The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2007

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Clostridium difficile in the intensive care unit: Epidemiology, costs, and colonization pressure, Steven J. Lawrence, Laura A. Puzniak, Brooke N. Shadel, Kathleen N. Gillespie, Marin H. Kollef, and Linda M. Mundy

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Comparative analysis of the regulation of rovA from the pathogenic Yersiniae, Matthew B. Lawrenz and Virginia L. Miller

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Evaluation of a novel chromogenic agar medium for isolation and differentiation of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis isolates, Nathan A. Ledeboer, Kingshuk Das, Michael Eveland, Celine Roger-Dalbert, Sandrine Mailler, Sonia Chatellier, and William Michael Dunne

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Prevalence of cervical spine stenosis: Anatomic study in cadavers, Michael J. Lee, Ezequiel H. Cassinelli, and K. Daniel Riew

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A little stress is good: IFN-γ, demyelination, and multiple sclerosis, Jason R. Lees and Anne H. Cross

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Adaptor function of PapF depends on donor strand exchange in P-pilus biogenesis of Escherichia coli, Yvonne M. Lee, Karen W. Dodson, and Scott J. Hultgren

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Management of juvenile idiopathic scoliosis, Lawrence G. Lenke and Matthew B. Dobbs

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Calmodulin kinase II inhibition enhances ischemic preconditioning by augmenting ATP-sensitive K+ current, Jingdong Li, Celine Marionneau, Olha Koval, Leonid Zingman, Peter J. Mohler, Jeanne M. Nerbonne, and Mark E. Anderson

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PTEN and phosphorylated AKT expression and prognosis in early- and late-stage non-small cell lung cancer, W. T. Lim, W. H. Zhang, C. R. Miller, J. W. Watters, F. Gao, A. Viswanathan, R Govindan, and H. L. McLeod

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Vascular injury from an arterial closure device, Jeffrey P. C. Lin, Brian G. Rubin, and William D. Middleton

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Large-scale in silico mapping of complex quantitative traits in inbred mice, Pengyuan Liu, Haris Vikis, Yan Lu, Daolong Wang, and Ming You

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Functional association of Sun1 with nuclear pore complexes, Qian Liu, Nelly Pante, Tom Misteli, Mohamed Elsagga, Melissa Crisp, Didier Hodzic, Brian Burke, and Kyle J. Roux

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Acrochordon-like basal cell carcinomas in patients with basal cell nevus syndrome, David N. Lortscher, Roberta D. Sengelmann, and Shawn B. Allen

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Contribution of invariant residues to the function of Rgg family transcription regulators, Jennifer Loughman and Michael G. Caparon

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Diffusion tensor imaging predicts hyperacute spinal cord injury severity, David N. Loy, Joong Hee Kim, Mingqiang Xie, Robert E. Schmidt, Kathryn Trinkaus, and Sheng-Kwei Song

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Psychotropic prescriptions in a sample including both healthy and mood and disruptive disordered preschoolers: relationships to diagnosis, impairment, prescriber type, and assessment methods, Joan L. Luby, Melissa Meade Stalets, and Andy C. Belden

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Three clinical cases of DSM-IV mania symptoms in preschoolers, Joan Luby, Mini Tandon, and Ginger Nicol

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Ivermectin resistance in Onchocerca volvulus: Toward a genetic basis, Sara Lustigman and James P. McCarter

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Common human cancer genes discovered by integrated gene-expression analysis, Yan Lu, Yijun Yi, Pengyuan Liu, Weidong Wen, Michael James, Daolong Wang, and Ming You

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Psychometric properties of DSM assessments of illicit drug abuse and dependence: Results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), M. T. Lynskey and A. Agrawal

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Mutations in α-tubulin confer dinitroaniline resistance at a cost to microtubule function, Christopher Ma, Catherine Li, Lakshmi Ganesan, Jean Oak, Susan Tsai, David Sept, and Naomi S. Morrissette

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Clamping the Mec1/ATR checkpoint kinase into action, Jerzy Majka and Peter M.J. Burgers

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Case-control study of surgical site infections associated with pacemakers and implantable cardioverter-defibrillators, Jonas Marschall, Diane Hopkins-Broyles, Marilyn Jones, Victoria J. Fraser, and David K. Warren

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Catheter-associated bloodstream infections in general medical patients outside the intensive care unit: A surveillance study, Jonas Marschall, Carole Leone, Marilyn Jones, Deborah Nihill, Victoria J. Fraser, and David K. Warren

