The Open Access Publications collection contains peer-reviewed articles authored by Washington University School of Medicine faculty that have been published in open access journals or authorized by the publishers for open access availability. Open access works are generally defined as being publicly available online and free of most licensing and copyright restrictions. The Bernard Becker Medical Library maintains this collection in support of Washington University’s commitment to the principles of open access publishing and making the scholarly work and research results of our faculty as widely and easily available as possible.

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Submissions from 2010

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Fasting and differential chemotherapy protection in patients, Lizzia Raffaghello, Fernando Safdie, Giovanna Bianchi, Tanya Dorff, Luigi Fontana, and Valter D. Longo

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Preventing preterm birth: the past limitations and new potential of animal models, Christine K. Ratajczak, Justin C. Fay, and Louis J. Muglia

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The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice, Daniel A. Rauch, Michelle A. Hurchla, John C. Harding, Hongju Deng, Lauren K. Shea, Mark C. Eagleton, Stefan Niewiesk, Michael D. Lairmore, David Piwnica-Worms, Thomas J. Rosol, Jason D. Weber, Lee Ratner, and Katherine N. Weilbaecher

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Analysis of Alzheimer’s disease severity across brain regions by topological analysis of gene co-expression networks, Monika Ray and Weixiong Zhang

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Quantitative biometric phenotype analysis in mouse lenses, Matthew A. Reilly and Usha P. Andley

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Economic burden of ventilator-associated pneumonia based on total resource utilization, Marcos I. Restrepo, Antonio Anzueto, Alejandro C. Arroliga, Bekele Afessa, Mark J. Atkinson, Ngoc J. Ho, Regina Schinner, Ronald L. Bracken, and Marin H. Kollef

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Variation in Streptococcus pyogenes NAD+ glycohydrolase is associated with tissue tropism, David J. Riddle, Debra E. Bessen, and Michael G. Caparon

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Effect of alternative temozolomide schedules on glioblastoma O 6-methylguanine-DNA methyltransferase activity and survival, Clifford G. Robinson, Juan M. Palomo, Gazanfar Rahmathulla, Mary V. McGraw, Jon R. Donze, Lili Liu, and Michael A. Vogelbaum

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Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rβ1 isoform that enhances DC migration, Richard T. Robinson, Shabaana A. Khader, Cynthia A. Martino, Jeffrey J. Fountain, Maria Teixeira-Coelho, John E. Pearl, Stephen T. Smiley, Gary M. Winslow, David L. Woodland, Michael J. Walter, Jose R. Conejo-Garcia, Ueli Gubler, and Andrea M. Cooper

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ENCODE whole-genome data in the UCSC Genome Browser, Kate R. Rosenbloom, Ting Wang, and et al

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shRNA-mediated decreases in c-Met levels affect the differentiation potential of human mesenchymal stem cells and reduce their capacity for tissue repair, Ivana Rosová, Daniel Link, and Jan A. Nolta

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A general co-expression network-based approach to gene expression analysis: comparison and applications, Jianhua Ruan, Angela K. Dean, and Weixiong Zhang

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Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD, Nancy L. Saccone, Robert C. Culverhouse, Tae-Hwi Schwantes-An, Lingwei Sun, Andrew C. Heath, Michele L. Pergadia, John P. Rice, Jen C. Wang, Pamela A.F Madden, Laura J. Bierut, and et al.

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SPOT: A web-based tool for using biological databases to prioritize SNPs after a genome-wide association study, Scott F. Saccone, Raphael Bolze, Prasanth Thomas, Jiaxi Quan, Gaurang Mehta, Ewa Deelman, Jay A. Tischfield, and John P. Rice

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Gallbladder infarction and liver abscess formation following right hepatic artery chemoembolization for metastatic neuroendocrine tumor, Christopher Sampson and Ryan Petersen

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Beyond citation analysis: a model for assessment of research impact, Cathy C. Sarli, Ellen K. Dubinsky, and Kristi L. Holmes

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Common genetic and environmental contributions to post-traumatic stress disorder and alcohol dependence in young women, C. E. Sartor, V. V. McCutcheon, N. E. Pommer, E. C. Nelson, J. D. Grant, A. E. Duncan, M. Waldron, K. K. Bucholz, P. A F Madden, and A. C. Heath

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SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus, Akiko Satoh, Cynthia S. Brace, Gal Ben-Josef, Tim West, David F. Wozniak, David M. Holtzman, Erik D. Herzog, and Shin-ichiro Imai

