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Submissions from 2024

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Genetic and multi-omic resources for Alzheimer disease and related dementia from the Knight Alzheimer Disease Research Center, Maria Victoria Fernandez, Menghan Liu, Aleksandra Beric, Matt Johnson, Arda Cetin, Maulik Patel, John Budde, Pat Kohlfeld, Kristy Bergmann, Joseph Lowery, Allison Flynn, William Brock, Brenda Sanchez Montejo, Jen Gentsch, Nicholas Sykora, Joanne Norton, Jen Gentsch, Olga Valdez, Priyanka Gorijala, Jessie Sanford, Yichen Sun, Ciyang Wang, Dan Western, Jigyasha Timsina, Tassia Mangetti Goncalves, Anh N Do, Yun Ju Sung, Guoyan Zhao, John C Morris, Krista Moulder, David M Holtzman, Randall J Bateman, Celeste Karch, Jason Hassenstab, Chengjie Xiong, Suzanne E Schindler, Joyce Joy Balls-Berry, Tammie L S Benzinger, Richard J Perrin, Andrea Denny, B Joy Snider, Susan L Stark, Laura Ibanez, and Carlos Cruchaga

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Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis, Yoshihiro Hasegawa, Steven L Teitelbaum, and et al.

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Thermodynamic coupling of the tandem RRM domains of hnRNP A1 underlie its pleiotropic RNA binding functions, Jeffrey D Levengood, Davit Potoyan, Srinivasa Penumutchu, Abhishek Kumar, Qianzi Zhou, Yiqing Wang, Alexandar L Hansen, Sebla Kutluay, Julien Roche, and Blanton S Tolbert

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Complications and health-related quality of life in children with various etiologies of early-onset scoliosis treated with magnetically controlled growing rods- A multicenter study, Pawel Glowka, Pawel Grabala, Munish C Gupta, Daniel E Pereira, Michal Latalski, Anna Danielewicz, Michal Grabala, Marek Tomaszewski, and Tomasz Kotwicki

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Dual-localized PPTC7 limits mitophagy through proximal and dynamic interactions with BNIP3 and NIX, Lianjie Wei, Mehmet Oguz Gok, Jordyn D Svoboda, Keri-Lyn Kozul, Merima Forny, Jonathan R Friedman, and Natalie M Niemi

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Dual-localized PPTC7 limits mitophagy through proximal and dynamic interactions with BNIP3 and NIX, Lianjie Wei, Mehmet Oguz Gok, Jordyn D Svoboda, Keri-Lyn Kozul, Merima Forny, Jonathan R Friedman, and Natalie M Niemi

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Hemodynamics regulate spatiotemporal artery muscularization in the developing circle of Willis, Siyuan Cheng, Ivan Fan Xia, Renate Wanner, Javier Abello, Amber N Stratman, and Stefania Nicoli

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Phase Ib study of unesbulin (PTC596) plus dacarbazine for the treatment of locally recurrent, unresectable or metastatic, relapsed or refractory leiomyosarcoma, Brian A Van Tine, Matthew A Ingham, Steven Attia, Christian F Meyer, John D Baird, Esther Brooks-Asplund, Dhiren D'Silva, Ronald Kong, Anthony Mwatha, Kylie O'Keefe, Marla Weetall, Robert Spiegel, and Gary K Schwartz

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Attenuating midline thalamus bursting to mitigate absence epilepsy, Ping Dong, Konstantin Bakhurin, Yuhui Li, Mohamad A Mikati, Jianmin Cui, Warren M Grill, Henry H Yin, and Huanghe Yang

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Defining primary refractory large B-cell lymphoma, Allison M Bock, Brad S Kahl, and et al.

