The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU

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Submissions from 2012

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Postprandial leucine and insulin responses and toxicological effects of a novel whey protein hydrolysate-based supplement in rats, Ryan G. Toedebusch, Thomas E. Childs, Shari R. Hamilton, Jan R. Crowley, Frank W. Booth, and Michael D. Roberts

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Mechanistic characterization of the 5′-triphosphate-dependent activation of PKR: Lack of 5′-end nucleobase specificity, evidence for a distinct triphosphate binding site, and a critical role for the dsRBD, Rebecca Toroney, Chelsea M. Hull, Joshua E. Sokoloski, and Philip C. Bevilacqua

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Prospects for a novel ultrashort pulsed laser technology for pathogen inactivation, Shaw-Wei D. Tsen, Tzyy C. Wu, Juliann G. Kiang, and Kong-Thon Tsen

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Functional assessment of human coding mutations affecting skin pigmentation using zebrafish, Zurab R. Tsetskhladze, Victor A. Canfield, Khai C. Ang, Steven M. Wentzel, Katherine P. Reid, Arthur S. Berg, Stephen L. Johnson, Koichi Kawakami, and Keith C. Cheng

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Temperament, character and serotonin activity in the human brain: A positron emission tomography study based on a general population cohort, L. Tuominen, J. Salo, J. Hirvonen, K. Någren, P. Laine, T. Melartin, E. Isometsä, J. Viikari, C. R. Cloninger, O. Raitakari, J. Hietala, and L. Keltikangas-Järvinen

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Optimizing global health experiences in emergency medicine residency programs: A consensus statement from the Council of Emergency Medicine Residency Directors 2011 Academic Assembly global health specialty track, Janis P. Tupesis, Christine Babcock, Doug Char, Kumar Alagappan, Braden Hexom, and G. B. Kapur

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Organization of Vomeronasal Sensory Coding Revealed by Fast Volumetric Calcium Imaging, Diwakar Turaga and Timothy E. Holy

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Intermuscular adipose tissue is muscle specific and associated with poor functional performance, Lori J. Tuttle, David R. Sinacore, and Michael J. Mueller

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Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1, Xiaolin Tu, Jianquan Chen, Joohyun Lim, Courtney M. Karner, Seung-Yon Lee, Julia Heisig, Cornelia Wiese, Kameswaran Surendran, Raphael Kopan, Manfred Gessler, and Fanxin Long

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A first step in determining appropriate amounts of obstetric anesthesia work, Swarup S. Varaday and Barbara L. Leighton

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Potential implications of HCN channel dysfunction after subarachnoid hemorrhage, Ananth K. Vellimana

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The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2, Mario Ventura, Claudia R. Catacchio, Saba Sajjadian, Laura Vives, Peter H. Sudmant, Tomas Marques-Bonet, Tina A. Graves, Richard K. Wilson, and Evan E. Eichler

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β-cell metabolic alterations under chronic nutrient overload in rat and human islets, Stephanie Vernier, Angela Chiu, Joseph Schober, Theresa Weber, Phuong Nguyen, Mark Luer, Timothy McPherson, Paul E. Wanda, Connie A. Marshall, Nidhi Rohatgi, Michael L. McDaniel, Andrew S. Greenberg, and Guim Kwon

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Lenalidomide after stem-cell transplantation for multiple myeloma, Ravi Viji and et al

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Recent advances in chronic lymphocytic leukemia, N. Vyas and A. Hassan

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TBC1D3, a hominoid-specific gene, delays IRS-1 degradation and promotes insulin signaling by modulating p70 S6 kinase activity, Marisa J. Wainszelbaum, Jialu Liu, Chen Kong, Priya Srikanth, Dmitri Samovski, Xiong Su, and Philip D. Stahl

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Diagnostic performance and reliability of ultrasonography for fatty degeneration of the rotator cuff muscles, Lindley B. Wall, Sharlene A. Teefey, William D. Middleton, Nirvikar Dahiya, Karen Steger-May, H. Mike Kim, Daniel Wessell, and Ken Yamaguchi

