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Submissions from 2007

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Mutational analysis of EGFR and related signaling pathway genes in lung adenocarcinomas identifies a novel somatic kinase domain mutation in FGFR4, Michael D. McLellan, Yumi Kasai, Tracie L. Milner, Ginger A. Fewell, Lucinda L. Fulton, Elaine R. Mardis, Richard K. Wilson, and et al.

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PI3K(p110α) inhibitors as anti-cancer agents: Minding the heart, Julie R. McMullen and Patrick Y. Jay

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Health care-associated pneumonia and community-acquired pneumonia: A single-center experience, Scott T. Micek, Katherine E. Kollef, Richard M. Reichley, Nareg Roubinian, and Marin H. Kollef

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Addition of vasopressin to norepinephrine as independent predictor of mortality in patients with refractory septic shock: An observational study, Scott T. Micek, Poorvi Shah, James M. Hollands, Rina A. Shah, William D. Shannon, and Marin H. Kollef

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Exploring the inter-relationship of smoking age-at-onset, cigarette consumption and smoking persistence: Genes or environment?, Katherine I. Morley, Michael T. Lynskey, Pamela A F Madden, Susan A. Treloar, Andrew C. Heath, and Nicholas G. Martin

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Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model, John D. Morrey, Venkatraman Siddharthan, Aaron L. Olsen, Hong Wang, Justin G. Julander, Jeffery O. Hall, Hua Li, Jeffrey L. Nordstrom, Scott Koenig, Syd Johnson, and Michael S. Diamond

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Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease, Odity Mukherjee, John SK Kauwe, Kevin Mayo, John C. Morris, and Alison M. Goate

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Artemisinin induces calcium-dependent protein secretion in the protozoan parasite Toxoplasma gondii, Kisaburo Nagamune, Wandy L. Beatty, and L. David Sibley

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Artemisinin-resistant mutants of Toxoplasma gondii have altered calcium homeostasis, Kisaburo Nagamune, Silvia N.J. Moreno, and L. David Sibley

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MultiCode-PLx system for multiplexed detection of seventeen respiratory viruses, Frederick S. Nolte, David J. Marshall, Christopher Rasberry, Sabina Schievelbein, Grier G. Banks, Gregory A. Storch, Max Q. Arens, Richard S. Buller, and James R. Prudent

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Rapid maturation of effector T cells in tumors, but not lymphoid organs, during tumor regression, Lyse A. Norian and Paul M. Allen

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Relationship of functional gastrointestinal disorders and psychiatric disorders: Implications for treatment, Carol S. North, Barry A. Hong, and David H. Alpers

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Compartmental pharmacokinetic analysis of oral amprenavir with secondary peaks, Olanrewaju Okusanya, Alan Forrest, Robin DiFrancesco, Sanela Bilic, Susan Rosenkranz, Michael F. Para, Elizabeth Adams, Kevin E. Yarasheski, Richard C. Reichman, Gene D. Morse, and ACTG 5043 Protocol Team

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Site-1 protease is essential for endochondral bone formation in mice, Debabrata Patra, Xiaoyun Xing, Sherri Davies, Jennifer Bryan, Carl Franz, Ernst B. Hunziker, and Linda J. Sandell

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Toward an understanding of risk factors for anorexia nervosa: A case-control study, K. M. Pike, A. Hilbert, D. E. Wilfley, C. G. Fairburn, F. A. Dohm, B. T. Walsh, and R. Striegel-Moore

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Clinical significance of αII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury, Jose A. Pineda, Stephen B. Lewis, Alex B. Valadka, Linda Papa, H. Julia Hannay, Shelley C. Heaton, Jason A. Demery, Ming Cheng Liu, Jada M. Aikman, Veronica Akle, Gretchen M. Brophy, Joseph J. Tepas III, Kevin K. W. Wang, Claudia S. Robertson, and Ronald L. Hayes

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Intracellular mediators of transforming growth factor β superfamily signaling localize to endosomes in chicken embryo and mouse lenses in vivo, Ramya Rajagopal, Shunsuke Ishii, and David C. Beebe

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Polony analysis of gene expression in ES cells and blastocysts, C. Rieger, R. Poppino, R. Sheridan, K. Moley, R. Mitra, and D. Gottlieb

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Molecular refinement of gibbon genome rearrangements, Roberta Roberto, Oronzo Capozzi, Richard K. Wilson, Elaine R. Mardis, Mariana Lomiento, Eray Tuzun, Ze Cheng, Alan R. Mootnick, Nicoletta Archidiacono, Mariano Rocchi, and Evan E. Eichler