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DISPLACE study shows poor quality of transcranial Doppler ultrasound for stroke risk screening in sickle cell anemia, Kimberly A Davidow, Robin E Miller, Shannon M Phillips, Alyssa M Schlenz, Martina Mueller, Monica L Hulbert, Lewis L Hsu, Neha Bhasin, Robert J Adams, and Julie Kanter

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Progenitors of distinct lineages shape the diversity of mature type 2 conventional dendritic cells, Patrick Fernandes Rodrigues, Tihana Trsan, Grozdan Cvijetic, Darya Khantakova, Santosh K Panda, Zhaoyuan Liu, Florent Ginhoux, Marina Cella, and Marco Colonna

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The CNS relapse in T-cell lymphoma Index predicts CNS relapse in patients with T- and NK-cell lymphomas, Rahul S Bhansali, Neha Mehta-Shah, and et al.

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Unraveling facets of MECOM-associated syndrome: Somatic genetic rescue, clonal hematopoiesis, and phenotype expansion, Parvathy Venugopal, Kelly L Bolton, and et al.

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Where are we now with oncolytic viruses in melanoma and nonmelanoma skin malignancies?, George Nassief, Angela Anaeme, Karen Moussa, David Chen, and George Ansstas

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Cell-specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems, Jamie C Moffa, India N Bland, Jessica R Tooley, Vani Kalyanaraman, Monique Heitmeier, Meaghan C Creed, and Bryan A Copits

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Oral sebetralstat for on-demand treatment of hereditary angioedema attacks, Marc A Riedl, H James Wedner, and et al.

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SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis, Surbhi Chouhan, Dhivya Sridaran, Cody Weimholt, Jingqin Luo, Tiandao Li, Kiran Mahajan, Nupam P Mahajan, and et al.

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LEDoxy-SL: A placebo-controlled, double-blind, randomized, 24-month trial of six weeks of daily doxycycline plus hygiene-based essential care for reducing progression of filarial lymphedema in Sri Lanka, Thishan Channa Yahathugoda, Nirmitha Lalindi De Silva, Janaka Ruben, Sharmini Gunawardena, Mirani Vasanthamala Weerasooriya, John Horton, Philip Budge, Eric Ottesen, Sarah Mary Sullivan, Mariana Stephens, John Shen, Ute Klarmann-Schulz, Achim Hoerauf, Joseph Patrick Shott, and Charles Mackenzie

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O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer, Yi Zhang, Shuyan Zhou, Yan Kai, Ya-Qin Zhang, Changmin Peng, Zhuqing Li, Muhammad Jameel Mughal, Belmar Julie, Xiaoyan Zheng, Junfeng Ma, Cynthia X Ma, Min Shen, Matthew D Hall, Shunqiang Li, and Wenge Zhu

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Task and stimulus coding in the multiple-demand network, Sneha Shashidhara, Moataz Assem, Matthew F Glasser, and John Duncan

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A pan-cancer patient-derived xenograft histology image repository with genomic and pathologic annotations enables deep learning analysis, Brian S White, R Jay Mashl, Sherri R Davies, Ryan C Fields, Jacqueline L Mudd, Ramaswamy Govindan, Shunqiang Li, Li Ding, and et al.

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Assessment of patient-derived xenograft growth and antitumor activity: The NCI PDXNet consensus recommendations, Funda Meric-Bernstam, Ramaswamy Govinden, Li Ding, Ryan Fields, and et al.

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Baseline levels and longitudinal changes in plasma Aβ42/40 among Black and white individuals, Chengjie Xiong, Jingqin Luo, Rachel L Henson, Tammie L S Benzinger, Quoc Bui, Folasade Agboola, Elizabeth Grant, Emily N Gremminger, Krista L Moulder, Ganesh Babulal, Carlos Cruchaga, David M Holtzman, Randall J Bateman, John C Morris, Suzanne E Schindler, and et al.

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Identification of unique cell type responses in pancreatic islets to stress, Marlie M Maestas, Matthew Ishahak, Punn Augsornworawat, Daniel A Veronese-Paniagua, Kristina G Maxwell, Leonardo Velazco-Cruz, Erica Marquez, Jiameng Sun, Mira Shunkarova, Sarah E Gale, Fumihiko Urano, and Jeffrey R Millman

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Pathogenic variants in autism gene KATNAL2 cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics, Tyrone DeSpenza, Shujuan Zhao, Sheng Chih Jin, and et al.