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Overcoming phase 1 delays: The critical component of obstetric fistula prevention programs in resource-poor countries, L. Lewis Wall

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Clonal architecture of secondary acute myeloid leukemia, Matthew J. Walter, Dong Shen, Li Ding, Jin Shao, Daniel C. Koboldt, Ken Chen, David E. Larson, Michael D. McLellan, David Dooling, Rachel Abbott, Robert Fulton, Vincent Magrini, Heather Schmidt, Joelle Kalicki-Veizer, Michelle O'Laughlin, Xian Fan, Marcus Grillot, Sarah Witowski, Sharon Heath, John L. Frater, William Eades, Michael Tomasson, Peter Westervelt, John F. DiPersio, Daniel C. Link, Elaine R. Mardis, Timothy J. Ley, Richard K. Wilson, and Timothy A. Graubert

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ATG16L1 and pathogenesis of urinary tract infections, Caihong Wang, Jane W. Symington, and Indira U. Mysorekar

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PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection, Qiang Wang, Shijian Zhang, Hongbing Jiang, Jinlan Wang, Leiyun Weng, Yingying Mao, Satoshi Sekiguchi, Fumihiko Yasui, Michinori Kohara, Philippe Buchy, Vincent Deubel, Ke Xu, Bing Sun, and Tetsuya Toyoda

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Network analysis of corticocortical connections reveals ventral and dorsal processing streams in mouse visual cortex, Quanxin Wang, Olaf Sporns, and Andreas Burkhalter

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Structural rearrangements underlying ligand-gating in Kir channels, Shizhen Wang, Sun-Joo Lee, Sarah Heyman, Decha Enkvetchakul, and Colin G. Nichols

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Aflibercept in the treatment of metastatic colorectal cancer, Tzu-Fei Wang and Albert Craig Lockhart

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PrimerBank: A PCR primer database for quantitative gene expression analysis, 2012 update, Xiaowei Wang, Athanasia Spandidos, Huajun Wang, and Brian Seed

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Exploring metazoan evolution through dynamic and holistic changes in protein families and domains, Zhengyuan Wang, Dante Zarlenga, John Martin, Sahar Abubucker, and Makedonka Mitreva

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Gastrointestinal lymphomas in a North American population: Clinicopathologic features from one major Central-Midwestern United States tertiary care medical center, Joshua Warrick, Jingqin Luo, Diane Robirds, Julie Branson, John L. Frater, Friederike Kreisel, Anjum Hassan, and TuDung T. Nguyen

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Expression and function of PML-RARA in the hematopoietic progenitor cells of Ctsg-PML-RARA mice, Lukas D. Wartman, John S. Welch, Geoffrey L. Uy, Jeffery M. Klco, Tamara Lamprecht, Nobish Varhese, Rakesh Nagarajan, and Timothy J. Ley

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Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking, Anita A. Wasik, Zydrune Polianskyte-Prause, Meng-Qiu Dong, Andrey S. Shaw, John R. Yates III, Marilyn G. Farquhar, and Sanna Lehtonen

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Deconvoluting mTOR biology, Jason D. Weber and David H. Gutmann

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Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesis, Leslie A. Weiss, Phillip G. Harrison, Bryce E. Nickels, Michael S. Glickman, Elizabeth A. Campbell, Seth A. Darst, and Christina L. Stallings

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Colony organization in the green alga Botryococcus braunii (Race B) is specified by a complex extracellular matrix, Taylor L. Weiss, Robyn Roth, Carrie Goodson, Stanislav Vitha, Ian Black, Parastoo Azadi, Jannette Rusch, Andreas Holzenburg, Timothy P. Devarenne, and Ursula Goodenough

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Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception, Yingqi Weng, Patricia A. Batista-Schepman, Marie E. Barabas, Eli Q. Harris, Thomas B. Dinsmore, Elena A. Kossyreva, Audra M. Foshage, Michelle H. Wang, Matthew J. Schwab, Victoria M. Wang, Cheryl L. Stucky, and Gina M. Story