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Anionic lipids enriched at the ExPortal of Streptococcus pyogenes, Jason W. Rosch, Fong Fu Hsu, and Michael G. Caparon

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Detection of intracellular bacterial communities in human urinary tract infection, David A. Rosen, Thomas M. Hooton, Walter E. Stamm, Peter A. Humphrey, and Scott J. Hultgren

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Antiretroviral drug levels and interactions affect lipid, lipoprotein, and glucose metabolism in HIV-1 seronegative subjects: A pharmacokinetic- pharmacodynamic analysis, Susan Rosenkranz, Kevin E. Yarasheski, Michael F. Para, Richard C. Reichman, and Gene D. Morse

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Identification and characterization of small molecules that inhibit intracellular toxin transport, Jose B. Saenz, Teresa A. Doggett, and David B. Haslam

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Conduct disorder among Asians and Native Hawaiian/Pacific Islanders in the USA, J. T. Sakai, N. K. Risk, C. A. Tanaka, and R. K. Price

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Fine mapping of mouse QTLs for fatness using SNP data, Armin O. Schmitt, Hadi Al-Hasani, James M. Cheverud, Daniel Pomp, Lutz Bünger, and Gudrun A. Brockmann

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Increasing incidence of sterile-site infections due to non-multidrug- resistant, oxacillin-resistant Staphylococcus aureus among hospitalized patients, Garrett E. Schramm, Jennifer A. Johnson, Joshua A. Doherty, Scott T. Micek, and Marin H. Kollef

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Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: A before-after trial, Douglas J E Schuerer, Ingrid B. Borecki, David K. Warren, Victoria J. Fraser, John E. Mazuski, Walter A. Boyle, Timothy G. Buchman, Craig M. Coppersmith, and et al

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X-linked idiopathic infantile nystagmus associated with a missense mutation in FRMD7, Alan Shiels, Thomas M. Bennett, Jessica B. Prince, and Lawrence Tychsen

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Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice, Jiusong Sun, Galina K. Sukhova, Min Yang, Paul J. Wolters, Lindsey A. MacFarlane, Peter Libby, Chingxiu Sun, Yadong Zhang, Jian Liu, Terri L. Ennis, Rebecca Knispel, Wanfen Xiong, Robert W. Thompson, B. Timothy Baxter, and Guo-Ping Shi

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The neuroendocrine impact of chronic stress on cancer, Premal H. Thaker, Susan K. Lutgendorf, and Anil K. Sood

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Causing and curing infantile esotropia in primates: The role of decorrelated binocular input (an American Ophthalmological Society thesis), Lawrence Tychsen

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Differences in rust in hearing aid batteries across four manufacturers, four battery sizes, and five durations of exposure, Michael Valente, Jamie H. Cadieux, Laura Flowers, John G. Newman, Juergen Scherer, and Gerg Gephart

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Identification and expression of Hop, an atypical homeobox gene expressed late in lens fiber cell terminal differentiation, Oleg Vasiliev, Simon J. Rhodes, and David C. Beebe

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Metastatic disease to the breast: the Washington University experience, Aislinn Vaughan, Jill R. Dietz, Jeffrey F. Moley, Mary K. DeBenedetti, Rebecca L. Aft, William E. Gillanders, Timothy J. Eberlein, Jon Ritter, and Julie A. Margenthaler

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Prospective randomized comparison of cutting and dilating disposable trocars for access during laparoscopic renal surgery, Ramakrishna Venkatesh, Chandru P. Sundaram, Robert S. Figenshau, Yan Yan, Gerald L. Andriole, Ralph V. Clayman, and Jaime Landman

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Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms, Suzanne E. Wahrle, Aarti R. Shah, Anne M. Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J. Thal, Alison M. Goate, and David M. Holtzman

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Age at first sexual intercourse and teenage pregnancy in Australian female twins, Mary Waldron, Andrew C. Heath, Eric Turkheimer, Robert Emery, Kathleen K. Bucholz, Pamela A.F. Madden, and Nicholas G. Martin

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Calling cards for DNA-binding proteins, Haoyi Wang, Mark Johnston, and Robi David Mitra

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Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3, Xiaoli Wang, Roger A. Herr, Wei-Jen Chua, Lonnie Lybarger, Emmanuel J.H.J. Wiertz, and Ted H. Hansen

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Symposium integrating evidence-based medicine into clinical practice, Rick W. Wright, John E. Kuhn, Annunziato Amendola, Morgan H. Jones, and Kurt P. Spindler

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DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth, Chunlai Wu, Richard W. Daniels, and Aaron DiAntonio