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Pathogenic variants in autism gene KATNAL2 cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics, Tyrone DeSpenza, Shujuan Zhao, Sheng Chih Jin, and et al.

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[18F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue, Jelena Levi, Caroline Guglielmetti, and et al.

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A bistable inhibitory optoGPCR for multiplexed optogenetic control of neural circuits, Jonas Wietek, Bobbie J Brown, Bryan A Copits, and et al.

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Alcohol milestones and internalizing, externalizing, and executive function: Longitudinal and polygenic score associations, Sarah E Paul, David A A Baranger, Joshua J Jackson, Aaron J Gorelik, Alexander S Hatoum, Michael Strube, Andrey P Anokhin, Arpana Agrawal, Kathleen K Bucholz, Ryan Bogdan, and et al.

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A phase II trial of the WEE1 inhibitor adavosertib in SETD2-altered advanced solid tumor malignancies (NCI 10170), Edward Maldonado, Nikolaos A Trikalinos, and et al.

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Aqueous macrophages contribute to conserved CCL2 and CXCL10 gradients in uveitis, Joseph B Lin, Kathryn L Pepple, Christian Concepcion, Yulia Korshunova, Michael A Paley, Grace L Paley, Jennifer Laurent, Rajendra S Apte, and Lynn M Hassman

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A survey of availability and affordability of polypills for cardiovascular disease in selected countries, Gautam Satheesh, Bishal Gyawali, Marie France Chan Sun, Mark D Huffman, Amitava Banerjee, Pablo Perel, and Adrianna Murphy

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BAllC and BAllCools: Efficient formatting and operating for single-cell DNA methylation data, Wei Tian, Wubin Ding, Jiawei Shen, Daofeng Li, Ting Wang, and Joseph R Ecker

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Clinical Mycology Today: Emerging challenges and opportunities, Jessica Little, Adriana M Rauseo, Julio C Zuniga-Moya, Andrej Spec, Peter Pappas, John Perfect, Todd McCarthy, and Ilan S Schwartz

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Cognitive control training with domain-general response inhibition does not change children's brains or behavior, Keertana Ganesan, Abigail Thompson, Claire R Smid, Roser Cañigueral, Yongjing Li, Grace Revill, Vanessa Puetz, Boris C Bernhardt, Nico U F Dosenbach, Rogier Kievit, and Nikolaus Steinbeis

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Diagnostic efficacy and clinical impact of image-guided core needle biopsy of suspected vertebral osteomyelitis, Winston L Winkler, Ige A George, Sumanth Gandra, Jonathan C Baker, Anderanik Tomasian, Benjamin Northrup, Theodore L Vander Velde, Travis J Hillen, Chongliang Luo, Resten Imaoka, Gino M Dettorre, and Jack W Jennings

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Distinguishing recrudescence from reinfection in lymphatic filariasis, Young-Jun Choi, Kerstin Fischer, Aboulaye Méité, Benjamin G Koudou, Peter U Fischer, and Makedonka Mitreva

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Durable responses with mosunetuzumab in relapsed/refractory indolent and aggressive B-cell non-Hodgkin lymphomas: Extended follow-up of a phase I/II study, Lihua E Budde, Nancy L Bartlett, and et al.

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Epigenetic developmental mechanisms underlying sex differences in cancer, Joshua B. Rubin, Tamara Abou-Antoun, Joseph E. Ippolito, Lorida Llaci, Camryn T. Marquez, Jason P. Wong, and Lihua Yang

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Gene expression networks regulated by human personality, Coral Del Val, Elisa Díaz de la Guardia-Bolívar, Igor Zwir, Pashupati P Mishra, Alberto Mesa, Ramiro Salas, Guillermo F Poblete, Gabriel de Erausquin, Emma Raitoharju, Mika Kähönen, Olli Raitakari, Liisa Keltikangas-Järvinen, Terho Lehtimäki, and Claude Robert Cloninger