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Strategic insight and age-related goal-neglect influence risky decision-making, Andrew Westbrook, Bruna S. Martins, Tal Yarkoni, and Todd S. Braver

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Peripheral-blood stem cells versus bone marrow from unrelated donors, Peter Westervelt and et al

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A model of spatially restricted transcription in opposing gradients of activators and repressors, Michael A. White, Davis S. Parker, Scott Barolo, and Barak A. Cohen

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Enzyme-replacement therapy in life-threatening hypophosphatasia, Michael P. Whyte, William H. McAlister, and et al

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Absence of Ca2+-stimulated adenylyl cyclases leads to reduced synaptic plasticity and impaired experience-dependent fear memory, L. Wieczorek, D. Majumdar, T. A. Wills, L. Hu, D. G. Winder, D. J. Webb, and L. J. Muglia

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In vivo human apolipoprotein E isoform fractional turnover rates in the CNS, Kristin R. Wildsmith, Jacob M. Basak, Bruce W. Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E. Yarasheski, Jennifer X. Wang, Kwasi G. Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C. Sigurdson, Chengjie Xiong, Alison Goate, David M. Holtzman, and Randall J. Bateman

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Dendritic cell based PSMA immunotherapy for prostate cancer using a CD40-targeted adenovirus vector, Briana Jill Williams, Shilpa Bhatia, Lisa K. Adams, Susan Boling, Jennifer L. Carroll, Xiao-Lin Li, Donna L. Rogers, Nikolay Korokhov, Imre Kovesdi, Alexander V. Pereboev, David T. Curiel, and Michael Mathis

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No evidence of xenotropic murine leukemia virus-related virus transmission by blood transfusion from infected rhesus macaques, Dhanya K. Williams, Teresa A. Galvin, Yamei Gao, Christina O'Neill, Dustin Glasner, and Arifa S. Khan

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Effectiveness of long-acting reversible contraception, Brooke Winner, Jeffrey F. Peipert, Quihong Zhao, Christina Buckel, Tessa Madden, Jenifer E. Allsworth, and Gina M. Secura

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Promoting physical activity in patients with colon adenomas: a randomized pilot intervention trial, Kathleen Y. Wolin, Casey Fagin, Aimee S. James, and Dayna S. Early

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Childhood school segregation and later life sense of control and physical performance in the African American Health cohort, Fredric D. Wolinsky, Elena M. Andresen, Theodore K. Malmstrom, J. P. Miller, Mario Schootman, and Douglas K. Miller

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The coronary CT angiography vision protocol: A prospective observational imaging cohort study in patients undergoing non-cardiac surgery, Pamela K. Woodard and et al

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Coronary CT angiography versus standard evaluation in acute chest pain, Pamela Woodard, Michael E. Mullins, and et al

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Outcome of revision anterior cruciate ligament reconstruction: a systematic review, Rick W. Wright, Corey S. Gill, Ling Chen, Robert H. Brophy, Matthew J. Matava, Matthew V. Smith, and Nathan A. Mall

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Synaptic NMDA receptors mediate hypoxic excitotoxic death, Christine M. Wroge, Joshua Hogins, Larry Eisenman, and Steven Mennerick

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Chemokine GPCR signaling inhibits beta-catenin during Zebrafish axis formation, Shu-Yu Wu, Jimann Shin, Diane S. Sepich, and Lilianna Solnica-Krezel

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Sequence analysis of the human virome in febrile and afebrile children, Kristine M. Wylie, Kathie A. Mihindukulasuriya, Erica Sodergren, George M. Weinstock, and Gregory A. Storch

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Novel bacterial taxa in the human microbiome, Kristine M. Wylie, Rebecca M. Truty, Thomas J. Sharpton, Kathie A. Mihindukulasuriya, Yanjiao Zhou, Hongyu Gao, Erica Sodergren, George M. Weinstock, and Katherine S. Pollard

