The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2015
Influence of home and school environments on specific dietary behaviors among postpartum, high-risk teens, 27 states, 2007-2009, Megan A. Clarke, Debra L. Haire-Joshu, Cynthia D. Schwarz, Rachel G. Tabak, and Corinne E. Joshu
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders, Paul Cliften, Jeffrey Milbrandt, and et al
Human gephyrin is encompassed within giant functional noncoding yin–yang sequences, Sharlee Climer, Alan R. Templeton, and Weixiong Zhang
Sickle cell disease: Wheeze or asthma?, Robyn T. Cohen, Elizabeth S. Klings, and Robert C. Strunk
A twin study of breastfeeding with a preliminary genome-wide association scan, Lucia Colodro-Conde, Gu Zhu, Robert A. Power, Anjali Henders, Andrew C. Heath, Pamela A F Madden, Grant W. Montgomery, Sarah Medland, Juan R. Ordoñana, and Nicholas G. Martin
Association between dietary patterns during pregnancy and birth size measures in a diverse population in Southern US, Uriyoán Colón-Ramos, Susan B. Racette, Jody Ganiban, Thuy G. Nguyen, Mehmet Kocak, Kecia N. Carroll, Eszter Völgyi, and Frances A. Tylavsky
Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel, Paige E. Cooper, Monica Sala-Rabanal, Sun Joo Lee, and Colin G. Nichols
Stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology, N. S. Corral-Frías, Y. S. Nikolova, L. J. Michalski, D. A. A. Baranger, A. R. Hariri, and R. Bogdan
The readability of online breast cancer risk assessment tools, Sarah Cortez, Melissa Milbrandt, Kimberly A. Kaphingst, Aimee S. James, and Graham A. Colditz
In vivo kinetic approach reveals slow SOD1 turnover in the CNS, Matthew J. Crisp, Kwasi G. Mawuenyega, Bruce W. Patterson, Naveen C. Reddy, Robert Chott, Wade K. Self, Conrad C. Weihl, Jennifer Jockel-Balsarotti, Arun S. Varadhachary, Robert C. Bucelli, Kevin E. Yarasheski, Randall J. Bateman, and Rimothy M. Miller
Expression quantitative trait loci information improves predictive modeling of disease relevance of non-coding genetic variation, Damien C. Croteau-Cronka, Angela J. Rogers, Towfique Raj, Michael J. McGeachie, Weiliang Qui, John P. Ziniti, Benjamin J. Stubbs, Liming Liang, Fernando D. Martinez, Robert C. Strunk, Robert F. Lemanske Jr., Andrew H. Liu, Barbara E. Stranger, Vincent J. Carey, and Benjamin A. Raby
Epidemiology, co-infections, and outcomes of viral pneumonia in adults an observational cohort study, Matthew P. Crotty, Shelby Meyers, Nicholas B. Hampton, Stephanie Bledsoe, David J. Ritchie, Richard S. Buller, Gregory A. Storch, Scott T. Micek, and Marin H. Kollef
Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: An opportunity for stewardship, Matthew P. Crotty, Shelby Meyers, Nicholas Hampton, Stephanie Bledsoe, David J. Ritchie, Richard S. Buller, Gregory A. Storch, Marin H. Kollef, and Scott T. Micek
Automatic analysis (aa): Efficient neuroimaging workflows and parallel processing using Matlab and XML, Rhodri Cusack, Alejandro Vicente-Grabovetsky, Daniel J. Mitchell, Conor J. Wild, Tibor Auer, Annika C. Linke, and Jonathan E. Peelle
Butyrate and mucosal inflammation: New scientific evidence supports clinical observation, Kelly Cushing, David M. Alvarado, and Matthew A. Ciorba
Citrulline protects Streptococcus pyogenes from acid stress using the arginine deiminase pathway and the F1Fo-ATPase, Zachary T. Cusumano and Michael G. Caparon
