Submissions from 2015
Mobility and safety issues in drivers with dementia, David B. Carr and Desmond O'Neill
Evaluating the optimal definition of abnormal first-trimester uterine artery Doppler parameters to predict adverse pregnancy outcomes, Ebony B. Carter, Katherine Goetzinger, Methodius G. Tuuli, Linda Odibo, Alison G. Cahill, George A. Macones, and Anthony O. Odibo
mTOR and MEK1/2 inhibition differentially modulate tumor growth and the immune microenvironment in syngeneic models of oral cavity cancer, Harrison Cash, Sujay Shah, Ellen Moore, Andria Caruso, Ravindra Uppaluri, Carter Van Waes, and Clint Allen
Asthma is more severe in older adults, Mario Castro and et al
Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma, Mario Castro and et al.
Genomic analysis to define molecular basis of aggressiveness in a mouse model of oral cancer, Varun Chalivendra, Krishna Latha Kanchi, Michael D. Onken, Ashley E. Winkler, Elaine Mardis, and Ravindra Uppaluri
Reduction of parathyroid hormone with vitamin D supplementation in blacks: A randomized controlled trial, Paulette D. Chandler, Foluso Agboola, Kimmie Ng, Jamil B. Scott, Bettina F. Drake, Gary G. Bennett, Andrew T. Chan, Bruce W. Hollis, Karen M. Emmons, Charles S. Fuchs, and Edward L. Giovannucci
Effects of vitamin D supplementation on C-peptide and 25-hydroxyvitamin D concentrations at 3 and 6 months, Paulette D. Chandler, Edward L. Giovannucci, Jamil B. Scott, Gary G. Bennett, Kimmie Ng, Andrew T. Chan, Bruce W. Hollis, Nader Rifai, Karen M. Emmons, Charles S. Fuchs, and Bettina F. Drake
Impact of vitamin D supplementation on adiposity in African-Americans, P D. Chandler, J B. Scott, B F. Drake, K Ng, A T. Chan, B W. Hollis, K M. Emmons, E L. Giovannucci, C S. Fuchs, and G G. Bennett
A latent class analysis of risk factors for acquiring HIV among men who have sex with men: implications for implementing pre-exposure prophylaxis programs, Philip A. Chan, Jennifer Rose, Justine Maher, Stacey Benben, Kristen Pfeiffer, Alexi Almonte, Joanna Poceta, Catherine E. Oldenburg, Sharon Parker, Brandon D.L Marshall, Mickey Lally, Kenneth Mayer, Leandro Mena, Rupa Patel, and Amy S. Nunn
Epigenetic and microRNA regulation during osteoarthritis development, Di Chen, Jie Shen, and Tianqian Hui
Structural analysis of the synthetic Duffy Binding Protein (DBP) antigen DEKnull relevant for Plasmodium vivax malaria vaccine design, Edwin Chen, Nichole D. Salinas, Francis B. Ntumngia, John H. Adams, and Niraj H. Tolia
Aggregate blood pressure responses to serial dietary sodium and potassium intervention: Defining responses using independent component analysis, Gengsheng Chen, Lisa de las Fuentes, Chi C. Gu, Jiang He, Dongfeng Gu, Tanika Kelly, James Hixson, Cashell Jacquish, D. C. Rao, and Treva K. Rice
mTORC1 signaling promotes osteoblast differentiation from preosteoblasts, Jianquan Chen and Fanxin Long
STAT1 modification improves therapeutic effects of interferons on lung cancer cells, Junjie Chen, Jialu Zhao, Lefu Chen, Nian Dong, Zhaojian Ying, Zhenzhen Cai, Dongxiang Ji, Yong Zhang, Li Dong, Yuping Li, Lei Jiang, Michael J. Holtzman, and Chengshui Chen
Myeloid lineage skewing due to exacerbated NF-κB signaling facilitates osteopenia in Scurfy mice, T H-P Chen, G Swarnkar, G Mbalaviele, and Y Abu-Amer
Mouse low-grade gliomas contain cancer stem cells with unique molecular and functional properties, Yi-Hsien Chen, Lucy D'Agostino McGowan, Patrick J. Cimino, Sonika Dahiya, Jeffrey R. Leonard, Da Yong Lee, and David H. Gutmann