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Regulation of KATP channel expression and activity by the SUR1 Nucleotide Binding Fold 1, Ricard Masia, George Caputa, and Colin G. Nichols

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Nectin-like proteins mediate axon-Schwann cell interactions along the internode and are essential for myelination, Patrice Maurel, Steven Einheber, Jolanta Galinska, Pratik Thaker, Isabel Lam, Marina B. Rubin, Steven S. Scherer, Yoshinuri Murakami, David H. Gutmann, and James L. Salzer

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Preparation of antidepressants for use in preclinical research, Jonathan E. McConathy, Catherine Capello, Nachwa Jarkas, Zachary N. Stowe, and Michael J. Owens

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Whole-mount techniques to evaluate subepithelial cellular populations in the adult mouse intestine, Keely G. McDonald and Rodney D. Newberry

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Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4, Michael D. McLellan, Yumi Kasai, Tracie L. Milner, Ginger A. Fewell, Lucinda L. Fulton, Elaine R. Mardis, Richard K. Wilson, and et al.

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PI3K(p110α) inhibitors as anti-cancer agents: Minding the heart, Julie R. McMullen and Patrick Y. Jay

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Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model, Samuel G. Melendez-Lopez, Scott Herdman, Ken Hirata, Min-Ho Choi, Youngchool Choe, Charles Craik, Conor R. Caffrey, Elisabeth Hansell, Jianhua Guo, Samuel L. Stanley Jr., Bibiana Chavez-Munguia, Yen Ting Chen, William R. Roush, James McKerrow, and et al.

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Health care-associated pneumonia and community-acquired pneumonia: A single-center experience, Scott T. Micek, Katherine E. Kollef, Richard M. Reichley, Nareg Roubinian, and Marin H. Kollef

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Addition of vasopressin to norepinephrine as independent predictor of mortality in patients with refractory septic shock: An observational study, Scott T. Micek, Poorvi Shah, James M. Hollands, Rina A. Shah, William D. Shannon, and Marin H. Kollef

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Exploring the inter-relationship of smoking age-at-onset, cigarette consumption and smoking persistence: Genes or environment?, Katherine I. Morley, Michael T. Lynskey, Pamela A F Madden, Susan A. Treloar, Andrew C. Heath, and Nicholas G. Martin

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Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model, John D. Morrey, Venkatraman Siddharthan, Aaron L. Olsen, Hong Wang, Justin G. Julander, Jeffery O. Hall, Hua Li, Jeffrey L. Nordstrom, Scott Koenig, Syd Johnson, and Michael S. Diamond

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Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease, Odity Mukherjee, John SK Kauwe, Kevin Mayo, John C. Morris, and Alison M. Goate

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Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii, Kisaburo Nagamune, Wandy L. Beatty, and L. David Sibley

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Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis, Kisaburo Nagamune, Silvia N.J. Moreno, and L. David Sibley

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MultiCode-PLx system for multiplexed detection of seventeen respiratory viruses, Frederick S. Nolte, David J. Marshall, Christopher Rasberry, Sabina Schievelbein, Grier G. Banks, Gregory A. Storch, Max Q. Arens, Richard S. Buller, and James R. Prudent

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Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells, Alex S. Nord, Karen Vranizan, Whittemore Tingley, Alexander C. Zambon, Kristina Hanspers, Loren G. Fong, Yan Hu, Peter Bacchetti, Thomas E. Ferrin, Patricia C. Babbitt, Scott W. Doniger, William C. Skarnes, Stephen G. Young, and Bruce R. Conklin

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Rapid maturation of effector T cells in tumors, but not lymphoid organs, during tumor regression, Lyse A. Norian and Paul M. Allen

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Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment, Carol S. North, Barry A. Hong, and David H. Alpers

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Phylogenetic diversity and microsphere array-based genotyping of human pathogenic fusaria, including isolates from the multistate contact lens-associated U.S. keratitis outbreaks of 2005 and 2006, Kerry O'Donnell, Brice A. Sarver, Mary Brandt, Douglas C. Chang, Judith Noble-Wang, Benjamin J. Park, Deanna A. Sutton, Lynette Benjamin, Mark Lindsley, Arvind Padhye, David M. Geiser, and Todd J. Ward

