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Submissions from 2022

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Bi-allelic CAMSAP1 variants cause a clinically recognizable neuronal migration disorder, Reham Khalaf-Nazzal, Jennifer L Griffith, Joseph R Walsh, Amber Neilson, Evguenia Kouranova, Xiaoxia Cui, David T Curiel, and et al.

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Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes, Chia-Jung Lee, Ting-Huei Chen, Aylwin Ming Wee Lim, Chien-Ching Chang, Jia-Jyun Sie, Pei-Lung Chen, Su-Wei Chang, Shang-Jung Wu, Chia-Lin Hsu, Ai-Ru Hsieh, Wei-Shiung Yang, and Cathy S J Fann

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Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter, Michael Lim, George Ansstas, and et al.

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Proteogenomic markers of chemotherapy resistance and response in triple-negative breast cancer, Meenakshi Anurag, Shunqiang Li, Ian S Hagemann, Jeremy Hoog, Foluso O Ademuyiwa, and et al.

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The 5-hydroxymethylcytosine landscape of prostate cancer, Martin Sjöström, Nupam P Mahajan, Christopher A Maher, and et al.

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Accounting for the growth of observation stays in the assessment of Medicare's Hospital Readmissions Reduction Program, Amber K Sabbatini, Karen E Joynt-Maddox, Joshua M Liao, Anirban Basu, Canada Parrish, William Kreuter, and Brad Wright

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A comparison of methods to harmonize cortical thickness measurements across scanners and sites, Delin Sun, Evan Gordon, and et al.

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American Cochlear Implant Alliance Task Force guidelines for clinical assessment and management of adult cochlear implantation for single-sided deafness, Margaret T. Dillon, Armine Kocharyan, Ghazal S. Daher, Matthew L. Carlson, William H. Shapiro, Hillary A. Snapp, and Jill B. Firszt

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Amyloid-β and tau deposition influences cognitive and functional decline in Down syndrome, Monika Grigorova, Beau Ances, and et al.

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An assessment of pediatric residency applicant perceptions of "Fit" during the virtual interview era, Jason D. Vadhan, Jorge G. Zarate Rodriguez, Michael Wallendorf, Michael M. Awad, and Andrew J. White

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A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication, Ghjuvan'Ghjacumu Shackleford, Yo Sasaki, and et al.

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A phase I first-in-human study of ABBV-383, a B-cell maturation antigen × CD3 bispecific T-cell redirecting antibody, in patients with relapsed/refractory multiple myeloma, Anita D'Souza, Ravi Vij, and et al.

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A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond, Marcus S Noel, Semmie Kim, Marion L Hartley, Steve Wong, Vincent J Picozzi, Harry Staszewski, Dae Won Kim, Jan M Van Tornout, Philip Agop Philip, Vincent Chung, Allyson J Ocean, and Andrea Wang-Gillam

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A report of 2 cases of the use of the Inari FlowTriever System in the treatment of pulmonary embolism, Richard Pham, Alexander Sasha Ushinsky, Naganathan Mani, and Pavan K Kavali

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Ascertainment of vaccination status by self-report versus source documentation: Impact on measuring COVID-19 vaccine effectiveness, Meagan Stephenson, Jennie H Kwon, and et al

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Assessment of infectious diseases risks from dental aerosols in real-world settings, Shruti Choudhary, Tracey Bach, Meghan A Wallace, Daniel C Stoeckel, Martin H Thornhill, Peter B Lockhart, Jennie H Kwon, Stephen Y Liang, Carey-Ann D Burnham, Pratim Biswas, Heidi M Steinkamp, and Michael J Durkin

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Association of noncontrast computed tomography and perfusion modalities with outcomes in patients undergoing late-window stroke thrombectomy, Guilherme B F Porto, Joshua Osbun, and et al.