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Healthy dietary patterns are associated with exposure to environmental chemicals in a pregnancy cohort, Guoqi Yu, Ruijin Lu, Jiaxi Yang, Mohammad L Rahman, Ling-Jun Li, Dong D Wang, Qi Sun, Wei Wei Pang, Claire Guivarch, Anna Birukov, Jagteshwar Grewal, Zhen Chen, and Cuilin Zhang

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IL2 targeted to CD8+ T Cells promotes robust effector T-cell responses and potent antitumor immunity, Kelly D Moynihan, Hussein Sultan, Robert D Schreiber, and et al.

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Integrating multisector molecular characterization into personalized peptide vaccine design for patients with newly diagnosed glioblastoma, Tanner M Johanns, Elizabeth A R Garfinkle, Katherine E Miller, Alexandra J Livingstone, Kaleigh F Roberts, Lakshmi P Rao Venkata, Joshua L Dowling, Michael R Chicoine, Ralph G Dacey, Gregory J Zipfel, Albert H Kim, Elaine R Mardis, and Gavin P Dunn

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Matching-adjusted indirect comparison from the Lymphoma Epidemiology of Outcomes Consortium for Real World Evidence (LEO CReWE) study to a clinical trial of mosunetuzumab in relapsed or refractory follicular lymphoma, Matthew J. Maurer, Brad S. Kahl, and et al.

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Modulation of TMEM16B channel activity by the calcium-activated chloride channel regulator 4 (CLCA4) in human cells, Monica Sala-Rabanal, Zeynep Yurtsever, Kayla N Berry, Conor McClenaghan, Alyssa J Foy, Alex Hanson, Deborah F Steinberg, Jessica A Greven, Colin E Kluender, Jennifer M Alexander-Brett, Colin G Nichols, and Tom J Brett

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Momelotinib vs. ruxolitinib in myelofibrosis patient subgroups by baseline hemoglobin levels in the SIMPLIFY-1 trial, Vikas Gupta, Stephen Oh, and et al.

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Persistent transcriptional changes in cardiac adaptive immune cells following myocardial infarction: New evidence from the re-analysis of publicly available single cell and nuclei RNA-sequencing data sets, Natasha de Winter, Jiahui Ji, Amalia Sintou, Elvira Forte, Michael Lee, Michela Noseda, Aoxue Li, Andrew L Koenig, Kory J Lavine, Sikander Hayat, Nadia Rosenthal, Costanza Emanueli, Prashant K Srivastava, and Susanne Sattler

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Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis, Florian Gaertner, Marco Colonna, and et al.

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Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues, Sanjiv Neupane, Daniel B Williamson, Robyn A Roth, Carmen M Halabi, Robert S Haltiwanger, and Bernadette C Holdener

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Spinal calcifying pseudoneoplasms of the neuraxis: A case report and review of the literature, Ajay Chatrath, Mackenzie Lemieux, Rujvee P Patel, Kaleigh F Roberts, Sonika Dahiya, and Brenton Pennicooke

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Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor for Adults with Emotional Distress (SPEAC-2): Design and methods, Corina R Ronneberg, Thomas Kannampallil, and et al.

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Suicide in US preteens aged 8 to 12 years, 2001 to 2022, Donna A Ruch, Lisa M Horowitz, Jennifer L Hughes, Katherine Sarkisian, Joan L Luby, Cynthia A Fontanella, and Jeffrey A Bridge

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Survival disparities in rural versus urban patients with Pancreatic Neuroendocrine Tumor: A multi-institutional study from the US Neuroendocrine Tumor Study Group, Muhammad Bilal Mirza, Jordan J Baechle, Paula Marincola Smith, Mary Dillhoff, George Poultsides, Flavio G Rocha, Clifford S Cho, Emily R Winslow, Ryan C Fields, Shishir K Maithel, and Kamran Idrees

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Tumor-immune signatures of treatment resistance to brentuximab vedotin with ipilimumab and/or nivolumab in Hodgkin lymphoma, Edgar Gonzalez-Kozlova, Brad S Kahl, and et al.

