The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2013

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Lamin A Δexon9 mutation leads to telomere and chromatin defects but not genomic instability, Arindam Das, David A. Grotsky, Martin A. Neumann, Ray Kreienkamp, Ignacio Gonzalez-Suarez, Abena B. Redwood, Brian K. Kennedy, Colin L. Stewart, and Susana Gonzalo

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Differential lipid dependence of the function of bacterial sodium channels, Nazzareno D'Avanzo, Emily C. McCusker, Andrew M. Powl, Andrew J. Miles, Colin G. Nichols, and B. A. Wallace

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mBLAST: Keeping up with the sequencing explosion for (meta) genome analysis, Curtis Davis, Karthik Kota, Venkat Baldhandapani, Wei Gong, Sahar Abubucker, Eric Becker, John Martin, Kristine M. Wylie, Radhika Khetani, Matthew E. Hudson, George M. Weinstock, and Makedonka Mitreva

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Aggressive blood pressure control for chronic kidney disease unmasks moyamoya!, T. Keefe Davis, Carmen M. Halabi, Philp Siefken, Swati Karmarkar, and Jeffrey Leonard

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An agent-based modeling template for a cohort of veterans with diabetic retinopathy, Theodore Eugene Day, Nathan Ravi, Hong Xian, and Ann Brugh

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Resting-state functional connectivity emerges from structurally and dynamically shaped slow linear fluctuations, Gustavo Deco, Adrian Ponce Alvarez, Dante Mantini, Gian Luca Romani, Patric Hagmann, and Maurizio Corbetta

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Characterization of the mechanical strength, resorption properties, and histologic characteristics of a fully absorbable material (poly-4-hydroxybutyrate-PHASIX mesh) in a porcine model of hernia repair, Corey R. Deeken and Brent D. Matthews

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Ventralight ST and Sorbafix versus Physiomesh and Securestrap in a porcine model, Corey R. Deeken and Brent D. Matthews

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Cone phosphodiesterase-6α′ restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse, Wen-Tao Deng, Keisuke Sakurai, Saravanan Kolandaivelu, Alexander V. Kolesnikov, Astra Dinculescu, Jie Li, Ping Zhu, Xuan Liu, Jijing Pang, Vince A. Chiodo, Sanford L. Boye, Bo Chang, Visvanathan Ramamurthy, Vladimir J. Kefalov, and William W. Hauswirth

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Evolutionary genomics of the Salmonella enterica subspecies, Prerak T. Desai, Steffen Porwollik, Fred Long, Pui Cheng, Aye Wollam, Sandra W. Clifton, George M. Weinstock, and Michael McClelland

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Genomic and metabolic disposition of non-obese Type 2 Diabetic rats to increased myocardial fatty acid metabolism, Sriram Devanathan, Samuel T. Nemanich, Attila Kovacs, Nicole Fettig, Robert J. Gropler, and Kooresh I. Shoghi

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Antisense reduction of tau in adult mice protects against seizures, Sarah L. DeVos, Dustin K. Goncharoff, Guo Chen, Carey S. Kebodeaux, Kaoru Yamada, Floy R. Stewart, Dorothy R. Schuler, Susan E. Maloney, David F. Wozniak, Frank Rigo, C Frank Bennett, John R. Cirrito, David M. Holtzman, and Timothy M. Miller

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Association of gut microbiota with post-operative clinical course in Crohn’s disease, Neelendu Dey, David AW Soergel, Susanna Repo, and Steven E. Brenner

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Control of cellular Bcl-xL levels by deamidation-regulated degradation, So Hee Dho, Benjamin E. Deverman, Carlo Lapid, Scott R. Manson, Lu Gan, Jacob J. Riehm, Rajeev Aurora, Ki-Sun Kwon, and Steven J. Weintraub

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How phenotype and developmental stage affect the genes we find: GABRA2 and impulsivity, Danielle M. Dick, Fazil Aliev, Shawn Latendresse, Bernice Porjesz, Marc Schuckit, Madhavi Rangaswamy, Victor Hesselbrock, Howard Edenberg, John Nurnberger Jr., Arpana Agrawal, Laura Bierut, Jen Wang, Kathy Bucholz, Samuel Kuperman, and John Kramer