Focal segmental glomerulosclerosis: Molecular genetics and targeted therapies, Ying Maggie Chen and Helen Liapis
Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging, Maggie Chi, Kelle H. Moley, and et al
Management and outcomes of traumatic hemothorax in children, Pamela M. Choi, Shannon Farmakis, Thomas J. Desmarais, and Martin S. Keller
Cytosolic phospholipase A 2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway, Dennis Y. Chuang, Agnes Simonyi, Paul T. Kotzbauer, Zezong Gu, and Grace Y. Sun
Albumin-associated free fatty acids induce macropinocytosis in podocytes, Jun-Jae Chung, Tobias B. Huber, Markus Gödel, George Jarad, Björn Hartleben, Christopher Kwoh, Alexander Keil, Aleksey Karpitskiy, Jiancheng Hu, Christine J. Huh, Marina Cella, Richard W. Gross, Jeffrey H. Miner, and Andrey S. Shaw
Obesity and aerobic fitness among urban public school students in elementary, middle, and high school, B. Ruth Clark, M. Leanne White, Nathaniel K. Royer, Tamara L. Burlis, Nicholas C. DuPont, Michael Wallendorf, and Susan B. Racette
Influence of home and school environments on specific dietary behaviors among postpartum, high-risk teens, 27 states, 2007-2009, Megan A. Clarke, Debra L. Haire-Joshu, Cynthia D. Schwarz, Rachel G. Tabak, and Corinne E. Joshu
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders, Paul Cliften, Jeffrey Milbrandt, and et al
Sickle cell disease: Wheeze or asthma?, Robyn T. Cohen, Elizabeth S. Klings, and Robert C. Strunk
Association between dietary patterns during pregnancy and birth size measures in a diverse population in Southern US, Uriyoán Colón-Ramos, Susan B. Racette, Jody Ganiban, Thuy G. Nguyen, Mehmet Kocak, Kecia N. Carroll, Eszter Völgyi, and Frances A. Tylavsky
Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel, Paige E. Cooper, Monica Sala-Rabanal, Sun Joo Lee, and Colin G. Nichols
In vivo kinetic approach reveals slow SOD1 turnover in the CNS, Matthew J. Crisp, Kwasi G. Mawuenyega, Bruce W. Patterson, Naveen C. Reddy, Robert Chott, Wade K. Self, Conrad C. Weihl, Jennifer Jockel-Balsarotti, Arun S. Varadhachary, Robert C. Bucelli, Kevin E. Yarasheski, Randall J. Bateman, and Rimothy M. Miller
Epidemiology, co-infections, and outcomes of viral pneumonia in adults an observational cohort study, Matthew P. Crotty, Shelby Meyers, Nicholas B. Hampton, Stephanie Bledsoe, David J. Ritchie, Richard S. Buller, Gregory A. Storch, Scott T. Micek, and Marin H. Kollef
Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: An opportunity for stewardship, Matthew P. Crotty, Shelby Meyers, Nicholas Hampton, Stephanie Bledsoe, David J. Ritchie, Richard S. Buller, Gregory A. Storch, Marin H. Kollef, and Scott T. Micek
Automatic analysis (aa): Efficient neuroimaging workflows and parallel processing using Matlab and XML, Rhodri Cusack, Alejandro Vicente-Grabovetsky, Daniel J. Mitchell, Conor J. Wild, Tibor Auer, Annika C. Linke, and Jonathan E. Peelle
Butyrate and mucosal inflammation: New scientific evidence supports clinical observation, Kelly Cushing, David M. Alvarado, and Matthew A. Ciorba
Citrulline protects Streptococcus pyogenes from acid stress using the arginine deiminase pathway and the F1Fo-ATPase, Zachary T. Cusumano and Michael G. Caparon
The ATF6 pathway of the ER stress response contributes to enhanced viability in glioblastoma, David Y A Dadey, Vaishali Kapoor, Arpine Khudanyan, Fumihiko Urano, Albert H. Kim, Dinesh Thotala, and Dennis E. Hallahan