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A pilot study of nintedanib in molecularly selected patients with advanced non-small cell lung cancer, Christine Auberle, Feng Gao, Mark Sloan, Daniel Morgensztern, Linda Winkler, Jeffrey P. Ward, Siddhartha Devarakonda, Timothy P. Rearden, Ramaswamy Govindan, and Saiama N. Waqar

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Extracorporeal membrane oxygenation for respiratory failure: A narrative review, John C Grotberg, Daniel Reynolds, and Bryan D Kraft

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Obesity is associated with muscle atrophy in rotator cuff tear, Simone D Herzberg, Robert H Brophy, Matthew V Smith, and et al.

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Python tooth-inspired fixation device for enhanced rotator cuff repair, Iden Kurtaliaj, Ethan D Hoppe, Yuxuan Huang, David Ju, Jacob A Sandler, Donghwan Yoon, and Guy M Genin

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Detection of early-stage NASH using non-invasive hyperpolarized 13C metabolic imaging, Cornelius von Morze, Tyler Blazey, Ashley Shaw, William M Spees, Kooresh I Shoghi, and Michael A Ohliger

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Examining associations between smartphone use and clinical severity in frontotemporal dementia: Proof-of-concept study, Emily W Paolillo, Nupur Ghoshal, and et al.

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Airy-beam holographic sonogenetics for advancing neuromodulation precision and flexibility, Zhongtao Hu, Yaoheng Yang, Leqi Yang, Yan Gong, Chinwendu Chukwu, Dezhuang Ye, Yimei Yue, Jinyun Yuan, Alexxai V Kravitz, and Hong Chen

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A shared group of bacterial taxa in the duodenal microbiota of undernourished Pakistani children with environmental enteric dysfunction, Najeeha T Iqbal, Robert Y Chen, Nicholas W Griffin, Matthew C Hibberd, Michael J Barratt, Jeffrey I Gordon, and et al.

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Injury-induced Foxm1 expression in the mouse kidney drives epithelial proliferation by a cyclin F-dependent mechanism, Megan L. Noonan, Yoshiharu Muto, Yasuhiro Yoshimura, Aidan Leckie-Harre, Haojia Wu, Vladimir V. Kalinichenko, Benjamin D. Humphreys, and Monica Chang-Panesso

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Myeloablative vs nonmyeloablative consolidation for primary central nervous system lymphoma: Results of Alliance 51101, Tracy T Batchelor, Brad S Kahl, Nancy L Bartlett, Nina Wagner-Johnston, and et al.

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The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study, Zachary Shaffer, Roberto Romero, Adi L Tarca, Jose Galaz, Marcia Arenas-Hernandez, Dereje W Gudicha, Tinnakorn Chaiworapongsa, Eunjung Jung, Manaphat Suksai, Kevin R Theis, and Nardhy Gomez-Lopez

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Clinical prediction for surgical versus nonsurgical interventions in patients with vertebral osteomyelitis and discitis, Jennifer Lee, Miguel A. Ruiz-Cardozo, Rujvee P. Patel, Saad Javeed, Raj Swaroop Lavadi, Catherine Newsom-Stewart, Anton Alyakin, Camilo A. Molina, Nitin Agarwal, Wilson Z. Ray, Michele Santacatterina, and Brenton H. Pennicooke

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Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia, Shamsuddin A Bhuiyan, Lite Yang, Lisa A McIlvried, Bryan A Copits, Zachariah Bertels, John S Del Rosario, Allie J Widman, Richard A Slivicki, Jiwon Yi, Robert W Gereau Iv, and et al.