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Associations between transcranial Doppler vasospasm and clinical outcomes after aneurysmal subarachnoid hemorrhage: A retrospective observational study, Abhijit V. Lele, Rafael Wabl, Sarah Wahlster, Jade Keen, Andrew M. Walters, Christine T. Fong, Vasu B. Dhulipala, Umeshkumar Athiraman, Anne Moore, Monica S. Vavilala, Louis J. Kim, and Michael R. Levitt

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Better operating room ventilation as determined by a novel ventilation index is associated with lower rates of surgical site infections, Bernard Surial, Andrew Atkinson, Rüdiger Külpmann, Arnold Brunner, Kurt Hildebrand, Benoît Sicre, Nicolas Troillet, Andreas Widmer, Eveline Rolli, Judith Maag, and Jonas Marschall

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Clinical characteristics of children with cerebral injury preceding treatment of diabetic ketoacidosis, Nicole S Glaser, Kimberly S Quayle, and et al.

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Comparison of indirect fungal diagnostic tests in patients with proven histoplasmosis, Gayathri Krishnan, Margaret Power, J Ryan Bariola, and Ryan Dare

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Covariance-based vs. correlation-based functional connectivity dissociates healthy aging from Alzheimer disease, Jeremy F. Strain, Matthew R. Brier, Aaron Tanenbaum, Brian A. Gordon, John E. McCarthy, Aylin Dincer, Daniel S. Marcus, Richard J. Perrin, John C. Morris, Tammie L. S. Benzinger, Randall J. Bateman, Beau M. Ances, Abraham Z. Snyder, and et al.

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Engineering diverse fatty acid compositions of phospholipids in Escherichia coli, Wenqin Bai, Winston E Anthony, Christopher J Hartline, Shaojie Wang, Bin Wang, Jie Ning, Fong-Fu Hsu, Gautam Dantas, and Fuzhong Zhang

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Facial paresis as the first sign in atypical facioscapulohumeral muscular dystrophy, Nneoma S. Wamkpah and John J. Chi

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Guidance for the diagnosis and treatment of hypolipidemia disorders, Cindy Bredefeld, Nicholas O Davidson, and et al.

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Hospital trajectories and early predictors of clinical outcomes differ between SARS-CoV-2 and influenza pneumonia, Patrick G Lyons, Aaloke Mody, Alice Bewley, Katherine Dittman, Aisling Doyle, Samuel L Windham, Tej M Patel, Bharat Neelam Raju, Matthew Keller, Andrew P Michelson, Thomas Kannampallil, Elvin H Geng, Pratik Sinha, and et al.

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Human immunodeficiency virus pre-exposure prophylaxis knowledge, attitudes, and self-efficacy among family planning providers in the Southern United States: Bridging the gap in provider training, Aditi Ramakrishnan, Jessica M Sales, Micah McCumber, Leah Powell, and Anandi N Sheth

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Implementation of telemedicine infectious diseases consultation in a rural hospital using the Active Implementation Framework, Jason P Burnham, Stephanie A Fritz, and Graham A Colditz

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Infectious complications of abortion, L. Lewis Wall and Awol Yemane

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Inositol phosphorylceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates, F Matthew Kuhlmann, Phillip N Key, Suzanne M Hickerson, John Turk, Fong-Fu Hsu, and Stephen M Beverley

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Inositol phosphorylceramide synthase null Leishmania are viable and virulent in animal infections where salvage of host sphingomyelin predominates, F Matthew Kuhlmann, Phillip N Key, Suzanne M Hickerson, John Turk, Fong-Fu Hsu, and Stephen M Beverley

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International consensus guidelines for adjuvant radiation therapy for bladder cancer after radical cystectomy: Update from an IBIS workgroup, Flor Verghote, Paul Sargos, John P Christodouleas, Vedang Murthy, Brian C Baumann, Piet Dirix, Charlien Berghen, Leen Paelinck, Tom Vercauteren, and Valérie Fonteyne

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Local failure events in prostate cancer treated with radiotherapy: A pooled analysis of 18 randomized trials from the Meta-analysis of Randomized Trials in Cancer of the Prostate Consortium (LEVIATHAN), Ting Martin Ma, Jeff M Michalski, and et al.