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More than Tuskegee: Understanding mistrust about research participation, Darcell P. Scharff, Katherine J. Mathews, Pamela Jackson, Jonathan Hoffsuemmer, Emeobong Martin, and Dorothy Edwards

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Effects of moderate-volume, high-load lower-body resistance training on strength and function in persons with Parkinson's disease: A pilot study, Brian K. Schilling, Ronald F. Pfeiffer, Mark S. LeDoux, Robyn E. Karlage, Richard J. Bloomer, and Michael J. Falvo

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Surface properties of Helicobacter pylori urease complex are essential for persistence, Tobias D. Schoep, Alma Fulurija, Fayth Good, Wei Lu, Robyn P. Himbeck, Carola Schwan, Sung Sook Choi, Douglas E. Berg, Peer R.E. Mittl, Mohammed Benghezal, and Barry J. Marshall

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Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia, Gustav Schonfeld, Pin Yue, and et al

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Neighborhood conditions, diabetes, and risk of lower-body functional limitations among middle-aged African Americans: A cohort study, Mario Schootman, Elena M. Andresen, Fredric D. Wolinsky, J Philip Miller, Yan Yan, and Douglas K. Miller

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Attention to memory and the environment: functional specialization and dynamic competition in human posterior parietal cortex, Carlo Sestieri, Gordon L. Shulman, and Maurizio Corbetta

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Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans, Scott Severance, Abbhirami Rajagopal, Anita U. Rao, Gustavo C. Cerqueira, Makedonka Mitreva, Najib M. El-Sayed, Michael Krause, and Iqbal Hamza

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Symptoms of psychological distress among African Americans seeking HIV-related mental health care, Enbal Shacham, Tania B. Basta, and Michael Reece

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The interplay of sociodemographic factors on virologic suppression among a U.S. outpatient HIV clinic population, Enbal Shacham, Diana Nurutdinova, Nur Onen, Katelin Stamm, and E. Turner Overton

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Characteristics of psychosocial support seeking during HIV-related treatment in western Kenya, Enbal Shacham, Michael Reece, Willis Owino Ong'or, Otieno Omollo, Patrick O. Monahan, and Claris Ojwang

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Epimorphin deletion protects mice from inflammation-induced colon carcinogenesis and alters stem cell niche myofibroblast secretion, Anisa Shaker, Elzbieta A. Swietlicki, Lihua Wang, Shujun Jiang, Birce Onal, Shashi Bala, Katherine DeSchryver, Rodney Newberry, Marc S. Levin, and Deborah C. Rubin

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MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair, Girdhar G. Sharma, Sairei So, Arun Gupta, Rakesh Kumar, Christelle Cayrou, Nikita Avvakumov, Utpal Bhadra, Raj K. Pandita, Matthew H. Porteus, David J. Chen, Jacques Cote, and Tej K. Pandita

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No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice, Haiyan Shen, Jonathan I. Matsui, Debin Lei, Lirong Han, Kevin K. Ohlemiller, and Jianxin Bao

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A SNP discovery method to assess variant allele probability from next-generation resequencing data, Yufeng Shen, Zhengzheng Wan, Cristian Coarfa, Rafal Drabek, Lei Chen, Elizabeth A. Ostrowski, Yue Liu, George M. Weinstock, David A. Wheeler, Richard A. Gibbs, and Fuli Yu

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Cat-Map: Putting cataract on the map, Alan Shiels, Thomas M. Bennett, and J. Fielding Hejtmancik

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The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1, Bimmi Shrestha, James D. Brien, Soila Sukupolvi-Petty, S. Kyle Austin, Melissa A. Edeling, Taekyung Kim, Katie M. O'Brien, Christopher A. Nelson, Syd Johnson, Daved H. Fremont, and Michael S. Diamond

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Perspectives on: Molecular dynamics and computational methods Multi-scale electrophysiology modeling: from atom to organ, Jonathan R. Silva and Yoram Rudy

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Parental depression and offspring psychopathology: A Children of Twins study, A. L. Singh, B. M. D'Onofrio, W. S. Slutske, E. Turkheimer, R. E. Emery, K. P. Harden, A. C. Heath, P. A F Madden, D. J. Statham, and N. G. Martin

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Cisplatin ototoxicity blocks sensory regeneration in the avian inner ear, Eric L. Slattery and Mark E. Warchol