The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma, David Y A Dadey, Vaishali Kapoor, Arpine Khudanyan, Fumihiko Urano, Albert H. Kim, Dinesh Thotala, and Dennis E. Hallahan
Quantitative evaluation of the community research fellows training program, Lucy D'Agostino McGowan, Jewel D. Stafford, Vetta Lynn Thompson, Bethany Johnson-Javois, and Melody S. Goodman
Oxidative stress biomarkers and incidence of postoperative atrial fibrillation in the Omega‐3 Fatty Acids for Prevention of Postoperative Atrial Fibrillation (OPERA) trial, Ralph J. Damiano, Joann Marsala, and et al
The impact of immune system in regulating bone metastasis formation by osteotropic tumors, Lucia D'Amico and Ilaria Roato
The Alternaria genomes database: A comprehensive resource for a fungal genus comprised of saprophytes, plant pathogens, and allergenic species, Ha X. Dang, Barry Pryor, Tobin Peever, and Christopher B. Lawrence
Knocking on closed doors: Host interferons dynamically regulate blood-brain barrier function during viral infections of the central nervous system, Brian P. Daniels and Robyn S. Klein
Trends in opioid analgesic abuse and mortality in the United States, Richard C. Dart, Hilary L. Surratt, Theodore J. Cicero, Mark W. Parrino, S Geoff Severtson, Becki Bucher-Bartelson, and Jody L. Green
General N-and O-linked glycosylation of lipoproteins in mycoplasmas and role of exogenous oligosaccharide, James M. Daubenspeck, David S. Jordan, Warren Simmons, Matthew B. Renfrow, and Kevin Dybvig
A case study of voltage-gated potassium channel antibody-related limbic encephalitis with PET/MRI findings, Brian K. Day, Lawrence Eisenman, Joseph Black, Luigi Maccotta, and R. Edward Hogan
Nonverbal reasoning in preschool children: Investigating the putative risk of secondhand smoke exposure and attention-deficit/hyperactivity disorder as a mediator, Duneesha De Alwis, Mini Tandon, Rebecca Tillman, and Joan Luby
Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers, Joshua T. Dearborn, Steven K. Harmon, Stephen C. Fowler, Karen L. O'Malley, George T. Taylor, Mark S. Sands, and David F. Wozniak
Role of ABCA7 loss-of-function variant in Alzheimer's disease: A replication study in European–Americans, Jorge L. Del-Aguila, Maria Victoria Fernandez, Jessica Jimenez, Kathleen Black, Shengmei Ma, Yuetiva Deming, David Carrell, Ben Saef, Bill Howells, John Budde, and Carlos Cruchaga
Validation of a risk prediction tool for coronary heart disease in middle-aged women, Katerina M. De Vito, Heather J. Baer, Hank Dart, Stephanie E. Chiuve, Eric B. Rimm, and Graham A. Colditz
Preparing for the next epidemic with basic virology, Michael S. Diamond
The amazing brain, Krikor Dikranian
Germline mutations in predisposition genes in pediatric cancer, Li Ding, Elaine R. Mardis, Richard K. Wilson, and et al
Small sized EGFR1 and HER2 specific bifunctional antibody for targeted cancer therapy, Li Ding, Caiping Tian, Song Feng, Guissi Fida, Congying Zhang, Yuxiang Ma, Guanhua Ai, Samuel Achilefu, and Yueqing Gu
Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I, John F. DiPersio and et al
A consensus-based interpretation of the benchmark evidence from South American trials: treatment of intracranial pressure trial, Michael N. Diringer and et al
Filling in the gaps: Anticipatory control of eye movements in chronic mild traumatic brain injury, Mithun Diwakar, Deborah L. Harrington, Jun Maruta, Jamshid Ghajar, Fady El-Gabalawy, Laura Muzzatti, Maurizio Corbetta, Ming-Xiong Huang, and Roland R. Lee
