The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2012

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The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses, Efrem S. Lim, Lily I. Wu, Harmit S. Malik, and Michael Emerman

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Political and social determinants of life expectancy in less developed countries: A longitudinal study, Ro-Ting Lin, Ya-Mei Chen, Lung-Chang Chien, and Chang-Chuan Chan

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DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease, Xiangmin Lin, Travis J. Cook, Cyrus P. Zabetian, James B. Leverenz, Elaine R. Peskind, Shu-Ching Hu, Kevin C. Cain, Catherine Pan, John Scott Edgar, David R. Goodlett, Brad A. Racette, Harvey Checkoway, Thomas J. Montine, Min Shi, and Jing Zhang

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Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success, Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, and Alexander S. Krupnick

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Compound heterozygous mutations in the SUR1 (ABCC 8) subunit of pancreatic KATP channels cause neonatal diabetes by perturbing the coupling between Kir6.2 and SUR1 subunits, Yu-Wen Lin, Alejandro Akrouh, YeouChing Hsu, Nkecha Hughes, Colin G. Nichols, and Diva D. De Leon

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Correlations of coronary plaque wall thickness with wall pressure and wall pressure gradient: A representative case study, Biyue Liu, Jie Zheng, Richard Bach, and Dalin Tang

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CHFR is important for the first wave of ubiquitination at DNA damage sites, Chao Liu, Jiaxue Wu, Sharad C. Paudyal, Zhongsheng You, and Xiaochun Yu

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Intravital 2-photon imaging of leukocyte trafficking in beating heart, Wenjun Li, Ruben G. Nava, Alejandro C. Bribriesco, Bernd H. Zinselmeyer, Jessica H. Spahn, Andrew E. Gelman, Alexander S. Krupnick, Mark J. Miller, and Daniel Kreisel

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The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel, Lipin Loo, Andrew J. Shepherd, Aaron D. Mickle, Ramon A. Lorca, Leonid P. Shutov, Yuriy M. Usachev, and Durga P. Mohapatra

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Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbionts, Catherine Lozupone, Karoline Faust, Jeroen Raes, Jeremiah J. Faith, Daniel N. Frank, Jesse Zaneveld, Jeffrey I. Gordon, and Rob Knight

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The association of neonatal dacryocystoceles and infantile dacryocystitis with nasolacrimal duct cysts (an American Ophthalmogical Society Thesis), Gregg T. Lueder

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An Australian twin study of cannabis and other illicit drug use and misuse, and other psychopathology, Michael T. Lynskey, Arpana Agrawal, Anjali Henders, Elliot C. Nelson, Pamela A.F. Madden, and Nicholas G. Martin

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Re-orientation of clinical research in traumatic brain injury: Report of an international workshop on comparative effectiveness research, Andrew I.R. Maas, David K. Menon, Hester F. Lingsma, Jose A. Pineda, M. Elizabeth Sandel, and Geoffery T. Manley

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Splint: The efficacy of orthotic management in rest to prevent equinus in children with cerebral palsy, a randomised controlled trial, Josina C. Maas, Annet J. Dallmeijer, Peter A. Huijing, Janice E. Brunstrom-Hernandez, Petra J. van Kampen, Richard T. Jaspers, and Jules G. Becher

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Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models, Cynthia X. Ma, Shirong Cai, Shunqiang Li, Christine E. Ryan, Zhangfang Guo, W. Timothy Schaiff, Li Lin, Jeremy Hoog, Reece J. Goiffon, Aleix Prat, Rebecca L. Aft, Matthew J. Ellis, and Helen Piwnica-Worms

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Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion, P. A. F. Madden, A. C. Heath, and et al

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Diazoxide maintains human myocyte volume homeostasis during stress, Sara K. Maffit, Angela D. Sellitto, Ashraf S. Al-Dadah, Richard B. Schuessler, Ralph J. Damiano Jr., and Jennifer S. Lawton

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Putative factors that may modulate the effect of exercise on liver fat: Insights from animal studies, Faidon Magkos

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A four-subunit DNA polymerase ζ complex containing Pol δ accessory subunits is essential for PCNA-mediated mutagenesis, Alena V. Makarova, Joseph L. Stodola, and Peter M. Burgers

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Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages, Nicole S. Maloney, Larissa B. Thackray, Gautam Goel, Seungmin Hwang, Erning Duan, Punit Vachharajani, Ramnik Xavier, and Herbert W. Virgin