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Point-of-Care glucose analysis in neonates using modified quinoprotein glucose dehydrogenase, Dennis J. Dietzen, Timothy R. Wilhite, Maynard Rasmussen, and Mark Sheffield

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A phase 2 trial of ponatinib in Philadelphia chromosome-positive leukemias, J. DiPersio and et al

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Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I, John F. DiPersio and et al

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Distinct neural signatures detected for ADHD subtypes after controlling for micro-movements in resting state functional connectivity MRI data, Nico U.F. Dosenbach, Bradley L. Schlaggar, and et al

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The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors, Joseph D. Dougherty, Susan E. Maloney, David F. Wozniak, Michael A. Rieger, Lisa Sonnenblick, Giovanni Coppola, Nathaniel G. Mahieu, Juliet Zhang, Jinlu Cai, Gary J. Patti, Brett S. Abrahams, Daniel H. Geschwind, and Nathaniel Heintz

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Body temperature patterns as a predictor of hospital-acquired sepsis in afebrile adult intensive care unit patients: A case-control study, Anne M. Drewry, Brian M. Fuller, Thomas C. Bailey, and Richard S. Hotchkiss

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Counting unstained, confluent cells by modified bright-field microscopy, L. Louis Drey, Michael Graber, and Jan Bieschke

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Transtibial ACL femoral tunnel preparation increases odds of repeat ipsilateral knee surgery, Andrew Duffee, Rober A. Magnussen, Angela D. Pedroza, David C. Flanigan, MOON Group, et al, Rick W. Wright, Matthew J. Matava, and Robert H. Brophy

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Soluble oligomers are sufficient for transmission of a yeast prion but do not confer phenotype, Jennifer E. Dulle, Rachel E. Bouttenot, Lisa A. Underwood, and Heather L. true

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Low activity of select Hsp104 mutants is sufficient to propagate unstable prion variants, Jennifer E. Dulle and Heather L. true

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Genome sequences of three hpAfrica2 strains of Helicobacter pylori, Stacy S. Duncan, M Teresita Bertoli, Dangeruta Kersulyte, Pieter L. Valk, Sravya Tamma, Issy Segal, Mark S. McClain, Timothy L. Cover, and Douglas E. Berg

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IL-1R1 is required for dendritic cell-mediated T cell reactivation within the CNS during West Nile virus encephalitis, Douglas M. Durrant, Michelle L. Robinette, and Robyn S. Klein

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Weekend diagnosis of Escherichia coli urinary tract infection does not predict poor outcome, J. F. Echaiz, J. P. Henderson, D. K. Warren, and J. Marschall

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Physiological role of the interaction between CARMIL1 and capping protein, Marc Edwards, Yun Liang, Taekyung Kim, and John A. Cooper

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The relationship between resilience and personality traits in doctors: Implications for enhancing well being, Diane S. Eley, C. Robert Cloninger, Lucie Walters, Caroline Laurence, Robyn Synnott, and David Wilkinson

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ZRT1 harbors an excess of nonsynonymous polymorphism and shows evidence of balancing selection in Saccharomyces cerevisiae, Elizabeth K. Engle and Justin C. Fay

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RNA helicase signaling is critical for type I interferon production and protection against rift valley fever virus during mucosal challenge, Megan E. Ermler, Ekaterina Yerukhim, Jill Schriewer, Stefan Schattgen, Zachary Traylor, Adam R. Wespiser, Daniel R. Caffrey, Zhijian J. Chen, Charles H. King, Michael Gale Jr., Marco Colonna, Katherine A. Fitzgerald, R. Mark L. Buller, and Amy G. Hise

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The essential, nonredundant roles of RIG-I and MDA5 in detecting and controlling west nile virus infection, John S. Errett, Mehul S. Suthar, Aimee Mcmillan, Michael S. Diamond, and Michael Gale Jr

