Scholz
Selective deletion of cochlear hair cells causes rapid age-dependent changes in spiral ganglion and cochlear nucleus neurons, Ling Tong, Melissa K. Strong, Tejbeer Kaur, Jose M. Juiz, Elizabeth C. Oesterle, Clifford Hume, Mark E. Warchol, Richard D. Palmiter, and Edwin W. Rubel
Pooled sequencing of candidate genes implicates rare variants in the development of asthma following severe RSV bronchiolitis in infancy, Dara G. Torgerson, Tusar Giri, Todd E. Druley, Jie Zheng, Scott Huntsman, Max A. Seibold, Andrew L. Young, Toni Schweiger, Huiqing Yin-Declue, Geneline D. Sajol, Kenneth B. Schechtman, Ryan D. Hernandez, Adrienne G. Randolph, Leonard B. Bacharier, and Mario Castro
Coronary computed tomography angiography of spontaneous coronary artery dissection: A case report and review of the literature, Stephanie C. Torres-Ayala, Jose Maldonado, J. Scott Bolton, and Sanjeev Bhalla
Pain and poppies: The good, the bad, and the ugly of Opioid analgesics, Tuan Trang, Ream Al-Hasani, Daniela Salvemini, Michael W. Salter, Howard Gutstein, and Catherine M. Cahill
Development and validation of the 34-Item disability screening questionnaire (DSQ-34) for use in low and middle income countries epidemiological and development surveys, Jean-Fracois Trani, Ganesh Muneshwar Babulal, and Parul Bakhshi
Mental illness, poverty and stigma in India: A case–control study, Jean-Francois Trani, Parul Bakhshi, Jill Kuhlberg, Sreelatha S. Narayanan, Hemalatha Venkataraman, Nagendra N. Mishra, Nora E. Groce, Sushrut Jadhav, and Smita Deshpande
PCSK9 variation and association with blood pressure in African Americans: Preliminary findings from the HyperGEN and REGARDS studies, Ngan T. Tran, Stella Aslibekyan, Hemant K. Tiwari, Degui Zhi, Yun Ju Sung, Steven C. Hunt, D. C. Rao, Ulrich Broeckel, Suzanne E. Judd, Paul Muntner, Shia T. Kent, Donna K. Arnett, and Marguerite R. Irvin
MicroRNA-223 regulates granulopoiesis but is not required for HSC maintenance in mice, Maria C. Trissal, Ricardo A. DeMoya, Amy P. Schmidt, and Daniel C. Link
Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment, Shaw-Wei David Tsen, Nisha Donthi, Victor La, Wen-Han Hsieh, Yen-Der Li, Jayne Knoff, Alexander Chen, Tzyy-Choou Wu, Chien-Fu Hung, Samuel Achilefu, and Kong-Thon Tsen
A multi-center, randomized, controlled, pivotal study to assess the safety and efficacy of a Selective Cytopheretic Device in patients with acute kidney injury, James A. Tumlin, Claude M. Galphin, Ashita J. Tolwani, Micah R. Chan, Anitha Vijayan, Kevin Finkel, Balazs Szamosfalvi, Devasmita Dev, J. Ricardo DaSilva, Brad C. Astor, Alexander S. Yevzlin, H. David Humes, and SCD Investigator Group