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Noninvasive assessment of the lung inflammation-fibrosis axis by targeted imaging of CMKLR1, Philip Z Mannes, Taylor S Adams, Samaneh Farsijani, Clayton E Barnes, Joseph D Latoche, Kathryn E Day, Jessie R Nedrow, Farida Ahangari, Naftali Kaminski, Janet S Lee, and Sina Tavakoli

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Antibiotic dispensing practices among informal healthcare providers in low-income and middle-income countries: A scoping review protocol, Meera Tandan, Poshan Thapa, Buna Bhandari, Sumanth Gandra, Diwash Timalsina, Shweta Bohora, Swostika Thapaliya, Anupama Bhusal, Genevieve C Gore, Surbhi Sheokand, Prachi Shukla, Chandrashekhar Joshi, Nitin Mudgal, Madhukar Pai, and Giorgia Sulis

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Impact of cognitive impairment on driving behaviour and route choices of older drivers: A real-world driving study, Reihaneh Derafshi, Ganesh M Babulal, and Sayeh Bayat

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Protein restriction slows the development and progression of pathology in a mouse model of Alzheimer's disease, Reji Babygirija, Natalie M Niemi, and et al.

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Structural basis for hyperpolarization-dependent opening of human HCN1 channel, Verena Burtscher, Jonathan Mount, Jian Huang, John Cowgill, Yongchang Chang, Kathleen Bickel, Jianhan Chen, Peng Yuan, and Baron Chanda

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Cancer-associated histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation, Benjamin A Nacev, Benjamin A Garcia, and et al.

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Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase, Roberto Efraín Díaz, Andrew K Ecker, Galen J Correy, Pooja Asthana, Iris D Young, Bryan Faust, Michael C Thompson, Ian B Seiple, Steven Van Dyken, Richard M Locksley, and James S Fraser

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A randomized, double-blind, phase 3 safety and efficacy study of ridinilazole versus vancomycin for treatment of Clostridioides difficile infection: Clinical outcomes with microbiome and metabolome correlates of response, Pablo C Okhuysen, Erik R Dubberke, and et al.

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Through the Cat-Map gateway: A brief history of cataract genetics, Alan Shiels

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Comorbid neurotrauma increases neurodegenerative-relevant cognitive, motor, and autonomic dysfunction in patients with rapid eye movement sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium, Jonathan E Elliott, Jennifer McLeland, Yo-El S Ju, and et al.

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A systematic review and meta-analysis, investigating dose and time of fluvoxamine treatment efficacy for COVID-19 clinical deterioration, death, and long-COVID complications, Mani Iyer Prasanth, Dhammika Leshan Wannigama, Angela Michelle Reiersen, Premrutai Thitilertdecha, Anchalee Prasansuklab, Tewin Tencomnao, Sirikalaya Brimson, and James Michael Brimson

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Inhibitory roles of apolipoprotein E Christchurch astrocytes in curbing tau propagation using human pluripotent stem cell-derived models, Rei Murakami, Hirotaka Watanabe, Hideko Hashimoto, Mayu Kashiwagi-Hakozaki, Tadafumi Hashimoto, Celeste M. Karch, Takeshi Iwatsubo, Hideyuki Okano, and Dominantly Inherited Alzheimer Network (DIAN)

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An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination, Kia M Barclay, Nora Abduljawad, Min Woo Kim, Lu Zhou, Jin Yang, Justin Rustenhoven, Jose A Mazzitelli, Leon C D Smyth, Dvita Kapadia, Simone Brioschi, Wandy Beatty, JinChao Hou, Naresha Saligrama, Marco Colonna, Jonathan Kipnis, Qingyun Li, and et al.

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Limited nerve regeneration across acellular nerve allografts (ANAs) coincides with changes in blood vessel morphology and the development of a pro-inflammatory microenvironment, Jesús A Acevedo Cintrón, Daniel A Hunter, Lauren Schellhardt, Deng Pan, Susan E Mackinnon, and Matthew D Wood

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Outcomes of subsequent antilymphoma therapies after second-line axicabtagene ciloleucel or standard of care in ZUMA-7, Armin Ghobadi and et al.

