The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.
You can find more information about Washington University's Open Access Resolution in Becker Medical Library's Open Access subject guide “OA Resolution at WU”
Submissions from 2012
Transposon mutagenesis identifies uropathogenic Escherichia coli biofilm factors, Maria Hadjifrangiskou, Alice P. Gu, Jerome S. Pinkner, Maria Kostakioti, Ellisa W. Zhang, Sarah E. Greene, and Scott J. Hultgren
What does it take to stick around?: Molecular insights into biofilm formation by uropathogenic Escherichia coli, Maria Hadjifrangiskou and Scott J. Hultgren
Prevention of musculoskeletal disorders in workers: Classification and health surveillance – statements of the Scientific Committee on Musculoskeletal Disorders of the International Commission on Occupational Health, Mats Hagberg, Francesco Saverio Violante, Roberta Bonfiglioli, Alexis Descatha, Judith Gold, Brad Evanoff, and Judith K. Sluiter
Sodium-activated potassium channels are functionally coupled to persistent sodium currents, Travis A. Hage and Lawrence Salkoff
Development of a novel xenotransplantation strategy for treatment of diabetes mellitus in rat hosts and translation to non-human primates, Marc R. Hammerman
Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways, Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J. Edenberg, Andrew Heath, Nicholas G. Martin, Michele L. Pergadia, Grant Montgomery, Andrew Schrage, Laura J. Bierut, Pamela F. Madden, and Alison M. Goate
Intermediate outcomes following percutaneous fixation of proximal humeral fractures, Alicia K. Harrison, Konrad I. Gruson, Benjamin Zmistowski, Jay Keener, Leesa Galatz, Gerald Williams, Bradford O. Parsons, and Evan L. Flatgow
Role of the polarity protein Scribble for podocyte differentiation and maintenance, Bjorn Hartleben, Eugen Widmeier, Nicola Wanner, Miriam Schmidts, Sung Tae Kim, Lisa Schneider, Britta Mayer, Dontscho Kerjaschki, Jeffrey H. Miner, Gerd Walz, and Tobias B. Huber
Leishmania RNA virus: When the host pays the toll, Mary-Anne Hartley, Catherine Ronet, Haroun Zangger, Stephen M. Beverley, and Nicolas Fasel
Apolipoprotein e, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide, Tadafumi Hashimoto, Alberto Serrano-Pozo, Yukiko Hori, Kenneth W. Adams, Shuko Takeda, Adrian Olaf Banerji, Akinori Mitani, Daniel Joyer, Diana H. Thyssen, Brian J. Bacskai, Matthew P. Frosch, Tara L. Spires-Jones, Mary Beth Finn, David M. Holtzman, and Bradley T. Hyman
Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer’s disease subjects, Saori Hata, Miyako Taniguchi, Yi Piao, Takeshi Ikeuchi, Anne M. Fagan, David M. Holtzman, Randall Bateman, Hamid R. Sohrabi, Ralph N. Martins, Sam Gandy, Katsuya Urakami, Toshiharu Suzuki, and Japanese Alzheimer's Disease Neuroimaging Initiative
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales, A. C. Heath, P. A. F. Madden, and et al
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA, Andrew C. Heath, Pamela A. F. Madden, and et al
Changing epidemiology of methicillin-resistant Staphylococcus aureus colonization in paediatric intensive-care units, C. R. Hermos, T. J. Sandora, L. E. Williams, N. Mosammaparast, and A. J. McAdam
Early brain vulnerability in Wolfram syndrome, Tamara Hershey, Heather M. Lugar, Joshua S. Shimony, Jerrel Rutlin, Jonathan M. Koller, Dana C. Perantie, Alex R. Paciorkowski, Sarah A. Eisenstein, M. Alan Permutt, and Washington University Wolfram Study Group
Production of α-L-iduronidase in maize for the potential treatment of a human lysosomal storage disease, Xu He, Thomas Haselhorst, Mark von Itzstein, Daniel Kolarich, Nicolle H. Packer, Tracey M. Gloster, David J. Vocadlo, Lorne A. Clarke, Yi Qian, and Allison R. Kermode
Validation of self-reported measures in health disparities research, Bertha Hidalgo and Melody Goodman
The impact of mild stroke on participation in physical fitness activities, Mary Hildebrand, Megan Brewer, and Timothy Wolf