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Manufacturing-dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development, Neeltje Steeghs, Haeseong Park, and et al.

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N-terminal acetylation and arginylation of actin determines the architecture and assembly rate of linear and branched actin networks, Samantha M Chin, Tomoyuki Hatano, Lavanya Sivashanmugam, Andrejus Suchenko, Anna S Kashina, Mohan K Balasubramanian, and Silvia Jansen

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Peroxisomal regulation of energy homeostasis: Effect on obesity and related metabolic disorders, Brian Kleiboeker and Irfan J Lodhi

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Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1L, Cuige Zhu, Mari Iwase, Ziqian Li, Faliang Wang, Annabel Quinet, Alessandro Vindigni, and Jieya Shao

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Quantification of sulcal emergence timing and its variability in early fetal life: Hemispheric asymmetry and sex difference, Hyuk JIn Yun, Hyun Ju Lee, Joo Young Lee, Tomo Tarui, Caitlin K. Rollins, Cynthia M. Ortinau, Henry A. Feldman, P. Ellen Grant, and Kiho Im

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Quantitative tumor depth determination using dual wavelength excitation fluorescence, Christine M. O'Brien, Kevin W. Bishop, Haini Zhang, Xiao Xu, Leo Shmuylovich, Elizabeth Conley, Karen Nwosu, Kathleen Duncan, Suman B. Mondal, and Gail Sudlow

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Real-world evidence supporting Tandem Control-IQ hybrid closed-loop success in the Medicare and Medicaid type 1 and type 2 diabetes populations, Gregory P Forlenza, Anders L Carlson, Rodolfo J Galindo, Davida F Kruger, Carol J Levy, Janet B McGill, Guillermo Umpierrez, and Grazia Aleppo

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Real-world utilization and outcomes of systemic therapy among patients with advanced or recurrent endometrial cancer in the United States, Jinan Liu, Bruno Emond, Eric M Maiese, Marie-Hélène Lafeuille, Patrick Lefebvre, Isabelle Ghelerter, Caterina Wu, Jean A Hurteau, and Premal H Thaker

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Self-care management of bothersome symptoms as recommended by clinicians for patients with a chronic condition: A Delphi study, Heleen Westland, Shayleigh Dickson Page, Michelle van Rijn, Subhash Aryal, Kenneth E Freedland, Christopher Lee, Anna Strömberg, Ercole Vellone, Douglas J Wiebe, Tiny Jaarsma, and Barbara Riegel

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The programmed death-1 signaling axis modulates inflammation and LV structure/function in a stress-induced cardiomyopathy model, Tomohiro Hayashi, Sajal K Tiwary, Kory J Lavine, Sandeep Acharya, Michael Brent, Luigi Adamo, Attila Kovacs, and Douglas L Mann

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To calibrate or not to calibrate? A methodological dilemma in experimental pain research, Waclaw M Adamczyk, Tibor M Szikszay, Hadas Nahman-Averbuch, Jacek Skalski, Jakub Nastaj, Philip Gouverneur, and Kerstin Luedtke

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Transgenic force sensors and software to measure force transmission across the mammalian nuclear envelope in vivo, Kelli D Fenelon, Evan Thomas, Mohammad Samani, Min Zhu, Hirotaka Tao, Yu Sun, Helen McNeill, and Sevan Hopyan

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TRIM-NHL protein, NHL-2, modulates cell fate choices in the C. elegans germ line, John L. Brenner, Erin M. Jyo, Ariz Mohammad, Paul Fox, Vovanti Jones, Elaine Mardis, Tim Schedl, and Eleanor M. Maine