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Hippocampal shape and volume changes with antipsychotics in early stage psychotic illness, Daniel Mamah, Michael P. Harms, Deanna Barch, Martin Styner, Jeffrey A. Lieberman, and Lei Wang

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Warfarin and aspirin in patients with heart failure and sinus rhythm, Douglas L. Mann and et al

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Short report: Genetic characterization of atypical Mansonella (Mansonella) ozzardi microfilariae in human blood samples from Northeastern Peru, Luis A. Marcos, Nancy Arrospide, Sergio Recuenco, Cesar Cabezas, Gary J. Weil, and Peter U. Fischer

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Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data, Elaine R. Mardis, Richard K. Wilson, and et al

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The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K+ channels, Céline Marionneau, Yarimar Carrasquillo, Aaron J. Norris, R. Reid Townsend, Lori L. Isom, Andrew J. Link, and Jeanne M. Nerbonne

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Mapping a complete neural population in the retina, Olivier Marre, Dario Amodei, Nikhil Deshmukh, Kolia Sadeghi, Frederick Soo, Timothy E. Holy, and Michael J. Berry

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Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data, John Martin, Sahar Abubucker, Esley Heizer, Christina M. Taylor, and Makedonka Mitreva

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Optimizing read mapping to reference genomes to determine composition and species prevalence in microbial communities, John Martin, Sean Sykes, Sarah Young, Karthik Kota, Ravi Sanka, Nihar Sheth, Joshua Orvis, Erica Sodergren, Zhengyuan Wang, George M. Weinstock, and Makedonka Mitreva

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Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death, Xiucui Ma, Rebecca J. Godar, Haiyan Liu, and Abhinav Diwan

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Autophagy is impaired in cardiac ischemia-reperfusion injury, Xiucui Ma, Haiyan Liu, Sarah R. Foyil, Rebecca J. Godar, Carla J. Weinheimer, and Abhinav Diwan

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Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus, Zhongmin Alex Ma, Zhengshan Zhao, and John Turk

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Recognizing and managing the expanded risk of tumor lysis syndrome in hematologic and solid malignancies, Ali McBride and Peter Westervelt

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Structural mechanism of ER retrieval of MHC class I by cowpox, William H. McCoy IV, Xiaoli Wang, Wayne M. Yokoyama, Ted H. Hansen, and Daved H. Fremont

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Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing, Emily C. McCusker, Claire Bagnéris, Claire E. Naylor, Ambrose R. Cole, Nazzareno D'Avanzo, Colin G. Nichols, and B A. Wallace

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Environmental influences predominate in remission from alcohol use disorder in young adult twins, V. V. McCutcheon, J. D. Grant, A. C. Heath, K. K. Bucholz, C. E. Sartor, E. C. Nelson, P. A F Madden, and N. G. Martin

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Automated web-based request mechanism for workflow enhancement in an academic customer-focused biorepository, Sandra A. McDonald, Benjamin J. Ryan, Amy Brink, and Victoria L. Holtschlag

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Fee-for-service as a business model of growing importance: the academic biobank experience, Sandra A. McDonald, Kara Sommerkamp, Maureen Egan-Palmer, Karen Kharasch, and Victoria Holtschlag

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Vascular anatomy of the tibiofibular syndesmosis, Kathleen E. McKeon, Rick W. Wright, Jeffrey E. Johnson, Jeremy J. McCormick, and Sandra E. Klein

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Lack of short-term effectiveness of rotating treadmill training on turning in people with mild-to-moderate Parkinson's disease and healthy older adults: A randomized, controlled study, Marie E. McNeely and Gammon M. Earhart

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Transcriptomic and proteomic analyses of a Wolbachia- free filarial parasite provide evidence of trans-kingdom horizontal gene transfer, Samantha N. McNulty, Sahar Abubucker, Gabriel M. Simon, Makedonka Mitreva, Nathan P. McNulty, Kerstin Fischer, Kurt C. Curtis, Norbert W. Brattig, Gary J. Weil, and Peter U. Fischer

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Comparing the mitochondrial genomes of Wolbachia-dependent and independent filarial nematode species, Samantha N. McNulty, Andrew S. Mullin, Jefferson A. Vaughan, Vasyl V. Tkach, Gary J. Weil, and Peter U. Fischer

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What would make getting colorectal cancer screening easier? Perspectives from screeners and nonscreeners, Gilda G. Medina, Amy McQueen, Anthony J. Greisinger, L. Kay Bartholomew, and Sally W. Vernon