A multi targeting conditionally replicating adenovirus displays enhanced oncolysis while maintaining expression of immunotherapeutic agents, G. Clement Dobbins, Hideyo Ugai, David T. Curiel, and G. Yancey Gillespie
Preparedness of Ob/Gyn residents for fellowship training in gynecologic oncology, David W. Doo, Matthew Powell, Akiva Novetsky, Jeanelle Sheeder, and Saketh R. Guntupalli
Mitochondrial dynamism and heart disease: Changing shape and shaping change, Gerald W. Dorn II
Mitochondrial biogenesis and dynamics in the developing and diseased heart, Gerald W. Dorn II, Rick B. Vega, and Daniel P. Kelly
Mammograms on-the-go—predictors of repeat visits to mobile mammography vans in St Louis, Missouri, USA: A case–control study, Bettina F. Drake, Salmafatima S. Abadin, Sarah Lyons, Su-Hsin Chang, Lauren T. Steward, Susan Kraenzle, and Melody S. Goodman
Toxoplasma actin is required for efficient host cell invasion, Lisa L. Drewry and L. David Sibley
Risk factors for acquisition and loss of Clostridium difficile colonization in hospitalized patients, Erik R. Dubberke, Kimberly A. Reske, Sondra Seiler, Tiffany Hink, Jennie H. Kwon, and Carey-Ann D. Burnham
Response to nodal morphogen gradient is determined by the kinetics of target gene induction, Julien Dubrulle, Benjamin M. Jordan, Laila Akhmetova, Jeffrey A. Farrell, Seok-Hyung Kim, Lilianna Solnica-Krezel, and Alexander F. Schier
Implementing administrative evidence based practices: Lessons from the field in six local health departments across the United States, Kathleen Duggan, Kristelle Aisaka, Rachel G. Tabak, Carson Smith, Paul Erwin, and Ross C. Brownson
Lung cancer treatment outcomes in recipients of lung transplant, Lingling Du, Nathan A. Pennell, Paul Elson, and Nooshin Hashemi-Sadraei
Relationship between abuse and neglect in childhood and diabetes in adulthood: Differential effects by sex, national longitudinal study of adolescent health, Alexis E. Duncan, Wendy F. Auslander, Kathleen K. Bucholz, Darrell L. Hudson, Richard I. Stein, and Neil H. White
CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system, Douglas M. Durrant, Brian P. Daniels, TracyJo Pasieka, Denise Dorsey, and Robyn S. Klein
Comparing interventions and exploring neural mechanisms of exercise in Parkinson disease: A study protocol for a randomized controlled trial, Gammon M. Earhart, Ryan P. Duncan, John L. Huang, Joel S. Perlmutter, and Kristen A. Pickett
CPI motif interaction is necessary for capping protein function in cells, Marc Edwards, Patrick McConnell, Dorothy A. Schafer, and John A. Cooper
Exercise prevents fructose-induced hypertriglyceridemia in healthy young subjects, L Egli, V Lecoulture, F Theytaz, V Campos, L Hodson, P Schneiter, B Mittendorfer, BW Patterson, BA Fielding, PA Gerber, V Giusti, K Berneis, and L Tappy
Kappa Opioid receptor-induced aversion requires p38 MAPK activation in VTA dopamine neurons, Jonathan M. Ehrich, Daniel I. Messinger, Cerise R. Knakal, Jamie R. Kuhar, Selena S. Schatteuer, Michael R. Bruchas, Larry S. Zweifel, Brigitte L. Kieffer, Paul E M Phillips, and Charles Chavkin
Sugarcoated isolation: Evidence that social avoidance is linked to higher basal glucose levels and higher consumption of glucose, Tsachi Ein-Dor, James A. Coan, Abira Reizer, Elizabeth B. Gross, Dana Dahan, Meredyth A. Wegener, Rafael Carel, Claude R. Cloninger, and Ada H. Zohar