Quantitative evaluation of the community research fellows training program, Lucy D'Agostino McGowan, Jewel D. Stafford, Vetta Lynn Thompson, Bethany Johnson-Javois, and Melody S. Goodman
Comparison of automated versus traditional nerve conduction study methods for median nerve testing in a general worker population, Ann Marie Dale, Folasad Agboola, Amber Yun, Angelique Zeringue, Muhammed T. Al-Lozi, and Bradley A. Evanoff
Responsiveness of a 1-year recall modified DASH Work module in active workers with upper extremity musculoskeletal symptoms, Ann Marie Dale, Bethany T. Gardner, Skye Buckner-Petty, Victoria Kaskutas, Jamie Strickland, and Bradley A. Evanoff
Comparison of musculoskeletal disorder health claims between construction floor layers and a general working population, Ann Marie Dale, Daniel Ryan, Laura Welch, Margaret A. Olsen, Bryan Buchholz, and Bradley A. Evanoff
General population job exposure matrix applied to a pooled study of prevalent carpal tunnel syndrome, Ann Marie Dale, Angelique Zeringue, Carisa Harris-Adamson, David Rempel, Stephen Bao, Matthew S. Thiese, Linda Merlino, Susan Burt, Jay Kapellusch, Arun Garg, Fred Gerr, Kurt T. Hegmann, Ellen A. Eisen, and Bradley A. Evanoff
Oxidative stress biomarkers and incidence of postoperative atrial fibrillation in the Omega‐3 Fatty Acids for Prevention of Postoperative Atrial Fibrillation (OPERA) trial, Ralph J. Damiano, Joann Marsala, and et al
Knocking on closed doors: Host interferons dynamically regulate blood-brain barrier function during viral infections of the central nervous system, Brian P. Daniels and Robyn S. Klein
Trends in opioid analgesic abuse and mortality in the United States, Richard C. Dart, Hilary L. Surratt, Theodore J. Cicero, Mark W. Parrino, S Geoff Severtson, Becki Bucher-Bartelson, and Jody L. Green
A case study of voltage-gated potassium channel antibody-related limbic encephalitis with PET/MRI findings, Brian K. Day, Lawrence Eisenman, Joseph Black, Luigi Maccotta, and R. Edward Hogan
Nonverbal reasoning in preschool children: Investigating the putative risk of secondhand smoke exposure and attention-deficit/hyperactivity disorder as a mediator, Duneesha De Alwis, Mini Tandon, Rebecca Tillman, and Joan Luby
Role of ABCA7 loss-of-function variant in Alzheimer's disease: A replication study in European–Americans, Jorge L. Del-Aguila, Maria Victoria Fernandez, Jessica Jimenez, Kathleen Black, Shengmei Ma, Yuetiva Deming, David Carrell, Ben Saef, Bill Howells, John Budde, and Carlos Cruchaga
Lateral epicondylitis: new evidence for work relatedness, Alexis Descatha, Ann Marie Dale, Barbara A. Silverstein, Yves Roquelaure, and David Rempel
Validation of a risk prediction tool for coronary heart disease in middle-aged women, Katerina M. De Vito, Heather J. Baer, Hank Dart, Stephanie E. Chiuve, Eric B. Rimm, and Graham A. Colditz
Preparing for the next epidemic with basic virology, Michael S. Diamond
Germline mutations in predisposition genes in pediatric cancer, Li Ding, Elaine R. Mardis, Richard K. Wilson, and et al
Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I, John F. DiPersio and et al
A consensus-based interpretation of the benchmark evidence from South American trials: treatment of intracranial pressure trial, Michael N. Diringer and et al
Filling in the gaps: Anticipatory control of eye movements in chronic mild traumatic brain injury, Mithun Diwakar, Deborah L. Harrington, Jun Maruta, Jamshid Ghajar, Fady El-Gabalawy, Laura Muzzatti, Maurizio Corbetta, Ming-Xiong Huang, and Roland R. Lee