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Bcl-x Pre-mRNA splicing regulates brain injury after neonatal hypoxia-ischemia, Qingli Xiao, Andria L. Ford, Jan Xu, Ping Yan, Kuang-Yung Lee, Ernesto Gonzales, Tim West, David M. Holtzman, and Jin-Moo Lee

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Role of the Skp1 prolyl-hydroxylation/ glycosylation pathway in oxygen dependent submerged development of Dictyostelium, Yuechi Xu, Zhuo A. Wang, Rebekah S. Green, and Christopher M. West

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Social, economic, and resource predictors of variability in household air pollution from cookstove emissions, Gautam N. Yadama, John Peipert, Manoranjan Sahu, Pratim Biswas, and Venkat Dyda

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18FDG PET-CT imaging detects arterial inflammation and early atherosclerosis in HIV-infected adults with cardiovascular disease risk factors, Kevin E. Yarasheski, Erin Laciny, E. T. Overton, Dominic N. Reeds, Michael Harrod, Steven Baldwin, and Victor G. Davila-Roman

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Auricular point acupressure for chronic low back pain: A feasibility study for 1-week treatment, Chao-Hsing Yeh, Lung-Chang Chien, Yi-Chien Chiang, and Li-Chun Huang

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Reduction in nausea and vomiting in children undergoing cancer chemotherapy by either appropriate or sham auricular acupuncture points with standard care, Chao Hsing Yeh, Lung-Chang Chien, Yi Chien Chiang, Su Wen Lin, Chen Kuan Huang, and Dianxu Ren

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Geminin regulates the transcriptional and epigenetic status of neuronal fate-promoting genes during mammalian neurogenesis, Dhananjay Yellajoshyula, Jong-won Lim, Dominic M. Thompson, Jacob S. Witt, Ethan S. Patterson, and Kristen L. Kroll

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Neonatal diethylstilbestrol exposure alters the metabolic profile of uterine epithelial cells, Yan Yin, Congxing Lin, G. Michael Veith, Hong Chen, Maulik Dhandha, and Liang Ma

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Enhanced surgical site infection surveillance following hysterectomy, vascular, and colorectal surgery, Deborah S. Yokoe, Yosef Khan, Margaret A. Olsen, David C. Hooper, Maurice Greenbaum, Johanna Vostok, Julie Lankiewicz, Victoria J. Fraser, and Kurt B. Stevenson

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Adaptive immunity restricts replication of novel murine astroviruses, Christine C. Yokoyama, Joy Loh, Guoyan Zhao, Thaddeus S. Stappenbeck, David Wang, Henry V. Huang, Herbert W. Virgin, and Larissa B. Thackray

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WormBase 2012: More genomes, more data, new website, Karen Yook, Tamberlyn Bieri, Bill Nash, Philip Ozersky, and John Spieth

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A systematic study of gene expression variation at single-nucleotide resolution reveals widespread regulatory roles for uAUGs, Yue Yun, T.M. Ayodele Adesanya, and Robi D. Mitra

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A critical cell-intrinsic role for serum response factor in glial specification in the CNS, Paul P.Y. Yu and Narendrakumar Ramanan

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Detection thresholds of macaque otolith afferents, Xiong-Jie Yu, J David Dickman, and Dora E. Angelaki

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Two-year outcomes after transcatheter or surgical aortic-valve replacement, Alan Zajarias and et al

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Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis, Linda Zane, Junichiro Yasunaga, Yu Mitagami, Venkat Yedavalli, Sai-Wen Tang, Chia-Yen Chen, Lee Ratner, Xiongbin Lu, and Kuan-Teh Jeang

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Characterization of scale-free properties of human electrocorticography in awake and slow wave sleep states, John M. Zempel, David G. Politte, Matthew Kelsey, Ryan Verner, Tracy S. Nolan, Abbas Babajani-Feremi, Fred Prior, and Linda J. Larson-Prior