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HIV-Infected Adolescent, Young Adult and Pregnant Smokers: Important Targets for Effective Tobacco Control Programs, Gerome Escota and Nur Önen

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Katanin localization requires triplet microtubules in Chlamydomonas reinhardtii, Jessica M. Esparza, Eileen O'Toole, Linya Li, Thomas H. Giddings Jr., Benjamin Kozak, Alison J. Albee, and Susan K. Dutcher

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Retrotransposition of gene transcripts leads to structural variation in mammalian genomes, Adam D. Ewing, Tracy J. Ballinger, Dent Earl, Broad Institute Genome Sequencing and Analysis Program and Platform, Christopher C. Harris, Li Ding, Richard K. Wilson, and David Haussler

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Myocardial ablation of G protein–coupled receptor kinase 2 (GRK2) decreases ischemia/reperfusion injury through an anti-intrinsic apoptotic pathway, Qian Fan, Mai Chen, Lin Zou, Xiying Shang, Maggie Z. Huang, Michele Ciccarelli, Philip Raake, Henriette Brinks, Kurt J. Chuprun, Gerald W. Dorn II, Walter J. Koch, and Erhe Gao

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Development of a modified head and neck quality assurance phantom for use in stereotactic radiosurgery trials, Austin M. Faught, Stephen F. Kry, Dershan Luo, Andrea Molineu, David Bellezza, Russel L. Gerber, Scott E. Davidson, Walter Bosch, Robert E. Drzymala, Jim Galvin, Robert Timmerman, Jason Sheehan, Michael T. Gillin, Geoffrey S. Ibbot, and David S. Followill

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Disease consequences of human adaptation, Justin C. Fay

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Control the host cell cycle: Viral regulation of the anaphase-promoting complex, Anthony R. Fehr and Dong Yu

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Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits, Mary F. Feitosa, Aldi T. Kraja, Michael A. Province, and et al

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Changes in auditory perceptions and cortex resulting from hearing recovery after extended congenital unilateral hearing loss, Jill B. Firszt, Ruth M. Reeder, Timothy A. Holden, Harold Burton, and Richard A. Chole

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Serological diagnosis of North American paragonimiasis by western blot using Paragonimus kellicotti adult worm antigen, Peter U. Fischer, Kurt C. Curtis, Scott M. Folk, Patricia P. Wilkins, Luis A. Marcos, and Gary J. Weil

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Transmission assessment surveys (TAS) to define endpoints for lymphatic filariasis mass drug administration: A multicenter evaluation, Peter U. Fischer, Ramakrishna U. Rao, and et al

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Acute care costs in overweight children: a pediatric urban cohort study, Katherine E. Fleming-Dutra, Jingnan Mao, and Julie C. Leonard

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Dietary protein restriction inhibits tumor growth in human xenograft models of prostate and breast cancer, Luigi Fontana, Remi M. Adelaiye, Antonella L. Rastelli, Kiersten Marie Miles, Eric Ciamporcero, Valter D. Longo, Holly Nguyen, Robert Vessella, and Roberto Pili

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Optimization of routine identification of clinically relevant gram-negative bacteria by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and the bruker biotyper, Bradley A. Ford and Carey-Ann D. Burnham

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AhrC and Eep are biofilm infection-associated virulence factors in enterococcus faecalis, Kristi L. Frank, Pascale S. Guiton, Aaron M T Barnes, Dawn A. Manlas, Olivia N. Chuang-Smith, Petra L. Kohler, Adam R. Spaulding, Scott J. Hultgren, Patrick M. Schievert, and Gary M. Dunny

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Targeted versus universal decolonization to prevent ICU infection, Victoria J. Fraser and et al

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Depression as a risk factor for adverse outcomes in coronary heart disease, Kenneth E. Freedland and Robert M. Carney