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A functional metagenomic approach for expanding the synthetic biology toolbox for biomass conversion, Morten O. A. Sommer, George M. Church, and Gautam Dantas

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The human microbiome harbors a diverse reservoir of antibiotic resistance genes, Morten O.A. Sommer, George M. Church, and Gautam Dantas

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Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction, Claus S. Sondergaard, David A. Hess, Dustin J. Maxwell, Carla Weinheimer, Ivana Rosová, Michael H. Creer, David Piwnica-Worms, Attila Kovacs, Lene Pedersen, and Jan A. Nolta

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Genetic and environmental influences on internalizing psychopathology vary as a function of economic status, S. C. South and R. F. Krueger

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The contraceptive CHOICE project: Recruiting women at highest risk for unintended pregnancy and sexually transmitted infection, Janine E. Spain, Jeffrey F. Peipert, Tessa Madden, Jenifer E. Allsworth, and Gina M. Secura

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Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii, Tobias Steinfeldt, Stephanie Konen-Waisman, Lan Tong, Nikolaus Pawlowski, Tobias Lamkemeyer, L. David Sibley, Julia P. Hunn, and Jonathan C. Howard

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Consuming cassava as a staple food places children 2-5 years old at risk for inadequate protein intake, an observational study in Kenya and Nigeria, Kevin Stephenson, Rachel Amthor, Sally Mallowa, Rhoda Nungo, Busie Maziya-Dixon, Simon Gichuki, Ada Mbanaso, and Mark Manary

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Expression of the BabA adhesin during experimental infection with Helicobacter pylori, Cathy M. Styer, Lori M. Hansen, Cara L. Cooke, Amy M. Gundersen, Sung Sook Choi, Douglas E. Berg, Mohammed Benghezal, Barry J. Marshall, Richard M. Peek Jr, Thomas Boren, and Jay V. Solnick

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Genome-wide association study of Lp-PLA2 activity and mass in the Framingham Heart Study, Sunil Suchindran, David Rivedal, John R. Guyton, Tom Milledge, Xiaoyi Gao, Ashlee Benjamin, Jennifer Rowell, Geoffrey S. Ginsburg, and Jeanette J. McCarthy

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Health and life insurance as an alternative to malpractice tort law, Walton Sumner II

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Glucocorticoid protection of oligodendrocytes against excitotoxin involving hypoxia-inducible factor-1alpha in a cell-type-specific manner, Yu-Yo Sun, Chen-Yu Wang, Ming-Feng Hsu, Shu-Hui Juan, Chiu-Yun Chang, Chih-Ming Chou, Liang-Yo Yang, Kuo-Sheng Hung, Jan Xu, Yi-Hsuan Lee, and Chung Y. Hsu

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IPS-1 is essential for the control of West Nile virus infection and immunity, Mehul S. Suthar, Daphne Y. Ma, Sunil Thomas, Jennifer M. Lund, Nu Zhang, Stephane Daffis, Alexander Y. Rudensky, Michael J. Bevan, Edward A. Clark, Murali-Krishna Kaja, Michael S. Diamond, and Michael Gale Jr.

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Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response, Cristina L. Swanson, Timothy J. Wilson, Pamela Strauch, Marco Colonna, Roberta Pelanda, and Raul M. Torres

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Revised SHEA position paper: Influenza vaccination of healthcare personnel, Thomas R. Talbot, Hilary Babcock, Arthur L. Caplan, Deborah Cotton, Lisa L. Maragakis, Gregory A. Poland, Edward J. Septimus, Michael L. Tapper, and David J. Weber

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Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine, Qiong-Yao Tang, Zhe Zhang, Xiao-Ming Xia, and Christopher J. Lingle

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The perilipin homologue, Lipid storage droplet 2, regulates sleep homeostasis and prevents learning impairments following sleep loss, Matthew S. Thimgan, Yasuko Suzuki, Laurent Seugnet, Laura Gottschalk, and Paul J. Shaw

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RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation, Xiaolin Tian, Ramon U. Jin, Andrew J. Bredemeyer, Edward J. Oates, Katatzyna M. Blazewska, Charles E. McKenna, and Jason C. Mills

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Neonatal intravenous injection of a gammaretroviral vector has a low incidence of tumor induction in mice, Mindy Tittiger, Xiuxui Ma, Lingfei Xu, and Katherine P. Ponder

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Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, and Charles F. Zorumski

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Detection rates of congenital heart disease in Guatemala, Sara M. Trucco, Joaquin Barnoya, Luis A. Larrazabal, Aldo Castañeda, and David F. Teitel