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When planning results in loss of control: Intention-based reflexivity and working-memory, Nachshon Meiran, Michael W. Cole, and Todd S. Braver

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Progression from sustained BK viruria to sustained BK viremia with immunosuppression reduction is not associated with changes in the noncoding control region of the BK virus genome, Imran A. Memon, Bijal A. Parikh, Monique Gaudreault-Keener, Rebecca Skelton, Gregory A. Storch, and Daniel C. Brennan

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An analysis of the transcriptome of Teladorsagia circumcincta: Its biological and biotechnological implications, Ranjeeta Menon, Robin B. Gasser, Makedonka Mitreva, and Shoba Ranganathan

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An institutional perspective on the impact of recent antibiotic exposure on length of stay and hospital costs for patients with gram-negative sepsis, Scott Micek, Michael T. Johnson, Richard Reichley, and Marin H. Kollef

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Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint, Alexander P. Miceli, Anthony J. Saporita, and Jason D. Weber

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The business case for a diabetes self-management intervention in a community general hospital, Ashley Micklethwaite, Carol A. Brownson, Mary L. O'Toole, and Kerry E. Kilpatrick

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Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein, Rita PS Middelberg, Andrew C. Heath, Pamela AF Madden, Grant W. Montgomery, Nicholas G. Martin, and John B. Whitfield

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Deciphering a global network of functionally associated post-translational modifications, Pablo Minguez, Luca Parca, Francesca Diella, Daniel R. Mende, Runjun Kumar, Manuela Helmer-Citterich, Anne-Claude Gavin, Vera van Noort, and Peer Bork

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Quantitative trait loci affecting liver fat content in mice, Olga Minkina, James M. Cheverud, Gloria Fawcett, Clay F. Semenkovich, and Jane P. Kenney-Hunt

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Development of a new humanized mouse model to study acute inflammatory arthritis, Alexander V. Misharin, G K. Haines, Shawn Rose, Angelical K. Gierut, Richard S. Hotchkiss, and Harris Perlman

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Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration, Albert L. Misko, Yo Sasaki, Elizabeth Tuck, Jeffrey Milbrandt, and Robert H. Baloh

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Association between human papillomavirus DNA and temporal arteritis, Amir Mohammadi, John D. Pfeifer, and James S. Lewis

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Intestinal adenocarcinoma arising in urinary conduits, Genevieve C. Moyer, Robert L. Grubb III, and Frank E. Johnson

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Ligand-induced movements of inner transmembrane helices of Glut1 revealed by chemical cross-linking of di-cysteine mutants, Mike Mueckler and Carol Makepeace

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Neural synchrony during response production and inhibition, Viktor Muller and Andrey P. Anokhin

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Plasmodium falciparum  heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers, Vasant Muralidharan, Anna Oksman, Priya Pal, Susan Lindquist, and Daniel E. Goldberg

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Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study, Mariana Murea, Thomas C. Register, Jasmin Divers, Donald W. Bowden, J. Jeffrey Carr, Caresse R. Hightower, Jianzhao Xu, S. Carrie Smith, Keith A. Hruska, Carl D. Langefeld, and Barry I. Freedman

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Frequent hospital readmissions for Clostridium difficile infection and the impact on estimates of hospital-associated C. difficile burden, Courtney R. Murphy, Taliser R. Avery, Erik R. Dubberke, and Susan S. Huang

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Periacetabular osteotomy and combined femoral head-neck junction osteochondroplasty: A minimum two-year follow-up cohort study, Nader A. Nassif, Perry L. Schoenecker, Robert Thorsness, and John C. Clohisy

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Meniscal Repair outcomes at greater than five years: A systematic literature review and meta-analysis, Jeffrey J. Nepple, Warren R. Dunn, and Rick W. Wright

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Description of a multicenter safety checklist for intraoperative hemorrhage control while clamped during robotic partial nephrectomy, Kenneth G. Nepple, Gurdarshan S. Sandhu, Craig G. Rogers, Mohamad E. Allaf, Jihad H. Kaouk, Robert S. Figenshau, Michael D. Stifelman, and Sam B. Bhayani

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Reliability and validity of the Wolfram Unified Rating Scale (WURS), Chau Nguyen, Erin R. Foster, Alexander R. Paciorkowski, Amy Viehoever, Colleen Considine, Aidena Bondurant, Bess A. Marshall, Tamara Hershey, and Washington University Wolfram Study Group