Lysosomal membrane permeabilization is an early event in sigma-2 receptor ligand mediated cell death in pancreatic cancer, John R. Hornick, Suwanna Vangveravong, Dirk Spitzer, Carmen Abate, Francesco Berardi, Peter Goedegebuure, Robert H. Mach, and William G. Hawkins
Lecture: New light on the role of claudins in the kidney, Jianghui Hou
Expression of the transient receptor potential channels TRPV1, TRPA1 and TRPM8 in mouse trigeminal primary afferent neurons innervating the dura, Dongyue Huang, Shuyang Li, Ajay Dhaka, Gina M. Story, and Yu-Qing Cao
Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni, Stanley Ching-Cheng Huang, Tori C. Freitas, Eyal Amiel, Bart Everts, Erika L. Pearce, James B. Lok, and Edward J. Pearce
Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal, Sung-Ho Huh, Jennifer Jones, Mark E. Warchol, and David M. Ornitz
Clinical application of heart rate variability after acute myocardial infarction, Heikki V. Huikuri and Phyllis K. Stein
Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis, Michelle A. Hurchla and Katherine N. Weilbaecher
A core human microbiome as viewed through 16S rRNA sequence clusters, Susan M. Huse, Yuzhen Ye, Yanjiao Zhou, and Anthony A. Fodor
Differential replication of pathogenic and nonpathogenic strains of West Nile virus within astrocytes, Katherine L. Hussmann, Melanie A. Samuel, Kwang S. Kim, Michael S. Diamond, and Brenda L. Fredericksen
Adjuvant chemotherapy for breast cancer in patients with schizophrenia, Mark Hwang, Mishel Farasatpour, Campbell D. Williams, Julie A. Margenthaler, Katherine S. Virgo, and Frank E. Johnson
The mode of retinal presynaptic inhibition switches with light intensity, Tomomi Ichinose and Peter D. Lukasiewicz
Fast, sensitive discovery of conserved genome-wide motifs, NNamdi E. Ihuegbu, Gary D. Stormo, and Jeremy Buhler
Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system, Jamie M. Ireland and Emil R. Unanue
c-Src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton, Takashi Izawa, Wei Zou, Jean C. Chappel, Jason W. Ashley, Xu Feng, and Steven L. Teitelbaum
A survey tool for measuring evidence-based decision making capacity in public health agencies, Julie A. Jacobs, Paula F. Clayton, Cassandra Dove, Tanya Funchess, Ellen Jones, Ghazala Perveen, Brandon Skidmore, Victor Sutton, Sarah Worthington, Elizabeth A. Baker, Anjali D. Deshpande, and Ross C. Brownson
Tools for implementing an evidence-based approach in public health practice, Julie A. Jacobs, Ellen Jones, Barbara A. Gabella, Bonnie Spring, and Ross C. Brownson
GSK-3β: A bifunctional role in cell death pathways, Keith M. Jacobs, Sandeep R. Bhave, Daniel J. Ferraro, Jerry J. Jaboin, Dennis E. Hallahan, and Dinesh Thotala
Administration of COG1410 reduces axonal amyloid precursor protein immunoreactivity and microglial activation after controlled cortical impact in mice, Yong Jiang and David L. Brody
Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer’s disease Ibero-American cohort, Sheng C. Jin, Pau Pastor, Breanna Cooper, Sebastian Cervantes, Bruno A. Benitez, Cristina Razquin, Alison Goate, Ibero-American Alzheimer Disease Genetics Group Researchers, and Carlos Cruchaga
Antegrade endoscopic removal of retained urethral sling mesh in the bladder, Michael H. Johnson, Genoa G. Ferguson, and Carl G. Klutke
It's all in the lens: Differences in views on obesity prevention between advocates and policy makers, Ellen Jones, Amy A. Eyler, Leah Nguyen, Jooyoung Kong, Ross C. Brownson, and Jessica H. Bailey
Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy, Pierre-Emmanuel Joubert, Scott Werneke, Claire de la Calle, Florence Guivel-Benhassine, Alessandra Giodini, Lucie Peduto, Beth Levine, Olivier Schwartz, Deborah Lenschow, and Matthew L. Albert