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An investigation of the effects of lipid-lowering medications: Genome-wide linkage analysis of lipids in the HyperGEN study, Jun Wu, Michael A. Province, Hilary Coon, Steven C. Hunt, John H. Eckfeldt, Donna K. Arnett, Gerardo Heiss, Cora E. Lewis, R Curtis Ellison, Dabeeru C. Rao, Treva Rice, and Aldi T. Kraja

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Neoplasia driven by mutant c-KIT Is mediated by intracellular, not plasma membrane, receptor signaling, Zhifu Xiang, Frederike Kreisel, Jennifer Cain, AnnaLynn Colson, and Michael H. Tomasson

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Genetic and environmental contributions to pathological gambling symptoms in a 10-year follow-up, Hong Xian, Jeffrey F. Scherrer, Wendy S. Slutske, Kamini R. Shah, Rachel Volberg, and Seth A. Eisen

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Evolution of symbiotic bacteria in the distal human intestine, Jian Xu, Michael A. Mahowald, Ruth E. Lay, Catherine A. Lozupone, Micah Hamady, Eric C. Martens, Bernard Henrissat, Pedro M. Coutinho, Patrick Minx, Philippe Latreille, Holland Cordum, Andrew Van Brunt, Kyung Kim, Robert S. Fulton, Lucinda A. Fulton, Sandra W. Clifton, Richard K. Wilson, Robin D. Knight, and Jeffrey I. Gordon

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Shotgun lipidomics identifies a paired rule for the presence of isomeric ether phospholipid molecular species, Kui Yang, Zhongdan Zhao, Richard W. Gross, and Xianlin Han

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Coronavirus replication does not require the autophagy gene ATG5, Zijiang Zhao, Larissa B. Thackray, Brian C. Miller, Teresa M. Lynn, Michelle M. Becker, Eric Ward, Noboru N. Mizushima, Mark R. Denison, and Herbert W. Virgin

Submissions from 2006

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Contrasting models of genetic co-morbidity for cannabis and other illicit drugs in adult Australian twins, A. Agrawal, M. T. Lynskey, K. K. Bucholz, N. G. Martin, P. A F Madden, and A. C. Heath

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Alteration in irrigant flow and deflection of flexible ureteroscopes with Nitinol baskets, Caroline D. Ames, Juan M. Perrone, Kyle J. Weld, Kelley V. Foyil, Yan Yan, Ramakrishna Venkatesh, and Jaime Landman

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Pharmacologic manipulation of the porcine ureter: Acute impact of topical drugs on ureteral diameter and peristaltic activity, Caroline D. Ames, Kyle J. Weld, Stephen T. Dryer, Greg Hruby, Scott D. Minor, Yan Yan, Robert S. Figenshau, Sam Bhayani, Jaime Landman, and Ramakrishna Venkatesh

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Evaluation of laparoscopic performance with alteration in angle of vision, Caroline Ames, Alison J. Frisella, Yan Yan, Peter Shulam, and Jaime Landman

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C5a and Fcγ receptors: A mutual admiration society, John P. Atkinson

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Bypassing complement: Evolutionary lessons and future implications, John P. Atkinson and Michael M. Frank

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Effect of exercise training on in vitro LDL oxidation and free radical-induced hemolysis: The HERITAGE family study, Denis Blache, Suzanne Lussier-Cacan, Jacques Gagnon, Arthur S. Leon, D.C. Rao, James S. Skinner, Jack H. Wilmore, Tuomo Rankinen, Claude Bouchard, and Jean Davignon

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A systematic model to predict transcriptional regulatory mechanisms based on overrepresentation of transcription factor binding profiles, Li-Wei Chang, Rakesh Nagarajan, Jeffrey A. Magee, Jeffrey Milbrandt, and Gary D. Stormo

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Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: A possible mechanism for the analgesic effect of L-acetylcarnitine, Santina Chiechio, Agata Copani, Laura De Petris, Maria Elena P. Morales, Ferdinando Nicoletti, and Robert W. Gereau IV

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Characterization of multimeric complexes formed by the human PTB1 protein on RNA, Caroline Clerte and Kathleen B. Hall

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Toll-like receptors and IFN-α: Partners in autoimmunity, Marco Colonna

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Mechanisms of sympathoadrenal failure and hypoglycemia in diabetes, Philip E. Cryer

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The type and frequency of fetal renal disorders and management of renal pelvis dilatation, Jeffrey M. Dicke, Valerie M. Blanco, Yan Yan, and Douglas E. Coplen

