The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2006

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Blocking monoclonal antibodies specific for mouse IFN-α/β receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection, Kathleen C F Sheehan, Koon Siew Lai, Gavin P. Dunn, Allen T. Bruce, Mark S. Diamond, Jennifer D. Heutel, Corazon Dungo-Arthur, Javier A. Carrero, J. Michael White, Paul J. Herzog, and Robert D. Schreiber

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A prospective study of differences in duodenum compared to remaining small bowel motion between radiation treatments: Implications for radiation dose escalation in carcinoma of the pancreas, Anurag K. Singh, Ryan M. Tierney, Daniel A. Low, Parag J. Parikh, Robert J. Myerson, Joseph O. Deasy, Catherine S. Wu, Gisele C. Pereira, Sasha H. Wahab, Sasa Mutic MS, Perry W. Grigsby, and Andrew J. Hope

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Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host, Justin L. Sonnenburg, Christina T. Chen, and Jeffery I. Gordon

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COG-7-deficient human fibroblasts exhibit altered recycling of Golgi proteins, Richard Steet and Stuart Kornfeld

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The role of myristoylation in the membrane association of the Lassa virus matrix protein Z, Thomas Strecker, Anna Maisa, Stephane Daffis, Robert Eichler, Oliver Lenz, and Wolfgang Garten

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The Haemophilus influenzae Type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence, Soila Sukupolvi-Petty, Susan Grass, and Joseph W. St. Geme III

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Choosing the best heuristic for seeded alignment of DNA sequences, Yanni Sun and Jeremy Buhler

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PKR-dependent autophagic degradation of herpes simplex virus type 1, Zsolt Talloczy, Herbert W. Virgin IV, and Beth Levine

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Cortactin has an essential and specific role in osteoclast actin assembly, Shandiz Tehrani, Roberta Faccio, Indra Chandrasekar, F. Patrick Ross, and John A. Cooper

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Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion, Joshua M. Thurman, Danica Ljubanovic, Pamela A. Royer, Damian M. Kraus, Hector Molina, Nicholas P. Barry, Gregory Proctor, Moshe Levi, and V. Michael Holers

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The alchemy of tendon repair: A primer for the (S)mad scientist, Dwight A. Towler and Richard H. Gelberman

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Endocytosis of cadherin from intracellular junctions is the driving force for cadherin adhesive dimer disassembly, Regina B. Troyanovsky, Eugene P. Sokolov, and Sergey M. Troyanovsky

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Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals, Jeffrey W. Tyner, Edy Y. Kim, Kyotaro Ide, Mark R. Pelletier, William T. Roswit, Jeffrey D. Morton, John T. Battaile, Anand C. Patel, G. Alexander Patterson, Mario Castro, Melanie S. Spoor, Yingjian You, Steven L. Brody, and Michael Holtzman

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Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes, Teun WJM van Herpen, Svetlana V. Goryunova, Johanna van der Schoot, Makedonka Mitreva, Elma Salentijn, Oscar Vorst, Martijn F. Schenk, Peter A. van Veelen, Frits Koning, Loek JM van Soest, Ben Vosman, Dirk Bosch, Rob J. Hamer, Luud JWJ Gilissen, and Marinus JM Smulders

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Validation of string test for diagnosis of Helicobacter pylon infections, Billie Velapatino, Jacqueline Balqui, Robert H. Gilman, Alejandro Bussalleu, Willi Quino, S. Alison Finger, Livia Santivanez, Phabiola Herrera, Alejandro Piscoya, Jose Valdiva, Jaime Cok, and Douglas E. Berg

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Identification of non-dot/icm suppressors of the Legionella pneumophila △dotL lethality phenotype, Carr D. Vincent, Benjamin A. Buscher, Jonathan R. Friedman, Lee Anne Williams, Patrick Bardill, and Joseph P. Vogel

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Genetic influences on free and cued recall in long-term memory tasks, Heather E. Volk, Kathleen B. McDermott, Henry L. Roediger III, and Richard D. Todd

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Las noticias de Madrid (News from Madrid), Suzanne Elizabeth Wahrle

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A steganalysis-based approach to comprehensive identification and characterization of functional regulatory elements, Guandong Wang and Weixiong Zhang

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Epimorphin-/- mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis, Yuan Wang, Lihua Wang, Hristo Iordanov, Elzbieta A. Sweitlicki, Qun Zheng, Shujun Jiang, Yuzhu Tang, Marc S. Levin, and Deborah C. Rubin