Preparedness of Ob/Gyn residents for fellowship training in gynecologic oncology, David W. Doo, Matthew Powell, Akiva Novetsky, Jeanelle Sheeder, and Saketh R. Guntupalli
Mitochondrial dynamism and heart disease: Changing shape and shaping change, Gerald W. Dorn II
Mammograms on-the-go—predictors of repeat visits to mobile mammography vans in St Louis, Missouri, USA: A case–control study, Bettina F. Drake, Salmafatima S. Abadin, Sarah Lyons, Su-Hsin Chang, Lauren T. Steward, Susan Kraenzle, and Melody S. Goodman
Toxoplasma actin is required for efficient host cell invasion, Lisa L. Drewry and L. David Sibley
Risk factors for acquisition and loss of Clostridium difficile colonization in hospitalized patients, Erik R. Dubberke, Kimberly A. Reske, Sondra Seiler, Tiffany Hink, Jennie H. Kwon, and Carey-Ann D. Burnham
Response to nodal morphogen gradient is determined by the kinetics of target gene induction, Julien Dubrulle, Benjamin M. Jordan, Laila Akhmetova, Jeffrey A. Farrell, Seok-Hyung Kim, Lilianna Solnica-Krezel, and Alexander F. Schier
Implementing administrative evidence based practices: Lessons from the field in six local health departments across the United States, Kathleen Duggan, Kristelle Aisaka, Rachel G. Tabak, Carson Smith, Paul Erwin, and Ross C. Brownson
Relationship between abuse and neglect in childhood and diabetes in adulthood: Differential effects by sex, national longitudinal study of adolescent health, Alexis E. Duncan, Wendy F. Auslander, Kathleen K. Bucholz, Darrell L. Hudson, Richard I. Stein, and Neil H. White
CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system, Douglas M. Durrant, Brian P. Daniels, TracyJo Pasieka, Denise Dorsey, and Robyn S. Klein
Comparing interventions and exploring neural mechanisms of exercise in Parkinson disease: A study protocol for a randomized controlled trial, Gammon M. Earhart, Ryan P. Duncan, John L. Huang, Joel S. Perlmutter, and Kristen A. Pickett
Kappa Opioid receptor-induced aversion requires p38 MAPK activation in VTA dopamine neurons, Jonathan M. Ehrich, Daniel I. Messinger, Cerise R. Knakal, Jamie R. Kuhar, Selena S. Schatteuer, Michael R. Bruchas, Larry S. Zweifel, Brigitte L. Kieffer, Paul E M Phillips, and Charles Chavkin
Three-year efficacy and safety of a new 52-mg levonorgestrel-releasing intrauterine system, David L. Eisenberg, Courtney A. Schreiber, David K. Turok, Stephanie B. Teal, Carolyn L. Westhoff, Mitchell D. Creinin, and ACCESS IUS Investigators
Emotional eating phenotype is associated with central dopamine D2 receptor binding independent of body mass index, Sarah A. Eisenstein, Allison N. Bischoff, Danuta M. Gradysa, Jo Ann V. Antenor-Dorsey, Jonathan M. Koller, Amal Al-Lozi, Marta Y. Pepino, Samuel Klein, Joel S. Perlmutter, Stephen M. Morelein, Kevin J. Black, and Tamara Hershey
Insulin, central dopamine D2 receptors, and monetary reward discounting in obesity, Sarah A. Eisenstein, Danuta M. Gredysa, Jo Ann Antenor-Dorsey, Leonard Green, Ana Maria Arbelaez, Jonathan M. Koller, Kevin J. Black, Joel S. Perlmutter, Stephen M. Moerlein, and Tamara Hershey
Targeting CD226/DNAX accessory molecule-1 (DNAM-1) in collagen-induced arthritis mouse models, Muriel Elhai, Gilles Chiocchia, Carmen Marchiol, Franck Lager, Gilles Renault, Marco Colonna, Guenter Bernhardt, Yannick Allanore, and Jerome Avouac