Three-year efficacy and safety of a new 52-mg levonorgestrel-releasing intrauterine system, David L. Eisenberg, Courtney A. Schreiber, David K. Turok, Stephanie B. Teal, Carolyn L. Westhoff, Mitchell D. Creinin, and ACCESS IUS Investigators
Emotional eating phenotype is associated with central dopamine D2 receptor binding independent of body mass index, Sarah A. Eisenstein, Allison N. Bischoff, Danuta M. Gradysa, Jo Ann V. Antenor-Dorsey, Jonathan M. Koller, Amal Al-Lozi, Marta Y. Pepino, Samuel Klein, Joel S. Perlmutter, Stephen M. Morelein, Kevin J. Black, and Tamara Hershey
Insulin, central dopamine D2 receptors, and monetary reward discounting in obesity, Sarah A. Eisenstein, Danuta M. Gredysa, Jo Ann Antenor-Dorsey, Leonard Green, Ana Maria Arbelaez, Jonathan M. Koller, Kevin J. Black, Joel S. Perlmutter, Stephen M. Moerlein, and Tamara Hershey
Targeting CD226/DNAX accessory molecule-1 (DNAM-1) in collagen-induced arthritis mouse models, Muriel Elhai, Gilles Chiocchia, Carmen Marchiol, Franck Lager, Gilles Renault, Marco Colonna, Guenter Bernhardt, Yannick Allanore, and Jerome Avouac
Late gastrointestinal tissue effects after hypofractionated radiation therapy of the pancreas, Adnan Elhammali, Mukund Patel, Benjamin Weinberg, Vivek Verma, Jingxia Liu, Jeffrey R. Olsen, and Hiram A. Gay
Diffusion MRI quality control and functional diffusion map results in ACRIN 6677/RTOG 0625: A multicenter, randomized, phase II trial of bevacizumab and chemotherapy in recurrent glioblastoma, Benjamin M. Ellingson, Eunhee Kim, Davis C. Woodworth, Helga Marques, Jerrold L. Boxerman, Yair Safriel, Robert C. McKinstry, Felix Bokstein, Rajan Jain, T. Linda Chi, A. Gregory Sorensen, Mark R. Gilbert, and Daniel P. Barboriak
Intermediate DNA methylation is a conserved signature of genome regulation, GiNell Elliott, Xiaoyun Xing, Xin Zhou, Daofeng Li, Gary D. Stormo, Ting Wang, and et al
Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer, Matthew Ellis and et al
Prospective validation of a 21-gene expression assay in breast cancer, Matthew J. Ellis and et al
Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis, Tim S. Ellison, Samuel J. Atkinson, Veronica Steri, Benjamin M. Kirkup, Michael E J Preedy, Robert T. Johnson, Christina Ruhrberg, Dylan R. Edwards, Jochen G. Schneider, Katherine Weilbaecher, and Stephen D. Robinson
Utilization of an Eilat virus-based chimera for serological detection of chikungunya infection, Jesse H. Erasmus, James Needham, Syamal Raychaudhuri, Michael S. Diamond, David W. C. Beasley, Stan Morkowski, Henrik Salje, Ildefonso Fernandez Salas, Dal Young Kim, Ilya Frolov, Farooq Nasar, and Scott C. Weaver
Assessment of training and technical assistance needs of Colorectal Cancer Control Program Grantees in the U.S., Cam Escoffery, Peggy Hannon, Annette E. Maxwell, Thuy Vu, Jennifer Leeman, Andrea Dwyer, Caitlin Mason, Shaina Sowles, Ketra Rice, and Lindsay Gressard
Hepatic steatosis as a marker of metabolic dysfunction, Elisa Fabbrini and Faidon Magkos
Metabolically normal obese people are protected from adverse effects following weight gain, Elisa Fabbrini, Jun Yoshino, Mihoko Yoshino, Faidon Magkos, Courtney T. Luecking, Dmitri Samovski, Gemma Fraterrigo, Adewole L. Okunade, Bruce W. Patterson, and Samuel Klein