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Tenovin-1, a selective SIRT1/2 inhibitor, attenuates high-fat diet-induced hepatic fibrosis via Inhibition of HSC activation in ZDF rats, Swati Sharma, Sreevarsha Gali, Amit Kundu, Jae Hyeon Park, Jae-Sung Kim, and Hyung Sik Kim

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Cis-regulatory evolution of the recently expanded Ly49 gene family, Changxu Fan, Xiaoyun Xing, Samuel J H Murphy, Jennifer Poursine-Laurent, Heather Schmidt, Bijal A Parikh, Jeesang Yoon, Mayank N K Choudhary, Naresha Saligrama, Sytse J Piersma, Wayne M Yokoyama, and Ting Wang

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The burden of cardiovascular disease attributable to hypertension in Nigeria: A modelling study using summary-level data, Adedayo E Ojo, Dike B Ojji, Diederick E Grobbee, Mark D Huffman, and Sanne A E Peters

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Evaluation of copanlisib in combination with eribulin in triple-negative breast cancer patient-derived xenograft models, Zhanfang Guo, Jingqin Luo, R Jay Mashl, Jeremy Hoog, Piyush Maiti, Nikki Fettig, Sherri R Davies, Rebecca Aft, Jason M Held, Ramaswamy Govindan, Li Ding, Shunqiang Li, Cornelius von Morze, Kooresh I Shoghi, Cynthia X Ma, and et al.

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TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice, Mario Ruiz Pérez, Kodi Ravichandran, and et al.

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COMPANION-002 a clinical trial of investigational drug CTX-009 plus paclitaxel vs paclitaxel in second line advanced BTC, Nilofer Azad, Olivia Aranha, and et al.

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Cannabis, tobacco use, and COVID-19 outcomes, Nicholas B Griffith, Timothy B Baker, Brendan T Heiden, Nina Smock, Giang Pham, Jingling Chen, Justin Yu, James Reddy, Albert M Lai, Eric Hogue, Laura J Bierut, and Li-Shiun Chen

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Generalized genetic liability to substance use disorders, Alex P. Miller, Ryan Bogdan, Arpana Agrawal, and Alexander S. Hatoum

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Glutamatergic supramammillary nucleus neurons respond to threatening stressors and promote active coping, Abraham Escobedo, Salli-Ann Holloway, Megan Votoupal, Aaron L Cone, Hannah Skelton, Alex A Legaria, Imeh Ndiokho, Tasheia Floyd, Alexxai V Kravitz, Michael R Bruchas, and Aaron J Norris

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Hexamerization: Explaining the original sin of IgG-mediated complement activation in acute lung injury, Hrishikesh S. Kulkarni

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Neutrophils and galectin-3 defend mice from lethal bacterial infection and humans from acute respiratory failure, Sudipta Das, Janet S Lee, and et al.

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Phantasus, a web application for visual and interactive gene expression analysis, Maksim Kleverov, Daria Zenkova, Vladislav Kamenev, Margarita Sablina, Maxim N Artyomov, and Alexey A Sergushichev

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Secure messaging and telephone use for clinician-to-clinician communication, Sunny S Lou, Daphne Lew, Laura R Baratta, Elise Eiden, Christine A Sinsky, and Thomas Kannampallil

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Severe pediatric neurological manifestations with SARS-CoV-2 or MIS-C hospitalization and new morbidity, Conall Francoeur, Kristin P Guilliams, Shannon C Agner, and et al.

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aEEG in the first 3 days after extremely preterm delivery relates to neurodevelopmental outcomes, Roberta Pineda, Zachary Vesoulis, Nathalie El Ters, and Amit Mathur

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A microbiota-directed complementary food intervention in 12-18-month-old Bangladeshi children improves linear growth, Ishita Mostafa, Matthew C Hibberd, Steven J Hartman, Md Hasan Hafizur Rahman, Mustafa Mahfuz, S M Tafsir Hasan, Per Ashorn, Michael J Barratt, Tahmeed Ahmed, and Jeffrey I Gordon

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Anomalous left superior vena cava predisposing to recurrent brain abscesses: A case report and review of the literature, Adnan Shaik, Karan Joseph, Rahim Abo Kasem, Angela Downes, and Muhammed B. Janjua