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A multicenter intervention to prevent catheter-associate bloodstream infections, David K. Warren, Sara E. Cosgrove, Daniel J. Diekema, Gianna Zuccotti, Michael W. Climo, Maureen K. Bolon, Jerome I. Tokars, Gary A. Noskin, Edward S. Wong, Kent A. Sepkowitz, Loreen A. Herwaldt, Trish M. Perl, Steven L. Solomon, and Victoria J. Fraser

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Epidemiology of methicillin-resistant Staphylococcus aureus colonization in a surgical intensive care unit, David K. Warren, Rebecca M. Guth, Craig M. Coopersmith, Liana R. Merz, Jeanne E. Zack, and Victoria J. Fraser

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Preventing catheter-associated bloodstream infections: A survey of policies for insertion and care of central venous catheters from hospitals in the prevention epicenter program, David K. Warren, Deborah S. Yokoe, Michael W. Climo, Loreen A. Herwaldt, Gary A. Noskin, Gianna Zuccotti, Jermone I. Tokars, Trish M. Perl, and Victoria J. Fraser

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A general coverage theory for shotgun DNA sequencing, Michael C. Wendl

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The demographic and morphological features of rotator cuff disease: A comparison of asymptomatic and symptomatic shoulders, Ken Yamaguchi, Konstantinos Ditsios, William D. Middleton, Charles F. Hildebolt, Leesa M. Galatz, and Sharlene A. Teefey

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Harpin mediates cell aggregation in Erwinia chrysanthemi 3937, Mee-Ngan Yap, Clemencia M. Rojas, Ching-Hong Yang, and Amy O. Charkowski

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A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis, Aki Yoneda and Tamara L. Doering

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Nucleophosmin is essential for ribosomal protein L5 nuclear export, Yue Yu, Leonard B. Maggi Jr., Suzanne N. Brady, Anthony J. Apicelli, Mu-Shui Dai, Hua Lu, and Jason D. Weber

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Slo3 K+ channels: Voltage and pH dependence of macroscopic currents, Xue Zhang, Xuhui Zeng, and Christopher J. Lingle

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pH-regulated Slo3 K+ channels: Properties of unitary currents, Xue Zhang, Xuhui Zeng, Xiao-Ming Xia, and Christopher J. Lingle

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The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins, Xuejun Zhong, Parie Garg, Stephanie A. Nick McElhinny, Carrie M. Stith, Grace E. Kissling, Peter M.J. Burgers, and Thomas A. Kunkel

Submissions from 2005

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CD36 may determine our desire for dietary fats, Nada A. Abumrad

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Low ambient O2 enhances ureteric bud branching in vitro, Tetsu Akimoto, Marc R. Hammerman, and Eiji Kusano

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Comparison of holding strength of suture anchors for hepatic and renal parenchyma, Caroline D. Ames, Juan M. Perrone, Alison J. Frisella, Kevin Morrissey, and Jaime Landman

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Preclinical and clinical performance of the Efoora test, a rapid test for detection of human immunodeficiency virus-specific antibodies, Max Q. Arens, Linda M. Mundy, and et al

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NF-κB-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis, Kunihiko Aya, Muhammad Alhawagri, Amanda Hagen-Stapleton, Hideki Kitaura, Osami Kanagawa, and Deborah Veis Novack

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Genetic Analysis Workshop 14: Microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans, Joan E. Bailey-Wilson, Laura Almasy, Mariza de Andrade, Julia Bailey, Heike Bickeböller, Heather J. Cordell, E Warwick Daw, Lynn Goldin, Ellen L. Goode, Courtney Gray-McGuire, Wayne Hening, Gail Jarvik, Brion S. Maher, Nancy Mendell, Andrew D. Paterson, John Rice, Glen Satten, Brian Suarez, Veronica Vieland, Marsha Wilcox, Heping Zhang, Andreas Ziegler, and Jean W. MacCluer

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FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner, Shuting Bai, Hideki Kitaura, Haibo Zhao, Ju Chen, Judith M. Muller, Roland Schule, Bryant Darnay, Deborah V. Novack, Patrick Ross, and Steven L. Teitelbaum

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Eukaryotic UDP-galactopyranose mutase (GLF Gene) in microbial and metazoal pathogens, Stephen M. Beverley, Katherine L. Owens, Melissa Showalter, Cara L. Griffith, Tamara L. Doering, Victoria C. Jones, and Michael R. McNeil