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Mupirocin and chlorhexidine resistance in Staphylococcus aureus in patients with community-onset skin and soft tissue infections, Stephanie A. Fritz, Patrick G. Hogan, Bernard C. Camins, Ali J. Ainsworth, Carol Patrick, Madeline S. Martin, Melissa J. Krauss, Marcela Rodriguez, and Carey-Ann D. Burnham

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Digit Replantation: Experience of two U.S. academic level-I trauma centers, Duretti Fufa, Ryan Calfee, Lindley Wall, Wenjing Zeng, and Charles Goldfarb

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Lower tidal volume at initiation of mechanical ventilation may reduce progression to acute respiratory distress syndrome: A systematic review, Brian M. Fuller, Nicholas M. Mohr, Anne M. Drewry, and Christopher R. Carpenter

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Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction, Ming Fu, Solange Landreville, Olga A. Agapova, Luke A. Wiley, Michael Shoykhet, J. William Harbour, and Robert O. Heuckeroth

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Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling, Katsuhiko Funai, Haowei Song, Li Yin, Irfan J. Lodhi, Xiaochao Wei, Jun Yoshino, Trey Coleman, and Clay F. Semenkovich

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A pharmacogenetic versus a clinical algorithm for warfarin dosing, Brian F. Gage, Charles S. Eby, and et al

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Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA, Roberto Galletto and Eric J. Tomko

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To the root of the curl: A signature of a recent selective sweep identifies a mutation that defines the Cornish Rex cat breed, Barbara Gandolfi, Hasan Alhaddad, Verena K. Affolter, Jeffrey Brockman, Jens Haggstrom, Shannon E. K. Joslin, Amanda L. Koehne, James C. Mullikin, Catherine A. Outerbridge, Wesley C. Warren, and Leslie A. Lyons

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Esophageal sphincter device for gastroesophageal reflux disease, Robert A. Ganz, Jeffrey H. Peters, Santiago Horgan, Willem A. Bemelman, Christy M. Dunst, Steven A. Edmundowicz, John C. Lipham, James D. Luketich, W. Scott Melvin, Brant K. Oelschlager, Steven C. Schlack-Haerer, C. Daniel Smith, Christopher C. Smith, Dan Dunn, and Paul A. Taiganides

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Temperament and character in the Child and Adolescent Twin Study in Sweden (CATSS): Comparison to the general population, and genetic structure analysis, Danilo Garcia, Sebastian Lundstrom, Sven Brandstrom, Maria Rastam, C. Robert Cloninger, Nora Kerekes, Thomas Nilsson, and Henrik Anckarsater

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HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders, Emmanuel L. Gautier, Marit Westerterp, Neha Bhagwat, Serge Cremers, Alan Shih, Omar Abdel-Wahab, Dieter Lütjohann, Gwendalyn J. Randolph, Ross L. Levine, Alan R. Tall, and Laurent Yvan-Charvet

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Modeling of non-small cell lung cancer volume changes during CT-based image guided radiotherapy: patterns observed and clinical implications, Hiram A. Gay, Quendella Q. Taylor, Fumika Kiriyama, Geoffrey T. Dieck, Todd Jenkins, Paul Walker, Ron R. Allison, and Paolo Ubezio

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Sarm1-mediated axon degeneration requires both SAM and TIR interactions, Josiah Gerdts, Daniel W. Summers, Yo Sasaki, Aaron DiAntonio, and Jeffrey Milbrandt

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Adrenal myelolipoma: Operative indications and outcomes, Victoria M. Gershuni, James G. Bittner IV, Jeffrey F. Moley, and L. Michael Brunt

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The quest for load‐independent left ventricular chamber properties: Exploring the normalized pressure phase plane, Erina Ghosh and Sandor J. Kovacs

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Training the workforce in evidence-based public health: An evaluation of impact among US and international practitioners, Wesley S. Gibbert, Shannon M. Keating, Julie A. Jacobs, Elizabeth Dodson, Elizabeth Baker, Gunter Diem, Wayne Giles, Kathleen N. Gillespie, Vilius Grabauskas, Aushra Shatchkute, and Ross C. Brownson