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Upper limb nerve transfer surgery in patients with tetraplegia, Saad Javeed, Christopher F Dibble, Jacob K Greenberg, Justin K Zhang, Jawad M Khalifeh, Yikyung Park, Thomas J Wilson, Eric L Zager, Amir H Faraji, Mark A Mahan, Lynda J Yang, Rajiv Midha, Neringa Juknis, and Wilson Z Ray

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Diagnosis and management of functional tic-like phenomena, Irene A Malaty, Seonaid Anderson, Shannon M Bennett, Cathy L Budman, Barbara J Coffey, Keith A Coffman, Erica Greenberg, Joseph F McGuire, Kirsten R Müller-Vahl, Michael S Okun, Julio Quezada, Amy Robichaux-Viehoever, and Kevin J Black

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High-speed, scanned laser structuring of multi-layered eco/bioresorbable materials for advanced electronic systems, Quansan Yang, Yameng Xu, Ying Yan, Wilson Z Ray, Mitchell A Pet, Matthew R MacEwan, and et al.

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Identification of novel genes and proteoforms in Angiostrongylus costaricensis through a proteogenomic approach, Esdras Matheus Gomes da Silva, Karina Mastropasqua Rebello, Young-Jun Choi, Vitor Gregorio, Alexandre Rossi Paschoal, Makedonka Mitreva, James H McKerrow, Ana Gisele da Costa Neves-Ferreira, and Fabio Passetti

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Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis, Yoshiharu Muto, Eryn E Dixon, Yasuhiro Yoshimura, Haojia Wu, Kohei Omachi, Nicolas Ledru, Parker C Wilson, Jeffrey H Miner, Benjamin D Humphreys, and et al.

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Myocardial infarction size as an independent predictor of intramyocardial haemorrhage in acute reperfused myocardial ischaemic rats, Rui Xia, Tong Zhu, Yu Zhang, Bo He, Yushu Chen, Lei Wang, Yang Zhou, Jichun Liao, Jie Zheng, Yongmei Li, Fajin Lv, and Fabao Gao

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Discovery and characterization of potent, efficacious, orally available antimalarial Plasmepsin X inhibitors and preclinical safety assessment of UCB7362, Martin A Lowe, Daniel E Goldberg, and et al.

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Genetic addiction risk and psychological profiling analyses for "preaddiction" severity index, Kenneth Blum, Mark S Gold, and et al.

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Mindfulness training for depressed older adults using smartphone technology: Protocol for a fully remote precision clinical trial, Abigail Schweiger, Thomas L Rodebaugh, Eric J Lenze, Katie Keenoy, Jason Hassenstab, Jeanne Kloeckner, Torie R Gettinger, and Ginger E Nicol

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Risk factors and treatment strategy for retinal vascular occlusive diseases, Ryo Terao, Ryosuke Fujino, and Tazbir Ahmed

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Comparison of metagenomic sequencing and the NanoString nCounter analysis system for the characterization of bacterial and viral communities in vaginal samples, Todd N Wylie, Jane Schrimpf, Haley Gula, Brandi N Herter, and Kristine M Wylie

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Emergence of compensatory mutations reveals the importance of electrostatic interactions between HIV-1 integrase and genomic RNA, Christian Shema Mugisha, Tung Dinh, Abhishek Kumar, Kasyap Tenneti, Jenna E Eschbach, Keanu Davis, Robert Gifford, Mamuka Kvaratskhelia, and Sebla B Kutluay

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Enteric pathogen testing importance for children with acute gastroenteritis: A modified Delphi study, Gillian A M Tarr, Drew J Persson, Phillip I Tarr, and Stephen B Freedman

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Epidemiology of plasmid lineages mediating the spread of extended-spectrum beta-lactamases among clinical Escherichia coli, Bejan Mahmud, Meghan A Wallace, Kimberly A Reske, Kelly Alvarado, Carol E Muenks, David A Rasmussen, Carey-Ann D Burnham, Cristina Lanzas, Erik R Dubberke, and Gautam Dantas