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Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks, Olanrewaju Okusanya, Alan Forrest, Robin DiFrancesco, Sanela Bilic, Susan Rosenkranz, Michael F. Para, Elizabeth Adams, Kevin E. Yarasheski, Richard C. Reichman, Gene D. Morse, and ACTG 5043 Protocol Team

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Shigella flexneri phagosomal escape is independent of invasion, Susanne Paetzold, Sebastian Lourido, Barbel Raupach, and Arturo Zychlinsky

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MAGED2: A novel p53-dissociator, Chris Papageorgio, Rainer Brachmann, Jue Zeng, Robert Culverhouse, Wanghai Zhang, and Howard McLeod

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The association of the activation-inducible tumor necrosis factor receptor and ligand with lumbar disc hermiation, Moon-Soo Park, Hwan-Mo Lee, Soo-Bong Hahn, Seong-Hwan Moon, Yung-Tae Kim, Choon-Sung Lee, Hyo-Won Jung, Byoung-Se Kwon, and K. Daniel Riew

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Site-1 protease is essential for endochondral bone formation in mice, Debabrata Patra, Xiaoyun Xing, Sherri Davies, Jennifer Bryan, Carl Franz, Ernst B. Hunziker, and Linda J. Sandell

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Toward an understanding of risk factors for anorexia nervosa: A case-control study, K. M. Pike, A. Hilbert, D. E. Wilfley, C. G. Fairburn, F. A. Dohm, B. T. Walsh, and R. Striegel-Moore

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Clinical significance of αII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury, Jose A. Pineda, Stephen B. Lewis, Alex B. Valadka, Linda Papa, H. Julia Hannay, Shelley C. Heaton, Jason A. Demery, Ming Cheng Liu, Jada M. Aikman, Veronica Akle, Gretchen M. Brophy, Joseph J. Tepas III, Kevin K. W. Wang, Claudia S. Robertson, and Ronald L. Hayes

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Genetic and environmental factors affecting self-esteem from age 14 to 17: A longitudinal study of Finnish twins, Anu Raevuori, Danielle M. Dick, Anna Keski-Rahkonen, Lea Pulkkinen, Richard J. Rose, Aila Rissanen, Jaakko Kaprio, Richard J. Viken, and Karri Silventoinen

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Intracellular mediators of transforming growth factor β superfamily signaling localize to endosomes in chicken embryo and mouse lenses in vivo, Ramya Rajagopal, Shunsuke Ishii, and David C. Beebe

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Polony analysis of gene expression in ES cells and blastocysts, C. Rieger, R. Poppino, R. Sheridan, K. Moley, R. Mitra, and D. Gottlieb

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Molecular refinement of gibbon genome rearrangements, Roberta Roberto, Oronzo Capozzi, Richard K. Wilson, Elaine R. Mardis, Mariana Lomiento, Eray Tuzun, Ze Cheng, Alan R. Mootnick, Nicoletta Archidiacono, Mariano Rocchi, and Evan E. Eichler

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Oxytocin in the circadian timing of birth, Jeffrey Roizen, Christina E. Luedke, Erik D. Herzog, and Louis J. Muglia

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Anionic lipids enriched at the ExPortal of Streptococcus pyogenes, Jason W. Rosch, Fong Fu Hsu, and Michael G. Caparon

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Detection of intracellular bacterial communities in human urinary tract infection, David A. Rosen, Thomas M. Hooton, Walter E. Stamm, Peter A. Humphrey, and Scott J. Hultgren

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Antiretroviral drug levels and interactions affect lipid, lipoprotein, and glucose metabolism in HIV-1 seronegative subjects: A pharmacokinetic- pharmacodynamic analysis, Susan Rosenkranz, Kevin E. Yarasheski, Michael F. Para, Richard C. Reichman, and Gene D. Morse

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Identification and characterization of small molecules that inhibit intracellular toxin transport, Jose B. Saenz, Teresa A. Doggett, and David B. Haslam

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Conduct disorder among Asians and Native Hawaiian/Pacific Islanders in the USA, J. T. Sakai, N. K. Risk, C. A. Tanaka, and R. K. Price

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GenMAPP 2: New features and resources for pathway analysis, Nathan Salomonis, Kristina Hanspers, Alexander C. Zambon, Karen Vranizan, Steven C. Lawlor, Kam D. Dahlquist, Scott W. Doniger, Josh Stuart, Bruce R. Conklin, and Alexander R. Pico