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Results of the two incidence screenings in the National Lung Screening Trial, David S. Gierada and et al

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Clinical features of bacterial vaginosis in a murine model of vaginal infection with Gardnerella vaginalis, Nicole M. Gilbert, Warren G. Lewis, and Amanda L. Lewis

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Loss of DAP12 and FcRγ drives exaggerated IL-12 production and CD8(+) T cell response by CCR2(+) Mo-DCs, Grzegorz B. Gmyrek, Holly M. Akilesh, Daniel B. Graham, Anja Fuchs, Lihua Yang, Mark J. Miller, Gabriel J. Sandoval, Kathleen C. F. Sheehan, Robert D. Schreiber, Michael S. Diamond, and Wojciech Swat

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Efficiency of first-trimester uterine artery Doppler, A-disintegrin and metalloprotease 12, pregnancy-associated plasma protein A, and maternal characteristics in the prediction of preeclampsia, Katherine R. Goetzinger, Yan Zhong, Alison G. Cahill, Linda Odibo, George A. Macones, and Anthony O. Odibo

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Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons, Judith P. Golden, Joseph A. DeMaro III, Amanda Knoten, Masato Hoshi, Elizabeth Pehek, Eugene M. Johnson Jr, Robert W. Gereau IV, and Sanjay Jain

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Transcription factors define the neuroanatomical organization of the medullary reticular formation, Paul A. Gray

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Modeling precision treatment of breast cancer, Obi L. Griffith, Malachi Griffith, and et al

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A robust prognostic signature for hormone-positive node-negative breast cancer, Obi L. Griffith, Francois Pepin, Oana M. Enache, Laura M. Heiser, Eric A. Collisson, Paul T. Spellman, and Joe W. Gray

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BRCA1 loss activates cathepsin L–mediated degradation of 53BP1 in breast cancer cells, David A. Grotsky, Ignacio Gonzalez-Suarez, Anna Novell, Martin A. Neumann, Sree C. Yaddanapudi, Monica Croke, Montserrat Martinez-Alonso, Abena B. Redwood, Sylvia Ortega-Martinez, Zhihui Feng, Enrique Lerma, Teresa Ramon y Cajal, Junran Zhang, Xavier Matias-Guiu, Adriana Dusso, and Susana Gonzalo

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Acute EBV infection masquerading as "In-situ Follicular Lymphoma": A pitfall in the differential diagnosis of this entity, Alejandro A. Gru, Friederike Kreisel, Eric Duncavage, TuDung T. Nguyen, Anjum Hassan, and John L. Frater

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Concurrent malignant melanoma and cutaneous involvement by classical hodgkin lymphoma (CHL) in a 63 year-old man, Alejandro A. Gru and Dongsi Lu

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Longitudinal changes in intracardiac repolarization lability in patients with implantable cardioverter-defibrillator, Abhilash Guduru, Jason Lansdown, Daniil Chernichenko, Ronald D. Berger, and Larisa G. Tereshchenko

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CMS: A web-based system for visualization and analysis of genome-wide methylation data of human cancers, Fei Gu, Mark S. Doderer, Yi-Wen Huang, Juan C. Roa, Paul J. Goodfellow, E. Lynette Kizer, Tim H. M. Huang, and Yidong Chen

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Enterococcus faecalis overcomes foreign body-mediated inflammation to establish urinary tract infections, Pascale S. Guiton, Thomas J. Hannan, Bradley Ford, Michael G. Caparon, and Scott J. Hultgren

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Postradiation osteosarcoma in an older prostate cancer survivor: Case study and literature review with emphasis on geriatric principles, Divya Gumber, Miriam Rodin, and Tanya M. Wildes

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Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury, Dongjun Guo, Linghui Zeng, David L. Brody, and Michael Wong

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Reliability of clinically relevant 3D foot bone angles from quantitative computed tomography, David J. Gutekunst, Lu Liu, Tao Ju, Fred W. Prior, and David R. Sinacore