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Self-renewal of macrophages: Tumor-released factors and signaling pathways, Serena Filiberti, Mariapia Russo, Silvia Lonardi, Mattia Bugatti, William Vermi, Cathy Tournier, and Emanuele Giurisato

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Discovery of a novel genomic alteration that renders leukemic cells resistant to CD19-targeted immunotherapies, Armin Ghobadi, Jack H Landmann, Alun Carter, Matthew L Cooper, Mehmet Emrah Selli, Jufang Chang, Christopher A Miller, Francesca Ferraro, David Y Chen, Amanda M Smith, Taylor A LaValle, Eric J Duncavage, Nathan Singh, and et al.

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Human neutrophil development and functionality are enabled in a humanized mouse model, Yunjiang Zheng, Esen Sefik, John Astle, Kutay Karatepe, Hasan H Öz, Angel G Solis, Ruaidhrí Jackson, Hongbo R Luo, Emanuela M Bruscia, Stephanie Halene, Liang Shan, and Richard A Flavell

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Novel chelating agents for zirconium-89-positron emission tomography (PET) imaging: Synthesis, DFT calculation, radiolabeling, and in vitro and in vivo complex stability, Chi Soo Kang, Shuyuan Zhang, Haixing Wang, Yujie Liu, Siyuan Ren, Yanda Chen, Jingbai Li, Nilantha Bandara, Andrey Yu Rogachev, Buck E Rogers, and Hyun-Soon Chong

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Pooled image-base screening of mitochondria with microraft isolation distinguishes pathogenic Mitofusin 2 mutations, Alex L Yenkin, John C Bramley, Colin L Kremitzki, Jason E Waligorski, Mariel J Liebeskind, Xinyuan E Xu, Vinay D Chandrasekaran, Maria A Vakaki, Graham W Bachman, Robi D Mitra, Jeffrey D Milbrandt, and William J Buchser

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Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics, Taylor M Nye, Hasan Tükenmez, Pardeep Singh, Ana L Flores-Mireles, Chloe L P Obernuefemann, Jerome S Pinkner, Souvik Sarkar, Mari Bonde, Anders E G Lindgren, Karen W Dodson, Jörgen Johansson, Fredrik Almqvist, Michael G Caparon, and Scott J Hultgren

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Somatic mutations in FAT cadherin family members constitute an underrecognized subtype of colorectal adenocarcinoma with unique clinicopathologic features, Liang-Li Wang, Wei Zheng, Xiu-Li Liu, and Feng Yin

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The impact of TSC-1 and -2 mutations on response to therapy in malignant PEComa: A multicenter retrospective analysis, Lawrence Liu, Nikhil Grandhi, Yang Lyu, Xiao Zhang, Jingqin Luo, Mia Weiss, Brian Van Tine, Angela C Hirbe, and et al.

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Personalized ctDNA micro-panels can monitor and predict clinical outcomes for patients with triple-negative breast cancer, Erica K Barnell, Bryan Fisk, Zachary L Skidmore, Kelsy C Cotto, Anamika Basu, Aparna Anand, Megan M Richters, Jingqin Luo, Catrina Fronick, Meenakshi Anurag, Robert Fulton, Matthew J Ellis, Obi L Griffith, Malachi Griffith, and Foluso O Ademuyiwa

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A randomized feasibility pilot-study of intravenous and subcutaneous administration of ketamine to prevent postpartum depression after planned cesarean delivery under neuraxial anesthesia, David Thomas Monks, Arvind Palanisamy, Danish Jaffer, Preet Mohinder Singh, Ebony Carter, and Shannon Lenze

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A comparison of bioimpedance analysis vs. dual x-ray absorptiometry for body composition assessment in postpartum women and non-postpartum controls, Valene Garr Barry, Samantha L Martin, Paula Chandler-Laney, Ebony B Carter, and Camille S Worthington

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Complete genome sequence of the uropathogenic methicillin-resistant Staphylococcus aureus strain MRSA-1369, Hasan Tükenmez, Taylor M Nye, Mari Bonde, Michael G Caparon, Fredrik Almqvist, Scott J Hultgren, and Jörgen Johansson

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Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults, Katrina L Kalantar, Pratik Sinha, and et al.