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Fine mapping of mouse QTLs for fatness using SNP data, Armin O. Schmitt, Hadi Al-Hasani, James M. Cheverud, Daniel Pomp, Lutz Bünger, and Gudrun A. Brockmann

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Increasing incidence of sterile-site infections due to non-multidrug- resistant, oxacillin-resistant Staphylococcus aureus among hospitalized patients, Garrett E. Schramm, Jennifer A. Johnson, Joshua A. Doherty, Scott T. Micek, and Marin H. Kollef

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Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: A before-after trial, Douglas J E Schuerer, Ingrid B. Borecki, David K. Warren, Victoria J. Fraser, John E. Mazuski, Walter A. Boyle, Timothy G. Buchman, Craig M. Coppersmith, and et al

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X-linked idiopathic infantile nystagmus associated with a missense mutation in FRMD7, Alan Shiels, Thomas M. Bennett, Jessica B. Prince, and Lawrence Tychsen

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DLGH1 is a negative regulator of T-lymphocyte proliferation, Linda M. Stephenson, Benedicte Sammut, Daniel B. Graham, Joaquim Chan-Wang, Karry L. Brim, Alan S. Huett, Ana V. Miletic, Tracie Kloeppel, Aimee Landry, Ramnik Xavier, and Wojciech Swat

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Correlates of stimulus-response congruence in the posterior parietal cortex, Gijsbert Stoet and Lawrence H. Snyder

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A novel mutation of the Keratin 12 gene responsible for a severe phenotype of Meesmann’s corneal dystrophy, Lori S. Sullivan, Eric B. Baylin, Ramon Font, Stephen P. Daiger, Jay S. Pepose, Thomas E. Clinch, Hisashi Nakamura, Xinping C. Zhao, and Richard W. Yee

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Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice, Jiusong Sun, Galina K. Sukhova, Min Yang, Paul J. Wolters, Lindsey A. MacFarlane, Peter Libby, Chingxiu Sun, Yadong Zhang, Jian Liu, Terri L. Ennis, Rebecca Knispel, Wanfen Xiong, Robert W. Thompson, B. Timothy Baxter, and Guo-Ping Shi

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Emblica officinalis and its enriched tannoids delay streptozotocin-induced diabetic cataract in rats, P. Suryanarayana, Megha Saraswat, J. Mark Petrash, and G. Bhanuprakash Reddy

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Prion protein repeat expansion results in increased aggregation and reveals phenotypic variability, Elizabeth M. H. Tank, David A. Harris, Amar A. Desai, and Heather L. true

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A tale of two templates: Automatically resolving double traces has many applications, including efficient PCR-based elucidation of alternative splices, Aaron E. Tenney, Jia Qian Wu, Laura Langton, Paul Klueh, Ralph Quatrano, and Michael R. Brent

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The neuroendocrine impact of chronic stress on cancer, Premal H. Thaker, Susan K. Lutgendorf, and Anil K. Sood

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Apigenin prevents UVB-induced cyclooxygenase 2 expression: Coupled mRNA stabilization and translational inhibition, Xin Tong, Rukiyah T. Van Dross, Adnan Abu-Yousif, Aubrey R. Morrison, and Jill C. Pelling

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Vascular biology and bone formation: Hints from HIF, Dwight A. Towler

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Stable and unstable cadherin dimers: mechanisms of formation and roles in cell adhesion, Regina B. Troyanovsky, Oscar Laur, and Sergey M. Troyanovsky

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Causing and curing infantile esotropia in primates: The role of decorrelated binocular input (an American Ophthalmological Society thesis), Lawrence Tychsen

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Identification and expression of Hop, an atypical homeobox gene expressed late in lens fiber cell terminal differentiation, Oleg Vasiliev, Simon J. Rhodes, and David C. Beebe

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Metastatic disease to the breast: the Washington University experience, Aislinn Vaughan, Jill R. Dietz, Jeffrey F. Moley, Mary K. DeBenedetti, Rebecca L. Aft, William E. Gillanders, Timothy J. Eberlein, Jon Ritter, and Julie A. Margenthaler

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Prospective randomized comparison of cutting and dilating disposable trocars for access during laparoscopic renal surgery, Ramakrishna Venkatesh, Chandru P. Sundaram, Robert S. Figenshau, Yan Yan, Gerald L. Andriole, Ralph V. Clayman, and Jaime Landman