Late gastrointestinal tissue effects after hypofractionated radiation therapy of the pancreas, Adnan Elhammali, Mukund Patel, Benjamin Weinberg, Vivek Verma, Jingxia Liu, Jeffrey R. Olsen, and Hiram A. Gay
Diffusion MRI quality control and functional diffusion map results in ACRIN 6677/RTOG 0625: A multicenter, randomized, phase II trial of bevacizumab and chemotherapy in recurrent glioblastoma, Benjamin M. Ellingson, Eunhee Kim, Davis C. Woodworth, Helga Marques, Jerrold L. Boxerman, Yair Safriel, Robert C. McKinstry, Felix Bokstein, Rajan Jain, T. Linda Chi, A. Gregory Sorensen, Mark R. Gilbert, and Daniel P. Barboriak
Intermediate DNA methylation is a conserved signature of genome regulation, GiNell Elliott, Xiaoyun Xing, Xin Zhou, Daofeng Li, Gary D. Stormo, Ting Wang, and et al
Prospective validation of a 21-gene expression assay in breast cancer, Matthew J. Ellis and et al
Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis, Tim S. Ellison, Samuel J. Atkinson, Veronica Steri, Benjamin M. Kirkup, Michael E J Preedy, Robert T. Johnson, Christina Ruhrberg, Dylan R. Edwards, Jochen G. Schneider, Katherine Weilbaecher, and Stephen D. Robinson
Utilization of an Eilat virus-based chimera for serological detection of chikungunya infection, Jesse H. Erasmus, James Needham, Syamal Raychaudhuri, Michael S. Diamond, David W. C. Beasley, Stan Morkowski, Henrik Salje, Ildefonso Fernandez Salas, Dal Young Kim, Ilya Frolov, Farooq Nasar, and Scott C. Weaver
Hepatic steatosis as a marker of metabolic dysfunction, Elisa Fabbrini and Faidon Magkos
Metabolically normal obese people are protected from adverse effects following weight gain, Elisa Fabbrini, Jun Yoshino, Mihoko Yoshino, Faidon Magkos, Courtney T. Luecking, Dmitri Samovski, Gemma Fraterrigo, Adewole L. Okunade, Bruce W. Patterson, and Samuel Klein
Importance of decision support implementation in emergency department vancomycin dosing, Brett Faine, Nicholas Mohr, Kari K. Harland, Kathryn Rolfes, Blake Porter, and Brian M. Fuller
Enterovirus D68-associated acute respiratory distress syndrome in adult, United States, 2014, John J. Farrell, Ossama Ikladios, Kristine M. Wylie, Lindsay M. O'Rourke, Kristin S. Lowery, Jenna S. Cromwell, Todd N. Wylie, Elsa L. Vazquez Melendez, Yves Makhoul, Rangarajan Sampath, Robert A. Bonomo, and Gregory A. Storch
Differential impact of LPG-and PG-deficient Leishmania major mutants on the immune response of human dendritic cells, Michelle A. Favila, Nicholas S. Geraci, Asha Jayakumar, Suzanne Hickerson, Janet Mostrom, Salvatore J. Turco, Stephen M. Beverley, and Mary Ann McDowell
Pathological complete response in breast cancer patients following neoadjuvant chemotherapy at a Comprehensive Cancer Center: The natural history of an elusive prognosticator, Oluwadamilola M. Fayanju, Iheoma Nwaogu, Donna B. Jeffe, and Julie A. Margenthaler
Distance-dependent plasmon-enhanced fluorescence of upconversion nanoparticles using polyelectrolyte multilayers as tunable spacers, Ai Ling Feng, Min Li You, Limei Tian, Srikanth Singamaneni, Ming Liu, Zhenfeng Duan, Tian Jian Lu, Feng Xu, and Min Lin
Does diacylglycerol accumulation in fatty liver disease cause hepatic insulin resistance?, Brian N. Finck and Angela M. Hall
Digynic triploidy: Utility and challenges of noninvasive prenatal testing, Julie Fleischer, Archana Shenoy, Katherine Goetzinger, Catherine E. Cottrell, Dustin Baldridge, Frances V. White, and Marwan Shinawi