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Can the "female protective effect" liability threshold model explain sex differences in autism spectrum disorder?, Joseph D Dougherty, Natasha Marrus, Susan E Maloney, Benjamin Yip, Sven Sandin, Tychele N Turner, Din Selmanovic, Kristen L Kroll, David H Gutmann, John N Constantino, and Lauren A Weiss

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Semi-automated assembly of high-quality diploid human reference genomes, Erich D Jarvis, Sarah Cody, Robert S Fulton, Lucinda L Fulton, Daofeng Li, Tina Lindsay, Nathan O Stitziel, Ting Wang, and et al.

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Activity-dependent translation dynamically alters the proteome of the perisynaptic astrocyte process, Darshan Sapkota, Kristina Sakers, Kayla R Nygaard, Yating Liu, Sarah K Koester, Stuart B Fass, Allison M Lake, Rohan Khazanchi, Susan E Maloney, Joseph D Dougherty, and et al.

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Prenatal exposure to maternal social disadvantage and psychosocial stress and neonatal white matter connectivity at birth, Rachel E Lean, Christopher D Smyser, Rebecca G Brady, Regina L Triplett, Sydney Kaplan, Jeanette K Kenley, Joshua S Shimony, Tara A Smyser, J Phillip Miller, Deanna M Barch, Joan L Luby, Barbara B Warner, and Cynthia E Rogers

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Cellular landscaping of COVID-19 and gynaecological cancers: An infrequent correlation, Rahul Bhattacharjee, Debanjan Das, Radheka Bhadhuri, Srija Chakraborty, Tanima Dey, Rupam Buragohain, Asim Nath, Kartik Muduli, Pranjan Barman, and Rohit Gundamaraju

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Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep, Hemanth R. Nelvagal, Sophie H. Wang, Elizabeth M. Eultgen, Keigo Takashash, Steven Q. Le, Rachel Nesbitt, Joshua T. Dearborn, Patricia I. Dickson, Mark S. Sands, Jonathan D. Cooper, and et al.

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IL-1β-dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction, Wenbin Yang, Daniel Kreisel, and et al.

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HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia, Qianze Dong, Nick Borcherding, and et al.

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BOLD cofluctuation 'events' are predicted from static functional connectivity, Zach Ladwig, Benjamin A. Seitzman, Ally Dworetsky, Yuhua Yu, Babatunde Adeyemo, Derek M. Smith, Steven E. Petersen, and Caterina Gratton

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Impact of the COVID-19 pandemic on the implementation of mobile health to improve the uptake of hydroxyurea in patients with sickle cell disease: Mixed methods study, Sherif M Badawy, Lisa DiMartino, Donald Brambilla, Lisa Klesges, Ana Baumann, Ebony Burns, Terri DeMartino, Sara Jacobs, Hamda Khan, Chinonyelum Nwosu, Nirmish Shah, Jane S Hankins, and Sickle Cell Disease Implementation Consortium

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Predicting postoperative troponin in patients undergoing elective hip or knee arthroplasty: A comparison of five cardiac risk prediction tools, Merih T Tesfazghi, Anne R Bass, Noor Al-Hammadi, Scott C Woller, Scott M Stevens, Charles S Eby, Mitchell G Scott, Lindsey Snyder, Troy S Wildes, and Brian F Gage

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Trial of Ultrasound guided carpal tunnel release versus Traditional Open Release (TUTOR), Kyle R. Eberlin, Christopher J. Dy, Mark D. Fischer, James L. Gluck, F. Thomas D. Kaplan, Thomas J. McDonald, Larry E. Miller, Alexander Palmer, Marc E. Walker, and James F. Watt

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Clinical and molecular response to tebentafusp in previously treated patients with metastatic uveal melanoma: A phase 2 trial, Richard D Carvajal, Leonel Hernandez-Aya, and et al.