Chikungunya virus-induced autophagy delays caspase-dependent cell death, Pierre-Emmanuel Joubert, Scott W. Werneke, Claire de la Calle, Florence Guivel-Benhassine, Alessandra Giodini, Lucie Peduto, Beth Levine, Olivier Schwartz, Deborah J. Lenschow, and Matthew L. Albert
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network, Kenneth K. Karanja, Stephanie W. Cox, Julien P. Duxin, Sheila A. Stewart, and Judith L. Campbell
Expression of novel Alzheimer’s disease risk genes in control and Alzheimer’s disease brains, Celeste M. Karch, Amanda T. Jeng, Petra Nowotny, Janet Cady, Carlos Cruchaga, and Alison M. Goate
Heart rate variability changes at 2400 m altitude predicts acute mountain sickness on further ascent at 3000–4300 m altitudes, Heikki M. Karinen, Arja Uusitalo, Henri Vaha-Ypya, Mika Kahonen, Juha E. Peltonen, Phyllis K. Stein, Jari Viik, and Heikki O. Tikkanen
A multicenter study of Clostridium difficile infection-related colectomy, 2000-2006, Amelia M. Kasper, Humaa A. Nyazee, Deborah S. Yokoe, Jeanmarie Mayer, Julie E. Mangino, Yosef M. Khan, Bala Hota, Victoria J. Fraser, and Erik R. Dubberke
Pediatric glioma-associated KIAA1549:BRAF expression regulates neuroglial cell growth in a cell type-specific and mTOR-dependent manner, Aparna Kaul, Yi-Hsien Chen, Ryan J. Emnett, Sonika Dahiya, and David H. Gutmann
Differences in corneal phenotypes between destrin mutants are due to allelic difference and modified by genetic background, Sharon V. Kawakami-Schulz, Angela M. Verdoni, Shannon G. Sattler, Akihiro Ikeda, and Sakae Ikeda
Effect of inhaled glucocorticoids in childhood on adult height, H. William Kelly, Alice L. Sternberg, Rachel Lescher, Anne L. Fuhlbrigge, Paul Williams, Robert S. Zeiger, Hengameh H. Raissy, Mark L. Van Natta, James Tonascia, and Robert C. Strunk
Year in review 2011: Critical Care – neurocritical care, Salah G. Keyrouz and Michael N. Diringer
Ewing's sarcoma: A case report of a 52-year-old woman with recurrent tumor and literature review, Waseem Khaliq, Mohammad Farshad Bahador, Thomas Nichols Laurence, Ronald Andrew Sapiente, James Sheridan Lewis Jr., and David Lee Graham
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration, Shyam B. Khatau, Ryan J. Bloom, Saumendra Bajpai, David Razafsky, Shu Zhang, Anjil Giri, Pei-Hsun Wu, Jorge Marchand, Alfredo Celedon, Christopher M. Hale, Sean X. Sun, Didier Hodzic, and Denis Wirtz
Actin cap associated focal adhesions and their distinct role in cellular mechanosensing, Dong-Hwee Kim, Shyam B. Khatau, Yunfeng Feng, Sam Walcott, Sean X. Sun, Gregory D. Longmore, and Denis Wirtz
Off-clamp robot-assisted partial nephrectomy for complex renal tumors, Eric H. Kim, Youssef S. Tanagho, Gurdarshan Sandhu, Sam B. Bhayani, and R. Sherburne Figenshau
A noncomplementation screen for quantitative trait alleles in Saccharomyces cerevisiae, Hyun Seok Kim, Juyoung Huh, Linda Riles, Alejandro Reyes, and Justin C. Fay
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis, Jungsu Kim, Adam E M Eltorai, Hong Jiang, Fan Liao, Philip B. Verghese, Jaekwang Kim, Floy R. Stewart, Jacob M. Basak, and David M. Holtzman
Prefrontal and striatal activity related to values of objects and locations, Soyoun Kim, Xinying Cai, Jaewon Hwang, and Daeyeol Lee
A role for the membrane Golgi protein Ema in autophagy, Sungsu Kim and Aaron DiAntonio
Functional consequences of cell type-restricted expression of laminin alpha-5 in mouse placental labyrinth and kidney glomerular capillaries, Sung Tae Kim, Tracy L. Adair-Kirk, Robert M. Senior, and Jefrey H. Miner
Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli, Kimberly A. Kline, Drew J. Schwartz, Nicole M. Gilbert, Scott J. Hultgren, and Amanda L. Lewis
How do short-term changes at synapses fine-tune information processing?, Achim Klug, J. Gerard G. Borst, Bruce A. Carlson, Cornelia Kopp-Scheinpflug, Vitaly A. Klyachko, and Matthew A. Xu-Friedman
Isolated lymphoid follicles are dynamic reservoirs for the induction of intestinal IgA, Kathryn A. Knoop and Rodney D. Newberry
VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing, Daniel C. Koboldt, Qunyuan Zhang, David E. Larson, Dong Shen, Michael D. McLellan, Ling Lin, Christopher A. Miller, Elaine R. Mardis, Li Ding, and Richard K. Wilson
A randomized trial of 7-day doripenem versus 10-day imipenem-cilastatin for ventilatorassociated pneumonia, Marin H. Kollef, Jean Chastre, Marc Clavel, Marcos I. Restrepo, Bart Michiels, Kone Kaniga, Iolanda Cirillo, Holly Kimko, and Rebecca Redman
Economic impact of ventilator-associated pneumonia in a large matched cohort, Marin H. Kollef, Cindy W. Hamilton, and Frank R. Ernst
Ubiquitination and degradation of the hominoid- specific oncoprotein TBC1D3 Is mediated by CUL7 E3 ligase, Chen Kong, Dmitri Samovski, Priya Srikanth, Marisa J. Wainszelbaum, Audra J. Charron, Jialiu Liu, Jeffrey J. Lange, Pin-I Chen, Zhen-Qiang Pan, Xiong Su, and Philip D. Stahl
Revised sequence and annotation of the Rhodobacter sphaeroides 2.4.1 Genome, Wayne S. Kontur, Wendy S. Schackwitz, Natalia Ivanova, Joel Martin, Kurt LaButti, Shweta Deshpande, Hope N. Tice, Christa Pennacchio, Erica Sodergren, George M. Weinstock, Daniel R. Noguera, and Timothy J. Donohue
Distinguishing the contribution of type 1 pili from that of other QseB-misregulated factors when QseC is absent during urinary tract infection, Maria Kostakioti, Maria Hadjifrangiskou, Corinne K. Cusumano, Thomas J. Hannan, James W. Janetka, and Scott J. Hultgren
Challenging presentations of cavernous sinus thrombophlebitis, Courtney L. Kraus and Susan M. Culican
Small media and client reminders for colorectal cancer screening: Current use and gap areas in CDC's colorectal cancer control program, Matthew W. Kreuter, Lori B. Garibay, Debbie J. Pfeiffer, Jennifer C. Morgan, Melonie Thomas, Katherine M. Wilson, Jennifer Pieters, Kellie Szczepaniec, Amy Scott, and Timothy J. Poor
Polygenic threshold model with sex dimorphism in adolescent idiopathic scoliosis: The Carter effect, Lisa M. Kruse, Jillian G. Buchan, Christina A. Gurnett, and Matthew B. Dobbs
Rehabilitation after anterior cruciate ligament reconstruction: A systematic review, L. M. Kruse, B. Gray, and R. W. Wright
The L.E.A.D. framework: Using tools from evidence-based public health to address evidence needs for obesity prevention, Shiriki Kumanyika, Ross C. Brownson, and Allen Cheadle
Prospective multi-center study of oncologic outcomes of robot-assisted partial nephrectomy for pT1 renal cell carcinoma, Rachel L. Kyllo, Youssef S. Tanagho, Jihad H. Kaouk, Michael D. Stifelman, Craig G. Rogers, Shahab P. Hillyer, Shyam S. Sukumar, Kenneth G. Nepple, and Sam B. Bhayani
Observational Research in Childhood Infectious Diseases (ORChID): A dynamic birth cohort study, Stephen Bernard Lambert, Robert S. Ware, Anne L. Cook, Frances A. Maguire, David M. Whiley, Seweryn Bialasiewicz, Ian M. Mackay, David Wang, Theo P. Sloots, Michael D. Nissen, and Keith Grimwood
Paragonimus kellicotti Fluke infections in Missouri, USA, Michael A. Lane, Mary C. Barsanti, Carlos A. Santos, Michael Yeung, Sam J. Lubner, and Gary J. Weil
Beyond 30 days: Does limiting the duration of surgical site infection follow-up limit detection?, Julie D. Lankiewicz, Deborah S. Yokoe, Margaret A. Olsen, Fallon Onufrak, Victoria J. Fraser, Kurt Stevenson, Yosef Khan, David Hooper, Richard Platt, and Susan S. Huang
Multiscale forward electromagnetic model of uterine contractions during pregnancy, Patricio S. La Rosa, Hari Eswaran, Hubert Preissl, and Arye Nehorai
Ybcl of uropathogenic escherichia coli suppresses transepithelial neutrophil migration, Megan E. Lau, Jennifer A. Loughman, and David A. Hunstad
AHR and the transcriptional regulation of Type-17/22 ILC, Jacob S. Lee, Marina Cella, and Marco Colonna
Clustering of resting state networks, Megan H. Lee, Carl D. Hacker, Abraham Z. Snyder, Maurizio Corbetta, Dongyang Zhang, Eric C. Leuthardt, and Joshua S. Shimony