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Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma, David H. Gutmann, Michael D. McLellan, Ibrahim Hussain, John W. Wallis, Lucinda L. Fulton, Robert S. Fulton, Vincent Magrini, Ryan Demeter, Todd Wylie, Cyriac Kandoth, Jeffrey R. Leonard, Abhijit Guha, Christopher A. Miller, Li Ding, and Elaine R. Mardis

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Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study, Jenni Hällfors, Anu Loukola, Janne Pitkäniemi, Ulla Broms, Satu Männistö, Veikko Salomaa, Markku Heliövaara, Terho Lehtimäki, Olli Raitakari, Pamela AF Madden, Andrew C. Heath, Grant W. Montgomery, Nicholas G. Martin, Tellervo Korhonen, and Jaakko Kaprio

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Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif, Mark P. Hamilton, Kimal Rajapakshe, Sean M. Hartig, Boris Reva, Michael D. McLellan, Cyriac Kandoth, Li Ding, Travis I. Zack, Preethi H. Gunaratne, David A. Wheeler, Cristian Coarfa, and Sean E. McGuire

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Use of brain electrical activity for the identification of hematomas in mild traumatic brain injury, David F. Hanley, Robert Chabot, W. Andrew Mould, Timothy Morgan, Rosanne Naunheim, Kevin N. Sheth, William Chiang, and Leslie S. Prichep

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Exosomes: Looking back three decades and into the future, Clifford V. Harding, John E. Heuser, and Philip D. Stahl

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Sonographic accuracy of estimated fetal weight in twins, Lorie M. Harper, Kimberly A. Roehl, Methodius G. Tuuli, Anthony O. Odibo, and Alison G. Cahill

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Local health department use of Twitter to disseminate diabetes information, United States, Jenine K. Harris, Nancy L. Mueller, Doneisha Snider, and Debra Haire-Joshu

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Retrophylogenomics place tarsiers on the evolutionary branch of anthropoids, Gerrit Hartig, Gennady Churakov, Wesley C. Warren, Jürgen Brosius, Wojciech Makalowski, and Jürgen Schmitz

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Molecular characterization of articular cartilage from young adults with femoroacetabular impingement, Shingo Hashimoto, Muhammad Farooq Rai, Corey S. Gill, Zhiqi Zhang, Linda J. Sandell, and John C. Clohisy

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Progression of foot deformity in charcot neuropathic osteoarthropathy, Mary K. Hastings, Jeffrey E. Johnson, Michael J. Strube, Charles F. Hildebolt, Kathryn L. Bohnert, Fred W. Prior, and David R. Sinacore

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Chronic joint disease caused by persistent Chikungunya virus infection is controlled by the adaptive immune response, David W. Hawman, Kristina A. Stoermer, Stephanie A. Montgomery, Pankaj Pal, Lauren Oko, Michael S. Diamond, and Thomas E. Morrison

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Mapping functional transcription factor networks from gene expression data, Brian C. Haynes, Ezekiel J. Maier, Michael H. Kramer, Patricia I. Wang, Holly Brown, and Michael R. Brent

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The role of adiposity in cardiometabolic traits: A Mendelian randomization analysis, Andrew C. Heath, Pamela A. F. Madden, and et al

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Average is optimal: An inverted-U relationship between trial-to-trial brain activity and behavioral performance, Biyu J. He and John M. Zempel

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Determinants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: A computational analysis, Jordi Heijman, Antonio Zaza, Daniel M. Johnson, Yoram Rudy, Ralf L. M. Peeters, Paul G. A. Volders, and Ronald L. Westra

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Transcriptome analyses reveal protein and domain families that delineate stage-related development in the economically important parasitic nematodes, Ostertagia ostertagi and Cooperia oncophora, Esley Heizer, Dante S. Zarlenga, Bruce Rosa, Xin Gao, Robin B. Gasser, Jessie De Graef, Peter Geldhof, and Makedonka Mitreva

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Isolation and characterization of the herpes simplex virus 1 terminase complex, Jason D. Heming, Jamie B. Huffman, Lisa M. Jones, and Fred L. Homa