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The RUNX2 transcription factor cooperates with the YES-associated protein, YAP65, to promote cell transformation, Michele I. Vitolo, Ian E. Anglin, William M. Mahoney Jr., Keli J. Renoud, Ronald B. Gartenhaus, Kurtis E. Bachman, and Antonino Passaniti

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Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms, Suzanne E. Wahrle, Aarti R. Shah, Anne M. Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J. Thal, Alison M. Goate, and David M. Holtzman

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Age at first sexual intercourse and teenage pregnancy in Australian female twins, Mary Waldron, Andrew C. Heath, Eric Turkheimer, Robert Emery, Kathleen K. Bucholz, Pamela A.F. Madden, and Nicholas G. Martin

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Calling cards for DNA-binding proteins, Haoyi Wang, Mark Johnston, and Robi David Mitra

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Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3, Xiaoli Wang, Roger A. Herr, Wei-Jen Chua, Lonnie Lybarger, Emmanuel J.H.J. Wiertz, and Ted H. Hansen

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Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway, XiaoZhe Wang, Richard D. Kennedy, Kallol Ray, Patricia Stuckert, Tom Ellenberger, and Alan D. D'Andrea

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ABIN-3: A molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions, Brian K. Weaver, Erwin Bohn, Barbi A. Judd, M. Pilar Gil, and Robert D. Schreiber

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Analysis of surgical smoke produced by various energy-based instruments and effect on laparoscopic visibility, Kyle J. Weld, Stephen Dryer, Caroline D. Ames, Kuk Cho, Chris Hogan, Myonghwa Lee, Pratim Biswas, and Jaime Landman

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Algebraic correction methods for computational assessment of clone overlaps in DNA fingerprint mapping, Michael C. Wendl

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Screen for genetic modifiers of stbm reveals that photoreceptor fate and rotation can be genetically uncoupled in the Drosophila eye, Tanya Wolff, Jake B. Guinto, and Amy S. Rawls

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Symposium integrating evidence-based medicine into clinical practice, Rick W. Wright, John E. Kuhn, Annunziato Amendola, Morgan H. Jones, and Kurt P. Spindler

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DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth, Chunlai Wu, Richard W. Daniels, and Aaron DiAntonio

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Inflammatory arthritis can be reined in by CpG-induced DC–NK cell cross talk, Hsin-Jung Wu, Heloisa Sawaya, Bryce Binstadt, Margot Brickelmaier, Amanda Blasius, Leonid Gorelik, Umar Mahmood, Ralph Weissleder, John Carulli, Christophe Benoist, and Diane Mathis

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An investigation of the effects of lipid-lowering medications: Genome-wide linkage analysis of lipids in the HyperGEN study, Jun Wu, Michael A. Province, Hilary Coon, Steven C. Hunt, John H. Eckfeldt, Donna K. Arnett, Gerardo Heiss, Cora E. Lewis, R Curtis Ellison, Dabeeru C. Rao, Treva Rice, and Aldi T. Kraja

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Neoplasia driven by mutant c-KIT Is mediated by intracellular, not plasma membrane, receptor signaling, Zhifu Xiang, Frederike Kreisel, Jennifer Cain, AnnaLynn Colson, and Michael H. Tomasson

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Genetic and environmental contributions to pathological gambling symptoms in a 10-year follow-up, Hong Xian, Jeffrey F. Scherrer, Wendy S. Slutske, Kamini R. Shah, Rachel Volberg, and Seth A. Eisen

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Evolution of symbiotic bacteria in the distal human intestine, Jian Xu, Michael A. Mahowald, Ruth E. Lay, Catherine A. Lozupone, Micah Hamady, Eric C. Martens, Bernard Henrissat, Pedro M. Coutinho, Patrick Minx, Philippe Latreille, Holland Cordum, Andrew Van Brunt, Kyung Kim, Robert S. Fulton, Lucinda A. Fulton, Sandra W. Clifton, Richard K. Wilson, Robin D. Knight, and Jeffrey I. Gordon

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LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival, Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Osami Kanagawa, Alec M. Cheng, Bernard Malissen, and Takashi Saito

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Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish, Chao-Tsung Yang, Anna E. Hindes, Keith A. Hultman, and Stephen L. Johnson

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Shotgun lipidomics identifies a paired rule for the presence of isomeric ether phospholipid molecular species, Kui Yang, Zhongdan Zhao, Richard W. Gross, and Xianlin Han