Natural killer cell regulation by microRNAs in health and disease, Jeffrey W. Leong, Ryan P. Sullivan, and Todd A. Fehniger
Temporal evolution of gamma activity in human cortex during an overt and covert word repetition task, Eric C. Leuthardt, Xiao-Mei Pei, Jonathan Breshears, Charles Gaona, Mohit Sharma, Zac Freudenberg, Dennis Barbour, and Gerwin Schalk
Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi, Ben-Wen Li, Zhengyuan Wang, Amy C. Rush, Makedonka Mitreva, and Gary J. Weil
The function and evolution of the restriction factor viperin in primates was not driven by lentiviruses, Efrem S. Lim, Lily I. Wu, Harmit S. Malik, and Michael Emerman
Political and social determinants of life expectancy in less developed countries: A longitudinal study, Ro-Ting Lin, Ya-Mei Chen, Lung-Chang Chien, and Chang-Chuan Chan
DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease, Xiangmin Lin, Travis J. Cook, Cyrus P. Zabetian, James B. Leverenz, Elaine R. Peskind, Shu-Ching Hu, Kevin C. Cain, Catherine Pan, John Scott Edgar, David R. Goodlett, Brad A. Racette, Harvey Checkoway, Thomas J. Montine, Min Shi, and Jing Zhang
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success, Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, and Alexander S. Krupnick
Compound heterozygous mutations in the SUR1 (ABCC 8) subunit of pancreatic KATP channels cause neonatal diabetes by perturbing the coupling between Kir6.2 and SUR1 subunits, Yu-Wen Lin, Alejandro Akrouh, YeouChing Hsu, Nkecha Hughes, Colin G. Nichols, and Diva D. De Leon
Correlations of coronary plaque wall thickness with wall pressure and wall pressure gradient: A representative case study, Biyue Liu, Jie Zheng, Richard Bach, and Dalin Tang
CHFR is important for the first wave of ubiquitination at DNA damage sites, Chao Liu, Jiaxue Wu, Sharad C. Paudyal, Zhongsheng You, and Xiaochun Yu
Intravital 2-photon imaging of leukocyte trafficking in beating heart, Wenjun Li, Ruben G. Nava, Alejandro C. Bribriesco, Bernd H. Zinselmeyer, Jessica H. Spahn, Andrew E. Gelman, Alexander S. Krupnick, Mark J. Miller, and Daniel Kreisel
The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel, Lipin Loo, Andrew J. Shepherd, Aaron D. Mickle, Ramon A. Lorca, Leonid P. Shutov, Yuriy M. Usachev, and Durga P. Mohapatra
Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbionts, Catherine Lozupone, Karoline Faust, Jeroen Raes, Jeremiah J. Faith, Daniel N. Frank, Jesse Zaneveld, Jeffrey I. Gordon, and Rob Knight
The association of neonatal dacryocystoceles and infantile dacryocystitis with nasolacrimal duct cysts (an American Ophthalmogical Society Thesis), Gregg T. Lueder
An Australian twin study of cannabis and other illicit drug use and misuse, and other psychopathology, Michael T. Lynskey, Arpana Agrawal, Anjali Henders, Elliot C. Nelson, Pamela A.F. Madden, and Nicholas G. Martin
Re-orientation of clinical research in traumatic brain injury: Report of an international workshop on comparative effectiveness research, Andrew I.R. Maas, David K. Menon, Hester F. Lingsma, Jose A. Pineda, M. Elizabeth Sandel, and Geoffery T. Manley
Splint: The efficacy of orthotic management in rest to prevent equinus in children with cerebral palsy, a randomised controlled trial, Josina C. Maas, Annet J. Dallmeijer, Peter A. Huijing, Janice E. Brunstrom-Hernandez, Petra J. van Kampen, Richard T. Jaspers, and Jules G. Becher
Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models, Cynthia X. Ma, Shirong Cai, Shunqiang Li, Christine E. Ryan, Zhangfang Guo, W. Timothy Schaiff, Li Lin, Jeremy Hoog, Reece J. Goiffon, Aleix Prat, Rebecca L. Aft, Matthew J. Ellis, and Helen Piwnica-Worms
Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion, P. A. F. Madden, A. C. Heath, and et al
Diazoxide maintains human myocyte volume homeostasis during stress, Sara K. Maffit, Angela D. Sellitto, Ashraf S. Al-Dadah, Richard B. Schuessler, Ralph J. Damiano Jr., and Jennifer S. Lawton