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Hospitalized cardiovascular events in patients with diabetic macular edema, Bao-Anh Nguyen-Khoa, Earl L. Goehring Jr., Winifred Werther, Anne E. Fung, Diana V. Do, Rajendra S. Apte, and Judith K. Jones

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State legislation savvy: A primer and tools for online legislative research in the United States, Leah M. Nguyen, Amy A. Eyler, Jooyoung Kong, and Ross C. Brownson

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Spark: A navigational paradigm for genomic data exploration, Cydney B. Nielsen, Hamid Younesy, Henriette O'Geen, Xiaoqin Xu, Andrew R. Jackson, Aleksandar Milosavljevic, Ting Wang, Joseph F. Costello, Martin Hirst, Peggy J. Farnham, and Steven J.M. Jones

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The metal ion-dependent adhesion site motif of the Enterococcus faecalis EbpA pilin mediates pilus function in catheter-associated urinary tract infection, Hailyn V. Nielsen, Pascale S. Guiton, Kimberly A. Kline, Gary C. Port, Jerome S. Pinkner, Fabrice Neiers, Staffan Normark, Birgitta Henriques-Normark, Michael G. Caparon, and Scott J. Hultgren

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A window into domain amplification through Piccolo in teleost fish, Michael L. Nonet

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MHC class I cross-presentation by dendritic cells counteracts viral immune evasion, Katrin Nopora, Caroline A. Bernhard, Christine Ried, Alejandro A. Castello, Kenneth M. Murphy, Peggy Marconi, Ulrich Koszinowski, and Thomas Brocker

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A bioinformatics filtering strategy for identifying radiation response biomarker candidates, Jung Hun Oh, Harry P. Wong, Xiaowei Wang, and Joseph O. Deasy

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Strategies proposed by healthy kids, healthy communities partnerships to prevent childhood obesity, Punam Ohri-Vachaspati, Laura Leviton, Philip Bors, Laura K. Brennan, Ross C. Brownson, and Sarah Strunk

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Incorporating patient preference into the management of infertility in women with polycystic ovary syndrome, Ugochi C. Okoroafor and Emily S. Jungheim

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Quantitative brain electrical activity in the initial screening of mild traumatic brain injuries, Brian O'Neil, Leslie S. Prichep, Roseanne Naunhemi, and Robert Chabot

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Cancer immunoediting by the innate immune system in the absence of adaptive immunity, Timothy O'Sullivan, Robert Saddawi-Konefka, William Vermi, Catherine M. Koebel, Cora Arthur, J. Michael White, Ravi Uppaluri, Daniel M. Andrews, Shin Foong Ngiow, Michele W. L. Teng, Mark J. Smith, Robert D. Schreiber, and Jack D. Bui

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Constitutively active canonical NF-kB pathway induces severe bone loss in mice, Jesse E. Otero, Tim Chen, Kaihua Zhang, and Yousef Abu-Amer

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Cystatin C and baseline renal function among HIV-infected persons in the SUN study, Edgar Turner Overton, Pragna Patel, Kristin Mondy, Tim Bush, Lois Conley, Frank Rhame, Erna Milunka Kojic, John Hammer, Keith Henry, and John T. Brooks

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Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection, Carly Page, Lindsay Golcohea, Krystal Matthews, Yong Zhang, Peter Klover, Michael J. Holtzman, Lothar Hennighausen, and Matthew Frieman

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MicroRNAs are exported from malignant cells in customized particles, Jaime Palma, Scree C. Yaddanapudi, Lucy Pigati, Mallory A. Havens, Sarah Jeong, Geoffrey A. Weiner, Kristina Mary Ellen Weimer, Brittany Stern, Michelle L. Hastings, and Dominik M. Duelli

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Meeting the need for regenerative therapies I: Target-based incidence and its relationship to U.S spending, productivity, and innovation, Nancy Parenteau, Janet Hardin-Young, William Shannon, Patrick Cantini, and Alan Russell

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High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery, Dhara A. Patel, Anand C. Patel, William C. Nolan, Yong Zhang, and Michael J. Holtzman

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Antiangiogenic and anticancer molecules in cartilage, Debabrata Patra and Linda J. Sandell

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Multi-Institutional experience with FOLFIRINOX in pancreatic adenocarcinoma, Parvin F. Peddi, Sam Lubner, Robert McWilliams, Benjamin R. Tan, Joel Picus, Steven M. Sorscher, Rama Suresh, A Craig Lockhart, Jian Wang, Christine Menias, Feng Gao, David Linehan, and Andrea Wang-Gilliam