Importance of decision support implementation in emergency department vancomycin dosing, Brett Faine, Nicholas Mohr, Kari K. Harland, Kathryn Rolfes, Blake Porter, and Brian M. Fuller
An ensemble approach to accurately detect somatic mutations using SomaticSeq, Li Tai Fang, Pegah Tootoonchi Afshar, Aparna Chhibber, Marghoob Mohiyuddin, Yu Fan, John C. Mu, Greg Gibeling, Sharon Barr, Narges Bani Asadi, Mark B. Gerstein, Daniel C. Koboldt, Wenyi Wang, Wing H. Wong, and Hugo YK Lam
Enterovirus D68-associated acute respiratory distress syndrome in adult, United States, 2014, John J. Farrell, Ossama Ikladios, Kristine M. Wylie, Lindsay M. O'Rourke, Kristin S. Lowery, Jenna S. Cromwell, Todd N. Wylie, Elsa L. Vazquez Melendez, Yves Makhoul, Rangarajan Sampath, Robert A. Bonomo, and Gregory A. Storch
Differential impact of LPG-and PG-deficient Leishmania major mutants on the immune response of human dendritic cells, Michelle A. Favila, Nicholas S. Geraci, Asha Jayakumar, Suzanne Hickerson, Janet Mostrom, Salvatore J. Turco, Stephen M. Beverley, and Mary Ann McDowell
How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila, R. Faville, B. Kottler, G. J. Goodhill, P. J. Shaw, and B. van Swinderen
Pathological complete response in breast cancer patients following neoadjuvant chemotherapy at a Comprehensive Cancer Center: The natural history of an elusive prognosticator, Oluwadamilola M. Fayanju, Iheoma Nwaogu, Donna B. Jeffe, and Julie A. Margenthaler
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels, Mary F. Feitosa, Kai Ye, Ingrid B. Borecki, and et al
Distance-dependent plasmon-enhanced fluorescence of upconversion nanoparticles using polyelectrolyte multilayers as tunable spacers, Ai Ling Feng, Min Li You, Limei Tian, Srikanth Singamaneni, Ming Liu, Zhenfeng Duan, Tian Jian Lu, Feng Xu, and Min Lin
Does diacylglycerol accumulation in fatty liver disease cause hepatic insulin resistance?, Brian N. Finck and Angela M. Hall
Digynic triploidy: Utility and challenges of noninvasive prenatal testing, Julie Fleischer, Archana Shenoy, Katherine Goetzinger, Catherine E. Cottrell, Dustin Baldridge, Frances V. White, and Marwan Shinawi
Association of knowledge, preventive counseling and personal health behaviors on physical activity and consumption of fruits or vegetables in community health workers, Alex A. Florindo, Ross C. Brownson, Gregore I. Mielke, Grace AO Gomes, Diana C. Parra, Fernando V. Siqueira, Felipe Lobelo, Eduardo J. Simoes, Luiz R. Ramos, Mario M. Bracco, and Pedro C. Hallal
Standardization and normative data of the Greek version of the temperament and character inventory (TCI), Konstantinos N. Fountoulakis, Sandor Rozsa, Melina Siamouli, Katerina Moutou, Eleonora Pantoula, and Claude Robert Cloninger
Leveraging existing data sets to generate new insights into Alzheimer’s disease biology in specific patient subsets, Kevin D. Fowler, Jason M. Funt, Maxim N. Artyomov, Benjamin Zeskind, and Sarah E. Kolitz
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners, Stephanie I. Fraley, Yunfeng Feng, Anjil Giri, Gregory D. Longmore, and Denis Wirtz
Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions, Stephanie I. Fraley, Pei-hsun Wu, Lijuan He, Yunfeng Feng, Ranjini Krisnamurthy, Gregory D. Longmore, and Denis Wirtz
Quantitative autism symptom patterns recapitulate differential mechanisms of genetic transmission in single and multiple incidence families, Thomas Frazier, Eric A. Youngstrom, Antonio Y. Hardan, Stelios Georgiades, John N. Constantino, and Charis Eng