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Phenotypic and molecular analysis of tellurite resistance among enterohemorrhagic Escherichia coli O157:H7 and sorbitol-fermenting O157:NM clinical isolates, Martina Bielaszewska, Phillip I. Tarr, Helge Karch, Wenlan Zhang, and Werner Mathys

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Molecular profiling and phenotype analysis of Escherichia coli O26:H11 and O26:NM: Secular and geographic consistency of enterohemorrhagic and enteropathogenic isolates, Martina Bielaszewska, Wenlan Zhang, Phillip I. Tarr, Anne-Katharina Sonntag, and Helge Karch

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Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality, Valerie Blanc, Jeffrey O. Henderson, Elizabeth P. Newberry, Susan Kennedy, Jianyang Luo, and Nicholas O. Davidson

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The ethics and politics of stem cell research, James C. Bobrow

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An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism, Michael R. Bowl, Andrew Nesbit, Brian Harding, Elaine Levy, Andrew Jefferson, Emanuela Volpi, Karine Rizzoti, Robin Lovell-Badge, David Schlessinger, Michael P. Whyte, and Rajesh V. Thakker

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Objectives of undergraduate medical education in musculoskeletal surgery and medicine, Martin I. Boyer

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Anti-Aβ antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice, Robert P. Brendza, Brain J. Bacskai, John R. Cirrito, Kelly A. Simmons, Jesse M. Skoch, William E. Klunk, Chester A. Mathis, Kelly R. Bales, Steven M. Paul, Bradley T. Hyman, and David M. Holtzman

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What's new in spine surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, and Jeffrey C. Wang

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The DotL protein, a member of the TraG-coupling protein family, is essential for viability of Legionella pneumophila strain Lp02, Benjamin A. Buscher, Gloria M. Conover, Jennifer L. Miller, Sinae A. Vogel, Stacey N. Meyers, Ralph R. Isberg, and Joseph P. Vogel

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Replication protein A-directed unloading of PCNA by the Ctf18 cohesion establishment complex, Goran O. Bylund and Peter M. J. Burgers

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The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein, David A. Canton, Mary Ellen K. Olsten, Kyoungtae Kim, Amanda Doherty-Kirby, Gilles Lajoie, John A. Cooper, and David W. Litchfield

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Antioxidant supplementation for the prevention of kwashiorkor in Malawian children: Randomised, double blind, placebo controlled trial, Heather Ciliberto, Michael Ciliberto, Andree Briend, Per Ashorn, Dennis Bier, and Mark Manary

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P-glycoprotein deficiency at the blood-brain barrier increases amyloid-β deposition in an Alzheimer disease mouse model, John R. Cirrito, Rashid Deane, Anne M. Fagan, Michael L. Spinner, Maia Parsadanian, Mary Beth Finn, Hong Jiang, Julie L. Prior, Abhay Sagare, Kelly R. Bales, Steven M. Paul, Berislav V. Zlokovic, David Piwinca-Worms, and David M. Holtzman

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Periacetabular osteotomy for the treatment of severe acetabular dysplasia, John C. Clohisy, Susan E. Barrett, J. Eric Gordon, Eliana D. Delgado, and Perry L. Schoenecker

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Architecture and adhesive activity of the Haemophilus influenzae Hsf adhesin, Shane E. Cotter, Hye-Jeong Yeo, Twyla Juehne, and Joseph W. St. Geme III

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Identification of functional transcription factor binding sites using closely related Saccharomyces species, Scott W. Doniger, Juyoung Huh, and Justin C. Fay

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CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood, Victor A. Drover, Mohammad Ajmal, Fatiha Nassir, Nicholas O. Davidson, Andromeda M. Nauli, Daisy Sahoo, Patrick Tso, and Nada A. Abumrad

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Use of several inducer and substrate antibiotic combinations in a disk approximation assay format to screen for AmpC induction in patient isolates of Pseudomonas aeruginosa, Enterobacter spp., Citrobacter spp., and Serratia spp., W. Michael Dunne Jr. and Daniel J. Hardin

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Microsatellites versus single-nucleotide polymorphisms in linkage analysis for quantitative and qualitative measures, Gerald Dunn, Anthony L. Hinrichs, Sarah Bertelsen, Carol H. Jin, John SK Kauwe, Brian K. Suarez, and Laura J. Bierut