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Sigma-2 ligands induce tumour cell death by multiple signalling pathways, Chenbo Zeng, Justin M. Rothfuss, Jun Zhang, Wenhua Chu, Suwanna Vangveravong, Zhude Tu, Fenghui Pan, Katherine Chang, Richard S. Hotchkiss, and Robert H. Mach

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Near infrared imaging of EGFR of oral squamous cell carcinoma in mice administered arsenic trioxide, Lingbo Zhang, Kezheng Wang, Falin Zhao, Weiping Hu, Junjie Chen, Gregory M. Lanza, Baozhong Shen, and Bin Zhang

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Genome-wide analysis of plant nat-siRNAs reveals insights into their distribution, biogenesis and function, Xiaoming Zhang, Jing Xia, Yifan E. Lii, Blanca E. Barrera-Figueroa, Xuefeng Zhou, Shang Gao, Lu Lu, Dongdong Niu, Zheng Chen, Christy Leung, Timothy Wong, Huiming Zhang, Jianhua Guo, Yi Li, Renyi Liu, Wanqi Liang, Jian-Kang Zhu, Weixiong Zhang, and Hailing Jin

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Image quality analysis of high-density diffuse optical tomography incorporating a subject-specific head model, Yuxuan Zhan, Adam T. Eggebrecht, Joseph P. Culver, and Hamid Dehghani

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Singular value decomposition based regularization prior to spectral mixing improves crosstalk in dynamic imaging using spectral diffuse optical tomography, Yuxuan Zhan, Adam T. Eggebrecht, Joseph P. Culver, and Hamid Dehghani

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Conserved motifs and prediction of regulatory modules in Caenorhabditis elegans, Guoyan Zhao, Nnamdi Ihuegbu, Mo Lee, Larry Schriefer, Ting Wang, and Gary D. Stormo

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Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophy, D. Zhi, M. R. Irvin, C. C. Gu, A. J. Stoddard, R. Lorier, A. Matter, D. C. Rao, V Srinivasasainagendra, H. K. Tiwari, A. Turner, U. Broeckel, and D. K. Arnett

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Glaucoma-induced degeneration of retinal ganglion cells prevented by hypoxic preconditioning: A model of glaucoma tolerance, Yanli Zhu, Lihong Zhang, Jimena F. Schmidt, and Jeffrey M. Gidday

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Risk factors for mixed complicated skin and skin structure infections to help tailor appropriate empiric therapy, Marya Zilberberg, Scott T. Micek, Marin H. Kollef, Ahmed Shelbaya, and Andrew F. Shorr

Submissions from 2011

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Case-control association testing by graphical modeling for the Genetic Analysis Workshop 17 mini-exome sequence data, Haley J. Abel and Alun Thomas

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Principal component analysis of dynamic relative displacement fields estimated from MR images, Teresa M. Abney, Yuan Feng, Robert Pless, Ruth J. Okamoto, Guy M. Genin, and Philip V. Bayly

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HelmCoP: An online resource for helminth functional genomics and drug and vaccine targets prioritization, Sahar Abubucker, John Martin, Christina M. Taylor, and Makedonka Mitreva

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Effect of obesity, serum lipoproteins, and apolipoprotein E genotypes on mortality in hospitalized elderly patients, Filomena Addante, Daniele Sancarlo, Massimiliano Copetti, Carlo Scarcelli, Maria Grazia Longo, Valeria Niro, Giulia Paroni, Fabio Pellegrini, Luigi Fontana, and Alberto Pilotto

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Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis, Shreeram Akilesh, Hani Suleiman, Christine Stander, Haiyang Yu, Peter Lavin, Rasheed Gbadegesin, Corinne Antignac, Martin Pollack, Jeffrey B. Kopp, Michelle P. Winn, and Andrey S. Shaw

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Exome sequencing identifies an MYH3 mutation in a family with distal arthrogryposis type 1, David M. Alvarado, Jillian G. Buchan, Christina A. Gurnett, and Matthew B. Dobbs