Differing effects when using phenylephrine and norepinephrine to augment cerebral blood flow after traumatic brain injury in the immature brain, Stuart H. Friess, Benjamin Bruins, Todd J. Kilbaugh, Colin Smith, and Susan S. Margulies
Decompressive craniectomy reduces white matter injury after controlled cortical impact in mice, Stuart H. Friess, Jodi B. Lapidus, and David L. Brody
Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications, Anja Fuchs, Timothy J. Wilson, Marco Colonna, and et al
TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits, Robert S. Fulton, David E. Larson, Tracie L. Deluca, Michelle O'Laughlin, Catrina C. Fronick, Lucinda L. Fulton, Elaine R. Mardis, and et al
Development of a multiparametric voxel-based magnetic resonance imaging biomarker for early cancer therapeutic response assessment, Craig J. Galban, Benjamin Lemasson, Benjamin A. Hoff, Timothy D. Johnson, Pia C. Sundgren, Christina Tsien, Thomas L. Chenevert, and Brian D. Ross
Predicting clinical binary outcome using multivariate longitudinal data: Application to patients with newly diagnosed primary open-angle glaucoma, Feng Gao, J. Philip Miller, Julia A. Beiser, Chengjie Xiong, and Mae O. Gordon
Two potential hookworm DAF-16 target genes, SNR-3 and LPP-1: gene structure, expression profile, and implications of a cis-regulatory element in the regulation of gene expression, Xin Gao, Kevin Goggin, Jason Qian, and John M. Hawdon
Dual-modality photoacoustic and ultrasound imaging system for noninvasive sentinel lymph node detection in patients with breast cancer, Alejandro Garcia-Uribe, Todd N. Erpelding, Arie Krumholz, Haixin Ke, Konstantin Maslov, Catherine Appelton, Julie A. Margenthaler, and Lihong V. Wang
Levamisole/cocaine induced systemic vasculitis and immune complex glomerulonephritis, Lohit Garg, Sagar Gupta, Abhishek Swami, and Ping Zhang
Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast, Zoran Gatalica, Semir Vranic, Anatole Ghazalpour, Joanne Xiu, Idris Tolgay Ocal, John McGill, Ryan P. Bender, and Erin Discianno
Systemic EP4 inhibition increases adhesion formation in a murine model of flexor tendon repair, Michael B. Geary, Caitlin A. Orner, Fatima Bawany, Hani A. Awad, Warren C. Hammert, Regis J. O'Keefe, and Alayna E. Loiselle
Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal carcinoma cells, Susan J. Gelman, Nathaniel G. Mahieu, Kevin Cho, Elizabeth M. Llufrio, Timothy A. Wencewicz, and Gary J. Patti
Testicular leydig cell tumor with metachronous lesions: Outcomes after metastasis resection and cryoablation, Julio J. Geminiani, Stephen D. Marshall, Tammy S. Ho, and Steven B. Brandes
The N-Terminal domain of SIRT1 is a positive regulator of endogenous SIRT1-dependent deacetylation and transcriptional outputs, Fiorella Ghisays, Cynthia S. Brace, Shawn M. Yackly, Hyock Joo Kwon, Kathryn F. Mills, Elena Kashentseva, Igor P. Dmitriev, David T. Curiel, Shin-ichiro Imai, and Tom Ellenberger
Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects, Paul Giacomin, Martha Zakrzewski, John Croese, Xiaopei Su, Javier Sotillo, Leisa McCann, Severine Navarro, Makedonka Mitreva, Lutz Krause, Alex Loukas, and Cinzia Cantacessi
Extending injury- and disease-resistant CNS phenotypes by repetitive epigenetic conditioning, Jeffrey M. Gidday