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A model of the statistical power of comparative genome sequence analysis, Sean R. Eddy

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‘‘Antedisciplinary’’ science, Sean R. Eddy

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Gene finding in the chicken genome, Eduardo Eyras, Alexandre Reymond, Robert Castelo, Jacqueline M. Bye, Francisco Camara, Paul Flicek, Elizabeth J. Huckle, Genis Parra, David D. Shteynberg, Carine Wyss, Jane Rogers, Stylianos E. Antonarakis, Ewan Birney, Roderic Guigo, and Michael R. Brent

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Effects of combined diethylcarbamazine and albendazole treatment of bancroftian filariasis on parasite uptake and development in Culex pipiens L., Hoda A. Farid; Ragaa E. Hammad; Marah M. Hassan; Reda M.R, Ramzy; Maged El Setouhy; and Gary J. Weil

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Evidence for domesticated and wild populations of saccharomyces cerevisiae, Justin C. Fay and Joseph A. Benavides

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The LIM protein Ajuba influences interleukin-1-induced NF-κB activation by affecting the assembly and activity of the protein kinase Cζ/p62/TRAF6 signaling complex, Yungfeng Feng and Gregory D. Longmore

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Dominant negative effects of the AML1/ETO fusion oncoprotein, Timothy S. Fenske, Gina Pengue, and Timothy A. Graubert

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Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases, Angela M. Ferguson, Lynn S. White, Peter J. Donovan, and Helen Piwnica-Worms

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Patterns and predictors of inpatient falls and fall-related injuries in a large academic hospital, Irene D. Fischer, Melissa J. Krauss, William Claiborne Dunagan, Stanley Birge, Eileen Hitcho, Shirley Johnson, Eileen Constantinou, and Victoria J. Fraser

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Pseudomonas aeruginosa acquires biofilm-like properties within airway epithelial cells, Raquel Garcia-Medina, W. Michael Dunne, Pradeep K. Singh, and Steven L. Brody

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How the cell deals with DNA nicks, Parie Garg and Peter M.J. Burgers

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Computational technique for improvement of the position-weight matrices for the DNA/protein binding sites, Naum I. Gershenzon, Gary D. Stormo, and Illya P. Ioshikhes

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Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics, Jason Gertz, Linda Riles, Peter Turnbaugh, Su-Wen Ho, and Barak A. Cohen

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Analysis of memory T lymphocyte activity following stimulation with overlapping HLA-A*2402, A*0101 and Cw*0402 restricted CMV pp65 peptides, Monica Ghei, David F. Stroncek, and Maurizio Provenzano

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Reporting quality of randomized trials in the diet and exercise literature for weight loss, Cheryl A. Gibson, Erik P. Kirk, James D. LeCheminant, Bruce W. Bailey Jr, Guoyuan Huang, and Joseph E. Donnelly

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The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression, Nathan A. Gillespie, John B. Whitfield, Ben Williams, Andrew C. Heath, and Nicholas G. Martin

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Upper-extremity phocomelia reexamined: A longitudinal dysplasia, Charles A. Goldfarb, Paul R. Manske, Riccardo Busa, Janith Mills, Peter Carter, and Marybeth Ezaki

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Comparative genome analysis reveals a conserved family of actin-like proteins in apicomplexan parasites, Jennifer L. Gordon and L David Sibley

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Comprehensive treatment of late-onset tibia vara, J. Eric Gordon, Fred P. Heidenreich, Chris J. Carpenter, Jill Kelly-Hahn, and Perry L. Schoenecker

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Adolescent alcohol use is a risk factor for adult alcohol and drug dependence: Evidence from a twin design, Julia D. Grant, Jeffrey F. Scherrer, Michael T. Lynskey, Michael J. Lyons, Seth A. Eisen, Ming T. Tsuang, William R. true, and Kathleen K. Bucholz

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Rfam: Annotating non-coding RNAs in complete genomes, Sam Griffiths-Jones, Simon Moxon, Mhairi Marshall, Ajay Khanna, Sean R. Eddy, and Alex Bateman

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The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells, Thomas E. Grys, Matthew B. Siegel, Wyndham W. Lathem, and Rodney A. Welch