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CD46 engagement on human CD4+ T cells produces T regulatory type 1-like regulation of antimycobacterial T cell responses, Steven M. Truscott, Getahun Abate, Jeffrey D. Price, Claudia Kemper, John P. Atkinson, and Daniel F. Hoft

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Roles of membrane trafficking in nerve repair and regeneration, Elizabeth Tuck and Valeria Cavalli

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Image-based calibration of a deformable mirror in wide-field microscopy, Diwakar Turaga and Timothy E. Holy

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Full tensor diffucion is not required to access the white-matter integrity in mouse contusion spinal cord injury, Tsang-Wei Tu, Joong H. Kim, Jian Wang, and Sheng-Kwei Song

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High-throughput discovery of rare insertions and deletions in large cohorts, Francesco L.M. Vallania, Todd E. Druley, Enrique Ramos, Jue Wang, Ingrid Borecki, Michael Province, and Robi D. Mitra

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Bisulfite Patch PCR enables multiplexed sequencing of promoter methylation across cancer samples, Katherine Elena Varley and Robi David Mitra

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Perceptions of HIV risk among monogamous wives of alcoholic men in South India: A qualitative study, Deepthi S. Varma, Prabha S. Chandra, Catina Callahan, Wendy Reich, and Linda B. Cottler

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Management of patients with advanced non-small cell lung cancer: role of gefitinib, Vamsidhar Velcheti, Daniel Morgensztern, and Ramaswamy Govindan

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Is transcription factor binding site turnover a sufficient explanation for cis-regulatory sequence divergence?, Sandeep Venkataram and Justin C. Fay

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Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway, Bhupinder P.S. Vohra, Yo Sasaki, Bradley R. Miller, Jufang Chang, Aaron DiAntonio, and Jeffrey Milbrandt

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Risk of miscarriage with bivalent vaccine against human papillomavirus (HPV) types 16 and 18: Pooled analysis of two randomised controlled trials, Sholom Wacholder, Bingshu Eric Chen, Allen Wilcox, George Macones, Paula Gonzalez, Brian Befano, Allan Hildesheim, Ana Cecilia Rodriguez, Diane Solomon, Rolando Herrero, and Mark Schiffman

Identification of YsrT and evidence that YsrRST constitute a unique phosphorelay system in Yersinia enterocolitica, Kimberly A. Walker, Markus W. Obrist, Shirly Mildiner-Earley, and Virginia L. Miller

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Identification of YsrT and evidence that YsrRST constitute a unique phosphorelay system in Yersinia enterocolitica, Kimberly A. Walker, Markus W. Obrist, Shirly Mildiner-Earley, and Virginia L. Miller

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TIP-1 translocation onto the cell plasma membrane is a molecular biomarker of tumor response to ionizing radiation, Hailun Wang, Heping Yan, Allie Fu, Miaojun Han, Dennis Hallahan, and Zhaozhong Han

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The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function, Hongtao Wang, Inna Hughes, William Planer, Alexander Parsadanian, John R. Grider, Bhupinder P.S. Vohra, Cynthia Keller-Peck, and Robert O. Heuckeroth

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Mitochondrial dysfunction and apoptosis in cumulus cells of type I diabetic mice, Qiang Wang, Antonina I. Frolova, Scott Purcell, Katie Adastra, Erica Schoeller, Maggie M. Chi, Tim Schedl, and Kelle H. Moley

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Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation, Zhengyuan Wang, Sahar Abubucker, John Martin, Richard K. Wilson, John Hawdon, and Makedonka Mitreva

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Novel venom gene discovery in the platypus, Camilla M. Whittington, Anthony T. Papenfuss, Devin P. Locke, Elaine R. Mardis, Richard K. Wilson, Sahar Abubucker, Makedonka Mitreva, Emily SW Wong, Arthur L. Hsu, Philip W. Kuchel, Katherine Belov, and Wesley C. Warren

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Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis, Timothy J. Wilding, Kevin Chen, and James E. Huettner

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Visualizing lens epithelial cell proliferation in whole lenses, Luke A. Wiley, Ying-Bo Shui, and David C. Beebe

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Quantitative cardiovascular magnetic resonance for molecular imaging, Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza, and Samuel A. Wickline

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Physical activity in US Blacks: a systematic review and critical examination of self-report instruments, Kathleen Y. Wolin, Casey Fagin, Nneka Ufere, Hallie Tuchman, and Gary G. Bennett