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The hemispheric lateralization of speech processing depends on what "speech" is: A hierarchical perspective, Jonathan E. Peelle

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The trauma patient in hemorrhagic shock: How is the C-priority addressed between emergency and ICU admission?, Sigune Peiniger, Thomas Paffrath, Manuel Mutschler, Thomas Brockamp, Matthew Borgmann, Philip C. Spinella, Bertil Bouillon, Marc Maegele, and TraumaRegister DGU

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Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder, M. L. Pergadia and et al

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Active reward processing during human sleep: Insights from sleep-related eating disorder, Lampros Perogamvros, Patrick Baud, Roland Hasler, Claude Robert Cloninger, Sophie Schwartz, and Stephen Perrig

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Multi-institutional analysis of robot-assisted partial nephrectomy for renal tumors >4 cm versus ≤4 cm in 445 consecutive patients, Firas Petros, Shyam Sukumar, Georges-Pascal Haber, Lori Dulabon, Sam Bhayani, Michael Stifelman, Jihad Kaouk, and Craig Rogers

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Whole genome sequence of Treponema pallidum ssp. pallidum, strain Mexico A, suggests recombination between yaws and syphilis strains, Helena Petrosova, Maria Zobanikova, Darina Cejkova, Lenka Mikalova, Petra Pospisilova, Michal Strouhal, Lei Chen, Xiang Qin, Donna M. Muzny, George M. Weinstock, and David Smajs

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The Vermont oxford neonatal encephalopathy registry: Rationale, methods, and initial results, Roger H. Pfister, Peter Bingham, Erika M. Edwards, Jeffrey D. Horbar, Michael J. Kenny, Terrie Inder, Karin B. Nelson, Tonse Raju, and Roger F. Soll

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Early presentation of gait impairment in Wolfram Syndrome, Kristen A. Pickett, Ryan P. Duncan, James Hoekel, Bess Marshall, Tamara Hershey, Gammon M. Earhart, and Washington University Wolfram Study Group

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Acute Respiratory Distress Syndrome: Pathophysiology and therapeutic options, Charalampos Pierrakos, Menelaos Karanikolas, Sabino Scolletta, Vasilios Karamouzos, and Dimitrios Velissaris

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Data sharing in neuroimaging research, Jean-Baptiste Poline, Janis L. Breeze, Satrajit Ghosh, Krzysztof Gorgolewski, Yaroslav O. Halchenko, Michael Hanke, Christian Haselgrove, Karl G. Helmer, David B. Keator, Daniel S. Marcus, Russell A. Poldrack, Yannick Schwartz, John Ashburner, and David N. Kennedy

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Hunter-gatherer energetics and human obesity, Herman Pontzer, David A. Raichlen, Brian M. Wood, Audax Z. P. Mabulla, Susan B. Racette, and Frank W. Marlowe

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A cross-species analysis of microRNAs in the developing avian face, Kara E. Powder, Yuan-Chieh Ku, Samantha A. Brugmann, Rose A. Veile, Nicole A. Renaud, Jill A. Helms, and Michael Lovett

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Cost-effectiveness of peer-delivered interventions for cocaine and alcohol abuse among women: A randomized controlled trial, Jennifer Prah Ruger, Arbi Ben Abdallah, Craig Luekens, and Linda Cottler

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Cancer control needs of 2-1-1 callers in Missouri, North Carolina, Texas, and Washington, Jason Q. Purnell, Matthew W. Kreuter, Katherine S. Eddens, Kurt M. Ribisl, Peggy Hannon, Rebecca S. Williams, Marie E. Fernandez, David Jobe, Susan Gemmel, Marti Morris, and Debbie Fagin

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Retrotransposon profiling of RNA polymerase III initiation sites, Xiaojie Qi, Kenneth Daily, Kim Nguyen, Haoyi Wang, David Mayhew, Paul Rigor, Sholeh Forouzan, Mark Johnston, Robi David Mitra, Pierre Baldi, and Suzanne Sandmeyer

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Advancing the application, quality and harmonization of implementation science measures, Borsika A. Rabin, Peyton Purcell, Sana Naveed, Richard P. Moser, Michelle D. Henton, Enola K. Proctor, Ross C. Brownson, and Russell E. Glasgow

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Medicaid expenditures on psychotropic medications for children in the child welfare system, Ramesh Raghavan, Derek S. Brown, Hope Thompson, Susan L. Ettner, Lisa M. Clements, and Whitney Key