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Involvement of human MOF in ATM function, Arun Gupta, Girdhar G. Sharma, Charles S. H. Young, Manjula Agarwal, Edwin R. Smith, Tanya T. Paull, John C. Lucchesi, Kum Kum Khanna, Thomas Ludwig, and Tej K. Pandita

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Paternal alcoholism and offspring conduct disorder: Evidence for the 'common genes' hypothesis, Jon R. Haber, Theodore Jacob, and Andrew C. Heath

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Yersinia enterocolitica invasin-dependent and invasin-independent mechanisms of systemic dissemination, Scott A. Handley, Rodney D. Newberry, and Virginia L. Miller

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Deep-etch EM reveals that the early poxvirus envelope is a single membrane bilayer stabilized by a geodetic "honeycomb" surface coat, John Heuser

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Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant, J. Hiemenz, P. Cagnoni, D. Simpson, S. Devine, N. Chao, J. Keirns, W. Lau, D. Facklam, and D. Buell

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Genomics in C. elegans: So many genes, such a little worm, LaDeana W. Hillier, Alan Coulson, John I. Murray, Zhirong Bao, John E. Sulston, and Robert H. Waterston

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Multipoint identity-by-descent computations for single-point polymorphism and microsatellite maps, Anthony L. Hinrichs, Sarah Bertelsen, Laura J. Bierut, Gerald Dunn, Carol H. Jin, John S. Kauwe, and Brian K. Suarez

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Microarray expression profiling identifies early signaling transcripts associated with 6-OHDA-induced dopaminergic cell death, William A. Holtz, Jay M. Turetzky, and Karen L. O'Malley

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Ultrasonic songs of male mice, Timothy E. Holy and Zhongsheng Guo

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Punctuated duplication seeding events during the evolution of human chromosome 2p11, Julie E. Horvath, Cassandra L. Gulden, Rhea U. Vallente, Marla Y. Eichler, Mario Ventura, John D. McPherson, Tina A. Graves, Richard K. Wilson, Stuart Schwartz, Mariano Rocchi, and Evan E. Eichler

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Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli, David A. Hunstad, Sheryl S. Justice, Chia S. Hung, Scott R. Lauer, and Scott J. Hultgren

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Mitochondrial energy metabolism in heart failure: A question of balance, Janice M. Huss and Daniel P. Kelly

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The type Iα inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane, Ivan Ivetac, Adam D. Munday, Marina V. Kisseleva, Xiang-Ming Zhang, Susan Luff, Tony Tiganis, James C. Whisstock, Tony Rowe, Phillip W. Majerus, and Christina A. Mitchell

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An improved internal mammary irradiation technique in radiation treatment of locally advanced breast cancers, Jian-Yue Jin, Eric E. Klein, Feng-Ming Kong, and Zuofeng Li

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The multiple biological roles of the 3’→5’ exonuclease of Saccharomyces cerevisiae DNA polymerase δ require switching between the polymerase and exonuclease domains, Yong Hawn Jin, Parie Garg, Carrie M. W. Stith, Hanan Al-Refai, Joan F. Sterling, Laura J. W. Murray, Thomas A. Kunkel, Michael A. Resnick, Peter M. Burgers, and Dmitry A. Gordenin

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Use of in vivo-induced antigen technology for identification of Escherichia coli O157:H7 proteins expressed during human infection, Manohar John, Indira T. Kudva, Robert W. Griffin, Allen W. Dodson, Bethany McManus, Bryan Krastins, David Sarracino, Ann Progulske-Fox, Jeffrey D. Hillman, Martin Handfield, Phillip I. Tarr, and Stephen B. Calderwood

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The IrgA homologue adhesin Iha is an Escherichia coli virulence factor in murine urinary tract infection, James R. Johnson, Srdjan Jelacic, Laura M. Schoening, Connie Clabots, Nurmohammad Shaikh, Harry L.T. Mobley, and Phillip I. Tarr

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Arthrodesis techniques in the management of stage-II and III acquired adult flatfoot deformity, Jeffrey E. Johnson and James R. Yu

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Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA Is required for pilus biogenesis in Escherichia coli, Sheryl S. Justice, David A. Hunstad, Jill Reiss Harper, Amy R. Duguay, Jerome S. Pinkner, James Bann, Carl Frieden, Thomas J. Silhavy, and Scott J. Hultgren

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An antagonist peptide mediates positive selection and CD4 lineage commitment of MHC class II–restricted T cells in the absence of CD4, Henry Kao and Paul M. Allen