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State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation, Dick Wu, Kelli Delaloye, Mark A. Zaydman, Ali Nekouzadeh, Yoram Rudy, and Jianmin Cui

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Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia, Zhifu Xiang, Hui Luo, Jacqueline E. Payton, Jennifer Cain, Timothy J. Ley, Joseph T. Opferman, and Michael H. Tomasson

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Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron DiAntonio, and Catherine A. Collins

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Relationship between complex and simple spike activity in macaque caudal vermis during three-dimensional vestibular stimulation, Tatyana Yakusheva, Pablo M. Blazquez, and Dora E. Angelaki

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NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis, Chang Yang, Kathleen McCoy, Jennifer L. Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, and Deborah Veis Novack

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Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis, Jingxuan Yang, Michael Meyer, Anna-Katharina Müller, Friederike Böhm, Richard Grose, Tina Dauwalder, Francois Verrey, Manfred Kopf, Juha Partanen, Wilhelm Bloch, David M. Ornitz, and Sabine Werner

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Application of X STOP device in the treatment of lumbar spinal stenosis, Xiaobin Yi and Bradley McPherson

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Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas, Anas Younes, Nancy L. Bartlett, John P. Leonard, Dana A. Kennedy, Carmel M. Lynch, Eric L. Sievers, and Andres Forero-Torres

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Behavioral consequences of NMDA antagonist-induced neuroapoptosis in the infant mouse brain, Carla M. Yuede, David F. Wozniak, Catherine E. Creeley, George T. Taylor, John W. Olney, and Nuri B. Farber

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Enhanced hepatic apoA-I secretion and peripheral efflux of cholesterol and phospholipid in CD36 null mice, Pin Yue, Zhouji Chen, Fatiha Nassir, Carlos Bernal-Mizrachi, Brian Finck, Salman Azhar, and Nada A. Abumrad

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Ribosomal RNA diversity predicts genome diversity in gut bacteria and their relatives, Jesse R. Zaneveld, Catherine Lozupone, Jeffrey I. Gordon, and Rob Knight

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Conservation and divergence of microRNAs and their functions in Euphorbiaceous plants, Changying Zeng, Wenquan Wang, Yun Zheng, Xin Chen, Weiping Bo, Shun Song, Weixiong Zhang, and Ming Ping

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Regulation of cell death and epileptogenesis by the mammalian target of rapamycin (mTOR): A double-edged sword?, Ling-Hui Zeng, Sharon McDaniel, Nicholas R. Rensing, and Michael Wong

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Multiple distinct small RNAs originate from the same microRNA precursors, Weixiong Zhang, Shang Gao, Xuefeng Zhou, Jing Xia, Padmanabhan Chellappan, Xiang Zhou, Xiaoming Zhang, and Hailing Jin

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Diagnosis of pulmonary tuberculosis among asymptomatic HIV+ patients in Guangxi, China, Yao Zhang, Lan Yu, Zhi-rong Tang, Shao-biao Huang, Yuan-jia Zheng, Zhi-hao Meng, Kai Sun, Li-ming Wang, Ray Y. Chen, and Fu-jie Zhang

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Gamma-secretase composed of PS1/Pen2/Aph1a can cleave notch and amyloid precursor protein in the absence of nicastrin, Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, and Raphael Kopan

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Glycine311, a determinant of paxilline block in BK channels: A novel bend in the BK S6 helix, Yu Zhou, Qiong-Yao Tang, Xiao-Ming Xia, and Christopher J. Lingle

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Herbaspirillum species bacteremia in a pediatric oncology patient, Edward D. Ziga, Todd Druley, and Carey-Ann D. Burnham

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Inappropriate empiric antifungal therapy for candidemia in the ICU and hospital resource utilization: a retrospective cohort study, Marya D. Zilberberg, Marin H. Kollef, Heather Arnold, Andrew Labelle, Scott T. Micek, Smita Kothari, and Andrew F. Shorr

Submissions from 2009

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Mutations in ampG and lytic transglycosylase genes affect the net release of peptidoglycan monomers from Vibrio fischeri, Dawn M. Adin, Jacquelyn T. Engle, William E. Goldman, Margaret J. McFall-Ngai, and Eric V. Stabb

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Item response modeling of DSM-IV mania symptoms in two representative US epidemiological samples, A. Agrawal, J. I. Nurnberger Jr., and M. T. Lynskey