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An RNA interference-based screen of transcription factor genes identifies pathways necessary for sensory regeneration in the avian inner ear, David M. Alvarado, R. D. Hawkins, Stavros Bashiardes, Rose A. Veile, Yuan-Chieh Ku, Kara E. Powder, Meghan K. Spriggs, Judith D. Speck, Mark E. Warchol, and Michael Lovett

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A knock-in mouse model for the R120G mutation of alphaBcrystallin recapitulates human hereditary myopathy and cataracts, Usha P. Andley, Paul D. Hamilton, Nathan Ravi, and Conrad C. Weihl

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Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells, Claudia Andreu-Vieyra, John Lai, Benjamin P. Berman, Baruch Frenkel, Li Jia, Peter A. Jones, and Gerhard A. Coetzee

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Coding of stereoscopic depth information in visual areas V3 and V3A, Akiyuki Anzai, Syed A. Chowdhury, and Gregory C. DeAngelis

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Prevalence of nasal carriage of mupirocin-resistant Staphylococcus aureus among hospitalized patients in Thailand, Anucha Apisarnthanarak, David K. Warren, and Victoria J. Fraser

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Prevention of intraoperative awareness in a high-risk surgical population, Michael S. Avidan, Beth A. Burnside, Lini Zhang, Saima Kamal, Brian Torres, Alex S. Evers, Stephen Gradwohl, Ben J. Palanca, Nan Lin, David Glick, Leah Karl, Michael O'Connor, and George A. Mashour

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Complement-mediated neutralization of dengue virus requires mannose-binding lectin, Panisadee Avirutnan, Richard E. Hauhart, Mary A. Marovich, Peter Garred, John P. Atkinson, and Michael S. Diamond

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Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells, Imran A. Babar, Jennifer Czochor, Allison Steinmetz, Joanne B. Weidhaas, Peter M. Glazer, and Frank J. Slack

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Daily or intermittent budesonide in preschool children with recurrent wheezing, Leonard B. Bacharier, Robert C. Strunk, Avraham Beigelman, and et al

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Cell wall chitosan is necessary for virulence in the opportunistic pathogen Cryptococcus neoformans, Lorina G. Baker, Charles A. Specht, and Jennifer K. Lodge

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Diagnosis and management of fetal growth restriction, Jacqueline E. A. K. Bamfo and Anthony O. Odibo

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Residual Cx45 and its relationship to Cx43 in murine ventricular myocardium, Mingwei Bao, Evelyn M. Kanter, Richard Y.C. Huang, Stephan Maxeiner, Marina Frank, Yan Zhang, Richard B. Schuessler, Timothy W. Smith, R. Reid Townsend, Henry W. Rohrs, Viviana M. Berthoud, Klaus Willecke, James G. Laing, and Kathryn A. Yamada

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OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice, Alexander David Barrow, Marina Cella, Marco Colonna, Nicolas Raynal, Thomas Levin Anderson, David A. Slatter, Dominique Bihan, Nicholas Pugh, Taesoo Kim, Jaerang Rho, Takako Nedishi-Koga, Jean-Marie Delaisse, Hiroshi Takayanagi, Joseph Lorenzo, and et al.

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Human parvovirus 4 as potential cause of encephalitis in children, India, Laura A. Benjamin, Penny Lewthwaite, Ravi Vasanthapuram, Guoyan Zhao, Colin Sharp, Peter Simmonds, David Wang, and Tom Solomon

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A recurrent missense mutation in GJA3 associated with autosomal dominant cataract linked to chromosome 13q, Thomas M. Bennett and Alan Shiels

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Renal tumor models: Evaluation of ease of implementation, quality of composition, and imaging characteristics, Brian M. Benway, Jose M. Cabello, Alana C. Desai, Robert S. Figenshaw, and Sam B. Bhayani

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6-OHDA generated ROS induces DNA damage and p53- and PUMA-dependent cell death, Alison I. Bernstein, Sean P. Garrison, Gerard P. Zambetti, and Karen L. O'Malley