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Relationships between upper-limb functional limitation and self-reported disability 3 months after stroke, Alexander W. Dromerick, Catherine E. Lang, Rebecca Birkenmeier, Michele G. Hahn, Shirley A. Sahrmann, and Dorothy F. Edwards

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Surfactant protein D increases fusion of Mycobacterium tuberculosis- containing phagosomes with lysosomes in human macrophages, J Scott Ferguson, Jennifer L. Martin, Abul K. Azad, Travis R. McCarthy, Peter B. Kang, Dennis R. Voelker, Erika C. Crouch, and Larry S. Schlesinger

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PGC-1 coactivators: Inducible regulators of energy metabolism in health and disease, Brian N. Finck and Daniel P. Kelly

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Volumetric measurements of lung nodules with multi-detector row CT: Effect of changes in lung volume, Jin Mo Goo, Kwang Gi Kim, David S. Gierada, Mario Castro, and Kyongtae T. Bae

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A phase I trial of docetaxel and vinorelbine in patients with advanced non-small cell lung cancer, Ramaswamy Govindan, Wan-Teck Lim, Matthew A. Arquette, Sherry A. Goodner, Carole L. Fears, Joanne E. Mortimer, and Paula M. Fracasso

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Chemokine signaling regulates apoptosis as well as immune cell traffic in host defense, Mitchell H. Grayson and Michael J. Holtzman

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Harnessing preclinical mouse models to inform human clinical cancer trials, David H. Gutmann, Kim Hunter-Schaedle, and Kevin M. Shannon

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Mechanistic insights into the regulation of the spermatogonial stem cell niche, Rex A. Hess, Paul S. Cooke, Marie-Claude Hofmann, and Kenneth M. Murphy

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Elastin fragments drive disease progression in a murine model of emphysema, A. McGarry Houghton, Pablo A. Quintero, David L. Perkins, Dale K. Kobayashi, Diane G. Kelley, Luiz A. Marconcini, Robert P. Mecham, Robert M. Senior, and Steven D. Shapiro

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Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin, Tobias B. Huber, Christopher Kwoh, Hui Wu, Katsuhiko Asanuma, Markus Gödel, Björn Hartleben, Ken J. Blumer, Jeffrey H. Miner, Peter Mundel, and Andrey S. Shaw

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Proteinuria precedes podocyte abnormalities in Lamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier, George Jarad, Jeanette Cunningham, Andrey S. Shaw, and Jeffrey H. Miner

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Human sensory-evoked responses differ coincident with either "fusion-memory" or "flash-memory", as shown by stimulus repetition-rate effects, Don L. Jewett, Toryalai Hart, Linda J. Larson-Prior, Bill Baird, Marram Olson, Michael Trumpis, Katherine Makayed, and Payam Bavafa

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Dual infection with Mycobacterium tuberculosis and Pneumocystis jiroveci lymphadenitis in a patient with HIV infection: case report and review of the literature, Thana Khawcharoenporn, Anucha Apisarnthanarak, Dussadee Sakonlaya, Linda M. Mundy, and Thomas C. Bailey

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Glucocorticoids suppress bone formation via the osteoclast, Hyun-Ju Kim, Haibo Zhao, Hideki Kitaura, Sandip Bhattacharyya, Judson A. Brewer, Louis J. Muglia, Patrick Ross, and Steven L. Teitelbaum

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Maternal alcohol use disorder and offspring ADHD: Disentangling genetic and environmental effects using a children-of-twins design, Valerie S. Knopik, Andrew C. Heath, Theodore Jacob, Wendy S. Slutske, Kathleen K. Bucholz, Pamela A F Madden, Mary Waldron, and Nicholas G. Martin

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The intensive care unit as a research laboratory: Developing strategies to prevent antimicrobial resistance, Marin H. Kollef

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Blinded comparison of repetitive-sequence PCR and multilocus sequence typing for genotyping methicillin-resistant Staphylococcus aureus isolates from a children's hospital in St. Louis, Missouri, Robert S. Liao, Gregory A. Storch, Richard S. Buller, Rachel C. Orscheln, Elaine R. Mardis, Jon R. Armstrong, and W. Michael Dunne Jr.