Association of knowledge, preventive counseling and personal health behaviors on physical activity and consumption of fruits or vegetables in community health workers, Alex A. Florindo, Ross C. Brownson, Gregore I. Mielke, Grace AO Gomes, Diana C. Parra, Fernando V. Siqueira, Felipe Lobelo, Eduardo J. Simoes, Luiz R. Ramos, Mario M. Bracco, and Pedro C. Hallal
Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners, Stephanie I. Fraley, Yunfeng Feng, Anjil Giri, Gregory D. Longmore, and Denis Wirtz
Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions, Stephanie I. Fraley, Pei-hsun Wu, Lijuan He, Yunfeng Feng, Ranjini Krisnamurthy, Gregory D. Longmore, and Denis Wirtz
Quantitative autism symptom patterns recapitulate differential mechanisms of genetic transmission in single and multiple incidence families, Thomas Frazier, Eric A. Youngstrom, Antonio Y. Hardan, Stelios Georgiades, John N. Constantino, and Charis Eng
Decompressive craniectomy reduces white matter injury after controlled cortical impact in mice, Stuart H. Friess, Jodi B. Lapidus, and David L. Brody
Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications, Anja Fuchs, Timothy J. Wilson, Marco Colonna, and et al
Predicting clinical binary outcome using multivariate longitudinal data: Application to patients with newly diagnosed primary open-angle glaucoma, Feng Gao, J. Philip Miller, Julia A. Beiser, Chengjie Xiong, and Mae O. Gordon
Dual-modality photoacoustic and ultrasound imaging system for noninvasive sentinel lymph node detection in patients with breast cancer, Alejandro Garcia-Uribe, Todd N. Erpelding, Arie Krumholz, Haixin Ke, Konstantin Maslov, Catherine Appelton, Julie A. Margenthaler, and Lihong V. Wang
The N-Terminal domain of SIRT1 is a positive regulator of endogenous SIRT1-dependent deacetylation and transcriptional outputs, Fiorella Ghisays, Cynthia S. Brace, Shawn M. Yackly, Hyock Joo Kwon, Kathryn F. Mills, Elena Kashentseva, Igor P. Dmitriev, David T. Curiel, Shin-ichiro Imai, and Tom Ellenberger
Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects, Paul Giacomin, Martha Zakrzewski, John Croese, Xiaopei Su, Javier Sotillo, Leisa McCann, Severine Navarro, Makedonka Mitreva, Lutz Krause, Alex Loukas, and Cinzia Cantacessi
Extending injury- and disease-resistant CNS phenotypes by repetitive epigenetic conditioning, Jeffrey M. Gidday
The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development, Stefanie Giera, Yiyu Deng, Rong Luo, Sarah D. Ackerman, Amit Mogha, Kelly R. Monk, Yanqin Ying, Sung-Jin Jeong, Manabu Makinodan, Allison R. Bialas, Bernard S. Chang, Beth Stevens, Gabriel Corfas, and Xianhua Piao
The female protective effect in autism spectrum disorder is not mediated by a single genetic locus, Jake Gockley, A. Jeremy Willsey, Shan Dong, Joseph D. Dougherty, John N. Constantino, and Stephan J. Sanders
A rapid bioluminescence assay for measuring myeloperoxidase activity in human plasma, Reece J. Goiffon, Sara C. Martinez, and David Piwnica-Worms
Admixture mapping of coronary artery calcification in African Americans from the NHLBI family heart study, Felicia Gomez, Lihua Wang, Haley Abel, Qunyuan Zhang, Michael A. Province, and Ingrid B. Borecki
Subinhibitory antibiotic therapy alters recurrent urinary tract infection pathogenesis through modulation of bacterial virulence and host immunity, Lee W. Goneau, Thomas J. Hannan, Roderick A. MacPhee, Drew J. Schwartz, Jean M. Macklaim, Gregory B. Gloor, Hassan Razvi, Gregor Reid, Scott J. Hultgren, and Jeremy P. Burton