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Amyloid β, lipid metabolism, basal cholinergic system, and therapeutics in Alzheimer's disease, Victoria Campos-Peña, Pavel Pichardo-Rojas, Talía Sánchez-Barbosa, Emma Ortíz-Islas, Citlali Ekaterina Rodríguez-Pérez, Pedro Montes, Gerardo Ramos-Palacios, Daniela Silva-Adaya, Rafael Valencia-Quintana, Jorge Francisco Cerna-Cortes, and Danira Toral-Rios

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Association of α-klotho with subclinical carotid atherosclerosis in subjects with type 1 diabetes mellitus, Esmeralda Castelblanco, Marta Hernández, Nuria Alonso, Aina Ribes-Betriu, Jordi Real, Minerva Granado-Casas, Joana Rossell, Marina Idalia Rojo-López, Adriana Silvia Dusso, Josep Julve, and Didac Mauricio

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Collaborative quality improvement strategy in secondary prevention of cardiovascular disease in India: Findings from a multi-stakeholder, qualitative study using Consolidated Framework for Implementation Research (CFIR), Kavita Singh, Mark D. Huffman, Leslie C M Johnson, Nikhil Tandon, Dorairaj Prabhakaran, and Emily Mendenhall

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Whole genome sequence analysis of blood lipid levels in >66,000 individuals, Margaret Sunitha Selvaraj, Lisa de Las Fuentes, Susan K. Dutcher, and et al.

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Blood culture utilization practices among febrile and/or hypothermic inpatients, Kap Sum Foong, Satish Munigala, Stephanie Kern-Allely, and David K Warren

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Occupational characteristics associated with SARS-CoV-2 infection in the UK Biobank during August-November 2020: A cohort study, Elizabeth L Yanik, Bradley A Evanoff, Ann Marie Dale, Yinjiao Ma, and Karen E Walker-Bone

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Cellular sources and neuroprotective roles of interleukin-10 in the facial motor nucleus after axotomy, Elizabeth M Runge, Deborah O Setter, Abhirami K Iyer, Eric J Regele, Felicia M Kennedy, Virginia M Sanders, and Kathryn J Jones

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Global variation in isolated posterior cruciate ligament reconstruction, Derrick M Knapik, Varun Gopinatth, Garrett R Jackson, Jorge Chahla, Matthew V Smith, Matthew J Matava, and Robert H Brophy

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Why tic severity changes from then to now and from here to there, Ann M Iverson and Kevin J Black

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A bioresorbable peripheral nerve stimulator for electronic pain block, Geumbee Lee, Emily Ray, Sabrina Genovese, Ying Yan, Arman Odabas, Umang Khandpur, Wilson Z Ray, Matthew R MacEwan, and et al.

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Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond, Nathan Gaddis, Arpana Agrawal, Paul W Jeffries, Kathleen Bucholz, Elliot C Nelson, Laura Bierut, and et al.

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Spontaneous activity patterns in human motor cortex replay evoked activity patterns for hand movements, Tomer Livne, DoHyun Kim, Nicholas V Metcalf, Lu Zhang, Lorenzo Pini, Gordon L Shulman, and Maurizio Corbetta

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Continuous NPWT regulates fibrosis in murine diabetic wound healing, Mengfan Wu, Dany Y Matar, Zhen Yu, Ziyu Chen, Samuel Knoedler, Brian Ng, Oliver A Darwish, Sadaf Sohrabi, Leigh Friedman, Valentin Haug, George F Murphy, Yuval Rinkevich, Dennis P Orgill, and Adriana C Panayi

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Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk, Xianyong Yin, Adam E Locke, Nathan O Stitziel, and et al.