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Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a model for in vivo gene expression, Jennifer A. Loughman and Michael Caparon

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Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy, Joan Luby, Christine Mrakotsky, Melissa Meade Stalets, Andy Belden, Amy Heffelfinger, Meghan Williams, and Edward Spitznagel

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PLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2, Dailing Mao, Holly Epple, Brian Uthgenannt, Deborah V. Novack, and Roberta Faccio

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Physical map-assisted whole-genome shotgun sequence assemblies, David Messina, Shiaw-Pyng Yang, Wesley C. Warren, John W. Wallis, LaDeana W. Hillier, Asif T. Chinwalla, and Richard K. Wilson

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Development of the minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE), Jason C. Mills and et al

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Biology and genome of Trichinella spiralis, Makedonka Mitreva and Douglas P. Jasmer

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Codon usage patterns in Nematoda: Analysis based on over 25 million codons in thirty-two species, Makedonka Mitreva, Michael C. Wendl, John Martin, Todd Wylie, Yong Yin, Allan Larson, John Parkinson, Robert H. Waterston, and James P. McCarter

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Childhood sexual abuse and risks for licit and illicit drug-related outcomes: A twin study, Elliot C. Nelson, Andrew C. Heath, Michael T. Lynskey, Kathleen K. Bucholz, Pamela A F Madden, Dixie J. Statham, and Nicholas G. Martin

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Genotyping of toxoplasma gondii by multiplex PCR and peptide-based serological testing of samples from infants in Poland diagnosed with congenital toxoplasmosis, Dorota Nowakowska, Iris Colon, Jack S. Remington, Michael Grigg, Elzbieta Golab, J. Wilczynski, and L. D. Sibley

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Evaluating the efficiency of using second-trimester nasal bone hypoplasia as a single or a combined marker for fetal aneuploidy, Anthony O. Odibo, Harish M. Sehdev, Laura Sproat, Claudia Parra, Linda Odibo, Linda Dunn, and George A. Macones

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Genetic analyses of DSM-IV nicotine withdrawal in adult twins, Michele L. Pergadia, Andrew C. Heath, Nicholas G. Martin, and Pamela A F Madden

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Ciprofloxacin-resistant gram-negative bacilli in the fecal microflora of children, Xuan Qin, Yasmin Razia, James R. Johnson, Jennifer R. Stapp, Daniel R. Boster, Treva Tsosie, Donna L. Smith, Christopher R. Braden, Kathryn Gay, Frederick J. Angulo, and Phillip I. Tarr

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A real-time PCR-based assay for detection of Wuchereria bancrofti DNA in blood and mosquitoes, Ramakrishna U. Rao, Laura J. Atkinson, Reda M.R. Ramzy, Hanan Helmy, Hoda A. Farid, Moses J. Bockarie, Melinda Susapu, Sandra J. Laney, Steven A. Williams, and Gary J. Weil

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Detection of Brugia parasite DNA in human blood by real-time PCR, Ramakrishna U. Rao, Gary J. Weil, Kerstin Fischer, Taniawati Supali, and Peter Fischer

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Expression of putative virulence factors of Escherichia coli O157:H7 differs in bovine and human infections, Rebecca A. Rashid, Tami A. Tabata, Melissa J. Oatley, Thomas E. Besser, Phillip I. Tarr, and Steve L. Moseley

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Insulin resistance and atherosclerosis, Clay F. Semenkovich

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Geminin's double life: Chromatin connections that regulate transcription at the transition from proliferation to differentiation, Seongjin Seo and Kristen L. Kroll

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Blocking monoclonal antibodies specific for mouse IFN-α/β receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection, Kathleen C F Sheehan, Koon Siew Lai, Gavin P. Dunn, Allen T. Bruce, Mark S. Diamond, Jennifer D. Heutel, Corazon Dungo-Arthur, Javier A. Carrero, J. Michael White, Paul J. Herzog, and Robert D. Schreiber

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PKR-dependent autophagic degradation of herpes simplex virus type 1, Zsolt Talloczy, Herbert W. Virgin IV, and Beth Levine

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Cortactin has an essential and specific role in osteoclast actin assembly, Shandiz Tehrani, Roberta Faccio, Indra Chandrasekar, F. Patrick Ross, and John A. Cooper

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The alchemy of tendon repair: A primer for the (S)mad scientist, Dwight A. Towler and Richard H. Gelberman

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Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals, Jeffrey W. Tyner, Edy Y. Kim, Kyotaro Ide, Mark R. Pelletier, William T. Roswit, Jeffrey D. Morton, John T. Battaile, Anand C. Patel, G. Alexander Patterson, Mario Castro, Melanie S. Spoor, Yingjian You, Steven L. Brody, and Michael Holtzman

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Identification of non-dot/icm suppressors of the Legionella pneumophila △dotL lethality phenotype, Carr D. Vincent, Benjamin A. Buscher, Jonathan R. Friedman, Lee Anne Williams, Patrick Bardill, and Joseph P. Vogel